Volkan Özenci

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Adjungerad professor i klinisk bakteriologi vid institutionen för
laboratoriemedicin från 1 januari 2022
Primär anställning: Överläkare vid Karolinska Universitetssjukhuset

Forskningsbeskrivning

Volkan Özenci arbetar kliniskt vid Karolinska Universitetslaboratoriet och
forskar för att förbättra klinisk mikrobiologisk diagnostik. Målet är
dels att patienterna snabbare ska få effektiv behandling, dels att motverka
ökad antibiotikaresistens. Han har utvecklat en teknik för analys av
bakterier vid blodförgiftning, sepsis, som sänker tidsåtgången från 24
till 2–4 timmar. Den är idag införd på 40 procent av de stora kliniska
laboratorierna i Europa.
Hans forskargrupp genomför kliniska studier av nya produkter från en lång
rad medicintekniska bolag och har även två egna pågående ansökningar om
patent. Gruppen har också börjat forska om utveckling mot mer
miljövänliga kliniska laboratorier, mot bakgrund av att verksamheten har
extremt stor plastkonsumtion.

Undervisning

Volkan Özenci är mycket engagerad i KI:s utbildningar, och leder flera
kurser inom klinisk mikrobiologi på läkarprogrammet.

Artiklar

Journal article: MICROBIOLOGY SPECTRUM. 2024;12(1):e0361323-e03623

Performance of an innovative culture-based digital dipstick for detection of bacteriuria.

Iseri E; Nilsson S; van Belkum A; van der Wijngaart W; Özenci V
Journal article: JOURNAL OF INFECTION. 2023;87(5):428-437

European candidaemia is characterised by notable differential epidemiology and susceptibility pattern: Results from the ECMM Candida III study.

Arendrup MC; Arikan-Akdagli S; Jørgensen KM; Barac A; Steinmann J; Toscano C; Arsenijevic VA; Sartor A; Lass-Flörl C; Hamprecht A; Matos T; Rogers BRS; Quiles I; Buil J; Özenci V; Krause R; Bassetti M; Loughlin L; Denis B; Grancini A; White PL; Lagrou K; Willinger B; Rautemaa-Richardson R; Hamal P; Ener B; Unalan-Altintop T; Evren E; Hilmioglu-Polat S; Oz Y; Ozyurt OK; Aydin F; Růžička F; Meijer EFJ; Gangneux JP; Lockhart DEA; Khanna N; Logan C; Scharmann U; Desoubeaux G; Roilides E; Talento AF; van Dijk K; Koehler P; Salmanton-García J; Cornely OA; Hoenigl M
Article: ORAL ONCOLOGY. 2023;146:106556

Mycobiota profile of oral fungal infections in head and neck cancer patients receiving radiotherapy: A 6-year retrospective MALDI-TOF mass spectrometry study.

Al-Manei K; Sobkowiak MJ; Nagadia RH; Heymann R; Sällberg Chen M; Özenci V
Journal article: LANCET INFECTIOUS DISEASES. 2023;23(6):751-761

Guideline adherence and survival of patients with candidaemia in Europe: results from the ECMM Candida III multinational European observational cohort study.

Hoenigl M; Salmanton-García J; Egger M; Gangneux J-P; Bicanic T; Arikan-Akdagli S; Alastruey-Izquierdo A; Klimko N; Barac A; Özenci V; Meijer EFJ; Khanna N; Bassetti M; Rautemaa-Richardson R; Lagrou K; Adam K-M; Akalin EH; Akova M; Arsic Arsenijevic V; Aujayeb A; Blennow O; Bretagne S; Danion F; Denis B; de Jonge NA; Desoubeaux G; Drgona L; Erben N; Gori A; García Rodríguez J; Garcia-Vidal C; Giacobbe DR; Goodman AL; Hamal P; Hammarström H; Toscano C; Lanternier F; Lass-Flörl C; Lockhart DEA; Longval T; Loughlin L; Matos T; Mikulska M; Narayanan M; Martín-Pérez S; Prattes J; Rogers B; Rahimli L; Ruiz M; Roilides E; Samarkos M; Scharmann U; Sili U; Sipahi OR; Sivakova A; Steinmann J; Trauth J; Turhan O; Van Praet J; Vena A; White PL; Willinger B; Tortorano AM; Arendrup MC; Koehler P; Cornely OA; ECMM Candida III Study Group
Article: MICROBIOLOGY SPECTRUM. 2023;11(2):e0500122-e05022

Analytical Performance and Potential Clinical Utility of EUCAST Rapid Antimicrobial Susceptibility Testing in Blood Cultures after Four Hours of Incubation.

Ekwall-Larson A; Fröding I; Mert B; Åkerlund A; Özenci V
Journal article: LANCET MICROBE. 2023;4(1):e47-e56

The current state of laboratory mycology and access to antifungal treatment in Europe: a European Confederation of Medical Mycology survey.

Salmanton-García J; Hoenigl M; Gangneux J-P; Segal E; Alastruey-Izquierdo A; Arikan Akdagli S; Lagrou K; Özenci V; Vena A; Cornely OA
Article: JOURNAL OF EDUCATIONAL EVALUATION FOR HEALTH PROFESSIONS. 2023;20:32

ChatGPT (GPT-3.5) as an assistant tool in microbial pathogenesis studies in Sweden: a cross-sectional comparative study.

