Sangram Nag

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Sangram Nag is working as the Head of Radiochemistry Research and
Development in Karolinska Institutet PET Centre, Institute för klinisk
neurovetenskap, Sektionen för Psykiatri, Karolinska Institutet, Karolinska
Sjukhuset, SE-171 76, Stockholm, Sweden. His present work responsibility
focusing on
* Research for developing new radio ligands and routine production of radio
ligands for clinical and preclinical use.
* Supervising new personnel and PhD students.
* Contact person with the industry research collaboration for developing new
radioligands.
* Writing scientific papers and grand application.
* Writing SOPs.
*Ph.D.* (Medicine): Karolinska Institutet, Stockholm, Sweden, 2007-2013.
*MPhil *(Organic Environmental Chemistry): University of Dhaka, Bangladesh,
2002-2004.
*M. Sc.* (Organic Chemistry): Kanpur University, Kanpur, UP, India,
1999-2001.
*B.Sc.* (Honours in Chemistry): University of Calcutta, Kolkata, WB, India,
1998.

Artiklar

Article: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2024;67(4):155-164

Automated radiosynthesis of mGluR5 PET tracer [18F]FPEB from aryl-chloro precursor and validation for clinical application.

Jahan M; Amir A; Das A; Kihlström J; Nag S
Article: PHARMACEUTICALS. 2024;17(2):250

Advancements in Microfluidic Cassette-Based iMiDEV™ Technology for Production of L-[11C]Methionine and [11C]Choline.

Mallapura H; Tanguy L; Mahfuz S; Bylund L; Långström B; Halldin C; Nag S
Article: MOLECULES. 2024;29(2):427

Synthesis of [11C]BIIB104, an α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic-Acid-Positive Allosteric Modulator, and Evaluation of the Bio-Distribution in Non-Human Primate Brains Using Positron Emission Tomography.

Nag S; Jia K; Arakawa R; Datta P; Scott D; Shaffer C; Moein MM; Hutchison M; Kaliszczak M; Halldin C
Article: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2023;8(1):42

Microfluidic-based production of [68Ga]Ga-FAPI-46 and [68Ga]Ga-DOTA-TOC using the cassette-based iMiDEV™ microfluidic radiosynthesizer.

Mallapura H; Ovdiichuk O; Jussing E; Thuy TA; Piatkowski C; Tanguy L; Collet-Defossez C; Långström B; Halldin C; Nag S
Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:108545

P-073 Discovery of [18F]F-687-TCO: An Optimized Tracer for Pretargeted PET Imaging in the CNS

Cook B; Pickel T; Jiang D; Bolduc P; Nag S; Tang S-P; Nasr K; Boscutti G; Plisson C; Morén A; Ochniewicz P; Halldin C; Peterson E; Martarello L; Kaliszczak M
Journal article: JOURNAL OF NUCLEAR MEDICINE. 2023;64(10):1588-1593

Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain.

Cook BE; Nag S; Arakawa R; Lin EY-S; Stratman N; Guckian K; Hering H; Lulla M; Choi J; Salinas C; Genung NE; Morén AF; Bolin M; Boscutti G; Plisson C; Martarello L; Halldin C; Kaliszczak MA
Article: JOURNAL OF NUCLEAR MEDICINE. 2023;64(10):1588-1593

Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain.

Cook BE; Nag S; Arakawa R; Lin EY-S; Stratman N; Guckian K; Hering H; Lulla M; Choi J; Salinas C; Genung NE; Morén AF; Bolin M; Boscutti G; Plisson C; Martarello L; Halldin C; Kaliszczak MA
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(17):3206-3211

PET Evaluation of the Novel F-18 Labeled Reversible Radioligand [18F]GEH200449 for Detection of Monoamine Oxidase-B in the Non-Human Primate Brain.

Varnäs K; Nag S; Halldin C; Farde L
Article: ACS CHEMICAL NEUROSCIENCE. 2023;14(14):2560-2568

Development of a Novel [11C]CO-Labeled Positron Emission Tomography Radioligand [11C]BIO-1819578 for the Detection of O-GlcNAcase Enzyme Activity.

Nag S; Bolin M; Datta P; Arakawa R; Forsberg Morén A; Khani Maynaq Y; Lin E; Genung N; Hering H; Guckian K; Martarello L; Kaliszczak M; Halldin C
Article: MOLECULES. 2023;28(12):4612

Characterization of a Novel M4 PAM PET Radioligand [11C]PF06885190 in Nonhuman Primates (NHP).

Nag S; Arakawa R; Jia Z; Lachapelle E; Zhang L; Maresca K; Chen L; Jahan M; Mccarthy T; Halldin C
Article: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2023;43(2):258-268

Quantification of the purinergic P2X7 receptor with [11C]SMW139 improves through correction for brain-penetrating radiometabolites.

Brumberg J; Aarnio R; Forsberg A; Marjamäki P; Kerstens V; Moein MM; Nag S; Wahlroos S; Kassiou M; Windhorst AD; Halldin C; Haaparanta-Solin M; Fazio P; Oikonen V; Rinne JO; Varrone A
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2023;66(1):641-656

Design and Evaluation of [18F]CHDI-650 as a Positron Emission Tomography Ligand to Image Mutant Huntingtin Aggregates.

Liu L; Johnson PD; Prime ME; Khetarpal V; Brown CJ; Anzillotti L; Bertoglio D; Chen X; Coe S; Davis R; Dickie AP; Esposito S; Gadouleau E; Giles PR; Greenaway C; Haber J; Halldin C; Haller S; Hayes S; Herbst T; Herrmann F; Heßmann M; Hsai MM; Khani Y; Kotey A; Lembo A; Mangette JE; Marriner GA; Marston RW; Mills MR; Monteagudo E; Forsberg-Morén A; Nag S; Orsatti L; Sandiego C; Schaertl S; Sproston J; Staelens S; Tookey J; Turner PA; Vecchi A; Veneziano M; Muñoz-Sanjuan I; Bard J; Dominguez C
Article: MOLECULES. 2022;27(24):8843

Production of [11C]Carbon Labelled Flumazenil and L-Deprenyl Using the iMiDEV™ Automated Microfluidic Radiosynthesizer.

