Pernilla Lång

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Populärvetenskap och samverkan

Artiklar

Article: IMMUNOLOGY. 2024;171(4):583-594

Macrophage expressed tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis progression.

Bergwik J; Bhongir RKV; Padra M; Adler A; Olm F; Lång P; Lindstedt S; Andersson G; Egesten A; Tanner L
Article: BONE REPORTS. 2023;19:101697

RANKL-dependent osteoclast differentiation and gene expression in bone marrow-derived cells from adult mice is sexually dimorphic.

Desai S; Lång P; Näreoja T; Windahl SH; Andersson G
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:1079775

Tartrate resistant acid phosphatase 5 (TRAP5) mediates immune cell recruitment in a murine model of pulmonary bacterial infection.

Tanner L; Bergwik J; Bhongir RKV; Puthia M; Lång P; Ali MN; Welinder C; Önnerfjord P; Erjefält JS; Palmberg L; Andersson G; Egesten A
Article: FEBS LETTERS. 2021;595(20):2616-2627

Tartrate-resistant acid phosphatase type 5/ACP5 promotes cell cycle entry of 3T3-L1 preadipocytes by increasing IGF-1/Akt signaling.

Lång P; Patlaka C; Andersson G
Article: EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY. 2020;25(5):1387-1397

Intensive weight gain therapy in patients with anorexia nervosa results in improved serum tartrate-resistant acid phosphatase (TRAP) 5a and 5b isoform protein levels.

Patlaka C; Tubic B; Lång P; Paulie S; Swolin-Eide D; Magnusson P; Andersson G
Article: CALCIFIED TISSUE INTERNATIONAL. 2020;106(2):194-207

A Novel Sandwich ELISA for Tartrate-Resistant Acid Phosphatase 5a and 5b Protein Reveals that Both Isoforms are Secreted by Differentiating Osteoclasts and Correlate to the Type I Collagen Degradation Marker CTX-I In Vivo and In Vitro.

Mira-Pascual L; Patlaka C; Desai S; Paulie S; Näreoja T; Lång P; Andersson G
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(2):E538-538

A Sub-Clone of RAW264.7-Cells Form Osteoclast-Like Cells Capable of Bone Resorption Faster than Parental RAW264.7 through Increased De Novo Expression and Nuclear Translocation of NFATc1.

Mira-Pascual L; Tran AN; Andersson G; Näreoja T; Lång P
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2019;234(9):16503-16516

Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing.

Amirhosseini M; Bernhardsson M; Lång P; Andersson G; Flygare J; Fahlgren A
Article: BIOMARKERS. 2017;22(8):764-774

The adipokine tartrate-resistant acid phosphatase 5a in serum correlates to adipose tissue expansion in obesity.

Patlaka C; Mira Pascual L; Paulie S; Henriksson A-F; Arner P; Lång P; Andersson G
Article: PLOS ONE. 2017;12(8):e0182904

Increased amount of phosphorylated proinflammatory osteopontin in rheumatoid arthritis synovia is associated to decreased tartrate-resistant acid phosphatase 5B/5A ratio.

Luukkonen J; Pascual LM; Patlaka C; Lång P; Turunen S; Halleen J; Nousiainen T; Valkealahti M; Tuukkanen J; Andersson G; Lehenkari P
Journal article: BONE ABSTRACTS. 2016

RAW264.7 subclones - an in vitro model for osteoclast heterogeneity?

Mira-Pascual L; Lang P; Andersson G
Journal article: BONE ABSTRACTS. 2016

Development of a novel sandwich ELISA to quantify human Tartrate Resistant Acid Phosphatase (TRAP) isoforms 5a and 5b protein in one and the same sample

Patlaka C; Mira-Pascual L; Paulie S; Lang P; Andersson G
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2014;454(3):446-452

The growth factor-like adipokine tartrate-resistant acid phosphatase 5a interacts with the rod G3 domain of adipocyte-produced nidogen-2.

Patlaka C; Mai HA; Lång P; Andersson G
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2014;1843(3):495-507

Caveolae-mediated endocytosis of the glucosaminoglycan-interacting adipokine tartrate resistant acid phosphatase 5a in adipocyte progenitor lineage cells.

Patlaka C; Norgård M; Paulie S; Nordvall-Bodell A; Lång P; Andersson G
Article: DIABETOLOGIA. 2013;56(8):1792-1801

Semaphorin 3C is a novel adipokine linked to extracellular matrix composition.

Mejhert N; Wilfling F; Esteve D; Galitzky J; Pellegrinelli V; Kolditz C-I; Viguerie N; Tordjman J; Näslund E; Trayhurn P; Lacasa D; Dahlman I; Stich V; Lång P; Langin D; Bouloumié A; Clément K; Rydén M
Article: CELLS TISSUES ORGANS. 2012;196(1):68-81

Transgenic overexpression of tartrate-resistant acid phosphatase is associated with induction of osteoblast gene expression and increased cortical bone mineral content and density.

