Marc Guitart-Masip

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Forskningsbeskrivning

Jag kombinerar beteendemetoder, beräkningsmodellering, farmakologiska manipuleringar och bildteknik som fMRI, PET och MEG. Mina forskningsintresse består numera av: att förstå den roll som neuromodulatorer dopamin har i motivationsprocessen och beslutsfattande
att förstå sambandet mellan försämringen av det dopaminerga systemet och kognitiv försämring vid normalt åldrandet
att förstå hippocampus roll vid alstring av adaptiva svar i samband med ångest eller nyheter. Dessutom planerar jag en ny studie för att utöka vår förståelse av kopplingen mellan kognitiva funktioner som ligger bakom beslutsfattande och depressionsrisk.

Artiklar

Journal article: SCIENTIFIC REPORTS. 2023;13(1):18451

Anxiety associated with perceived uncontrollable stress enhances expectations of environmental volatility and impairs reward learning.

Guitart-Masip M; Walsh A; Dayan P; Olsson A
Article: CEREBRAL CORTEX. 2023;33(5):1669-1678

Investigating associations of delay discounting with brain structure, working memory, and episodic memory.

Garzón B; Kurth-Nelson Z; Bäckman L; Nyberg L; Guitart-Masip M
Article: NEUROBIOLOGY OF AGING. 2022;118:34-43

Dopamine and reward-related vigor in younger and older adults.

Hird EJ; Beierholm U; De Boer L; Axelsson J; Backman L; Guitart-Masip M
Article: FRONTIERS IN PSYCHOLOGY. 2022;13:786778

Enhanced Instructed Fear Learning in Delusion-Proneness.

Louzolo A; Almeida R; Guitart-Masip M; Björnsdotter M; Lebedev A; Ingvar M; Olsson A; Petrovic P
Article: JOURNAL OF NEURAL TRANSMISSION. 2021;128(11):1705-1720

Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function.

Richter A; de Boer L; Guitart-Masip M; Behnisch G; Seidenbecher CI; Schott BH
Article: NEURON. 2021;109(12):2025-2040.e7

Decision-making ability, psychopathology, and brain connectivity.

Moutoussis M; Garzón B; Neufeld S; Bach DR; Rigoli F; Goodyer I; Bullmore E; NSPN Consortium; Guitart-Masip M; Dolan RJ
Article: BRAIN STRUCTURE & FUNCTION. 2021;226(3):743-758

Role of dopamine and gray matter density in aging effects and individual differences of functional connectomes.

Garzón B; Lövdén M; de Boer L; Axelsson J; Riklund K; Bäckman L; Nyberg L; Guitart-Masip M
Article: SCIENTIFIC REPORTS. 2021;11(1):3416

Overcoming Pavlovian bias in semantic space.

Ereira S; Pujol M; Guitart-Masip M; Dolan RJ; Kurth-Nelson Z
Article: PLOS COMPUTATIONAL BIOLOGY. 2021;17(2):e1008553

Neural signatures of arbitration between Pavlovian and instrumental action selection.

Gershman SJ; Guitart-Masip M; Cavanagh JF
Article: NEUROBIOLOGY OF AGING. 2020;96:49-57

Learning in anticipation of reward and punishment: perspectives across the human lifespan.

Betts MJ; Richter A; de Boer L; Tegelbeckers J; Perosa V; Baumann V; Chowdhury R; Dolan RJ; Seidenbecher C; Schott BH; Düzel E; Guitart-Masip M; Krauel K
Article: CEREBRAL CORTEX. 2020;30(10):5270-5280

Corticostriatal White Matter Integrity and Dopamine D1 Receptor Availability Predict Age Differences in Prefrontal Value Signaling during Reward Learning.

de Boer L; Garzón B; Axelsson J; Riklund K; Nyberg L; Bäckman L; Guitart-Masip M
Article: CEREBRAL CORTEX. 2020;30(6):3573-3589

Variability in Action Selection Relates to Striatal Dopamine 2/3 Receptor Availability in Humans: A PET Neuroimaging Study Using Reinforcement Learning and Active Inference Models.

Adams RA; Moutoussis M; Nour MM; Dahoun T; Lewis D; Illingworth B; Veronese M; Mathys C; de Boer L; Guitart-Masip M; Friston KJ; Howes OD; Roiser JP
Article: CEREBRAL CORTEX. 2020;30(5):3340-3351

The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study.

