Om mig

Sophie completed her PhD in the Department of Physiology at the University of Toronto and her first postdoctoral fellowship in the Department of Pharmacology and Therapeutics at McGill University.  In 2014, Sophie relocated to the Karolinska Institutet, Stockholm, Sweden in the Departments of Clinical Sciences, Intervention and Technology and Cellular and Molecular Biology and the Ludwig Cancer Institute.  In 2017, she started her first independent position as the Karolinska Institutet, where she is still still overseeing lab activities, and in July 2018 was recruited to the Centre de Recherché de Centre Hospitalier de l’Université de Montréal and the University of Montreal, Department of Medicine. 

Forskningsbeskrivning

She has merged 17 years of training expertise to formulate her unique research niche focused on human development, using cutting edge molecular biology techniques including single-cell genomic-sequencing (RNA, small noncoding RNA, methylation), single-molecule RNA FISH, imaging,  phenotyping, in vitro and in vivo models, and bioinformatics.  The overall goals of her innovative research program are to determine fundamental mechanism(s) underlying human embryo preimplantation development and to identify external factors that can reprogram the offspring’s life-trajectories manifesting as disease/disorders with ageing.   Findings from her work can also broadly be applied to stem cell biology and the improvement of Artificial Reproduction.

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