Ulf Diczfalusy

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2022;23(23):15168

Pregnancy Increases CYP3A Enzymes Activity as Measured by the 4β-Hydroxycholesterol/Cholesterol Ratio.

Mlugu EM; Minzi OM; Kamuhabwa AAR; Diczfalusy U; Aklillu E
Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2021;9(6):e00884

Studies on CYP3A activity during the menstrual cycle as measured by urinary 6β-hydroxycortisol/cortisol.

Bergström H; Lindahl A; Warnqvist A; Diczfalusy U; Ekström L; Björkhem-Bergman L
Article: CANCERS. 2021;13(18):4689

CYP3A Activity in End-of-Life Cancer Patients Measured by 4β-Hydroxycholesterol/cholesterol Ratio, in Men and Women.

Bergström H; Helde Frankling M; Klasson C; Lövgren Sandblom A; Diczfalusy U; Björkhem-Bergman L
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2021;178(16):3294-3308

Early or deferred initiation of efavirenz during rifampicin-based TB therapy has no significant effect on CYP3A induction in TB-HIV infected patients.

Aklillu E; Zumla A; Habtewold A; Amogne W; Makonnen E; Yimer G; Burhenne J; Diczfalusy U
Article: JOURNAL OF PERSONALIZED MEDICINE. 2021;11(6):457

Evaluation of 1β-Hydroxylation of Deoxycholic Acid as a Non-Invasive Urinary Biomarker of CYP3A Activity in the Assessment of Inhibition-Based Drug-Drug Interaction in Healthy Volunteers.

Li X-Q; Thelingwani RS; Bertilsson L; Diczfalusy U; Andersson TB; Masimirembwa C
Article: JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY. 2019;190:115-125

First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.

Lütjohann D; Björkhem I; Friedrichs S; Kerksiek A; Lövgren-Sandblom A; Geilenkeuser W-J; Ahrends R; Andrade I; Ansorena D; Astiasarán I; Baila-Rueda L; Barriuso B; Becker S; Bretillon L; Browne RW; Caccia C; Ceglarek U; Cenarro A; Crick PJ; Fauler G; Garcia-Llatas G; Gray R; Griffiths WJ; Gylling H; Harding S; Helmschrodt C; Iuliano L; Janssen H-G; Jones P; Kaipiainen L; Kannenberg F; Lagarda MJ; Leoni V; Lottenberg AM; MacKay DS; Matysik S; McDonald J; Menendez-Carreño M; Myrie SB; Sutti Nunes V; Ostlund RE; Polisecki E; Ramos F; Rideout TC; Schaefer EJ; Schmitz G; Wang Y; Zerbinati C; Diczfalusy U; Schött H-F
Article: AAPS JOURNAL. 2019;21(4):58

Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol-an Interaction Study in Healthy Volunteers.

Gjestad C; Hole K; Haslemo T; Diczfalusy U; Molden E
Article: BIOCHIMIE. 2018;153:26-32

International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods.

Lütjohann D; Björkhem I; Friedrichs S; Kerksiek A; Geilenkeuser W-J; Lövgren-Sandblom A; Ansorena D; Astiasarán I; Baila-Rueda L; Barriuso B; Bretillon L; Browne RW; Caccia C; Cenarro A; Crick PJ; Fauler G; García-Llatas G; Griffiths WJ; Iuliano L; Lagarda MJ; Leoni V; Lottenberg AM; Matysik S; McDonald J; Rideout TC; Schmitz G; Nunes VS; Wang Y; Zerbinati C; Diczfalusy U; Schött H-F
Article: BMC PHARMACOLOGY & TOXICOLOGY. 2018;19(1):33

Inflammation down-regulates CYP3A4-catalysed drug metabolism in hemodialysis patients.

Molanaei H; Qureshi AR; Heimbürger O; Lindholm B; Diczfalusy U; Anderstam B; Bertilsson L; Stenvinkel P
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2016;82(6):1539-1549

Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance.

Vanhove T; de Jonge H; de Loor H; Annaert P; Diczfalusy U; Kuypers DRJ
Article: DRUG METABOLISM AND DISPOSITION. 2016;44(9):1480-1489

CYP3A Specifically Catalyzes 1β-Hydroxylation of Deoxycholic Acid: Characterization and Enzymatic Synthesis of a Potential Novel Urinary Biomarker for CYP3A Activity.

Hayes MA; Li X-Q; Grönberg G; Diczfalusy U; Andersson TB
Article: MEDICINE. 2016;95(34):e4631

Prevalence and risk factors for efavirenz-based antiretroviral treatment-associated severe vitamin D deficiency: A prospective cohort study.

Nylén H; Habtewold A; Makonnen E; Yimer G; Bertilsson L; Burhenne J; Diczfalusy U; Aklillu E
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2016;118(6):499-502

Effect of Statin Treatment on Plasma 4β-Hydroxycholesterol Concentrations.

Björkhem-Bergman L; Nylén H; Eriksson M; Parini P; Diczfalusy U
Article: PHARMACOLOGY RESEARCH & PERSPECTIVES. 2015;3(6):e00192

miRNA-27b levels are associated with CYP3A activity in vitro and in vivo.

Ekström L; Skilving I; Ovesjö M-L; Aklillu E; Nylén H; Rane A; Diczfalusy U; Björkhem-Bergman L
Article: PLOS ONE. 2015;10(4):e0121984

No impact of vitamin D on the CYP3A biomarker 4β-hydroxycholesterol in patients with abnormal glucose regulation.

Mannheimer B; Wagner H; Östenson C-G; Diczfalusy U
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2014;69(12):3311-3319

Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment.

