Ulf Hedin

Om mig
Publikationer
Populärvetenskap och samverkan

Om mig

Forskargruppsledare för gruppen Kärlkirurgi.

Artiklar

Article: CARDIOVASCULAR RESEARCH. 2023;119(7):1524-1536

Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk.

Forteza MJ; Berg M; Edsfeldt A; Sun J; Baumgartner R; Kareinen I; Casagrande FB; Hedin U; Zhang S; Vuckovic I; Dzeja PP; Polyzos KA; Gisterå A; Trauelsen M; Schwartz TW; Dib L; Herrmann J; Monaco C; Matic L; Gonçalves I; Ketelhuth DFJ
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2023;65(6):778-786

Long Term Mortality Rate in Patients Treated with Carotid Endarterectomy.

Wadén K; Hultgren R; Kotopouli MI; Gillgren P; Roy J; Hedin U; Matic L
Article: CIRCULATION RESEARCH. 2023;132(9):1144-1161

FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells.

Wong D; Auguste G; Lino Cardenas CL; Turner AW; Chen Y; Song Y; Ma L; Perry RN; Aherrahrou R; Kuppusamy M; Yang C; Mosquera JV; Dube CJ; Khan MD; Palmore M; Kalra J; Kavousi M; Peyser PA; Matic L; Hedin U; Manichaikul A; Sonkusare SK; Civelek M; Kovacic JC; Björkegren JLM; Malhotra R; Miller CL
Article: ATHEROSCLEROSIS. 2023;371:41-53

Interleukin-6 trans-signaling induced laminin switch contributes to reduced trans-endothelial migration of granulocytic cells.

Zegeye MM; Matic L; Lengquist M; Hayderi A; Grenegård M; Hedin U; Sirsjö A; Ljungberg LU; Kumawat AK
Article: COMPUTERS IN BIOLOGY AND MEDICINE. 2023;152:106364

In silico model of atherosclerosis with individual patient calibration to enable precision medicine for cardiovascular disease.

Buckler AJ; Marlevi D; Skenteris NT; Lengquist M; Kronqvist M; Matic L; Hedin U
Article: CELLS. 2022;11(20):3279

Biomechanical Assessment of Macro-Calcification in Human Carotid Atherosclerosis and Its Impact on Smooth Muscle Cell Phenotype.

Seime T; van Wanrooij M; Karlöf E; Kronqvist M; Johansson S; Matic L; Gasser TC; Hedin U
Article: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2022;134:105403

Patient-specific biomechanical analysis of atherosclerotic plaques enabled by histologically validated tissue characterization from computed tomography angiography: A case study.

Buckler AJ; van Wanrooij M; Andersson M; Karlöf E; Matic LP; Hedin U; Gasser TC
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2022;37(9):1742-1750

Surgical versus endovascular intervention for vascular access thrombosis: a nationwide observational cohort study.

Lundström UH; Welander G; Carrero JJ; Hedin U; Evans M
Article: ISCIENCE. 2022;25(5):104219

Clinical risk scores for stroke correlate with molecular signatures of vulnerability in symptomatic carotid patients.

Wadén K; Karlöf E; Narayanan S; Lengquist M; Hansson GK; Hedin U; Roy J; Matic L
Article: ATHEROSCLEROSIS. 2022;348:8-15

A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease.

Dang A-T; Turner AW; Lau P; Mohottalage D; Stephanie Fong YK; Eriksson P; Folkersen L; Matic L; Hedin U; Soubeyrand S; McPherson R
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2022;42(5):659-676

Plaque Evaluation by Ultrasound and Transcriptomics Reveals BCLAF1 as a Regulator of Smooth Muscle Cell Lipid Transdifferentiation in Atherosclerosis.

Rykaczewska U; Zhao Q; Saliba-Gustafsson P; Lengquist M; Kronqvist M; Bergman O; Huang Z; Lund K; Waden K; Pons Vila Z; Caidahl K; Skogsberg J; Vukojevic V; Lindeman JHN; Roy J; Hansson GK; Treuter E; Leeper NJ; Eriksson P; Ehrenborg E; Razuvaev A; Hedin U; Matic L
Article: CARDIOVASCULAR RESEARCH. 2022;118(5):1232-1246

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling.

van Kuijk K; Demandt JAF; Perales-Patón J; Theelen TL; Kuppe C; Marsch E; de Bruijn J; Jin H; Gijbels MJ; Matic L; Mees BME; Reutelingsperger CPM; Hedin U; Biessen EAL; Carmeliet P; Baker AH; Kramann RK; Schurgers LJ; Saez-Rodriguez J; Sluimer JC
Article: DIABETES. 2022;71(2):285-297

Downregulation of Erythrocyte miR-210 Induces Endothelial Dysfunction in Type 2 Diabetes.

Zhou Z; Collado A; Sun C; Tratsiakovich Y; Mahdi A; Winter H; Chernogubova E; Seime T; Narayanan S; Jiao T; Jin H; Alvarsson M; Zheng X; Yang J; Hedin U; Catrina S-B; Maegdefessel L; Pernow J
Article: FRONTIERS IN PHARMACOLOGY. 2022;13:988561

Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease.

Suur BE; Chemaly M; Lindquist Liljeqvist M; Djordjevic D; Stenemo M; Bergman O; Karlöf E; Lengquist M; Odeberg J; Hurt-Camejo E; Eriksson P; Ketelhuth DFJ; Roy J; Hedin U; Nyberg M; Matic L
Article: CARDIOVASCULAR RESEARCH. 2021;117(14):2767-2780

Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability.

Tsantilas P; Lao S; Wu Z; Eberhard A; Winski G; Vaerst M; Nanda V; Wang Y; Kojima Y; Ye J; Flores A; Jarr K-U; Pelisek J; Eckstein H-H; Matic L; Hedin U; Tsao PS; Paloschi V; Maegdefessel L; Leeper NJ
Article: CIRCULATION. 2021;144(19):1567-1583

Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization.

Fasolo F; Jin H; Winski G; Chernogubova E; Pauli J; Winter H; Li DY; Glukha N; Bauer S; Metschl S; Wu Z; Koschinsky ML; Reilly M; Pelisek J; Kempf W; Eckstein H-H; Soehnlein O; Matic L; Hedin U; Bäcklund A; Bergmark C; Paloschi V; Maegdefessel L
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2021;62(5):716-726

Carotid Plaque Phenotyping by Correlating Plaque Morphology from Computed Tomography Angiography with Transcriptional Profiling.

Karlöf E; Buckler A; Liljeqvist ML; Lengquist M; Kronqvist M; Toonsi MA; Maegdefessel L; Matic LP; Hedin U
Article: CLINICAL AND TRANSLATIONAL MEDICINE. 2021;11(6):e458

Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage.

Jin H; Goossens P; Juhasz P; Eijgelaar W; Manca M; Karel JMH; Smirnov E; Sikkink CJJM; Mees BME; Waring O; van Kuijk K; Fazzi GE; Gijbels MJJ; Kutmon M; Evelo CTA; Hedin U; Daemen MJAP; Sluimer JC; Matic L; Biessen EAL
Article: CELLS. 2021;10(6):1276

Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification.

Seime T; Akbulut AC; Liljeqvist ML; Siika A; Jin H; Winski G; van Gorp RH; Karlöf E; Lengquist M; Buckler AJ; Kronqvist M; Waring OJ; Lindeman JHN; Biessen EAL; Maegdefessel L; Razuvaev A; Schurgers LJ; Hedin U; Matic L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(5):1738-1750

Virtual Transcriptomics: Noninvasive Phenotyping of Atherosclerosis by Decoding Plaque Biology From Computed Tomography Angiography Imaging.

Buckler AJ; Karlöf E; Lengquist M; Gasser TC; Maegdefessel L; Perisic Matic L; Hedin U
Article: VASCULAR MEDICINE. 2021;26(1):3-10

Expression of Interleukin 6 signaling receptors in carotid atherosclerosis.

Ziegler L; Lundqvist J; Dreij K; Wallén H; de Faire U; Paulsson-Berne G; Hedin U; Matic L; Gigante B
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2021;36(2):275-280

Arteriovenous access placement and renal function decline.

Hahn Lundström U; Hedin U; Gasparini A; Caskey FJ; Carrero J-J; Evans M
Article: CIRCULATION. 2021;143(2):163-177

RIPK1 Expression Associates With Inflammation in Early Atherosclerosis in Humans and Can Be Therapeutically Silenced to Reduce NF-κB Activation and Atherogenesis in Mice.

Karunakaran D; Nguyen M-A; Geoffrion M; Vreeken D; Lister Z; Cheng HS; Otte N; Essebier P; Wyatt H; Kandiah JW; Jung R; Alenghat FJ; Mompeon A; Lee R; Pan C; Gordon E; Rasheed A; Lusis AJ; Liu P; Matic LP; Hedin U; Fish JE; Guo L; Kolodgie F; Virmani R; van Gils JM; Rayner KJ
Article: CEREBROVASCULAR DISEASES. 2021;50(1):108-120

Multinational Survey of Current Practice from Imaging to Treatment of Atherosclerotic Carotid Stenosis.