Perosa V; de Boer L; Ziegler G; Apostolova I; Buchert R; Metzger C; Amthauer H; Guitart-Masip M; Düzel E; Betts MJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(1):261-270

Dorsal striatal dopamine D1 receptor availability predicts an instrumental bias in action learning.

de Boer L; Axelsson J; Chowdhury R; Riklund K; Dolan RJ; Nyberg L; Bäckman L; Guitart-Masip M
Article: CEREBRAL CORTEX. 2018;28(11):3894-3907

Latent-Profile Analysis Reveals Behavioral and Brain Correlates of Dopamine-Cognition Associations.

Lövdén M; Karalija N; Andersson M; Wåhlin A; Axelsson J; Köhncke Y; Jonasson LS; Rieckman A; Papenberg G; Garrett DD; Guitart-Masip M; Salami A; Riklund K; Bäckman L; Nyberg L; Lindenberger U
Article: NEUROSCIENCE LETTERS. 2018;673:92-98

Distinct phenotypes of spontaneous activity and induction of amphetamine sensitization in inbred Roman high- and low-avoidance rats: Vulnerability and protection.

Giménez-Llort L; Guitart-Masip M; Tobeña A; Fernández-Teruel A; Johansson B
Article: PLOS ONE. 2018;13(8):e0201451

Neural activity and fundamental learning, motivated by monetary loss and reward, are intact in mild to moderate major depressive disorder.

Moutoussis M; Rutledge RB; Prabhu G; Hrynkiewicz L; Lam J; Ousdal O-T; Guitart-Masip M; Fonagy P; Dolan RJ
Article: ELIFE. 2017;6:e26424

Attenuation of dopamine-modulated prefrontal value signals underlies probabilistic reward learning deficits in old age.

de Boer L; Axelsson J; Riklund K; Nyberg L; Dayan P; Bäckman L; Guitart-Masip M
Article: CEREBRAL CORTEX. 2017;27(1):201-215

Parsing the Role of the Hippocampus in Approach-Avoidance Conflict.

Loh E; Kurth-Nelson Z; Berron D; Dayan P; Duzel E; Dolan R; Guitart-Masip M
Article: CEREBRAL CORTEX. 2016;26(5):2074-2083

BOLD Variability is Related to Dopaminergic Neurotransmission and Cognitive Aging.

Guitart-Masip M; Salami A; Garrett D; Rieckmann A; Lindenberger U; Bäckman L
Article: CEREBRAL CORTEX. 2015;25(12):4908-4917

Basal Ganglia Activity Mirrors a Benefit of Action and Reward on Long-Lasting Event Memory.

Koster R; Guitart-Masip M; Dolan RJ; Düzel E
Article: CEREBRAL CORTEX. 2015;25(10):3629-3639

Dopamine, Salience, and Response Set Shifting in Prefrontal Cortex.

Shiner T; Symmonds M; Guitart-Masip M; Fleming SM; Friston KJ; Dolan RJ
Article: PLOS COMPUTATIONAL BIOLOGY. 2015;11(9):e1004463

Model-Based Reasoning in Humans Becomes Automatic with Training.

Economides M; Kurth-Nelson Z; Lübbert A; Guitart-Masip M; Dolan RJ
Article: JOURNAL OF NEUROLOGY. 2015;262(6):1541-1547

Deep brain stimulation of the subthalamic nucleus modulates reward processing and action selection in Parkinson patients.

Wagenbreth C; Zaehle T; Galazky I; Voges J; Guitart-Masip M; Heinze H-J; Düzel E
Article: NEUROIMAGE. 2015;109:206-216

Arbitration between controlled and impulsive choices.

Economides M; Guitart-Masip M; Kurth-Nelson Z; Dolan RJ
Article: CEREBRAL CORTEX. 2014;24(5):1351-1360

Pharmacological dissociation of novelty responses in the human brain.

Bunzeck N; Guitart-Masip M; Dolan RJ; Duzel E
Article: CURRENT BIOLOGY. 2014;24(5):541-547

Human hippocampus arbitrates approach-avoidance conflict.

Bach DR; Guitart-Masip M; Packard PA; Miró J; Falip M; Fuentemilla L; Dolan RJ
Article: PSYCHOPHARMACOLOGY. 2014;231(5):955-966

Differential, but not opponent, effects of L -DOPA and citalopram on action learning with reward and punishment.

Guitart-Masip M; Economides M; Huys QJM; Frank MJ; Chowdhury R; Duzel E; Dayan P; Dolan RJ
Article: JOURNAL OF NEUROSCIENCE. 2014;34(9):3340-3349

Anterior cingulate cortex instigates adaptive switches in choice by integrating immediate and delayed components of value in ventromedial prefrontal cortex.

Economides M; Guitart-Masip M; Kurth-Nelson Z; Dolan RJ
Article: FRONTIERS IN SYSTEMS NEUROSCIENCE. 2014;8:140

Valenced action/inhibition learning in humans is modulated by a genetic variant linked to dopamine D2 receptor expression.

Richter A; Guitart-Masip M; Barman A; Libeau C; Behnisch G; Czerney S; Schanze D; Assmann A; Klein M; Düzel E; Zenker M; Seidenbecher CI; Schott BH
Article: JOURNAL OF NEUROSCIENCE. 2013;33(46):18087-18097

Preparing for selective inhibition within frontostriatal loops.

Smittenaar P; Guitart-Masip M; Lutti A; Dolan RJ
Article: NEUROBIOLOGY OF AGING. 2013;34(10):2261-2270

Structural integrity of the substantia nigra and subthalamic nucleus predicts flexibility of instrumental learning in older-age individuals.

Chowdhury R; Guitart-Masip M; Lambert C; Dolan RJ; Düzel E
Article: NEUROIMAGE. 2013;78:135-144

Electrophysiological correlates of anticipating improbable but desired events.

Fuentemilla L; Cucurell D; Marco-Pallarés J; Guitart-Masip M; Morís J; Rodríguez-Fornells A
Article: NEUROPSYCHOPHARMACOLOGY. 2013;38(8):1495-1503

Dopamine modulates reward-related vigor.

Beierholm U; Guitart-Masip M; Economides M; Chowdhury R; Düzel E; Dolan R; Dayan P
Article: JOURNAL OF NEUROSCIENCE. 2013;33(19):8541-8548

Frontal theta overrides pavlovian learning biases.

Cavanagh JF; Eisenberg I; Guitart-Masip M; Huys Q; Frank MJ
Article: NATURE NEUROSCIENCE. 2013;16(5):648-653

Dopamine restores reward prediction errors in old age.

Chowdhury R; Guitart-Masip M; Lambert C; Dayan P; Huys Q; Düzel E; Dolan RJ
Article: JOURNAL OF NEUROSCIENCE. 2013;33(14):6160-6169

Effort and valuation in the brain: the effects of anticipation and execution.

Kurniawan IT; Guitart-Masip M; Dayan P; Dolan RJ
Article: JOURNAL OF NEUROSCIENCE. 2013;33(2):442-451

Synchronization of medial temporal lobe and prefrontal rhythms in human decision making.

Guitart-Masip M; Barnes GR; Horner A; Bauer M; Dolan RJ; Duzel E
Article: FRONTIERS IN NEUROSCIENCE. 2013;7:228

Manipulating the contribution of approach-avoidance to the perturbation of economic choice by valence.

Wright ND; Morris LS; Guitart-Masip M; Dolan RJ
Article: JOURNAL OF NEUROSCIENCE. 2012;32(41):14193-14204

Dopamine modulates episodic memory persistence in old age.

Chowdhury R; Guitart-Masip M; Bunzeck N; Dolan RJ; Düzel E
Article: CURRENT BIOLOGY. 2012;22(16):1477-1481

How dopamine enhances an optimism bias in humans.

Sharot T; Guitart-Masip M; Korn CW; Chowdhury R; Dolan RJ
Article: NEUROIMAGE. 2012;62(1):154-166

Go and no-go learning in reward and punishment: interactions between affect and effect.

Guitart-Masip M; Huys QJM; Fuentemilla L; Dayan P; Duzel E; Dolan RJ
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(19):7511-7516

Action controls dopaminergic enhancement of reward representations.

Guitart-Masip M; Chowdhury R; Sharot T; Dayan P; Duzel E; Dolan RJ
Article: SCIENTIFIC REPORTS. 2012;2:593

Human responses to unfairness with primary rewards and their biological limits.

