Jan Zedenius

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2025;110(3):693-705

BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer

Xu Y; Gao J; Wang N; Zedenius J; Nilsson I-L; Lui W-O; Xu D; Juhlin CC; Larsson C; Mu N

Article: ENDOCRINE-RELATED CANCER. 2024;31(9):e230061

Genetic variants and down-regulation of CACNA1H in pheochromocytoma

Svahn F; Hose KS; Stenman A; Liu Y; Calissendorff J; Tham E; Vegvari A; Zubarev RA; Wang N; Korah R; Carling T; Zedenius J; Branstrom R; Juhlin CC; Larsson C

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2024;109(7):1733-1744

Prevalence, Molecular Landscape, and Clinical Impact of DICER1 and DGCR8 Mutated Follicular-Patterned Thyroid Nodules

Condello V; Poma AM; Macerola E; Vignali P; Paulsson JO; Zedenius J; Basolo F; Juhlin CC

Article: ENDOCRINE PATHOLOGY. 2024;35(2):122-133

Spatial Transcriptomics in a Case of Follicular Thyroid Carcinoma Reveals Clone-Specific Dysregulation of Genes Regulating Extracellular Matrix in the Invading Front

Condello V; Paulsson JO; Zedenius J; Naesman A; Juhlin CC

Article: BJS OPEN. 2024;8(1):zrad154

Regional variations in the management of primary hyperparathyroidism in Sweden: population-based case-control study

Thorsteinsson D; Granath F; Branstrom R; Koman A; Zedenius J; Nilsson I-L

Article: LANCET REGIONAL HEALTH-EUROPE. 2023;35:100769

Distinguishing between thyroid and parathyroid nodules by ultrasound: a potential game-changer in clinical practice?

Juhlin CC; Zedenius J

Article: ENDOCRINE. 2023;82(3):631-637

Adrenal and periadrenal schwannoma: histological, molecular and clinical characterization of an institutional case series

Stenman A; Falhammar H; Zedenius J; Juhlin CC

Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 2023;71(8):451-458

5hmC Immunohistochemistry: A Predictor of TERT Promoter Mutational Status in Follicular Thyroid Carcinoma?

Hysek M; Hellgren SLL; Condello V; Xu Y; Larsson C; Zedenius J; Juhlin CC

Article: LAKARTIDNINGEN. 2023;120:23045

[Many adrenal incidentalomas are not adequately evaluated - updated guidelines to improve follow-up are presented].

Muth A; Sundin A; Zedenius J

Article: DIAGNOSTIC CYTOPATHOLOGY. 2023;51(6):331-340

Digital droplet PCR TERT promoter mutational screening in fine needle aspiration cytology of thyroid lesions: A highly specific technique for pre-operative identification of high-risk cases

Hysek M; Hellgren LS; Stenman A; Darai-Ramqvist E; Ljung E; Schliemann I; Condello V; Larsson C; Zedenius J; Jatta K; Juhlin CC

Journal article: EJSO. 2023;49(2):e29

Thyroglobulin expression, Ki-67 index, and lymph node ratio in papillary thyroid cancer – new insight into the prognostic assessment of PTC

Lindfors H; Ihre-Lundgren C; Zedenius J; Juhlin CC; Shabo I

Article: SCIENTIFIC REPORTS. 2023;13(1):1070

Thyroglobulin expression, Ki-67 index, and lymph node ratio in the prognostic assessment of papillary thyroid cancer

Lindfors H; Karlsen M; Karlton E; Zedenius J; Larsson C; Ihre Lundgren C; Juhlin CC; Shabo I

Article: ENDOCRINE PATHOLOGY. 2022;33(4):525-527

Papillary Thyroid Carcinoma with Desmoid-Like Fibromatosis: Double Trouble?

Juhlin CC; Hysek M; Stenman A; Zedenius J

Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2022;61(5):140

Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma

Scicluna P; Caramuta S; Kjellin H; Xu C; Froebom R; Akhtar M; Gao J; Shi H; Kjellman M; Almgren M; Hoog A; Zedenius J; Ekstroem TJ; Braenstroem R; Lui W-O; Larsson C

Journal article: HUMAN PATHOLOGY REPORTS. 2022;29:300656

Adrenal cortical adenoma arising in an adreno-hepatic fusion: Case report and literature review of a potential diagnostic pitfall

Stenman A; Shabo I; Zedenius J; Juhlin CC

Article: ENDOCRINE PATHOLOGY. 2022;33(2):231-242

Prognostic Utility of the Ki-67 Labeling Index in Follicular Thyroid Tumors: a 20-Year Experience from a Tertiary Thyroid Center

Hellgren LS; Stenman A; Paulsson JO; Hoog A; Larsson C; Zedenius J; Juhlin CC

Article: BIOMEDICINE & PHARMACOTHERAPY. 2022;149:112796

Synergistic effects of telomerase reverse transcriptase and regulator of telomere elongation helicase 1 on aggressiveness and outcomes in adrenocortical carcinoma

Yuan H; Wu Y; Wang J; Qin X; Huang Y; Yan L; Fana Y; Zedenius J; Juhlin CC; Larsson C; Lui W-O; Xu D

Article: THYROID RESEARCH. 2022;15(1):1

Synchronous lateral lymph node metastases from papillary and follicular thyroid carcinoma: case report and review of the literature

Stenman A; Kjellman M; Zedenius J; Juhlin CC

Article: DIAGNOSTIC CYTOPATHOLOGY. 2022;50(2):75-83

Cyto-morphological features of parathyroid lesions: Fine-needle aspiration cytology series from an endocrine tumor referral center

