Johan Högberg

Johan Högberg


Ongoing research projects:
- Gender differences in carcinogenesis (supported by Formas)
- Low-dose genotoxic effects of crystalline silica particles (supported by AFA).


Recent selected publications:

Approaches for the setting of occupational exposure limits (OELs) for carcinogens.

Högberg J, Järnberg J.Crit Rev Toxicol. 2023 Dec;53(3):131-167. doi: 10.1080/10408444.2023.2218887. Epub 2023 Jun 27.PMID: 37366107 Review

ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline Silica Particles.

Zheng H, Stenius U, Högberg J.Cancers (Basel). 2023 Jan 30;15(3):865. doi: 10.3390/cancers15030865.PMID: 36765823.

Application of Text Mining in Risk Assessment of Chemical Mixtures: A Case Study of Polycyclic Aromatic Hydrocarbons (PAHs).

Ali I, Dreij K, Baker S, Högberg J, Korhonen A, Stenius U.Environ Health Perspect. 2021 Jun;129(6):67008. doi: 10.1289/EHP6702. Epub 2021 Jun 24.PMID: 34165340.

Crystalline silica particles induce DNA damage in respiratory epithelium by ATX secretion and Rac1 activation.

Wu R, Högberg J, Adner M, Stenius U, Zheng H.Biochem Biophys Res Commun. 2021 Apr 9;548:91-97. doi: 10.1016/j.bbrc.2021.02.020. Epub 2021 Feb 23.PMID: 33636640.

Crystalline silica particles cause rapid NLRP3-dependent mitochondrial depolarization and DNA damage in airway epithelial cells.

Wu R, Högberg J, Adner M, Ramos-Ramírez P, Stenius U, Zheng H.Part Fibre Toxicol. 2020 Aug 10;17(1):39. doi: 10.1186/s12989-020-00370-2.PMID: 32778128.