Moustapha Hassan

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Moustapha Hassan utnämndes till professor i transplantationsforskning vid institutionen för laboratoriemedicin 2013. Hans forskning handlar om förbättrad överlevnad och livskvalitet hos cancerpatienter som behandlas med cytostatika och stamcellstransplantation.

Artiklar

Article: TRANSPLANTATION AND CELLULAR THERAPY. 2023;29(9):581.e1-581.e8

Interaction Between High-Dose Intravenous Busulfan and Post-Transplantation Cyclophosphamide on Hemorrhagic Cystitis After Allogeneic Hematopoietic Cell Transplantation.

Santos Carreira A; Salas MQ; Remberger M; Novitzky-Basso I; Law AD; Lam W; Pasic I; Mazzulli T; Cserti-Gazdewich C; Kim DDH; Michelis FV; Viswabandya A; Gerbitz A; Lipton JH; Kumar R; Hassan M; Mattsson J
Article: CELL JOURNAL. 2023;25(8):524-535

Umbilical Cord Blood-Derived Monocytes as A Reliable Source of Functional Macrophages for Biomedical Research.

Torabi S; Zarrabi M; Hossein-Khannazer N; Lotfinia M; Nouri M; Gramignoli R; Hassan M; Vosough M
Article: NANO TODAY. 2023;50:101824

NIR light-driven photocatalytic NAD(P)H oxidation and H2O2 generation in situ for enhanced chemodynamic therapy and immune response

Zhang C; Huang J; Guo X; Da X; Dai Z; Hassan M; Yu Y; Wang X; Zhou Q
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2023;11(2):e005691

Tuned activation of MSLN-CAR T cells induces superior antitumor responses in ovarian cancer models.

Schoutrop E; Poiret T; El-Serafi I; Zhao Y; He R; Moter A; Henriksson J; Hassan M; Magalhaes I; Mattsson J
Article: PHYTOMEDICINE. 2023;110:154634

Celastrol targets the ChREBP-TXNIP axis to ameliorates type 2 diabetes mellitus.

Zhou D; Li X; Xiao X; Wang G; Chen B; Song Y; Liu X; He Q; Zhang H; Wu Q; Zhang L; Wu L; Shen Z; Hassan M; Zhao Y; Zhou W
Article: MOLECULAR AND CELLULAR BIOCHEMISTRY. 2023;478(1):23-37

Novel antigens for targeted radioimmunotherapy in hepatocellular carcinoma.

Pourhamzeh M; Asadian S; Mirzaei H; Minaei A; Shahriari E; Shpichka A; Es HA; Timashev P; Hassan M; Vosough M
Article: JOURNAL OF BIOMEDICAL NANOTECHNOLOGY. 2023;19(1):28-35

Perfluorocarbon-Encapsulated Porphyrin-Lipid Nanoparticles as a Photoactive Pyroptosis Inducer for Cancer Therapy

Lin X; Jiang X; Xu Y; Liu R; Zhang N; Li R; Xiang H; Zhao C; Zhao Z; Zeng W; Qu S; Tan X; Cheng C; Chen X; Wang M; Liu Y; Liu L; Zhao Y; Dai Z; Hassan M; Sun D
Article: STEM CELLS INTERNATIONAL. 2022;2022:1850305-14

Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells.

Miri-Lavasani Z; Torabi S; Solhi R; Shokouhian B; Afsharian P; Heydari Z; Piryaei A; Farzaneh Z; Hossein-Khannazer N; Es HA; Zahmatkesh E; Nussler A; Hassan M; Najimi M; Vosough M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2022;106:108587

Novel insights in CAR-NK cells beyond CAR-T cell technology; promising advantages.

Ebrahimiyan H; Tamimi A; Shokoohian B; Minaei N; Memarnejadian A; Hossein-Khannazer N; Hassan M; Vosough M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2022;28(4):196-202

Association Between the Magnitude of Intravenous Busulfan Exposure and Development of Hepatic Veno-Occlusive Disease in Children and Young Adults Undergoing Myeloablative Allogeneic Hematopoietic Cell Transplantation.

Bognàr T; Bartelink IH; Egberts TCG; Rademaker CMA; Versluys AB; Slatter MA; Kletzel M; Nath CE; Cuvelier GDE; Savic RM; Dvorak C; Long-Boyle JR; Cowan MJ; Bittencourt H; Bredius RGM; Güngör T; Shaw PJ; Ansari M; Hassan M; Krajinovic M; Hempel G; Marktel S; Chiesa R; Théoret Y; Lund T; Orchard PJ; Wynn RF; Boelens JJ; Lalmohamed A
Article: BMJ GLOBAL HEALTH. 2022;7(4):e008143

Derivation and validation of a novel risk assessment tool to identify children aged 2-59 months at risk of hospitalised pneumonia-related mortality in 20 countries.

Rees CA; Colbourn T; Hooli S; King C; Lufesi N; McCollum ED; Mwansambo C; Cutland C; Madhi SA; Nunes M; Matthew JL; Addo-Yobo E; Chisaka N; Hassan M; Hibberd PL; Jeena PM; Lozano JM; MacLeod WB; Patel A; Thea DM; Nguyen NTV; Kartasasmita CB; Lucero M; Awasthi S; Bavdekar A; Chou M; Nymadawa P; Pape J-W; Paranhos-Baccala G; Picot VS; Rakoto-Andrianarivelo M; Rouzier V; Russomando G; Sylla M; Vanhems P; Wang J; Asghar R; Banajeh S; Iqbal I; Maulen-Radovan I; Mino-Leon G; Saha SK; Santosham M; Singhi S; Basnet S; Strand TA; Bhatnagar S; Wadhwa N; Lodha R; Aneja S; Clara AW; Campbell H; Nair H; Falconer J; Qazi SA; Nisar YB; Neuman MI; World Health Organization PREPARE study group
Article: CELLS. 2022;11(2):305

Rhenium Perrhenate (188ReO4) Induced Apoptosis and Reduced Cancerous Phenotype in Liver Cancer Cells.

Asadian S; Piryaei A; Gheibi N; Aziz Kalantari B; Reza Davarpanah M; Azad M; Kapustina V; Alikhani M; Moghbeli Nejad S; Keshavarz Alikhani H; Mohamadi M; Shpichka A; Timashev P; Hassan M; Vosough M
Article: NPJ BREAST CANCER. 2022;8(1):2

Endoplasmic reticulum stress inhibits AR expression via the PERK/eIF2α/ATF4 pathway in luminal androgen receptor triple-negative breast cancer and prostate cancer.

Li X; Zhou D; Cai Y; Yu X; Zheng X; Chen B; Li W; Zeng H; Hassan M; Zhao Y; Zhou W
Article: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(1):42

COL-3-Induced Molecular and Ultrastructural Alterations in K562 Cells.

Fares M; Oerther S; Hultenby K; Gubrianska D; Zhao Y; Abedi-Valugerdi M; Hassan M
Article: CANCER RESEARCH. 2021;81(11):3022-3035

Mesothelin-Specific CAR T Cells Target Ovarian Cancer.

Schoutrop E; El-Serafi I; Poiret T; Zhao Y; Gultekin O; He R; Moyano-Galceran L; Carlson JW; Lehti K; Hassan M; Magalhaes I; Mattsson J
Article: INTERNATIONAL JOURNAL OF PHARMACEUTICS. 2021;601:120588

Biodistribution of fluorescence-labelled EGF protein from slow release NanoZolid depots in mouse.

Grudén S; Brunmark C; Holmqvist B; Brenndörfer ED; Johansson M; Liu J; Zhao Y; Axén N; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2021;56(4):807-817

Vitamin D levels and busulphan kinetics in patients undergoing hematopoietic stem cell transplantation, a multicenter study.