Steen S; Hysek M; Zedenius J; Falhammar H; Juhlin CC

Article: CANCERS. 2021;13(24):6340

Pan-Genomic Sequencing Reveals Actionable CDKN2A/2B Deletions and Kataegis in Anaplastic Thyroid Carcinoma

Stenman A; Yang M; Paulsson JO; Zedenius J; Paulsson K; Juhlin CC

Article: PATHOLOGY. 2021;53(7):852-859

Institutional characterisation of water clear cell parathyroid adenoma: a rare entity often unrecognised by TC-99m-sestamibi scintigraphy

Juhlin CC; Nilsson I-L; Falhammar H; Zedenius J

Article: ENDOCRINE PATHOLOGY. 2021;32(4):513-516

TERT Promoter Mutated Follicular Thyroid Carcinomas Exhibit a Distinct microRNA Expressional Profile with Potential Implications for Tumor Progression

Paulsson JO; Zedenius J; Juhlin CC

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2021;106(11):3265-3282

Whole-genome Sequencing of Follicular Thyroid Carcinomas Reveal Recurrent Mutations in MicroRNA Processing Subunit DGCR8

Paulsson JO; Rafati N; DiLorenzo S; Chen Y; Haglund F; Zedenius J; Juhlin CC

Article: HISTOPATHOLOGY. 2021;79(4):661-666

Macrofollicular variant follicular thyroid tumors are DICER1 mutated and exhibit distinct histological features

Juhlin CC; Stenman A; Zedenius J

Journal article: HISTOPATHOLOGY. 2021;79(4):0i

Cover Image

Article: SCANDINAVIAN JOURNAL OF SURGERY. 2021;110(3):322-328

A Single Parathyroid Hormone Measurement Two Hours after a Thyroidectomy Reliably Predicts Permanent Hypoparathyroidism

Palmhag D; Brydolf J; Zedenius J; Branstrom R; Nilsson I-L

Article: THYROID RESEARCH. 2021;14(1):19

Development of metastatic poorly differentiated thyroid cancer from a sub-centimeter papillary thyroid carcinoma in a young patient with a germline MET mutation - association or random chance?

Johansson K; Stenman A; Paulsson JO; Wang N; Ihre-Lundgren C; Zedenius J; Juhlin CC

Article: WORLD JOURNAL OF SURGERY. 2021;45(7):2155-2164

The Clinical Significance of Lymph Node Ratio and Ki-67 Expression in Papillary Thyroid Cancer

Lindfors H; Ihre Lundgren C; Zedenius J; Juhlin CC; Shabo I

Article: HEAD AND NECK PATHOLOGY. 2021;15(2):628-637

Perithyroidal Salivary Gland Acinic Cell Carcinoma: Morphological and Molecular Attributes of a Unique Lesion

Juhlin CC; Asa SL; Jatta K; Rodsari HN; Shabo I; Haglund F; Delahunt B; Samaratunga H; Egevad L; Hoog A; Zedenius J

Article: EJSO. 2021;47(6):1364-1369

Metastasis to the thyroid gland: Characterization and survival of an institutional series spanning 28 years

Stergianos S; Juhlin CC; Zedenius J; Calissendorff J; Falhammar H

Article: JOURNAL OF CLINICAL PATHOLOGY. 2021;75(10):jclinpath-2021-207631-662

Nuclear-specific accumulation of telomerase reverse transcriptase (TERT) mRNA in TERT promoter mutated follicular thyroid tumours visualised by in situ hybridisation: a possible clinical screening tool?

Hellgren LS; Olsson A; Kaufeldt A; Paulsson JO; Hysek M; Stenman A; Zedenius J; Larsson C; Hoog A; Juhlin CC

Article: ENDOCRINE-RELATED CANCER. 2021;28(5):337-351

Pan-genomic characterization of high-risk pediatric papillary thyroid carcinoma

Stenman A; Backman S; Johansson K; Paulsson JO; Stalberg P; Zedenius J; Juhlin CC

Article: JOURNAL OF MOLECULAR DIAGNOSTICS. 2021;23(2):212-222

Spatial Distribution Patterns of Clinically Relevant TERT Promoter Mutations in Follicular Thyroid Tumors of Uncertain Malignant Potential Advantages of the Digital Droplet PCR Technique

Hysek M; Jatta K; Hellgren LS; Stenman A; Larsson C; Zedenius J; Juhlin CC

Article: BRAIN PATHOLOGY. 2021;31(1):61-69

TERTpromoter mutations in primary and secondary WHO grade III meningioma

Maier AD; Stenman A; Svahn F; Mirian C; Bartek JJ; Juhler M; Zedenius J; Broholm H; Mathiesen T

Article: FRONTIERS IN ENDOCRINOLOGY. 2021;12:724766

Parathyroid Adenoma With Respiratory-Like Epithelium: Case Report of a Potential Mimic With Unknown Etiology

Juhlin CC; Zedenius J

Article: ENDOCRINE PATHOLOGY. 2020;31(4):401-410

Clinical Routine Application of the Second-generation Neuroendocrine Markers ISL1, INSM1, and Secretagogin in Neuroendocrine Neoplasia: Staining Outcomes and Potential Clues for Determining Tumor Origin

Juhlin CC; Zedenius J; Hoog A

Article: BREAST CANCER RESEARCH AND TREATMENT. 2020;183(3):669-675

Sarcoma of the breast: breast cancer history as etiologic and prognostic factor-A population-based case-control study