Hultgren C; Lindkvist A; Özenci V; Curbo S
Article: MICROBIOLOGY SPECTRUM. 2022;10(6):e0248722-e02422

Clinical Microbial Identification of Severe Oral Infections by MALDI-TOF Mass Spectrometry in Stockholm County: an 11-Year (2010 to 2020) Epidemiological Investigation.

Al-Manei K; Ghorbani M; Naud S; Al-Manei KK; Sobkowiak MJ; Lund B; Hazirolan G; Sällberg Chen M; Özenci V
Article: LAKARTIDNINGEN. 2022;119:22050

[Four blood culture bottles from one venipuncture instead of divided into two: new Swedish national recommendation for blood culture].

Özenci V; Sundqvist M; Strålin K
Article: JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY. 2022;234:112547

Photo-oxidative stress response and virulence traits are co-regulated in E. faecalis after antimicrobial photodynamic therapy.

Manoil D; Parga A; Hellesen C; Khawaji A; Brundin M; Durual S; Özenci V; Fang H; Belibasakis GN
Article: JOURNAL OF FUNGI. 2022;8(8):832

Combining T2Bacteria and T2Candida Panels for Diagnosing Intra-Abdominal Infections: A Prospective Multicenter Study.

Krifors A; Ullberg M; Castegren M; Petersson J; Sparrelid E; Özenci V; Blennow O
Journal article: EGE TIP DERGISI. 2022;61(2):133-138

Kan kültüründe bakterilerin hızlı tanısı ve duyarlılıklarının saptanması

KAYIN DİNÇ M; ÖZENCİ V; AYDEMİR SŞ
Article: CRITICAL CARE MEDICINE. 2022;50(5):825-836

Ventilator-Associated Lower Respiratory Tract Bacterial Infections in COVID-19 Compared With Non-COVID-19 Patients.

Hedberg P; Ternhag A; Giske CG; Strålin K; Özenci V; Johansson N; Spindler C; Hedlund J; Mårtensson J; Nauclér P
Article: MICROBIOLOGY SPECTRUM. 2022;10(2):e0210721-e02121

Performance of dRAST on Prospective Clinical Blood Culture Samples in a Simulated Clinical Setting and on Multidrug-Resistant Bacteria.

Wong AYW; Johnsson ATA; Özenci V
Article: INTENSIVE CARE MEDICINE EXPERIMENTAL. 2022;10(1):14

Evaluation of an extracorporeal ozone-based bactericide system for the treatment of Escherichia coli sepsis.

Skorup P; Fransson A; Gustavsson J; Sjöholm J; Rundgren H; Özenci V; Wong AYW; Karlsson T; Svensén C; Günther M
Article: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS. 2022;21(1):7

Correlation of clinical sepsis definitions with microbiological characteristics in patients admitted through a sepsis alert system; a prospective cohort study.

Yu D; Unger D; Unge C; Parke Å; Sundén-Cullberg J; Strålin K; Özenci V
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2022;60(2):e0193521-e01921

Single-Site Sampling versus Multisite Sampling for Blood Cultures: a Retrospective Clinical Study.

Ekwall-Larson A; Yu D; Dinnétz P; Nordqvist H; Özenci V
Article: JOURNAL OF FUNGI. 2022;8(1):86

T2Candida Assay in the Diagnosis of Intraabdominal Candidiasis: A Prospective Multicenter Study.

Krifors A; Ullberg M; Castegren M; Petersson J; Sparrelid E; Hammarström H; Sjölin J; Özenci V; Blennow O
Article: ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS. 2021;20(1):51

Secondary bacterial infections and antimicrobial resistance in COVID-19: comparative evaluation of pre-pandemic and pandemic-era, a retrospective single center study.

Karataş M; Yaşar-Duman M; Tünger A; Çilli F; Aydemir Ş; Özenci V
Article: SCIENCE TRANSLATIONAL MEDICINE. 2021;13(599):eabb3107

A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells.

Zimmer CL; von Seth E; Buggert M; Strauss O; Hertwig L; Nguyen S; Wong AYW; Zotter C; Berglin L; Michaëlsson J; Hansson MR; Arnelo U; Sparrelid E; Ellis ECS; Söderholm JD; Keita ÅV; Holm K; Özenci V; Hov JR; Mold JE; Cornillet M; Ponzetta A; Bergquist A; Björkström NK
Article: MICROORGANISMS. 2021;9(4):827

Comparison of Four Streptococcus pneumoniae Urinary Antigen Tests Using Automated Readers.

Wong AYW; Johnsson ATA; Ininbergs K; Athlin S; Özenci V
Article: APMIS. 2021;129(4):178-185

Identification of microorganisms directly from blood culture bottles with polymicrobial growth: comparison of FilmArray and direct MALDI-TOF MS.

Almuhayawi MS; Wong AYW; Kynning M; Lüthje P; Ullberg M; Özenci V
Article: MUCOSAL IMMUNOLOGY. 2021;14(2):357-365

Human endometrial MAIT cells are transiently tissue resident and respond to Neisseria gonorrhoeae.

Bister J; Crona Guterstam Y; Strunz B; Dumitrescu B; Haij Bhattarai K; Özenci V; Brännström M; Ivarsson MA; Gidlöf S; Björkström NK
Article: MICROORGANISMS. 2021;9(3):493

Evaluation of Four Lateral Flow Assays for the Detection of Legionella Urinary Antigen.

Wong AYW; Johnsson ATA; Iversen A; Athlin S; Özenci V
Article: GUT MICROBES. 2021;13(1):1983101

Isolation of pancreatic microbiota from cystic precursors of pancreatic cancer with intracellular growth and DNA damaging properties.