Ngaimisi E; Minzi O; Mugusi S; Sasi P; Riedel K-D; Suda A; Ueda N; Bakari M; Janabi M; Mugusi F; Bertilsson L; Burhenne J; Aklillu E; Diczfalusy U
Article: MICROCIRCULATION. 2014;21(7):587-592

Immediate effect of passive smoking on microcirculatory flow.

Henriksson P; Lu Q; Diczfalusy U; Freyschuss A
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2014;115(4):366-371

Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives.

Nylén H; Björkhem-Bergman L; Ekström L; Roh H-K; Bertilsson L; Eliasson E; Lindh JD; Diczfalusy U
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2014;69(7):1933-1937

Reduction of nevirapine-driven HIV mutations by carbamazepine is modulated by CYP3A activity.

Baranyai D; Muro E; Gödtel-Armbrust U; Schirmer MA; Kisanga E; Diczfalusy U; Fillekes Q; Schuurman R; Burger D; Wojnowski L
Article: JOURNAL OF LIPID RESEARCH. 2014;55(6):1165-1172

On the formation of 7-ketocholesterol from 7-dehydrocholesterol in patients with CTX and SLO.

Björkhem I; Diczfalusy U; Lövgren-Sandblom A; Starck L; Jonsson M; Tallman K; Schirmer H; Ousager LB; Crick PJ; Wang Y; Griffiths WJ; Guengerich FP
Article: DRUG METABOLISM AND PHARMACOKINETICS. 2014;29(4):352-355

Quinine compared to 4β-hydroxycholesterol and midazolam as markers for CYP3A induction by rifampicin.

Björkhem-Bergman L; Bäckström T; Nylén H; Rönquist-Nii Y; Bredberg E; Andersson TB; Bertilsson L; Diczfalusy U
Article: PHARMACOGENOMICS JOURNAL. 2013;13(6):484-489

Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients.

Habtewold A; Amogne W; Makonnen E; Yimer G; Nylén H; Riedel K-D; Aderaye G; Bertilsson L; Burhenne J; Diczfalusy U; Aklillu E
Article: DRUG METABOLISM AND DISPOSITION. 2013;41(8):1488-1493

Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin.

Björkhem-Bergman L; Bäckström T; Nylén H; Rönquist-Nii Y; Bredberg E; Andersson TB; Bertilsson L; Diczfalusy U
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2013;75(6):1536-1540

A comparison of 4β-hydroxycholesterol : cholesterol and 6β-hydroxycortisol : cortisol as markers of CYP3A4 induction.

Mårde Arrhén Y; Nylén H; Lövgren-Sandblom A; Kanebratt KP; Wide K; Diczfalusy U
Article: DRUG METABOLISM AND DISPOSITION. 2013;41(4):704-708

Serum levels of 25-hydroxyvitamin D and the CYP3A biomarker 4β-hydroxycholesterol in a high-dose vitamin D supplementation study.

Björkhem-Bergman L; Nylén H; Norlin A-C; Lindh JD; Ekström L; Eliasson E; Bergman P; Diczfalusy U
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2012;68(5):571-577

Metabolism of alprazolam (a marker of CYP3A4) in hemodialysis patients with persistent inflammation.

Molanaei H; Stenvinkel P; Qureshi AR; Carrero JJ; Heimbürger O; Lindholm B; Diczfalusy U; Odar-Cederlöf I; Bertilsson L
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(9):6307-6317

Amidoxime reductase system containing cytochrome b5 type B (CYB5B) and MOSC2 is of importance for lipid synthesis in adipocyte mitochondria.

Neve EPA; Nordling A; Andersson TB; Hellman U; Diczfalusy U; Johansson I; Ingelman-Sundberg M
Article: MICROCIRCULATION. 2012;19(1):86-93

Microvascular reactivity in response to smoking and oral antioxidants in humans.

Henriksson P; Diczfalusy U; Freyschuss A
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2011;67(7):715-722

Cytochrome P450 3A activity in mothers and their neonates as determined by plasma 4β-hydroxycholesterol.

Nylén H; Sergel S; Forsberg L; Lindemalm S; Bertilsson L; Wide K; Diczfalusy U
Article: PHARMACOGENOMICS JOURNAL. 2011;11(2):130-137

Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians.

Gebeyehu E; Engidawork E; Bijnsdorp A; Aminy A; Diczfalusy U; Aklillu E
Article: JOURNAL OF LIPID RESEARCH. 2011;52(1):170-174

High levels of 15-oxygenated steroids in circulation of patients with multiple sclerosis: fact or fiction?

Björkhem I; Lövgren-Sandblom A; Piehl F; Khademi M; Pettersson H; Leoni V; Olsson T; Diczfalusy U
Article: CIRCULATION RESEARCH. 2010;106(4):720-729

FTY720 stimulates 27-hydroxycholesterol production and confers atheroprotective effects in human primary macrophages.

Blom T; Bäck N; Mutka A-L; Bittman R; Li Z; de Lera A; Kovanen PT; Diczfalusy U; Ikonen E
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2009;47(12):709-715

4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man.

Lütjohann D; Marinova M; Schneider B; Oldenburg J; von Bergmann K; Bieber T; Björkhem I; Diczfalusy U
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2009;50(12):5712-5717

Primary open-angle glaucoma: association with cholesterol 24S-hydroxylase (CYP46A1) gene polymorphism and plasma 24-hydroxycholesterol levels.

Fourgeux C; Martine L; Björkhem I; Diczfalusy U; Joffre C; Acar N; Creuzot-Garcher C; Bron A; Bretillon L
Article: JOURNAL OF LIPID RESEARCH. 2009;50(11):2258-2264

Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.

Diczfalusy U; Olofsson KE; Carlsson A-M; Gong M; Golenbock DT; Rooyackers O; Fläring U; Björkbacka H
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2009;105(5):339-344

Human exposure to triclosan via toothpaste does not change CYP3A4 activity or plasma concentrations of thyroid hormones.

