Konstantinos Kostulas

Article: EUROPEAN STROKE JOURNAL. 2019;4(4):307-317

Consensus statements and recommendations from the ESO-Karolinska Stroke Update Conference, Stockholm 11-13 November 2018.

Ahmed N; Audebert H; Turc G; Cordonnier C; Christensen H; Sacco S; Sandset EC; Ntaios G; Charidimou A; Toni D; Pristipino C; Köhrmann M; Kuramatsu JB; Thomalla G; Mikulik R; Ford GA; Martí-Fàbregas J; Fischer U; Thoren M; Lundström E; Rinkel GJ; van der Worp HB; Matusevicius M; Tsivgoulis G; Milionis H; Rubiera M; Hart R; Moreira T; Lantz M; Sjöstrand C; Andersen G; Schellinger P; Kostulas K; Sunnerhagen KS; Keselman B; Korompoki E; Purrucker J; Khatri P; Whiteley W; Berge E; Mazya M; Dippel DW; Mustanoja S; Rasmussen M; Söderqvist ÅK; Escudero-Martínez I; Steiner T

Article: NEW ENGLAND JOURNAL OF MEDICINE. 2019;380(20):1906-1917

Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.

Diener H-C; Sacco RL; Easton JD; Granger CB; Bernstein RA; Uchiyama S; Kreuzer J; Cronin L; Cotton D; Grauer C; Brueckmann M; Chernyatina M; Donnan G; Ferro JM; Grond M; Kallmünzer B; Krupinski J; Lee B-C; Lemmens R; Masjuan J; Odinak M; Saver JL; Schellinger PD; Toni D; Toyoda K; RE-SPECT ESUS Steering Committee and Investigators

Article: JAMA NEUROLOGY. 2019;76(4):480-491

Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.

Marini S; Crawford K; Morotti A; Lee MJ; Pezzini A; Moomaw CJ; Flaherty ML; Montaner J; Roquer J; Jimenez-Conde J; Giralt-Steinhauer E; Elosua R; Cuadrado-Godia E; Soriano-Tarraga C; Slowik A; Jagiella JM; Pera J; Urbanik A; Pichler A; Hansen BM; McCauley JL; Tirschwell DL; Selim M; Brown DL; Silliman SL; Worrall BB; Meschia JF; Kidwell CS; Testai FD; Kittner SJ; Schmidt H; Enzinger C; Deary IJ; Rannikmae K; Samarasekera N; Al-Shahi Salman R; Sudlow CL; Klijn CJM; van Nieuwenhuizen KM; Fernandez-Cadenas I; Delgado P; Norrving B; Lindgren A; Goldstein JN; Viswanathan A; Greenberg SM; Falcone GJ; Biffi A; Langefeld CD; Woo D; Rosand J; Anderson CD; International Stroke Genetics Consortium

Article: NEUROLOGY. 2019;92(11):e1176-e1187

Relative effects of LDL-C on ischemic stroke and coronary disease: A Mendelian randomization study.

Valdes-Marquez E; Parish S; Clarke R; Stari T; Worrall BB; METASTROKE Consortium of the ISGC,; Hopewell JC