Mallapura H; Tanguy L; Långström B; Meunier LL; Halldin C; Nag S
Article: JOURNAL OF NUCLEAR MEDICINE. 2022;63(12):1919-1924

First-in-Human Evaluation of 18F-PF-06445974, a PET Radioligand That Preferentially Labels Phosphodiesterase-4B.

Wakabayashi Y; Stenkrona P; Arakawa R; Yan X; Van Buskirk MG; Jenkins MD; Santamaria JAM; Maresca KP; Takano A; Liow J-S; Chappie TA; Varrone A; Nag S; Zhang L; Hughes ZA; Schmidt CJ; Doran SD; Mannes A; Zanotti-Fregonara P; Ooms M; Morse CL; Zoghbi SS; Halldin C; Pike VW; Innis RB
Journal article: ACS CHEMICAL NEUROSCIENCE. 2022;13(19):2932-2933

Correction to "Development of 11C-Labeled ASEM Analogues for Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR)".

Nag S; Miranda-Azpiazu P; Jia Z; Datta P; Arakawa R; Moein M; Yang Z; Tu Y; Lemoine L; Ågren H; Nordberg A; Långström B; Halldin C
Article: SYNAPSE. 2022;76(7-8):e22235

Decreased 5-HT1A binding in mild Alzheimer's disease-A positron emission tomography study.

Mattsson P; Cselényi Z; Andrée B; Borg J; Nag S; Halldin C; Farde L
Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:s122-s123

P-133 Automated radiolabeling of [68Ga]Ga-DOTATOC using the iMiDEV™ automated microfluidic radiosynthesizer

Chandrashekara HK; Tran T; Jussing E; Tanguy L; Långström B; Le Meunier L; Halldin C; Nag S
Journal article: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:s26

O-37 Synthesis and biological evaluation of a novel radioligand [11C] BIO-1790735 for detection of O-GlcNAcase (OGA) enzyme activity

Nag S; Arakawa R; Datta P; Morén A; Varrone A; Moein MM; Bolin M; Lin E; Genung N; Martarello L; Kaliszczak M; Halldin C
Article: EJNMMI RESEARCH. 2022;12(1):13

Target occupancy study and whole-body dosimetry with a MAGL PET ligand [11C]PF-06809247 in non-human primates.

Arakawa R; Takano A; Nag S; Jia Z; Amini N; Maresca KP; Zhang L; Keliher EJ; Butler CR; Piro JR; Samad TA; Smith D; Nason D; O'Neil S; Trapa P; Fonseca KR; Litchfield J; McCarthy T; Carson RE; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2022;13(3):352-362

Development of 11C-Labeled ASEM Analogues for the Detection of Neuronal Nicotinic Acetylcholine Receptors (α7-nAChR).

Nag S; Miranda-Azpiazu P; Jia Z; Datta P; Arakawa R; Moein MM; Yang Z; Tu Y; Lemoine L; Ågren H; Nordberg A; Långström B; Halldin C
Article: ACS CHEMICAL NEUROSCIENCE. 2021;12(24):4580-4586

PET Imaging of VMAT2 with the Novel Radioligand [18F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [11C]DTBZ and [18F]FE-DTBZ.

Nag S; Jahan M; Tóth M; Nakao R; Varrone A; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2021;64(16):12003-12021

[11C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological Proteins.

Liu L; Johnson PD; Prime ME; Khetarpal V; Lee MR; Brown CJ; Chen X; Clark-Frew D; Coe S; Conlon M; Davis R; Ensor S; Esposito S; Moren AF; Gai X; Green S; Greenaway C; Haber J; Halldin C; Hayes S; Herbst T; Herrmann F; Heßmann M; Hsai MM; Kotey A; Mangette JE; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Varnäs K; Varrone A; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: LAB ON A CHIP. 2021;21(11):2272-2282

Implementation of iMiDEV™, a new fully automated microfluidic platform for radiopharmaceutical production.

Ovdiichuk O; Mallapura H; Pineda F; Hourtané V; Långström B; Halldin C; Nag S; Maskali F; Karcher G; Collet C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(24):4398-4404

Synthesis and Autoradiography of Novel F-18 Labeled Reversible Radioligands for Detection of Monoamine Oxidase B.

Nag S; Jia Z; Svedberg M; Jackson A; Ahmad R; Luthra S; Varnäs K; Farde L; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(10):2429-2439

PET imaging of beta-secretase 1 in the human brain: radiation dosimetry, quantification, and test-retest examination of [18F]PF-06684511.

Arakawa R; Takano A; Stenkrona P; Stepanov V; Nag S; Jahan M; Grybäck P; Bolin M; Chen L; Zhang L; He P; Villalobos A; McCarthy TJ; Halldin C; Varrone A
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(15):8608-8633

Imaging Mutant Huntingtin Aggregates: Development of a Potential PET Ligand.