Allmyr M; Panagiotidis G; Sparve E; Diczfalusy U; Sandborgh-Englund G
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2009;67(1):38-43

4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin.

Diczfalusy U; Kanebratt KP; Bredberg E; Andersson TB; Böttiger Y; Bertilsson L
Article: CLINICAL PHARMACOLOGY & THERAPEUTICS. 2008;84(5):589-594

Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol.

Kanebratt KP; Diczfalusy U; Bäckström T; Sparve E; Bredberg E; Böttiger Y; Andersson TB; Bertilsson L
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(8):775-781

CYP3A induction and inhibition by different antiretroviral regimens reflected by changes in plasma 4beta-hydroxycholesterol levels.

Josephson F; Bertilsson L; Böttiger Y; Flamholc L; Gisslén M; Ormaasen V; Sönnerborg A; Diczfalusy U
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2008;65(5):708-715

Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy.

Wide K; Larsson H; Bertilsson L; Diczfalusy U
Article: PHARMACOGENETICS AND GENOMICS. 2008;18(3):201-208

4Beta-hydroxycholesterol is a new endogenous CYP3A marker: relationship to CYP3A5 genotype, quinine 3-hydroxylation and sex in Koreans, Swedes and Tanzanians.

Diczfalusy U; Miura J; Roh H-K; Mirghani RA; Sayi J; Larsson H; Bodin KG; Allqvist A; Jande M; Kim J-W; Aklillu E; Gustafsson LL; Bertilsson L
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2007;27(10):2191-2197

Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.

Heverin M; Meaney S; Brafman A; Shafir M; Olin M; Shafaati M; von Bahr S; Larsson L; Lövgren-Sandblom A; Diczfalusy U; Parini P; Feinstein E; Björkhem I
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2007;43(5):695-701

In vivo interconversion of 7beta-hydroxycholesterol and 7-ketocholesterol, potential surrogate markers for oxidative stress.

Larsson H; Böttiger Y; Iuliano L; Diczfalusy U
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2007;856(1-2):15-19

Novel LC-MS/MS method for assay of 7alpha-hydroxy-4-cholesten-3-one in human plasma. Evidence for a significant extrahepatic metabolism.

Lövgren-Sandblom A; Heverin M; Larsson H; Lundström E; Wahren J; Diczfalusy U; Björkhem I
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2007;45(7):377-384

Effects of high-dose itraconazole treatment on lipoproteins in men.

Schneider B; Gerdsen R; Plat J; Dullens S; Björkhem I; Diczfalusy U; Neuvonen PJ; Bieber T; von Bergmann K; Lütjohann D
Article: CURRENT EYE RESEARCH. 2007;32(4):361-366

Cholesterol-24S-hydroxylase (CYP46A1) is specifically expressed in neurons of the neural retina.

Bretillon L; Diczfalusy U; Björkhem I; Maire MA; Martine L; Joffre C; Acar N; Bron A; Creuzot-Garcher C
Article: JOURNAL OF LIPID RESEARCH. 2007;48(4):944-951

Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.

Meaney S; Heverin M; Panzenboeck U; Ekström L; Axelsson M; Andersson U; Diczfalusy U; Pikuleva I; Wahren J; Sattler W; Björkhem I
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2007;42(5):698-705

Increased plasma levels of oxysterols, in vivo markers of oxidative stress, in patients with familial combined hyperlipidemia: reduction during atorvastatin and fenofibrate therapy.

Arca M; Natoli S; Micheletta F; Riggi S; Di Angelantonio E; Montali A; Antonini TM; Antonini R; Diczfalusy U; Iuliano L
Article: PHARMACOGENETICS AND GENOMICS. 2006;16(8):565-568

Effect of SLCO1B1 polymorphism on induction of CYP3A4 by rifampicin.

Niemi M; Kivistö KT; Diczfalusy U; Bodin K; Bertilsson L; Fromm MF; Eichelbaum M
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(7):3810-3820

Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes.

Ohyama Y; Meaney S; Heverin M; Ekström L; Brafman A; Shafir M; Andersson U; Olin M; Eggertsen G; Diczfalusy U; Feinstein E; Björkhem I
Article: LIVER TRANSPLANTATION. 2005;11(12):1494-1504

High preoperative recipient plasma 7beta-hydroxycholesterol is associated with initial poor graft function after liver transplantation.

Corradini SG; Micheletta F; Natoli S; Iappelli M; Di Angelantonio E; De Marco R; Elisei W; Siciliano M; Rossi M; Berloco P; Attili AF; Diczfalusy U; Iuliano L
Article: GASTROENTEROLOGY. 2005;129(2):476-485

Complementary stimulation of hepatobiliary transport and detoxification systems by rifampicin and ursodeoxycholic acid in humans.

Marschall H-U; Wagner M; Zollner G; Fickert P; Diczfalusy U; Gumhold J; Silbert D; Fuchsbichler A; Benthin L; Grundström R; Gustafsson U; Sahlin S; Einarsson C; Trauner M
Article: CLINICAL SCIENCE. 2005;108(6):507-513

Effect of ascorbic acid on microcirculation in patients with Type II diabetes: a randomized placebo-controlled cross-over study.

Lu Q; Björkhem I; Wretlind B; Diczfalusy U; Henriksson P; Freyschuss A
Article: JOURNAL OF LIPID RESEARCH. 2005;46(5):1047-1052

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

Heverin M; Meaney S; Lütjohann D; Diczfalusy U; Wahren J; Björkhem I
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2005;1687(1-3):84-93

Novel pathways of bile acid metabolism involving CYP3A4.

Bodin K; Lindbom U; Diczfalusy U
Article: SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. 2005;65(5):365-375

Patients with atherosclerosis may have increased circulating levels of 27-hydroxycholesterol and cholestenoic acid.