Saba L; Mossa-Basha M; Abbott A; Lanzino G; Wardlaw JM; Hatsukami TS; Micheletti G; Balestrieri A; Hedin U; Moody AR; Wintermark M; DeMarco JK
Article: JOURNAL OF INTERNAL MEDICINE. 2021;289(1):53-68

Evidence that a deviation in the kynurenine pathway aggravates atherosclerotic disease in humans.

Baumgartner R; Berg M; Matic L; Polyzos KP; Forteza MJ; Hjorth SA; Schwartz TW; Paulsson-Berne G; Hansson GK; Hedin U; Ketelhuth DFJ
Article: JVS-VASCULAR SCIENCE. 2021;2:72-78

Resolving the biological paradox of aneurysm formation in children with tuberous sclerosis complex.

Hedin U; Brunnström H; Dahlin M; Backman T; Perez de Sa V; Tran P-K
Journal article: CIRCULATION. 2021;144(19):1567-1583

Long Noncoding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization

Fasolo F; Jin H; Winski G; Chernogubova E; Pauli J; Winter H; Li DYY; Glukha N; Bauer S; Metschl S; Wu Z; Koschinsky ML; Reilly M; Pelisek J; Kempf W; Eckstein H-H; Soehnlein O; Matic L; Hedin U; Backlund A; Bergmark C; Paloschi V; Maegdefessel L
Article: ATHEROSCLEROSIS. 2020;314:1-9

A neutralizing antibody against DKK1 does not reduce plaque formation in classical murine models of atherosclerosis: Is the therapeutic potential lost in translation?

Rakipovski G; Rolin B; Barascuk N; Lund HE; Bjørn Bonde MF; Djordjevic D; Wulff-Larsen PG; Petersen M; Kirk RK; Hultman K; Manfe V; Blume N; Zahn S; Lengquist M; Maegdefessel L; Hovingh GK; Conde-Knape K; Hedin U; Matic L; Nyberg M
Article: JOURNAL OF INFECTIOUS DISEASES. 2020;222(12):2041-2051

Induction of the Coxsackievirus and Adenovirus Receptor in Macrophages During the Formation of Atherosclerotic Plaques.

Nilchian A; Plant E; Parniewska MM; Santiago A; Rossignoli A; Skogsberg J; Hedin U; Matic L; Fuxe J
Article: SCIENTIFIC REPORTS. 2020;10(1):19108

Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells.

Paramel GV; Karadimou G; Eremo AG; Ljungberg LU; Hedin U; Olofsson PS; Folkersen L; Paulsson-Berne G; Sirsjö A; Fransén K
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2020;235(10):7370-7382

Antagonistic relationship between the unfolded protein response and myocardin-driven transcription in smooth muscle.

Zhu B; Daoud F; Zeng S; Matic L; Hedin U; Uvelius B; Rippe C; Albinsson S; Swärd K
Article: CIRCULATION RESEARCH. 2020;127(7):911-927

Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification.

Furmanik M; Chatrou M; van Gorp R; Akbulut A; Willems B; Schmidt H; van Eys G; Bochaton-Piallat M-L; Proudfoot D; Biessen E; Hedin U; Perisic L; Mees B; Shanahan C; Reutelingsperger C; Schurgers L
Article: CELLS. 2020;9(4):E1009-1009

Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice.

Röhl S; Suur BE; Lengquist M; Seime T; Caidahl K; Hedin U; Arner A; Matic L; Razuvaev A
Article: CIRCULATION RESEARCH. 2020;126(5):571-585

PCSK6 Is a Key Protease in the Control of Smooth Muscle Cell Function in Vascular Remodeling.

Rykaczewska U; Suur BE; Röhl S; Razuvaev A; Lengquist M; Sabater-Lleal M; van der Laan SW; Miller CL; Wirka RC; Kronqvist M; Gonzalez Diez M; Vesterlund M; Gillgren P; Odeberg J; Lindeman JH; Veglia F; Humphries SE; de Faire U; Baldassarre D; Tremoli E; IMPROVE study group; Lehtiö J; Hansson GK; Paulsson-Berne G; Pasterkamp G; Quertermous T; Hamsten A; Eriksson P; Hedin U; Matic L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2020;40(2):412-425

MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice.

Cheng J; Cheng A; Clifford BL; Wu X; Hedin U; Maegdefessel L; Pamir N; Sallam T; Tarling EJ; de Aguiar Vallim TQ
Article: ATHEROSCLEROSIS. 2020;292:215-223

Endothelin-1 increases expression and activity of arginase 2 via ETB receptors and is co-expressed with arginase 2 in human atherosclerotic plaques.

Rafnsson A; Matic LP; Lengquist M; Mahdi A; Shemyakin A; Paulsson-Berne G; Hansson GK; Gabrielsen A; Hedin U; Yang J; Pernow J
Article: PLOS GENETICS. 2020;16(1):e1008538

Genomic profiling of human vascular cells identifies TWIST1 as a causal gene for common vascular diseases.

Nurnberg ST; Guerraty MA; Wirka RC; Rao HS; Pjanic M; Norton S; Serrano F; Perisic L; Elwyn S; Pluta J; Zhao W; Testa S; Park Y; Nguyen T; Ko Y-A; Wang T; Hedin U; Sinha S; Barash Y; Brown CD; Quertermous T; Rader DJ
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:619079

Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function.

Pham TP; Bink DI; Stanicek L; van Bergen A; van Leeuwen E; Tran Y; Matic L; Hedin U; Wittig I; Dimmeler S; Boon RA
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2020;15:6137-6152

Molecular Imaging of Inflammation in a Mouse Model of Atherosclerosis Using a Zirconium-89-Labeled Probe.

Ahmed M; Tegnebratt T; Tran TA; Lu L; Damberg P; Gisterå A; Tarnawski L; Bone D; Hedin U; Eriksson P; Holmin S; Gustafsson B; Caidahl K
Article: JVS-VASCULAR SCIENCE. 2020;1:13-27

Transcriptomic profiling of experimental arterial injury reveals new mechanisms and temporal dynamics in vascular healing response.

Röhl S; Rykaczewska U; Seime T; Suur BE; Diez MG; Gådin JR; Gainullina A; Sergushichev AA; Wirka R; Lengquist M; Kronqvist M; Bergman O; Odeberg J; Lindeman JHN; Quertermous T; Hamsten A; Eriksson P; Hedin U; Razuvaev A; Matic LP
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2019;317(6):C1128-C1142

Identification of the intermediate filament protein synemin/SYNM as a target of myocardin family coactivators.

Swärd K; Krawczyk KK; Morén B; Zhu B; Matic L; Holmberg J; Hedin U; Uvelius B; Stenkula K; Rippe C
Article: THROMBOSIS AND HAEMOSTASIS. 2019;119(12):2014-2024

Early Inhibition of P-Selectin/P-Selectin Glycoprotein Ligand-1 Reduces Intimal Hyperplasia in Murine Vein Grafts through Platelet Adhesion.

Tseng C-N; Chang Y-T; Yen C-Y; Lengquist M; Kronqvist M; Eriksson EE; Hedin U
Article: ATHEROSCLEROSIS. 2019;288:175-185

Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization.

Karlöf E; Seime T; Dias N; Lengquist M; Witasp A; Almqvist H; Kronqvist M; Gådin JR; Odeberg J; Maegdefessel L; Stenvinkel P; Matic LP; Hedin U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(33):16410-16419

Regulation of CCL2 expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA.

Khyzha N; Khor M; DiStefano PV; Wang L; Matic L; Hedin U; Wilson MD; Maegdefessel L; Fish JE
Article: JOURNAL OF ULTRASOUND IN MEDICINE. 2019;38(7):1723-1731

Noninvasive in vivo Assessment of the Re-endothelialization Process Using Ultrasound Biomicroscopy in the Rat Carotid Artery Balloon Injury Model.

Röhl S; Eriksson L; Saxelin R; Lengquist M; Östenson C-G; Hedin U; Caidahl K; Razuvaev A
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2019;4(3):304-317

Inflammasome-Driven Interleukin-1α and Interleukin-1β Production in Atherosclerotic Plaques Relates to Hyperlipidemia and Plaque Complexity.

Jiang X; Wang F; Wang Y; Gisterå A; Roy J; Paulsson-Berne G; Hedin U; Lerman A; Hansson GK; Herrmann J; Yan Z-Q
Article: CIRCULATION. 2019;139(21):2466-2482

Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability.

