Nils Lindefors

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

Nils Lindefors tog läkarexamen MD 1982 och doktorsexamen I farmakologi 1987,
i båda fallen vid Karolinska Institutet (KI). Han utnämndes till docent i
farmakologi vid KI 1990 och i psykiatri 1999
Nils Lindefors har varit prövningsansvarig (PI) för kliniska prövningar
både för farmakoterapi och psykologisk behandling (internet-KBT). NL
påbörjade klinisk implementeringsforskning för internetförmedlad kognitiv
beteendeterapi (IKBT) 2002. NL utnämndes 2006 till klinikchef för
universitetskliniken Psykiatri Sydväst vid Huddinge sjukhus 2006. År 2007
initierades klinisk IKBT vid Psykiatri Sydväst. Mellan 2006 och 2018 var NL
professor i psykiatri (adjungerad) vid Karolinska Institutet.
2019 slutade NL som chef vid Psykiatri Sydväst och är fn verksam inom FoUU
vid Stockholms läns sjukvårdsområde inom Region Stockholm, bl a som
ansvarig för ett utvecklingsprojekt för digitalt stöd för egenvård, med
statlig finansiering.

Artiklar

Article: BMJ OPEN. 2023;13(10):e069427

Swedish multimodal cohort of patients with anxiety or depression treated with internet-delivered psychotherapy (MULTI-PSYCH).

Boberg J; Kaldo V; Mataix-Cols D; Crowley JJ; Roelstraete B; Halvorsen M; Forsell E; Isacsson NH; Sullivan PF; Svanborg C; Andersson EH; Lindefors N; Kravchenko O; Mattheisen M; Danielsdottir HB; Ivanova E; Boman M; Fernández de la Cruz L; Wallert J; Rück C
Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2023;33:100636

Internet delivered cognitive behavioral therapy for adults with ADHD - A randomized controlled trial.

Nasri B; Cassel M; Enhärje J; Larsson M; Hirvikoski T; Ginsberg Y; Lindefors N; Kaldo V
Article: JOURNAL OF SLEEP RESEARCH. 2023;32(2):e13759

Treatment feasibility of a digital tool for brief self-help behavioural therapy for insomnia (FastAsleep).

Jernelöv S; Forsell E; Westman H; Eriksson Dufva Y; Lindefors N; Kaldo V; Kraepelien M
Article: JMIR DERMATOLOGY. 2023;6:e42360

A Digital Self-help Intervention for Atopic Dermatitis: Analysis of Secondary Outcomes From a Feasibility Study.

Kern D; Ljótsson B; Lönndahl L; Hedman-Lagerlöf E; Bradley M; Lindefors N; Kraepelien M
Article: BMJ OPEN. 2023;13(2):e068908

Brief self-guided digital intervention versus a comprehensive therapist-guided online cognitive behavioural therapy for atopic dermatitis: a trial protocol for a randomised non-inferiority trial.

Kern D; Ljótsson B; Lönndahl L; Hedman-Lagerlöf E; Bradley M; Lindefors N; Kraepelien M
Article: BMC PSYCHIATRY. 2022;22(1):701

The 14-item short health anxiety inventory (SHAI-14) used as a screening tool: appropriate interpretation and diagnostic accuracy of the Swedish version.

Österman S; Axelsson E; Lindefors N; Hedman-Lagerlöf E; Hedman-Lagerlöf M; Kern D; Svanborg C; Ivanov VZ
Article: JMIR FORMATIVE RESEARCH. 2022;6(7):e32950

Online Guided Self-help Cognitive Behavioral Therapy With Exposure to Anxiety and Problem Solving in Type 1 Diabetes Mellitus: Case Study.

Kern D; Ljótsson B; Bonnert M; Lindefors N; Kraepelien M
Article: BJPSYCH OPEN. 2022;8(2):e43

A self-guided and monitored digital problem-solving intervention for patients with symptoms of depression or anxiety on the waiting list for treatment in routine psychiatric care: feasibility study.

Hentati A; Forsell E; Ljótsson B; Lindefors N; Kraepelien M
Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2021;26:100448

The effect of user interface on treatment engagement in a self-guided digital problem-solving intervention: A randomized controlled trial.

Hentati A; Forsell E; Ljótsson B; Kaldo V; Lindefors N; Kraepelien M
Article: MOLECULAR PSYCHIATRY. 2021;26(8):4179-4190

Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.

Forstner AJ; Awasthi S; Wolf C; Maron E; Erhardt A; Czamara D; Eriksson E; Lavebratt C; Allgulander C; Friedrich N; Becker J; Hecker J; Rambau S; Conrad R; Geiser F; McMahon FJ; Moebus S; Hess T; Buerfent BC; Hoffmann P; Herms S; Heilmann-Heimbach S; Kockum I; Olsson T; Alfredsson L; Weber H; Alpers GW; Arolt V; Fehm L; Fydrich T; Gerlach AL; Hamm A; Kircher T; Pané-Farré CA; Pauli P; Rief W; Ströhle A; Plag J; Lang T; Wittchen H-U; Mattheisen M; Meier S; Metspalu A; Domschke K; Reif A; Hovatta I; Lindefors N; Andersson E; Schalling M; Mbarek H; Milaneschi Y; de Geus EJC; Boomsma DI; Penninx BWJH; Thorgeirsson TE; Steinberg S; Stefansson K; Stefansson H; Müller-Myhsok B; Hansen TF; Børglum AD; Werge T; Mortensen PB; Nordentoft M; Hougaard DM; Hultman CM; Sullivan PF; Nöthen MM; Woldbye DPD; Mors O; Binder EB; Rück C; Ripke S; Deckert J; Schumacher J
Article: BMC GASTROENTEROLOGY. 2021;21(1):289

Return on investment of internet delivered exposure therapy for irritable bowel syndrome: a randomized controlled trial.