Article: NEUROLOGY. 2019;92(5):e486-e503

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Chauhan G; Adams HHH; Satizabal CL; Bis JC; Teumer A; Sargurupremraj M; Hofer E; Trompet S; Hilal S; Smith AV; Jian X; Malik R; Traylor M; Pulit SL; Amouyel P; Mazoyer B; Zhu Y-C; Kaffashian S; Schilling S; Beecham GW; Montine TJ; Schellenberg GD; Kjartansson O; Guðnason V; Knopman DS; Griswold ME; Windham BG; Gottesman RF; Mosley TH; Schmidt R; Saba Y; Schmidt H; Takeuchi F; Yamaguchi S; Nabika T; Kato N; Rajan KB; Aggarwal NT; De Jager PL; Evans DA; Psaty BM; Rotter JI; Rice K; Lopez OL; Liao J; Chen C; Cheng C-Y; Wong TY; Ikram MK; van der Lee SJ; Amin N; Chouraki V; DeStefano AL; Aparicio HJ; Romero JR; Maillard P; DeCarli C; Wardlaw JM; Hernández MDCV; Luciano M; Liewald D; Deary IJ; Starr JM; Bastin ME; Muñoz Maniega S; Slagboom PE; Beekman M; Deelen J; Uh H-W; Lemmens R; Brodaty H; Wright MJ; Ames D; Boncoraglio GB; Hopewell JC; Beecham AH; Blanton SH; Wright CB; Sacco RL; Wen W; Thalamuthu A; Armstrong NJ; Chong E; Schofield PR; Kwok JB; van der Grond J; Stott DJ; Ford I; Jukema JW; Vernooij MW; Hofman A; Uitterlinden AG; van der Lugt A; Wittfeld K; Grabe HJ; Hosten N; von Sarnowski B; Völker U; Levi C; Jimenez-Conde J; Sharma P; Sudlow CLM; Rosand J; Woo D; Cole JW; Meschia JF; Slowik A; Thijs V; Lindgren A; Melander O; Grewal RP; Rundek T; Rexrode K; Rothwell PM; Arnett DK; Jern C; Johnson JA; Benavente OR; Wasssertheil-Smoller S; Lee J-M; Wong Q; Mitchell BD; Rich SS; McArdle PF; Geerlings MI; van der Graaf Y; de Bakker PIW; Asselbergs FW; Srikanth V; Thomson R; McWhirter R; Moran C; Callisaya M; Phan T; Rutten-Jacobs LCA; Bevan S; Tzourio C; Mather KA; Sachdev PS; van Duijn CM; Worrall BB; Dichgans M; Kittner SJ; Markus HS; Ikram MA; Fornage M; Launer LJ; Seshadri S; Longstreth WT; Debette S; Stroke Genetics Network (SiGN), the International

Article: NEUROLOGY-GENETICS. 2018;4(6):e293

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes.

Pulit SL; Weng L-C; McArdle PF; Trinquart L; Choi SH; Mitchell BD; Rosand J; de Bakker PIW; Benjamin EJ; Ellinor PT; Kittner SJ; Lubitz SA; Anderson CD

Article: NEW ENGLAND JOURNAL OF MEDICINE. 2017;377(11):1033-1042

Patent Foramen Ovale Closure or Antiplatelet Therapy for Cryptogenic Stroke.

Søndergaard L; Kasner SE; Rhodes JF; Andersen G; Iversen HK; Nielsen-Kudsk JE; Settergren M; Sjöstrand C; Roine RO; Hildick-Smith D; Spence JD; Thomassen L; Gore REDUCE Clinical Study Investigators

Article: BMJ OPEN. 2017;7(9):e015244

Hospital comparison of stroke care in Sweden: a register-based study.

Lekander I; Willers C; Ekstrand E; von Euler M; Fagervall-Yttling B; Henricson L; Kostulas K; Lilja M; Sunnerhagen KS; Teichert J; Pessah-Rasmussen H

Article: JOURNAL OF INTERVENTIONAL CARDIOLOGY. 2017;30(3):242-248

Impaired endothelial function in patients with cryptogenic stroke and patent foramen ovale is not affected by closure.

Lantz M; Kostulas K; Settergren M; Sjöstrand C

Article: PLOS ONE. 2017;12(8):e0183571

Elevated plasma homocysteine upon ischemic stroke is associated with increased long-term mortality in women.

Markaki I; Klironomos S; Kostulas K; Sjostrand C

Article: NEUROLOGY. 2016;86(2):146-153

Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.

Traylor M; Zhang CR; Adib-Samii P; Devan WJ; Parsons OE; Lanfranconi S; Gregory S; Cloonan L; Falcone GJ; Radmanesh F; Fitzpatrick K; Kanakis A; Barrick TR; Moynihan B; Lewis CM; Boncoraglio GB; Lemmens R; Thijs V; Sudlow C; Wardlaw J; Rothwell PM; Meschia JF; Worrall BB; Levi C; Bevan S; Furie KL; Dichgans M; Rosand J; Markus HS; Rost N; International Stroke Genetics Consortium

Article: ACTA NEUROLOGICA SCANDINAVICA. 2015;131(5):290-297

Prevalence of migraine headache in an in-patient stroke population.

Lantz M; Kostulas K; Waldenlind E; Sjöstrand C

Article: BIOMED RESEARCH INTERNATIONAL. 2015;2015:613247-12

Electrical Bioimpedance Spectroscopy on Acute Unilateral Stroke Patients: Initial Observations regarding Differences between Sides.

Seoane F; Reza Atefi S; Tomner J; Kostulas K; Lindecrantz K

Article: JOURNAL OF CLINICAL NEUROLOGY. 2014;10(2):108-118

Idiopathic small fiber neuropathy: phenotype, etiologies, and the search for fabry disease.