Babiker A; Dzeletovic S; Wiklund B; Pettersson N; Salonen J; Nyyssönen K; Eriksson M; Diczfalusy U; Björkhem I
Article: MOLECULAR AND CELLULAR BIOLOGY. 2004;24(18):8154-8166

Transcriptional regulation of human CYP27 integrates retinoid, peroxisome proliferator-activated receptor, and liver X receptor signaling in macrophages.

Szanto A; Benko S; Szatmari I; Balint BL; Furtos I; Rühl R; Molnar S; Csiba L; Garuti R; Calandra S; Larsson H; Diczfalusy U; Nagy L
Article: NEPHROLOGY DIALYSIS TRANSPLANTATION. 2004;19(4):972-976

Phospholipid plasmalogen, a surrogate marker of oxidative stress, is associated with increased cardiovascular mortality in patients on renal replacement therapy.

Stenvinkel P; Diczfalusy U; Lindholm B; Heimbürger O
Article: JOURNAL OF AOAC INTERNATIONAL. 2004;87(2):467-473

Analysis of cholesterol oxidation products in biological samples.

Diczfalusy U
Article: CLINICAL CHEMISTRY AND LABORATORY MEDICINE. 2004;42(2):186-191

Diagnostic use of cerebral and extracerebral oxysterols.

Leoni V; Masterman T; Mousavi FS; Wretlind B; Wahlund L-O; Diczfalusy U; Hillert J; Björkhem I
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(1):136-140

Vitamin E supplementation in patients with carotid atherosclerosis: reversal of altered oxidative stress status in plasma but not in plaque.

Micheletta F; Natoli S; Misuraca M; Sbarigia E; Diczfalusy U; Iuliano L
Article: JOURNAL OF LIPID RESEARCH. 2004;45(1):186-193

Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease.

Heverin M; Bogdanovic N; Lütjohann D; Bayer T; Pikuleva I; Bretillon L; Diczfalusy U; Winblad B; Björkhem I
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2003;35(8):922-928

Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man.

Tuomainen T-P; Diczfalusy U; Kaikkonen J; Nyyssönen K; Salonen JT
Article: STEROIDS. 2003;68(7-8):595-601

On the origin of the cholestenoic acids in human circulation.

Meaney S; Babiker A; Lütjohann D; Diczfalusy U; Axelson M; Björkhem I
Article: JOURNAL OF LIPID RESEARCH. 2003;44(4):793-799

Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers.

Leoni V; Masterman T; Patel P; Meaney S; Diczfalusy U; Björkhem I
Article: ANALYTICAL BIOCHEMISTRY. 2003;312(2):217-223

Measurement of oxysterols and alpha-tocopherol in plasma and tissue samples as indices of oxidant stress status.

Iuliano L; Micheletta F; Natoli S; Ginanni Corradini S; Iappelli M; Elisei W; Giovannelli L; Violi F; Diczfalusy U
Article: JOURNAL OF LIPID RESEARCH. 2002;43(12):2130-2135

On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.

Meaney S; Bodin K; Diczfalusy U; Björkhem I
Article: NEUROSCIENCE LETTERS. 2002;331(3):163-166

Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis.

Leoni V; Masterman T; Diczfalusy U; De Luca G; Hillert J; Björkhem I
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2002;277(35):31534-31540

Metabolism of 4 beta -hydroxycholesterol in humans.

Bodin K; Andersson U; Rystedt E; Ellis E; Norlin M; Pikuleva I; Eggertsen G; Björkhem I; Diczfalusy U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2002;22(7):1129-1135

Mechanism of accumulation of cholesterol and cholestanol in tendons and the role of sterol 27-hydroxylase (CYP27A1).

von Bahr S; Movin T; Papadogiannakis N; Pikuleva I; Rönnow P; Diczfalusy U; Björkhem I
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2002;22(5):734-742

Oxysterols: friends, foes, or just fellow passengers?

Björkhem I; Diczfalusy U
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2001;1534(2-3):129-138

On the anti-atherogenic effect of the antioxidant BHT in cholesterol-fed rabbits: inverse relation between serum triglycerides and atheromatous lesions.

Freyschuss A; Al-Schurbaji A; Björkhem I; Babiker A; Diczfalusy U; Berglund L; Henriksson P
Article: NEUROSCIENCE LETTERS. 2001;314(1-2):45-48

On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells.

Bogdanovic N; Bretillon L; Lund EG; Diczfalusy U; Lannfelt L; Winblad B; Russell DW; Björkhem I
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(42):38685-38689

Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.

Bodin K; Bretillon L; Aden Y; Bertilsson L; Broomé U; Einarsson C; Diczfalusy U
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2001;276(40):37004-37010

From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans.

Bjorkhem I; Andersson U; Ellis E; Alvelius G; Ellegard L; Diczfalusy U; Sjovall J; Einarsson C
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2001;21(10):E34-E37

Bioavailability of vitamin E as function of food intake in healthy subjects: effects on plasma peroxide-scavenging activity and cholesterol-oxidation products.

Iuliano L; Micheletta F; Maranghi M; Frati G; Diczfalusy U; Violi F
Article: JOURNAL OF LIPID RESEARCH. 2001;42(3):366-371

Oxysterols in the circulation of patients with the Smith-Lemli-Opitz syndrome: abnormal levels of 24S- and 27-hydroxycholesterol.

Björkhem I; Starck L; Andersson U; Lütjohann D; von Bahr S; Pikuleva I; Babiker A; Diczfalusy U
Article: JOURNAL OF CLINICAL INVESTIGATION. 2001;107(5):565-573

Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice.