Wallén H; Lindfors P; Andersson E; Hedman-Lagerlöf E; Hesser H; Lindefors N; Svanborg C; Ljótsson B
Article: JAMA DERMATOLOGY. 2021;157(7):796-804

Internet-Delivered Cognitive Behavior Therapy for Atopic Dermatitis: A Randomized Clinical Trial.

Hedman-Lagerlöf E; Fust J; Axelsson E; Bonnert M; Lalouni M; Molander O; Agrell P; Bergman A; Lindefors N; Bradley M
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;44:105-120

Therapygenetic effects of 5-HTTLPR on cognitive-behavioral therapy in anxiety disorders: A meta-analysis.

Schiele MA; Reif A; Lin J; Alpers GW; Andersson E; Andersson G; Arolt V; Bergström J; Carlbring P; Eley TC; Esquivel G; Furmark T; Gerlach AL; Hamm A; Helbig-Lang S; Hudson JL; Lang T; Lester KJ; Lindefors N; Lonsdorf TB; Pauli P; Richter J; Rief W; Roberts S; Rück C; Schruers KRJ; Thiel C; Wittchen H-U; Domschke K; Weber H; Lueken U
Article: JOURNAL OF PARKINSONS DISEASE. 2020;10(2):653-664

Individually Tailored Internet-Based Cognitive-Behavioral Therapy for Daily Functioning in Patients with Parkinson's Disease: A Randomized Controlled Trial.

Kraepelien M; Schibbye R; Månsson K; Sundström C; Riggare S; Andersson G; Lindefors N; Svenningsson P; Kaldo V
Article: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY. 2020;88(4):311-321

Predicting treatment failure in regular care Internet-Delivered Cognitive Behavior Therapy for depression and anxiety using only weekly symptom measures.

Forsell E; Isacsson N; Blom K; Jernelöv S; Ben Abdesslem F; Lindefors N; Boman M; Kaldo V
Article: JOURNAL OF ATTENTION DISORDERS. 2020;24(6):904-917

Group Treatment for Adults With ADHD Based on a Novel Combination of Cognitive and Dialectical Behavior Interventions: A Feasibility Study.

Nasri B; Castenfors M; Fredlund P; Ginsberg Y; Lindefors N; Kaldo V
Article: COGNITIVE BEHAVIOUR THERAPY. 2019;48(4):300-310

Exposure-based cognitive behavior therapy for atopic dermatitis: an open trial.

Hedman-Lagerlöf E; Bergman A; Lindefors N; Bradley M
Article: TRANSLATIONAL PSYCHIATRY. 2019;9(1):150

A genome-wide association meta-analysis of prognostic outcomes following cognitive behavioural therapy in individuals with anxiety and depressive disorders.

Rayner C; Coleman JRI; Purves KL; Hodsoll J; Goldsmith K; Alpers GW; Andersson E; Arolt V; Boberg J; Bögels S; Creswell C; Cooper P; Curtis C; Deckert J; Domschke K; El Alaoui S; Fehm L; Fydrich T; Gerlach AL; Grocholewski A; Hahlweg K; Hamm A; Hedman E; Heiervang ER; Hudson JL; Jöhren P; Keers R; Kircher T; Lang T; Lavebratt C; Lee S-H; Lester KJ; Lindefors N; Margraf J; Nauta M; Pané-Farré CA; Pauli P; Rapee RM; Reif A; Rief W; Roberts S; Schalling M; Schneider S; Silverman WK; Ströhle A; Teismann T; Thastum M; Wannemüller A; Weber H; Wittchen H-U; Wolf C; Rück C; Breen G; Eley TC
Article: CLINICAL PSYCHOLOGY & PSYCHOTHERAPY. 2019;26(3):298-308

The effects of component-specific treatment compliance in individually tailored internet-based treatment.

Kraepelien M; Blom K; Lindefors N; Johansson R; Kaldo V
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2019;176(4):315-323

Proof of Concept for an Adaptive Treatment Strategy to Prevent Failures in Internet-Delivered CBT: A Single-Blind Randomized Clinical Trial With Insomnia Patients.

Forsell E; Jernelöv S; Blom K; Kraepelien M; Svanborg C; Andersson G; Lindefors N; Kaldo V
Journal article: MOLECULAR PSYCHIATRY. 2019;24(4):484-490

Genetics of response to cognitive behavior therapy in adults with major depression: a preliminary report.

Andersson E; Crowley JJ; Lindefors N; Ljótsson B; Hedman-Lagerlöf E; Boberg J; El Alaoui S; Karlsson R; Lu Y; Mattheisen M; Kähler AK; Svanborg C; Mataix-Cols D; Mattsson S; Forsell E; Kaldo V; Schalling M; Lavebratt C; Sullivan PF; Rück C
Article: MOL NEUROPSYCHIATRY. 2019;4(4):196-203

Exercise Reduces Salivary Morning Cortisol Levels in Patients with Depression.

Rahman MS; Zhao X; Liu JJ; Torres EQ; Tibert B; Kumar P; Kaldo V; Lindefors N; Forsell Y; Lavebratt C
Article: LAKARTIDNINGEN. 2018;115:E9ES

[A Swedish example of integrated perinatal mental health care].

Blomdahl Wetterholm M; Bendix M; Pettersson K; Lindefors N
Article: BJPSYCH OPEN. 2018;4(4):282-284

Comparing individually tailored to disorder-specific internet-based cognitive-behavioural therapy: benchmarking study.

Kraepelien M; Forsell E; Karin E; Johansson R; Lindefors N; Kaldo V
Article: BJPSYCH OPEN. 2018;4(4):265-273

Cost-effectiveness of internet-based cognitive-behavioural therapy and physical exercise for depression.