Halimi A; Gabarrini G; Sobkowiak MJ; Ateeb Z; Davanian H; Gaiser RA; Arnelo U; Valente R; Wong AYW; Moro CF; Del Chiaro M; Özenci V; Chen MS
Article: JOURNAL OF MICROBIOLOGICAL METHODS. 2020;177:106027

The impact of delayed analysis of positive blood cultures on the performance of short-term culture followed by MALDI-TOF MS.

Johnsson ATA; Wong AYW; Özenci V
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2020;58(9):e01860-e01819

Performance of PCR/Electrospray Ionization-Mass Spectrometry on Whole Blood for Detection of Bloodstream Microorganisms in Patients with Suspected Sepsis.

Strålin K; Rothman RE; Özenci V; Barkataki K; Brealey D; Dhiman N; Poling L; Kurz MC; Limaye AP; LoVecchio F; Lowery K; Miller LG; Moran GJ; Overcash JS; Parekh A; Peacock WF; Rivers EP; Sims M; Stubbs AM; Sundqvist M; Ullberg M; Carroll KC
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2020;39(1):139-149

Identification and antimicrobial susceptibility testing of Gram-positive and Gram-negative bacteria from positive blood cultures using the Accelerate Pheno™ system.

Ullberg M; Özenci V
Article: PLOS ONE. 2020;15(11):e0242533

Low prevalence of bloodstream infection and high blood culture contamination rates in patients with COVID-19.

Yu D; Ininbergs K; Hedman K; Giske CG; Strålin K; Özenci V
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:2003

Circulating and Salivary Antibodies to Fusobacterium nucleatum Are Associated With Cystic Pancreatic Neoplasm Malignancy.

Alkharaan H; Lu L; Gabarrini G; Halimi A; Ateeb Z; Sobkowiak MJ; Davanian H; Fernández Moro C; Jansson L; Del Chiaro M; Özenci V; Sällberg Chen M
Article: FRONTIERS IN MICROBIOLOGY. 2020;11:1639

Single-Sampling Strategy vs. Multi-Sampling Strategy for Blood Cultures in Sepsis: A Prospective Non-inferiority Study.

Yu D; Larsson A; Parke Å; Unge C; Henning C; Sundén-Cullberg J; Somell A; Strålin K; Özenci V
Article: MYCOSES. 2019;62(11):1043-1048

Estimated burden of fungal infections in Sweden.

Özenci V; Klingspor L; Ullberg M; Chryssanthou E; Denning DW; Kondori N
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2019;38(11):2133-2143

Comparison of rapid BACpro® II, Sepsityper® kit and in-house preparation methods for direct identification of bacteria from blood cultures by MALDI-TOF MS with and without Sepsityper® module analysis.

Kayin M; Mert B; Aydemir S; Özenci V
Article: MYCOSES. 2019;62(10):920-927

ECMM CandiReg-A ready to use platform for outbreaks and epidemiological studies.

Koehler P; Arendrup MC; Arikan-Akdagli S; Bassetti M; Bretagne S; Klingspor L; Lagrou K; Meis JF; Rautemaa-Richardson R; Schelenz S; Hamprecht A; Koehler FC; Kurzai O; Salmanton-García J; Vehreschild J-J; Alanio A; Alastruey-Izquierdo A; Arsic Arsenijevic V; Gangneux J-P; Gow NAR; Hadina S; Hamal P; Johnson E; Klimko N; Lass-Flörl C; Mares M; Özenci V; Papp T; Roilides E; Sabino R; Segal E; Talento AF; Tortorano AM; Verweij PE; Hoenigl M; Cornely OA; European Confederation of Medical Mycology (ECMM)
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2019;57(8):e01535-e01518

Evaluation of the Sofia S. pneumoniae FIA for Detection of Pneumococcal Antigen in Patients with Bloodstream Infection.

Olofsson E; Özenci V; Athlin S
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2019;57(8):e00268-e00219

Detailed Analysis of the Characteristics of Sample Volume in Blood Culture Bottles.

Henning C; Aygül N; Dinnétz P; Wallgren K; Özenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2019;38(6):1071-1077

Coexistence of Candida species and bacteria in patients with cystic fibrosis.

Haiko J; Saeedi B; Bagger G; Karpati F; Özenci V
Article: ANAEROBE. 2019;57:59-62

Short-term culture for rapid identification of anaerobic bacteria from blood cultures.

Rassolie A; Özenci V
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2019;74(Suppl 1):i2-i5

Rapid microbial identification and antimicrobial susceptibility testing to drive better patient care: an evolving scenario.

Özenci V; Rossolini GM
Article: PLOS ONE. 2019;14(2):e0212812

PCR with electrospray ionization-mass spectrometry on bronchoalveolar lavage for detection of invasive mold infections in hematological patients.

Krifors A; Özenci V; Ullberg M; Ackefors M; Jädersten M; Strålin K; Blennow O
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2018;37(12):2261-2272

Infective endocarditis due to Streptococcus dysgalactiae: clinical presentation and microbiological features.

Bläckberg A; Nilson B; Özenci V; Olaison L; Rasmussen M
Article: MYCOSES. 2018;61(10):777-785

Epidemiology of fungaemia in Sweden: A nationwide retrospective observational survey.