Karlsson F; Granath F; Smedby KE; Zedenius J; Branstrom R; Nilsson I-L

Article: ENDOCRINE PATHOLOGY. 2020;31(2):156-165

Lipoadenoma of the Parathyroid Gland: Characterization of an Institutional Series Spanning 28 Years

Juhlin CC; Falhammar H; Zedenius J; Nilsson I-L; Hoog A

Article: SCANDINAVIAN JOURNAL OF SURGERY. 2020;109(2):133-142

Impact of immunohistochemistry on the diagnosis and management of primary aldosteronism: An important tool for improved patient follow-up

Volpe C; Hamberger B; Zedenius J; Juhlin CC

Article: ENDOCRINE-RELATED CANCER. 2020;27(5):295-308

GABPA-dependent down-regulation of DICER1 in follicular thyroid tumours

Paulsson JO; Wang N; Gao J; Stenman A; Zedenius J; Mu N; Lui W-O; Larsson C; Juhlin CC

Article: ENDOCRINE PATHOLOGY. 2020;31(1):77-83

Metastatic Anaplastic Thyroid Carcinoma in Complete Remission: Morphological, Molecular, and Clinical Work-Up of a Rare Case

Stenman A; Hellgren LS; Jatta K; Hysek M; Zemmler M; Altena R; Nilsson I-L; Branstrom R; Zedenius J; Juhlin CC

Article: JOURNAL OF PATHOLOGY. 2020;250(2):183-194

Whole-genome sequencing of synchronous thyroid carcinomas identifies aberrant DNA repair in thyroid cancer dedifferentiation

Paulsson JO; Backman S; Wang N; Stenman A; Crona J; Thutkawkorapin J; Ghaderi M; Tham E; Stalberg P; Zedenius J; Juhlin CC

Article: EPIGENETICS. 2019;14(12):1224-1233

Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations

Fotouhi O; Ghaderi M; Wang N; Zedenius J; Kjellman M; Xu D; Juhlin CC; Larsson C

Article: DIAGNOSTIC PATHOLOGY. 2019;14(1):127

Signet ring cell variant of follicular thyroid carcinoma: Report of two cases with focus on morphological, expressional and genetic characteristics

Hysek M; Jatta K; Stenman A; Darai-Ramqvist E; Zedenius J; Hoog A; Juhlin CC

Article: SURGERY. 2019;166(5):901-906

Retrospective application of the pathologic tumor-node-metastasis classification system for pheochromocytoma and abdominal paraganglioma in a well characterized cohort with long-term follow-up

Stenman A; Zedenius J; Juhlin CC

Article: ONCOGENE. 2019;38(43):6881-6897

Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors

Fotouhi O; Kjellin H; Juhlin CC; Pan Y; Vesterlund M; Ghaderi M; Yousef A; Andersson-Sand H; Kharaziha P; Caramuta S; Kjellman M; Zedenius J; Larsson C; Orre LM

Article: CANCERS. 2019;11(10):E1443-1443

Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of Metastatic Disease

Hysek M; Paulsson JO; Jatta K; Shabo I; Stenman A; Hoog A; Larsson C; Zedenius J; Juhlin CC

Article: ENDOCRINE PATHOLOGY. 2019;30(3):246-248

TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up

Stenman A; Hysek M; Jatta K; Branstrom R; Darai-Ramqvist E; Paulsson JO; Wang N; Larsson C; Zedenius J; Juhlin CC

Article: LAKARTIDNINGEN. 2019;116:FHM3

[Endocrine tumours in Stockholm - increasing general incidence].

Juhlin CC; Stenman A; Zedenius J

Article: AMERICAN JOURNAL OF SURGICAL PATHOLOGY. 2019;43(3):409-421

Molecular Profiling of Pheochromocytoma and Abdominal Paraganglioma Stratified by the PASS Algorithm Reveals Chromogranin B as Associated With Histologic Prediction of Malignant Behavior

Stenman A; Svahn F; Hojjat-Farsangi M; Zedenius J; Soderkvist P; Gimm O; Larsson C; Juhlin CC

Article: VIRCHOWS ARCHIV. 2018;473(5):639-643

TERT promoter mutational screening as a tool to predict malignant behaviour in follicular thyroid tumours-three examples from the clinical routine

Hysek M; Paulsson JO; Wang N; Jatta K; Lindh C; Fuentes-Martinez N; Shabo I; Zedenius J; Juhlin CC

Article: NEUROENDOCRINOLOGY LETTERS. 2018;39(4):305-309

Regional differences in somatostatin receptor 2 (SSTR2) immunoreactivity is coupled to level of bowel invasion in small intestinal neuroendocrine tumors

Fotouhi O; Zedenius J; Hoog A; Juhlin CC

Article: LANGENBECKS ARCHIVES OF SURGERY. 2018;403(6):785-790

Over-diagnosis of potential malignant behavior in MEN 2A-associated pheochromocytomas using the PASS and GAPP algorithms

Stenman A; Zedenius J; Juhlin CC

Article: ENDOCRINE. 2018;61(2):293-302

High Ki-67 index in fine needle aspiration cytology of follicular thyroid tumors is associated with increased risk of carcinoma

Mu N; Juhlin CC; Tani E; Sofiadis A; Reihner E; Zedenius J; Larsson C; Nilsson I-L

Article: BMC ENDOCRINE DISORDERS. 2018;18(1):46

Papillary thyroid carcinoma with pleomorphic tumor giant cells in a pregnant woman - a case report

Paulsson JO; Zedenius J; Juhlin CC

Article: ENDOCRINE-RELATED CANCER. 2018;25(7):723-733

TERT aberrancies: a screening tool for malignancy in follicular thyroid tumours

Paulsson JO; Mu N; Shabo I; Wang N; Zedenius J; Larsson C; Juhlin CC

Article: WORLD JOURNAL OF SURGERY. 2018;42(3):632-638

Recovery of Voice After Reconstruction of the Recurrent Laryngeal Nerve and Adjuvant Nimodipine

Mattsson P; Frostell A; Bjorck G; Persson JKE; Hakim R; Zedenius J; Svensson M

Article: LAKARTIDNINGEN. 2017;114:ETTI

[Finally! A new program for adrenal incidentaloma].

