Joel Nordin

Journal article: EXTRACELLULAR VESICLE. 2025;5:100065

Identification of robust and abundant reference transcripts for EV mRNA cargo normalization

Zickler AM; Grochowski R; Görgens A; Bäcklin E; Kordes M; Löhr J-M; Nordin JZ; Andaloussi SE; Hagey DW

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2025;14(2):e70042

Extracellular Histones as Exosome Membrane Proteins Regulated by Cell Stress

Singh B; Fredriksson Sundbom M; Muthukrishnan U; Natarajan B; Stransky S; Gorgens A; Nordin JZ; Wiklander OPB; Sandblad L; Sidoli S; El Andaloussi S; Haney M; Gilthorpe JD

Journal article: NATURE REVIEWS BIOENGINEERING. 2025;:1-16

Genetic tools for investigating the life cycle of extracellular vesicles

Zheng W; Roudi S; Zhou H; Lara Corona M; van Niel G; Nordin JZ; EL Andaloussi S

Article: ADVANCED SCIENCE. 2024;11(42):e2407619

Novel Endogenous Engineering Platform for Robust Loading and Delivery of Functional mRNA by Extracellular Vesicles

Zickler AM; Liang X; Gupta D; Mamand DR; De Luca M; Corso G; Errichelli L; Hean J; Sen T; Elsharkasy OM; Kamei N; Niu Z; Zhou G; Zhou H; Roudi S; Wiklander OPB; Gorgens A; Nordin JZ; Castilla-Llorente V; EL Andaloussi S

Article: NATURE BIOMEDICAL ENGINEERING. 2024;8(11):1453-1468

Antibody-displaying extracellular vesicles for targeted cancer therapy

Wiklander OPB; Mamand DR; Mohammad DK; Zheng W; Jawad Wiklander R; Sych T; Zickler AM; Liang X; Sharma H; Lavado A; Bost J; Roudi S; Corso G; Lennaard AJ; Abedi-Valugerdi M; Maeger I; Alici E; Sezgin E; Nordin JZ; Gupta D; Goergens A; EL Andaloussi S

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2024;13(7):e12471

Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting

Mamand DR; Bazaz S; Mohammad DK; Liang X; Pavlova S; Mim C; Gabrielsson S; Nordin JZ; Wiklander OPB; Abedi-Valugerdi M; EL-Andaloussi S

Article: NATURE COMMUNICATIONS. 2023;14(1):4734

Identification of scaffold proteins for improved endogenous engineering of extracellular vesicles

Zheng W; Raedler J; Sork H; Niu Z; Roudi S; Bost JPP; Goergens A; Zhao Y; Mamand DRR; Liang X; Wiklander OPB; Lehto T; Gupta D; Nordin JZZ; EL Andaloussi S

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2022;11(7):e12248

Extracellular vesicles engineered to bind albumin demonstrate extended circulation time and lymph node accumulation in mouse models

Liang X; Niu Z; Galli V; Howe N; Zhao Y; Wiklander OPB; Zheng W; Wiklander RJ; Corso G; Davies C; Hean J; Kyriakopoulou E; Mamand DR; Amin R; Nordin JZ; Gupta D; Andaloussi SEL

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2021;10(12):e12142

Extracellular vesicles are the primary source of blood-borne tumour-derived mutant KRAS DNA early in pancreatic cancer

Hagey DW; Kordes M; Gorgens A; Mowoe MO; Nordin JZ; Moro CF; Lohr J-M; El Andaloussi S

Article: NATURE BIOMEDICAL ENGINEERING. 2021;5(9):1084-1098

Amelioration of systemic inflammation via the display of two different decoy protein receptors on extracellular vesicles.

Gupta D; Wiklander OPB; Görgens A; Conceição M; Corso G; Liang X; Seow Y; Balusu S; Feldin U; Bostancioglu B; Jawad R; Mamand DR; Lee YXF; Hean J; Mäger I; Roberts TC; Gustafsson M; Mohammad DK; Sork H; Backlund A; Lundin P; de Fougerolles A; Smith CIE; Wood MJA; Vandenbroucke RE; Nordin JZ; El-Andaloussi SAll authors

Article: CELLS. 2021;10(6):1543

Profiling of Extracellular Small RNAs Highlights a Strong Bias towards Non-Vesicular Secretion

Sork H; Conceicao M; Corso G; Nordin J; Lee YXF; Krjutskov K; Orzechowski Westholm J; Vader P; Pauwels M; Vandenbroucke RE; Wood MJA; EL Andaloussi S; Mager I

Article: PHARMACEUTICS. 2021;13(6):878

Efficient Peptide-Mediated In Vitro Delivery of Cas9 RNP

Gustafsson O; Radler J; Roudi S; Lehto T; Hallbrink M; Lehto T; Gupta D; EL Andaloussi S; Nordin JZ

Article: FRONTIERS IN PHYSIOLOGY. 2021;12:698166

Lipidomic Analyses Reveal Specific Alterations of Phosphatidylcholine in Dystrophic Mdx Muscle