Centa M; Jin H; Hofste L; Hellberg S; Busch A; Baumgartner R; Verzaal NJ; Lind Enoksson S; Perisic Matic L; Boddul SV; Atzler D; Li DY; Sun C; Hansson GK; Ketelhuth DFJ; Hedin U; Wermeling F; Lutgens E; Binder CJ; Maegdesfessel L; Malin SG
Article: ATHEROSCLEROSIS. 2019;283:127-136

Dual roles of heparanase in human carotid plaque calcification.

Aldi S; Eriksson L; Kronqvist M; Lengquist M; Löfling M; Folkersen L; Matic LP; Maegdefessel L; Grinnemo K-H; Li J-P; Österholm C; Hedin U
Article: CIRCULATION. 2019;139(10):1320-1334

Hematopoietic Deficiency of the Long Noncoding RNA MALAT1 Promotes Atherosclerosis and Plaque Inflammation.

Cremer S; Michalik KM; Fischer A; Pfisterer L; Jaé N; Winter C; Boon RA; Muhly-Reinholz M; John D; Uchida S; Weber C; Poller W; Günther S; Braun T; Li DY; Maegdefessel L; Perisic Matic L; Hedin U; Soehnlein O; Zeiher A; Dimmeler S
Article: CELLULAR AND MOLECULAR BIOENGINEERING. 2019;12(1):15-32

Molecular Imaging of a New Multimodal Microbubble for Adhesion Molecule Targeting.

Ahmed M; Gustafsson B; Aldi S; Dusart P; Egri G; Butler LM; Bone D; Dähne L; Hedin U; Caidahl K
Article: EUROPEAN HEART JOURNAL. 2019;40(4):372-382

Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8+ T cell-mediated macrophage death.

Seijkens TTP; Poels K; Meiler S; van Tiel CM; Kusters PJH; Reiche M; Atzler D; Winkels H; Tjwa M; Poelman H; Slütter B; Kuiper J; Gijbels M; Kuivenhoven JA; Matic LP; Paulsson-Berne G; Hedin U; Hansson GK; Nicolaes GAF; Daemen MJAP; Weber C; Gerdes N; de Winther MPJ; Lutgens E
Article: PLOS ONE. 2019;14(8):e0221477

Oncostatin M reduces atherosclerosis development in APOE*3Leiden.CETP mice and is associated with increased survival probability in humans.

Keulen DV; Pouwer MG; Emilsson V; Matic LP; Pieterman EJ; Hedin U; Gudnason V; Jennings LL; Holmstrøm K; Nielsen BS; Pasterkamp G; Lindeman JHN; van Gool AJ; Sollewijn Gelpke MD; Princen HMG; Tempel D
Article: NATURE METABOLISM. 2019;1(1):98-110

The long noncoding RNA CHROME regulates cholesterol homeostasis in primate.

Hennessy EJ; van Solingen C; Scacalossi KR; Ouimet M; Afonso MS; Prins J; Koelwyn GJ; Sharma M; Ramkhelawon B; Carpenter S; Busch A; Chernogubova E; Matic LP; Hedin U; Maegdefessel L; Caffrey BE; Hussein MA; Ricci EP; Temel RE; Garabedian MJ; Berger JS; Vickers KC; Kanke M; Sethupathy P; Teupser D; Holdt LM; Moore KJ
Article: CARDIOVASCULAR RESEARCH. 2019;115(1):230-242

Long non-coding RNA H19 regulates endothelial cell aging via inhibition of STAT3 signalling.

Hofmann P; Sommer J; Theodorou K; Kirchhof L; Fischer A; Li Y; Perisic L; Hedin U; Maegdefessel L; Dimmeler S; Boon RA
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2019;14:3723-3741

Human serum albumin-based probes for molecular targeting of macrophage scavenger receptors.

Ahmed M; Baumgartner R; Aldi S; Dusart P; Hedin U; Gustafsson B; Caidahl K
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2018;315(6):c873-c884

Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics.

Krawczyk KK; Skovsted GF; Perisic L; Dreier R; Berg JO; Hedin U; Rippe C; Swärd K
Article: PLOS GENETICS. 2018;14(11):e1007755

Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus.

Nanda V; Wang T; Pjanic M; Liu B; Nguyen T; Matic LP; Hedin U; Koplev S; Ma L; Franzén O; Ruusalepp A; Schadt EE; Björkegren JLM; Montgomery SB; Snyder MP; Quertermous T; Leeper NJ; Miller CL
Article: JOURNAL OF VASCULAR ACCESS. 2018;19(6):535-541

Haemodialysis access thrombosis: Outcomes after surgical thrombectomy versus catheter-directed thrombolytic infusion.

Koraen-Smith L; Krasun M; Bottai M; Hedin U; Wahlgren CM; Gillgren P
Article: SCIENTIFIC REPORTS. 2018;8(1):14668

A systems-approach reveals human nestin is an endothelial-enriched, angiogenesis-independent intermediate filament protein.

Dusart P; Fagerberg L; Perisic L; Civelek M; Struck E; Hedin U; Uhlén M; Trégouët D-A; Renné T; Odeberg J; Butler LM
Article: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT. 2018;10:17-28

Integrated Human Evaluation of the Lysophosphatidic Acid Pathway as a Novel Therapeutic Target in Atherosclerosis.

Aldi S; Matic LP; Hamm G; van Keulen D; Tempel D; Holmstrøm K; Szwajda A; Nielsen BS; Emilsson V; Ait-Belkacem R; Lengquist M; Paulsson-Berne G; Eriksson P; Lindeman JHN; Gool AJ; Stauber J; Hedin U; Hurt-Camejo E
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2018;11(9):e002115

Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques.

van der Laan SW; Siemelink MA; Haitjema S; Foroughi Asl H; Perisic L; Mokry M; van Setten J; Malik R; Dichgans M; Worrall BB; METASTROKE Collaboration of the International Stro; Samani NJ; Schunkert H; Erdmann J; Hedin U; Paulsson-Berne G; Björkegrenn JLM; de Borst GJ; Asselbergs FW; den Ruijter FW; de Bakker PIW; Pasterkamp G
Article: SCIENTIFIC REPORTS. 2018;8(1):13025

Nexilin/NEXN controls actin polymerization in smooth muscle and is regulated by myocardin family coactivators and YAP.

Zhu B; Rippe C; Holmberg J; Zeng S; Perisic L; Albinsson S; Hedin U; Uvelius B; Swärd K
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2018;72(7):769-780

Erythrocytes From Patients With Type 2 Diabetes Induce Endothelial Dysfunction Via Arginase I.

Zhou Z; Mahdi A; Tratsiakovich Y; Zahorán S; Kövamees O; Nordin F; Uribe Gonzalez AE; Alvarsson M; Östenson C-G; Andersson DC; Hedin U; Hermesz E; Lundberg JO; Yang J; Pernow J
Article: JACC-BASIC TO TRANSLATIONAL SCIENCE. 2018;3(4):464-480

Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage.

Matic LP; Jesus Iglesias M; Vesterlund M; Lengquist M; Hong M-G; Saieed S; Sanchez-Rivera L; Berg M; Razuvaev A; Kronqvist M; Lund K; Caidahl K; Gillgren P; Pontén F; Uhlén M; Schwenk JM; Hansson GK; Paulsson-Berne G; Fagman E; Roy J; Hultgren R; Bergström G; Lehtiö J; Odeberg J; Hedin U
Article: EUROPEAN HEART JOURNAL. 2018;39(24):2301-2310

Altered metabolism distinguishes high-risk from stable carotid atherosclerotic plaques.

Tomas L; Edsfeldt A; Mollet IG; Perisic Matic L; Prehn C; Adamski J; Paulsson-Berne G; Hedin U; Nilsson J; Bengtsson E; Gonçalves I; Björkbacka H
Article: MOLECULAR THERAPY. 2018;26(4):1040-1055

Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.

Jin H; Li DY; Chernogubova E; Sun C; Busch A; Eken SM; Saliba-Gustafsson P; Winter H; Winski G; Raaz U; Schellinger IN; Simon N; Hegenloh R; Matic LP; Jagodic M; Ehrenborg E; Pelisek J; Eckstein H-H; Hedin U; Backlund A; Maegdefessel L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2018;38(1):49-63

Extracellular Vesicles Secreted by Atherogenic Macrophages Transfer MicroRNA to Inhibit Cell Migration.

Nguyen M-A; Karunakaran D; Geoffrion M; Cheng HS; Tandoc K; Perisic Matic L; Hedin U; Maegdefessel L; Fish JE; Rayner KJ
Article: CIRCULATION JOURNAL. 2017;81(12):1945-1952

Increased Carotid Artery Lesion Inflammation Upon Treatment With the CD137 Agonistic Antibody 2A.

Söderström LÅ; Jin H; Caravaca AS; Klement ML; Li Y; Gisterå A; Hedin U; Maegdefessel L; Hansson GK; Olofsson PS
Article: JOURNAL OF INTERNAL MEDICINE. 2017;282(5):429-444

Integrative studies implicate matrix metalloproteinase-12 as a culprit gene for large-artery atherosclerotic stroke.

