Maria Needhamsen

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: MULTIPLE SCLEROSIS AND RELATED DISORDERS. 2023;79:104991

Smoking affects epigenetic ageing of lung bronchoalveolar lavage cells in Multiple Sclerosis.

Klose D; Needhamsen M; Ringh MV; Hagemann-Jensen M; Jagodic M; Kular L
Article: LEUKEMIA. 2023;37(9):1830-1841

Perturbed epigenetic transcriptional regulation in AML with IDH mutations causes increased susceptibility to NK cells.

Palau A; Segerberg F; Lidschreiber M; Lidschreiber K; Naughton AJ; Needhamsen M; Jung LA; Jagodic M; Cramer P; Lehmann S; Carlsten M; Lennartsson A
Journal article: FRONTIERS IN IMMUNOLOGY. 2023;14:1251772

Simultaneous detection of DNA variation and methylation at HLA class II locus and immune gene promoters using targeted SureSelect Methyl-Sequencing.

Kalomoiri M; Prakash CR; Lagström S; Hauschulz K; Ewing E; Shchetynsky K; Kular L; Needhamsen M; Jagodic M
Article: EPIGENETICS. 2022;17(11):1311-1330

DNA methylation changes in glial cells of the normal-appearing white matter in Multiple Sclerosis patients.

Kular L; Ewing E; Needhamsen M; Pahlevan Kakhki M; Covacu R; Gomez-Cabrero D; Brundin L; Jagodic M
Article: EPIGENETICS. 2022;17(10):1195-1204

Comparison of EM-seq and PBAT methylome library methods for low-input DNA.

Han Y; Zheleznyakova GY; Marincevic-Zuniga Y; Kakhki MP; Raine A; Needhamsen M; Jagodic M
Article: FRONTIERS IN AGING NEUROSCIENCE. 2022;14:926468

Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients.

Kular L; Klose D; Urdánoz-Casado A; Ewing E; Planell N; Gomez-Cabrero D; Needhamsen M; Jagodic M
Article: FRONTIERS IN GENETICS. 2022;13:1042483

Integration of small RNAs from plasma and cerebrospinal fluid for classification of multiple sclerosis.

Needhamsen M; Khoonsari PE; Zheleznyakova GY; Piket E; Hagemann-Jensen M; Han Y; Gierlich J; Ekman D; Jagodic M
Article: NATURE COMMUNICATIONS. 2021;12(1):6061

TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis.

Tulstrup M; Soerensen M; Hansen JW; Gillberg L; Needhamsen M; Kaastrup K; Helin K; Christensen K; Weischenfeldt J; Grønbæk K
Article: MULTIPLE SCLEROSIS JOURNAL. 2021;27(7):1014-1026

Methylome and transcriptome signature of bronchoalveolar cells from multiple sclerosis patients in relation to smoking.

Ringh MV; Hagemann-Jensen M; Needhamsen M; Kullberg S; Wahlström J; Grunewald J; Brynedal B; Jagodic M; Ekström TJ; Öckinger J; Kular L
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(17):e2011574118

Small noncoding RNA profiling across cellular and biofluid compartments and their implications for multiple sclerosis immunopathology.

Zheleznyakova GY; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Han Y; James T; Khademi M; Al Nimer F; Scicluna P; Huang J; Kockum I; Faridani OR; Olsson T; Piehl F; Jagodic M
Article: EBIOMEDICINE. 2019;46:290-304

Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells.

Ringh MV; Hagemann-Jensen M; Needhamsen M; Kular L; Breeze CE; Sjöholm LK; Slavec L; Kullberg S; Wahlström J; Grunewald J; Brynedal B; Liu Y; Almgren M; Jagodic M; Öckinger J; Ekström TJ
Article: CLINICAL EPIGENETICS. 2019;11(1):86

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis.

Kular L; Needhamsen M; Adzemovic MZ; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegnér J; Beck S; Piehl F; Brundin L; Jagodic M
Article: NATURE COMMUNICATIONS. 2018;9(1):4845

Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells.

Lund H; Pieber M; Parsa R; Han J; Grommisch D; Ewing E; Kular L; Needhamsen M; Espinosa A; Nilsson E; Överby AK; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: NATURE IMMUNOLOGY. 2018;19(5):1-7

Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.

Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Kular L; Han J; Zhu K; Nijssen J; Hedlund E; Needhamsen M; Ruhrmann S; Guerreiro-Cacais AO; Berglund R; Forteza MJ; Ketelhuth DFJ; Butovsky O; Jagodic M; Zhang X-M; Harris RA
Article: BMC BIOINFORMATICS. 2017;18(1):486

Usability of human Infinium MethylationEPIC BeadChip for mouse DNA methylation studies.

Needhamsen M; Ewing E; Lund H; Gomez-Cabrero D; Harris RA; Kular L; Jagodic M
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2016;101(6):2450-2459

Contribution of Heritability and Epigenetic Factors to Skeletal Muscle Mass Variation in United Kingdom Twins.

Livshits G; Gao F; Malkin I; Needhamsen M; Xia Y; Yuan W; Bell CG; Ward K; Liu Y; Wang J; Bell JT; Spector TD
Article: EVOLUTIONARY BIOINFORMATICS. 2014;10:107-113

Regulation of Human PAX6 Expression by miR-7.

Needhamsen M; White RB; Giles KM; Dunlop SA; Thomas MG
Article: DNA AND CELL BIOLOGY. 2010;29(10):589-601

Localization and differential expression of the Krüppel-associated box zinc finger proteins 1 and 54 in early mouse development.

Albertsen M; Teperek M; Elholm G; Füchtbauer E-M; Lykke-Hartmann K

Alla övriga publikationer

Conference publication: NEUROLOGY. 2023;100(17)

Genetic Variants in Iron Metabolism impact Disease Progression in MS through HIF1A

Giordano A; Santoro S; Sorosina M; Mascia E; Clarelli F; Cannizzaro M; Ferre L; Moridi T; Stridh P; Shchetynsky K; Needhamsen M; Piehl F; Alfredsson L; Hillert J; Olsson T; Kockum I; Jagodic M; Filippi M; Esposito F
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):183-184

Profiling of small non-coding rnas across cellular and biofluid compartments in patients with multiple sclerosis

Zheleznyakova G; Piket E; Needhamsen M; Hagemann-Jensen M; Ekman D; Khademi M; Al Nimer F; Scicluna P; Faridani O; Olsson T; Piehl F; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2020;26(3_SUPPL):572

Dna methylation of cerebrospinal fluid cells in multiple sclerosis

Zheleznyakova G; Han Y; Ivanova E; Khademi M; Piehl F; Olsson T; Kelsey G; Needhamsen M; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:212-213

DNA methylation changes in brains from multiple sclerosis patients

Kular L; Needhamsen M; Zeitelhofer-Adzemovic M; Kramarova T; Gomez-Cabrero D; Ewing E; Piket E; Tegner J; Beck S; Piehl F; Brundin L; Jagodic M
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2019;25:726

Genome-wide small-noncoding RNA analysis in patients with multiple sclerosis

Zheleznyakova G; Piket E; Needhamsen M; Hagemann-Jensen M; Faridani O; Marabita F; Khademi M; Piehl F; Olsson T; Jagodic M
Review: PHYSIOLOGICAL GENOMICS. 2017;49(9):447-461

Epigenetic research in multiple sclerosis: progress, challenges, and opportunities.

Zheleznyakova GY; Piket E; Marabita F; Pahlevan Kakhki M; Ewing E; Ruhrmann S; Needhamsen M; Jagodic M; Kular L
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):297

TGF-beta defines microglia and monocyte function in the central nervous system

Lund H; Pieber M; Parsa R; Grommisch D; Ewing E; Needhamsen M; Ruhrmann S; Kular L; Ortlieb A; Cacais G; Butovsky O; Jagodic M; Zhang X; Harris RA
Conference publication: MULTIPLE SCLEROSIS JOURNAL. 2016;22:485-486

Analysis of DNA methylation in post-mortem brain tissue from Multiple Sclerosis patients

Needhamsen M; Kular L; Kramarova T; Gomez-Cabrero D; Ewing E; Adzemovic MZ; Tegner J; Brundin L; Jagodic M

Anställningar

Senior Forskningsinfrastrukturspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2024-
Forskningsspecialist, Klinisk neurovetenskap, Karolinska Institutet, 2022-2023

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