Valentine WJ; Mostafa SA; Tokuoka SM; Hamano F; Inagaki NF; Nordin JZ; Motohashi N; Kita Y; Aoki Y; Shimizu T; Shindou H

Article: FRONTIERS IN PHYSIOLOGY. 2021;12:689179

Fine Tuning of Phosphorothioate Inclusion in 2′-O-Methyl Oligonucleotides Contributes to Specific Cell Targeting for Splice-Switching Modulation

Aoki Y; Rocha CSJ; Lehto T; Miyatake S; Johansson H; Hashimoto Y; Nordin JZ; Mager I; Aoki M; Graham M; Sathyaprakash C; Roberts TC; Wood MJA; Behlke MA; El Andaloussi S

Article: BIOMATERIALS. 2021;266:120435

Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle

Conceica M; Forcina L; Wiklander OPB; Gupta D; Nordin JZ; Vrellaku B; McClorey G; Mager I; Gorgens A; Lundin P; Musaro A; Wood MJA; Andaloussi SEL; Roberts TC

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2020;9(1):1800222

Quantification of extracellular vesicles in vitro and in vivo using sensitive bioluminescence imaging

Gupta D; Liang X; Pavlova S; Wiklander OPB; Corso G; Zhao Y; Saher O; Bost J; Zickler AM; Piffko A; Maire CL; Ricklefs FL; Gustafsson O; Llorente VC; Gustafsson MO; Bostancioglu RB; Mamand DR; Hagey DW; Goergens A; Nordin JZ; EL Andaloussi S

Article: JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. 2020;(159)

Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides.

Nordin JZ; Mizobe Y; Nakamura H; Komaki H; Takeda S; Aoki Y

Article: ADVANCED FUNCTIONAL MATERIALS. 2019;29(48)

Supramolecular Assembly of Aminoethylene-Lipopeptide PMO Conjugates into RNA Splice-Switching Nanomicelles

Kuhn J; Klein PM; Al Danaf N; Nordin JZ; Reinhard S; Loy DM; Hoehn M; El Andaloussi S; Lamb DC; Wagner E; Aoki Y; Lehto T; Laechelt U

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2019;8(1):1663043

Systematic characterization of extracellular vesicles sorting domains and quantification at the single molecule - single vesicle level by fluorescence correlation spectroscopy and single particle imaging

Corso G; Heusermann W; Trojer D; Goergens A; Steib E; Voshol J; Graff A; Genoud C; Lee Y; Hean J; Nordin JZ; Wiklander OPB; El Andaloussi S; Meisner-Kober N

Article: METHODS IN MOLECULAR BIOLOGY. 2019;1953:287-299

Tangential Flow Filtration with or Without Subsequent Bind-Elute Size Exclusion Chromatography for Purification of Extracellular Vesicles.

Nordin JZ; Bostancioglu RB; Corso G; El Andaloussi S

Article: SCIENTIFIC REPORTS. 2018;8(1):10813

Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome

Sork H; Corso G; Krjutskov K; Johansson HJ; Nordin JZ; Wiklander OPB; Lee YXF; Westholm JO; Lehtio J; Wood MJA; Mager I; El Andaloussi S

Article: FRONTIERS IN IMMUNOLOGY. 2018;9:1326

Systematic Methodological Evaluation of a Multiplex Bead-Based Flow Cytometry Assay for Detection of Extracellular Vesicle Surface Signatures

Wiklander OPB; Bostancioglu RB; Welsh JA; Zickler AM; Murke F; Corso G; Felldin U; Hagey DW; Evertsson B; Liang X-M; Gustafsson MO; Mohammad DK; Wiek C; Hanenberg H; Bremer M; Gupta D; Bjornstedt M; Giebel B; Nordin JZ; Jones JC; EL Andaloussi S; Goergens A

Article: SCIENTIFIC REPORTS. 2017;7(1):11561

Reproducible and scalable purification of extracellular vesicles using combined bind-elute and size exclusion chromatography

Corso G; Mager I; Lee Y; Gorgens A; Bultema J; Giebel B; Wood MJA; Nordin JZ; Andaloussi SEL

Article: METHODS IN MOLECULAR BIOLOGY. 2017;1545:197-204

Preparation and Isolation of siRNA-Loaded Extracellular Vesicles.