Alberti S; Schuster G; Parini P; Feltkamp D; Diczfalusy U; Rudling M; Angelin B; Björkhem I; Pettersson S; Gustafsson JA
Article: JOURNAL OF LIPID RESEARCH. 2001;42(1):70-78

Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study.

Meaney S; Hassan M; Sakinis A; Lütjohann D; von Bergmann K; Wennmalm A; Diczfalusy U; Björkhem I
Article: NEUROSCIENCE LETTERS. 2000;293(2):87-90

Plasma levels of 24S-hydroxycholesterol in patients with neurological diseases.

Bretillon L; Sidén A; Wahlund LO; Lütjohann D; Minthon L; Crisby M; Hillert J; Groth CG; Diczfalusy U; Björkhem I
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2000;20(9):2087-2093

Long-term effects of vitamin E, vitamin C, and combined supplementation on urinary 7-hydro-8-oxo-2'-deoxyguanosine, serum cholesterol oxidation products, and oxidation resistance of lipids in nondepleted men.

Porkkala-Sarataho E; Salonen JT; Nyyssönen K; Kaikkonen J; Salonen R; Ristonmaa U; Diczfalusy U; Brigelius-Flohe R; Loft S; Poulsen HE
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2000;1486(2-3):293-298

Formation of oxysterols from different pools of cholesterol as studied by stable isotope technique: cerebral origin of most circulating 24S-hydroxycholesterol in rats, but not in mice.

Meaney S; Lütjohann D; Diczfalusy U; Björkhem I
Article: JOURNAL OF LIPID RESEARCH. 2000;41(5):840-845

Plasma levels of 24S-hydroxycholesterol reflect the balance between cerebral production and hepatic metabolism and are inversely related to body surface.

Bretillon L; Lütjohann D; Ståhle L; Widhe T; Bindl L; Eggertsen G; Diczfalusy U; Björkhem I
Article: JOURNAL OF LIPID RESEARCH. 2000;41(5):814-823

Involvement of the peroxisome proliferator-activated receptor alpha in regulating long-chain acyl-CoA thioesterases.

Hunt MC; Lindquist PJ; Peters JM; Gonzalez FJ; Diczfalusy U; Alexson SE
Article: JOURNAL OF LIPID RESEARCH. 1999;40(8):1417-1425

Elimination of cholesterol as cholestenoic acid in human lung by sterol 27-hydroxylase: evidence that most of this steroid in the circulation is of pulmonary origin.

Babiker A; Andersson O; Lindblom D; van der Linden J; Wiklund B; Lütjohann D; Diczfalusy U; Björkhem I
Article: KIDNEY INTERNATIONAL. 1999;55(5):1899-1911

Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure.

Stenvinkel P; Heimbürger O; Paultre F; Diczfalusy U; Wang T; Berglund L; Jogestrand T
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1999;19(4):967-971

Increased plasma 7 beta-hydroxycholesterol concentrations in a population with a high risk for cardiovascular disease.

Ziedén B; Kaminskas A; Kristenson M; Kucinskienê Z; Vessby B; Olsson AG; Diczfalusy U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(11):1679-1685

Unsaturated fatty acids increase plasminogen activator inhibitor-1 expression in endothelial cells.

Nilsson L; Banfi C; Diczfalusy U; Tremoli E; Hamsten A; Eriksson P
Article: JOURNAL OF LIPID RESEARCH. 1998;39(8):1594-1600

Cholesterol homeostasis in human brain: turnover of 24S-hydroxycholesterol and evidence for a cerebral origin of most of this oxysterol in the circulation.

Björkhem I; Lütjohann D; Diczfalusy U; Ståhle L; Ahlborg G; Wahren J
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1998;1392(2-3):333-339

Transport of side-chain oxidized oxysterols in the human circulation.

Babiker A; Diczfalusy U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(6):884-893

An animal model to study local oxidation of LDL and its biological effects in the arterial wall.

Calara F; Dimayuga P; Niemann A; Thyberg J; Diczfalusy U; Witztum JL; Palinski W; Shah PK; Cercek B; Nilsson J; Regnström J
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1998;18(4):554-561

Sterol 27-hydroxylase- and apoAI/phospholipid-mediated efflux of cholesterol from cholesterol-laden macrophages: evidence for an inverse relation between the two mechanisms.

Westman J; Kallin B; Björkhem I; Nilsson J; Diczfalusy U
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1997;272(42):26253-26261

Elimination of cholesterol in macrophages and endothelial cells by the sterol 27-hydroxylase mechanism. Comparison with high density lipoprotein-mediated reverse cholesterol transport.

Babiker A; Andersson O; Lund E; Xiu RJ; Deeb S; Reshef A; Leitersdorf E; Diczfalusy U; Björkhem I
Article: JOURNAL OF LIPID RESEARCH. 1997;38(10):2049-2061

Ca2+ channel blockers verapamil and nifedipine inhibit apoptosis induced by 25-hydroxycholesterol in human aortic smooth muscle cells.

Ares MP; Pörn-Ares MI; Thyberg J; Juntti-Berggren L; Berggren PO; Diczfalusy U; Kallin B; Björkhem I; Orrenius S; Nilsson J
Article: ATHEROSCLEROSIS. 1997;133(2):183-192

Effect of the oxidation state of LDL on the modulation of arterial vasomotor response in vitro.

Mougenot N; Lesnik P; Ramirez-Gil JF; Nataf P; Diczfalusy U; Chapman MJ; Lechat P
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1997;17(6):1178-1184

Vitamin C reduces cholesterol-induced microcirculatory changes in rabbits.

Freyschuss A; Xiu RJ; Zhang J; Ying X; Diczfalusy U; Jogestrand T; Henriksson P; Björkhem I
Article: JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION. 1997;24(3):264-270

Vitamin A concentration in the liver decreases with age in patients with cystic fibrosis.