Klingspor L; Ullberg M; Rydberg J; Kondori N; Serrander L; Swanberg J; Nilsson K; Jendle Bengtén C; Johansson M; Granlund M; Törnqvist E; Nyberg A; Kindlund K; Ygge M; Kartout-Boukdir D; Toepfer M; Hålldin E; Kahlmeter G; Özenci V
Article: LAKARTIDNINGEN. 2018;115:EWWI

Ny molekylärbiologisk metod skrotades trots god potential - Förlust av värdefullt verktyg inom infektionsdiagnostiken visar att icke-vinstdrivande testutveckling kanske behövs.

Strålin K; Ullberg M; Özenci V
Article: MYCOSES. 2018;61(3):179-185

Seven years of clinical experience with the Yeast Traffic Light PNA FISH: Assay performance and possible implications on antifungal therapy.

Klingspor L; Lindbäck E; Ullberg M; Özenci V
Article: CLINICAL INFECTIOUS DISEASES. 2018;66(3):452-455

Demise of Polymerase Chain Reaction/Electrospray Ionization-Mass Spectrometry as an Infectious Diseases Diagnostic Tool.

Özenci V; Patel R; Ullberg M; Strålin K
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2017;36(10):1933-1938

Comparison of the ImmuView and the BinaxNOW antigen tests in detection of Streptococcus pneumoniae and Legionella pneumophila in urine.

Athlin S; Iversen A; Özenci V
Article: JOURNAL OF MICROBIOLOGICAL METHODS. 2017;136:17-20

Identification of microorganisms grown on chromogenic media by MALDI-TOF MS.

Lüthje P; Pranada AB; Carruthers-Lay D; Desjardins M; Gaillot O; Wareham D; Ciesielczuk H; Özenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2017;36(4):657-662

Genomic analysis reveals the presence of a class D beta-lactamase with broad substrate specificity in animal bite associated Capnocytophaga species.

Zangenah S; Andersson AF; Özenci V; Bergman P
Article: PLOS ONE. 2017;12(1):e0170033

Broad-Range Detection of Microorganisms Directly from Bronchoalveolar Lavage Specimens by PCR/Electrospray Ionization-Mass Spectrometry.

Ullberg M; Lüthje P; Mölling P; Strålin K; Özenci V
Article: CLINICAL INFECTIOUS DISEASES. 2016;63(10):1332-1339

Individualized Approaches Are Needed for Optimized Blood Cultures.

Banerjee R; Özenci V; Patel R
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2016;54(4):1148-1151

Controlled Evaluation of the New BacT/Alert Virtuo Blood Culture System for Detection and Time to Detection of Bacteria and Yeasts.

Altun O; Almuhayawi M; Lüthje P; Taha R; Ullberg M; Özenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2016;35(4):579-585

Rapid identification of Streptococcus pneumoniae in blood cultures by using the ImmuLex, Slidex and Wellcogen latex agglutination tests and the BinaxNOW antigen test.

Altun O; Athlin S; Almuhayawi M; Strålin K; Özenci V
Article: INTERNATIONAL ENDODONTIC JOURNAL. 2016;49(4):343-351

The origin of endodontic Enterococcus faecalis explored by comparison of virulence factor patterns and antibiotic resistance to that of isolates from stool samples, blood cultures and food.

Vidana R; Rashid MU; Özenci V; Weintraub A; Lund B
Article: ANAEROBE. 2016;38:21-24

Microbiological diagnosis of Eggerthella lenta blood culture isolates in a Swedish tertiary hospital: Rapid identification and antimicrobial susceptibility profile.

Liderot K; Ratcliffe P; Lüthje P; Thidholm E; Özenci V
Article: PLOS ONE. 2016;11(7):e0159694

The IRIDICA PCR/Electrospray Ionization-Mass Spectrometry Assay on Bronchoalveolar Lavage for Bacterial Etiology in Mechanically Ventilated Patients with Suspected Pneumonia.

Strålin K; Ehn F; Giske CG; Ullberg M; Hedlund J; Petersson J; Spindler C; Özenci V
Article: JOURNAL OF MEDICAL MICROBIOLOGY. 2015;64(11):1346-1352

Rapid identification of bacteria from positive blood culture bottles by MALDI-TOF MS following short-term incubation on solid media.

Altun O; Botero-Kleiven S; Carlsson S; Ullberg M; Özenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2015;34(8):1583-1588

The Uni-Gold™ Streptococcus pneumoniae urinary antigen test: an interassay comparison with the BinaxNOW® Streptococcus pneumoniae test on consecutive urine samples and evaluation on patients with bacteremia.

Athlin S; Altun O; Eriksen HB; Özenci V; Strålin K
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2015;53(2):710-712

Rapid identification of microorganisms from sterile body fluids by use of FilmArray.

Altun O; Almuhayawi M; Ullberg M; Özenci V
Article: PLOS ONE. 2015;10(11):e0142398

The Performance of the Four Anaerobic Blood Culture Bottles BacT/ALERT-FN, -FN Plus, BACTEC-Plus and -Lytic in Detection of Anaerobic Bacteria and Identification by Direct MALDI-TOF MS.

Almuhayawi M; Altun O; Abdulmajeed AD; Ullberg M; Özenci V
Article: CRITICAL CARE. 2014;18(5):488

Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep.

Fenhammar J; Rundgren M; Hultenby K; Forestier J; Taavo M; Kenne E; Weitzberg E; Eriksson S; Ozenci V; Wernerson A; Frithiof R
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2014;52(9):3230-3236

Identification of microorganisms by FilmArray and matrix-assisted laser desorption ionization-time of flight mass spectrometry prior to positivity in the blood culture system.