Mahdessian H; Perisic Matic L; Lengquist M; Gertow K; Sennblad B; Baldassarre D; Veglia F; Humphries SE; Rauramaa R; de Faire U; Smit AJ; Giral P; Kurl S; Mannarino E; Tremoli E; Hamsten A; Eriksson P; Hedin U; Mälarstig A; IMPROVE study group
Article: PLOS GENETICS. 2017;13(5):e1006750

TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells.

Kim JB; Pjanic M; Nguyen T; Miller CL; Iyer D; Liu B; Wang T; Sazonova O; Carcamo-Orive I; Matic LP; Maegdefessel L; Hedin U; Quertermous T
Article: JOURNAL OF CLINICAL INVESTIGATION. 2017;127(4):1546-1560

Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques.

Langley SR; Willeit K; Didangelos A; Matic LP; Skroblin P; Barallobre-Barreiro J; Lengquist M; Rungger G; Kapustin A; Kedenko L; Molenaar C; Lu R; Barwari T; Suna G; Yin X; Iglseder B; Paulweber B; Willeit P; Shalhoub J; Pasterkamp G; Davies AH; Monaco C; Hedin U; Shanahan CM; Willeit J; Kiechl S; Mayr M
Article: JOURNAL OF INTERNAL MEDICINE. 2017;281(4):383-397

Vaccination against T-cell epitopes of native ApoB100 reduces vascular inflammation and disease in a humanized mouse model of atherosclerosis.

Gisterå A; Hermansson A; Strodthoff D; Klement ML; Hedin U; Fredrikson GN; Nilsson J; Hansson GK; Ketelhuth DFJ
Article: JOURNAL OF VASCULAR ACCESS. 2017;18(Suppl. 1):110-113

Upper-arm hemodialysis access in Sweden.

Hedin U; Welander G
Article: CIRCULATION RESEARCH. 2017;120(4):633-644

MicroRNA-210 Enhances Fibrous Cap Stability in Advanced Atherosclerotic Lesions.

Eken SM; Jin H; Chernogubova E; Li Y; Simon N; Sun C; Korzunowicz G; Busch A; Bäcklund A; Österholm C; Razuvaev A; Renné T; Eckstein HH; Pelisek J; Eriksson P; González Díez M; Perisic Matic L; Schellinger IN; Raaz U; Leeper NJ; Hansson GK; Paulsson-Berne G; Hedin U; Maegdefessel L
Article: NATURE MEDICINE. 2016;22(10):1140-1150

Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation.

Stellos K; Gatsiou A; Stamatelopoulos K; Perisic Matic L; John D; Lunella FF; Jaé N; Rossbach O; Amrhein C; Sigala F; Boon RA; Fürtig B; Manavski Y; You X; Uchida S; Keller T; Boeckel J-N; Franco-Cereceda A; Maegdefessel L; Chen W; Schwalbe H; Bindereif A; Eriksson P; Hedin U; Zeiher AM; Dimmeler S
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(9):1947-1961

Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM.

Perisic Matic L; Rykaczewska U; Razuvaev A; Sabater-Lleal M; Lengquist M; Miller CL; Ericsson I; Röhl S; Kronqvist M; Aldi S; Magné J; Paloschi V; Vesterlund M; Li Y; Jin H; Diez MG; Roy J; Baldassarre D; Veglia F; Humphries SE; de Faire U; Tremoli E; Odeberg J; Vukojević V; Lehtiö J; Maegdefessel L; Ehrenborg E; Paulsson-Berne G; Hansson GK; Lindeman JHN; Eriksson P; Quertermous T; Hamsten A; Hedin U
Article: PULMONARY CIRCULATION. 2016;6(3):347-359

Versican accumulates in vascular lesions in pulmonary arterial hypertension.

Chang Y-T; Chan CK; Eriksson I; Johnson PY; Cao X; Westöö C; Norvik C; Andersson-Sjöland A; Westergren-Thorsson G; Johansson S; Hedin U; Kjellén L; Wight TN; Tran-Lundmark K
Article: NATURE. 2016;536(7614):86-90

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis.

Kojima Y; Volkmer J-P; McKenna K; Civelek M; Lusis AJ; Miller CL; Direnzo D; Nanda V; Ye J; Connolly AJ; Schadt EE; Quertermous T; Betancur P; Maegdefessel L; Matic LP; Hedin U; Weissman IL; Leeper NJ
Article: NATURE COMMUNICATIONS. 2016;7:12092

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci.

Miller CL; Pjanic M; Wang T; Nguyen T; Cohain A; Lee JD; Perisic L; Hedin U; Kundu RK; Majmudar D; Kim JB; Wang O; Betsholtz C; Ruusalepp A; Franzén O; Assimes TL; Montgomery SB; Schadt EE; Björkegren JLM; Quertermous T
Article: SCIENCE ADVANCES. 2016;2(7):e1600224

Targeting macrophage necroptosis for therapeutic and diagnostic interventions in atherosclerosis.

Karunakaran D; Geoffrion M; Wei L; Gan W; Richards L; Shangari P; DeKemp EM; Beanlands RA; Perisic L; Maegdefessel L; Hedin U; Sad S; Guo L; Kolodgie FD; Virmani R; Ruddy T; Rayner KJ
Article: ONCOTARGET. 2016;7(26):39486-39496

Heparanase expression upregulates platelet adhesion activity and thrombogenicity.

Cui H; Tan Y-X; Österholm C; Zhang X; Hedin U; Vlodavsky I; Li J-P
Article: SCIENTIFIC REPORTS. 2016;6:28337

Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.

Skarpengland T; Holm S; Scheffler K; Gregersen I; Dahl TB; Suganthan R; Segers FM; Østlie I; Otten JJT; Luna L; Ketelhuth DFJ; Lundberg AM; Neurauter CG; Hildrestrand G; Skjelland M; Bjørndal B; Svardal AM; Iversen PO; Hedin U; Nygård S; Olstad OK; Krohg-Sørensen K; Slupphaug G; Eide L; Kuśnierczyk A; Folkersen L; Ueland T; Berge RK; Hansson GK; Biessen EAL; Halvorsen B; Bjørås M; Aukrust P
Article: JOURNAL OF THE AMERICAN HEART ASSOCIATION. 2016;5(5):e003031

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis.

Paramel Varghese G; Folkersen L; Strawbridge RJ; Halvorsen B; Yndestad A; Ranheim T; Krohg-Sørensen K; Skjelland M; Espevik T; Aukrust P; Lengquist M; Hedin U; Jansson J-H; Fransén K; Hansson GK; Eriksson P; Sirsjö A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):972-983

Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease.

Turner AW; Martinuk A; Silva A; Lau P; Nikpay M; Eriksson P; Folkersen L; Perisic L; Hedin U; Soubeyrand S; McPherson R
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2016;36(5):942-951

miRNA Targeting of Oxysterol-Binding Protein-Like 6 Regulates Cholesterol Trafficking and Efflux.

Ouimet M; Hennessy EJ; van Solingen C; Koelwyn GJ; Hussein MA; Ramkhelawon B; Rayner KJ; Temel RE; Perisic L; Hedin U; Maegdefessel L; Garabedian MJ; Holdt LM; Teupser D; Moore KJ
Article: JOURNAL OF INTERNAL MEDICINE. 2016;279(3):293-308

Gene expression signatures, pathways and networks in carotid atherosclerosis.

Perisic L; Aldi S; Sun Y; Folkersen L; Razuvaev A; Roy J; Lengquist M; Åkesson S; Wheelock CE; Maegdefessel L; Gabrielsen A; Odeberg J; Hansson GK; Paulsson-Berne G; Hedin U
Article: CIRCULATION RESEARCH. 2016;118(2):230-240

CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels.

Nanda V; Downing KP; Ye J; Xiao S; Kojima Y; Spin JM; DiRenzo D; Nead KT; Connolly AJ; Dandona S; Perisic L; Hedin U; Maegdefessel L; Dalman J; Guo L; Zhao X; Kolodgie FD; Virmani R; Davis HR; Leeper NJ
Article: GENOMICS DATA. 2015;5:36-37

Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells that Contribute to the Fibrous Cap.

Nurnberg ST; Cheng K; Raiesdana A; Kundu R; Miller CL; Kim JB; Arora K; Carcamo-Oribe I; Xiong Y; Tellakula N; Nanda V; Murthy N; Boisvert WA; Hedin U; Perisic L; Aldi S; Maegdefessel L; Pjanic M; Owens GK; Tallquist MD; Quertermous T
Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2015;56(4):599-605

Endovascular treatment of true and false aneurysms in hemodialysis access.