Lindblad A; Diczfalusy U; Hultcrantz R; Thorell A; Strandvik B
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1997;1344(3):278-285

Localization of sterol 27-hydroxylase immuno-reactivity in human atherosclerotic plaques.

Crisby M; Nilsson J; Kostulas V; Björkhem I; Diczfalusy U
Article: CIRCULATION. 1997;95(4):840-845

Lipoprotein oxidation and progression of carotid atherosclerosis.

Salonen JT; Nyyssönen K; Salonen R; Porkkala-Sarataho E; Tuomainen TP; Diczfalusy U; Björkhem I
Article: JOURNAL OF LIPID RESEARCH. 1996;37(11):2361-2371

Formation of oxysterols during oxidation of low density lipoprotein by peroxynitrite, myoglobin, and copper.

Patel RP; Diczfalusy U; Dzeletovic S; Wilson MT; Darley-Usmar VM
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1996;93(18):9799-9804

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation.

Lütjohann D; Breuer O; Ahlborg G; Nennesmo I; Sidén A; Diczfalusy U; Björkhem I
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1996;1302(2):145-152

The oxysterols cholest-5-ene-3 beta,4 alpha-diol, cholest-5-ene-3 beta,4 beta-diol and cholestane-3 beta,5 alpha,6 alpha-triol are formed during in vitro oxidation of low density lipoprotein, and are present in human atherosclerotic plaques.

Breuer O; Dzeletovic S; Lund E; Diczfalusy U
Article: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 1996;16(2):208-212

Importance of a novel oxidative mechanism for elimination of intracellular cholesterol in humans.

Lund E; Andersson O; Zhang J; Babiker A; Ahlborg G; Diczfalusy U; Einarsson K; Sjövall J; Björkhem I
Article: JOURNAL OF CLINICAL INVESTIGATION. 1996;97(2):461-468

Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.

Hultén LM; Lindmark H; Diczfalusy U; Björkhem I; Ottosson M; Liu Y; Bondjers G; Wiklund O
Journal article: SCANDINAVIAN JOURNAL OF CLINICAL AND LABORATORY INVESTIGATION, SUPPLEMENT. 1996;56:9-17

Novel pathways for elimination of cholesterol by extrahepatic formation of side-chain oxidized oxysterols

Diczfalusy U; Lund E; Lotjohann D; Bjorkhem I
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1995;1259(3):313-316

Clofibrate treatment increases stearoyl-CoA desaturase mRNA level and enzyme activity in mouse liver.

Diczfalusy U; Eggertsen G; Alexson SE
Article: CHEMISTRY AND PHYSICS OF LIPIDS. 1995;78(2):119-128

Time course of oxysterol formation during in vitro oxidation of low density lipoprotein.

Dzeletovic S; Babiker A; Lund E; Diczfalusy U
Article: ANALYTICAL BIOCHEMISTRY. 1995;225(1):73-80

Determination of cholesterol oxidation products in human plasma by isotope dilution-mass spectrometry.

Dzeletovic S; Breuer O; Lund E; Diczfalusy U
Journal article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1994;91(18):8592-8596

Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.

Björkhem I; Andersson O; Diczfalusy U; Sevastik B; Xiu RJ; Duan C; Lund E
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1994;269(25):17118-17124

Molecular cloning and identification of a rat serum carboxylesterase expressed in the liver.

Alexson SE; Finlay TH; Hellman U; Svensson LT; Diczfalusy U; Eggertsen G
Journal article: CLINICAL NEPHROLOGY. 1994;41(4):183-190

Treatment of IgA nephropathy with omega-3-polyunsaturated fatty acids: a prospective, double-blind, randomized study.

Pettersson EE; Rekola S; Berglund L; Sundqvist KG; Angelin B; Diczfalusy U; Björkhem I; Bergström J
Journal article: PROGRESS IN LIPID RESEARCH. 1994;33(4):403-428

Beta-oxidation of eicosanoids.

Diczfalusy U
Journal article: JOURNAL OF LIPID RESEARCH. 1993;34(7):1107-1113

Peroxisomal chain-shortening of thromboxane B2: evidence for impaired degradation of thromboxane B2 in Zellweger syndrome.

Diczfalusy U; Vesterqvist O; Kase BF; Lund E; Alexson SE
Journal article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1992;267(18):12462-12467

On the mechanism of oxidation of cholesterol at C-7 in a lipoxygenase system.

Lund E; Diczfalusy U; Björkhem I
Journal article: PROGRESS IN CLINICAL AND BIOLOGICAL RESEARCH. 1992;375:253-261

Role of peroxisomes in the degradation of prostaglandins.

Diczfalusy UG; Alexson SE
Journal article: JOURNAL OF CLINICAL INVESTIGATION. 1991;88(3):978-984

Metabolism of prostaglandin F2 alpha in Zellweger syndrome. Peroxisomal beta-oxidation is a major importance for in vivo degradation of prostaglandins in humans.

Diczfalusy U; Kase BF; Alexson SE; Björkhem I
Journal article: DIABETOLOGIA. 1991;34(2):114-118

Impaired intrarenal dopamine production following intravenous sodium chloride infusion in type 1 (insulin-dependent) diabetes mellitus.

Stenvinkel P; Saggar-Malik AK; Wahrenberg H; Diczfalusy U; Bolinder J; Alvestrand A
Journal article: ARTERIOSCLEROSIS AND THROMBOSIS. 1991;11(1):15-22

The antioxidant butylated hydroxytoluene protects against atherosclerosis.

Björkhem I; Henriksson-Freyschuss A; Breuer O; Diczfalusy U; Berglund L; Henriksson P
Journal article: SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION. 1990;50(6):693-696

Stanozolol and experimental atherosclerosis: atherosclerotic development and blood lipids during anabolic steroid therapy of New Zealand white rabbits.