El-Serafi A; He R; Zheng W; Benkossou F; Oerther S; Zhao Y; Mellgren K; Gustafsson B; Heilmann C; Kanerva J; Lotfi K; Toporski J; Sundin M; Höglund M; Mattsson J; El-Serafi I; Hassan M
Article: SCIENTIFIC REPORTS. 2021;11(1):2707

Cyclophosphamide exposure assessed with the biomarker phosphoramide mustard-hemoglobin in breast cancer patients: The TailorDose I study.

Gernaat SAM; von Stedingk H; Hassan M; Nilsson HP; Rodriguez-Wallberg KA; Hedayati E; Rydberg P
Article: ACS APPLIED MATERIALS & INTERFACES. 2020;12(48):53665-53681

Multimodal Imaging of Pancreatic Ductal Adenocarcinoma Using Multifunctional Nanoparticles as Contrast Agents.

Zhao Y; Ye F; Brismar TB; Li X; He R; Heuchel R; El-Sayed R; Feliu N; Zheng W; Oerther S; Dutta J; Parak WJ; Muhammed M; Hassan M
Article: PHARMACOLOGICAL RESEARCH. 2020;160:105070

β-radiating radionuclides in cancer treatment, novel insight into promising approach.

Asadian S; Mirzaei H; Kalantari BA; Davarpanah MR; Mohamadi M; Shpichka A; Nasehi L; Es HA; Timashev P; Najimi M; Gheibi N; Hassan M; Vosough M
Article: BLOOD ADVANCES. 2020;4(9):1998-2010

Targeted busulfan-based reduced-intensity conditioning and HLA-matched HSCT cure hemophagocytic lymphohistiocytosis.

Felber M; Steward CG; Kentouche K; Fasth A; Wynn RF; Zeilhofer U; Haunerdinger V; Volkmer B; Prader S; Gruhn B; Ehl S; Lehmberg K; Müller D; Gennery AR; Albert MH; Hauck F; Rao K; Veys P; Hassan M; Lankester AC; Schmid JP; Hauri-Hohl MM; Güngör T
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2020;143:105158

Pharmacokinetic profile of N-acetylcysteine amide and its main metabolite in mice using new analytical method.

He R; Zheng W; Ginman T; Ottosson H; Norgren S; Zhao Y; Hassan M
Article: SCIENTIFIC REPORTS. 2020;10(1):1274

A general covalent binding model between cytotoxic selenocompounds and albumin revealed by mass spectrometry and X-ray absorption spectroscopy.

Zheng W; He R; Boada R; Subirana MA; Ginman T; Ottosson H; Valiente M; Zhao Y; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2020;78:106042

The kidney injury caused by the onset of acute graft-versus-host disease is associated with down-regulation of αKlotho.

Amin R; He R; Gupta D; Zheng W; Burmakin M; Mohammad DK; DePierre JW; Sadeghi B; Olauson H; Wernerson A; El-Andaloussi S; Hassan M; Abedi-Valugerdi M
Article: FRONTIERS IN PHARMACOLOGY. 2020;11:406

Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients.

Ahmed JH; Makonnen E; Bisaso RK; Mukonzo JK; Fotoohi A; Aseffa A; Howe R; Hassan M; Aklillu E
Article: CLINICAL TRANSPLANTATION. 2019;33(12):e13742

Bone and hormonal status 10 years post-allogeneic bone marrow transplantation.

Gubrianska D; Machaczka M; Hassan M; Hägglund H; Ljungman P; Palmér M
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2019;20(19):E4734-4734

Extracellular Albumin Covalently Sequesters Selenocompounds and Determines Cytotoxicity.

Zheng W; Boada R; He R; Xiao T; Ye F; Simonelli L; Valiente M; Zhao Y; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2019;25(9):1890-1897

Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement.

McCune JS; Quinones CM; Ritchie J; Carpenter PA; van Maarseveen E; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M; Kang HJ; Kanda Y; Paci A; Perales M-A; Shaw PJ; Seewaldt VL; Savani BN; Hsieh A; Poon B; Mohty M; Pulsipher MA; Pasquini M; Dupuis LL
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2019;515(3):487-492

Degradation of pristine and oxidized single wall carbon nanotubes by CYP3A4.

El-Sayed R; Waraky A; Ezzat K; Albabtain R; ElGammal K; Shityakov S; Muhammed M; Hassan M
Article: BEHAVIOURAL BRAIN RESEARCH. 2019;367:28-34

Sustained overexpression of neuropeptide S in the amygdala reduces anxiety-like behavior in rats.

Tillmann S; Skibdal HE; Christiansen SH; Gøtzsche CR; Hassan M; Mathé AA; Wegener G; Woldbye DPD
Article: APPLIED MATERIALS TODAY. 2019;15:267-279

Tracking stem cells and macrophages with gold and iron oxide nanoparticles - The choice of the best suited particles

Sun X; Gamal M; Nold P; Said A; Chakraborty I; Pelaz B; Schmied F; von Pueckler K; Figiel J; Zhao Y; Brendel C; Hassan M; Parak WJ; Feliu N
Article: SCIENTIFIC REPORTS. 2019;9(1):3903

CT Scanning and MATLAB Calculations for Preservation of Coptic Mural Paintings in Historic Egyptian Monasteries.

Sallam A; Hemeda S; Toprak MS; Muhammed M; Hassan M; Uheida A
Article: FRONTIERS IN PHARMACOLOGY. 2019;10:481

CYP2J2∗7 Genotype Predicts Risk of Chemotherapy-Induced Hematologic Toxicity and Reduced Relative Dose Intensity in Ethiopian Breast Cancer Patients.

Ahmed JH; Makonnen E; Yimer G; Seifu D; Bekele A; Assefa M; Aseffa A; Howe R; Fotoohi A; Hassan M; Aklillu E
Article: BEHAVIOURAL BRAIN RESEARCH. 2018;351:93-103

Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression.

Sanchez C; El Khoury A; Hassan M; Wegener G; Mathé AA
Article: ASIAN PACIFIC JOURNAL OF CANCER PREVENTION. 2018;19(8):2305-2311

miR-1266-5p and miR-185-5p Promote Cell Apoptosis in Human Prostate Cancer Cell Lines.

Ostadrahimi S; Abedi Valugerdi M; Hassan M; Haddad G; Fayaz S; Parvizhamidi M; Mahdian R; Fard Esfahani P
Article: JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. 2018;46:482-489

Cold isostatic pressing of hydrating calcium sulfate as a means to produce parenteral slow-release drug formulations

Gruden S; Hassan M; Axen N
Article: SCIENTIFIC REPORTS. 2018;8(1):8293

The effect of N-acetyl-l-cysteine (NAC) on liver toxicity and clinical outcome after hematopoietic stem cell transplantation.

El-Serafi I; Remberger M; El-Serafi A; Benkessou F; Zheng W; Martell E; Ljungman P; Mattsson J; Hassan M
Article: ONCOLOGY LETTERS. 2018;15(5):8157-8164

Downregulation of miR-1266-5P, miR-185-5P and miR-30c-2 in prostatic cancer tissue and cell lines.

Ostadrahimi S; Fayaz S; Parvizhamidi M; Abedi-Valugerdi M; Hassan M; Kadivar M; Teimoori-Toolabi L; Asgari M; Shahrokh H; Abolhasani M; Mahdian R; Fard-Esfahani P
Article: JOURNAL OF THEORETICAL BIOLOGY. 2018;442:1-10

Mathematical modeling of tumor-induced immunosuppression by myeloid-derived suppressor cells: Implications for therapeutic targeting strategies.

Shariatpanahi SP; Shariatpanahi SP; Madjidzadeh K; Hassan M; Abedi-Valugerdi M
Article: NANO TODAY. 2018;18:103-123

Advances in nanotechnology for cancer biomarkers

Ye F; Zhao Y; Ei-Sayed R; Muhammed M; Hassan M
Article: JOURNAL OF CLINICAL APHERESIS. 2017;32(6):384-391

G-CSF mobilized peripheral blood stem cell collection for allogeneic transplantation in healthy donors: Analysis of factors affecting yield.

