Stefanie Prast-Nielsen

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Senior Research Specialist in Multiomics, Machine Learning and Data
Integration at the Centre for Translational Microbiome Research
PhD in Medical Biochemistry
For more information, please check out the English version of the website:
https://staff.ki.se/people/stepra [1]
[1] https://staff.ki.se/people/stepra

Artiklar

Journal article: CELL REPORTS. 2023;42(12):113570

Fecal transfers from children on the ketogenic diet mimic the anti-seizure effect in mice.

Prast-Nielsen S
Article: JOURNAL OF CROHNS & COLITIS. 2023;17(3):418-432

Mucosal and Plasma Metabolomes in New-onset Paediatric Inflammatory Bowel Disease: Correlations with Disease Characteristics and Plasma Inflammation Protein Markers.

Nyström N; Prast-Nielsen S; Correia M; Globisch D; Engstrand L; Schuppe-Koistinen I; Halfvarson J
Article: EBIOMEDICINE. 2022;80:104061

Higher levels of Bifidobacteria and tumor necrosis factor in children with drug-resistant epilepsy are associated with anti-seizure response to the ketogenic diet.

Dahlin M; Singleton SS; David JA; Basuchoudhary A; Wickström R; Mazumder R; Prast-Nielsen S
Article: JOURNAL OF DERMATOLOGICAL SCIENCE. 2022;106(3):132-140

Influence of FLG loss-of-function mutations in host-microbe interactions during atopic skin inflammation.

Oláh P; Szlávicz E; Kuchner M; Nemmer J; Zeeuwen P; Lefèvre-Utile A; Fyhrquist N; Prast-Nielsen S; Skoog T; Serra A; Rodríguez E; Raap U; Meller S; Gyulai R; Hupé P; Kere J; Levi-Schaffer F; Tsoka S; Alexander H; Nestle FO; Schröder JM; Weidinger S; van den Bogaard E; Soumelis V; Greco D; Barker J; Lauerma A; Ranki A; Andersson B; Alenius H; Homey B
Article: ALLERGY. 2022;77(5):1486-1498

Transcriptome-based identification of novel endotypes in adult atopic dermatitis.

Lefèvre-Utile A; Saichi M; Oláh P; Delord M; Homey B; Soumelis V; MAARS consortium
Article: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES. 2021;111:313-321

Alterations of gut microbiota in patients with active pulmonary tuberculosis in China: a pilot study.

Shi W; Hu Y; Ning Z; Xia F; Wu M; Hu YOO; Chen C; Prast-Nielsen S; Xu B
Article: BMC PULMONARY MEDICINE. 2019;19(1):211

Longitudinal profiling of gut microbiome among tuberculosis patients under anti-tuberculosis treatment in China: protocol of a prospective cohort study.

Shi W; Hu Y; Zheng X; Ning Z; Wu M; Xia F; Prast-Nielsen S; Hu YOO; Xu B
Article: NATURE COMMUNICATIONS. 2019;10(1):4703

Microbe-host interplay in atopic dermatitis and psoriasis.

Fyhrquist N; Muirhead G; Prast-Nielsen S; Jeanmougin M; Olah P; Skoog T; Jules-Clement G; Feld M; Barrientos-Somarribas M; Sinkko H; van den Bogaard EH; Zeeuwen PLJM; Rikken G; Schalkwijk J; Niehues H; Däubener W; Eller SK; Alexander H; Pennino D; Suomela S; Tessas I; Lybeck E; Baran AM; Darban H; Gangwar RS; Gerstel U; Jahn K; Karisola P; Yan L; Hansmann B; Katayama S; Meller S; Bylesjö M; Hupé P; Levi-Schaffer F; Greco D; Ranki A; Schröder JM; Barker J; Kere J; Tsoka S; Lauerma A; Soumelis V; Nestle FO; Homey B; Andersson B; Alenius H
Article: BRITISH JOURNAL OF DERMATOLOGY. 2019;181(3):572-579

Investigation of the skin microbiome: swabs vs. biopsies.