Fogelberg M; Björkhem I; Diczfalusy U; Henriksson P
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1990;1043(2):182-188

Identification of intermediates in the peroxisomal beta-oxidation of linoleic acid.

Diczfalusy U; Alexson SE; Sisfontes L; Olund J; Björkhem I
Journal article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1990;20(1):105-110

Experimental atherosclerosis: effects of oestrogen and atherosclerosis on thromboxane and prostacyclin formation.

Fogelberg M; Vesterqvist O; Diczfalusy U; Henriksson P
Journal article: JOURNAL OF LIPID RESEARCH. 1990;31(2):307-314

Identification of metabolites from peroxisomal beta-oxidation of prostaglandins.

Diczfalusy U; Alexson SE
Journal article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1989;19(4):395-403

Oestrogen-induced changes in lipoprotein metabolism: role in prevention of atherosclerosis in the cholesterol-fed rabbit.

Henriksson P; Stamberger M; Eriksson M; Rudling M; Diczfalusy U; Berglund L; Angelin B
Journal article: JOURNAL OF LIPID RESEARCH. 1988;29(12):1629-1636

Peroxisomal chain-shortening of prostaglandin F2 alpha.

Diczfalusy U; Alexson SE
Journal article: ACTA OPHTHALMOLOGICA. 1988;66(3):341-348

Attempts to define the minimal serum level of vitamin A required for normal visual function in a patient with severe fat malabsorption.

Wachtmeister L; Björkhem I; Diczfalusy U; Emami A
Journal article: PROSTAGLANDINS LEUKOTRIENES AND MEDICINE. 1987;29(1):71-77

Increased aortic thromboxane production in experimental atherosclerosis.

Henriksson P; Stamberger M; Diczfalusy U
Journal article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1987;144(3):1206-1213

Chain-shortening of prostaglandin F2 alpha by rat liver peroxisomes.

Diczfalusy U; Alexson SE; Pedersen JI
Journal article: ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS. 1987;254(1):124-135

Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: development of a novel enzyme assay.

Hecker M; Haurand M; Ullrich V; Diczfalusy U; Hammarström S
Journal article: BIOMEDICAL CHROMATOGRAPHY. 1987;2(5):226-227

Determination of 4-methylpyrazole in plasma using solid phase extraction and HPLC.

Diczfalusy U; Eklöf R
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1986;878(3):387-393

Identification of the major urinary metabolite of prostaglandin E3 in the rat.

Diczfalusy U; Hamberg M
Journal article: LIPIDS. 1985;20(5):283-295

Influence of dietary partially hydrogenated vegetable and marine oils on membrane composition and function of liver microsomes and platelets in the rat.

Blomstrand R; Diczfalusy U; Sisfontes L; Svensson L
Journal article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 1985;834(2):272-274

Formation of 15-HETE as a major hydroxyeicosatetraenoic acid in the atherosclerotic vessel wall.

Henriksson P; Hamberg M; Diczfalusy U
Journal article: CLINICA CHIMICA ACTA. 1983;135(2):189-201

Validation of radioimmunoassay for estradiol-17 beta by isotope dilution-mass spectrometry and by a test of radiochemical purity.

Xing S; Cekan SZ; Diczfalusy U; Falk O; Gustafsson SA; Akerlöf E; Björkhem I
Journal article: ADVANCES IN PROSTAGLANDIN, THROMBOXANE, AND LEUKOTRIENE RESEARCH. 1982;10:15-58

Thromboxane a2: biosynthesis and effects on platelets.

Granström E; Diczfalusy U; Hamberg M; Hansson G; Malmsten C; Samuelsson B
Journal article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 1980;94(4):1417-1423

Enzymatic conversion of C21 endoperoxides to thromboxanes and hydroxy acids.

Diczfalusy U; Hammarström S
Journal article: ADVANCES IN PROSTAGLANDIN AND THROMBOXANE RESEARCH. 1980;6:267-274

Biosynthesis of thromboxanes.

Hammarström S; Diczfalusy U
Journal article: FEBS LETTERS. 1979;105(2):291-295

A structural requirement for the conversion of prostaglandin endoperoxides to thromboxanes.

Diczfalusy U; Hammarström S
Journal article: FEBS LETTERS. 1977;84(2):271-274

Conversion of prostaglandin endoperoxides to C17-hydroxy acids catalyzed by human platelet thromboxane synthase.

Diczfalusy U; Falardeau P; Hammarström S
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Book chapter: 2020;p. 41-79

Side-Chain Oxidized Oxysterols in Health and Disease

Björkhem I; Diczfalusy U
Editorial comment: BIOANALYSIS. 2017;9(9):675-681

Feedback from the EBF - Focus Workshop: bringing assay validation and analysis of biomarkers into practice.

Timmerman P; Scheel Fjording M; Allinson J; Arfvidsson C; Barroso B; Diczfalusy U; Freeman A; Hickford E; Kandousi H; Katugampola S; Kunz U; Nelson R; Smeraglia J
Editorial comment: AAPS JOURNAL. 2016;18(5):1056-1066

Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity.

Aubry A-F; Dean B; Diczfalusy U; Goodenough A; Iffland A; McLeod J; Weng N; Yang Z
Review: BIOCHIMIE. 2013;95(3):455-460

On the formation and possible biological role of 25-hydroxycholesterol.

Diczfalusy U
Editorial comment: JOURNAL OF LIPID RESEARCH. 2011;52(8):1447-1449

Still another activity by the highly promiscuous enzyme CYP3A4: 25-hydroxylation of cholesterol.

Diczfalusy U; Björkhem I
Letter: NATURE IMMUNOLOGY. 2011;12(7):577

Detecting oxysterols in the human circulation.