Hedin U; Engström J; Roy J
Article: CIRCULATION RESEARCH. 2015;117(3):266-278

Macrophage Mitochondrial Energy Status Regulates Cholesterol Efflux and Is Enhanced by Anti-miR33 in Atherosclerosis.

Karunakaran D; Thrush AB; Nguyen M-A; Richards L; Geoffrion M; Singaravelu R; Ramphos E; Shangari P; Ouimet M; Pezacki JP; Moore KJ; Perisic L; Maegdefessel L; Hedin U; Harper M-E; Rayner KJ
Article: CARDIOVASCULAR RESEARCH. 2015;107(1):20-31

Perlecan heparan sulfate deficiency impairs pulmonary vascular development and attenuates hypoxic pulmonary hypertension.

Chang Y-T; Tseng C-N; Tannenberg P; Eriksson L; Yuan K; de Jesus Perez VA; Lundberg J; Lengquist M; Botusan IR; Catrina S-B; Tran P-K; Hedin U; Tran-Lundmark K
Article: PLOS GENETICS. 2015;11(5):e1005155

Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap.

Nurnberg ST; Cheng K; Raiesdana A; Kundu R; Miller CL; Kim JB; Arora K; Carcamo-Oribe I; Xiong Y; Tellakula N; Nanda V; Murthy N; Boisvert WA; Hedin U; Perisic L; Aldi S; Maegdefessel L; Pjanic M; Owens GK; Tallquist MD; Quertermous T
Article: THROMBOSIS AND HAEMOSTASIS. 2015;113(4):813-825

Platelet adhesion on endothelium early after vein grafting mediates leukocyte recruitment and intimal hyperplasia in a murine model.

Tseng C-N; Chang Y-T; Lengquist M; Kronqvist M; Hedin U; Eriksson EE
Article: THROMBOSIS RESEARCH. 2015;135(3):443-448

Preoperative hypofibrinogenemia is associated with increased intraoperative bleeding in ruptured abdominal aortic aneurysms.

Montán C; Johansson F; Hedin U; Wahlgren CM
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2015;230(2):482-487

Perlecan Heparan Sulfate Is Required for the Inhibition of Smooth Muscle Cell Proliferation by All-trans-Retinoic Acid.

Tran-Lundmark K; Tannenberg P; Rauch BH; Ekstrand J; Tran P-K; Hedin U; Kinsella MG
Article: JOURNAL OF VASCULAR RESEARCH. 2015;52(1):41-52

Glucagon-Like Peptide-1 Receptor Activation Does not Affect Re-Endothelialization but Reduces Intimal Hyperplasia via Direct Effects on Smooth Muscle Cells in a Nondiabetic Model of Arterial Injury.

Eriksson L; Saxelin R; Röhl S; Roy J; Caidahl K; Nyström T; Hedin U; Razuvaev A
Article: CONTRAST MEDIA & MOLECULAR IMAGING. 2015;10(1):37-42

Glycolaldehyde and maleyl conjugated human serum albumin as potential macrophage-targeting carriers for molecular imaging purposes.

Gustafsson B; Hedin U; Caidahl K
Article: PLOS ONE. 2015;10(3):e0122067

Schip1 is a novel podocyte foot process protein that mediates actin cytoskeleton rearrangements and forms a complex with Nherf2 and ezrin.

Perisic L; Rodriguez PQ; Hultenby K; Sun Y; Lal M; Betsholtz C; Uhlén M; Wernerson A; Hedin U; Pikkarainen T; Tryggvason K; Patrakka J
Article: JOURNAL OF VASCULAR ACCESS. 2015;16 Suppl 9:S87-S92

Long-term results of PTFE grafts.

Hedin U
Article: JOURNAL OF CARDIOVASCULAR SURGERY. 2014;55(6):793-801

Vascular access: a never-ending story.

Hedin U
Article: JOURNAL OF INTERNAL MEDICINE. 2014;276(5):525-536

The collagen cross-linking enzyme lysyl oxidase is associated with the healing of human atherosclerotic lesions.

Ovchinnikova OA; Folkersen L; Persson J; Lindeman JHN; Ueland T; Aukrust P; Gavrisheva N; Shlyakhto E; Paulsson-Berne G; Hedin U; Olofsson PS; Hansson GK
Article: CANADIAN JOURNAL OF CARDIOLOGY. 2014;30(11):1444-1451

Perlecan heparan sulfate proteoglycan is a critical determinant of angiogenesis in response to mouse hind-limb ischemia.

Qiang B; Lim SY; Lekas M; Kuliszewski MA; Wolff R; Osherov AB; Rudenko D; Leong-Poi H; Noyan H; Husain M; Tran K; Tryggvason K; Hedin U; Tran-Lundmark K; Strauss BH
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2014;44(10):3081-3092

Innate immune receptor NOD2 promotes vascular inflammation and formation of lipid-rich necrotic cores in hypercholesterolemic mice.

Johansson ME; Zhang X-Y; Edfeldt K; Lundberg AM; Levin MC; Borén J; Li W; Yuan X-M; Folkersen L; Eriksson P; Hedin U; Low H; Sviridov D; Rios FJ; Hansson GK; Yan Z-Q
Article: JOURNAL OF THE ROYAL SOCIETY INTERFACE. 2014;11(97):20140403

Synergy between shear-induced migration and secondary flows on red blood cells transport in arteries: considerations on oxygen transport.

Biasetti J; Spazzini PG; Hedin U; Gasser TC
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2014;307(3):H337-H345

Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury.

Gotha L; Lim SY; Osherov AB; Wolff R; Qiang B; Erlich I; Nili N; Pillarisetti S; Chang Y-T; Tran P-K; Tryggvason K; Hedin U; Tran-Lundmark K; Advani SL; Gilbert RE; Strauss BH
Article: JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY. 2014;25(5):789-796.e7

Early changes of gene expression profiles in the rat model of arterial injury.

Fedorov A; Kostareva A; Raud J; Roy J; Hedin U; Razuvaev A
Article: JOURNAL OF CLINICAL INVESTIGATION. 2014;124(3):1083-1097

Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis.

Kojima Y; Downing K; Kundu R; Miller C; Dewey F; Lancero H; Raaz U; Perisic L; Hedin U; Schadt E; Maegdefessel L; Quertermous T; Leeper NJ
Article: PLOS GENETICS. 2014;10(3):e1004263

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.

Miller CL; Haas U; Diaz R; Leeper NJ; Kundu RK; Patlolla B; Assimes TL; Kaiser FJ; Perisic L; Hedin U; Maegdefessel L; Schunkert H; Erdmann J; Quertermous T; Sczakiel G
Article: PLOS ONE. 2014;9(6):e98904

Contribution of endothelial injury and inflammation in early phase to vein graft failure: the causal factors impact on the development of intimal hyperplasia in murine models.

Tseng C-N; Karlöf E; Chang Y-T; Lengquist M; Rotzius P; Berggren P-O; Hedin U; Eriksson EE
Article: JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS. 2013;27:226-238

Identification of carotid plaque tissue properties using an experimental-numerical approach.

Heiland VM; Forsell C; Roy J; Hedin U; Gasser TC
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(10):2432-2443

Profiling of atherosclerotic lesions by gene and tissue microarrays reveals PCSK6 as a novel protease in unstable carotid atherosclerosis.

Perisic L; Hedin E; Razuvaev A; Lengquist M; Osterholm C; Folkersen L; Gillgren P; Paulsson-Berne G; Ponten F; Odeberg J; Hedin U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2013;33(9):2193-2201

NOD2-mediated innate immune signaling regulates the eicosanoids in atherosclerosis.

Liu H-Q; Zhang X-Y; Edfeldt K; Nijhuis MO; Idborg H; Bäck M; Roy J; Hedin U; Jakobsson P-J; Laman JD; de Kleijn DP; Pasterkamp G; Hansson GK; Yan Z-Q
Article: ATHEROSCLEROSIS. 2013;226(1):67-73

Increased expression of heparanase in symptomatic carotid atherosclerosis.

Osterholm C; Folkersen L; Lengquist M; Pontén F; Renné T; Li J; Hedin U
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2012;5(6):656-665

Identification of the BCAR1-CFDP1-TMEM170A locus as a determinant of carotid intima-media thickness and coronary artery disease risk.

Gertow K; Sennblad B; Strawbridge RJ; Ohrvik J; Zabaneh D; Shah S; Veglia F; Fava C; Kavousi M; McLachlan S; Kivimäki M; Bolton JL; Folkersen L; Gigante B; Leander K; Vikström M; Larsson M; Silveira A; Deanfield J; Voight BF; Fontanillas P; Sabater-Lleal M; Colombo GI; Kumari M; Langenberg C; Wareham NJ; Uitterlinden AG; Gabrielsen A; Hedin U; Franco-Cereceda A; Nyyssönen K; Rauramaa R; Tuomainen T-P; Savonen K; Smit AJ; Giral P; Mannarino E; Robertson CM; Talmud PJ; Hedblad B; Hofman A; Erdmann J; Reilly MP; O'Donnell CJ; Farrall M; Clarke R; Franzosi MG; Seedorf U; Syvänen A-C; Hansson GK; Eriksson P; Samani NJ; Watkins H; Price JF; Hingorani AD; Melander O; Witteman JCM; Baldassarre D; Tremoli E; de Faire U; Humphries SE; Hamsten A
Article: ATHEROSCLEROSIS. 2012;225(2):491-496

High plasma adiponectin concentration is associated with all-cause mortality in patients with carotid atherosclerosis.