Zedenius J

Article: SURGERY. 2017;162(2):429-436

Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy

Nilsson I-L; Norenstedt S; Zedenius J; Pernow Y; Branstrom R

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2016;101(10):3616-3627

Proteomics Suggests a Role for APC-Survivin in Response to Somatostatin Analog Treatment of Neuroendocrine Tumors

Fotouhi O; Kjellin H; Larsson C; Hashemi J; Barriuso J; Juhlin CC; Lu M; Hoog A; Pastrian LG; Lamarca A; Heredia Soto V; Zedenius J; Mendiola M; Lehtio J; Kjellman M

Article: ENDOCRINE. 2016;53(2):505-511

Minimally invasive follicular thyroid carcinomas: prognostic factors

Stenson G; Nilsson I-L; Mu N; Larsson C; Lundgren CI; Juhlin CC; Hoog A; Zedenius J

Article: ONCOTARGET. 2016;7(16):21332-21346

Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Wang N; Kjellin H; Sofiadis A; Fotouhi O; Juhlin CC; Backdahl M; Zedenius J; Xu D; Lehtio J; Larsson C

Article: SURGERY. 2016;159(1):211-217

FGF23, metabolic risk factors, and blood pressure in patients with primary hyperparathyroidism undergoing parathyroid adenomectomy

Nilsson I-L; Norenstedt S; Granath F; Zedenius J; Pernow Y; Larsson TE

Article: ENDOCRINE-RELATED CANCER. 2015;22(5):735-744

Novel somatic mutations and distinct molecular signature in aldosterone-producing adenomas

Akerstrom T; Willenberg HS; Cupisti K; Ip J; Backman S; Moser A; Maharjan R; Robinson B; Iwen KA; Dralle H; Volpe CD; Backdahl M; Botling J; Stalberg P; Westin G; Walz MK; Lehnert H; Sidhu S; Zedenius J; Bjorklund P; Hellman P

Article: EXPERIMENTAL CELL RESEARCH. 2015;336(1):158-170

Secretome protein signature of human gastrointestinal stromal tumor cells

Berglund E; Dare E; Branca RMM; Akcakaya P; Frobom R; Berggren P-O; Lui W-O; Larsson C; Zedenius J; Orre L; Lehtio J; Kim J; Branstrom R

Article: CLINICAL ENDOCRINOLOGY. 2015;82(5):639-647

Primary aldosteronism: functional histopathology and long-term follow-up after unilateral adrenalectomy

Volpe C; Hamberger B; Hoog A; Mukai K; Calissendorff J; Wahrenberg H; Zedenius J; Thoren M

Article: HUMAN MOLECULAR GENETICS. 2015;24(8):2318-2329

Characterization of the mutational landscape of anaplastic thyroid cancer via whole-exome sequencing

Kunstman JW; Juhlin CC; Goh G; Brown TC; Stenman A; Healy JM; Rubinstein JC; Choi M; Kiss N; Nelson-Williams C; Mane S; Rimm DL; Prasad ML; Hoog A; Zedenius J; Larsson C; Korah R; Lifton RP; Carling T

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2015;172(2):181-187

Aberg V; Norenstedt S; Zedenius J; Saaf M; Nordenstrom J; Pernow Y; Nilsson I-L

Article: PLOS ONE. 2015;10(5):e0126472

Differential Protein Expression Profiles of Cyst Fluid from Papillary Thyroid Carcinoma and Benign Thyroid Lesions

Dinets A; Pernemalm M; Kjellin H; Sviatoha V; Sofiadis A; Juhlin CC; Zedenius J; Larsson C; Lehtio J; Hoog A

Article: CLINICAL CANCER RESEARCH. 2014;20(22):5733-5744

Human Anaplastic Thyroid Carcinoma Cells Are Sensitive to NK Cell-Mediated Lysis via ULBP2/5/6 and Chemoattract NK Cells

Wennerberg E; Pfefferle A; Ekblad L; Yoshimoto Y; Kremer V; Kaminskyy VO; Juhlin CC; Hoog A; Bodin I; Svjatoha V; Larsson C; Zedenius J; Wennerberg J; Lundqvist A

Article: ONCOGENE. 2014;33(42):4978-4984

The age- and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas

Liu T; Wang N; Cao J; Sofiadis A; Dinets A; Zedenius J; Larsson C; Xu D

Article: CANCER. 2014;120(19):2965-2979

TERT Promoter Mutation as an Early Genetic Event Activating Telomerase in Follicular Thyroid Adenoma (FTA) and Atypical FTA

Wang N; Liu T; Sofiadis A; Juhlin CC; Zedenius J; Hoog A; Larsson C; Xu D

Article: EXPERIMENTAL CELL RESEARCH. 2014;326(2):315-325

Functional role of the Ca²⁺-activated Cl^- channel DOG1/TMEM16A in gastrointestinal stromal tumor cells