Machaczka M; Hägglund H; Staver E; Joks M; Hassan M; Wahlin BE; Axdorph Nygell U
Article: INTERNATIONAL JOURNAL OF HEMATOLOGY. 2017;106(4):471-475

Toxicological effects of fludarabine and treosulfan conditioning before allogeneic stem-cell transplantation.

Remberger M; Törlen J; Serafi IE; Garming-Legert K; Björklund A; Ljungman P; Sundin M; Hassan M; Mattsson J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;491(1):15-18

Importance of the surface chemistry of nanoparticles on peroxidase-like activity.

El-Sayed R; Ye F; Asem H; Ashour R; Zheng W; Muhammed M; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2017;52:65-71

Development of an assay for cellular efflux of pharmaceutically active agents and its relevance to understanding drug interactions.

Valdez BC; Hassan M; Andersson BS
Article: ANALYTICAL CHEMISTRY. 2017;89(14):7586-7592

Rapid and Robust Quantification of p-Xyleneselenocyanate in Plasma via Derivatization.

Zheng W; Benkessou F; Twelkmeyer B; Wang S; Ginman T; Ottosson H; Abedi-Valugerdi M; Subirana MA; Zhao Y; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2017;47:173-181

Differential effects of low-dose fludarabine or 5-fluorouracil on the tumor growth and myeloid derived immunosuppression status of tumor-bearing mice.

Abedi-Valugerdi M; Zheng W; Benkessou F; Zhao Y; Hassan M
Article: PLOS ONE. 2017;12(11):e0187294

Flavin-containing monooxygenase 3 (FMO3) role in busulphan metabolic pathway.

El-Serafi I; Terelius Y; Abedi-Valugerdi M; Naughton S; Saghafian M; Moshfegh A; Mattsson J; Potácová Z; Hassan M
Article: JOURNAL OF NANOBIOTECHNOLOGY. 2016;14(1):82

Biodistribution of biodegradable polymeric nano-carriers loaded with busulphan and designed for multimodal imaging.

Asem H; Zhao Y; Ye F; Barrefelt Å; Abedi-Valugerdi M; El-Sayed R; El-Serafi I; Abu-Salah KM; Hamm J; Muhammed M; Hassan M
Article: INTERNATIONAL IMMUNOPHARMACOLOGY. 2016;40:41-49

Suppressive effects of low-dose 5-fluorouracil, busulfan or treosulfan on the expansion of circulatory neutrophils and myeloid derived immunosuppressor cells in tumor-bearing mice.

Abedi-Valugerdi M; Wolfsberger J; Pillai PR; Zheng W; Sadeghi B; Zhao Y; Hassan M
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2016;22(11):1915-1925

Personalizing Busulfan-Based Conditioning: Considerations from the American Society for Blood and Marrow Transplantation Practice Guidelines Committee.

Palmer J; McCune JS; Perales M-A; Marks D; Bubalo J; Mohty M; Wingard JR; Paci A; Hassan M; Bredeson C; Pidala J; Shah N; Shaughnessy P; Majhail N; Schriber J; Savani BN; Carpenter PA
Article: LANCET HAEMATOLOGY. 2016;3(11):e526-e536

Association of busulfan exposure with survival and toxicity after haemopoietic cell transplantation in children and young adults: a multicentre, retrospective cohort analysis.

Bartelink IH; Lalmohamed A; van Reij EML; Dvorak CC; Savic RM; Zwaveling J; Bredius RGM; Egberts ACG; Bierings M; Kletzel M; Shaw PJ; Nath CE; Hempel G; Ansari M; Krajinovic M; Théorêt Y; Duval M; Keizer RJ; Bittencourt H; Hassan M; Güngör T; Wynn RF; Veys P; Cuvelier GDE; Marktel S; Chiesa R; Cowan MJ; Slatter MA; Stricherz MK; Jennissen C; Long-Boyle JR; Boelens JJ
Article: PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY. 2016;13:48-57

Development and biodistribution of a theranostic aluminum phthalocyanine nanophotosensitizer.

Asem H; El-Fattah AA; Nafee N; Zhao Y; Khalil L; Muhammed M; Hassan M; Kandil S
Article: PHARMACOGENOMICS JOURNAL. 2015;15(5):405-413

Cytochrome P450 2J2, a new key enzyme in cyclophosphamide bioactivation and a potential biomarker for hematological malignancies.

El-Serafi I; Fares M; Abedi-Valugerdi M; Afsharian P; Moshfegh A; Terelius Y; Potácová Z; Hassan M
Article: CELL METABOLISM. 2015;22(3):408-417

Transplanted Bone Marrow-Derived Cells Contribute to Human Adipogenesis.

Rydén M; Uzunel M; Hård JL; Borgström E; Mold JE; Arner E; Mejhert N; Andersson DP; Widlund Y; Hassan M; Jones CV; Spalding KL; Svahn B-M; Ahmadian A; Frisén J; Bernard S; Mattsson J; Arner P
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;464(3):737-742

Fluorescence labeled microbubbles for multimodal imaging.

Barrefelt Å; Zhao Y; Larsson MK; Egri G; Kuiper RV; Hamm J; Saghafian M; Caidahl K; Brismar TB; Aspelin P; Heuchel R; Muhammed M; Dähne L; Hassan M
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2015;463(3):268-274

DNA damage, lysosomal degradation and Bcl-xL deamidation in doxycycline- and minocycline-induced cell death in the K562 leukemic cell line.

Fares M; Abedi-Valugerdi M; Hassan M; Potácová Z
Article: CHEMOSPHERE. 2015;129:225-231

Complement activation is involved in the hepatic injury caused by high-dose exposure of mice to perfluorooctanoic acid.

Botelho SC; Saghafian M; Pavlova S; Hassan M; DePierre JW; Abedi-Valugerdi M
Article: CHRONOBIOLOGY INTERNATIONAL. 2015;32(5):608-614

The effect of circadian rhythm on pharmacokinetics and metabolism of the Cdk inhibitor, roscovitine, in tumor mice model.

Sallam H; El-Serafi AT; Filipski E; Terelius Y; Lévi F; Hassan M
Article: IMMUNOLOGY LETTERS. 2015;163(2):193-198

Immunotoxicological effects of streptozotocin and alloxan: in vitro and in vivo studies.

Diab RAH; Fares M; Abedi-Valugerdi M; Kumagai-Braesch M; Holgersson J; Hassan M
Article: PLOS ONE. 2015;10(11):e0141979

Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation.

El-Serafi I; Afsharian P; Moshfegh A; Hassan M; Terelius Y
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2014;58(8):4941-4943

Posaconazole concentrations in human tissues after allogeneic stem cell transplantation.

Blennow O; Eliasson E; Pettersson T; Pohanka A; Szakos A; El-Serafi I; Hassan M; Ringdén O; Mattsson J
Article: NANO. 2014;9(6):1450069

DYNAMIC MR IMAGING, BIODISTRIBUTION AND PHARMACOKINETICS OF POLYMER SHELLED MICROBUBBLES CONTAINING SPION

Barrefelt A; Paradossi G; Asem H; Margheritelli S; Saghafian M; Oddo L; Muhammed M; Aspelin P; Hassan M; Brismar TB
Article: XENOTRANSPLANTATION. 2014;21(4):353-366

Rat islets are not rejected by anti-islet antibodies in mice treated with costimulation blockade.

Diab RAH; Hassan M; Tibell A; Holgersson J; Kumagai-Braesch M
Article: LEUKEMIA & LYMPHOMA. 2014;55(7):1618-1624

The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells.

Berenjian S; Hu K; Abedi-Valugerdi M; Hassan M; Bashir Hassan S; Morein B
Article: BIOMATERIALS. 2014;35(12):3885-3894

Biodegradable polymeric vesicles containing magnetic nanoparticles, quantum dots and anticancer drugs for drug delivery and imaging.

Ye F; Barrefelt A; Asem H; Abedi-Valugerdi M; El-Serafi I; Saghafian M; Abu-Salah K; Alrokayan S; Muhammed M; Hassan M
Article: LANCET. 2014;383(9915):436-448

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study.