Persson J; Folkersen L; Ekstrand J; Helleberg J; Gabrielsen A; Lundman P; Hedin U; Paulsson-Berne G
Article: ATHEROSCLEROSIS. 2012;224(1):266-273

Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis - Potential role in plaque stabilization.

Smedbakken LM; Halvorsen B; Daissormont I; Ranheim T; Michelsen AE; Skjelland M; Sagen EL; Folkersen L; Krohg-Sørensen K; Russell D; Holm S; Ueland T; Fevang B; Hedin U; Yndestad A; Gullestad L; Hansson GK; Biessen EA; Aukrust P
Article: CIRCULATION. 2012;126(8):952-962

Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation.

Salagianni M; Galani IE; Lundberg AM; Davos CH; Varela A; Gavriil A; Lyytikäinen L-P; Lehtimäki T; Sigala F; Folkersen L; Gorgoulis V; Lenglet S; Montecucco F; Mach F; Hedin U; Hansson GK; Monaco C; Andreakos E
Article: AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY. 2012;302(11):L1159-L1166

Antenatal imatinib treatment reduces pulmonary vascular remodeling in a rat model of congenital diaphragmatic hernia.

Chang Y-T; Ringman Uggla A; Osterholm C; Tran P-K; Eklöf A-C; Lengquist M; Hedin U; Tran-Lundmark K; Frenckner B
Article: MOLECULAR MEDICINE. 2012;18(1):669-675

Prediction of ischemic events on the basis of transcriptomic and genomic profiling in patients undergoing carotid endarterectomy.

Folkersen L; Persson J; Ekstrand J; Agardh HE; Hansson GK; Gabrielsen A; Hedin U; Paulsson-Berne G
Article: ATHEROSCLEROSIS. 2012;220(1):102-109

The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation.

Wang J; Razuvaev A; Folkersen L; Hedin E; Roy J; Brismar K; Hedin U
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2011;42(6):722-730

Correlations between clinical variables and gene-expression profiles in carotid plaque instability.

Razuvaev A; Ekstrand J; Folkersen L; Agardh H; Markus D; Swedenborg J; Hansson GK; Gabrielsen A; Paulsson-Berne G; Roy J; Hedin U
Article: CIRCULATION. 2011;124(22):2433-7

Identification of a danger-associated peptide from apolipoprotein B100 (ApoBDS-1) that triggers innate proatherogenic responses.

Ketelhuth DFJ; Rios FJO; Wang Y; Liu H; Johansson ME; Fredrikson GN; Hedin U; Gidlund M; Nilsson J; Hansson GK; Yan Z-Q
Article: ATHEROSCLEROSIS. 2011;215(2):411-416

12- and 15-lipoxygenases in human carotid atherosclerotic lesions: associations with cerebrovascular symptoms.

Gertow K; Nobili E; Folkersen L; Newman JW; Pedersen TL; Ekstrand J; Swedenborg J; Kühn H; Wheelock CE; Hansson GK; Hedin U; Haeggström JZ; Gabrielsen A
Article: JOURNAL OF INTERNAL MEDICINE. 2011;269(2):200-210

Expression of fatty acid-binding protein 4/aP2 is correlated with plaque instability in carotid atherosclerosis.

Agardh HE; Folkersen L; Ekstrand J; Marcus D; Swedenborg J; Hedin U; Gabrielsen A; Paulsson-Berne G
Article: CIRCULATION-GENOMIC AND PRECISION MEDICINE. 2010;3(4):365-373

Association of genetic risk variants with expression of proximal genes identifies novel susceptibility genes for cardiovascular disease.

Folkersen L; van't Hooft F; Chernogubova E; Agardh HE; Hansson GK; Hedin U; Liska J; Syvänen A-C; Paulsson-Berne G; Franco-Cereceda A; Hamsten A; Gabrielsen A; Eriksson P; BiKE and ASAP study groups
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2010;88(8):795-806

Thromboxane synthase expression and thromboxane A2 production in the atherosclerotic lesion.

Gabrielsen A; Qiu H; Bäck M; Hamberg M; Hemdahl A-L; Agardh H; Folkersen L; Swedenborg J; Hedin U; Paulsson-Berne G; Haeggström JZ; Hansson GK
Article: JOURNAL OF VASCULAR SURGERY. 2010;52(1):167-175

Tissue factor pathway inhibitor-2 is induced by fluid shear stress in vascular smooth muscle cells and affects cell proliferation and survival.

Ekstrand J; Razuvaev A; Folkersen L; Roy J; Hedin U
Article: LAKARTIDNINGEN. 2010;107(21):1356-1357

[Ethics Review Boards discriminate the most severely ill--Swedish researchers are prevented to participate in an international study].

Björck M; Berg B; Hedin U; Wingren U
Article: ANNALS OF BIOMEDICAL ENGINEERING. 2010;38(2):380-390

Hemodynamics of the normal aorta compared to fusiform and saccular abdominal aortic aneurysms with emphasis on a potential thrombus formation mechanism.

Biasetti J; Gasser TC; Auer M; Hedin U; Labruto F
Article: JOURNAL OF VASCULAR SURGERY. 2009;50(2):388-395

Mast cells associate with neovessels in the media and adventitia of abdominal aortic aneurysms.

Mäyränpää MI; Trosien JA; Fontaine V; Folkesson M; Kazi M; Eriksson P; Swedenborg J; Hedin U
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2009;87(4):337-346

Genetic variants of TNFSF4 and risk for carotid artery disease and stroke.

Olofsson PS; Söderström LA; Jern C; Sirsjö A; Ria M; Sundler E; de Faire U; Wiklund PG; Ohrvik J; Hedin U; Paulsson-Berne G; Hamsten A; Eriksson P; Hansson GK
Article: JOURNAL OF NUCLEAR MEDICINE. 2008;49(10):1601-1605

High 18F-FDG Uptake in synthetic aortic vascular grafts on PET/CT in symptomatic and asymptomatic patients.

Wassélius J; Malmstedt J; Kalin B; Larsson S; Sundin A; Hedin U; Jacobsson H
Article: ATHEROSCLEROSIS. 2008;199(2):310-316

Noninvasive real-time imaging of intima thickness after rat carotid artery balloon injury using ultrasound biomicroscopy.

Razuvaev A; Lund K; Roy J; Hedin U; Caidahl K
Article: CIRCULATION RESEARCH. 2008;103(1):43-52

Heparan sulfate in perlecan promotes mouse atherosclerosis: roles in lipid permeability, lipid retention, and smooth muscle cell proliferation.

Tran-Lundmark K; Tran P-K; Paulsson-Berne G; Fridén V; Soininen R; Tryggvason K; Wight TN; Kinsella MG; Borén J; Hedin U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):975-982

Variants of the interferon regulatory factor 5 gene regulate expression of IRF5 mRNA in atherosclerotic tissue but are not associated with myocardial infarction.

Mälarstig A; Sigurdsson S; Eriksson P; Paulsson-Berne G; Hedin U; Wallentin L; Siegbahn A; Hamsten A; Syvänen A-C
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2008;28(5):1005-1011

A potential role of the CXC chemokine GROalpha in atherosclerosis and plaque destabilization: downregulatory effects of statins.

Breland UM; Halvorsen B; Hol J; Øie E; Paulsson-Berne G; Yndestad A; Smith C; Otterdal K; Hedin U; Waehre T; Sandberg WJ; Frøland SS; Haraldsen G; Gullestad L; Damås JK; Hansson GK; Aukrust P
Article: CIRCULATION. 2008;117(10):1292-1301

CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice.

Olofsson PS; Söderström LA; Wågsäter D; Sheikine Y; Ocaya P; Lang F; Rabu C; Chen L; Rudling M; Aukrust P; Hedin U; Paulsson-Berne G; Sirsjö A; Hansson GK
Article: THROMBOSIS AND HAEMOSTASIS. 2007;98(2):427-433

Presence of NGAL/MMP-9 complexes in human abdominal aortic aneurysms.

Folkesson M; Kazi M; Zhu C; Silveira A; Hemdahl A-L; Hamsten A; Hedin U; Swedenborg J; Eriksson P
Article: JOURNAL OF VASCULAR SURGERY. 2007;46(1):108-115

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling.