Vader P; Mäger I; Lee Y; Nordin JZ; Andaloussi SEL; Wood MJA

Article: DIABETOLOGIA. 2016;59(5):1049-1058

Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice

Jalabert A; Vial G; Guay C; Wiklander OPB; Nordin JZ; Aswad H; Forterre A; Meugnier E; Pesenti S; Regazzi R; Danty-Berger E; Ducreux S; Vidal H; El-Andaloussi S; Rieusset J; Rome S

Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2016;5(3):e290

Lipid-based Transfection Reagents Exhibit Cryo-induced Increase in Transfection Efficiency

Sork H; Nordin JZ; Turunen JJ; Wiklander OPB; Bestas B; Zaghloul EM; Margus H; Padari K; Duru AD; Corso G; Bost J; Vader P; Pooga M; Smith CIE; Wood MJA; Schiffelers RM; Hallbrink M; Andaloussi SEL

Article: STEM CELLS TRANSLATIONAL MEDICINE. 2015;4(10):1199-1213

In Vivo Effects of Mesenchymal Stromal Cells in Two Patients With Severe Acute Respiratory Distress Syndrome

Simonson OE; Mougiakakos D; Heldring N; Bassi G; Johansson HJ; Dalen M; Jitschin R; Rodin S; Corbascio M; El Andaloussi S; Wiklander OPB; Nordin JZ; Skog J; Romain C; Koestler T; Hellgren-Johansson L; Schiller P; Joachimsson P-O; Haegglund H; Mattsson M; Lentio J; Faridani OR; Sandberg R; Korsgren O; Krampera M; Weiss DJ; Grinnemo K-H; Le Blanc K

Article: NANO LETTERS. 2015;15(7):4364-4373

Self-Assembly into Nanoparticles Is Essential for Receptor Mediated Uptake of Therapeutic Antisense Oligonucleotides

Ezzat K; Aoki Y; Koo T; McClorey G; Benner L; Coenen-Stass A; O'Donovan L; Lehto T; Garcia-Guerra A; Nordin J; Saleh AF; Behlke M; Morris J; Goyenvalle A; Dugovic B; Leumann C; Gordon S; Gait MJ; El-Andaloussi S; Wood MJA

Article: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE. 2015;11(4):879-883

Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties

Nordin JZ; Lee Y; Vader P; Maeger I; Johansson HJ; Heusermann W; Wiklander OPB; Hallbrink M; Seow Y; Bultema JJ; Gilthorpe J; Davies T; Fairchild PJ; Gabrielsson S; Meisner-Kober NC; Lehtio J; Smith CIE; Wood MJA; Andaloussi SEL

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26316

Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting

Wiklander OPB; Nordin JZ; O'Loughlin A; Gustafsson Y; Corso G; Maeger I; Vader P; Lee Y; Sork H; Seow Y; Heldring N; Alvarez-Erviti L; Smith CIE; Le Blanc K; Macchiarini P; Jungebluth P; Wood MJA; EL Andaloussi S

Article: JOURNAL OF EXTRACELLULAR VESICLES. 2015;4:26883

Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles

Li J; Lee Y; Johansson HJ; Maeger I; Vader P; Nordin JZ; Wiklander OPB; Lehtio J; Wood MJA; Andaloussi SEL

Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2014;3(11):e212

Correlating In Vitro Splice Switching Activity With Systemic In Vivo Delivery Using Novel ZEN-modified Oligonucleotides

Hammond SM; McClorey G; Nordin JZ; Godfrey C; Stenler S; Lennox KA; Smith CIE; Jacobi AM; Varela MA; Lee Y; Behlke MA; Wood MJA; Andaloussi SEL

Article: MOVEMENT DISORDERS. 2014;29(12):1476-1485

Systemic Exosomal siRNA Delivery Reduced Alpha-Synuclein Aggregates in Brains of Transgenic Mice

Cooper JM; Wiklander PBO; Nordin JZ; Al-Shawi R; Wood MJ; Vithlani M; Schapira AHV; Simons JP; El-Andaloussi S; Alvarez-Erviti L

Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(9):4067-4081

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

Bestas B; Moreno PMD; Blomberg KEM; Mohammad DK; Saleh AF; Sutlu T; Nordin JZ; Guterstam P; Gustafsson MO; Kharazi S; Piatosa B; Roberts TC; Behlke MA; Wood MJA; Gait MJ; Lundin KE; El Andaloussi S; Mansson R; Berglof A; Wengel J; Smith CIE

Article: MOLECULAR THERAPY NUCLEIC ACIDS. 2014;3(1):e140

Micro-minicircle Gene Therapy: Implications of Size on Fermentation, Complexation, Shearing Resistance, and Expression

Stenler S; Wiklander OPB; Badal-Tejedor M; Turunen J; Nordin JZ; Hallengard D; Wahren B; Andaloussi SEL; Rutland MW; Smith CIE; Lundin KE; Blomberg P

Article: BRITISH JOURNAL OF SURGERY. 2014;101(2):100-108

Diagnostic value of abdominal drainage in individual risk assessment of pancreatic fistula following pancreaticoduodenectomy

Ansorge C; Nordin JZ; Lundell L; Strommer L; Rangelova E; Blomberg J; del Chiaro M; Segersvard R

Journal article: PANCREATOLOGY. 2013;13(3):s82

The diagnostic value of pancreatic amylase analyses from prophylactic abdominal drainage in identifying pancreatic fistula following pancreaticoduodenectomy

Ansorge C; Nordin J; Strömmer L; Lundell L; Rangelova E; Blomberg J; del Chiaro M; Segersvärd R

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