Almuhayawi M; Altun O; Strålin K; Ozenci V
Article: PLOS ONE. 2014;9(8):e103274

A multicentre hospital outbreak in Sweden caused by introduction of a vanB2 transposon into a stably maintained pRUM-plasmid in an Enterococcus faecium ST192 clone.

Sivertsen A; Billström H; Melefors Ö; Liljequist BO; Wisell KT; Ullberg M; Özenci V; Sundsfjord A; Hegstad K
Journal article: CRITICAL CARE. 2014;18(5):488

Renal effects of treatment with a TLR4-inhibitor in conscious septic sheep

Fenhammar J; Rundgren M; Hultenby K; Forestier J; Taavo M; Kenne E; Weitzberg E; Eriksson S; Ozenci V; Wernerson A; Frithiof R
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2013;51(12):4130-4136

Clinical evaluation of the FilmArray blood culture identification panel in identification of bacteria and yeasts from positive blood culture bottles.

Altun O; Almuhayawi M; Ullberg M; Ozenci V
Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2013;77(3):216-219

Comparison of MALDI-TOF MS and VITEK 2 system for laboratory diagnosis of Granulicatella and Abiotrophia species causing invasive infections.

Ratcliffe P; Fang H; Thidholm E; Boräng S; Westling K; Özenci V
Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2013;77(2):96-98

Identification of clinical Pasteurella isolates by MALDI-TOF -- a comparison with VITEK 2 and conventional microbiological methods.

Zangenah S; Güleryüz G; Boräng S; Ullberg M; Bergman P; Ozenci V
Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2013;77(1):1-4

The performance of 4 different supplements and 5 blood culture bottles types in detection of bacteria and Candida spp. in simulated sterile body fluid cultures.

Nylén T; Saeedi B; Borg C; Ullberg M; Özenci V
Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2013;76(3):286-290

Transport time for blood culture bottles: underlying factors and its consequences.

Rönnberg C; Mildh M; Ullberg M; Özenci V
Article: BIOMED RESEARCH INTERNATIONAL. 2013;2013:376219-6

Secondary bacterial infections in patients with seasonal influenza A and pandemic H1N1.

Liderot K; Ahl M; Ozenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2012;31(11):3073-3077

Evaluation of species-specific PCR, Bruker MS, VITEK MS and the VITEK 2 system for the identification of clinical Enterococcus isolates.

Fang H; Ohlsson A-K; Ullberg M; Ozenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2012;31(11):2983-2987

Comparison of the two blood culture systems, Bactec 9240 and BacT/Alert 3D, in the detection of Candida spp. and bacteria with polymicrobial sepsis.

Klingspor L; Muhammed SA; Ozenci V
Article: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. 2012;31(10):2631-2637

Identification of blood and wound isolates of C. canimorsus and C. cynodegmi using VITEK2 and MALDI-TOF.

Zangenah S; Ozenci V; Boräng S; Bergman P
Article: DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE. 2012;73(2):153-156

Clinical comparison of the Bactec Mycosis IC/F, BacT/Alert FA, and BacT/Alert FN blood culture vials for the detection of candidemia.

Ericson E-L; Klingspor L; Ullberg M; Ozenci V
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2012;50(2):522-524

Pneumonia and bacteremia due to Kytococcus schroeteri.

Blennow O; Westling K; Fröding I; Ozenci V
Article: JOURNAL OF CLINICAL MICROBIOLOGY. 2010;48(10):3810-3812

Polymicrobial bloodstream infection with Eggerthella lenta and Desulfovibrio desulfuricans.

Liderot K; Larsson M; Boräng S; Ozenci V
Journal article: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2009;33:s47

126 RELAPSING ENDOCARDITIS DUE TO GRANULICATELLA ADIACENS

Özenci V; Salaj D; Fang H; Westling K
Article: CLINICAL MICROBIOLOGY AND INFECTION. 2008;14(2):177-180

Rapid culture and identification: a practical method for early preliminary laboratory diagnosis of sepsis.

Ozenci V; Tegmark-Wisell K; Lundberg C; Wretlind B
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2007;56(7):973-984

A short-term dietary supplementation with high doses of vitamin E increases NK cell cytolytic activity in advanced colorectal cancer patients.

Hanson MGV; Ozenci V; Carlsten MCV; Glimelius BL; Frödin J-EA; Masucci G; Malmberg K-J; Kiessling RVR
Article: JOURNAL OF IMMUNOLOGY. 2006;177(10):7398-7405

CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients.

Miller AM; Lundberg K; Ozenci V; Banham AH; Hellström M; Egevad L; Pisa P
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2006;144(2):290-298

Modulation of immune responses and suppression of experimental autoimmune myasthenia gravis by surgical denervation of the spleen.

Bakhiet M; Yu L-Y; Ozenci V; Khan A; Shi F-D
Article: PROSTATE. 2005;65(1):20-26

Presence and specificity of tumor associated lymphocytes from ascites fluid in prostate cancer.

Ozenci V; Miller AM; Palmborg A; Egevad L; Jaremko GA; Kälkner KM; Pisa P
Article: JOURNAL OF IMMUNOTHERAPY. 2005;28(4):389-395

Immune monitoring in a phase 1 trial of a PSA DNA vaccine in patients with hormone-refractory prostate cancer.