Razuvaev A; Henderson B; Girnita L; Larsson O; Axelson M; Hedin U; Roy J
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2007;292(6):H3158-H3163

Cardioprotective effect of rosuvastatin in vivo is dependent on inhibition of geranylgeranyl pyrophosphate and altered RhoA membrane translocation.

Bulhak A; Roy J; Hedin U; Sjöquist P-O; Pernow J
Article: ATHEROSCLEROSIS. 2007;190(2):264-270

Reduced perlecan expression and accumulation in human carotid atherosclerotic lesions.

Tran P-K; Agardh HE; Tran-Lundmark K; Ekstrand J; Roy J; Henderson B; Gabrielsen A; Hansson GK; Swedenborg J; Paulsson-Berne G; Hedin U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2006;103(21):8161-8166

Expression of 5-lipoxygenase and leukotriene A4 hydrolase in human atherosclerotic lesions correlates with symptoms of plaque instability.

Qiu H; Gabrielsen A; Agardh HE; Wan M; Wetterholm A; Wong C-H; Hedin U; Swedenborg J; Hansson GK; Samuelsson B; Paulsson-Berne G; Haeggström JZ
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2006;26(1):136-142

Expression of neutrophil gelatinase-associated lipocalin in atherosclerosis and myocardial infarction.

Hemdahl A-L; Gabrielsen A; Zhu C; Eriksson P; Hedin U; Kastrup J; Thorén P; Hansson GK
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(7):e113-e116

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents.

Olofsson PS; Jatta K; Wågsäter D; Gredmark S; Hedin U; Paulsson-Berne G; Söderberg-Nauclér C; Hansson GK; Sirsjö A
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(7):1341-1346

Difference in matrix-degrading protease expression and activity between thrombus-free and thrombus-covered wall of abdominal aortic aneurysm.

Kazi M; Zhu C; Roy J; Paulsson-Berne G; Hamsten A; Swedenborg J; Hedin U; Eriksson P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2005;25(4):723-728

Powerful inflammatory properties of large vein endothelium in vivo.

Eriksson EE; Karlof E; Lundmark K; Rotzius P; Hedin U; Xie X
Article: CARDIOVASCULAR RESEARCH. 2005;65(2):535-545

Allogenic immune response promotes the accumulation of host-derived smooth muscle cells in transplant arteriosclerosis.

Religa P; Bojakowski K; Bojakowska M; Gaciong Z; Thyberg J; Hedin U
Article: PROTEIN JOURNAL. 2004;23(4):263-271

Identification of endothelial proteins by MALDI-MS using a compact disc microfluidic system.

Hirschberg D; Tryggvason S; Gustafsson M; Bergman T; Swedenborg J; Hedin U; Jörnvall H
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(4):750-755

CXCL16/SR-PSOX is an interferon-gamma-regulated chemokine and scavenger receptor expressed in atherosclerotic lesions.

Wuttge DM; Zhou X; Sheikine Y; Wågsäter D; Stemme V; Hedin U; Stemme S; Hansson GK; Sirsjö A
Article: CIRCULATION RESEARCH. 2004;94(4):550-558

Increased intimal hyperplasia and smooth muscle cell proliferation in transgenic mice with heparan sulfate-deficient perlecan.

Tran P-K; Tran-Lundmark K; Soininen R; Tryggvason K; Thyberg J; Hedin U
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2003;249(1-2):75-83

Arteriosclerosis in rat aortic allografts: dynamics of cell growth, apoptosis and expression of extracellular matrix proteins.

Religa P; Bojakowski K; Gaciong Z; Thyberg J; Hedin U
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2002;193(3):365-372

Inhibition of rat smooth muscle cell adhesion and proliferation by non-anticoagulant heparins.

Kazi M; Lundmark K; Religa P; Gouda I; Larm O; Ray A; Swedenborg J; Hedin U
Article: TRANSPLANTATION. 2002;74(9):1310-1315

Smooth-muscle progenitor cells of bone marrow origin contribute to the development of neointimal thickenings in rat aortic allografts and injured rat carotid arteries.

Religa P; Bojakowski K; Maksymowicz M; Bojakowska M; Sirsjö A; Gaciong Z; Olszewski W; Hedin U; Thyberg J
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(15):12741-12748

Recombinant human laminin-10 (alpha5beta1gamma1). Production, purification, and migration-promoting activity on vascular endothelial cells.

Doi M; Thyboll J; Kortesmaa J; Jansson K; Iivanainen A; Parvardeh M; Timpl R; Hedin U; Swedenborg J; Tryggvason K
Article: EXPERIMENTAL CELL RESEARCH. 2002;273(2):169-177

Fibronectin promotes cell cycle entry in smooth muscle cells in primary culture.

Roy J; Tran PK; Religa P; Kazi M; Henderson B; Lundmark K; Hedin U
Article: ATHEROSCLEROSIS. 2002;160(1):215-222

Enhanced vasoconstrictor effect of big endothelin-1 in patients with atherosclerosis: relation to conversion to endothelin-1.

Böhm F; Johansson BL; Hedin U; Alving K; Pernow J
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2001;188(1):67-74

Perlecan inhibits smooth muscle cell adhesion to fibronectin: role of heparan sulfate.

Lundmark K; Tran PK; Kinsella MG; Clowes AW; Wight TN; Hedin U
Article: DIFFERENTIATION. 2001;67(1-2):50-58

Phenotypic modulation of arterial smooth muscle cells is associated with prolonged activation of ERK1/2.

Roy J; Kazi M; Hedin U; Thyberg J
Article: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2000;20(5):419-426

Fucoidan inhibits smooth muscle cell proliferation and reduces mitogen-activated protein kinase activity.

Religa P; Kazi M; Thyberg J; Gaciong Z; Swedenborg J; Hedin U
Article: TRANSPLANTATION. 2000;70(1):65-72

Arteriosclerosis in rat aortic allografts: early changes in endothelial integrity and smooth muscle phenotype.

Bojakowski K; Religa P; Bojakowska M; Hedin U; Gaciong Z; Thyberg J
Article: ATHEROSCLEROSIS. 1999;145(1):33-43

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines.

Frostegård J; Ulfgren AK; Nyberg P; Hedin U; Swedenborg J; Andersson U; Hansson GK
Article: CIRCULATION RESEARCH. 1998;83(3):305-313

Heparan sulfate proteoglycans mediate a potent inhibitory signal for migration of vascular smooth muscle cells.

Koyama N; Kinsella MG; Wight TN; Hedin U; Clowes AW
Article: JOURNAL OF VASCULAR SURGERY. 1998;27(3):512-520

Heparin inhibits thrombin-induced mitogen-activated protein kinase signaling in arterial smooth muscle cells.

Hedin U; Daum G; Clowes AW
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(10):2257-2263

Expression of phospholipase A2 isoforms in human normal and atherosclerotic arterial wall.

Elinder LS; Dumitrescu A; Larsson P; Hedin U; Frostegård J; Claesson HE
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(10):1977-1984

Role of tyrosine kinases in extracellular matrix-mediated modulation of arterial smooth muscle cell phenotype.

Hedin U; Thyberg J; Roy J; Dumitrescu A; Tran PK
Article: LABORATORY INVESTIGATION. 1997;77(1):93-101

Expression of caveolae on the surface of rat arterial smooth muscle cells is dependent on the phenotypic state of the cells.

Thyberg J; Roy J; Tran PK; Blomgren K; Dumitrescu A; Hedin U
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 1997;172(1):109-116

Disruption of integrin alpha 5 beta 1 signaling does not impair PDGF-BB-mediated stimulation of the extracellular signal-regulated kinase pathway in smooth muscle cells.

Hedin UL; Daum G; Clowes AW
Article: CIRCULATION RESEARCH. 1997;81(1):17-23

Diverse effects of heparin on mitogen-activated protein kinase-dependent signal transduction in vascular smooth muscle cells.

Daum G; Hedin U; Wang Y; Wang T; Clowes AW
Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 1997;45(6):837-846

Phenotypic modulation of smooth muscle cells after arterial injury is associated with changes in the distribution of laminin and fibronectin.

Thyberg J; Blomgren K; Roy J; Tran PK; Hedin U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1996;16(2):187-193

Autocrine induction of DNA synthesis by mechanical injury of cultured smooth muscle cells. Potential role of FGF and PDGF.

Calara F; Ameli S; Hultgårdh-Nilsson A; Cercek B; Kupfer J; Hedin U; Forrester J; Shah PK; Nilsson J
Article: CELL AND TISSUE RESEARCH. 1995;281(3):421-433

Phenotypic modulation of smooth muscle cells during the formation of neointimal thickenings in the rat carotid artery after balloon injury: an electron-microscopic and stereological study.

Thyberg J; Blomgren K; Hedin U; Dryjski M
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Editorial comment: ATHEROSCLEROSIS. 2023;387:117365

The more the merrier: Severe vascular injury increases engagement of smooth muscle cell clones in intimal repair.

