Forskningsbeskrivning
SubCellBarCode: Proteome-wide Mapping of Protein Localization and Relocalization. Orre LM, Vesterlund M, Pan Y, Arslan T, Zhu Y, Fernandez Woodbridge A, et al Mol. Cell 2019 01;73(1):166-182.e7
See also: SubCellBarCode
Proteomics identifies neddylation as a potential therapy target in small intestinal neuroendocrine tumors. Fotouhi O, Kjellin H, Juhlin CC, Pan Y, Vesterlund M, Ghaderi M, et al Oncogene 2019 Oct;38(43):6881-6897
Breast cancer quantitative proteome and proteogenomic landscape. Johansson HJ, Socciarelli F, Vacanti NM, Haugen MH, Zhu Y, Siavelis I, et al Nat Commun 2019 04;10(1):1600
Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia. Yang M, Vesterlund M, Siavelis I, Moura-Castro LH, Castor A, Fioretos T, et al Nat Commun 2019 04;10(1):1519
Novel Multiomics Profiling of Human Carotid Atherosclerotic Plaques and Plasma Reveals Biliverdin Reductase B as a Marker of Intraplaque Hemorrhage. Matic LP, Jesus Iglesias M, Vesterlund M, Lengquist M, Hong MG, Saieed S, et al JACC Basic Transl Sci 2018 Aug;3(4):464-480
Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow. Zhu Y, Orre LM, Johansson HJ, Huss M, Boekel J, Vesterlund M, et al Nat Commun 2018 03;9(1):903
Metabolic reprogramming of acute lymphoblastic leukemia cells in response to glucocorticoid treatment. Dyczynski M, Vesterlund M, Björklund AC, Zachariadis V, Janssen J, Gallart-Ayala H, et al Cell Death Dis 2018 08;9(9):846
Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications. Nassa G, Giurato G, Cimmino G, Rizzo F, Ravo M, Salvati A, et al Sci Rep 2018 01;8(1):498
An antisense RNA capable of modulating the expression of the tumor suppressor microRNA-34a. Serviss JT, Andrews N, Van den Eynden J, Richter FC, Houtman M, Vesterlund M, et al Cell Death Dis 2018 07;9(7):736
Regulation of PfEMP1-VAR2CSA translation by a Plasmodium translation-enhancing factor. Chan S, Frasch A, Mandava CS, Ch'ng JH, Quintana MDP, Vesterlund M, et al Nat Microbiol 2017 May;2():17068
Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling. Anderson JD, Johansson HJ, Graham CS, Vesterlund M, Pham MT, Bramlett CS, et al Stem Cells 2016 Mar;34(3):601-13
Phenotypic Modulation of Smooth Muscle Cells in Atherosclerosis Is Associated With Downregulation of LMOD1, SYNPO2, PDLIM7, PLN, and SYNM. Perisic Matic L, Rykaczewska U, Razuvaev A, Sabater-Lleal M, Lengquist M, Miller CL, et al Arterioscler. Thromb. Vasc. Biol. 2016 09;36(9):1947-61
Androgen-independent effects of Serenoa repens extract (Prostasan®) on prostatic epithelial cell proliferation and inflammation. Iglesias-Gato D, Carsten T, Vesterlund M, Pousette A, Schoop R, Norstedt G Phytother Res 2012 Feb;26(2):259-64
Cell type and context-specific function of PLAG1 for IGF2 P3 promoter activity. Akhtar M, Holmgren C, Göndör A, Vesterlund M, Kanduri C, Larsson C, et al Int. J. Oncol. 2012 Dec;41(6):1959-66
SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice. Zadjali F, Santana-Farre R, Vesterlund M, Carow B, Mirecki-Garrido M, Hernandez-Hernandez I, et al FASEB J. 2012 Aug;26(8):3282-91
Sex-dependent hepatic transcripts and metabolites in the development of glucose intolerance and insulin resistance in Zucker diabetic fatty rats. Gustavsson C, Soga T, Wahlström E, Vesterlund M, Azimi A, Norstedt G, et al J. Mol. Endocrinol. 2011 Oct;47(2):129-43
Structural basis for c-KIT inhibition by the suppressor of cytokine signaling 6 (SOCS6) ubiquitin ligase. Zadjali F, Pike AC, Vesterlund M, Sun J, Wu C, Li SS, et al J. Biol. Chem. 2011 Jan;286(1):480-90
The SOCS2 ubiquitin ligase complex regulates growth hormone receptor levels. Vesterlund M, Zadjali F, Persson T, Nielsen ML, Kessler BM, Norstedt G, et al PLoS ONE 2011 ;6(9):e25358