Liu L; Prime ME; Lee MR; Khetarpal V; Brown CJ; Johnson PD; Miranda-Azpiazu P; Chen X; Clark-Frew D; Coe S; Davis R; Dickie A; Ebneth A; Esposito S; Gadouleau E; Gai X; Galan S; Green S; Greenaway C; Giles P; Halldin C; Hayes S; Herbst T; Herrmann F; Heßmann M; Jia Z; Kiselyov A; Kotey A; Krulle T; Mangette JE; Marston RW; Menta S; Mills MR; Monteagudo E; Nag S; Nibbio M; Orsatti L; Schaertl S; Scheich C; Sproston J; Stepanov V; Svedberg M; Takano A; Taylor M; Thomas W; Toth M; Vaidya D; Vanräs K; Weddell D; Wigginton I; Wityak J; Mrzljak L; Munoz-Sanjuan I; Bard JA; Dominguez C
Article: ACS CHEMICAL NEUROSCIENCE. 2020;11(7):1048-1057

Synthesis, Biodistribution, and Radiation Dosimetry of a Novel mGluR5 Radioligand: 18F-AZD9272.

Nag S; Varnäs K; Arakawa R; Jahan M; Schou M; Farde L; Halldin C
Article: MOVEMENT DISORDERS. 2020;35(4):606-615

PET Molecular Imaging of Phosphodiesterase 10A: An Early Biomarker of Huntington's Disease Progression.

Fazio P; Fitzer-Attas CJ; Mrzljak L; Bronzova J; Nag S; Warner JH; Landwehrmeyer B; Al-Tawil N; Halldin C; Forsberg A; Ware J; Dilda V; Wood A; Sampaio C; Varrone A; PEARL-HD and LONGPDE10 study collaborators
Article: NEUROPHARMACOLOGY. 2020;162:107809

The pro-psychotic metabotropic glutamate receptor compounds fenobam and AZD9272 share binding sites with monoamine oxidase-B inhibitors in humans.

Varnäs K; Cselényi Z; Arakawa R; Nag S; Stepanov V; Moein MM; Johnström P; Kingston L; Elmore CS; Halldin C; Farde L
Article: EJNMMI RESEARCH. 2019;9(1):100

Potential for imaging the high-affinity state of the 5-HT1B receptor: a comparison of three PET radioligands with differing intrinsic activity.

Lindberg A; Arakawa R; Nogami T; Nag S; Schou M; Elmore CS; Farde L; Pike VW; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2019;78-79:11-16

Development of a 18F-labeled PET radioligand for imaging 5-HT1B receptors: [18F]AZ10419096.

Lindberg A; Nag S; Schou M; Arakawa R; Nogami T; Moein MM; Elmore CS; Pike VW; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2019;62(18):8532-8543

Identification and Development of an Irreversible Monoacylglycerol Lipase (MAGL) Positron Emission Tomography (PET) Radioligand with High Specificity.

Zhang L; Butler CR; Maresca KP; Takano A; Nag S; Jia Z; Arakawa R; Piro JR; Samad T; Smith DL; Nason DM; O'Neil S; McAllister L; Schildknegt K; Trapa P; McCarthy TJ; Villalobos A; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019;29(16):2270-2274

Synthesis and biological evaluation of [18F]fluorovinpocetine, a potential PET radioligand for TSPO imaging.

Nag S; Krasikova R; Airaksinen AJ; Arakawa R; Petukhovd M; Gulyas B
Article: MALARIA JOURNAL. 2019;18(1):252

Proof of concept: used malaria rapid diagnostic tests applied for parallel sequencing for surveillance of molecular markers of anti-malarial resistance in Bissau, Guinea-Bissau during 2014-2017.

Nag S; Ursing J; Rodrigues A; Crespo M; Krogsgaard C; Lund O; Aarestrup FM; Alifrangis M; Kofoed P-E
Journal article: ALZHEIMERS & DEMENTIA. 2019;15(7S_Part_31):p1630

O5‐06‐06: LIGANDS OF THE CORE ACETYLCHOLINE BIOSYNTHESIZING ENZYME, CHOLINE ACETYLTRANSFERASE, AS NOVEL AND POTENTIAL THERAPEUTIC AGENTS AND IN VIVO PET TRACERS FOR EARLY DIAGNOSIS OF ALZHEIMER'S DISEASE

Darreh-Shori T; Kumar R; Kumar A; Murumkar P; Nag S; Jia Z; Arakawa R; Leuzy A; Lemoine L; Nordberg A; Yadav MR; Halldin C; Långström B
Article: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. 2019;29(13):1624-1627

Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B.

Dahl K; Bernard-Gauthier V; Nag S; Varnäs K; Narayanaswami V; Mahdi Moein M; Arakawa R; Vasdev N; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2019;60(7):992-997

Quantitative Analysis of 18F-PF-06684511, a Novel PET Radioligand for Selective β-Secretase 1 Imaging, in Nonhuman Primate Brain.

Takano A; Chen L; Nag S; Brodney MA; Arakawa R; Chang C; Amini N; Doran SD; Dutra JK; McCarthy TJ; Nolan CE; O'Neill BT; Villalobos A; Zhang L; Halldin C
Article: MOLECULAR IMAGING AND BIOLOGY. 2019;21(3):500-508

Characterization of [11C]PXT012253 as a PET Radioligand for mGlu4 Allosteric Modulators in Nonhuman Primates.

Takano A; Nag S; Jia Z; Jahan M; Forsberg A; Arakawa R; Grybäck P; Duvey G; Halldin C; Charvin D
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2019;22(4):278-285

Venlafaxine ER Blocks the Norepinephrine Transporter in the Brain of Patients with Major Depressive Disorder: a PET Study Using [18F]FMeNER-D2.

Arakawa R; Stenkrona P; Takano A; Svensson J; Andersson M; Nag S; Asami Y; Hirano Y; Halldin C; Lundberg J
Article: NUCLEAR MEDICINE AND BIOLOGY. 2019;70:1-13

Synthesis and evaluation of two new candidate high-affinity full agonist PET radioligands for imaging 5-HT1B receptors.

