Maria Kippler

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Docent i miljömedicin vid Karolinska Institutet, Institutet för
Miljömedicin, Enheten för Metaller och Hälsa.
PhD i Medicinsk Vetenskap, Karolinska Institutet, 2009.
MSc i Toxicologi, Karolinska Institutet, 2004.

Forskningsbeskrivning

Den övergripnade målsättningen med forskningen som utförs i min
forskningsgrupp att öka kunskapen om hur exponering för miljöföreningar,
framför allt metaller, tidigit i livet kan påverka barns hälsa
och utveckling. Vi studerar även betydelsen av essentiella spårelement och
andra näringsämnen (t.ex. selen och jod) och om det förekommer
interaktioner mellan dessa och olika toxiska metaller. Detta uppnås genom
att kombinera epidemiologiska och mekanistiska studier i material från olika
mor-barn kohorter. Metaller och andra spårelement mätts framför allt med
induktivt kopplad plasmamasspektrometri (ICP-MS), vilket möjliggör analys
ett flertal element i låga doser på mycket kort tid. Effektbiomarkörer
mätts med flera olika metoder.

Artiklar

Article: EXPOSURE AND HEALTH. 2024;16(2):357-368

Mediation by Thyroid Hormone in the Relationships Between Gestational Exposure to Methylmercury and Birth Size

Gustin K; Ekvall KO; Barman M; Jacobsson B; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
Article: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE. 2024;35(25):9014-9022

Maternal characteristics and pregnancy outcomes in the NICE birth cohort: an assessment of self-selection bias.

Ögge LE; Murray F; Modzelewska D; Lundqvist R; Nilsson S; Carré H; Kippler M; Wold AE; Sandberg A-S; Sandin A; Jacobsson B; Barman M
Article: ENVIRONMENTAL RESEARCH. 2024;248:118355

Toxic metals and essential trace elements in placenta and their relation to placental function.

Grundeken M; Gustin K; Vahter M; Delaval M; Barman M; Sandin A; Sandberg A-S; Wold AE; Broberg K; Kippler M
Article: REDOX BIOCHEM CHEM. 2023;5-6:100015

Arsenic exposure and increased C-reactive protein are independently associated with lower erythrocyte glutathione peroxidase activity in Bangladeshi children.

Cheff DM; Skröder H; Akhtar E; Cheng Q; Hall MD; Raqib R; Kippler M; Vahter M; Arnér ESJ
Article: MOVEMENT DISORDERS. 2023;38(12):2302-2307

Prediagnostic Blood Metal Levels and the Risk of Parkinson's Disease: A Large European Prospective Cohort.

Zhao Y; Ray A; Broberg K; Kippler M; Lill CM; Vineis P; Katzke VA; Rodriguez-Barranco M; Chirlaque M-D; Guevara M; Gómez J-H; Hansen J; Panico S; Middleton LT; Masala G; Pala V; Vinagre-Aragon A; Zibetti M; Vermeulen R; Peters S
Article: JOURNAL OF INTERNAL MEDICINE. 2023;294(3):358-369

Urinary phosphate is associated with cardiovascular disease incidence.

Donat-Vargas C; Guallar-Castillon P; Nyström J; Larsson SC; Kippler M; Vahter M; Faxén-Irving G; Michaelsson K; Wolk A; Stenvinkel P; Åkesson A
Article: ENVIRONMENT INTERNATIONAL. 2023;178:108071

Associations of gestational and early-life exposure to toxic metals and fluoride with a diagnosis of food allergy or atopic eczema at 1 year of age.

Kampouri M; Gustin K; Stråvik M; Barman M; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
Article: ENVIRONMENTAL RESEARCH. 2023;227:115787

Polycyclic aromatic hydrocarbon (PAH) exposure during pregnancy and child anthropometry from birth to 10 years of age: Sex-specific evidence from a cohort study in rural Bangladesh.

Rahman SM; Malin Igra A; Essig JY; Ekström E-C; Dreij K; Trask M; Lindh C; Arifeen SE; Rahman A; Krais AM; Kippler M
Article: ENVIRONMENTAL RESEARCH. 2023;225:115576

Biomarkers of seafood intake during pregnancy - Pollutants versus fatty acids and micronutrients.

Stråvik M; Gustin K; Barman M; Levi M; Sandin A; Wold AE; Sandberg A-S; Kippler M; Vahter M
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2023;52(1):144-155

Gestational and childhood urinary iodine concentrations and children's cognitive function in a longitudinal mother-child cohort in rural Bangladesh.

Kampouri M; Tofail F; Rahman SM; Gustin K; Vahter M; Kippler M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2023;131(2):27003

Early Life Environmental Exposure to Cadmium, Lead, and Arsenic and Age at Menarche: A Longitudinal Mother-Child Cohort Study in Bangladesh.