Güngör T; Teira P; Slatter M; Stussi G; Stepensky P; Moshous D; Vermont C; Ahmad I; Shaw PJ; Telles da Cunha JM; Schlegel PG; Hough R; Fasth A; Kentouche K; Gruhn B; Fernandes JF; Lachance S; Bredius R; Resnick IB; Belohradsky BH; Gennery A; Fischer A; Gaspar HB; Schanz U; Seger R; Rentsch K; Veys P; Haddad E; Albert MH; Hassan M; Inborn Errors Working Party of the European Societ
Article: CLINICAL DRUG INVESTIGATION. 2014;34(1):43-52

Comparison of algorithms for oral busulphan area under the concentration-time curve limited sampling estimate.

Sjöö F; El-Serafi I; Enestig J; Mattsson J; Liwing J; Hassan M
Article: THERANOSTICS. 2014;4(6):604-613

Real-time assessment of tissue hypoxia in vivo with combined photoacoustics and high-frequency ultrasound.

Gerling M; Zhao Y; Nania S; Norberg KJ; Verbeke CS; Englert B; Kuiper RV; Bergström A; Hassan M; Neesse A; Löhr JM; Heuchel RL
Article: PLOS ONE. 2014;9(1):e86619

Cyclophosphamide alters the gene expression profile in patients treated with high doses prior to stem cell transplantation.

El-Serafi I; Abedi-Valugerdi M; Potácová Z; Afsharian P; Mattsson J; Moshfegh A; Hassan M
Article: BMC PHARMACOLOGY & TOXICOLOGY. 2013;14:50

Pharmacokinetics and biodistribution of the cyclin-dependent kinase inhibitor -CR8- in mice.

Sallam H; El-Serafi I; Meijer L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2013;48(6):843-848

Omega-3 from fish oil augments GVHD through the enhancement of chemotherapy conditioning regimen and selective FoxP3 depletion.

Al Hashmi S; Sadeghi B; Hassan Z; Abedi-Valugerdi M; Lindskog M; Hassan M
Article: TOXICOLOGY LETTERS. 2013;219(1):1-7

Sub-acute, moderate-dose, but not short-term, low-dose dietary pre-exposure of mice to perfluorooctanoate aggravates concanavalin A-induced hepatitis.

Qazi MR; Hassan M; Nelson BD; Depierre JW; Abedi-Valugerdi M
Article: PEDIATRIC TRANSPLANTATION. 2013;17(3):285-293

Increased risk of gastrointestinal acute GVHD following the addition of melphalan to busulfan/cyclophosphamide conditioning.

Mårtensson T; Priftakis P; Casswall T; Ringdén O; Mattsson J; Remberger M; Hassan M; Gustafsson B
Article: NANO LETTERS. 2013;13(4):1393-1398

Thermostable luciferase from Luciola cruciate for imaging of carbon nanotubes and carbon nanotubes carrying doxorubicin using in vivo imaging system.

El-Sayed R; Eita M; Barrefelt A; Ye F; Jain H; Fares M; Lundin A; Crona M; Abu-Salah K; Muhammed M; Hassan M
Article: EJNMMI RESEARCH. 2013;3(1):12

Multimodality imaging using SPECT/CT and MRI and ligand functionalized 99mTc-labeled magnetic microbubbles.

Barrefelt AA; Brismar TB; Egri G; Aspelin P; Olsson A; Oddo L; Margheritelli S; Caidahl K; Paradossi G; Dähne L; Axelsson R; Hassan M
Article: TOXICOLOGY LETTERS. 2013;217(1):67-74

Both sub-acute, moderate-dose and short-term, low-dose dietary exposure of mice to perfluorooctane sulfonate exacerbates concanavalin A-induced hepatitis.

Qazi MR; Hassan M; Nelson BD; DePierre JW; Abedi-Valugerdi M
Article: BONE MARROW TRANSPLANTATION. 2013;48(2):284-293

Early-phase GVHD gene expression profile in target versus non-target tissues: kidney, a possible target?

Sadeghi B; Al-Chaqmaqchi H; Al-Hashmi S; Brodin D; Hassan Z; Abedi-Valugerdi M; Moshfegh A; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2013;913-914:98-105

Gas chromatographic-mass spectrometry method for the detection of busulphan and its metabolites in plasma and urine.

El-Serafi I; Terelius Y; Twelkmeyer B; Hagbjörk A-L; Hassan Z; Hassan M
Article: PLOS ONE. 2013;8(4):e60367

The role of programmed cell death ligand-1 (PD-L1/CD274) in the development of graft versus host disease.

Al-Chaqmaqchi H; Sadeghi B; Abedi-Valugerdi M; Al-Hashmi S; Fares M; Kuiper R; Lundahl J; Hassan M; Moshfegh A
Article: INTERNATIONAL JOURNAL OF NANOMEDICINE. 2013;8:3241-3254

Biodistribution, kinetics, and biological fate of SPION microbubbles in the rat.

Barrefelt Å; Saghafian M; Kuiper R; Ye F; Egri G; Klickermann M; Brismar TB; Aspelin P; Muhammed M; Dähne L; Hassan M
Article: PLOS ONE. 2013;8(7):e68937

Activation of Wnt/β-catenin pathway in monocytes derived from chronic kidney disease patients.

Al-Chaqmaqchi HAM; Moshfegh A; Dadfar E; Paulsson J; Hassan M; Jacobson SH; Lundahl J
Article: PLOS ONE. 2012;7(1):e30897

Busulphan-cyclophosphamide cause endothelial injury, remodeling of resistance arteries and enhanced expression of endothelial nitric oxide synthase.

Al-Hashmi S; Boels PJM; Zadjali F; Sadeghi B; Sällström J; Hultenby K; Hassan Z; Arner A; Hassan M
Article: NATURE MEDICINE. 2011;17(12):1636-1640

Inhibition of proteasome deubiquitinating activity as a new cancer therapy.

D'Arcy P; Brnjic S; Olofsson MH; Fryknäs M; Lindsten K; De Cesare M; Perego P; Sadeghi B; Hassan M; Larsson R; Linder S
Article: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(11):1688-1697

Improved survival after allogeneic hematopoietic stem cell transplantation in recent years. A single-center study.

Remberger M; Ackefors M; Berglund S; Blennow O; Dahllöf G; Dlugosz A; Garming-Legert K; Gertow J; Gustafsson B; Hassan M; Hassan Z; Hauzenberger D; Hägglund H; Karlsson H; Klingspor L; Kumlien G; Le Blanc K; Ljungman P; Machaczka M; Malmberg K-J; Marschall H-U; Mattsson J; Olsson R; Omazic B; Sairafi D; Schaffer M; Svahn B-M; Svenberg P; Swartling L; Szakos A; Uhlin M; Uzunel M; Watz E; Wernerson A; Wikman A; Wikström A-C; Winiarski J; Ringdén O
Article: ORAL DISEASES. 2011;17(7):670-676

Long-term salivary function after conditioning with busulfan, fractionated or single-dose TBI.

Garming-Legert K; Remberger M; Ringdén O; Hassan M; Dahllöf G
Article: PEDIATRIC TRANSPLANTATION. 2011;15(6):580-588

Therapeutic drug monitoring is essential for intravenous busulfan therapy in pediatric hematopoietic stem cell recipients.

Malär R; Sjöö F; Rentsch K; Hassan M; Güngör T
Article: INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY. 2011;4(6):596-605

Dynamics of early histopathological changes in GVHD after busulphan/cyclophosphamide conditioning regimen.

Al-Hashmi S; Hassan Z; Sadeghi B; Rozell B; Hassan M
Article: SULTAN QABOOS UNIVERSITY MEDICAL JOURNAL. 2011;11(2):165-178

The Role of Pharmacokinetics and Pharmacodynamics in Early Drug Development with reference to the Cyclin-dependent Kinase (Cdk) Inhibitor - Roscovitine.