Lindberg A; Lu S; Nag S; Schou M; Liow J-S; Zoghbi SS; Frankland MP; Gladding RL; Morse CL; Takano A; Amini N; Elmore CS; Lee YS; Innis RB; Halldin C; Pike VW
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2018;61(8):3296-3308

Identification of a Novel Positron Emission Tomography (PET) Ligand for Imaging β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE-1) in Brain.

Zhang L; Chen L; Dutra JK; Beck EM; Nag S; Takano A; Amini N; Arakawa R; Brodney MA; Buzon LM; Doran SD; Lanyon LF; McCarthy TJ; Bales KR; Nolan CE; O'Neill BT; Schildknegt K; Halldin C; Villalobos A
Article: MALARIA JOURNAL. 2018;17(1):91

Direct whole-genome sequencing of Plasmodium falciparum specimens from dried erythrocyte spots.

Nag S; Kofoed P-E; Ursing J; Lemvigh CK; Allesøe RL; Rodrigues A; Svendsen CA; Jensen JD; Alifrangis M; Lund O; Aarestrup FM
Article: ALZHEIMERS RESEARCH & THERAPY. 2017;9(1):96

Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains.

Lemoine L; Gillberg P-G; Svedberg M; Stepanov V; Jia Z; Huang J; Nag S; Tian H; Ghetti B; Okamura N; Higuchi M; Halldin C; Nordberg A
Article: EJNMMI RESEARCH. 2017;7(1):54

Test-retest reproducibility of [11C]-L-deprenyl-D2 binding to MAO-B in the human brain.

Arakawa R; Stenkrona P; Takano A; Nag S; Maior RS; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2017;54:34-40

[11C]AZ10419096 - a full antagonist PET radioligand for imaging brain 5-HT1B receptors.

Lindberg A; Nag S; Schou M; Takano A; Matsumoto J; Amini N; Elmore CS; Farde L; Pike VW; Halldin C
Journal article: ALZHEIMERS & DEMENTIA. 2017;13(7S_Part_3):p139-p140

[IC‐P‐189]: COMPARISON OF BINDING PROPERTIES OF THK5117, THK5351, PBB3 AND T807 IN AUTOPSIES OF ALZHEIMER DISEASE CASES

Lemoine L; Gillberg P; Svedberg M; Stepanov V; Nag S; Tian H; Higuchi M; Halldin C; Nordberg A
Journal article: ALZHEIMERS & DEMENTIA. 2017;13(7S_Part_28):p1390

[P4–274]: COMPARISON OF BINDING PROPERTIES OF THK5117, THK5351, PBB3 AND T807 IN AUTOPSIES OF ALZHEIMER DISEASE CASES

Lemoine L; Gillberg P; Svedberg M; Stepanov V; Nag S; Tian H; Higuchi M; Halldin C; Nordberg A
Article: SCIENTIFIC REPORTS. 2017;7(1):2398

High throughput resistance profiling of Plasmodium falciparum infections based on custom dual indexing and Illumina next generation sequencing-technology.

Nag S; Dalgaard MD; Kofoed P-E; Ursing J; Crespo M; Andersen LO; Aarestrup FM; Lund O; Alifrangis M
Article: NEUROIMAGE. 2017;152:330-339

Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D2/3 receptors and sub-cortical volumes in the human basal ganglia: A PET study with 18F-MNI-659 and 11C-raclopride with correction for partial volume effect.

Fazio P; Schain M; Mrzljak L; Amini N; Nag S; Al-Tawil N; Fitzer-Attas CJ; Bronzova J; Landwehrmeyer B; Sampaio C; Halldin C; Varrone A
Article: NEUROPHARMACOLOGY. 2017;117:171-181

In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects.

Delnomdedieu M; Forsberg A; Ogden A; Fazio P; Yu C-R; Stenkrona P; Duvvuri S; David W; Al-Tawil N; Vitolo OV; Amini N; Nag S; Halldin C; Varrone A
Article: JOURNAL OF NUCLEAR MEDICINE. 2017;58(4):617-622

Longitudinal Small-Animal PET Imaging of the zQ175 Mouse Model of Huntington Disease Shows In Vivo Changes of Molecular Targets in the Striatum and Cerebral Cortex.

Häggkvist J; Tóth M; Tari L; Varnäs K; Svedberg M; Forsberg A; Nag S; Dominguez C; Munoz-Sanjuan I; Bard J; Wityak J; Varrone A; Halldin C; Mrzljak L
Article: JOURNAL OF NUCLEAR MEDICINE. 2016;57(2):315-320

In Vivo and In Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18F-Labeled Deuterated Fluorodeprenyl.

Nag S; Fazio P; Lehmann L; Kettschau G; Heinrich T; Thiele A; Svedberg M; Amini N; Leesch S; Catafau AM; Hannestad J; Varrone A; Halldin C
Article: JOURNAL OF NUCLEAR MEDICINE. 2015;56(5):714-720

Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease.

Fazio P; Svenningsson P; Forsberg A; Jönsson EG; Amini N; Nakao R; Nag S; Halldin C; Farde L; Varrone A
Article: NUCLEAR MEDICINE AND BIOLOGY. 2015;42(4):387-394

Synthesis and biological evaluation of [¹¹C]AZ12504948; a novel tracer for imaging of glucokinase in pancreas and liver.

Jahan M; Johnström P; Nag S; Takano A; Korsgren O; Johansson L; Halldin C; Eriksson O
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2015;42(3):438-446

Positron emission tomography imaging of the 18-kDa translocator protein (TSPO) with [18F]FEMPA in Alzheimer's disease patients and control subjects.

