Susanna Myrnerts Höök

Susanna Myrnerts Höök

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Om mig

Susanna Myrnerts Höök is a Paediatric Specialist at the Sachs' Children and Youth Hospital, Stockholm, Sweden and affiliated to the Department of Global Public Health, KI. The last seven years she has been involved in research projects focusing on neonatal resuscitation in Kampala, Uganda, a low-resource setting. The work led her to start a PhD at Bergen University, Norway, September 2016. She defended her thesis May 2021 with the title "Supporting neonatal resuscitation in low-resource settings - innovations and new strategies". https://bora.uib.no/bora-xmlui/handle/11250/2740511

The thesis discusses how best to support non-breathing neonates immediately after birth in low-resource settings using innovations and new strategies. The thesis focused on heart rate assessment using a smartphone app, and airway access for ventilatory support with the use of a laryngeal mask airway (LMA), following its effect on adherence to international neonatal resuscitation guidelines and effect on neonatal mortality and morbidity. 

 

Forskningsbeskrivning

2019 – recent Co-investigator in the NEO-SPIRIT Trial (NEOnatal SuPRaglottic vIetnam Trial) Assessment of a Supraglottic Device Versus Endotracheal Intubation in Neonatal Resuscitation in Vietnam – a Randomised Phase III Clinical Trial (NEO-SPIRIT).

2013 – recent  Development of NeoTap, a new free application for registration of heart rate during resuscitation of newborn babies. Including a manikin-study at Sachs´s Children and Youth hospital in Stockholm, Sweden and an observational study at Mulago Hospital, Kampala, Uganda 

2016 – 2019 NeoSupra trial, a multi-centre, phase III, open-label, randomized clinical trial to evaluate the efficacy of i-gel®supraglottic airway used in neonatal resuscitation in reducing early neonatal mortality and morbidity compared to standard of care face-mask ventilation (FMV) in low income countries. Part of the coordination team, the steering committee and data management team. 

2016 – May 2021 PhD candidate at Bergen University, Norway, Paper I-III are published in Acta Paediatrica, BMJ Paediatrics Open and New England Journal of Medicine. Name of articles planned in thesis:

  • Accurate and fast neonatal heart rate assessment with a smartphone-based application - a manikin study 
  • Smartphone app for neonatal heart rate assessment– an observational study. 
  • A randomized trial of laryngeal mask airway in neonatal resuscitation. 

1999 – 2000  “Arthritis among children of the Shipibo people.”  Pucallpa, Peru, Anders Fasth, Professor of Paediatric Immunology, The Queen Silvia Children's Hospital, Gothenburg, Sweden 

Publications: 

