mona_esbjornsson_pp.jpg

mona Esbjörnsson

Anknuten till Forskning

Om mig

Forskare och lärare vid Institutionen för laboratoriemedicin, avdelningen för Klinisk fysiologi, Karolinska Universitetssjukhuset (HS).

Biomedicinsk analytiker år 1980

Disputerade år 2000

Post Doc 2001-2005 (50%) vid Inst för Medicin, enheten för Reumatoligi KU, Solan

Docent i Fysiologi år 2011

 

Forskningsbeskrivning

1. Jacobs I., Esbjörnsson M., Sylvén C., Holm I. & Jansson E. Sprint training effect on muscle myoglobin, enzymes, fibre type and blood lactate. Med Sci Sport Exerc, 19:368-374, 1987

2. Dahlström M., Esbjörnsson M., Jansson E. & Kaijser L. Muscle fibre characteristics in female dancers during an active and an inactive period. Int J Sport Med, 8:84-87, 1987

3. Jansson E., Esbjörnsson M., Holm I. & Jacobs I. Increase in the proportion of fast-twitch muscle fibres by sprint training in males. Acta Physiol Scand, 140:359-363, 1990.

4. Eiken O., Sundberg C-J., Esbjörnsson M., Nygren A & Kaijser L. Effects of ischeamic training on force development and fibre-type composition in human skeletal muscle. Clin Physiol, 11:41-49, 1991

5. Kaijser L., Sundberg C-J., Eiken O., Nygren A., Esbjörnsson M., Sylvén C., & Jansson E. Muscle oxidative capacity and work performance after training under local leg ischemia. J Appl Physiol, 69:785-787, 1990

6. Hildebrandt I. L., Sylvén C., Esbjörnsson M., Hellström K. & Jansson E. Does chronic hypoxaemia induce transformations of fibre types? Acta Physiol Scand, 141:435-439, 1991

*7. Esbjörnsson M., Sylvén C., Holm I. & Jansson E. Fast twitch fibres may predict anaerobic performance in both females and males. Int J Sport Med, 14:257-263, 1993

8. Esbjörnsson M., Y. Hellsten-Westing, P. Balsom, B. Sjödin & E. Jansson. Muscle fibre type changes with sprint training: Effect of training pattern. Acta Physiol Scand, 149: 245-246, 1993

9. Esbjörnsson M., Sundberg C-J., Eiken O., Jansson E., Nygren A. & Kaijser L. Muscle fiber types and enzyme activities after training with local ischemia in man. Acta Physiol Scand, 148:233-241, 1993

10. Clyne N., Esbjörnsson M., Jansson E., Jogestrand T., Lins L. & Pehrsson S. Effects of renal failure on skeletal muscle. Nephron, 63:395-399, 1993

*11. Esbjörnsson Liljedahl M., Holm I., Sylvén C. & Jansson E. Different responses of the skeletal muscle following sprint training in males and females. Eur J Appl Physiol, 74:375-383, 1996

12. Harridge S.D.R., Bottinelli R, Canepari M, Pellegrino M.A, Reggiani C, Esbjörnsson M & Saltin B. Whole-muscle and single-fibre contractile properties and myosin heavy chain isoforms in humans. Plügers Arch- Eur J Physiol, 432:913-920, 1996

13. Dahlström M., Esbjörnsson Liljedahl M., Gierup M., Kaijser L. & Jansson E. High proportion of type I muscle fibres in tigh of young dancers. Acta Physiol Scand, 160:49-55, 1997

14. Harridge S.D.R, Bottinelli R., Canepari M., Pellegrino M.A. Reggiani C., Esbjörnsson M., Balsom P. D. & Saltin B. Sprint training, in vitro and in vivo muscle function and myosin heavy chain expression. J Appl Physiol, 84:442-449, 1998

*15. Esbjörnsson Liljedahl M., Sundberg C. J., Norman B. & Jansson E. Metabolic response in type I and II muscle fibers during a 30-s cycle sprint in men and females. J Appl Physiol, 87:1326-1332, 1999

*16. Esbjörnsson Liljedahl M. & Jansson E. Sex difference in plasma ammonia but not in muscle inosine monophosphate accumulation following sprint exercise in humans. Eur J Appl Physiol, 79:404-408, 1999

17. Nygren A. T, Sundberg C. J., Göranson H., Esbjörnsson Liljedahl M., Janson E. & Kaijser L. Effects of ischaemic training on human skeletal muscle dimensions as measured by magnetic resonance imaging. Eur J Appl Physiol, 82:137-141, 2000

18. Cederholm T., Sylvén C., Esbjörnsson M. & Jansson E. Insulin treatment increases skeletal muscle fibre area in patients with diabetes mellitus type 2. Clin Physiol, 20:354-359, 2000

*19. Esbjörnsson-Liljedahl M., Bodin K. & Jansson E. Smaller muscle ATP reduction in women than in men by repeated bouts of sprint exercise. J Appl Physiol, 93:1075-1083, 2002

20. Wiik A., Glenmark B., Ekman M., Esbjörnsson-Liljedahl M., Johansson O., Bodin K., Enmark E. & Jansson E. Oestrogen receptor ß is expressed in adult human skeletal muscle both at the mRNA and protein level. Acta Physiol Scand, 179:381-387, 2003

21. Wiik A., Gustafsson T., Esbjörnsson M., Johansson O., Ekman M., Sundberg C.J., Jansson E. Expression of oestrogen receptor alpha and b is higher in skeletal muscle of highly endurance-trained than of moderately active men. Acta Physiol Scand, 184:105-112, 2005