Varrone A; Oikonen V; Forsberg A; Joutsa J; Takano A; Solin O; Haaparanta-Solin M; Nag S; Nakao R; Al-Tawil N; Wells LA; Rabiner EA; Valencia R; Schultze-Mosgau M; Thiele A; Vollmer S; Dyrks T; Lehmann L; Heinrich T; Hoffmann A; Nordberg A; Halldin C; Rinne JO
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(21):6634-6641

Development of a novel fluorine-18 labeled deuterated fluororasagiline ([(18)F]fluororasagiline-D2) radioligand for PET studies of monoamino oxidase B (MAO-B).

Nag S; Lehmann L; Kettschau G; Toth M; Heinrich T; Thiele A; Varrone A; Halldin C
Article: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40(6):921-931

In vivo imaging of the 18-kDa translocator protein (TSPO) with [18F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients.

Varrone A; Mattsson P; Forsberg A; Takano A; Nag S; Gulyás B; Borg J; Boellaard R; Al-Tawil N; Eriksdotter M; Zimmermann T; Schultze-Mosgau M; Thiele A; Hoffmann A; Lammertsma AA; Halldin C
Article: EJNMMI RESEARCH. 2013;3(1):30

In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106.

Takano A; Piehl F; Hillert J; Varrone A; Nag S; Gulyás B; Stenkrona P; Villemagne VL; Rowe CC; Macdonell R; Tawil NA; Kucinski T; Zimmermann T; Schultze-Mosgau M; Thiele A; Hoffmann A; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2013;21(1):186-195

Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.

Nag S; Kettschau G; Heinrich T; Varrone A; Lehmann L; Gulyas B; Thiele A; Keller É; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2012;20(9):3065-3071

Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).

Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Varrone A; Gulyas B; Halldin C
Article: NUCLEAR MEDICINE AND BIOLOGY. 2012;39(3):315-323

Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[18F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography.

Jahan M; Nag S; Krasikova R; Weber U; Muhs A; Pfeifer A; Spenger C; Willbold D; Gulyás B; Halldin C
Article: SYNAPSE. 2012;66(4):323-330

In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand.

Nag S; Varrone A; Tóth M; Thiele A; Kettschau G; Heinrich T; Lehmann L; Halldin C
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2011;54(20):7023-7029

Synthesis of three novel fluorine-18 labeled analogues of L-deprenyl for positron emission tomography (PET) studies of monoamine oxidase B (MAO-B).

Nag S; Lehmann L; Heinrich T; Thiele A; Kettschau G; Nakao R; Gulyás B; Halldin C
Article: PSYCHOPHARMACOLOGY. 2011;216(2):279-286

NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo.

Takano A; Nag S; Gulyás B; Halldin C; Farde L
Article: NEUROCHEMISTRY INTERNATIONAL. 2011;58(1):60-68

Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography.

Gulyás B; Pavlova E; Kása P; Gulya K; Bakota L; Várszegi S; Keller E; Horváth MC; Nag S; Hermecz I; Magyar K; Halldin C
Article: NEUROCHEMISTRY INTERNATIONAL. 2010;56(6-7):789-798

The norepinephrine transporter (NET) radioligand (S,S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer's disease: a post-mortem autoradiographic study.

Gulyás B; Brockschnieder D; Nag S; Pavlova E; Kása P; Beliczai Z; Légrádi A; Gulya K; Thiele A; Dyrks T; Halldin C
Article: APPLIED RADIATION AND ISOTOPES. 2009;67(1):73-78

A fully automated one-pot synthesis of [carbonyl-11C]WAY-100635 for clinical PET applications.

Krasikova RN; Andersson J; Truong P; Nag S; Shchukin EV; Halldin C
Article: BIOORGANIC & MEDICINAL CHEMISTRY. 2008;16(13):6467-6473

[11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors.

Airaksinen AJ; Nag S; Finnema SJ; Mukherjee J; Chattopadhyay S; Gulyás B; Farde L; Halldin C
Article: DIABETOLOGIA. 2004;47(Suppl 1):a1-a464

40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004.
Article: DIABETOLOGIA. 1999;42(Suppl 1):a1-a330

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999.
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Alla övriga publikationer

Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2023;50(SUPPL 1):S257

In vivo quantification of [¹¹C]BIO-1819578, a novel radioligand for O-GlcNAcase, in non-human primates using Positron Emission Tomography

Bolin M; Nag S; Datta P; Arakawa R; Meynaq YK; Lin E; Genung N; Hering H; Guckian K; Martarello L; Kaliszczak M; Farde L; Stenkrona P; Halldin C; Moren AF
Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2023;126:S111-S112

Discovery of [¹⁸F]F-687-TCO: An Optimized Tracer for Pretargeted PET Imaging in the CNS

Cook B; Pickel T; Jiang D; Bolduc P; Nag S; Tang S-P; Nasr K; Boscutti G; Plisson C; Moren A; Ochniewicz P; Halldin C; Peterson E; Martarello L; Kaliszczak M
Review: EJNMMI RADIOPHARMACY AND CHEMISTRY. 2022;7(1):18

Practical considerations for navigating the regulatory landscape of non-clinical studies for clinical translation of radiopharmaceuticals.

Korde A; Mikolajczak R; Kolenc P; Bouziotis P; Westin H; Lauritzen M; Koole M; Herth MM; Bardiès M; Martins AF; Paulo A; Lyashchenko SK; Todde S; Nag S; Lamprou E; Abrunhosa A; Giammarile F; Decristoforo C
Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:S122-S123

Automated radiolabeling of [⁶⁸Ga]Ga-DOTATOC using the iMiDEV™ automated microfluidic radiosynthesizer

Chandrashekara HK; Thuy T; Jussing E; Tanguy L; Langstrom B; Le Meunier L; Halldin C; Nag S
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2022;49(SUPPL 1):S238

Development of a novel ¹¹CO labelled PET radioligand ¹¹C-BIO-1819578 for the detection of O-GlcNAcase (OGA) enzyme in the living brain