Berglund E; Akcakaya P; Berglund D; Karlsson F; Vukojevic V; Lee L; Bogdanovic D; Lui W-O; Larsson C; Zedenius J; Frobom R; Branstrom R

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2014;99(8):E1571-E1579

Telomerase-Dependent and Independent Telomere Maintenance and its Clinical Implications in Medullary Thyroid Carcinoma

Wang N; Xu D; Sofiadis A; Hoog A; Vukojevic V; Backdahl M; Zedenius J; Larsson C

Article: EPIGENETICS. 2014;9(7):987-997

Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors An in vivo and in vitro study

Fotouhi O; Fahmideh MA; Kjellman M; Sulaiman L; Hoog A; Zedenius J; Hashemi J; Larsson C

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2014;170(4):583-591

MicroRNA expression patterns associated with hyperfunctioning and non-hyperfunctioning phenotypes in adrenocortical adenomas

Velazquez-Fernandez D; Caramuta S; Ozata DM; Lu M; Hoog A; Backdahl M; Larsson C; Lui W-O; Zedenius J

Article: ANTI-CANCER DRUGS. 2014;25(4):415-422

Intracellular concentration of the tyrosine kinase inhibitor imatinib in gastrointestinal stromal tumor cells

Berglund E; Ubhayasekera SJKA; Karlsson F; Akcakaya P; Aluthgedara W; Ahlen J; Frobom R; Nilsson I-L; Lui W-O; Larsson C; Zedenius J; Bergquist J; Branstrom R

Article: JOURNAL OF BONE AND MINERAL RESEARCH. 2014;29(4):960-967

Vitamin D Supplementation After Parathyroidectomy: Effect on Bone Mineral Density-A Randomized Double-Blind Study

Norenstedt S; Pernow Y; Zedenius J; Nordenstrom J; Saaf M; Granath F; Nilsson I-L

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2013;169(6):795-804

Primary hyperparathyroidism and metabolic risk factors, impact of parathyroidectomy and vitamin D supplementation, and results of a randomized double-blind study

Norenstedt S; Pernow Y; Brismar K; Saaf M; Ekip A; Granath F; Zedenius J; Nilsson I-L

Article: BMC CANCER. 2013;13:505

Copy number alterations in small intestinal neuroendocrine tumors determined by array comparative genomic hybridization

Hashemi J; Fotouhi O; Sulaiman L; Kjellman M; Hoog A; Zedenius J; Larsson C

Article: BRITISH JOURNAL OF SURGERY. 2013;100(11):1505-1514

Outcome after resection and radiofrequency ablation of liver metastases from small intestinal neuroendocrine tumours

Norlen O; Stalberg P; Zedenius J; Hellman P

Article: ENDOCRINE-RELATED CANCER. 2013;20(4):551-564

Clinical and functional impact of TARBP2 over-expression in adrenocortical carcinoma

Caramuta S; Lee L; Ozata DM; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O

Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1229-1238

Evidence for Ca²⁺-regulated ATP release in gastrointestinal stromal tumors

Berglund E; Berglund D; Akcakaya P; Ghaderi M; Dare E; Berggren P-O; Kohler M; Aspinwall CA; Lui W-O; Zedenius J; Larsson C; Branstrom R

Article: JOURNAL OF SURGICAL ONCOLOGY. 2012;106(8):981-986

Anaplastic carcinoma of the thyroid gland: Treatment and outcome over 13 years at one institution

Segerhammar I; Larsson C; Nilsson I-L; Backdahl M; Hoog A; Wallin G; Foukakis T; Zedenius J

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2012;166(6):1049-1060

Clinical, genetic, and immunohistochemical characterization of 70 Ukrainian adult cases with post-Chornobyl papillary thyroid carcinoma

Dinets A; Hulchiy M; Sofiadis A; Ghaderi M; Hoog A; Larsson C; Zedenius J

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2012;166(4):657-667

Proteomic profiling of follicular and papillary thyroid tumors

Sofiadis A; Becker S; Hellman U; Hultin-Rosenberg L; Dinets A; Hulchiy M; Zedenius J; Wallin G; Foukakis T; Hoog A; Auer G; Lehtio J; Larsson C

Journal article: JOURNAL OF CANCER THERAPEUTICS & RESEARCH. 2012;1(1):11

Side-effects from imatinib treatment of advanced GIST–associated with a better outcome

Åhlén J; Westerdahl J; Zedenius J; Bränström R; Larsson C; Nilsson I-L

Article: PLOS ONE. 2012;7(7):e41926

Comprehensive Re-Sequencing of Adrenal Aldosterone Producing Lesions Reveal Three Somatic Mutations near the KCNJ5 Potassium Channel Selectivity Filter

Akerstrom T; Crona J; Verdugo AD; Starker LF; Cupisti K; Willenberg HS; Knoefel WT; Saeger W; Feller A; Ip J; Soon P; Anlauf M; Alesina PF; Schmid KW; Decaussin M; Levillain P; Wangberg B; Peix J-L; Robinson B; Zedenius J; Backdahl M; Caramuta S; Iwen KA; Botling J; Stalberg P; Kraimps J-L; Dralle H; Hellman P; Sidhu S; Westin G; Lehnert H; Walz MK; Akerstrom G; Carling T; Choi M; Lifton RP; Bjorklund P

Article: WORLD JOURNAL OF SURGERY. 2011;35(12):2691-2697

Thyroid Incidentaloma Detected by Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography: Practical Management Algorithm

Nilsson I-L; Arnberg F; Zedenius J; Sundin A

Article: ENDOCRINE-RELATED CANCER. 2011;18(6):643-655

The role of microRNA deregulation in the pathogenesis of adrenocortical carcinoma

Ozata DM; Caramuta S; Velazquez-Fernandez D; Akcakaya P; Xie H; Hoog A; Zedenius J; Backdahl M; Larsson C; Lui W-O

Article: CLINICAL EPIDEMIOLOGY. 2011;3:103-106

Breast cancer associated with primary hyperparathyroidism: a nested case control study.