Hassan M; Sallam H; Hassan Z
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2011;41(4):1143-1153

N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro.

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringdén O
Article: CLINICAL AND DEVELOPMENTAL IMMUNOLOGY. 2010;2010:142943-13

Expansion and activation kinetics of immune cells during early phase of GVHD in mouse model based on chemotherapy conditioning.

Sadeghi B; Al-Hashmi S; Hassan Z; Rozell B; Concha H; Lundmark C; Grönvik K-O; Abedi-Valugerdi M; Hassan M
Article: CHRONOBIOLOGY INTERNATIONAL. 2009;26(8):1613-1621

Circadian variability of bilirubin in healthy men during normal sleep and after an acute shift of sleep.

Larsson A; Hassan M; Ridefelt P; Axelsson J
Article: CHRONOBIOLOGY INTERNATIONAL. 2009;26(6):1169-1188

Liver circadian clock, a pharmacologic target of cyclin-dependent kinase inhibitor seliciclib.

Iurisci I; Filipski E; Sallam H; Harper F; Guettier C; Maire I; Hassan M; Iacobelli S; Lévi F
Article: BONE MARROW TRANSPLANTATION. 2008;42(12):807-818

GVHD after chemotherapy conditioning in allogeneic transplanted mice.

Sadeghi B; Aghdami N; Hassan Z; Forouzanfar M; Rozell B; Abedi-Valugerdi M; Hassan M
Article: MOLECULAR CANCER THERAPEUTICS. 2008;7(9):2713-2724

N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine.

Bettayeb K; Sallam H; Ferandin Y; Popowycz F; Fournet G; Hassan M; Echalier A; Bernard P; Endicott J; Joseph B; Meijer L
Article: TRANSPLANTATION. 2008;86(2):257-263

Evaluation of immune responses to seasonal influenza vaccination in healthy volunteers and in patients after stem cell transplantation.

Avetisyan G; Aschan J; Hassan M; Ljungman P
Article: PHARMACOLOGICAL RESEARCH. 2008;58(1):32-37

Age-dependent pharmacokinetics and effect of roscovitine on Cdk5 and Erk1/2 in the rat brain.

Sallam H; Jimenez P; Song H; Vita M; Cedazo-Minguez A; Hassan M
Article: NATURE. 2008;453(7196):783-787

Dynamics of fat cell turnover in humans.

Spalding KL; Arner E; Westermark PO; Bernard S; Buchholz BA; Bergmann O; Blomqvist L; Hoffstedt J; Näslund E; Britton T; Concha H; Hassan M; Rydén M; Frisén J; Arner P
Article: BONE MARROW TRANSPLANTATION. 2008;41(10):895-904

The effect of administration order of BU and CY on engraftment and toxicity in HSCT mouse model.

Sadeghi B; Jansson M; Hassan Z; Mints M; Hägglund H; Abedi-Valugerdi M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2008;41(9):785-790

A prospective randomized study using N-acetyl-L-cysteine for early liver toxicity after allogeneic hematopoietic stem cell transplantation.

Barkholt L; Remberger M; Hassan Z; Fransson K; Omazic B; Svahn B-M; Karlsson H; Brune M; Hassan M; Mattsson J; Ringdén O
Article: BONE MARROW TRANSPLANTATION. 2008;41(7):621-625

Safe administration of oral BU twice daily during conditioning for stem cell transplantation in a paediatric population: a comparative study between the standard 4-dose and a 2-dose regimen.

Mellgren K; Nilsson C; Fasth A; Abrahamsson J; Winiarski J; Ringdén O; Hassan M
Article: JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. 2008;31(5):683-694

Rapid and sensitive method for determination of cyclophosphamide in patients plasma samples utilizing microextraction by packed sorbent online with liquid chromatography-tandem mass spectrometry (MEPS-LC-MS/MS)

Said R; Hassan Z; Hassan M; Abdel-Rehim M
Article: EXPERIMENTAL HEMATOLOGY. 2008;36(2):149-157

Hypomethylation and apoptosis in 5-azacytidine-treated myeloid cells.

Khan R; Schmidt-Mende J; Karimi M; Gogvadze V; Hassan M; Ekström TJ; Zhivotovsky B; Hellström-Lindberg E
Article: HUMAN REPRODUCTION. 2008;23(1):139-143

Endometrial endothelial cells are derived from donor stem cells in a bone marrow transplant recipient.

Mints M; Jansson M; Sadeghi B; Westgren M; Uzunel M; Hassan M; Palmblad J
Article: THERAPEUTIC DRUG MONITORING. 2007;29(5):626-631

Higher plasma but not intracellular concentrations after infusion with liposomal daunorubicin compared with conventional daunorubicin in adult acute myeloid leukemia.

Löfgren C; Lehmann S; Jönsson-Videsäter K; Möllgård L; Linder O; Tidefelt U; Hassan M; Paul C
Article: JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES. 2007;30(20):3029-3041

Simultaneous determination of busulphan in plasma samples by liquid chromatography-electrospray ionization mass spectrometry utilizing microextraction in packed syringe (MEPS) as on-line sample preparation method

Abdel-Rehim M; Hassan Z; Skansem P; Hassan M
Article: CLINICAL CANCER RESEARCH. 2007;13(14):4218-4224

The effect of repeated administration of cyclophosphamide on cytochrome P450 2B in rats.

Afsharian P; Terelius Y; Hassan Z; Nilsson C; Lundgren S; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2006;38(10):687-692

Impact on the cytomegalovirus (CMV) viral load by CMV-specific T-cell immunity in recipients of allogeneic stem cell transplantation.

Avetisyan G; Larsson K; Aschan J; Nilsson C; Hassan M; Ljungman P
Article: NATURE MEDICINE. 2006;12(4):401-409

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

Ott MG; Schmidt M; Schwarzwaelder K; Stein S; Siler U; Koehl U; Glimm H; Kühlcke K; Schilz A; Kunkel H; Naundorf S; Brinkmann A; Deichmann A; Fischer M; Ball C; Pilz I; Dunbar C; Du Y; Jenkins NA; Copeland NG; Lüthi U; Hassan M; Thrasher AJ; Hoelzer D; von Kalle C; Seger R; Grez M
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2006;98(2):197-200

Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients.

Gunes A; Coskun U; Boruban C; Gunel N; Babaoglu MO; Sencan O; Bozkurt A; Rane A; Hassan M; Zengil H; Yasar U
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):115-121

Myeloablative and immunosuppressive properties of treosulfan in mice.

Sjöö F; Hassan Z; Abedi-Valugerdi M; Griskevicius L; Nilsson C; Remberger M; Aschan J; Concha H; Gaughan U; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2006;34(1):35-43

A pharmacodynamic study of 5-azacytidine in the P39 cell line.

Khan R; Aggerholm A; Hokland P; Hassan M; Hellström-Lindberg E
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2006;27(1):54-61

Pharmacogenetics of cyclophosphamide in patients with hematological malignancies.

Xie H; Griskevicius L; Ståhle L; Hassan Z; Yasar U; Rane A; Broberg U; Kimby E; Hassan M
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2005;75(3):206-211

The effect of ciprofloxacin on cyclophosphamide pharmacokinetics in patients with non-Hodgkin lymphoma.

Afsharian P; Möllgård L; Hassan Z; Xie H; Kimby E; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2005;36(5):411-415

Cell-mediated immune responses to influenza vaccination in healthy volunteers and allogeneic stem cell transplant recipients.

Avetisyan G; Ragnavölgyi E; Toth GT; Hassan M; Ljungman P
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;821(1):75-80

Stability, pKa and plasma protein binding of roscovitine.

Vita M; Abdel-Rehim M; Nilsson C; Hassan Z; Skansen P; Wan H; Meurling L; Hassan M
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2005;141(2):238-247

Bacterial lipopolysaccharide both renders resistant mice susceptible to mercury-induced autoimmunity and exacerbates such autoimmunity in susceptible mice.