Kraepelien M; Mattsson S; Hedman-Lagerlöf E; Petersson IF; Forsell Y; Lindefors N; Kaldo V
Article: OCCUPATIONAL AND ENVIRONMENTAL MEDICINE. 2018;75(1):52-58

Effects of internet-based cognitive behavioural therapy and physical exercise on sick leave and employment in primary care patients with depression: two subgroup analyses.

Kaldo V; Lundin A; Hallgren M; Kraepelien M; Strid C; Ekblom Ö; Lavebratt C; Lindefors N; Öjehagen A; Forsell Y
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2017;267:15-21

Associations between cognition and serotonin receptor 1B binding in patients with major depressive disorder - A pilot study.

Tangen Ä; Borg J; Tiger M; Varnäs K; Sorjonen K; Lindefors N; Halldin C; Lundberg J
Article: BMJ OPEN. 2017;7(9):e017053

Does internet-based cognitive behaviour therapy reduce healthcare costs and resource use in treatment of social anxiety disorder? A cost-minimisation analysis conducted alongside a randomised controlled trial.

El Alaoui S; Hedman-Lagerlöf E; Ljótsson B; Lindefors N
Article: SLEEP. 2017;40(8):zsx108

Three-Year Follow-Up Comparing Cognitive Behavioral Therapy for Depression to Cognitive Behavioral Therapy for Insomnia, for Patients With Both Diagnoses.

Blom K; Jernelöv S; Rück C; Lindefors N; Kaldo V
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27(5):462-469

Extrastriatal dopamine D2-receptor availability in social anxiety disorder.

Plavén-Sigray P; Hedman E; Victorsson P; Matheson GJ; Forsberg A; Djurfeldt DR; Rück C; Halldin C; Lindefors N; Cervenka S
Article: COGNITIVE BEHAVIOUR THERAPY. 2017;46(2):114-128

Group acceptance and commitment therapy (ACT) for bipolar disorder and co-existing anxiety - an open pilot study.

Pankowski S; Adler M; Andersson G; Lindefors N; Svanborg C
Article: LAKARTIDNINGEN. 2017;114:D77R

[Internet CBT provides effective treatment].

Lindefors N; El Alaoui S; Svanborg C
Article: BRITISH JOURNAL OF PSYCHIATRY. 2016;209(5):414-420

Exercise and internet-based cognitive-behavioural therapy for depression: multicentre randomised controlled trial with 12-month follow-up.

Hallgren M; Helgadóttir B; Herring MP; Zeebari Z; Lindefors N; Kaldo V; Öjehagen A; Forsell Y
Article: PSYCHIATRY RESEARCH-NEUROIMAGING. 2016;253:36-42

Low serotonin1B receptor binding potential in the anterior cingulate cortex in drug-free patients with recurrent major depressive disorder.

Tiger M; Farde L; Rück C; Varrone A; Forsberg A; Lindefors N; Halldin C; Lundberg J
Article: SLEEP. 2016;39(6):1267-1274

Three-Year Follow-Up of Insomnia and Hypnotics after Controlled Internet Treatment for Insomnia.

Blom K; Jernelöv S; Rück C; Lindefors N; Kaldo V
Article: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2016;4:51-60

Facilitating and hindering factors in Internet-delivered treatment for insomnia and depression.

Blom K; Jernelöv S; Lindefors N; Kaldo V
Article: PLOS ONE. 2016;11(10):e0165389

Combining Time-Driven Activity-Based Costing with Clinical Outcome in Cost-Effectiveness Analysis to Measure Value in Treatment of Depression.

El Alaoui S; Lindefors N
Article: PLOS ONE. 2016;11(9):e0161191

Predicting Outcome in Internet-Based Cognitive Behaviour Therapy for Major Depression: A Large Cohort Study of Adult Patients in Routine Psychiatric Care.

El Alaoui S; Ljótsson B; Hedman E; Svanborg C; Kaldo V; Lindefors N
Article: CLINICAL PSYCHOLOGY & PSYCHOTHERAPY. 2015;22(6):722-732

Testing the Mediating Effects of Obsessive Beliefs in Internet-Based Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder: Results from a Randomized Controlled Trial.

Andersson E; Ljótsson B; Hedman E; Hesser H; Enander J; Kaldo V; Andersson G; Lindefors N; Rück C
Article: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY. 2015;83(5):902-914

Effectiveness of Internet-based cognitive-behavior therapy for social anxiety disorder in clinical psychiatry.

El Alaoui S; Hedman E; Kaldo V; Hesser H; Kraepelien M; Andersson E; Rück C; Andersson G; Ljótsson B; Lindefors N
Article: JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY. 2015;35(5):535-543

Long-Term Treatment Outcome in Adult Male Prisoners With Attention-Deficit/Hyperactivity Disorder: Three-Year Naturalistic Follow-Up of a 52-Week Methylphenidate Trial.

Ginsberg Y; Långström N; Larsson H; Lindefors N
Article: BRITISH JOURNAL OF PSYCHIATRY. 2015;207(3):227-234

Physical exercise and internet-based cognitive-behavioural therapy in the treatment of depression: randomised controlled trial.

Hallgren M; Kraepelien M; Öjehagen A; Lindefors N; Zeebari Z; Kaldo V; Forsell Y
Article: BEHAVIOUR RESEARCH AND THERAPY. 2015;71:90-100

Guided internet cognitive behavioral therapy for insomnia compared to a control treatment - A randomized trial.

Kaldo V; Jernelöv S; Blom K; Ljótsson B; Brodin M; Jörgensen M; Kraepelien M; Rück C; Lindefors N
Article: BEHAVIOUR RESEARCH AND THERAPY. 2015;70:47-55

Internet-vs. group-delivered cognitive behavior therapy for insomnia: A randomized controlled non-inferiority trial.