Gradin P; Hollberg K; Cassady AI; Lång P; Andersson G
Article: INTERNATIONAL JOURNAL OF OBESITY. 2011;35(12):1502-1510

Expression and secretion of the novel adipokine tartrate-resistant acid phosphatase from adipose tissues of obese and lean women.

Lång P; Zakaroff-Girard A; Wåhlén K; Andersson J; Olsson T; Bambace C; Jocken J; Bouloumié A; Andersson G; Arner P
Article: HISTOCHEMISTRY AND CELL BIOLOGY. 2009;132(6):599-612

Induction and cellular expression of tartrate resistant acid phosphatase during dextran sodium sulphate induced colitis in rats.

Lång P; Lange S; Delbro D; Andersson G
Article: PLOS ONE. 2008;3(3):e1713

Monomeric tartrate resistant acid phosphatase induces insulin sensitive obesity.

Lång P; van Harmelen V; Rydén M; Kaaman M; Parini P; Carneheim C; Cassady AI; Hume DA; Andersson G; Arner P
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(31):28370-28381

Proteolytic excision of a repressive loop domain in tartrate-resistant acid phosphatase by cathepsin K in osteoclasts.

Ljusberg J; Wang Y; Lång P; Norgård M; Dodds R; Hultenby K; Ek-Rylander B; Andersson G
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2005;62(7-8):905-918

Differential expression of monomeric and proteolytically processed forms of tartrate-resistant acid phosphatase in rat tissues.

Lång P; Andersson G
Article: NATURE CELL BIOLOGY. 2004;6(6):523-531

Myosin-X provides a motor-based link between integrins and the cytoskeleton.

Zhang H; Berg JS; Li Z; Wang Y; Lång P; Sousa AD; Bhaskar A; Cheney RE; Strömblad S
Article: JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY. 2001;49(3):379-396

Expression and distribution of tartrate-resistant purple acid phosphatase in the rat nervous system.

Lång P; Schultzberg M; Andersson G
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Alla övriga publikationer

Conference publication: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. 2019;199:a4519

Effects of Cigarette Smoke Exposure on Tartrate-Resistant Acid Phosphatase Expression in Murine Lung Tissue

van der Veen A; Lang P; de Jager MH; Andersson G; Melgert BN
Conference publication: FEBS JOURNAL. 2012;279:544

TRAP 5a interacts with cells of mesenchymal lineage and affects their differentiation

Patlaka C; Mai HA; Nordvall-Bodell A; Lang P; Andersson G
Published conference paper: JOURNAL OF BONE AND MINERAL RESEARCH. 2003;18(10):1912-1915

TRACP as an osteopontin phosphatase.

Andersson G; Ek-Rylander B; Hollberg K; Ljusberg-Sjölander J; Lång P; Norgård M; Wang Y; Zhang S-J
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 2000;15:S395

Cellular localization of tartrate resistant acid phosphatase and osteopontin in rat lymphatic organs.

Lång P; Andersson G
Conference publication: JOURNAL OF BONE AND MINERAL RESEARCH. 1999;14:S486

Expression and distribution of tartrate-resistant purple acid phosphatase in the rat nervous system.

Lång P; Schultzberg M; Andersson G

Anställningar

Assisterande Lektor, Laboratoriemedicin, Karolinska Institutet, 2022-

Examina och utbildning

FILOSOFIE DOKTOR, Institutionen för laboratoriemedicin, Karolinska Institutet, 2007
Medicine Kandidatexamen, Karolinska Institutet, 1998

Uppdrag

Utbildningsansvarig, Biomedicinska analytikerprogrammet, Laboratoriemedicin, Karolinska Institutet, 2023-
Utbildningsansvarig, Magisterprogram i biomedicinsk laboratorievetenskap, Laboratoriemedicin, Karolinska Institutet, 2023-
Projektledare, Utveckling av ny utbildningsplan för biomedicinska analytikerprogrammet, Laboratoriemedicin, Karolinska Institutet, 2021-2023

Handledare

Laia Mira Pascual, Role of tartrate-resistant acid phosphatase in bone remodeling, https://openarchive.ki.se/xmlui/handle/10616/46930
Suchita Desai, The role of mechanical loading, sex and TRAP/ACP5 on bone properties, https://openarchive.ki.se/xmlui/handle/10616/48681
Christina Patlaka, Tartrate resistant acid phosphatase 5a : a potential regulator of adipocyte cell number and differentiation in white adipose tissue, https://openarchive.ki.se/xmlui/handle/10616/44563

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