Abedi-Valugerdi M; Nilsson C; Zargari A; Gharibdoost F; DePierre JW; Hassan M
Article: TRANSPLANTATION. 2005;79(11):1607-1614

Fetal mesenchymal stem-cell engraftment in bone after in utero transplantation in a patient with severe osteogenesis imperfecta.

Le Blanc K; Götherström C; Ringdén O; Hassan M; McMahon R; Horwitz E; Anneren G; Axelsson O; Nunn J; Ewald U; Nordén-Lindeberg S; Jansson M; Dalton A; Aström E; Westgren M
Article: EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES. 2005;25(1):91-103

Tissue distribution, pharmacokinetics and identification of roscovitine metabolites in rat.

Vita M; Abdel-Rehim M; Olofsson S; Hassan Z; Meurling L; Sidén A; Sidén M; Pettersson T; Hassan M
Article: ANALYTICA CHIMICA ACTA. 2005;539(1-2):35-39

Microextraction in packed syringe/liquid chromatography/electrospray tandem mass spectrometry for quantification of olomoucine in human plasma samples

Abdel-Rehim M; Skansen P; Vita M; Hassan Z; Blomberg L; Hassan M
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 2005;817(2):303-307

Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on-line sample preparation.

Vita M; Skansen P; Hassan M; Abdel-Rehim M
Article: XENOBIOTICA. 2005;35(3):239-251

Cyclophosphamide induces mRNA, protein and enzyme activity of cytochrome P450 in rat.

Xie H; Afsharian P; Terelius Y; Mirghani RA; Yasar U; Hagbjörk A-L; Lundgren S; Hu Y; Rane A; Hassan M
Article: EXPERIMENTAL HEMATOLOGY. 2005;33(3):380-387

Effect of altering administration order of busulphan and cyclophosphamide on the myeloablative and immunosuppressive properties of the conditioning regimen in mice.

Nilsson C; Forsman J; Hassan Z; Abedi-Valugerdi M; O'Connor C; Concha H; Jansson M; Hassan M
Article: IMMUNOLOGY. 2005;114(3):428-437

Exposure to mercuric chloride during the induction phase and after the onset of collagen-induced arthritis enhances immune/autoimmune responses and exacerbates the disease in DBA/1 mice.

Hansson M; Djerbi M; Rabbani H; Mellstedt H; Gharibdoost F; Hassan M; Depierre JW; Abedi-Valugerdi M
Article: TRANSPLANTATION. 2004;78(1):154-157

Lung epithelial cells and type II pneumocytes of donor origin after allogeneic hematopoietic stem cell transplantation.

Mattsson J; Jansson M; Wernerson A; Hassan M
Article: LANCET. 2004;363(9419):1439-1441

Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells.

Le Blanc K; Rasmusson I; Sundberg B; Götherström C; Hassan M; Uzunel M; Ringdén O
Article: JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS. 2004;34(2):425-431

Analysis of roscovitine using novel high performance liquid chromatography and UV-detection method: pharmacokinetics of roscovitine in rat.

Vita M; Meurling L; Pettersson T; Cruz-Sidén M; Sidén A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(5):477-483

Fractionated TBI correlates with less T cell mixed chimerism but increased risk of relapse compared to busulphan in patients with haematological malignancies after allogeneic stem cell transplantation.

Mattsson J; Uzunel M; Remberger M; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;32(4):349-354

N-acetyl-L-cysteine does not affect the pharmacokinetics or myelosuppressive effect of busulfan during conditioning prior to allogeneic stem cell transplantation.

Sjöö F; Aschan J; Barkholt L; Hassan Z; Ringdén O; Hassan M
Article: CLINICAL CANCER RESEARCH. 2003;9(7):2447-2456

Immunization of colorectal carcinoma patients with a recombinant canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colony- stimulating factor induced a tumor-specific cellular immune response.

Ullenhag GJ; Frödin J-E; Mosolits S; Kiaii S; Hassan M; Bonnet MC; Moingeon P; Mellstedt H; Rabbani H
Article: THERAPEUTIC DRUG MONITORING. 2003;25(3):400-406

On-line derivatization utilizing solid-phase microextraction (SPME) for determination of busulphan in plasma using gas chromatography-mass spectrometry (GC-MS).

Abdel-Rehim M; Hassan Z; Blomberg L; Hassan M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2003;59(2):103-109

Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes.

Griskevicius L; Yasar U; Sandberg M; Hidestrand M; Eliasson E; Tybring G; Hassan M; Dahl M-L
Article: BONE MARROW TRANSPLANTATION. 2003;31(6):429-435

The effect of metronidazole on busulfan pharmacokinetics in patients undergoing hematopoietic stem cell transplantation.

Nilsson C; Aschan J; Hentschke P; Ringdén O; Ljungman P; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2003;31(3):197-203

Alteration of pharmacokinetics of cyclophosphamide and suppression of the cytochrome p450 genes by ciprofloxacin.

Xie H-J; Broberg U; Griskevicius L; Lundgren S; Carlens S; Meurling L; Paul C; Rane A; Hassan M
Article: PHARMACOGENOMICS JOURNAL. 2003;3(1):53-61

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation.

Xie H-J; Yasar U; Lundgren S; Griskevicius L; Terelius Y; Hassan M; Rane A
Article: BONE MARROW TRANSPLANTATION. 2002;30(12):833-841

A phase II trial of liposomal busulphan as an intravenous myeloablative agent prior to stem cell transplantation: 500 mg/m(2) as a optimal total dose for conditioning.

Hassan M; Nilsson C; Hassan Z; Gungor T; Aschan J; Winiarski J; Hentschke P; Ringdén O; Eber S; Seger R; Ljungman P
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2002;449(3):197-205

Effect of cyclophosphamide on gene expression of cytochromes p450 and beta-actin in the HL-60 cell line.

Xie H-J; Lundgren S; Broberg U; Finnström N; Rane A; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2002;30(3):141-147

The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo.

Hassan Z; Hellström-Lindberg E; Alsadi S; Edgren M; Hägglund H; Hassan M
Article: THERAPEUTIC DRUG MONITORING. 2002;24(3):405-409

Simple method based on fluorescent detection for the determination of 4-hydroxycyclophosphamide in plasma.

Griskevicius L; Meurling L; Hassan M
Article: BRITISH JOURNAL OF CANCER. 2001;85(12):2004-2009

Bioavailability and dose-dependent anti-tumour effects of 9-cis retinoic acid on human neuroblastoma xenografts in rat.

Ponthan F; Kogner P; Bjellerup P; Klevenvall L; Hassan M
Article: BONE MARROW TRANSPLANTATION. 2001;28(7):657-664

Population pharmacokinetic analysis resulting in a tool for dose individualization of busulphan in bone marrow transplantation recipients.

Sandström M; Karlsson MO; Ljungman P; Hassan Z; Jonsson EN; Nilsson C; Ringden O; Oberg G; Bekassy A; Hassan M
Article: LEUKEMIA. 2001;15(8):1240-1247

The pharmacodynamic effect of busulfan in the P39 myeloid cell line in vitro.

Hassan Z; Hassan M; Hellström-Lindberg E
Article: CLINICAL CANCER RESEARCH. 2001;7(5):1163-1170

Alteration of interleukin 2 (IL-2) pharmacokinetics and function by IL-2 antibodies induced after treatment of colorectal carcinoma patients with a combination of monoclonal antibody 17-1A, granulocyte macrophage colony-stimulating factor, and IL-2.

Hjelm Skog AL; Wadhwa M; Hassan M; Gharizadeh B; Bird C; Ragnhammar P; Thorpe R; Mellstedt H
Article: BONE MARROW TRANSPLANTATION. 2001;27(5):479-485

Pharmacokinetics of liposomal busulphan in man.

Hassan Z; Ljungman P; Ringdén O; Winiarski J; Nilsson C; Aschan J; Whitley HR; Hassan M
Article: JOURNAL OF LIPID RESEARCH. 2001;42(1):70-78

Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study.