Miller AM; Ozenci V; Kiessling R; Pisa P
Article: BRITISH JOURNAL OF CANCER. 2004;91(4):688-694

A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer.

Pavlenko M; Roos A-K; Lundqvist A; Palmborg A; Miller AM; Ozenci V; Bergman B; Egevad L; Hellström M; Kiessling R; Masucci G; Wersäll P; Nilsson S; Pisa P
Article: NEUROIMMUNOMODULATION. 2004;11(2):113-118

Splenic denervation suppresses mRNA gene expression and protein production of IL-1beta and IL-6 by peritoneal macrophages in both Trypanosoma brucei brucei-infected and non-infected rats.

Liu Y; Li Z; Svarén-Quiding C; Cui J; Ozenci V; Bakhiet M
Article: MULTIPLE SCLEROSIS JOURNAL. 2002;8(5):396-404

Cytokines in multiple sclerosis: methodological aspects and pathogenic implications.

Ozenci V; Kouwenhoven M; Link H
Article: JOURNAL OF NEUROIMMUNOLOGY. 2002;126(1-2):161-171

Monocyte-derived dendritic cells express and secrete matrix-degrading metalloproteinases and their inhibitors and are imbalanced in multiple sclerosis.

Kouwenhoven M; Ozenci V; Tjernlund A; Pashenkov M; Homman M; Press R; Link H
Article: NEUROLOGY. 2002;58(3):476-478

Non-T(H)1 cytokines are augmented systematically early in Guillain-Barré syndrome.

Press R; Ozenci V; Kouwenhoven M; Link H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;118(2):304-308

Increased levels of circulating acetylcholine receptor (AChR)-reactive IL-10-secreting cells are characteristic for myasthenia gravis (MG).

Huang YM; Kivisäkk P; Ozenci V; Pirskanen R; Link H
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2001;120(1):147-153

Multiple sclerosis is associated with an imbalance between tumour necrosis factor-alpha (TNF-alpha)- and IL-10-secreting blood cells that is corrected by interferon-beta (IFN-beta) treatment.

Ozenci V; Kouwenhoven M; Huang YM; Kivisäkk P; Link H
Article: CLINICAL AND VACCINE IMMUNOLOGY. 2001;8(6):1248-1257

Enzyme-linked immunospot assays provide a sensitive tool for detection of cytokine secretion by monocytes.

Kouwenhoven M; Ozenci V; Teleshova N; Hussein Y; Huang YM; Eusebio A; Link H
Article: CLINICAL IMMUNOLOGY. 2001;101(1):106-112

Systemic immune response in whiplash injury and ankle sprain: elevated IL-6 and IL-10.

Kivioja J; Ozenci V; Rinaldi L; Kouwenhoven M; Lindgren U; Link H
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2001;21(5):365-375

Matrix metalloproteinase and cytokine profiles in monocytes over the course of stroke.

Kouwenhoven M; Carlström C; Ozenci V; Link H
Article: JOURNAL OF CLINICAL IMMUNOLOGY. 2001;21(4):272-277

Chemokines and their receptors in whiplash injury: elevated RANTES and CCR-5.

Kivioja J; Rinaldi L; Ozenci V; Kouwenhoven M; Kostulas N; Lindgren U; Link H
Article: JOURNAL OF AUTOIMMUNITY. 2001;16(4):463-470

Multiple sclerosis: elevated expression of matrix metalloproteinases in blood monocytes.

Kouwenhoven M; Ozenci V; Gomes A; Yarilin D; Giedraitis V; Press R; Link H
Article: JOURNAL OF NEUROIMMUNOLOGY. 2001;114(1-2):242-252

IL-12/IL-12R system in multiple sclerosis.

Ozenci V; Pashenkov M; Kouwenhoven M; Rinaldi L; Söderström M; Link H
Article: JOURNAL OF NEUROIMMUNOLOGY. 2001;112(1-2):197-205

Monocytes in multiple sclerosis: phenotype and cytokine profile.

Kouwenhoven M; Teleshova N; Ozenci V; Press R; Link H
Article: EUROPEAN CYTOKINE NETWORK. 2000;11(3):456-463

Phenotypes and cytokine profiles of enriched blood dendritic cells in healthy individuals.

Pashenkov M; Kouwenhoven MC; Ozenci V; Huang YM
Article: CYTOKINE. 2000;12(8):1218-1224

IL-12 elispot assays to detect and enumerate IL-12 secreting cells.

Ozenci V; Kouwenhoven M; Press R; Link H; Huang YM
Article: JOURNAL OF NEUROIMMUNOLOGY. 2000;108(1-2):236-243

Multiple sclerosis: pro- and anti-inflammatory cytokines and metalloproteinases are affected differentially by treatment with IFN-beta.

Ozenci V; Kouwenhoven M; Teleshova N; Pashenkov M; Fredrikson S; Link H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2000;51(3):312-320

Elevated CD40 ligand expressing blood T-cell levels in multiple sclerosis are reversed by interferon-beta treatment.

Teleshova N; Bao W; Kivisäkk P; Ozenci V; Mustafa M; Link H
Article: JOURNAL OF NEUROIMMUNOLOGY. 1999;99(1):82-90

Multiple sclerosis is associated with high levels of circulating dendritic cells secreting pro-inflammatory cytokines.

Huang YM; Xiao BG; Ozenci V; Kouwenhoven M; Teleshova N; Fredrikson S; Link H
Article: JOURNAL OF AUTOIMMUNITY. 1999;12(4):297-303

Metalloproteinases and their tissue inhibitors in multiple sclerosis.