Malin Igra A; Rahman A; Johansson ALV; Pervin J; Svefors P; Arifeen SE; Vahter M; Persson L-Å; Kippler M
Article: FRONTIERS IN NUTRITION. 2023;10:1058965

Dietary patterns and indicators of cardiometabolic risk among rural adolescents: A cross-sectional study at 15-year follow-up of the MINIMat cohort.

Islam MR; Rahman SM; Selling K; Näsänen-Gilmore P; Kippler M; Kajantie E; Rahman A; Pervin J; Ekström E-C
Article: ENVIRONMENTAL RESEARCH. 2022;214(Pt 4):114129

Association of maternal urinary fluoride concentrations during pregnancy with size at birth and the potential mediation effect by maternal thyroid hormones: The Swedish NICE birth cohort.

Kampouri M; Gustin K; Stråvik M; Barman M; Levi M; Daraki V; Jacobsson B; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
Journal article: ISEE CONFERENCE ABSTRACTS. 2022;2022(1)

Association of maternal fluoride exposure during pregnancy with increased size at birth and the potential mediation effect by maternal thyroid hormones: the Swedish NICE birth cohort

Kampouri M; Gustin K; Stråvik M; Barman M; Levi M; Daraki V; Jacobsson B; Sandin A; Sandberg A-S; Wold A; Vahter M; Kippler M
Article: JOURNAL OF NUTRITION. 2022;152(7):1737-1746

Assessment of Joint Impact of Iodine, Selenium, and Zinc Status on Women's Third-Trimester Plasma Thyroid Hormone Concentrations.

Gustin K; Vahter M; Barman M; Jacobsson B; Skröder H; Filipsson Nyström H; Sandin A; Sandberg A-S; Wold AE; Kippler M
Article: ENVIRONMENT INTERNATIONAL. 2022;163:107188

Maternal exposure to cadmium during pregnancy is associated with changes in DNA methylation that are persistent at 9 years of age.

Gliga AR; Malin Igra A; Hellberg A; Engström K; Raqib R; Rahman A; Vahter M; Kippler M; Broberg K
Article: ENVIRONMENT INTERNATIONAL. 2022;161:107114

Long-term cadmium exposure and fractures, cardiovascular disease, and mortality in a prospective cohort of women.

Tägt J; Helte E; Donat-Vargas C; Larsson SC; Michaëlsson K; Wolk A; Vahter M; Kippler M; Åkesson A
Article: ENVIRONMENT INTERNATIONAL. 2021;157:106869

Thyroid hormones in relation to toxic metal exposure in pregnancy, and potential interactions with iodine and selenium.

Gustin K; Barman M; Skröder H; Jacobsson B; Sandin A; Sandberg A-S; Wold AE; Vahter M; Kippler M
Article: ENVIRONMENTAL POLLUTION. 2021;289:117905

Associations of exposure to cadmium, antimony, lead and their mixture with gestational thyroid homeostasis.

Margetaki K; Vafeiadi M; Kampouri M; Roumeliotaki T; Karakosta P; Daraki V; Kogevinas M; Hu H; Kippler M; Chatzi L
Article: ENVIRONMENT INTERNATIONAL. 2021;156:106738

Environmental metal exposure and growth to 10 years of age in a longitudinal mother-child cohort in rural Bangladesh.

Malin Igra A; Warnqvist A; Rahman SM; Ekström E-C; Rahman A; Vahter M; Kippler M
Article: ENVIRONMENT INTERNATIONAL. 2021;154:106562

A cohort study of the association between prenatal arsenic exposure and age at menarche in a rural area, Bangladesh.

Rahman A; Kippler M; Pervin J; Tarafder C; Lucy IJ; Svefors P; Arifeen SE; Persson LÅ
Journal article: ISEE CONFERENCE ABSTRACTS. 2021;2021(1)

Prenatal Metal Mixtures and Child Blood Pressure in the Rhea Mother-Child Cohort

Howe CG; Margetaki K; Vafeiadi M; Roumeliotaki T; Karachaliou M; Kogevinas M; McConnell R; Eckel SP; Conti DV; Kippler M; Farzan SF; Chatzi L
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2021;129(4):47005

Fluoride in Drinking Water, Diet, and Urine in Relation to Bone Mineral Density and Fracture Incidence in Postmenopausal Women.

Helte E; Donat Vargas C; Kippler M; Wolk A; Michaëlsson K; Åkesson A
Article: ENVIRONMENTAL POLLUTION. 2021;271:116333

A longitudinal study of rural Bangladeshi children with long-term arsenic and cadmium exposures and biomarkers of cardiometabolic diseases.

Akhtar E; Roy AK; Haq MA; von Ehrenstein OS; Ahmed S; Vahter M; Ekstrom E-C; Kippler M; Wagatsuma Y; Raqib R
Article: ENVIRONMENTAL HEALTH. 2021;20(1):1

Prenatal metal mixtures and child blood pressure in the Rhea mother-child cohort in Greece.

