Forskningsbeskrivning
Utvalda publikationer:
Jeliazkova N, Apostolova MD, Andreoli C, Barone F, Barrick A, Battistelli C, Bossa C, Botea-Petcu A, Châtel A, De Angelis I, Dusinska M, El Yamani N, Gheorghe D, Giusti A, Gómez-Fernández P, Grafström R, Gromelski M, Jacobsen NR, Jeliazkov V, Jensen KA, Kochev N, Kohonen P, Manier N, Mariussen E, Mech A, Navas JM, Paskaleva V, Precupas A, Puzyn T, Rasmussen K, Ritchie P, Llopis IR, Rundén-Pran E, Sandu R, Shandilya N, Tanasescu S, Haase A, Nymark P. Towards FAIR nanosafety data. Nat Nanotechnol. 2021 May 20. doi: 10.1038/s41565-021-00911-6.
Nymark P, Karlsson HL, Halappanavar S, Vogel U. Adverse Outcome Pathway development for assessment of lung carcinogenicity by nanoparticles. Frontiers in Toxicology, 29 April 2021. doi: 10.3389/ftox.2021.653386
Nymark P, Sachana M, Batista-Leite S, Sund J, Krebs C.E., Sullivan K, Edwards S, Viviani L, Willett K, Landesmann B, Wittwehr C. Systematic Organization of COVID-19 Data Supported by the Adverse Outcome Pathway Framework. Frontiers in Public Health, 19 May 2021, doi: 10.3389/fpubh.2021.638605
Halappanavar S, van den Brule S, Nymark P, Gaté L, Seidel C, Valentino S, Zhernovkov V, Høgh Danielsen P, De Vizcaya A, Wolff H, Stöger T, Boyadziev A, Poulsen SS, Sørli JB, Vogel U. Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale. Part Fibre Toxicol. 2020 May 25;17(1):16. doi: 10.1186/s12989-020-00344-4.
Nymark P, Bakker M, Dekkers S, Franken R, Fransman W, García-Bilbao A, Greco D, Gulumian M, Hadrup N, Halappanavar S, Hongisto V, Hougaard KS, Jensen KA, Kohonen P, Koivisto AJ, Dal Maso M, Oosterwijk T, Poikkimäki M, Rodriguez-Llopis I, Stierum R, Sørli JB, Grafström R. Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices. Small. 2020 Feb;16(6):e1904749. doi: 10.1002/smll.201904749. Epub 2020 Jan 8.
Soeteman-Hernandez LG, Apostolova MD, Bekker C, Dekkers S, Grafström RC, Groenewold M, Handzhiyski Y, Herbeck-Engel P, Hoehener K, Karagkiozaki V, Kelly S, Kraegeloh A, Logothetidis S, Micheletti C, Nymark P, Oomen A, Oosterwijk T, Rodríguez-LLopis I, Sabella S, Sanchez Jiménez A, Sips A, Suarez-Merino B, Tavernaro I, van Engelen J, Wijnhoven SWP, Noorlander CW. Safe innovation approach: Towards an agile system for dealing with innovations. Materials Today Communications, Volume 20, 2019, 100548, ISSN 2352-4928, doi: 10.1016/j.mtcomm.2019
Giusti A, Atluri R, Tsekovska R, Gajewicz A, Apostolova MD, Battistelli CL, Bleeker EAJ, Bossa C, Bouillard j, Dusinska M, Gómez-Fernández P, Grafström R, Gromelski M, Handzhiyski Y, Jacobsen NR, Jantunen P, Jensen KA, Mech A, Navas JM, Nymark P, Oomen AG, Puzyn T, Rasmussen K, Riebeling C, Rodriguez-Llopis I, Sabella S, Riego Sintes J, Suarez-Merino B, Tanasescu S, Wallin H, Haase A. Nanomaterial grouping: Existing approaches and future recommendations. NanoImpact, Volume 16, 2019, 100182, ISSN 2452-0748, doi: 10.1016/j.impact.2019.100182
Nymark P, Kohonen P, Hongisto V, Grafström RC. Toxic and Genomic Influences of Inhaled Nanomaterials as a Basis for Predicting Adverse Outcome. Ann Am Thorac Soc. 2018 Apr;15(Suppl 2):S91-S97. doi: 10.1513/AnnalsATS.201706-478MG.
Nymark P, Rieswijk L, Ehrhart F, Jeliazkova N, Tsiliki G, Sarimveis H, Evelo CT, Hongisto V, Kohonen P, Willighagen E, Grafström RC. A Data Fusion Pipeline for Generating and Enriching Adverse Outcome Pathway Descriptions. Toxicol Sci. 2018 Mar 1;162(1):264-275. doi: 10.1093/toxsci/kfx252.
Nymark P, Wijshoff P, Cavill R, van Herwijnen M, Coonen ML, Claessen S, Catalán J, Norppa H, Kleinjans JC, Briedé JJ. Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells. Nanotoxicology, 2015. 9(5): p. 624-635. doi: 10.3109/17435390.2015.1017022
Nymark P, Guled M, Borze I, Faisal A, Lahti L, Salmenkivi K, Kettunen E, Anttila S, Knuutila S. Integrative Analysis of microRNA, mRNA and aCGH Data Reveals Asbestos-Related Changes in Non-Small Cell Lung Cancer. Genes, Chromosom. Cancer, 2011. 50(8):585-97. doi: 10.1002/gcc.20880
Nymark P, Wikman H, Hienonen-Kempas T, Anttila S. Molecular and genetic changes in asbestos-related lung cancer. Cancer Lett. 2008. 265(1):1-15. Doi: 10.1016/j.canlet.2008.02.043