Ozenci V; Rinaldi L; Teleshova N; Matusevicius D; Kivisäkk P; Kouwenhoven M; Link H
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 1999;49(5):554-561

Multiple sclerosis: levels of interleukin-10-secreting blood mononuclear cells are low in untreated patients but augmented during interferon-beta-1b treatment.

Ozenci V; Kouwenhoven M; Huang YM; Xiao B; Kivisäkk P; Fredrikson S; Link H
Article: CLINICAL AND VACCINE IMMUNOLOGY. 1999;6(3):415-419

A new cell enzyme-linked immunosorbent assay demonstrates gamma interferon suppression by beta interferon in multiple sclerosis.

Bakhiet M; Ozenci V; Withagen C; Mustafa M; Fredrikson S; Link H
Article: MULTIPLE SCLEROSIS JOURNAL. 1999;5(2):101-104

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis.

Matusevicius D; Kivisäkk P; He B; Kostulas N; Ozenci V; Fredrikson S; Link H
Journal article: MULTIPLE SCLEROSIS JOURNAL. 1999;5(2):101-104

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

Matusevicius D; Kivisäkk P; He B; Kostulas N; Özenci V; Fredrikson S; Link H
Article: JOURNAL OF NEUROIMMUNOLOGY. 1998;91(1-2):108-112

No evidence for elevated numbers of mononuclear cells expressing MCP-1 and RANTES mRNA in blood and CSF in multiple sclerosis.

Kivisäkk P; Teleshova N; Ozenci V; Huang Y; Matusevicius D; Fredrikson S; Söderström M; Link H
Journal article:

Guideline Adherence Predicts Survival of Candidemia in Europe: Results from the ECMM Candida III Multinational European Study

Hoenigl M; Salmanton-Garcia J; Egger M; Gangneux J-P; Bicanic T; Arikan-Akdagli S; Alastruey-Izquierdo A; Klimko N; Barac A; Özenci V; Meijer EFJ; Khanna N; Bassetti M; Rautemaa-Richardson R; Lagrou K; Adam K-M; Akalın EH; Akova M; Arsic-Arsenijevic V; Aujayeb A; Blennow O; Bretagne S; Danion F; Denis B; de Jonge NA; Desoubeaux G; Drgona L; Erben N; Gori A; Rodríguez JG; Garcia-Vidal C; Giacobbe DR; Goodman AL; Hamal P; Hammarström H; Toscano C; Lanternier F; Lass-Flörl C; Lockhart DEA; Longval T; Loughlin L; Matos T; Mikulska M; Narayanan M; Martín-Pérez S; Prattes J; Rogers B; Rahimli L; Ruiz M; Roilides E; Samarkos M; Scharmann U; Sili U; Sipahi OR; Siváková A; Steinmann J; Trauth J; Turhan Ö; Van Praet J; Vena A; White L; Willinger B; Tortorano AM; Arendrup MC; Koehler P; Cornely OA; Group ECMMCII
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Preprint: 2023;bioRxiv

Alpha-toxin elicited CX3CL1-release via ADAM10 in Staphylococcus aureus pneumonia impairs bactericidal function of human monocytes

Shambat SM; Chen P; Barilla RM; Huemer M; Snäll J; Welin A; Cohen TS; Takahashi V; Berry SB; Gómez-Mejia A; Schweizer TA; Cunoosamy DM; Cajander S; Lourda M; Özenci V; Maggio EM; Schüpbach RA; Strålin K; Zinkernagel AS; Norrby-Teglund A; Svensson M
Corrigendum: JOURNAL OF CLINICAL MICROBIOLOGY. 2022;60(9):e0118022-e01122

Correction for Ekwall-Larson et al., "Single-Site Sampling versus Multisite Sampling for Blood Cultures: a Retrospective Clinical Study".

Ekwall-Larson A; Yu D; Dinnétz P; Nordqvist H; Özenci V
Preprint: 2022;bioRxiv

Evolution towards small colony variants of pandemic multidrug resistant ST131 Escherichia coli isolates from a 10-year bone infection

Li F; Lüthje P; Shafeeq S; Ahl M; Trcek J; Lacosta AD; Özenci V; Ullberg M; Åkerlund B; Römling U
Conference publication: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY. 2022;270:E94

Human endometrial mait cells are transiently tissue resident and respond to neisseria gonorrhoeae

Guterstam YC; Bister J; Strunz B; Dumitrescu B; Bhattarai KH; Ozenci V; Brannstrom M; Ivarsson M; Gidlof S; Bjorkstrom N
Preprint: 2022;SSRN Electronic Journal

Guideline Adherence Predicts Survival of Candidemia in Europe: Results from the ECMM Candida III Multinational European Study

Hoenigl M; Salmanton-Garcia J; Egger M; Gangneux J-P; Bicanic T; Arikan-Akdagli S; Alastruey-Izquierdo A; Klimko N; Barac A; Özenci V; Meijer EFJ; Khanna N; Bassetti M; Rautemaa-Richardson R; Lagrou K; Adam K-M; Akalın EH; Akova M; Arsic-Arsenijevic V; Aujayeb A; Blennow O; Bretagne S; Danion F; Denis B; de Jonge NA; Desoubeaux G; Drgona L; Erben N; Gori A; Rodríguez JG; Garcia-Vidal C; Giacobbe DR; Goodman AL; Hamal P; Hammarström H; Toscano C; Lanternier F; Lass-Flörl C; Lockhart DEA; Longval T; Loughlin L; Matos T; Mikulska M; Narayanan M; Martín-Pérez S; Prattes J; Rogers B; Rahimli L; Ruiz M; Roilides E; Samarkos M; Scharmann U; Sili U; Sipahi OR; Siváková A; Steinmann J; Trauth J; Turhan Ö; Van Praet J; Vena A; White L; Willinger B; Tortorano AM; Arendrup MC; Koehler P; Cornely OA; Group ECIS
Preprint: 2022;SSRN Electronic Journal