Howe CG; Margetaki K; Vafeiadi M; Roumeliotaki T; Karachaliou M; Kogevinas M; McConnell R; Eckel SP; Conti DV; Kippler M; Farzan SF; Chatzi L
Article: FRONTIERS IN NUTRITION. 2021;8:733602

Infant Iodine and Selenium Status in Relation to Maternal Status and Diet During Pregnancy and Lactation.

Stråvik M; Gustin K; Barman M; Skröder H; Sandin A; Wold AE; Sandberg A-S; Kippler M; Vahter M
Article: ENVIRONMENTAL POLLUTION. 2021;268(Pt A):115712

Total mercury in hair as biomarker for methylmercury exposure among women in central Sweden- a 23 year long temporal trend study.

Kippler M; Gyllenhammar I; Glynn A; Levi M; Lignell S; Berglund M
Article: ANNALS OF NEUROLOGY. 2021;89(1):125-133

Blood Metal Levels and Amyotrophic Lateral Sclerosis Risk: A Prospective Cohort.

Peters S; Broberg K; Gallo V; Levi M; Kippler M; Vineis P; Veldink J; van den Berg L; Middleton L; Travis RC; Bergmann MM; Palli D; Grioni S; Tumino R; Elbaz A; Vlaar T; Mancini F; Kühn T; Katzke V; Agudo A; Goñi F; Gómez J-H; Rodríguez-Barranco M; Merino S; Barricarte A; Trichopoulou A; Jenab M; Weiderpass E; Vermeulen R
Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)

Low-level maternal exposure to cadmium, lead, and methylmercury and birth outcomes in a Swedish prospective birth-cohort

Gustin K; Barman M; Stråvik M; Levi M; Englund-Ögge L; Murray F; Jacobsson B; Sandberg A; Sandin A; Wold AE; Vahter M; Kippler M
Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)

Association of childhood multiple essential and toxic trace elements with longitudinal cardiometabolic risk factors

Margetaki K; Stratakis N; Vafeiadi M; Roumeliotaki T; Vahter M; Kogevinas M; Kippler M; Chatzi L
Journal article: ISEE CONFERENCE ABSTRACTS. 2020;2020(1)

Fluoride in diet, drinking water and urine in relation to bone mineral density and incidence of fractures

Helte E; Donat Vargas C; Kippler M; Wolk A; Michaëlsson K; Åkesson A
Article: ENVIRONMENTAL POLLUTION. 2020;265(Pt B):114986

Low-level maternal exposure to cadmium, lead, and mercury and birth outcomes in a Swedish prospective birth-cohort.

Gustin K; Barman M; Stråvik M; Levi M; Englund-Ögge L; Murray F; Jacobsson B; Sandberg A-S; Sandin A; Wold AE; Vahter M; Kippler M
Article: ENVIRONMENT INTERNATIONAL. 2020;139:105723

Prenatal and childhood arsenic exposure through drinking water and food and cognitive abilities at 10 years of age: A prospective cohort study.

Vahter M; Skröder H; Rahman SM; Levi M; Derakhshani Hamadani J; Kippler M
Article: NANOMATERIALS. 2020;10(4):E618-618

Dry Generation of CeO2 Nanoparticles and Deposition onto a Co-Culture of A549 and THP-1 Cells in Air-Liquid Interface-Dosimetry Considerations and Comparison to Submerged Exposure.

Cappellini F; Di Bucchianico S; Karri V; Latvala S; Malmlöf M; Kippler M; Elihn K; Hedberg J; Odnevall Wallinder I; Gerde P; Karlsson HL
Journal article: ENVIRONMENTAL EPIDEMIOLOGY. 2019;3:260

Association between prenatal exposure to multiple metals and maternal and child thyroid hormone levels

K M; M V; T R; P K; V D; G C; M V; M K; M K; L C
Article: ENVIRONMENT INTERNATIONAL. 2019;126:1-6

Dietary exposure to polychlorinated biphenyls and risk of heart failure - A population-based prospective cohort study.

Åkesson A; Donat-Vargas C; Berglund M; Glynn A; Wolk A; Kippler M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2019;127(3):37003

Early-Life Cadmium Exposure and Bone-Related Biomarkers: A Longitudinal Study in Children.

Malin Igra A; Vahter M; Raqib R; Kippler M
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2019;188(1):141-150

Associations of Prenatal Exposure to Cadmium With Child Growth, Obesity, and Cardiometabolic Traits.

Chatzi L; Ierodiakonou D; Margetaki K; Vafeiadi M; Chalkiadaki G; Roumeliotaki T; Fthenou E; Pentheroudaki E; McConnell R; Kogevinas M; Kippler M
Article: ENVIRONMENT INTERNATIONAL. 2018;121(Pt 1):842-851

Predictors of selenium biomarker kinetics in 4-9-year-old Bangladeshi children.

Skröder H; Kippler M; De Loma J; Raqib R; Vahter M
Article: BMJ OPEN. 2018;8(10):e022013

Nutritional impact on Immunological maturation during Childhood in relation to the Environment (NICE): a prospective birth cohort in northern Sweden.

Barman M; Murray F; Bernardi AI; Broberg K; Bölte S; Hesselmar B; Jacobsson B; Jonsson K; Kippler M; Rabe H; Ross AB; Sjöberg F; Strömberg N; Vahter M; Wold AE; Sandberg A-S; Sandin A
Article: TOXICOLOGICAL SCIENCES. 2018;164(2):539-549

Associations of Arsenic Exposure With Telomere Length and Naïve T Cells in Childhood-A Birth Cohort Study.

Mannan T; Ahmed S; Akhtar E; Ahsan KB; Haq A; Kippler M; Vahter M; Raqib R
Article: ARCHIVES OF TOXICOLOGY. 2018;92(8):2487-2500

Prenatal arsenic exposure is associated with increased plasma IGFBP3 concentrations in 9-year-old children partly via changes in DNA methylation.

Gliga AR; Engström K; Kippler M; Skröder H; Ahmed S; Vahter M; Raqib R; Broberg K
Article: ENVIRONMENT INTERNATIONAL. 2018;113:259-268

Cadmium exposure and cognitive abilities and behavior at 10 years of age: A prospective cohort study.

Gustin K; Tofail F; Vahter M; Kippler M
Journal article: CIRCULATION. 2018;137(suppl_1)

Abstract P104: Dietary Polychlorinated biphenyls and Long-chain Omega-3 Fish fatty acids Exposures and Risk of Heart Failure

Kippler M; Donat Vargas C; Berglund M; Glynn A; Wolk A; Åkesson A
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2018;126(2):027001

Associations between Methylated Metabolites of Arsenic and Selenium in Urine of Pregnant Bangladeshi Women and Interactions between the Main Genes Involved.

Skröder H; Engström K; Kuehnelt D; Kippler M; Francesconi K; Nermell B; Tofail F; Broberg K; Vahter M
Journal article: ISEE CONFERENCE ABSTRACTS. 2018;2017(1)

Hair as Biomarker of Toxic and Essential Trace Elements in Children

Skröder H; Kippler M; Nermell B; Tofail F; Levi M; Rahman SM; Raqib R; Vahter M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(11):117003

Early-Life Selenium Status and Cognitive Function at 5 and 10 Years of Age in Bangladeshi Children.

Skröder H; Kippler M; Tofail F; Vahter M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067021

Major Limitations in Using Element Concentrations in Hair as Biomarkers of Exposure to Toxic and Essential Trace Elements in Children.

Skröder H; Kippler M; Nermell B; Tofail F; Levi M; Rahman SM; Raqib R; Vahter M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(6):067006

Humoral Immunity in Arsenic-Exposed Children in Rural Bangladesh: Total Immunoglobulins and Vaccine-Specific Antibodies.

Raqib R; Ahmed S; Ahsan KB; Kippler M; Akhtar E; Roy AK; Lu Y; Arifeen SE; Wagatsuma Y; Vahter M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2017;125(5):057003

Manganese in Drinking Water and Cognitive Abilities and Behavior at 10 Years of Age: A Prospective Cohort Study.

Rahman SM; Kippler M; Tofail F; Bölte S; Hamadani JD; Vahter M
Article: ENVIRONMENT INTERNATIONAL. 2017;102:97-105

Methylmercury exposure and cognitive abilities and behavior at 10years of age.

Gustin K; Tofail F; Mehrin F; Levi M; Vahter M; Kippler M
Article: EUROPEAN JOURNAL OF EPIDEMIOLOGY. 2016;31(11):1123-1134

Impact of prenatal exposure to cadmium on cognitive development at preschool age and the importance of selenium and iodine.

Kippler M; Bottai M; Georgiou V; Koutra K; Chalkiadaki G; Kampouri M; Kyriklaki A; Vafeiadi M; Fthenou E; Vassilaki M; Kogevinas M; Vahter M; Chatzi L
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2016;104(5):1318-1326

Effects of wheat-flour biscuits fortified with iron and EDTA, alone and in combination, on blood lead concentration, iron status, and cognition in children: a double-blind randomized controlled trial.

Bouhouch RR; El-Fadeli S; Andersson M; Aboussad A; Chabaa L; Zeder C; Kippler M; Baumgartner J; Sedki A; Zimmermann MB
Article: ENVIRONMENTAL RESEARCH. 2016;151:628-634

Prenatal lead exposure and childhood blood pressure and kidney function.

Skröder H; Hawkesworth S; Moore SE; Wagatsuma Y; Kippler M; Vahter M
Article: BRITISH JOURNAL OF CANCER. 2016;115(9):1113-1121

Dietary exposure to polychlorinated biphenyls and risk of breast, endometrial and ovarian cancer in a prospective cohort.

Donat-Vargas C; Åkesson A; Berglund M; Glynn A; Wolk A; Kippler M
Article: ENVIRONMENT INTERNATIONAL. 2016;94:706-711

Associations of dietary polychlorinated biphenyls and long-chain omega-3 fatty acids with stroke risk.

Kippler M; Larsson SC; Berglund M; Glynn A; Wolk A; Åkesson A
Journal article: REPRODUCTIVE TOXICOLOGY. 2016;64:16

Prenatal metal exposure and effects on the placenta: DNA methylation as a putative mechanism of action

Broberg K; Kippler M
Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)

Prenatal exposure to metals and essential trace elements and the risk of childhood obesity: a prospective pregnancy cohort study

Chatzi* L; Kippler M; Vafeiadi M; Pentheroudaki E; Roumeliotaki T; Chalkiadaki G; Fthenou E; Sarri K; Vassilaki M; Kogevinas M; Vahter M
Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)

Early-life selenium status and cognitive function in childhood

Löveborn* HS; Kippler M; Tofail F; Vahter M
Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)

Prenatal cadmium exposure and effects on fetal growth: placental DNA methylation as a putative mechanism of action.

Vilahur* N; Malin* A; Ruiz C; Harari F; Runze L; Amaya E; Bustamante M; Kippler M; Fernandez MF; Olea N; Sunyer J; Broberg K
Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)

Dietary exposure to polychlorinated biphenyls and risk of cancers of the breast, endometrium and ovary: A Prospective Cohort Study

Donat-Vargas* C; Åkesson A; Berglund M; Glynn A; Wolk A; Kippler M
Journal article: ISEE CONFERENCE ABSTRACTS. 2016;2016(1)

Counteracting associations of dietary polychlorinated biphenyls and omega-3 fatty acids with stroke risk

Åkesson* A; Kippler M; Larsson S; Berglund M; Glynn A; Wolk A
Article: CELL BIOLOGY AND TOXICOLOGY. 2016;32(4):275-284

Arsenic alters global histone modifications in lymphocytes in vitro and in vivo.

Pournara A; Kippler M; Holmlund T; Ceder R; Grafström R; Vahter M; Broberg K; Wallberg AE
Article: TOXICOLOGICAL SCIENCES. 2016;152(1):29-39

Arsenic Metabolism in Children Differs From That in Adults.

Skröder Löveborn H; Kippler M; Lu Y; Ahmed S; Kuehnelt D; Raqib R; Vahter M
Article: TOXICOLOGICAL SCIENCES. 2016;149(2):473-483

Common Polymorphisms in the Solute Carrier SLC30A10 are Associated With Blood Manganese and Neurological Function.

Wahlberg K; Kippler M; Alhamdow A; Rahman SM; Smith DR; Vahter M; Lucchini RG; Broberg K
Article: ENVIRONMENT INTERNATIONAL. 2016;86:119-125

Elevated childhood exposure to arsenic despite reduced drinking water concentrations--A longitudinal cohort study in rural Bangladesh.

Kippler M; Skröder H; Rahman SM; Tofail F; Vahter M
Article: PLOS ONE. 2016;11(8):e0161294

Maternal Micronutrient Supplementation and Long Term Health Impact in Children in Rural Bangladesh.

Mannan T; Ahmed S; Akhtar E; Roy AK; Haq MA; Roy A; Kippler M; Ekström E-C; Wagatsuma Y; Raqib R
Article: AMERICAN JOURNAL OF CLINICAL NUTRITION. 2015;102(6):1406-1415

Selenium metabolism to the trimethylselenonium ion (TMSe) varies markedly because of polymorphisms in the indolethylamine N-methyltransferase gene.

Kuehnelt D; Engström K; Skröder H; Kokarnig S; Schlebusch C; Kippler M; Alhamdow A; Nermell B; Francesconi K; Broberg K; Vahter M
Article: CLINICAL NUTRITION. 2015;34(5):923-930

Selenium status in pregnancy influences children's cognitive function at 1.5 years of age.

Skröder HM; Hamadani JD; Tofail F; Persson LÅ; Vahter ME; Kippler MJ
Article: ENVIRONMENTAL RESEARCH. 2015;140:205-213

Kidney function and blood pressure in preschool-aged children exposed to cadmium and arsenic--potential alleviation by selenium.

Skröder H; Hawkesworth S; Kippler M; El Arifeen S; Wagatsuma Y; Moore SE; Vahter M
Article: REPRODUCTIVE TOXICOLOGY. 2015;53:68-74

Manganese exposure through drinking water during pregnancy and size at birth: A prospective cohort study.

Rahman SM; Kippler M; Ahmed S; Palm B; El Arifeen S; Vahter M
Article: CLINICAL BIOCHEMISTRY. 2015;48(3):140-147

Alkali dilution of blood samples for high throughput ICP-MS analysis-comparison with acid digestion.

Lu Y; Kippler M; Harari F; Grandér M; Palm B; Nordqvist H; Vahter M
Article: ENVIRONMENTAL EPIGENETICS. 2015;1(1):dvv007

Prenatal lead exposure is associated with decreased cord blood DNA methylation of the glycoprotein VI gene involved in platelet activation and thrombus formation.

Engström K; Rydbeck F; Kippler M; Wojdacz TK; Arifeen S; Vahter M; Broberg K
Article: ENVIRONMENTAL RESEARCH. 2015;136:88-96

Anthroposophic lifestyle influences the concentration of metals in placenta and cord blood.

Fagerstedt S; Kippler M; Scheynius A; Gutzeit C; Mie A; Alm J; Vahter M
Article: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY. 2014;24(5):504-509

Urinary iodine concentrations of pregnant women in rural Bangladesh: a longitudinal study.

Rydbeck F; Bottai M; Tofail F; Persson L-Å; Kippler M
Article: JOURNAL OF INTERNAL MEDICINE. 2014;276(3):248-259

Dietary exposure to polychlorinated biphenyls is associated with increased risk of stroke in women.

Bergkvist C; Kippler M; Larsson SC; Berglund M; Glynn A; Wolk A; Åkesson A
Article: JOURNAL OF NUTRITION. 2014;144(9):1438-1444

Maternal urinary iodine concentration up to 1.0 mg/L is positively associated with birth weight, length, and head circumference of male offspring.

Rydbeck F; Rahman A; Grandér M; Ekström E-C; Vahter M; Kippler M
Article: TOXICOLOGICAL SCIENCES. 2014;141(1):166-175

Arsenic exposure and cell-mediated immunity in pre-school children in rural Bangladesh.

Ahmed S; Moore SE; Kippler M; Gardner R; Hawlader MDH; Wagatsuma Y; Raqib R; Vahter M
Article: METALLOMICS. 2014;6(4):885-891

Cadmium concentrations in human blood and urine are associated with polymorphisms in zinc transporter genes.

Rentschler G; Kippler M; Axmon A; Raqib R; Skerfving S; Vahter M; Broberg K
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2013;177(12):1356-1367

Environmental exposure to metals and children's growth to age 5 years: a prospective cohort study.

Gardner RM; Kippler M; Tofail F; Bottai M; Hamadani J; Grandér M; Nermell B; Palm B; Rasmussen KM; Vahter M
Article: EPIGENETICS. 2013;8(5):494-503

Sex-specific effects of early life cadmium exposure on DNA methylation and implications for birth weight.

Kippler M; Engström K; Mlakar SJ; Bottai M; Ahmed S; Hossain MB; Raqib R; Vahter M; Broberg K
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2013;121(4):467-472

Polymorphisms in iron homeostasis genes and urinary cadmium concentrations among nonsmoking women in Argentina and Bangladesh.

Rentschler G; Kippler M; Axmon A; Raqib R; Ekström E-C; Skerfving S; Vahter M; Broberg K
Article: INTERNATIONAL JOURNAL OF EPIDEMIOLOGY. 2013;42(1):176-185

Early exposure to toxic metals has a limited effect on blood pressure or kidney function in later childhood, rural Bangladesh.

Hawkesworth S; Wagatsuma Y; Kippler M; Fulford AJC; Arifeen SE; Persson L-A; Moore SE; Vahter M
Article: PLOS ONE. 2013;8(9):e74119

Elevated manganese concentrations in drinking water may be beneficial for fetal survival.

Rahman SM; Akesson A; Kippler M; Grandér M; Hamadani JD; Streatfield PK; Persson L-Å; El Arifeen S; Vahter M
Article: REPRODUCTIVE TOXICOLOGY. 2012;34(4):504-511

Environmental exposure to arsenic and cadmium during pregnancy and fetal size: a longitudinal study in rural Bangladesh.

Kippler M; Wagatsuma Y; Rahman A; Nermell B; Persson L-Å; Raqib R; Vahter M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2012;120(10):1462-1468

Early-life cadmium exposure and child development in 5-year-old girls and boys: a cohort study in rural Bangladesh.

Kippler M; Tofail F; Hamadani JD; Gardner RM; Grantham-McGregor SM; Bottai M; Vahter M
Article: TOXICOLOGICAL SCIENCES. 2012;129(2):305-314

In utero arsenic exposure is associated with impaired thymic function in newborns possibly via oxidative stress and apoptosis.

Ahmed S; Ahsan KB; Kippler M; Mily A; Wagatsuma Y; Hoque AMW; Ngom PT; El Arifeen S; Raqib R; Vahter M
Article: ENVIRONMENTAL HEALTH PERSPECTIVES. 2012;120(2):284-289

Maternal cadmium exposure during pregnancy and size at birth: a prospective cohort study.

Kippler M; Tofail F; Gardner R; Rahman A; Hamadani JD; Bottai M; Vahter M
Article: ENVIRONMENTAL RESEARCH. 2012;112:164-170

Early life low-level cadmium exposure is positively associated with increased oxidative stress.

Kippler M; Hossain MB; Lindh C; Moore SE; Kabir I; Vahter M; Broberg K
Article: AMERICAN JOURNAL OF PUBLIC HEALTH. 2011;101 Suppl 1(Suppl 1):S333-S338

Persistent exposure to arsenic via drinking water in rural Bangladesh despite major mitigation efforts.

Gardner R; Hamadani J; Grandér M; Tofail F; Nermell B; Palm B; Kippler M; Vahter M
Journal article: ISEE CONFERENCE ABSTRACTS. 2011;2011(1)

MATERNAL CADMIUM EXPOSURE IN PREGNANCY AFFECTS SIZE AT BIRTH

Kippler M; Tofail F; Gardner R; Hamadani J; Rahman A; Vahter M
Article: REPRODUCTIVE TOXICOLOGY. 2011;31(2):210-218

Arsenic methylation efficiency increases during the first trimester of pregnancy independent of folate status.

Gardner RM; Nermell B; Kippler M; Grandér M; Li L; Ekström E-C; Rahman A; Lönnerdal B; Hoque AMW; Vahter M
Article: ENVIRONMENTAL RESEARCH. 2010;110(7):718-724

Assessment of early-life lead exposure in rural Bangladesh.

Bergkvist C; Kippler M; Hamadani JD; Grandér M; Tofail F; Berglund M; Vahter M
Article: FREE RADICAL BIOLOGY AND MEDICINE. 2010;48(9):1211-1217

Chronic exposure to cadmium and arsenic strongly influences concentrations of 8-oxo-7,8-dihydro-2'-deoxyguanosine in urine.

Engström KS; Vahter M; Johansson G; Lindh CH; Teichert F; Singh R; Kippler M; Nermell B; Raqib R; Strömberg U; Broberg K
Article: TOXICOLOGY LETTERS. 2010;192(2):162-168

Accumulation of cadmium in human placenta interacts with the transport of micronutrients to the fetus.

Kippler M; Hoque AMW; Raqib R; Ohrvik H; Ekström E-C; Vahter M
Article: ENVIRONMENTAL RESEARCH. 2009;109(7):914-921

Factors influencing intestinal cadmium uptake in pregnant Bangladeshi women--a prospective cohort study.

Kippler M; Goessler W; Nermell B; Ekström EC; Lönnerdal B; El Arifeen S; Vahter M
Article: ENVIRONMENTAL SCIENCE & TECHNOLOGY. 2009;43(7):2595-2601

Maternal and early life exposure to manganese in rural Bangladesh.

Ljung KS; Kippler MJ; Goessler W; Grandér GM; Nermell BM; Vahter ME
Article: TOXICOLOGY. 2009;257(1-2):64-69

Cadmium interacts with the transport of essential micronutrients in the mammary gland - a study in rural Bangladeshi women.

Kippler M; Lönnerdal B; Goessler W; Ekström E-C; Arifeen SE; Vahter M
Article: TOXICOLOGY AND APPLIED PHARMACOLOGY. 2007;222(2):221-226

Influence of iron and zinc status on cadmium accumulation in Bangladeshi women.

Kippler M; Ekström E-C; Lönnerdal B; Goessler W; Akesson A; El Arifeen S; Persson L-A; Vahter M
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Review: FOOD & NUTRITION RESEARCH. 2024;68

Manganese - a scoping review for Nordic Nutrition Recommendations 2023.

Kippler M; Oskarsson A
Editorial comment: FRONTIERS IN NUTRITION. 2023;10:1142959

Editorial: Role of toxicants, pollutants, and trace elements in health and nutrition.

Naser AM; Rahman SM; Kippler M
Review: FOOD & NUTRITION RESEARCH. 2023;67

Fluoride - a scoping review for Nordic Nutrition Recommendations 2023.

Kjellevold M; Kippler M
Review: FOOD & NUTRITION RESEARCH. 2023;67

Molybdenum - a scoping review for Nordic Nutrition Recommendations 2023.

Oskarsson A; Kippler M
Conference publication: ISEE CONFERENCE ABSTRACTS. 2022;2022(1)

Early-life exposure to cadmium and onset of puberty in girls: a longitudinal mother-child cohort study in Bangladesh

Malin Igra A; Rahman A; Johansson ALV; Pervin J; Svefors P; El Arifeen S; Vahter M; Persson L-Å; Kippler M
Book chapter: WHOLE GRAINS AND HEALTH. 2021;p. 337-350

Potential Negative Effects of Whole grain Consumption

Kamal‐Eldin A; Åkesson A; Kippler M; Hellenäs K; Scheers N; Sandberg A
Book chapter: A HANDBOOK OF ENVIRONMENTAL TOXICOLOGY: HUMAN DISORDERS AND ECOTOXICOLOGY. 2020;p. 384-393

Cadmium I. Exposure and human health effects: an overview.

Åkesson A; Kippler M
Conference publication: CIRCULATION. 2018;137

Dietary Polychlorinated bipherlyls and Long-chain Omega-3 Fish fatty acids Exposures and Risk of Heart Failure

Kippler M; Vargas CD; Berglund M; Glynn A; Wolk A; Akesson A
Book chapter: ONE CENTURY OF THE DISCOVERY OF ARSENICOSIS IN LATIN AMERICA (1914-2014) AS2014. 2014;p. 8-12

Prospective evaluation of arsenic-related health effects in children

Vahter M; Ahmed S; Kippler M; Raqib R; Broberg K
Conference publication: ALLERGY. 2014;69:197

Anthroposophic lifestyle influences the concentration of toxic metals in placenta and cord blood

Fagerstedt SA; Kippler M; Scheynius A; Mie A; Alm J; Vahter M
Conference publication: TOXICOLOGY LETTERS. 2012;211:S2

Revealing effects of early-life toxic metals exposure - A matter of toxicology, nutrition and epidemiology

Vahter M; Kippler M; Tofail F; Gardner R; Ahmed S; Broberg K; Hamadani J; Raqib R
Conference publication: TOXICOLOGY LETTERS. 2012;211:S143

Maternal cadmium exposure during pregnancy and fetal development

Kippler M; Tofail F; Wagatsuma Y; Gardner R; Hamadani J; Rahman A; Vahter M
Conference publication: TOXICOLOGY LETTERS. 2012;211:S133

Prenatal arsenic exposure is associated with impaired thymic function in newborns

Ahmed S; Kippler M; Wagatsuma Y; Al-Arifeen S; Raqib R; Vahter M
Published conference paper: TOXICOLOGY LETTERS. 2010;198(1):20-25

Burden of cadmium in early childhood: longitudinal assessment of urinary cadmium in rural Bangladesh.

Kippler M; Nermell B; Hamadani J; Tofail F; Moore S; Vahter M
Meeting abstract: TOXICOLOGY LETTERS. 2006;164:S200-S201

Does micronutrient status influence the uptake and accumulation of the toxic metal cadmium?

Kippler M; Ekstrom E-C; Rahman A; Lonnerdal B; El Arifeen S; Persson L-A; Vahter M

Forskningsbidrag

Trade-offs between food safety and food security and its impacts towards the SDGs for children in South Africa, Sweden and Switzerland

Swiss National Science Foundation

1 January 2024 - 31 December 2027
Closer to zero impacts of dietary toxic metals on critical developmental windows

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2023 - 31 December 2025
Effects of early-life exposure to common food and drinking water contaminants on child health and development

Swedish Research Council

1 January 2023 - 31 December 2026
Unraveling underlying modes of action of early-life metal mixture exposure on child growth: integrating epidemiological and experimental evidence

Swedish Research Council

1 January 2023 - 31 December 2025
Mothers, daughters and grandchildren: A cohort study of transgenerational effects of social, nutritional and toxic exposures in early life, a follow-up of the MINIMat trial in rural Bangladesh

Swedish Research Council

1 January 2022 - 31 December 2024
A novel mechanism-based approach for assessment of developmental toxicity of endocrine disruptors

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2021 - 31 December 2024
A limited amount of fluoride promotes early-life dental health but may adversely affect child development

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2020 - 31 December 2022
Can the low content of iodine and selenium in vegetarian and vegan food adversely affect thyroid function in pregnant women and impair development of their children?

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2020 - 31 December 2022
The impact of prenatal and childhood exposure to metals and polycyclic aromatic hydrocarbons on puberty and growth in adolescence: the MINIMat birth cohort in Bangladesh

Swedish Research Council

1 January 2019 - 31 December 2021
A systems toxicology-based approach to reveal early-life dysregulation of body functions by combined exposures to toxic metals

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 December 2018 - 30 November 2022
Effects of early-life exposure to common food and drinking water contaminants on child health and development

Swedish Research Council

1 January 2018 - 31 December 2020
Rice, malnutrition and multiple metals – reasons for impaired child growth and development?

Swedish Research Council

1 January 2016 - 31 December 2018
Is cadmium the "new" lead for our children?

Swedish Research Council

1 January 2016 - 31 December 2018
Early-life environmental lithium and boron exposure and postnatal development; endocrine and epigenetic disruption.

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2016 - 31 December 2018
Impact of environmental cadmium exposure on hormones related to normal child growth and development

Swedish Research Council for Environment Agricultural Sciences and Spatial Planning

1 January 2014 - 31 December 2016

Anställningar

Lektor, Institutet för miljömedicin, Karolinska Institutet, 2020-

Examina och utbildning

Docent, Miljömedicin, Karolinska Institutet, 2020
Medicine Doktorsexamen, Institutet för miljömedicin, Karolinska Institutet, 2009
Medicine Magisterexamen, Karolinska Institutet, 2004

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Examina och utbildning

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