Blom K; Tarkian Tillgren H; Wiklund T; Danlycke E; Forssén M; Söderström A; Johansson R; Hesser H; Jernelöv S; Lindefors N; Andersson G; Kaldo V
Article: JAMA PSYCHIATRY. 2015;72(7):659-667

D-Cycloserine vs Placebo as Adjunct to Cognitive Behavioral Therapy for Obsessive-Compulsive Disorder and Interaction With Antidepressants: A Randomized Clinical Trial.

Andersson E; Hedman E; Enander J; Radu Djurfeldt D; Ljótsson B; Cervenka S; Isung J; Svanborg C; Mataix-Cols D; Kaldo V; Andersson G; Lindefors N; Rück C
Article: BMJ OPEN. 2015;5(6):e007902

Long-term effectiveness and outcome predictors of therapist-guided internet-based cognitive-behavioural therapy for social anxiety disorder in routine psychiatric care.

El Alaoui S; Hedman E; Ljótsson B; Lindefors N
Article: JOURNAL OF ANXIETY DISORDERS. 2015;31:32-37

Psychometric properties of Internet-administered measures of health anxiety: an investigation of the Health Anxiety Inventory, the Illness Attitude Scales, and the Whiteley Index.

Hedman E; Ljótsson B; Andersson E; Andersson G; Lindefors N; Rück C; Axelsson E; Lekander M
Article: SLEEP. 2015;38(2):267-277

Internet treatment addressing either insomnia or depression, for patients with both diagnoses: a randomized trial.

Blom K; Jernelöv S; Kraepelien M; Bergdahl MO; Jungmarker K; Ankartjärn L; Lindefors N; Kaldo V
Article: PLOS ONE. 2015;10(4):e0124258

Predictors of Symptomatic Change and Adherence in Internet-Based Cognitive Behaviour Therapy for Social Anxiety Disorder in Routine Psychiatric Care.

El Alaoui S; Ljótsson B; Hedman E; Kaldo V; Andersson E; Rück C; Andersson G; Lindefors N
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2015;4:47-53

Cost-effectiveness of internet-based cognitive behavior therapy for obsessive-compulsive disorder: results from a randomized controlled trial

Andersson E; Hedman E; Ljotsson B; Wikstrom M; Elveling E; Lindefors N; Andersson G; Kaldo V; Ruck C
Article: PLOS ONE. 2015;10(4):e0123412

Optimal cut-off points on the health anxiety inventory, illness attitude scales and whiteley index to identify severe health anxiety.

Hedman E; Lekander M; Ljótsson B; Lindefors N; Rück C; Andersson G; Andersson E
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2015;4:1-7

Predictors and moderators of Internet-based cognitive behavior therapy for obsessive-compulsive disorder: Results from a randomized trial

Andersson E; Ljotsson B; Hedman E; Enander J; Kaldo V; Andersson G; Lindefors N; Ruck C
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2015;4:14-19

Cost-effectiveness of an internet-based booster program for patients with obsessive-compulsive disorder: Results from a randomized controlled trial

Andersson E; Ljotsson B; Hedman E; Mattson S; Enander J; Andersson G; Kaldo V; Lindefors N; Ruck C
Article: PSYCHOLOGICAL MEDICINE. 2014;44(13):2877-2887

Long-term efficacy of Internet-based cognitive behavior therapy for obsessive-compulsive disorder with or without booster: a randomized controlled trial.

Andersson E; Steneby S; Karlsson K; Ljótsson B; Hedman E; Enander J; Kaldo V; Andersson G; Lindefors N; Rück C
Article: PSYCHIATRY RESEARCH. 2014;223(2):164-170

Reduced 5-HT(1B) receptor binding in the dorsal brain stem after cognitive behavioural therapy of major depressive disorder.

Tiger M; Rück C; Forsberg A; Varrone A; Lindefors N; Halldin C; Farde L; Lundberg J
Article: BEHAVIOUR RESEARCH AND THERAPY. 2014;59:20-29

Clinical effectiveness and cost-effectiveness of Internet- vs. group-based cognitive behavior therapy for social anxiety disorder: 4-year follow-up of a randomized trial.

Hedman E; El Alaoui S; Lindefors N; Andersson E; Rück C; Ghaderi A; Kaldo V; Lekander M; Andersson G; Ljótsson B
Article: BEHAVIOUR RESEARCH AND THERAPY. 2014;54:22-29

Sudden gains in internet-based cognitive behaviour therapy for severe health anxiety.

Hedman E; Lekander M; Ljótsson B; Lindefors N; Rück C; Hofmann SG; Andersson E; Andersson G; Schulz SM
Article: JOURNAL OF AFFECTIVE DISORDERS. 2014;155:49-58

Effectiveness of Internet-based cognitive behaviour therapy for depression in routine psychiatric care.

Hedman E; Ljótsson B; Kaldo V; Hesser H; El Alaoui S; Kraepelien M; Andersson E; Rück C; Svanborg C; Andersson G; Lindefors N
Article: PLOS ONE. 2014;9(6):e100614

Using early change to predict outcome in cognitive behaviour therapy: exploring timeframe, calculation method, and differences of disorder-specific versus general measures.

Schibbye P; Ghaderi A; Ljótsson B; Hedman E; Lindefors N; Rück C; Kaldo V
Article: PLOS ONE. 2014;9(8):e104615

Effects of baseline problematic alcohol and drug use on internet-based cognitive behavioral therapy outcomes for depression, panic disorder and social anxiety disorder.