Björkhem I; Diczfalusy U; Olsson T; Russell DW; McDonald JG; Wang Y; Griffiths WJ
Review: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2011;71(2):183-189

4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans.

Diczfalusy U; Nylén H; Elander P; Bertilsson L
Book chapter: 2010;p. 99-115

Oxysterols: Potential Biomarkers of Oxidative Stress

Iuliano L; Diczfalusy U
Published paper: ACTA NEUROLOGICA SCANDINAVICA, SUPPLEMENT. 2006;185:43-49

Oxysterols and Alzheimer's disease.

Björkhem I; Heverin M; Leoni V; Meaney S; Diczfalusy U
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2006;7(3):562

Effects of high-dosage itraconazole treatment on synthesis, transport and metabolism of cholesterol in men

Schneider B; Plat J; Gerdsen R; Diczfalusy U; Björkhem I; Neuvonen PJ; Bieber T; Von Bergmann K; L tjohann D
Book chapter: 2005;p. 37-40

Role of CYP3A4 as a cholesterol and bile acid metabolizing enzyme

Bodin K; Diczfalusy U
Book chapter: 2005;p. 219-224

Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients

Marschall H-U; Wagner M; Zollner G; Fickert P; Gumhold J; Silbert D; Diczfalusy U; Benthin L; Grundström R; Gustafsson U; Sahlin S; Einarsson C; Trauner M
Editorial comment: ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. 2004;24(12):2209-2210

24(S),25-epoxycholesterol--a potential friend.

Bjorkhem I; Diczfalusy U
Meeting abstract: JOURNAL OF HEPATOLOGY. 2004;40:93

Comprehensive study of the effects of rifampicin and ursodeoxycholic acid on genes and proteins involved in regulation, transport and detoxification of biliary compounds in gallstone patients

Marschall HU; Wagner M; Zollner G; Fickert P; Gumholdt J; Silbert D; Diczfalusy U; Benthin L; Grundstrom R; Sahlin S; Einarsson C; Trauner M
Review: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2003;364:24-37

Quantitation of receptor ligands by mass spectrometry.

Lund EG; Diczfalusy U
Editorial comment: EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY. 2002;104(7):435-439

Analysis of cholesterol oxidation products in plasma, tissues and food

Bodin K; Diczfalusy U
Review: CURRENT OPINION IN LIPIDOLOGY. 2002;13(3):247-253

Oxysterols in human circulation: which role do they have?

Björkhem I; Meaney S; Diczfalusy U
Published paper: CELL BIOCHEMISTRY AND BIOPHYSICS. 2000;32 Spring:317-324

Acyl-CoA thioesterases belong to a novel gene family of peroxisome proliferator-regulated enzymes involved in lipid metabolism.

Hunt MC; Lindquist PJ; Nousiainen S; Huttunen M; Orii K; Svensson TL; Aoyama T; Hashimoto T; Diczfalusy U; Alexson SE
Meeting abstract: ATHEROSCLEROSIS. 1999;144:121

The lung is the major source of 27-oxygenated cholesterol in the human circulation

Babiker A; Björkhem I; Diczfalusy U
Review: CURRENT OPINION IN LIPIDOLOGY. 1999;10(2):161-165

Removal of cholesterol from extrahepatic sources by oxidative mechanisms.

Björkhem I; Diczfalusy U; Lütjohann D
Published paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 1999;466:195-200

Cloning and regulation of peroxisome proliferator-induced acyl-CoA thioesterases from mouse liver.

Hunt M; Lindquist PJ; Nousiainen S; Svensson TL; Diczfalusy U; Alexson SE
Book chapter: 1999;p. 309-315

MEASUREMENTS OF CHOLESTEROL OXIDES IN FOODS: RESULTS OF AN INTERLABORATORY COMPARISON STUDY

Dutta PC; Caboni MF; Diczfalusy U; Dionisi F; Dzeletovic S; Grandgirard A; Guardiola F; Kumpulainen J; Lebovics VK; Pihlava J-M; Rodriguez-Estrada MT; Ulberth F
Published paper: NEPHROLOGY DIALYSIS TRANSPLANTATION. 1998;13(10):2594-2600

A study of plasmalogen as an index of oxidative stress in patients with chronic renal failure. Evidence of increased oxidative stress in malnourished patients.

Stenvinkel P; Holmberg I; Heimbürger O; Diczfalusy U
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):172

Higher 7 beta-hydroxycholesterol in high cardiovascular risk population

Zieden B; Diczfalusy U
Meeting abstract: ATHEROSCLEROSIS. 1997;134(1-2):217

Lipid peroxidation and progression of carotid atherosclerosis: A prospective 3-year follow-up study

Salonen JT; Nyyssonen K; Salonen R; Luoma J; YlaHerttuala S; Diczfalusy U; Bjorkhem I
Published paper: SCANDINAVIAN JOURNAL OF CLINICAL AND LABORATORY INVESTIGATION, SUPPLEMENT. 1996;226:9-17

Novel pathways for elimination of cholesterol by extrahepatic formation of side-chain oxidized oxysterols.

Diczfalusy U; Lund E; Lütjohann D; Björkhem I
Book chapter: 1996;p. 11-17

OXYSTEROLS AND ATHEROSCLEROSIS - A MINIREVIEW

Björkhem I; Breuer O; Diczfalusy U; Lund E
Book chapter: 1996;p. 11-17

Oxysterols and Atherosclerosis - A Minireview

Björkhem I; Breuer O; Diczfalusy U; Lund E
Book chapter: NEW COMPREHENSIVE BIOCHEMISTRY. 1983;p. 45-94

Chapter 2 The thromboxanes

Granström E; Diczfalusy U; Hamberg M
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