Wright ND; Hodgson K; Fleming SM; Symmonds M; Guitart-Masip M; Dolan RJ
Article: JOURNAL OF COGNITIVE NEUROSCIENCE. 2011;23(12):3933-3938

Vigor in the face of fluctuating rates of reward: an experimental examination.

Guitart-Masip M; Beierholm UR; Dolan R; Duzel E; Dayan P
Article: JOURNAL OF NEUROSCIENCE. 2011;31(36):12816-12822

Contextual novelty modulates the neural dynamics of reward anticipation.

Bunzeck N; Guitart-Masip M; Dolan RJ; Düzel E
Article: JOURNAL OF NEUROSCIENCE. 2011;31(21):7867-7875

Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain.

Guitart-Masip M; Fuentemilla L; Bach DR; Huys QJM; Dayan P; Dolan RJ; Duzel E
Article: PHYSIOLOGY & BEHAVIOR. 2011;103(2):148-156

Two-way avoidance acquisition is negatively related to conditioned freezing and positively associated with startle reactions: a dissection of anxiety and fear in genetically heterogeneous rats.

Vicens-Costa E; Martínez-Membrives E; López-Aumatell R; Guitart-Masip M; Cañete T; Blázquez G; Tobeña A; Fernández-Teruel A
Article: FRONTIERS IN NEUROSCIENCE. 2011;5:81

Dopamine and effort-based decision making.

Kurniawan IT; Guitart-Masip M; Dolan RJ
Article: NEUROIMAGE. 2010;53(1):206-214

Conditioned associations and economic decision biases.

Guitart-Masip M; Talmi D; Dolan R
Article: JOURNAL OF NEUROSCIENCE. 2010;30(5):1721-1726

Contextual novelty changes reward representations in the striatum.

Guitart-Masip M; Bunzeck N; Stephan KE; Dolan RJ; Düzel E
Article: BEHAVIOURAL BRAIN RESEARCH. 2009;202(1):92-101

Unlearned anxiety predicts learned fear: a comparison among heterogeneous rats and the Roman rat strains.

López-Aumatell R; Vicens-Costa E; Guitart-Masip M; Martínez-Membrives E; Valdar W; Johannesson M; Cañete T; Blázquez G; Driscoll P; Flint J; Tobeña A; Fernández-Teruel A
Article: GENOME RESEARCH. 2009;19(1):150-158

A resource for the simultaneous high-resolution mapping of multiple quantitative trait loci in rats: the NIH heterogeneous stock.

Johannesson M; Lopez-Aumatell R; Stridh P; Diez M; Tuncel J; Blázquez G; Martinez-Membrives E; Cañete T; Vicens-Costa E; Graham D; Copley RR; Hernandez-Pliego P; Beyeen AD; Ockinger J; Fernández-Santamaría C; Gulko PS; Brenner M; Tobeña A; Guitart-Masip M; Giménez-Llort L; Dominiczak A; Holmdahl R; Gauguier D; Olsson T; Mott R; Valdar W; Redei EE; Fernández-Teruel A; Flint J
Article: NEUROCHEMICAL RESEARCH. 2008;33(10):2062-2069

Effects of naltrexone and acamprosate on alcohol-induced NGFI-A expression in mouse brain.

Lindholm J; Guitart-Masip M; Hassankhali H; Landgren S; Nicoleau C; Giménez-Llort L; Terenius L; Ogren SO; Johansson B
Article: BEHAVIOURAL BRAIN RESEARCH. 2008;188(1):41-55

Fearfulness in a large N/Nih genetically heterogeneous rat stock: differential profiles of timidity and defensive flight in males and females.

Lopez-Aumatell R; Guitart-Masip M; Vicens-Costa E; Gimenez-Llort L; Valdar W; Johannesson M; Flint J; Tobeña A; Fernandez-Teruel A
Article: NEUROSCIENCE. 2008;151(1):195-208

Regional adaptations in PSD-95, NGFI-A and secretogranin gene transcripts related to vulnerability to behavioral sensitization to amphetamine in the Roman rat strains.

Guitart-Masip M; Johansson B; Cañete T; Fernández-Teruel A; Tobeña A; Terenius L; Giménez-Llort L
Article: PSYCHOPHARMACOLOGY. 2008;196(1):39-49

Divergent effect of the selective D3 receptor agonist pd-128,907 on locomotor activity in Roman high- and low-avoidance rats: relationship to NGFI-A gene expression in the Calleja islands.