Gajecki M; Berman AH; Sinadinovic K; Andersson C; Ljótsson B; Hedman E; Rück C; Lindefors N
Article: PLOS ONE. 2014;9(12):e113871

Personality change following internet-based cognitive behavior therapy for severe health anxiety.

Hedman E; Andersson G; Lindefors N; Gustavsson P; Lekander M; Rück C; Andersson E; Ljótsson B
Article: JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY. 2013;81(6):1113-1126

Mechanisms of change in an exposure-based treatment for irritable bowel syndrome.

Ljótsson B; Hesser H; Andersson E; Lindfors P; Hursti T; Rück C; Lindefors N; Andersson G; Hedman E
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2013;128(6):457-467

Effectiveness of internet-based cognitive behaviour therapy for panic disorder in routine psychiatric care.

Hedman E; Ljótsson B; Rück C; Bergström J; Andersson G; Kaldo V; Jansson L; Andersson E; Andersson E; Blom K; El Alaoui S; Falk L; Ivarsson J; Nasri B; Rydh S; Lindefors N
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2013;15(10):e229-138

Telephone versus internet administration of self-report measures of social anxiety, depressive symptoms, and insomnia: psychometric evaluation of a method to reduce the impact of missing data.

Hedman E; Ljótsson B; Blom K; El Alaoui S; Kraepelien M; Rück C; Andersson G; Svanborg C; Lindefors N; Kaldo V
Article: BEHAVIOUR RESEARCH AND THERAPY. 2013;51(10):711-717

Predictors of outcome in Internet-based cognitive behavior therapy for severe health anxiety.

Hedman E; Lindefors N; Andersson G; Andersson E; Lekander M; Rück C; Ljótsson B
Article: PSYCHOLOGICAL MEDICINE. 2013;43(2):363-374

Cost-effectiveness and long-term effectiveness of internet-based cognitive behaviour therapy for severe health anxiety.

Hedman E; Andersson E; Lindefors N; Andersson G; Rück C; Ljótsson B
Article: PLOS ONE. 2013;8(11):e79015

Genetic polymorphisms in monoamine systems and outcome of cognitive behavior therapy for social anxiety disorder.

Andersson E; Rück C; Lavebratt C; Hedman E; Schalling M; Lindefors N; Eriksson E; Carlbring P; Andersson G; Furmark T
Article: COGNITIVE BEHAVIOUR THERAPY. 2013;42(4):303-314

Internet-delivered CBT for children with specific phobia: a pilot study.

Vigerland S; Thulin U; Ljótsson B; Svirsky L; Ost L-G; Lindefors N; Andersson G; Serlachius E
Article: PLOS ONE. 2013;8(11):e79024

Predictors and moderators of internet- and group-based cognitive behaviour therapy for panic disorder.

El Alaoui S; Hedman E; Ljótsson B; Bergström J; Andersson E; Rück C; Andersson G; Lindefors N
Article: PLOS ONE. 2013;8(10):e77752

Mediators in internet-based cognitive behavior therapy for severe health anxiety.

Hedman E; Andersson E; Andersson G; Lindefors N; Lekander M; Rück C; Ljótsson B
Article: EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE. 2012;262(8):705-724

Long-term functional outcome in adult prison inmates with ADHD receiving OROS-methylphenidate.

Ginsberg Y; Hirvikoski T; Grann M; Lindefors N
Article: PSYCHOLOGICAL MEDICINE. 2012;42(10):2193-2203

Internet-based cognitive behaviour therapy for obsessive-compulsive disorder: a randomized controlled trial.

Andersson E; Enander J; Andrén P; Hedman E; Ljótsson B; Hursti T; Bergström J; Kaldo V; Lindefors N; Andersson G; Rück C
Article: JOURNAL OF OBSESSIVE-COMPULSIVE AND RELATED DISORDERS. 2012;1(4):325-330

Internet administration of the Dimensional Obsessive-Compulsive Scale: a psychometric evaluation

Enander J; Andersson E; Kaldo V; Lindefors N; Andersson G; Ruck C
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2012;126(2):126-136

Clinical and genetic outcome determinants of Internet- and group-based cognitive behavior therapy for social anxiety disorder.

Hedman E; Andersson E; Ljótsson B; Andersson G; Andersson E; Schalling M; Lindefors N; Rück C
Article: TRANSLATIONAL PSYCHIATRY. 2012;2(5):e120

Changes in dopamine D2-receptor binding are associated to symptom reduction after psychotherapy in social anxiety disorder.

Cervenka S; Hedman E; Ikoma Y; Djurfeldt DR; Rück C; Halldin C; Lindefors N
Article: BRITISH JOURNAL OF PSYCHIATRY. 2012;200(1):68-73

Methylphenidate treatment of adult male prison inmates with attention-deficit hyperactivity disorder: randomised double-blind placebo-controlled trial with open-label extension.

Ginsberg Y; Lindefors N
Article: BEHAVIOUR RESEARCH AND THERAPY. 2011;49(11):729-736

Cost-effectiveness of Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: results from a randomized controlled trial.

Hedman E; Andersson E; Ljótsson B; Andersson G; Rück C; Lindefors N
Article: BMC GASTROENTEROLOGY. 2011;11:110

Acceptability, effectiveness, and cost-effectiveness of internet-based exposure treatment for irritable bowel syndrome in a clinical sample: a randomized controlled trial.

Ljótsson B; Andersson G; Andersson E; Hedman E; Lindfors P; Andréewitch S; Rück C; Lindefors N
Article: BMC PSYCHIATRY. 2011;11:125

Internet-based cognitive behavior therapy for obsessive compulsive disorder: a pilot study.