Meaney S; Hassan M; Sakinis A; Lütjohann D; von Bergmann K; Wennmalm A; Diczfalusy U; Björkhem I
Article: LEUKEMIA. 2000;14(11):1954-1959

A phase I/II study of multiple-dose intravenous busulfan as myeloablation prior to stem cell transplantation.

Olavarria E; Hassan M; Eades A; Nilsson C; Timms A; Matthews J; Craddock C; Kanfer E; Apperley J; Goldman J
Article: THERAPEUTIC DRUG MONITORING. 2000;22(4):383-385

Ketobemidone may alter busulfan pharmacokinetics during high-dose therapy.

Hassan M; Svensson JO; Nilsson C; Hentschke P; Al-Shurbaji A; Aschan J; Ljungman P; Ringdén O
Article: BONE MARROW TRANSPLANTATION. 2000;25(9):915-924

The effect of busulphan on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite: time interval influence on therapeutic efficacy and therapy-related toxicity.

Hassan M; Ljungman P; Ringdén O; Hassan Z; Oberg G; Nilsson C; Békassy A; Bielenstein M; Abdel-Rehim M; Georén S; Astner L
Article: JOURNAL OF SEPARATION SCIENCE. 2000;23(2):156-157

Capillary gas chromatography of trichlorophenols using ammonia as carrier gas

Abdel-Rehim M; Hassan M
Article: NUCLEAR MEDICINE AND BIOLOGY. 1999;26(8):931-936

Biodistribution of liposomal 131I-VIP in rat using gamma camera.

Refai E; Jonsson C; Andersson M; Jacobsson H; Larsson S; Kogner P; Hassan M
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 1999;48(5):669-677

A mechanism-based pharmacokinetic-enzyme model for cyclophosphamide autoinduction in breast cancer patients.

Hassan M; Svensson US; Ljungman P; Björkstrand B; Olsson H; Bielenstein M; Abdel-Rehim M; Nilsson C; Johansson M; Karlsson MO
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 1999;63(3):163-170

The influence of interferon-alpha on the pharmacokinetics of cyclophosphamide and its 4-hydroxy metabolite in patients with multiple myeloma.

Hassan M; Nilsson C; Olsson H; Lundin J; Osterborg A
Article: NUCLEAR MEDICINE AND BIOLOGY. 1999;26(4):413-420

In vivo dynamic distribution of 131I-glucagon-like peptide-1 (7-36) amide in the rat studied by gamma camera.

Hassan M; Eskilsson A; Nilsson C; Jonsson C; Jacobsson H; Refai E; Larsson S; Efendic S
Article: LIFE SCIENCES. 1999;65(2):165-174

In vivo evaluation of the biodistribution of 11C-labeled PD153035 in rats without and with neuroblastoma implants.

Fredriksson A; Johnström P; Thorell JO; von Heijne G; Hassan M; Eksborg S; Kogner P; Borgström P; Ingvar M; Stone-Elander S
Article: BONE MARROW TRANSPLANTATION. 1998;22(9):913-918

Liposomal busulphan: bioavailability and effect on bone marrow in mice.

Hassan Z; Nilsson C; Hassan M
Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 1998;42(6):471-478

Pharmacokinetics and distribution of liposomal busulfan in the rat: a new formulation for intravenous administration.

Hassan M; Hassan Z; Nilsson C; Rehim MA; Kumlien S; Elfsson B; Kållberg N
Article: BONE MARROW TRANSPLANTATION. 1997;20(11):909-913

High busulfan concentrations are associated with increased transplant-related mortality in allogeneic bone marrow transplant patients.

Ljungman P; Hassan M; Békássy AN; Ringdén O; Oberg G
Article: BONE MARROW TRANSPLANTATION. 1996;18(5):843-850

Busulphan kinetics and limited sampling model in children with leukemia and inherited disorders.

Hassan M; Fasth A; Gerritsen B; Haraldsson A; Syrůcková Z; van den Berg H; Sandström M; Karlsson M; Kumlien S; Vossen J
Article: PEDIATRIC HEMATOLOGY AND ONCOLOGY. 1996;13(2):143-150

Infection-associated hemophagocytic syndrome complicated by infectious lymphoproliferation: a case report.

Syrůcková Z; Starý J; Sedlácek P; Smísek P; Vavrinec J; Komrska V; Roubalová K; Vandasová J; Sintáková B; Housková J; Hassan M
Article: JOURNAL OF SEPARATION SCIENCE. 1996;8(2):151-156

Enantiomer separation of underivatized tocainide and related compounds by CGC using ammonia as carrier gas

AbdelRehim M; Karlen A; Zhang L; Kamel M; Hassan M
Article: JOURNAL OF SEPARATION SCIENCE. 1995;18(12):757-759

Effect of ammonia on the response of the electron capture detector (ECD)

AbdelRehim M; Kamel M; Hassan M
Article: EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS. 1995;20(3):225-232

Kinetics and metabolism of 2-chloro-2'-deoxyadenosine and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine in the isolated perfused rat liver.

Albertioni F; Hassan M; Silberring J; Liliemark J
Article: BONE MARROW TRANSPLANTATION. 1995;15(6):869-871

Busulfan concentration in relation to permanent alopecia in recipients of bone marrow transplants.

Ljungman P; Hassan M; Békássy AN; Ringdén O; Oberg G
Article: INTERNATIONAL PSYCHOGERIATRICS. 1995;7(1):75-83

One year on tacrine (THA): clinical and biochemical effects in patients with dementia of the Alzheimer type.

Ahlin A; Junthé T; Hassan M; Nybäck H
Visa fler

Alla övriga publikationer

Editorial comment: CELL JOURNAL. 2023;25(10):738-740

A Shadow of Knowledge in Stem Cell Science.

Omid-Shafiee S; Hassan M; Nussler AK; Mustapha N; Vosough M
Review: CELLS. 2023;12(18):2260

Circulating Tumor Cells as a Promising Tool for Early Detection of Hepatocellular Carcinoma.

Salehi M; Lavasani ZM; Keshavarz Alikhani H; Shokouhian B; Hassan M; Najimi M; Vosough M
Review: CELL JOURNAL. 2023;25(5):281-290

Platelet-Rich Plasma in Regenerative Medicine: Possible Applications in Management of Burns and Post-Burn Scars: A Review.

Hosseini MS; Nouri M; Zarrabi M; Fatemi MJ; Shpichka A; Timashev P; Hassan M; Vosough M
Review: BIOMEDICINE & PHARMACOTHERAPY. 2023;161:114487

Autophagy orchestrates resistance in hepatocellular carcinoma cells.

Seydi H; Nouri K; Rezaei N; Tamimi A; Hassan M; Mirzaei H; Vosough M
Review: BIOMEDICAL MATERIALS. 2023;18(3):032001

Progress and promise of cell sheet assisted cardiac tissue engineering in regenerative medicine.

Abdolahzadeh H; Rad NK; Shpichka A; Golroo R; Rahi K; Timashev P; Hassan M; Vosough M
Review: EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. 2023;17(3):237-249

Cell and cell-derivative-based therapy for liver diseases: current approaches and future promises.

Zahmatkesh E; Khoshdel Rad N; Hossein-Khannazer N; Mohamadnejad M; Gramignoli R; Najimi M; Malekzadeh R; Hassan M; Vosough M
Review: JOURNAL OF CELLULAR PHYSIOLOGY. 2022;237(11):3984-4000

Hepatogenesis and hepatocarcinogenesis: Alignment of the main signaling pathways.

Shokouhian B; Aboulkheyr Es H; Negahdari B; Tamimi A; Shahdoust M; Shpichka A; Timashev P; Hassan M; Vosough M
Review: JOURNAL OF PERSONALIZED MEDICINE. 2022;12(11):1797

Cardiovascular Complications in Hematopoietic Stem Cell Transplanted Patients.

Zhao Y; He R; Oerther S; Zhou W; Vosough M; Hassan M
Review: MOLECULAR BIOLOGY REPORTS. 2022;49(2):1545-1549

Mini review ATF4 and GRP78 as novel molecular targets in ER-Stress modulation for critical COVID-19 patients.