Samuelsson K; Kostulas K; Vrethem M; Rolfs A; Press R

Article: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES. 2014;23(1):e47-e53

High cholesterol levels are associated with improved long-term survival after acute ischemic stroke.

Markaki I; Nilsson U; Kostulas K; Sjöstrand C

Article: JOURNAL OF STROKE & CEREBROVASCULAR DISEASES. 2013;22(6):841-845

Ischemic stroke and patent foramen ovale: risk factors and genetic profile.

Lantz M; Sjöstrand C; Kostulas K

Article: ACTA NEUROLOGICA SCANDINAVICA. 2013;127(4):e18-e23

Migraine-related ischemic stroke?

Lantz M; Kostulas K; Sjöstrand C

Article: LANCET NEUROLOGY. 2012;11(11):951-962

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

Traylor M; Farrall M; Holliday EG; Sudlow C; Hopewell JC; Cheng Y-C; Fornage M; Ikram MA; Malik R; Bevan S; Thorsteinsdottir U; Nalls MA; Longstreth W; Wiggins KL; Yadav S; Parati EA; Destefano AL; Worrall BB; Kittner SJ; Khan MS; Reiner AP; Helgadottir A; Achterberg S; Fernandez-Cadenas I; Abboud S; Schmidt R; Walters M; Chen W-M; Ringelstein EB; O'Donnell M; Ho WK; Pera J; Lemmens R; Norrving B; Higgins P; Benn M; Sale M; Kuhlenbäumer G; Doney ASF; Vicente AM; Delavaran H; Algra A; Davies G; Oliveira SA; Palmer CNA; Deary I; Schmidt H; Pandolfo M; Montaner J; Carty C; de Bakker PIW; Kostulas K; Ferro JM; van Zuydam NR; Valdimarsson E; Nordestgaard BG; Lindgren A; Thijs V; Slowik A; Saleheen D; Paré G; Berger K; Thorleifsson G; Australian Stroke Genetics Collaborative, Wellcome; Hofman A; Mosley TH; Mitchell BD; Furie K; Clarke R; Levi C; Seshadri S; Gschwendtner A; Boncoraglio GB; Sharma P; Bis JC; Gretarsdottir S; Psaty BM; Rothwell PM; Rosand J; Meschia JF; Stefansson K; Dichgans M; Markus HS; International Stroke Genetics Consortium

Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2012;320(1-2):110-117

Evolution of microglial activation in ischaemic core and peri-infarct regions after stroke: a PET study with the TSPO molecular imaging biomarker [((11))C]vinpocetine.

Gulyás B; Tóth M; Schain M; Airaksinen A; Vas A; Kostulas K; Lindström P; Hillert J; Halldin C

Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2012;60(8):722-729

Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.

Helgadottir A; Gretarsdottir S; Thorleifsson G; Holm H; Patel RS; Gudnason T; Jones GT; van Rij AM; Eapen DJ; Baas AF; Tregouet D-A; Morange P-E; Emmerich J; Lindblad B; Gottsäter A; Kiemeny LA; Lindholt JS; Sakalihasan N; Ferrell RE; Carey DJ; Elmore JR; Tsao PS; Grarup N; Jørgensen T; Witte DR; Hansen T; Pedersen O; Pola R; Gaetani E; Magnadottir HB; Wijmenga C; Tromp G; Ronkainen A; Ruigrok YM; Blankensteijn JD; Mueller T; Wells PS; Corral J; Soria JM; Souto JC; Peden JF; Jalilzadeh S; Mayosi BM; Keavney B; Strawbridge RJ; Sabater-Lleal M; Gertow K; Baldassarre D; Nyyssönen K; Rauramaa R; Smit AJ; Mannarino E; Giral P; Tremoli E; de Faire U; Humphries SE; Hamsten A; Haraldsdottir V; Olafsson I; Magnusson MK; Samani NJ; Levey AI; Markus HS; Kostulas K; Dichgans M; Berger K; Kuhlenbäumer G; Ringelstein EB; Stoll M; Seedorf U; Rothwell PM; Powell JT; Kuivaniemi H; Onundarson PT; Valdimarsson E; Matthiasson SE; Gudbjartsson DF; Thorgeirsson G; Quyyumi AA; Watkins H; Farrall M; Thorsteinsdottir U; Stefansson K

Article: CURRENT RADIOPHARMACEUTICALS. 2012;5(1):19-28

Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine.