Andersson E; Ljótsson B; Hedman E; Kaldo V; Paxling B; Andersson G; Lindefors N; Rück C
Article: AMERICAN JOURNAL OF GASTROENTEROLOGY. 2011;106(8):1481-1491

Internet-delivered exposure-based treatment vs. stress management for irritable bowel syndrome: a randomized trial.

Ljótsson B; Hedman E; Andersson E; Hesser H; Lindfors P; Hursti T; Rydh S; Rück C; Lindefors N; Andersson G
Article: JOURNAL OF MEDICAL INTERNET RESEARCH. 2011;13(2):e39

A 5-Year follow-up of internet-based cognitive behavior therapy for social anxiety disorder.

Hedman E; Furmark T; Carlbring P; Ljótsson B; Rück C; Lindefors N; Andersson G
Article: BMC PUBLIC HEALTH. 2011;11:215

Cost-effectiveness of internet-based cognitive behavior therapy for irritable bowel syndrome: results from a randomized controlled trial.

Andersson E; Ljótsson B; Smit F; Paxling B; Hedman E; Lindefors N; Andersson G; Rück C
Article: LAKARTIDNINGEN. 2011;108(14):785

[Anxiety is our heritage and we should administer it well].

Lindefors N; Andersson G
Article: PLOS ONE. 2011;6(3):e18001

Internet-based cognitive behavior therapy vs. cognitive behavioral group therapy for social anxiety disorder: a randomized controlled non-inferiority trial.

Hedman E; Andersson G; Ljótsson B; Andersson E; Rück C; Mörtberg E; Lindefors N
Article: BRITISH JOURNAL OF PSYCHIATRY. 2011;198(3):230-236

Internet-based cognitive-behavioural therapy for severe health anxiety: randomised controlled trial.

Hedman E; Andersson G; Andersson E; Ljótsson B; Rück C; Asmundson GJG; Lindefors N
Article: BEHAVIOUR RESEARCH AND THERAPY. 2011;49(1):58-61

Long-term follow-up of internet-delivered exposure and mindfulness based treatment for irritable bowel syndrome.

Ljótsson B; Hedman E; Lindfors P; Hursti T; Lindefors N; Andersson G; Rück C
Article: BMC PSYCHIATRY. 2010;10:112

Attention Deficit Hyperactivity Disorder (ADHD) among longer-term prison inmates is a prevalent, persistent and disabling disorder.

Ginsberg Y; Hirvikoski T; Lindefors N
Article: BMC PSYCHIATRY. 2010;10:99

The COMTval158met polymorphism is associated with symptom relief during exposure-based cognitive-behavioral treatment in panic disorder.

Lonsdorf TB; Rück C; Bergström J; Andersson G; Ohman A; Lindefors N; Schalling M
Article: JOURNAL OF BEHAVIOR THERAPY AND EXPERIMENTAL PSYCHIATRY. 2010;41(3):185-190

Exposure and mindfulness based therapy for irritable bowel syndrome--an open pilot study.

Ljótsson B; Andréewitch S; Hedman E; Rück C; Andersson G; Lindefors N
Article: BMC PSYCHIATRY. 2010;10:54

Internet-versus group-administered cognitive behaviour therapy for panic disorder in a psychiatric setting: a randomised trial.

Bergström J; Andersson G; Ljótsson B; Rück C; Andréewitch S; Karlsson A; Carlbring P; Andersson E; Lindefors N
Article: COMPUTERS IN HUMAN BEHAVIOR. 2010;26(4):736-740

Internet administration of self-report measures commonly used in research on social anxiety disorder: A psychometric evaluation

Hedman E; Ljotsson B; Ruck C; Furmark T; Carlbring P; Lindefors N; Andersson G
Article: BEHAVIOUR RESEARCH AND THERAPY. 2010;48(6):531-539

Internet-delivered exposure and mindfulness based therapy for irritable bowel syndrome--a randomized controlled trial.

Ljótsson B; Falk L; Vesterlund AW; Hedman E; Lindfors P; Rück C; Hursti T; Andréewitch S; Jansson L; Lindefors N; Andersson G
Article: COGNITIVE BEHAVIOUR THERAPY. 2010;39(4):239-250

Effectiveness and cost offset analysis of group CBT for hypochondriasis delivered in a psychiatric setting: an open trial.

Hedman E; Ljótsson B; Andersson E; Rück C; Andersson G; Lindefors N
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2009;166(6):675-682

Cognitive effects of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: a randomized, open-label clinical trial (EUFEST).

Davidson M; Galderisi S; Weiser M; Werbeloff N; Fleischhacker WW; Keefe RS; Boter H; Keet IPM; Prelipceanu D; Rybakowski JK; Libiger J; Hummer M; Dollfus S; López-Ibor JJ; Hranov LG; Gaebel W; Peuskens J; Lindefors N; Riecher-Rössler A; Kahn RS
Article: NORDIC JOURNAL OF PSYCHIATRY. 2009;63(1):44-50

An open study of the effectiveness of Internet treatment for panic disorder delivered in a psychiatric setting.

Bergström J; Andersson G; Karlsson A; Andréewitch S; Rück C; Carlbring P; Lindefors N
Article: PSYCHOPHARMACOLOGY. 2008;197(2):295-307

Emotional perception modulated by an opioid and a cholecystokinin agonist.

Gospic K; Gunnarsson T; Fransson P; Ingvar M; Lindefors N; Petrovic P
Article: LANCET. 2008;371(9618):1085-1097

Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial.

Kahn RS; Fleischhacker WW; Boter H; Davidson M; Vergouwe Y; Keet IPM; Gheorghe MD; Rybakowski JK; Galderisi S; Libiger J; Hummer M; Dollfus S; López-Ibor JJ; Hranov LG; Gaebel W; Peuskens J; Lindefors N; Riecher-Rössler A; Grobbee DE; EUFEST study group
Article: BRAIN RESEARCH. 2006;1104(1):175-182

Overlapping regional distribution of CCK and TPPII mRNAs in Cynomolgus monkey brain and correlated levels in human cerebral cortex (BA 10).