Prast-Nielsen S; Tobin A-M; Adamzik K; Powles A; Hugerth LW; Sweeney C; Kirby B; Engstrand L; Fry L
Article: NPJ BIOFILMS AND MICROBIOMES. 2019;5(1):5

The ketogenic diet influences taxonomic and functional composition of the gut microbiota in children with severe epilepsy.

Lindefeldt M; Eng A; Darban H; Bjerkner A; Zetterström CK; Allander T; Andersson B; Borenstein E; Dahlin M; Prast-Nielsen S
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2011;50(9):1114-1123

Inhibition of thioredoxin reductase 1 by porphyrins and other small molecules identified by a high-throughput screening assay.

Prast-Nielsen S; Dexheimer TS; Schultz L; Stafford WC; Cheng Q; Xu J; Jadhav A; Arnér ESJ; Simeonov A
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2010;49(11):1765-1778

Noble metal targeting of thioredoxin reductase--covalent complexes with thioredoxin and thioredoxin-related protein of 14 kDa triggered by cisplatin.

Prast-Nielsen S; Cebula M; Pader I; Arnér ESJ
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2009;47(11):1661-1671

High levels of thioredoxin reductase 1 modulate drug-specific cytotoxic efficacy.

Eriksson SE; Prast-Nielsen S; Flaberg E; Szekely L; Arnér ESJ
Article: JOURNAL OF MEDICINAL CHEMISTRY. 2009;52(20):6474-6483

Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.

Rai G; Sayed AA; Lea WA; Luecke HF; Chakrapani H; Prast-Nielsen S; Jadhav A; Leister W; Shen M; Inglese J; Austin CP; Keefer L; Arnér ESJ; Simeonov A; Maloney DJ; Williams DL; Thomas CJ
Article: PLOS ONE. 2008;3(4):e1846

Cell death by SecTRAPs: thioredoxin reductase as a prooxidant killer of cells.

Anestål K; Prast-Nielsen S; Cenas N; Arnér ESJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(9):5593-5603

Interactions of nitroaromatic compounds with the mammalian selenoprotein thioredoxin reductase and the relation to induction of apoptosis in human cancer cells.

Cenas N; Prast S; Nivinskas H; Sarlauskas J; Arnér ESJ
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;327(3):774-779

Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release.

Enoksson M; Fernandes AP; Prast S; Lillig CH; Holmgren A; Orrenius S

Alla övriga publikationer

Letter: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2022;206(12):1564-1567

Metatranscriptomics of Nasopharyngeal Microbiota and Host Distinguish between Pneumonia and Health.

Nannapaneni P; Sundh J; Prast-Nielsen S; Rhedin S; Örtqvist Å; Naucler P; Henriques-Normark B
Review: PROGRESS IN NUCLEIC ACID RESEARCH AND MOLECULAR BIOLOGY. 2020;176:141-178

Bioinformatics and machine learning in gastrointestinal microbiome research and clinical application.

Hopson LM; Singleton SS; David JA; Basuchoudhary A; Prast-Nielsen S; Klein P; Sen S; Mazumder R
Review: EBIOMEDICINE. 2019;44:741-746

The gut microbiome and epilepsy.

Dahlin M; Prast-Nielsen S
Review: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2011;1810(12):1262-1271

Thioredoxin glutathione reductase: its role in redox biology and potential as a target for drugs against neglected diseases.

Prast-Nielsen S; Huang H-H; Williams DL

Anställningar

Senior Forskningsspecialist, Institutionen för mikrobiologi, tumör- och cellbiologi, Karolinska Institutet, 2023-

Examina och utbildning

Docent, Mikrobiologi inom det medicinska området, Karolinska Institutet, 2023
Medicine Doktorsexamen, Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet, 2009

Om mig

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI