Marlin Johansson
Anknuten till Forskning
E-postadress: marlin.johansson@ki.se
Besöksadress: Hälsovägen, Enheten för öron-,näs och halssjukdomar B61, 14186 Stockholm
Postadress: H9 Klinisk vetenskap, intervention och teknik, H9 CLINTEC Öron näs o halssjukd, 171 77 Stockholm
Om mig
- I am a PhD student in medicine, audiology, at the ENT-division at CLINTEC,
Stockholm, with a background in clinical audiology. I have a special interest
in pediatrics and unilateral sensorineural hearing loss, hearing aids and
other intervention options, newborn hearing-screening, neuroplasticity and
inner ear mechanics.
Forskningsbeskrivning
- The overall aim of my PhD project is to study the causes and mechanisms
underlying congenital unilateral sensorineural hearing loss (uSNHL) and the
effects of intervention.
In the first PhD publication (Ear & - Hearing, 2020) we studied hearing aid
outcomes in school-aged children with congenital uNSHL and demonstrate both
hearing aid benefit and dis-benefit. The statistically significant benefit
was found in one-to-one communication, based on child and parent
questionnaires. Hearing aid dis-benefit was found for sound localization
measured with eye-tracking in sound field. Neither significant hearing aid
benefit nor dis-benefit existed for speech understanding in background
noise/speech (sound field and questionnaires) or reverberation
(questionnaires). A close relationship between neural maturation and aided
sound localization was also found, indicating that hearing aids may be more
efficient if fitted earlier in development, before the brain adapts to
asymmetrical hearing.
In the second PhD publication (Hearing Research, 2020) we studied heredity of
transient evoked otoacoustic emissions (TEOAEs), that are recorded as part of
the universal neonatal hearing-screening program. Before the study, one
publication had estimated TEOAE heritability based on young adult twins’
TEOAEs. In a large consecutive sample of neonatal twins (n = 454), we found
that the TEOAEs at birth are largely inherited, perhaps more than for young
adult twins. Additionally, we found that sex and ear differences existed at
birth, and that the twin testosterone transfer hypothesis, that female twins
with male co-twins would have masculinized TEOAEs, was not supported for
neonatal twins.
In my third PhD publication (Journal of Clinical Medicine, 2022) we study the
etiologic background for congenital uSNHL and describe the auditory profiles
of twenty consecutively recruited infants from the neonatal hearing-screening
program in Region Stockholm. We present MRI, CMV and ABR results in the
publication, and are currently also evaluating the twenty infant's genetic
profiles and their auditory and speech-language development and hearing aid
benefit longitudinally over the 2.5 first years of life.
Artiklar
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Article: JOURNAL OF CLINICAL MEDICINE. 2023;12(2):495
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Article: JOURNAL OF CLINICAL MEDICINE. 2022;11(14):3966
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Article: HEARING RESEARCH. 2020;398:108108
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Article: EAR AND HEARING. 2020;41(1):55-66
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Article: JOURNAL OF PEDIATRICS. 2014;164(2):352-357
Alla övriga publikationer
Anställningar
- Anknuten till Forskning, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2023-2025
Examina och utbildning
- Medicine Doktorsexamen, Institutionen för klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2023