Radu D; Tomkinson B; Zachrisson O; Weber G; de Belleroche J; Hirsch S; Lindefors N
Article: CURRENT OPINION IN PSYCHIATRY. 2005;18(1):73-77

The use of the Internet in the treatment of anxiety disorders.

Andersson G; Bergström J; Carlbring P; Lindefors N
Article: PSYCHOPHARMACOLOGY. 2003;166(2):139-145

Pentagastrin test for anxiety--psychophysiology and personality.

Radu D; Ahlin A; Svanborg P; Lindefors N
Article: PSYCHOPHARMACOLOGY. 2002;161(4):396-403

Anxiogenic effects of the CCK(B) agonist pentagastrin in humans and dose-dependent increase in plasma C-peptide levels.

Radu D; Ahlin A; Svanborg P; Lindefors N
Article: BRAIN RESEARCH. 2001;908(2):197-203

Delayed stress-induced increase in tissue level of cholecystokinin in rat prefrontal cortex: modulation by microdialysis probe implantation and systemic ketamine.

Radu D; Brodin E; Weber G; Lindefors N
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2000;10(5):355-363

Effects of antipsychotic drugs on cholecystokinin and preprotachykinin (substance P) mRNA expression in the rat hippocampal formation.

Zachrisson O; Nomikos GG; Marcus MM; Svensson TH; Lindefors N
Article: NEUROREPORT. 1999;10(16):3265-3268

Cholecystokinin CCK(B) receptor mRNA isoforms: expression in schizophrenic brains.

Zachrisson O; de Belleroche J; Wendt KR; Hirsch S; Lindefors N
Article: BRAIN RESEARCH. 1998;60(2):291-295

A tachykinin NK1 receptor antagonist, CP-122,721-1, attenuates kainic acid-induced seizure activity.

Zachrisson O; Lindefors N; Brené S
Article: BRAIN RESEARCH. 1997;48(2):413-416

GABA release and GAD67 mRNA expression in rat hippocampus following entorhinal cortex activation.

Falkenberg T; Lindefors N; O'Connor WT; Zachrisson O; Camilli F; Ungerstedt U
Article: BRAIN RESEARCH. 1997;759(2):205-212

Differential effects of single and repeated ketamine administration on dopamine, serotonin and GABA transmission in rat medial prefrontal cortex.

Lindefors N; Barati S; O'Connor WT
Article: BRAIN RESEARCH. 1997;45(2):275-282

Effect of chronic antipsychotic drug treatment on preprosomatostatin and preprotachykinin A mRNA levels in the medial prefrontal cortex, the nucleus accumbens and the caudate putamen of the rat.

Marcus MM; Nomikos GG; Malmerfelt A; Zachrisson O; Lindefors N; Svensson TH
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1997;319(2-3):191-195

Decreased levels of preprotachykinin-A and tachykinin NK1 receptor mRNA in specific region of the rat striatum after electroconvulsive stimuli.

Zachrisson O; Mathé AA; Lindefors N
Article: BRAIN RESEARCH. 1996;43(1-2):347-350

Effects of chronic lithium and electroconvulsive stimuli on cholecystokinin mRNA expression in the rat brain.

Zachrisson O; Mathé AA; Lindefors N
Article: BRAIN RESEARCH. 1996;42(2):317-327

Glutamate release correlates with brain-derived neurotrophic factor and trkB mRNA expression in the CA1 region of rat hippocampus.

Falkenberg T; Lindefors N; Camilli F; Metsis M; Ungerstedt U
Article: BRAIN RESEARCH. 1996;36(1):169-173

Neuronal coexistence of trkB and glutamic acid decarboxylase67 mRNAs in rat hippocampus.

Zachrisson O; Falkenberg T; Lindefors N
Article: PSYCHOPHARMACOLOGY. 1995;120(3):333-340

Electroconvulsive shock increases dopamine D1 and D2 receptor mRNA in the nucleus accumbens of the rat.

Smith S; Lindefors N; Hurd Y; Sharp T
Article: NEUROSCIENCE LETTERS. 1995;194(1-2):89-92

Region-specific effects of chronic lithium administration on neuropeptide Y and somatostatin mRNA expression in the rat brain.

Zachrisson O; Mathé AA; Stenfors C; Lindefors N
Article: NEUROSCIENCE. 1995;67(1):37-48

Distribution of messenger RNAs for D1 dopamine receptors and DARPP-32 in striatum and cerebral cortex of the cynomolgus monkey: relationship to D1 dopamine receptors.

Brené S; Hall H; Lindefors N; Karlsson P; Halldin C; Sedvall G
Article: BRAIN RESEARCH. 1995;31(1-2):71-85

Limbic effects of repeated electroconvulsive stimulation on neuropeptide Y and somatostatin mRNA expression in the rat brain.

Zachrisson O; Mathé AA; Stenfors C; Lindefors N
Article: NEUROSCIENCE. 1995;65(3):661-670

Spatiotemporal selective effects on brain-derived neurotrophic factor and trkB messenger RNA in rat hippocampus by electroconvulsive shock.

Lindefors N; Brodin E; Metsis M
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Letter: JAMA DERMATOLOGY. 2022;158(11):1325-1327

Optimized User Experience, Efficiency, and Resource Use in Online Self-Management of Atopic Dermatitis.

Kern D; Ljótsson B; Lönndahl L; Hedman-Lagerlöf E; Bradley M; Lindefors N; Kraepelien M
Corrigendum: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2022;29:100550

Corrigendum to "The effect of user interface on treatment engagement in a self-guided digital problem-solving intervention: A randomized controlled trial" [Internet Interv. 26 (2021) 1-10/100448].