Shahriari-Felordi M; Alikhani HK; Hashemian S-MR; Hassan M; Vosough M
Editorial comment: EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. 2022;16(1):1-3

COVID-19 and hygiene hypothesis: increment of the inflammatory bowel diseases in next generation?

Shahrbaf MA; Hassan M; Vosough M
Review: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:894800

Regulatory Non-Coding RNAs in Familial Hypercholesterolemia, Theranostic Applications.

Keshavarz Alikhani H; Pourhamzeh M; Seydi H; Shokoohian B; Hossein-Khannazer N; Jamshidi-Adegani F; Al-Hashmi S; Hassan M; Vosough M
Review: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2021;25(18):8602-8614

Advanced therapeutic modalities in hepatocellular carcinoma: Novel insights.

Shokoohian B; Negahdari B; Aboulkheyr Es H; Abedi-Valugerdi M; Baghaei K; Agarwal T; Maiti TK; Hassan M; Najimi M; Vosough M
Review: PHARMACOLOGY & THERAPEUTICS. 2021;220:107714

Novel molecular targets in gastric adenocarcinoma.

Ramezankhani R; Solhi R; Es HA; Vosough M; Hassan M
Review: ACS NANO. 2021;15(3):3754-3807

X-ray-Based Techniques to Study the Nano-Bio Interface.

Sanchez-Cano C; Alvarez-Puebla RA; Abendroth JM; Beck T; Blick R; Cao Y; Caruso F; Chakraborty I; Chapman HN; Chen C; Cohen BE; Conceição ALC; Cormode DP; Cui D; Dawson KA; Falkenberg G; Fan C; Feliu N; Gao M; Gargioni E; Glüer C-C; Grüner F; Hassan M; Hu Y; Huang Y; Huber S; Huse N; Kang Y; Khademhosseini A; Keller TF; Körnig C; Kotov NA; Koziej D; Liang X-J; Liu B; Liu S; Liu Y; Liu Z; Liz-Marzán LM; Ma X; Machicote A; Maison W; Mancuso AP; Megahed S; Nickel B; Otto F; Palencia C; Pascarelli S; Pearson A; Peñate-Medina O; Qi B; Rädler J; Richardson JJ; Rosenhahn A; Rothkamm K; Rübhausen M; Sanyal MK; Schaak RE; Schlemmer H-P; Schmidt M; Schmutzler O; Schotten T; Schulz F; Sood AK; Spiers KM; Staufer T; Stemer DM; Stierle A; Sun X; Tsakanova G; Weiss PS; Weller H; Westermeier F; Xu M; Yan H; Zeng Y; Zhao Y; Zhao Y; Zhu D; Zhu Y; Parak WJ
Review: FRONTIERS IN MICROBIOLOGY. 2021;12:785856

Application of Stem Cell-Derived Extracellular Vesicles as an Innovative Theranostics in Microbial Diseases.

Keshavarz Alikhani H; Shokoohian B; Rezasoltani S; Hossein-Khannazer N; Yadegar A; Hassan M; Vosough M
Editorial comment: TRANSPLANTATION AND CELLULAR THERAPY. 2020;26(9):e235-e236

Response to Kawedia et al Letter to Editor in Response to the Article by McCune Et Al "Harmonization of Busulfan Plasma Exposure Unit (BPEU): A Community-Initiated Consensus Statement".

Dupuis LL; Quinones CM; Ritchie J; Carpenter PA; Bauters T; Yeh RF; Anasetti C; Boelens JJ; Hamerschlak N; Hassan M; Kang HJ; Kanda Y; Paci A; Perales M-A; Shaw PJ; Seewaldt VL; Savani BN; Militano O; Pulsipher MA; McCune JS
Editorial comment: FRONTIERS IN NEUROANATOMY. 2016;10:14

Commentary: Impact of a deletion of the full-length and short isoform of p75NTR on cholinergic innervation and the population of postmitotic doublecortin positive cells in the dentate gyrus.

Sabry MA; Fares M; Folkesson R; Al-Ramadan M; Alabkal J; Al-Kafaji G; Hassan M
Editorial comment: HAEMATOLOGICA. 2014;99(7):1124-1127

Hematologic malignancies in elderly patients.

Hassan M; Abedi-Valugerdi M
Review: PHARMACOGENOMICS. 2013;14(1):75-87

Role of pharmacogenetics in busulfan/cyclophosphamide conditioning therapy prior to hematopoietic stem cell transplantation.

Hassan M; Andersson BS
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2011;17(2):S345

DYNAMICS OF DONOR T CELL ACTIVATION DURING EARLY PHASE OF GRAFT VERSUS HOST DISEASE (GVHD): DONOR ANTIGEN PRESENTING CELLS CAN ACTIVATE ALLOGENEIC T CELLS

Sadeghi B; Al-Hashmi S; Hassan Z; Hassan M
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2009;15(2):127

N-ACETYL-L-CYSTEINE PROMOTES T CELL MEDIATED IMMUNITY IN ALLOGENEIC SETTINGS IN VIVO AND IN VITRO

Karlsson H; Nava S; Remberger M; Hassan Z; Hassan M; Ringden O
Meeting abstract: LEUKEMIA RESEARCH. 2007;31:S62-S63

Hypomethylation and apoptosis in 5-azacytidine treated myeloid cells

Khan R; Schmidt-Mende J; Karimi M; Forsblom A-M; Gogvadze V; Hassan M; Ekstrom TJ; Zhivotovsky B; Hellstrom-Lindberg E
Meeting abstract: TRANSPLANTATION AND CELLULAR THERAPY. 2007;13(2):70-71

The role of human CYP2B6 polymorphism in the bioactivation of cyclophosphamide using CDNA expressed enzymes

Afsharian P; Teredius Y; Hidestrand M; Ingelman-Sundberg M; Hassan M; Lundgren S
Meeting abstract: BLOOD. 2006;108(11):97A

Effect of busulphan dose adjustment on regimen-related toxicity.

Hassan Z; Remberger M; Ringden O; Oberg G; Bekassy AN; Hassan M
Meeting abstract: BLOOD. 2005;106(11):193B

The effect of repeated administration of cyclophosphamide on CYP2B1 and 2B2 in rat.

Afsharian P; Terelius Y; Lundgren S; Hassan M
Meeting abstract: BLOOD. 2005;106(11):60A

Long-term follow-up of patients treated by gene therapy for X-linked chronic granulomatous disease.

Ott MG; Grez M; Stein S; Siler U; Koehl U; Kuehlcke K; Schmidt M; Schilz A; Kunkel H; Naundorf S; Brinkmann A; Hassan M; von Kalle C; Trasher A; Seger R; Hoelzer D
Published conference paper: PEDIATRIC BLOOD & CANCER. 2001;36(1):127-131

The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo.

Ponthan F; Borgström P; Hassan M; Wassberg E; Redfern CP; Kogner P
Review: MEDICAL ONCOLOGY. 1999;16(3):166-176

The role of busulfan in bone marrow transplantation.

Hassan M
Published conference paper: PEDIATRIC RESEARCH. 1999;46(3):328-332

The somatostatin analogue octreotide inhibits neuroblastoma growth in vivo.

Borgström P; Hassan M; Wassberg E; Refai E; Jonsson C; Larsson SA; Jacobsson H; Kogner P
Published conference paper: EUROPEAN JOURNAL OF CANCER. 1997;33(12):2084-2089

Somatostatin in neuroblastoma and ganglioneuroma.

Kogner P; Borgström P; Bjellerup P; Schilling FH; Refai E; Jonsson C; Dominici C; Wassberg E; Bihl H; Jacobsson H; Theodorsson E; Hassan M
Review: LEUKEMIA & LYMPHOMA. 1996;22(5-6):395-&

Aspects concerning busulfan pharmacokinetics and bioavailability.

Hassan M; Ehrsson H; Ljungman P
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