Guitart-Masip M; Johansson B; Fernández-Teruel A; Tobeña A; Giménez-Llort L
Article: NEUROSCIENCE. 2006;142(4):1231-1243

Divergent anatomical pattern of D1 and D3 binding and dopamine- and cyclic AMP-regulated phosphoprotein of 32 kDa mRNA expression in the Roman rat strains: Implications for drug addiction.

Guitart-Masip M; Johansson B; Fernández-Teruel A; Cañete T; Tobeña A; Terenius L; Giménez-Llort L
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2006;23(2):531-540

Reduced ethanol response in the alcohol-preferring RHA rats and neuropeptide mRNAs in relevant structures.

Guitart-Masip M; Giménez-Llort L; Fernández-Teruel A; Cañete T; Tobeña A; Ogren SO; Terenius L; Johansson B
Article: PHYSIOLOGY & BEHAVIOR. 2005;86(4):458-466

Two distinctive apomorphine-induced phenotypes in the Roman high- and low-avoidance rats.

Giménez-Llort L; Cañete T; Guitart-Masip M; Fernández-Teruel A; Tobeña A
Visa fler

Alla övriga publikationer

Review: EUROPEAN JOURNAL OF AGEING. 2022;19(4):945-952

A link between age, affect, and predictions?

Trapp S; Guitart-Masip M; Schröger E
Corrigendum: JOURNAL OF NEURAL TRANSMISSION. 2022;129(1):117-122

Correction to: Motivational learning biases are differentially modulated by genetic determinants of striatal and prefrontal dopamine function.

Richter A; de Boer L; Guitart-Masip M; Behnisch G; Seidenbecher CI; Schott BH
Corrigendum: CEREBRAL CORTEX. 2020;30(6):3857

Corrigendum: The Role of the Striatum in Learning to Orthogonalize Action and Valence: A Combined PET and 7 T MRI Aging Study.

Perosa V; de Boer L; Ziegler G; Apostolova I; Buchert R; Metzger C; Amthauer H; Guitart-Masip M; Düzel E; Betts MJ
Corrigendum: FRONTIERS IN SYSTEMS NEUROSCIENCE. 2015;9:36

Corrigendum: Valenced action/inhibition learning in humans is modulated by a genetic variant linked to dopamine D2 receptor expression.

Richter A; Guitart-Masip M; Barman A; Libeau C; Behnisch G; Czerney S; Schanze D; Assmann A; Klein M; Düzel E; Zenker M; Seidenbecher C; Schott BH
Corrigendum: NATURE NEUROSCIENCE. 2014;17(12):1840

Dopamine restores reward prediction errors in old age (vol 16, pg 648, 2013)

Chowdhury R; Guitart-Masip M; Lambert C; Dayan P; Huys Q; Duezel E; Dolan RJ
Corrigendum: CURRENT BIOLOGY. 2014;24(12):1435

Human Hippocampus Arbitrates Approach-Avoidance Conflict.

Bach DR; Guitart-Masip M; Packard PA; Miró J; Falip M; Fuentemilla L; Dolan RJ
Review: TRENDS IN COGNITIVE SCIENCES. 2014;18(4):194-202

Action versus valence in decision making.

Guitart-Masip M; Duzel E; Dolan R; Dayan P
Editorial comment: NEURON. 2013;79(1):9-11

Not so uncertain at last: locus coeruleus and decision making.

Duzel E; Guitart-Masip M
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2010;34(5):660-669

NOvelty-related motivation of anticipation and exploration by dopamine (NOMAD): implications for healthy aging.

Düzel E; Bunzeck N; Guitart-Masip M; Düzel S
Review: PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY. 2009;33(8):1537-1545

Neural correlates of impaired emotional discrimination in borderline personality disorder: an fMRI study.

Guitart-Masip M; Pascual JC; Carmona S; Hoekzema E; Bergé D; Pérez V; Soler J; Soliva JC; Rovira M; Bulbena A; Vilarroya O
Review: TRENDS IN NEUROSCIENCES. 2009;32(6):321-328

Functional imaging of the human dopaminergic midbrain.

Düzel E; Bunzeck N; Guitart-Masip M; Wittmann B; Schott BH; Tobler PN

Anställningar

Senior Forskare, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2022-

Examina och utbildning

Docent, Neurovetenskap, Karolinska Institutet, 2018

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Anställningar

Examina och utbildning

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