Hentati A; Forsell E; Ljótsson B; Kaldo V; Lindefors N; Kraepelien M
Review: JAMA PSYCHIATRY. 2021;78(4):361-371

Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis.

Karyotaki E; Efthimiou O; Miguel C; Bermpohl FMG; Furukawa TA; Cuijpers P; Individual Patient Data Meta-Analyses for Depressi; Riper H; Patel V; Mira A; Gemmil AW; Yeung AS; Lange A; Williams AD; Mackinnon A; Geraedts A; van Straten A; Meyer B; Björkelund C; Knaevelsrud C; Beevers CG; Botella C; Strunk DR; Mohr DC; Ebert DD; Kessler D; Richards D; Littlewood E; Forsell E; Feng F; Wang F; Andersson G; Hadjistavropoulos H; Christensen H; Ezawa ID; Choi I; Rosso IM; Klein JP; Shumake J; Garcia-Campayo J; Milgrom J; Smith J; Montero-Marin J; Newby JM; Bretón-López J; Schneider J; Vernmark K; Bücker L; Sheeber LB; Warmerdam L; Farrer L; Heinrich M; Huibers MJH; Kivi M; Kraepelien M; Forand NR; Pugh N; Lindefors N; Lintvedt O; Zagorscak P; Carlbring P; Phillips R; Johansson R; Kessler RC; Brabyn S; Perini S; Rauch SL; Gilbody S; Moritz S; Berger T; Pop V; Kaldo V; Spek V; Forsell Y
Published conference paper: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2019;18:100263

Individually tailored internet treatment in routine care: A feasibility study.

Kraepelien M; Svanborg C; Lallerstedt L; Sennerstam V; Lindefors N; Kaldo V
Review: CANADIAN JOURNAL OF PSYCHIATRY-REVUE CANADIENNE DE PSYCHIATRIE. 2019;64(7):465-470

Internet Interventions for Adults with Anxiety and Mood Disorders: A Narrative Umbrella Review of Recent Meta-Analyses.

Andersson G; Carlbring P; Titov N; Lindefors N
Review: INTERNET INTERVENTIONS-THE APPLICATION OF INFORMATION TECHNOLOGY IN MENTAL AND BEHAVIOURAL HEALTH. 2018;13:108-115

ICBT in routine care: A descriptive analysis of successful clinics in five countries.

Titov N; Dear B; Nielssen O; Staples L; Hadjistavropoulos H; Nugent M; Adlam K; Nordgreen T; Bruvik KH; Hovland A; Repål A; Mathiasen K; Kraepelien M; Blom K; Svanborg C; Lindefors N; Kaldo V
Review: CLINICAL PSYCHOLOGY REVIEW. 2018;63:80-92

Do guided internet-based interventions result in clinically relevant changes for patients with depression? An individual participant data meta-analysis.

Karyotaki E; Ebert DD; Donkin L; Riper H; Twisk J; Burger S; Rozental A; Lange A; Williams AD; Zarski AC; Geraedts A; van Straten A; Kleiboer A; Meyer B; Ünlü Ince BB; Buntrock C; Lehr D; Snoek FJ; Andrews G; Andersson G; Choi I; Ruwaard J; Klein JP; Newby JM; Schröder J; Laferton JAC; Van Bastelaar K; Imamura K; Vernmark K; Boß L; Sheeber LB; Kivi M; Berking M; Titov N; Carlbring P; Johansson R; Kenter R; Perini S; Moritz S; Nobis S; Berger T; Kaldo V; Forsell Y; Lindefors N; Kraepelien M; Björkelund C; Kawakami N; Cuijpers P
Review: EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH. 2012;12(6):745-764

Cognitive behavior therapy via the Internet: a systematic review of applications, clinical efficacy and cost-effectiveness.

Hedman E; Ljótsson B; Lindefors N
Corrigendum: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2011;35(1):312

The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism (vol 33, pg 1479, 2009)

Lonsdorf TB; Ruck C; Bergstrom J; Andersson G; Ohman A; Schalling M; Lindefors N
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2009;33(8):1479-1483

The symptomatic profile of panic disorder is shaped by the 5-HTTLPR polymorphism.

Lonsdorf TB; Rück C; Bergström J; Andersson G; Ohman A; Schalling M; Lindefors N
Meeting abstract: EUROPEAN PSYCHIATRY. 2008;23:S355-S356

Effectiveness of internet treatment for panic disorder delivered in a psychiatric setting

Bergstroem J; Ljotsson B; Andersson G; Andreewitch S; Ruck C; Carlbring P; Lindefors N
Meeting abstract: EUROPEAN PSYCHIATRY. 2007;22:S61-S62

Can we benefit from internet to increase accessibility to an effective non-pharmacological treatment for major depression and anxiety disorders?

Lindefors N
Meeting abstract: SCHIZOPHRENIA RESEARCH. 2000;41(1):254-255

Cholecystokinin in CCK_B receptor mRNA isoforms:: Expression in post-mortem monkey and human brain -: Alterations following schizophrenia

Radu D; Zachrisson O; de Belleroche J; Wendt KR; Hirsh S; Lindefors N
Meeting abstract: SCHIZOPHRENIA RESEARCH. 1998;29(1-2):199-200

Evidence for an alteration in the balance between dopamine and serotonin transmission in the medial prefrontal cortex of the conscious rat following repeated ketamine administration

O'Connor WT; Lindefors N
Meeting abstract: SCHIZOPHRENIA RESEARCH. 1998;29(1-2):168-169

CCK receptors in the brain as targets for new antipsychotic drugs

Lindefors N

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