Yanan Han
Phd Student
E-mail: yanan.han@ki.se
Visiting address: L8:05, CMM Karolinska Universitetssjukhuset Solna, 17176 Stockholm
Postal address: K8 Klinisk neurovetenskap, K8 Neuro Jagodic, 171 76 Stockholm
About me
- I am a Ph.D. student in Maja Jagodic's group of the Neuroimmunology Unit.
*Master of Natural Science in Bioinformatics*
Beijing Institute of Genomics, Chinese Academy of Sciences 09/2015-06/2018
Research Area: Epigenetic characteristics, regulation and function of RNA
transcriptional and translational processes
*Master of Science in Omics*
University of Southern Denmark 09/2015-07/2018
Research Area: Roles of RNA modifications in cancer
*Bachelor of Science, Department of Life Science*
Sichuan University (China) 09/2011-06/2015
Research Area: Identification of transcriptional regulators in hepatitis
patients
Research
- I am committed to the exploration of pathogenesis and treatments of Multiple
Sclerosis (MS) which is an autoimmune disease of the central nervous system
(CNS) affecting young adults in their most productive age. Both genetic and
environmental factors contribute to MS etiology, we therefore primarily focus
on epigenetic change and downstream influence in pathogenic immune cells.
DNA methylation, small RNA, and gene expression of cerebrospinal fluid
cells, memory B cells, and subtypes of T cells were reliably observed to
contribute to the MS pathogenesis and effect of treatments.
Articles
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Article: EPIGENETICS. 2022;17(10):1195-1204
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Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(17):e2011574118