Norenstedt S; Granath F; Ekbom A; Bergh J; Lambe M; Adolfsson J; Warnberg F; Zedenius J; Nilsson I-L

Article: THYROID. 2010;20(10):1067-1076

Proteomic Study of Thyroid Tumors Reveals Frequent Up-Regulation of the Ca²⁺-Binding Protein S100A6 in Papillary Thyroid Carcinoma

Sofiadis A; Dinets A; Orre LM; Branca RM; Juhlin CC; Foukakis T; Wallin G; Hoog A; Hulchiy M; Zedenius J; Larsson C; Lehtio J

Article: ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY. 2009;118(7):506-511

Diagnosis and Prognosis of Iatrogenic Injury of the Recurrent Laryngeal Nerve

Hydman J; Bjorck G; Persson JKE; Zedenius J; Mattsson P

Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2009;35(2):369-374

Diagnostic and prognostic potential of MIB-1 proliferation index in thyroid fine needle aspiration biopsy

Sofiadis A; Tani E; Foukakis T; Kjellman P; Skoog L; Hoog A; Wallin G; Zedenius J; Larsson C

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2009;160(2):295-299

Postoperative mortality in parathyroid surgery in Sweden during five decades: improved outcome despite older patients

Norenstedt S; Ekbom A; Brandt L; Zedenius J; Nilsson I-L

Article: WORLD JOURNAL OF SURGERY. 2008;32(7):1247-1252

Fine-needle aspiration biopsy of benign thyroid nodules: An evidence-based review

Lundgren CI; Zedenius J; Skoog L

Article: ENDOCRINE-RELATED CANCER. 2007;14(2):381-391

A PCR-based expression signature of malignancy in follicular thyroid tumors

Foukakis T; Gusnanto A; Au AYM; Hoog A; Lui W-O; Larsson C; Wallin G; Zedenius J

Article: BRITISH JOURNAL OF SURGERY. 2007;94(5):571-577

Influence of surgical and postoperative treatment on survival in differentiated thyroid cancer

Lundgren CI; Hall P; Dickman PW; Zedenius J

Article: ENDOCRINE-RELATED CANCER. 2007;14(1):135-140

The association between primary hyperparathyroidism and malignancy: nationwide cohort analysis on cancer incidence after parathyroidectomy

Nilsson I-L; Zedenius J; Yin L; Ekbom A

Article: SCANDINAVIAN JOURNAL OF SURGERY. 2007;96(1):26-30

Operation for primary hyperparathyroidism:: The new versus the old order -: A randomised controlled trial of preoperative localisation

Aarum S; Nordenstroem J; Reihner E; Zedenius J; Jacobsson H; Danielsson R; Baeckdahl M; Lindholm H; Wallin G; Hamberger B; Farnebo L-O

Article: THYROID. 2006;16(7):659-666

Are possible risk factors for differentiated thyroid cancer of prognostic importance?

Lundgren CI; Dickman PW; Zedenius J; Hall P

Article: EJSO. 2006;32(3):345-352

Predictors of outcome in patients with papillary thyroid carcinoma

Kjellman P; Zedenius J; Lundell G; Bäckdahl M; Farnebo LO; Hamberger B; Larsson C; Wallin G

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(3):1143-1149

The Ras effector NORE1A is suppressed in follicular thyroid carcinomas with a PAX8-PPARγ fusion

Foukakis T; Au AYM; Wallin G; Geli J; Forsberg L; Clifton-Bligh R; Robinson BG; Lui WO; Zedenius J; Larsson C

Article: CANCER. 2006;106(3):524-531

Clinically significant prognostic factors for differentiated thyroid carcinoma - A population-based, nested case-control study

Lundgren CI; Hall P; Dickman PW; Zedenius J

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2006;91(1):262-269

High frequency of loss of heterozygosity in imprinted, compared with nonimprinted, genomic regions in follicular thyroid carcinomas and atypical adenomas

Sarquis MS; Weber F; Shen L; Broelsch CE; Jhiang SM; Zedenius J; Frilling A; Eng C

Article: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES. 2005;113(9):516-521

Lack of mutations in the TSHr and Gsα genes in TSHr antibody negative Graves' disease

Elgadi A; Frisk T; Larsson C; Wallin G; Höög A; Zedenius J; Norgren S

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2005;152(3):459-470

Distinction in gene expression profiles demonstrated in parathyroid adenomas by high-density oligoarray technology

Forsberg L; Björck E; Hashemi J; Zedenius J; Höög A; Farnebo LO; Reimers M; Larsson C

Article: ONCOGENE. 2005;24(8):1467-1476

Expression profiling reveals a distinct transcription signature in follicular thyroid carcinomas with a PAX8-PPARγ fusion oncogene

Lui WO; Foukakis T; Lidén J; Thoppe SR; Dwight T; Höög A; Zedenius J; Wallin G; Reimers M; Larsson C

Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2005;26(1):141-149

Molecular cytogenetic characterization of primary cultures and established cell lines from non-medullary thyroid tumors

Foukakis T; Thoppe SR; Lagercrantz S; Dwight T; Weng WH; Svensson A; Höög A; Zedenius J; Wallin G; Lui WO; Larsson C

Article: INTERNATIONAL JOURNAL OF CANCER. 2003;106(4):569-573

Incidence and survival of Swedish patients with differentiated thyroid cancer

Lundgren CI; Hall P; Ekbom A; Frisell J; Zedenius J; Dickman PW

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2003;88(9):4440-4445

Involvement of the PAX8/peroxisome proliferator-activated receptor γ rearrangement in follicular thyroid tumors

Dwight T; Thoppe SR; Foukakis T; Lui WO; Wallin G; Höög A; Frisk T; Larsson C; Zedenius J

Article: THYROID. 2003;13(4):371-380

MIB-1 index in thyroid tumors:: A predictor of the clinical course in papillary thyroid carcinoma?

Kjellman P; Wallin G; Höög A; Auer G; Larsson C; Zedenius J

Article: AMERICAN JOURNAL OF PATHOLOGY. 2002;161(4):1299-1306

Independent genetic events associated with the development of multiple parathyroid tumors in patients with primary hyperparathyroidism

Dwight T; Nelson AE; Theodosopoulos G; Richardson AL; Learoyd DL; Philips J; Delbridge L; Zedenius J; Teh BT; Larsson C; Marsh DJ; Robinson BG

Article: GENES CHROMOSOMES & CANCER. 2002;35(1):74-80

Silencing of the PTEN tumor-suppressor gene in anaplastic thyroid cancer

Frisk T; Foukakis T; Dwight T; Lundberg J; Höög A; Wallin G; Eng C; Zedenius J; Larsson C

Journal article: CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY. 2002;9(1):43-50

Follicular thyroid tumors: clinical and genetic aspects

Frisk T; Larsson C; Wallin G; Zedenius J

Article: GENES CHROMOSOMES & CANCER. 2001;32(1):43-49

Gain of 1q and loss of 9q21.3-q32 are associated with a less favorable prognosis in papillary thyroid carcinoma

Kjellman P; Lagercrantz S; Höög A; Wallin G; Larsson C; Zedenius J

Article: LAKARTIDNINGEN. 2001;98(25):3024-3028

[Hereditary thyroid cancer can be cured by prophylactic surgery].

Wallin G; Bondesson AG; Farnebo LO; Hallengren B; Hamberger B; Jansson S; Nilsson O; Nordenskjöld M; Smeds S; Svensson KA; Wihlborg O; Zedenius J

Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 2001;18(6):1219-1225

CGH alterations in medullary thyroid carcinomas in relation to the RET M918T mutation and clinical outcome

Frisk T; Zedenius J; Lundberg J; Wallin G; Kytölä S; Larsson C

Article: THYROID. 2001;11(2):187-192

Surgical treatment of hyperthyroidism:: A ten-year experience

Werga-Kjellman P; Zedenius J; Tallstedt L; Träisk F; Lundel G; Wallin G

Journal article: BRITISH JOURNAL OF SURGERY. 2000;87(9):1258-1259

Expression of the RET proto-oncogene and the RET/PTC oncogenes in papillary thyroid carcinomas and its correlation to clinical manifestations

Kjellman PC; Learoyd DL; Larsson C; Wallin G; Messina M; Robinson BG; Zedenius J

Article: CLINICAL ENDOCRINOLOGY. 2000;53(1):85-92

Loss of heterozygosity in sporadic parathyroid tumours:: involvement of chromosome 1 and the MEN1 gene locus in 11q13.

Dwight T; Twigg S; Delbridge L; Wong FK; Farnebo F; Richardson AL; Nelson A; Zedenius J; Philips J; Larsson C; Teh BT; Robinson B

Article: EUROPEAN JOURNAL OF ENDOCRINOLOGY. 2000;142(6):643-649

Expression of RET and its ligand complexes, GDNF/GFRalpha-1 and NTN/GFRalpha-2, in medullary thyroid carcinomas

Frisk T; Farnebo F; Zedenius J; Grimelius L; Höög A; Wallin G; Larsson C

Article: GENES CHROMOSOMES & CANCER. 1999;26(4):322-328

Fine-structure deletion mapping of 10q22-24 identifies regions of loss of heterozygosity and suggests that sporadic follicular thyroid adenomas and follicular thyroid carcinomas develop along distinct neoplastic pathways

Yeh JJ; Marsh DJ; Zedenius J; Dwight T; Delbridge L; Robinson BG; Eng C

Article: GENES CHROMOSOMES & CANCER. 1999;26(1):35-39

Sporadic follicular thyroid tumors show loss of a 200-kb region in 11q13 without evidence for mutations in the MEN1 gene

Nord B; Larsson C; Wong FK; Wallin G; Teh BT; Zedenius J

Article: GENES CHROMOSOMES & CANCER. 1999;25(4):349-353

Low frequency of numerical chromosomal aberrations in follicular thyroid tumors detected by comparative genomic hybridization

Frisk T; Kytölä S; Wallin G; Zedenius J; Larsson C

Article: ANZ JOURNAL OF SURGERY. 1999;69(1):34-36

Multinodular goitre presenting as a clinical single nodule:: How effective is hemithyroidectomy?