Management and Reduction of Clinical Microbiology Laboratory Waste: Time to Act

ÖZENCI V; Klingler J; Erdal NB; Forsberg E; Veliz SZ
Preprint: 2021;medRxiv

Evaluation of an ultra-rapid antibiotic susceptibility testing method on positive blood cultures with Escherichia coli

Baltekin Ö; Johnsson ATA; Wong AYW; Nilsson K; Mert B; Söderberg L; Wistrand-Yuen E; Özenci V
Preprint: 2021;Research Square

Correlation of Clinical Sepsis Definitions with Microbiological Characteristics in Patients Admitted Through a Sepsis Alert System; A Prospective Cohort Study

Yu D; Unger D; Unge C; Parke Å; Sundén-Cullberg J; Strålin K; Özenci V
Preprint: 2021;Research Square

Secondary Bacterial Infections and Antimicrobial Resistance in COVID-19: Comparative Evaluation of Pre-Pandemic and Pandemic-Era, A Retrospective Single Center Study

Karataş M; Duman MY; Tünger A; Çilli F; Aydemir Ş; Ozenci V
Editorial comment: JOURNAL OF GLOBAL HEALTH. 2020;10(2):020330

Lessons from COVID-19 on the role of the state and the market in providing early testing.

Morel CM; Lindahl O; Özenci V
Review: EXPERT REVIEW OF MOLECULAR DIAGNOSTICS. 2019;19(5):389-395

Clinical implementation of molecular methods in detection of microorganisms from blood with a special focus on PCR electrospray ionization mass spectrometry.

Özenci V; Strålin K
Letter: CLINICAL INFECTIOUS DISEASES. 2019;68(2):351

Reply to Spyridou et al.

Strålin K; Patel R; Ullberg M; Özenci V
Editorial comment: ACTA PAEDIATRICA. 2019;108(1):169-170

Earlier and more targeted treatment of neonatal sepsis.

Özenci V; Schubert U
Book chapter: 2018;p. 481-490

PCR/Electrospray Ionization-Mass Spectrometry as an Infectious Disease Diagnostic Tool

Özenci V; Strålin K
Conference publication: MEDICAL MYCOLOGY. 2018;56:S61

Epidemiology of fungaemia and fungal meningitis in Sweden: a nationwide retrospective observational survey from sept 2015-aug 2016

Klingspor; Ozenci V; Ullberg M; Rydberg J; Kondori N; Serrander L; Swanberg J; Nilsson K; Bengten CJ; Johansson M; Sjoberg B; Granlund M; Tornqvist E; Sjogren S; Sundqvist-Persson A-L; Kindlund K; Ygge M; Kartoutboukir D; Toepfer M; Halldin E; Nyberg A; Kahlmeter G
Letter: JOURNAL OF CLINICAL MICROBIOLOGY. 2015;53(2):750

FilmArray: correction of previously false-positive results by improved software.

Altun O; Özenci V
Conference publication: MYCOSES. 2013;56:73-74

Prospective clinical evaluation of yeast traffic light assay PNA FISH assay

Ozenci V; Klingspor L; Van den Tempel S; Ullberg M
Conference publication: MYCOSES. 2009;52:43

Clinical comparison of the two blood culture systems for the detection of candidemia

Ericson EL; Klingspor L; Ullberg M; Ozenci V
Conference publication: INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. 2009;33:S47

RELAPSING ENDOCARDITIS DUE TO GRANULICATELLA ADIACENS

Ozenci V; Salaj D; Fang H; Westling K
Conference publication: JOURNAL OF LEUKOCYTE BIOLOGY. 2000;:33

IL-12/IL-12R system in multiple sclerosis

Özenci V; Pashenkov M; Kouwenhoven M; Rinaldi L; Söderström M; Link H
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 1999;10:448A

Selective increase of CD1a expression and IFN-γ secretion by dendritic cells in multiple sclerosis

Huang YM; Özenci V; Kouwenhoven M; Huang WX; Hillert J; Xiao BG; Link H
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Forskningsbidrag

REVOM: Real-time sample volume measurement for blood cultures

VINNOVA

1 March 2023 - 30 April 2024
Early Pancreatic Cancer - Understanding the Role of Oral Microbiota

Swedish Research Council

1 January 2021 - 31 December 2023
REVOM: Real-time Volume Measurement in Blood Culture Sampling

VINNOVA

1 June 2020 - 31 May 2022
IDx: An exploration of regulatory, corporate, relational, and technical barriers to uptake of diagnostics in the fight against AMR

Swedish Research Council

1 December 2019 - 31 December 2021

Anställningar

Adjungerad Professor, Laboratoriemedicin, Karolinska Institutet, 2022-2025

Examina och utbildning

Docent, Klinisk mikrobiologi, Karolinska Institutet, 2010
MEDICINE DOKTORSEXAMEN, Institutionen för neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2000

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