  • Pejovic NJ*, Myrnerts Höök S*, Byamugisha J, Alfvén T, Lubulwa C, Cavallin F, Nankunda J, Ersdal H, Blennow M, Trevisanuto D, Tylleskär T. A Randomized Trial of Laryngeal Mask Airway in Neonatal Resuscitation. N Engl J Med. 2020 Nov 26;383(22):2138-2147. DOI: 10.1056/NEJMoa2005333. PMID: 33252870. *Shared first authorship.
  • Helldén D*, Myrnerts Höök S*, Pejovic NJ, Mclellan D, Lubulwa C, Tylleskär T, Alfven T. Neonatal resuscitation practices in Uganda: a video observational study. BMJ Paediatr Open. 2021 Sep 14;5(1):e001092. DOI: 10.1136/bmjpo-2021-001092. PMID: 34595356; PMCID: PMC8442103. *Shared first authorship.
  • Dempsey, T.; Nguyen, H.L.; Nguyen, H.T.; Bui, X.A.; Pham, P.T.T.; Nguyen, T.K.; Cavallin, F.; Trevisanuto, D.; Myrnerts Höök S, Pejovic, N, Blennow M, Olson L, Vu H, Anh Duy Nguyen AD, and Tobias Alfvén T. Incidence of Intrapartum- Related Events at the Largest Obstetric Hospital in Hanoi, Vietnam: A Retrospective Study. Children 2022, 9(3), 321. https://doi.org/10.3390/children9030321
  • Pejovic NJ, Cavallin F, Mpamize A, Lubulwa C, Myrnerts Höök S, Byamugisha J, Nankunda J, Tylleskär T, Trevisanuto D. Respiratory monitoring during neonatal resuscitation using a supraglottic airway device vs. a face mask. Resuscitation. 2022 Feb;171:107-113. DOI: 10.1016/j.resuscitation.2021.10.025. Epub 2021 Oct 22. PMID: 34695444.
  • Larsson M, Myrnerts Höök S, Mpamize A, et al. Oxygen saturation after birth in resuscitated neonates in Uganda: a video-based observational study. BMJ Paediatrics Open 2022;6:e001225. doi:10.1136/ bmjpo-2021-001225
  • Tylleskär T, Cavallin F, Myrnerts Höök S, Pejovic NJ, Lubulwa C, Byamugisha J, Nankunda J, Trevisanuto D; NeoSupra Trial Team. Outcome of infants with 10 min Apgar scores of 0-1 in a low-resource setting. Arch Dis Child Fetal Neonatal Ed. 2021 Nov 1:fetalneonatal-2021-322545. DOI: 10.1136/archdischild-2021-322545. Epub ahead of print. PMID: 34725104.
  • Myrnerts Höök S, Pejovic NJ, Cavallin F, Lubulwa C, Byamugisha J, Nankunda J, Tylleskär T, Alfven T. Smartphone app for neonatal heart rate assessment: an observational study. BMJ Paediatr Open. 2020 Jul 22;4(1):e000688. DOI: 10.1136/bmjpo-2020-000688. PMID: 32760813; PMCID: PMC7381998.
  • Pejovic NJ, Myrnerts Höök S, Byamugisha J, Alfvén T, Lubulwa C, Cavallin F, Nankunda J, Ersdal H, Segafredo G, Blennow M, Trevisanuto D, Tylleskär T. Neonatal resuscitation using a supraglottic airway device for improved mortality and morbidity outcomes in a low-income country: study protocol for a randomized trial. Trials. 2019 Jul 19;20(1):444. DOI: 10.1186/s13063-019-3455-8. PMID: 31324213; PMCID: PMC6642595.
  • Myrnerts Höök S, Namusoko S, Tylleskär T, Byamugisha J, Bergström A. Midwives´ capability, opportunity and motivation to perform evidence-based neonatal resuscitation in a low resource setting: a qualitative study. The Pediatric Academic Societies (PAS) meeting 2019; 2019.
  • Myrnerts Höök S, Pejovic NJ, Marrone G, Tylleskär T, Alfvén T. Accurate and fast neonatal heart rate assessment with a smartphone-based application - a manikin study. Acta Paediatr. 2018 Mar 31;107(9):1548–54. DOI: 10.1111/apa.14350. Epub ahead of print. PMID: 29604115; PMCID: PMC6120499.
  • Alfvén T, Helldén D, Pejovic N, Myrnerts Höök S, Tylleskär T. Apropå! Globala hälsosystem och vikten av innovationer. Läkartidningen 2018:115. PMID: 29360124
  • Pejovic NJ, Trevisanuto D, Lubulwa C, Myrnerts Höök S, Cavallin F, Byamugisha J, Nankunda J, Tylleskär T. Neonatal resuscitation using a laryngeal mask airway: a randomised trial in Uganda. Arch Dis Child. 2018 Mar;103(3):255-260. DOI: 10.1136/archdischild-2017-312934. Epub 2017 Sep 14. PMID: 28912163; PMCID: PMC5865513.

Pedagogiska meriter

  • 2014 -recent  Teacher for medical students at Karolinska Institute, Stockholm, Sweden 
  • 2016- recent  Master trainer Helping Babies Breathe neonatal resuscitation training in Uganda     
  • 2015              Participate in organizing training in Essential Newborn Care for MSF doctors  

Utbildning

  • PhD candidate: 2016-May 2021 University of Bergen, Norway, Professor Thorkild Tylleskär, affiliated to Karolinska Institutet
  • 2015 Certified Specialist in Paediatrics
  • Residency: 2010-2015 Paediatrics, Sachs' Children and Youth Hospital, Stockholm, Sweden
  • Residency:2005-2010 General Medicine, S:t Erik health centre, Stockholm, Sweden
  • Internship: 2002-2005 Internal Medicine, Geriatrics, Surgery, General Medicine, Psychiatry, Södersjukhuset, Sweden
  • Medical/Graduate:
  • 1996-2002 Doctor of Medicine, University of Gothenburg, The Sahlgrenska Academy Gothenburg, Sweden
  • Licensure/Certification1996-2002 M.D. Sweden

Languages: Swedish, native tongue – English/Spanish/French, fluently spoken and written  

 

Akademiska priser och utmärkelser

May 2021: Publication of the year 2020 at the Department of Global Public Health and Primary Care at University of Bergen, Norway, for the article: "A randomized trial of laryngeal mask airway in neonatal resuscitation". The New England Journal of Medicine 2020;383:2138-47. Doi:10.1056/NEJMoa2005333.

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