Wadström C; Zedenius J; Guinea A; Reeve T; Delbridge L

Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 1998;83(10):3631-3635

RET/PTC and RET tyrosine kinase expression in adult papillary thyroid carcinomas

Learoyd DL; Messina M; Zedenius J; Guinea AI; Delbridge LW; Robinson BG

Article: ANNALS OF SURGERY. 1998;228(1):99-105

Thymic carcinoids in multiple endocrine neoplasia type 1

Teh BT; Zedenius J; Kytölä S; Skogseid B; Trotter J; Choplin H; Twigg S; Farnebo F; Giraud S; Cameron D; Robinson B; Calender A; Larsson C; Salmela P

Article: CANCER EPIDEMIOLOGY. 1998;22(6):544-548

A rapid method for DNA extraction from fine-needle aspiration biopsies of thyroid tumors, and subsequent RET mutation analysis

Zedenius J; Dwight T; Robinson BG; Delbridge L; Backdahl M; Wallin G; Larsson C; Weber G

Article: CANCER RESEARCH. 1997;57(21):4710-4713

Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors

Dahia PLM; Marsh DJ; Zheng ZM; Zedenius J; Komminoth P; Frisk T; Wallin G; Parsons R; Longy M; Larsson C; Eng C

Article: CANCER RESEARCH. 1997;57(3):500-503

Differential loss of heterozygosity in the region of the Cowden locus within 10q22-23 in follicular thyroid adenomas and carcinomas

Marsh DJ; Zheng ZM; Zedenius J; Kremer H; Padberg GW; Larsson C; Longy M; Eng C

Article: JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. 1996;276(19):1575-1579

The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2 - International RET mutation consortium analysis

Eng C; Clayton D; Schuffenecker I; Lenoir G; Cote G; Gagel RF; vanAmstel HKP; Lips CJM; Nishisho I; Takai SI; Marsh DJ; Robinson BG; FrankRaue K; Raue F; Xue FY; Noll WW; Romei C; Pacini F; Fink M; Niederle B; Zedenius J; Nordenskjold M; Komminoth P; Hendy GN; Gharib H; Thibodeau SN; Lacroix A; Frilling A; Ponder BAJ; Mulligan LM

Article: HUMAN GENETICS. 1996;97(3):299-303

Deletions of the long arm of chromosome 10 in progression of follicular thyroid tumors

Zedenius J; Wallin G; Svensson A; Bovee J; Hoog A; Backdahl M; Larsson C

Article: THYROID. 1996;6(1):1-9

Alterations of p53 and expression of WAF1/p21 in human thyroid tumors

Zedenius J; Larsson C; Wallin G; Backdahl M; Aspenblad U; Hoog A; Borresen AL; Auer G

Article: WORLD JOURNAL OF SURGERY. 1996;20(1):101-106

Stromal fibroblasts adjacent to invasive thyroid tumors: Expression of gelatinase a but not stromelysin 3 mRNA

Zedenius J; StahleBackdahl M; Enberg U; Grimelius L; Larsson C; Wallin G; Backdahl M

Article: HUMAN GENETICS. 1995;96(1):27-32

ALLELOTYPING OF FOLLICULAR THYROID-TUMORS

ZEDENIUS J; WALLIN G; SVENSSON A; GRIMELIUS L; HOOG A; LUNDELL G; BACKDAHL M; LARSSON C

Journal article: HUMAN MOLECULAR GENETICS. 1994;3(10):1775-1781

THE PHOSPHOLIPASE-C BETA-3 GENE LOCATED IN THE MEN1 REGION SHOWS LOSS OF EXPRESSION IN ENDOCRINE TUMORS

WEBER G; FRIEDMAN E; GRIMMOND S; HAYWARD NK; PHELAN C; SKOGSEID B; GOBL A; ZEDENIUS J; SANDELIN K; TEH BT; CARSON E; WHITE I; OBERG K; SHEPHERD J; NORDENSKOLD M; LARSSON C

Journal article: HUMAN MOLECULAR GENETICS. 1994;3(8):1259-1262

SOMATIC AND MEN 2A DE-NOVO MUTATIONS IDENTIFIED IN THE RET PROTOONCOGENE BY SCREENING OF SPORADIC MTC-S

ZEDENIUS J; WALLIN G; HAMBERGER B; NORDENSKJOLD M; WEBER G; LARSSON C

Journal article: SURGERY. 1992;112(6):1154-1159

ADDITION OF NUCLEAR-DNA CONTENT TO THE AMES RISK-GROUP CLASSIFICATION FOR PAPILLARY THYROID-CANCER

PASIEKA JL; ZEDENIUS J; AUER G; GRIMELIUS L; HOOG A; LUNDELL G; WALLIN G; BACKDAHL M; IRVIN G; ROSEN I; PROYE C; MCLEOD M; GRANT C; HAY I

Journal article: WORLD JOURNAL OF SURGERY. 1992;16(4):589-594

FOLLICULAR TUMORS OF THE THYROID-GLAND - DIAGNOSIS, CLINICAL ASPECTS AND NUCLEAR-DNA ANALYSIS

ZEDENIUS J; AUER G; BACKDAHL M; FALKMER U; GRIMELIUS L; LUNDELL G; WALLIN G

Article: INTERNATIONAL JOURNAL OF ONCOLOGY. 1992;33(4):861-869

Gene-specific promoter hypermethylation without global hypomethylation in follicular thyroid cancer

Lee J-J; Geli J; Larsson C; Wallin G; Karimi M; Zedenius J; Hoog A; Foukakis T

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