22. Wiik A., Ekman M., Morgan G., Johansson O., Jansson E. & Esbjörnsson M. Oestrogen receptor ß present in both skeletal muscle fibres and endothelia cells within human skeletal muscle tissue. Histochemistry and Cell Biology, 124:161-5, 2005

23. Esbjörnsson M., Bülow J., Norman B., Simonsen L., Nowak J., Rooyackers O., Kaijser L. & Jansson E. Adipose tissue extracts plasma ammonia after sprint exercise in women and men. J Appl Physiol, 101:1576-80, 2006

24. Dastmalchi M., Alexanderson H., Loell I., Ståhlberg M., Borg K., Lundberg I. E. & Esbjörnsson M. The Effect of Physical Training on the Proportion of Slow-Twitch Type I Muscle Fibers, a Novel Nonimmune-Mediated Mechanism for Muscle Impairment in Polymyositis or Dermatomyositis. Arthritis Care & Research, 57:1303-1310, 2007

25. Barbasso Helmers S., Dastmalchi M., Alexanderson H., Nennesmo I., Esbjörnsson M., Lindvall B. & Lundberg I. E. Limited effects of high-dose intravenous immunoglobulin (IVIg) treatment on molecular expression in muscle tissue of patients with inflammatory myopathies. Annals of the Rheumatic Diseases, Ann Rheum Dis, 66:1276-83, 2007

26. Fischer H., Esbjornsson M., Sabina R. L., Stromberg A., Peyrard-Janvid M. & Norman B. AMP deaminase deficiency is associated with lower sprint cycling performance in healthy subjects. J Appl Physiol, 103:315-22, 2007

27. Alexanderson H., Dastmalchi M., Esbjörnsson M., Stenström C. H. & Lundberg I. E. Benefits of intensive resistive exercise in patients with stable and inactive polymyositis or dermatomyositis. Arthritis Rheum, 57:768-77, 2007

28. Wiik A., Ekman M., Johansson O., Jansson E. & Esbjörnsson M. Expression of both oestrogen receptor alpha and beta protein in human skeletal muscle tissue. Histochem Cell Biol, 131: 181-9, 2009

29. Norman B., Esbjörnsson M., Rundqvist H., Osterlund T., von Walden F. & Tesch P. A. Strength, power, fiber types and mRNA expression in trained men and women with different ACTN3 R577X genotypes. J Appl Physiol, 106:959-65, 2009

30. Esbjörnsson M., Norman B., Suchdev S., Viru M., Lindhgren A. & Jansson E. Greater growth hormone and insulin respons in women than in men during repeated bouts of sprint exercise. Acta Phys Scand, 197; 107-115, 2009

 31. Esbjörnsson M., Rooyackers O., Norman B., Rundqvist H. C., Nowak J., Bülow J., Simonsen L. & Jansson E. Gender specific levels of plasma and muscle amino acids before and after repeated bouts of sprint exercise. Scand J Med Sci Sports. 22:399-409, 2012

32. Nader G. A., Dastmalchi M., Alexanderson H., Grundtman C., Germapudi R., Esbjörnsson M., Wang Z., Rönnelid J., Hoffman E. P., Nagaraju K. & Lundberg I. E. A longitudinal, integrated clinical, histological and mRNA profiling study of resistance exercise in myositis. Molmed, 16 (11-12); 455-46, 2010

33. Loell I., Barbasso Helmers S., Dastmalchi M., Alexanderson H., Alemo Munters L., Nennesmo I., Lindroos E., Borg K., Lundberg I. E & Esbjörnsson M. Higher proportion of fatst-twitch (type II) muscle fibres in idiopatic inflammatory myopathies – evident in chronic but not in untreated newly diagnosed patients. Clin Physiol Funct Imaging, 31; 18-25, 2011

34. Esbjörnsson M., Rundqvist HC., Mascher H., Österlund T., Rooyackers O., Blomstrand E. & Jansson E. Sprint exercise enhances skeletal muscle p70S6k phosphorylation and more so in females than in males. Acta Physiol. 205:411-22, 2012

35. Rundqvist H. C., Lilja M. R., Rooyackers O., Odrzywol K, Murray J. T., *Esbjörnsson M. and *Jansson E. Nutrient ingestion increased mtor signaling, but not hvps34 activity in human skeletal muscle after sprint exercise. * indicate equal contribution. Physiological Reports 2013

36. Alemo Munters L, Dastmalchi M, Katz A, Esbjornsson M, Loell I, Hanna B, Liden M, Westerblad H, Lundberg I, Alexanderson H. Arthritis Res Ther. 2013 Aug 13;15(4):R83. PMID:23941324

37. Alemo Munters L, Dastmalchi M, Andgren V, Emilson C, Bergegård J, Regardt M, Johansson A, Tholander IO, Hanna B, Lidén M, Esbjörnsson M, Alexanderson H.Arthritis Care Res (Hoboken). 2013 Jul 16. doi: 10.1002/acr.22068. PMID:23861241

38. Norman B., Esbjörnsson M., Rundqvist H., Österlund T., Sundberg C. J., Lindholm M, Glenmark B., and Jansson E. ACTN3 genotype and modulation of skeletal muscle response to exercise in human subjects. J Appl Physiol 116:1197-203, 2014

39. Li Alemo Munters*, Ingela Loell*, Elena Ossipova*,  Joan Raouf,  Maryam Dastmalchi, Eva Lindroos, Yi-Wen Chen, Mona Esbjörnsson, Marina Korotkova, , Helene Alexanderson, Kanneboyina Nagaraju, , Leslie Crofford, Per-Johan Jakobsson*,  Ingrid E Lundberg*. *Shared first and last authors. Endurance Exercise Improves Molecular Pathways of Aerobic Metabolism in Patients with Myositis. Arthritis & Rheumatology. Submitted.