Hedin U; Chemaly M; Matic L
Editorial comment: CARDIOVASCULAR RESEARCH. 2023;119(5):1100-1102

Smooth muscle cell oligoclonality in vascular disease: same origin, different destinies.

Matic L; Chemaly M; Hedin U
Review: EUROPEAN CARDIOLOGY. 2022;17:e09

Circulating Biomarkers in Lower Extremity Artery Disease.

Ziegler L; Hedin U; Gottsäter A
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2021;41(9):2384-2386

Another Notch in the Cap.

Hedin U
Review: AMERICAN JOURNAL OF NEURORADIOLOGY. 2021;42(9):1566-1575

Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement.

Saba L; Brinjikji W; Spence JD; Wintermark M; Castillo M; de Borst GJ; Yang Q; Yuan C; Buckler A; Edjlali M; Saam T; Saloner D; Lal BK; Capodanno D; Sun J; Balu N; Naylor R; Lugt AVD; Wasserman BA; Kooi ME; Wardlaw J; Gillard J; Lanzino G; Hedin U; Mikulis D; Gupta A; DeMarco JK; Hess C; Goethem JV; Hatsukami T; Rothwell P; Brown MM; Moody AR
Corrigendum: SCIENTIFIC REPORTS. 2021;11(1):8852

Author Correction: Expression of CARD8 in human atherosclerosis and its regulation of inflammatory proteins in human endothelial cells.

Paramel GV; Karadimou G; Eremo AG; Ljungberg LU; Hedin U; Olofsson PS; Folkersen L; Paulsson-Berne G; Sirsjö A; Fransén K
Editorial comment: JOURNAL OF INTERNAL MEDICINE. 2020;288(5):489-490

Translation of recent discoveries in cardiovascular disease research to novel therapeutic strategies.

Hedin U
Letter: CARDIOVASCULAR DIAGNOSIS AND THERAPY. 2020;10(5):1352-1355

Can COVID19 trigger the plaque vulnerability-a Kounis syndrome warning for "asymptomatic subjects".

Saba L; Gerosa C; Wintermark M; Hedin U; Fanni D; Suri JS; Balestrieri A; Faa G
Review: JOURNAL OF VASCULAR SURGERY. 2019;69(3):944-951

Recent advances in therapeutic targeting of inflammation in atherosclerosis.

Hedin U; Matic LP
Other: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2017;53(5):615-616

Jesper Swedenborg In Memoriam

Hedin U; Hultgren R
Editorial comment: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 2016;51(5):622

Commentary on 'Plaque Echolucency and the Risk of Ischaemic Stroke in Patients with Asymptomatic Carotid Stenosis Within the First Asymptomatic Carotid Surgery Trial (ACST-1)'.

Roy J; Hedin U
Letter: JOURNAL OF VASCULAR ACCESS. 2016;17(1):e3-e4

VORTEC technique in central venous recanalization for haemodialysis access salvage.

Törnqvist P; Hedin U; Asciutto G; Engström J; Bountouris I; Kristmundsson T; Sterner G; Dias NV
Letter: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2015;179:370-372

Aspirin-triggered 15-epi-lipoxin A₄ signals through FPR2/ALX in vascular smooth muscle cells and protects against intimal hyperplasia after carotid ligation.

Petri MH; Laguna-Fernandez A; Tseng C-N; Hedin U; Perretti M; Bäck M
Corrigendum: PLOS ONE. 2015;10(5):e0126079

Correction: Schip1 Is a Novel Podocyte Foot Process Protein that Mediates Actin Cytoskeleton Rearrangements and Forms a Complex with Nherf2 and Ezrin.

Perisic L; Rodriguez PQ; Hultenby K; Sun Y; Lal M; Betsholtz C; Uhlén M; Wernerson A; Hedin U; Pikkarainen T; Tryggvason K; Patrakka J
Review: LAKARTIDNINGEN. 2013;110(7):354-357

[Tools for control of bleeding during vascular trauma].

Wahlgren CM; Montán C; Hedin U
Review: LAKARTIDNINGEN. 2011;108(8):406-410

[Hemodialysis access--a vascular surgical problem].

Hedin U
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:80S

Regulation of Endothelin-1 and Endothelin Receptors by Shear Stress in Vascular Smooth Muscle Cells

Ekstrand J; Razuvaev A; Roy J; Hedin U
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:79S

A Mouse Model of Vascular Grafting

Tseng C-N; Eriksson E; Hedin U
Meeting abstract: JOURNAL OF VASCULAR SURGERY. 2010;51:72S-73S

A Specific Inhibitor of IGF-1 Receptor - Picropodophyllin Can Suppress Atheroma Progression and Has a Stabilizing Effect on Atherosclerotic Lesions in ApoE Deficient Mice

Razuvaev A; Larsson O; Axelson M; Hedin U; Roy J
Review: MOLECULAR BIOSYSTEMS. 2010;6(2):289-304

The use of network analyses for elucidating mechanisms in cardiovascular disease.

Diez D; Wheelock AM; Goto S; Haeggström JZ; Paulsson-Berne G; Hansson GK; Hedin U; Gabrielsen A; Wheelock CE
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2008;9(1):198

ENHANCED EXPRESSION OF THE CHEMOKINE CXCL1 IN ATHEROSCLEROTIC DISORDERS, DOWN-REGULATORY EFFECTS OF STATIN

Breland UM; Halvorsen B; Hol J; Oie E; Yndestad A; Smith C; Otterdal K; Hedin U; Waehre T; Sandberg W; Froland SS; Haraldsen G; Gullestad L; Hansson GK; Damas JK; Aukrust P
Review: LAKARTIDNINGEN. 2007;104(6):412-414

[Symptomatic carotid stenosis should be treated surgically, not with stenting. Great risks with stents, according to studies].

Swedenborg J; Hedin U; Bergqvist D
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):406

Invariant NKT cells present in human atherosclerotic lesions

Agardh HE; Eriksson P; Tupin E; Kazi M; Hedin U; Olsson A; Hansson GK; Swedenborg J; Paulsson-Berne G
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):248

Inflammatory response inhuman atherosclerosis:bike -: Biobank of karolinska endartherectomy

Paulsson-Berne G; Gabrielsen A; Agardh HE; Ekstrand J; Marcus D; Bodin I; Swedenborg J; Hansson GK; Hedin U
Review: ACTA CHIRURGICA BELGICA. 2004;104(6):606-608

Influence of the intraluminal thrombus in abdominal aortic aneurysms.

Swedenborg J; Kazi M; Eriksson P; Hedin U
Review: CURRENT OPINION IN LIPIDOLOGY. 2004;15(5):559-565

Control of smooth muscle cell proliferation in vascular disease.

Hedin U; Roy J; Tran P-K
Published paper: JOURNAL OF VASCULAR SURGERY. 2003;38(6):1283-1292

Influence of intraluminal thrombus on structural and cellular composition of abdominal aortic aneurysm wall.

Kazi M; Thyberg J; Religa P; Roy J; Eriksson P; Hedin U; Swedenborg J
Published paper: TRANSPLANTATION PROCEEDINGS. 2002;34(2):687-688

Extracellular matrix composition and cellular mechanisms of transplant vasculopathy in rat aortic allografts.

Religa P; Bojakowski K; Bojakowska M; Gaciong Z; Thyberg J; Hedin U
Meeting abstract: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. 2001;33(6):A100

Arteriosclerosis in rat aortic allografts: Dependence of cell phenotype, growth and apoptosis on extracellular matrix composition

Religa P; Bojakowski K; Gaciong Z; Hedin U; Thyberg J
Published paper: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2000;36(5 Suppl 1):S418-S420

Enhanced vasoconstrictor response to endothelin-B-receptor stimulation in patients with atherosclerosis.

Pernow J; Böhm F; Johansson BL; Hedin U; Rydén L
Review: THROMBOSIS AND HAEMOSTASIS. 1999;82 Suppl 1:23-26

Control of smooth muscle cell proliferation--the role of the basement membrane.

Hedin U; Roy J; Tran PK; Lundmark K; Rahman A
Review: LAKARTIDNINGEN. 1999;96(13):1585-1590

[Intermittent claudication--a major cardiovascular risk factor. Proposed guidelines for investigation and treatment].

Svensson P; Wahlberg E; Hedin U; Ostergren J
Review: LAKARTIDNINGEN. 1997;94(26-27):2481-2484

[Restenosis--elusive shadow of vascular biology. New discoveries set hopes about future therapy].

Hedin U
Review: LAKARTIDNINGEN. 1997;94(14):1276-1283

[Gene therapy in peripheral vascular disease. A future therapeutic method?].

Wahlberg E; Hedin U
Review: EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY. 1997;13(2):101-111

Gene therapy and vascular disease: potential applications in vascular surgery.

Hedin U; Wahlberg E
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