Rongrong Fan

Rongrong Fan

Senior Forskare | Docent
E-postadress: rongrong.fan@ki.se
Besöksadress: Blickagången 16, 14152 Flemingsberg
Postadress: H7 Medicin, Huddinge, H7 BioNut Fan, 171 77 Stockholm
Del av:

Om mig

  • Lab page: https://ki.se/en/bionut/liver-and-monocyte-remodelling-in-non-alcoholic-fatty-liver-disease-and-cardiovascular Research grants: Swedish research council (Vetenskapsrådet) EFSD / Novo Nordisk Future Leaders Award Cancerfonden The Rolf Luft Grant for Instrumentation SRP diabetes KI faculty-funded senior researcher CIMED NOVO NORDISK Foundation KI Doctoral funding Åke Wibergs Stiftelse Diabetes Wellness Sverige Foundation EFSD / Lilly research fellowship KI foundation Commission of trust: Editorial board: Frontiers in Endocrinology 2021-. Guest editor: Frontiers in Endocrinology 2020-2021. Steering Committee: lipoprotein research networks in KI south campus (supported by CIMED). Grant evaluation task for: ANR, VR, FWF, KID, etc Invited reviewer in: Nat Com, JCI, eLife, JBC, FASEB J, Diabetologia, etc. Organizing committee and chairs for domestic and international conferences.

Forskningsbeskrivning

  • My research combines the phenotypic/clinical analysis with multi-OMICs approaches to understand the fundamental question of how over-nutritional signals alter chromatin remodelling to promote metabolic disease development. We have so far analyzed different patient samples in the transcriptomic, cistromic and epigenomic levels and identified a group of interesting candidates involved in species-conserved and disease-relevant regulation of glucose and lipid metabolism. Of particular interest is the transcription factor coregulator GPS2, the dysregulation of which is associated with de-repressed inflammation and impaired lipid oxidation pathways, leading to type 2 diabetes and liver disease progression. The ongoing research activity involves further investigation of the coregulator-based mechanisms in the genomic and epigenomic level in various disease contexts. Understanding such pathways is crucial for better deciphering disease mechanisms which is ultimately required for identifying novel targets with diagnostic and intervention potential.

Undervisning

  • Main supervisor of 3 ongoing PhD student and 1 postdoc Cosupervisor of 1 ongoing PhD student and 2 completed PhD students Project supervisor of 5 bachelor students and 2 Master student More than 200 teaching hours in Bachelor, Master and PhD courses Master level course director Professional university pedagogy training (equivalent to more than 5 weeks)

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

  • Senior Forskare, Medicin, Huddinge, Karolinska Institutet, 2024-
  • Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2024-2024
  • Senior Forskare, Biovetenskaper och näringslära, Karolinska Institutet, 2022-2024

Examina och utbildning

  • Docent, Cell- och molekylärbiologi, Karolinska Institutet, 2022

Nyheter från KI

Kalenderhändelser från KI