Nag S; Arakawa R; Datta P; Forsberg A; Moein M; Bolin M; Lin T; Genung N; Heiring H; Guckian K; Martarello L; Kaliszczak M; Halldin C
Conference publication: NUCLEAR MEDICINE AND BIOLOGY. 2022;108:S26

Synthesis and biological evaluation of a novel radioligand [¹¹C]BIO-1790735 for detection of O-GlcNAcase (OGA) enzyme activity

Nag S; Arakawa R; Datta P; Moren A; Varrone A; Moein MM; Bolin M; Lin E; Genung N; Martarello L; Kaliszczak M; Halldin C
Preprint: RESEARCH SQUARE. 2021

Target Occupancy Study and Whole-Body Dosimetry with a MAGL PET Ligand 11C-PF-06809247 in non-human Primates

Arakawa R; Takano A; Nag S; Jia Z; Amini N; Maresca K; Zhang L; Keliher E; Butler C; Piro J; Samad T; Smith D; Nason D; O’Neil S; Trapa P; Fonseca K; Litchfield J; McCarthy T; Carson R; Halldin C
Preprint: RESEARCH SQUARE. 2021

Target Occupancy Study and Whole-Body Dosimetry With a MAGL PET Ligand 11C-PF-06809247 in Non-Human Primates

Arakawa R; Takano A; Nag S; Jia Z; Amini N; Maresca KP; Zhang L; Keliher EJ; Butler CR; Piro JR; Samad TA; Smith D; Nason D; O’Neil S; Trapa P; Fonseca KR; Litchfield J; McCarthy T; Carson RE; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2021;48(SUPPL 1):S223-S224

Radiosynthesis of [¹¹C]Flumazenil and [¹¹C]Deprenyl using a fully automated iMiDEV microfluidic radiosynthesizer

Chandrashekara HM; Tanguy L; Langstrom B; Le Meunier L; Halldin C; Nag S
Corrigendum: MOVEMENT DISORDERS. 2020;35(12):2363-2364

Corrigendum.
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2020;47(SUPPL 1):S493-S494

A Positron Emission Tomography (PET) Study to Examine the Brain Binding of[¹¹C]-PXT012253 in Healthy Subjects

Stenkrona P; Arakawa R; Holst H; Nag S; Moein MM; Jia Z; Halldin C; Varrone A
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S322-S323

Norepinephrine transporter occupancy of venlafaxine in patients with major depressive disorder using positron emission tomography and [18F]FMeNERD2

Arakawa R; Stenkrona P; Takano A; Svensson J; Andersson M; Nag S; Asami Y; Halldin C; Lundberg J
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(SUPPL 1):S228

Development of novel ¹¹C- labeled ASEM analogs for detection of neuronal nicotinic acetylcholine receptors (α7-nAChR)

Nag S; Jia Z; Datta P; Azpiazu PM; Arakawa R; Varnas K; Lemoine L; Kuang G; Agren H; Langstram B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2019;46(SUPPL 1):S852

Development of a M4 PAM PET radioligand - [¹¹C]PF-06885190-for a study in nonhuman primates

Nag S; Arakawa R; Maresca K; Butler C; Chen L; Jia Z; Lachapelle E; Jahan M; McCarthy T; Zhang L; Halldin C
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2019;39:84

PET imaging of [¹¹C]BIIB104, an AMPA positive modulator, in the living NHP brain

Kaliszczak M; Nag S; Dandapani S; Arakawa R; Forsberg A; Varnas K; Beaver J; Shaffer C; Halldin C; Martarello L
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2019;62:S391

Evaluation of the brain bio-distribution of [¹¹C]BIIB104, an AMPA positive allosteric modulator in the living NHP brain using positron emission tomography

Nag S; Jia Z; Arakawa R; Varnas K; Mohammad M; Datta P; Scott D; Shaffer C; Hutchison M; Kaliszczak M; Martarello L; Halldin C
Preprint: BIORXIV. 2018

Proof of concept: Malaria rapid diagnostic tests and massively parallel sequencing for surveillance of molecular markers of antimalarial resistance in Bissau, Guinea-Bissau during 2014-2017

Nag S; Ursing J; Rodrigues A; Crespo M; Krogsgaard C; Lund O; Aarestrup F; Alifrangis M; Kofoed P-E
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S213

PET Imaging of Beta-secretase 1 in The Human Brain: Quantification and Test-Retest Examination with [¹⁸F]PF-06684511

Varrone A; Arakawa R; Takano A; Stenkrona P; Nag S; Stepanov V; Jahan M; Chen L; He P; Villalobos A; McCarthy T; Halldin C
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2018;43:S133-S134

Quantification of Norepinephrine Transporter Occupancy of Venlafaxine Extended-Release in Patients With Major Depressive Disorder Using Positron Emission Tomography and Radioligand [18 F]FMeNER-D2

Arakawa R; Stenkrona P; Takano A; Svensson J; Andersson M; Nag S; Asamin Y; Hirano Y; Halldin C; Lundberg J
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S643-S644

New candidate high-affinity full agonist PET radioligands for imaging 5-HT_1Breceptors have very low brain uptake and no signal

Lindberg A; Lu S; Liow J; Zoghbi S; Frankland MP; Gladding RL; Innis RB; Nag S; Schou M; Elmore CS; Halldin C; Pike VW
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S144

Recent advances in translational study of ¹⁸F-DABTA-11, a PET tracer for alpha-synuclein aggregates

Yousefi BH; Shi K; Nag S; Arakawa R; Herz M; Braeuer M; Reder S; Halldin C; Wester H; Schwaiger M; Weber W; Arzberger T; Yakushev I
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S660-S661

Evaluation of [¹¹C]PXT012253 and [¹⁸F]PXT012251 as PET radioligands for mGlu4 allosteric modulators in non-human primates

Nag S; Arakawa R; Takano A; Jia Z; Jahan M; Forsberg A; Duvey G; Halldin C; Charvin D
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S222-S223

Development of the first ¹⁸F-labeled PET radioligand for imaging 5-HT _1Breceptors: [¹⁸F]AZ10419096

Lindberg A; Nag S; Moein M; Schou M; Arakawa R; Elmore CS; Pike VW; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S143-S144

Synthesis and biological evaluation of a novel mGluR5 radioligand: [¹⁸F]AZD9272

Nag S; Varnas K; Arakawa R; Takano A; Jahan M; Schou M; Halldin C; Farde L
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2018;45:S142-S143

Development of a novel reversible F-18 labelled SL25.1188 analog for the detection of MAO-B activity

Nag S; Dahl K; Bernard-Gauthier V; Varnas K; Narayanaswami V; Moein M; Arakawa R; Vasdev N; Halldin C
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2018;59

Synthesis of a novel ¹⁸F-labeled radioligand for monoamine oxidase-B and preliminary PET imaging in non-human primate

Dahl K; Bernard-Gauthier V; Nag S; Varnaosi K; Narayanaswami V; Moein M; Arakawa R; Vasdev N; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S367-S368

Radiosynthesis, initial evaluation and whole-body dosimetry of a beta-secretase (BACE) PET radioligand [¹¹C] PF-06684511 in non-human

Arakawa R; Chen L; Takano A; Brodney MA; Dutra J; Stepanov V; Nag S; Doran S; McCarthy T; Nolan C; Villalobos A; Zhang L; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S172

Human Whole-body Biodistribution and Radiation Dosimetry of [¹⁸F]PF-06684511, a Novel Radioligand for Brain Imaging of Beta-secretase

Varrone A; Arakawa R; Takano A; Nag S; Stepanov V; Stenkrona P; Gryback P; Bolin M; Chen L; Zhang L; He P; Villalobos A; McCarthy T; Halldin C
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2017;60:S77

Development of BACE-selective PET LIGANDS - [¹⁸F]/[¹¹C]PF-06684511

Nag S; Stepanov V; Takano A; Chen L; Brodney MA; Arakawa A; Doran J; Dutra C; Neill BO; Buzon L; Nolan CE; Mccarthy T; Mccarthy T; Villalobos A; Bales K; Zhang L; Halldin C
Conference publication: MOVEMENT DISORDERS. 2017;32

Imaging of phosphodiesterase 10 A (PDE10A) enzyme levels in the living human brain of Huntington's disease gene expansion carriers and healthy controls with positron emission tomography.

Fazio P; Fittzer-Attas C; Bronzova J; Nag S; Warner J; Landwehrmeyer B; Al-Tawil N; Halldin C; Mrzljak L; Sampaio C; Varrone A
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S364-S365

Injected Mass is a Limiting Factor for Small Animal PET Studies Using High-Affinity Radioligands: Evidence from a Study Using [11C]- and [18F]Fallypride

Toth M; Nag S; Jia Z; Haggkvist J; Mukherjee J; Varrone A; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S366-S367

Identification and development of a highly specific monoacylglycerol lipase (MAGL) PET tracer ¹¹C-PF-06809247

Butler CR; Takano A; Nag S; Arakawa R; Maresca KP; Piro JR; Samad T; Smith D; Nason D; O'Neil S; McAllister L; Grimwood S; Trapa P; McCarthy T; Villalobos A; Halldin C; Zhang L
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2017;44:S265

Synthesis and biological evaluation of novel five F-18 labelled radioligands for detection of MAO-B activity

Nag S; Jackson A; Takano A; Jia K; Arakawa R; Jahan M; Ahmad R; Luthra S; Maior R; Halldin C
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2017;58

Radiosynthesis of [¹¹C] SL25.1188 via "in-Loop" [¹¹C] CO₂ Fixation: Pre-clinical Evaluation for MAO-B Activity in Alzheimer's Disease

Dahl K; Collier T; Cheng R; Svedberg M; Toth M; Das A; Nag S; Liang S; Halldin C; Vasdev N
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2016;43:S99-S100

Target occupancy of PF-06663195 measured with a beta-secretase (BACE) PET radioligand [¹⁸F] PF-06684511 in non-human primates

Arakawa R; Chen L; Takano A; Brodney MA; Nag S; Chang C; Amini N; Doran S; McCarthy T; Nolan C; Zhang L; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2016;43:S94-S95

Radio-labeling and initial evaluation of a novel beta-secretase (BACE)-selective PET radioligand, [¹⁸F] PF-06684511, in nonhuman primates

Takano A; Chen L; Nag S; Brodney MA; Amini N; Chang C; Arakawa R; Doran S; Dutra J; McCarthy T; Nolan C; O'Neil B; Villalobos A; Zhang L; Halldin C
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2016;36:614-615

MAPPING MAO-B WITH FLUORINE-18 LABELED DEUTERATED FLUORODEPRENYL (18F-FLUORODEPRENYL-D2). DEVELOPMENT, IN VITRO AUTORADIOGRAPHY AND IN VIVO EVALUATION IN NON-HUMAN PRIMATES.

Nag S; Fazio P; Svedberg M; Amini N; Lehmann L; Kettschau G; Heinrich T; Leesch S; Catafau A; Varrone A; Halldin C
Conference publication: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2015;93(4):458

NEXT-GENERATION SEQUENCING PLATFORM BASED ON MALARIA RAPID DIAGNOSTIC TESTS FOR SURVEILLANCE OF ANTIMALARIAL DRUG RESISTANCE

Nag S; Dalgaard M; Ndiaye M; Kofoed P-EL; Rodrigues A; Ursing J; Kavishe R; Alifrangis M; Lund O; Aarestrup FM
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2014;55

The automated receptor imaging system (ARIS) for quantitative image processing to estimate binding parameters for dopamine transporter [18F]FE-PE2I studies in non-human primate (NHP)

Odano I; Guenther I; Wang Z; Serrano R; Gsell W; Chang YQ; Nag S; Chimon G; Varrone A; Halldin C
Conference publication: JOURNAL OF NUCLEAR MEDICINE. 2014;55

The automated receptor imaging system (ARIS) for quantitative image processing to estimate binding parameters for dopamine transporter [18F]FE-PE2I studies in non-human primate (NHP)

Odano I; Guenther I; Wang Z; Serrano R; Gsell W; Chang YQ; Nag S; Chimon G; Varrone A; Halldin C
Thesis / dissertation: 2013

Development of novel fluorine-18 labeled PET radioligands for monoamine oxidase B (MAO-B)

Nag, Sangram
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2013;40:S199

Development of Novel F-18 Labeled Deuterated Analogues of Fluorodeprenyl and Fluororasagiline by PET to Study MAO-B Activity

Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Toth M; Halldin C
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2013;56:S310

Synthesis and evaluation of novel F-18 labeled deuterated fluororasagilineby PET to study MAO-B activity

Nag S; Lehmann L; Kettschau G; Thiele A; Varrone A; Toth M; Gulyas B; Dinkelborg L; Halldin C
Book chapter: RADIOCHEMICAL SYNTHESES. 2012;p. 265-273

Synthesis of [carbonyl‐11C]Way‐100635

Andersson JD; Nag S; Krasikova RN; Pike VW; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2012;39:S182

Initial Evaluation of the Novel Dopamine Transporter Radioligand [18F]FE-PE2I in Healthy Controls and Parkinson's Disease Patients

Varrone A; Forsberg A; Nakao R; Amini N; Nag S; Svenningsson P; Halldin C; Farde L
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2012;32:S101-S102

Synthesis and PET evaluation of a novel F-18 labeled deuterated fluorodeprenyl ([¹⁸F]fluorodeprenyl-D2) radioligand to study MAO-B activity

Nag S; Lehmann L; Kettschau G; Heinrich T; Thiele A; Varrone A; Gulyas B; Halldin C
Conference publication: JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM. 2012;32:S70-S71

Preliminary evaluation of the quantification and metabolism in human subjects of the dopamine transporter redioligand [¹⁸F]FE-PE21

Vantone A; Nakao R; Amini N; Forberg A; Nag S; Farde L; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2012;39:S267

Synthesis and Biological Evaluation of Novel F-18 Labeled Radioligands for Detection of MAO-B Activity

Nag S; Lehmann L; Kettschau G; Thiele A; Heinrich T; Varrone A; Gulyas B; Halldin C
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2011;21:S320-S321

In vivo monoamine transporter occupancy by venlafaxine and milnacipran in non-human primates

Takano A; Nag S; Halldin C; Farde L
Conference publication: JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS. 2011;54:S269

Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel PET radioligand for MAO-B

Nag S; Lehmann L; Kettschau G; Thiele A; Varrone A; Gulyas B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S148

PET investigation of in vivo SERT and NET occupancy by venlafaxine and milnacipran in non-human primates

Takano A; Nag S; Halldin C; Farde L
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S123

In Vivo Imaging of the 18-kDa Translocator Protein (TSPO) with [18F]FEDAA1106 and PET Does Not Show Increased Binding In Alzheimer's Disease Patients

Varrone A; Mattsson P; Forsberg A; Takano A; Nag S; Boellaard R; Al Tawil N; Joenhagen ME; Hoffmann A; Zimmermann T; Schultze-Mosgau M; Thiele A; Lammertsma AA; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2011;38:S107

In vivo TSPO imaging in patients with Multiple Sclerosis: A PET study with [18F]FEDAA1106

Takano A; Piehl F; Hillert J; Varrone A; Nag S; Villemagne V; Rowe CC; Macdonell R; Al Tawil N; Kucunski T; Hoffmann A; Zimmermann T; Schultze-Mosgau M; Thiele A; Halldin C
Meeting abstract: NEUROIMAGE. 2010;52:S121

Synthesis of three F-18 labeled analogues of 1-deprenyl for PET Studies of monoamine oxidase B

Nag S; Lehmann L; Kettschau G; Heinrich T; Brumby T; Thiele A; Varrone A; Gulyas B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2010;37:S205

A Fluorine-18 Labeled Deprenyl PET Radioligand For in vivo Evaluation of MAO-B

Nag S; Lehmann L; Kettschau G; Heinrich T; Brumby T; Thiele A; Varrone A; Gulyas B; Halldin C
Meeting abstract: NEUROIMAGE. 2006;31:T15

A new PET radioligand [11C]cyclopropyl-FLB 457 for imaging extrastriatal dopamine D2 receptors:: Evaluation in monkey and comparison to [11C]FLB 457 and [11C]Fallypride

Airaksinen AJ; Finnema SJ; Nag S; Mukherjee J; Gulyas B; Halldin C
Conference publication: EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING. 2006;33:S211

[¹¹C] Cyclopropyl-FLB 457:: PET examination of a more D2 selective high affinity radioligand for extrastriatal D2 dopamine receptors

Airaksinen AJ; Finnema S; Nag S; Mukherjee J; Farde L; Halldin C
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Forskningsbidrag

Development of PET tracer for imaging SV2C in Parkinson´s disease

Michael J. Fox Foundation for Parkinson's Research

1 January 2023 - 31 December 2025
Development of an imaging marker for synaptic vesicular glycoprotein SV2C: a specific target for synaptic density in Parkinson´s disease

Swedish Research Council

1 January 2021 - 31 December 2023

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Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2022-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för klinisk neurovetenskap, Karolinska Institutet, 2013

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