Gulyas B; Toth M; Vas A; Shchukin E; Kostulas K; Hillert J; Halldin C

Article: LANCET. 2011;377(9767):741-750

The angiotensin-receptor blocker candesartan for treatment of acute stroke (SCAST): a randomised, placebo-controlled, double-blind trial.

Sandset EC; Bath PMW; Boysen G; Jatuzis D; Kõrv J; Lüders S; Murray GD; Richter PS; Roine RO; Terént A; Thijs V; Berge E; SCAST Study Group

Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2009;70(5):475-480

Common CCR 5 polymorphism in stroke: the CCR 5 delta32 polymorphism differentiates cardioembolism from other aetiologies of ischaemic cerebrovascular diseases.

Kostulas N; Markaki I; Kostulas V; Hillert J; Kostulas K

Article: NATURE GENETICS. 2009;41(8):876-878

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke.

Gudbjartsson DF; Holm H; Gretarsdottir S; Thorleifsson G; Walters GB; Thorgeirsson G; Gulcher J; Mathiesen EB; Njølstad I; Nyrnes A; Wilsgaard T; Hald EM; Hveem K; Stoltenberg C; Kucera G; Stubblefield T; Carter S; Roden D; Ng MCY; Baum L; So WY; Wong KS; Chan JCN; Gieger C; Wichmann H-E; Gschwendtner A; Dichgans M; Kuhlenbäumer G; Berger K; Ringelstein EB; Bevan S; Markus HS; Kostulas K; Hillert J; Sveinbjörnsdóttir S; Valdimarsson EM; Løchen M-L; Ma RCW; Darbar D; Kong A; Arnar DO; Thorsteinsdottir U; Stefansson K

Article: ANNALS OF NEUROLOGY. 2008;64(4):402-409

Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.

Gretarsdottir S; Thorleifsson G; Manolescu A; Styrkarsdottir U; Helgadottir A; Gschwendtner A; Kostulas K; Kuhlenbäumer G; Bevan S; Jonsdottir T; Bjarnason H; Saemundsdottir J; Palsson S; Arnar DO; Holm H; Thorgeirsson G; Valdimarsson EM; Sveinbjörnsdottir S; Gieger C; Berger K; Wichmann H-E; Hillert J; Markus H; Gulcher JR; Ringelstein EB; Kong A; Dichgans M; Gudbjartsson DF; Thorsteinsdottir U; Stefansson K

Article: ACTA NEUROLOGICA SCANDINAVICA. 2008;118(3):146-152

Genetic profile of ischemic cerebrovascular disease and carotid stenosis.

Kostulas K; Brophy VH; Moraitis K; Manolescu A; Kostulas V; Gretarsdottir S; Cheng S; Hillert J

Article: NATURE GENETICS. 2008;40(7):886-891

ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma.

Gudbjartsson DF; Sulem P; Stacey SN; Goldstein AM; Rafnar T; Sigurgeirsson B; Benediktsdottir KR; Thorisdottir K; Ragnarsson R; Sveinsdottir SG; Magnusson V; Lindblom A; Kostulas K; Botella-Estrada R; Soriano V; Juberías P; Grasa M; Saez B; Andres R; Scherer D; Rudnai P; Gurzau E; Koppova K; Kiemeney LA; Jakobsdottir M; Steinberg S; Helgason A; Gretarsdottir S; Tucker MA; Mayordomo JI; Nagore E; Kumar R; Hansson J; Olafsson JH; Gulcher J; Kong A; Thorsteinsdottir U; Stefansson K

Article: NATURE GENETICS. 2008;40(2):217-224

The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.

Helgadottir A; Thorleifsson G; Magnusson KP; Grétarsdottir S; Steinthorsdottir V; Manolescu A; Jones GT; Rinkel GJE; Blankensteijn JD; Ronkainen A; Jääskeläinen JE; Kyo Y; Lenk GM; Sakalihasan N; Kostulas K; Gottsäter A; Flex A; Stefansson H; Hansen T; Andersen G; Weinsheimer S; Borch-Johnsen K; Jorgensen T; Shah SH; Quyyumi AA; Granger CB; Reilly MP; Austin H; Levey AI; Vaccarino V; Palsdottir E; Walters GB; Jonsdottir T; Snorradottir S; Magnusdottir D; Gudmundsson G; Ferrell RE; Sveinbjornsdottir S; Hernesniemi J; Niemelä M; Limet R; Andersen K; Sigurdsson G; Benediktsson R; Verhoeven ELG; Teijink JAW; Grobbee DE; Rader DJ; Collier DA; Pedersen O; Pola R; Hillert J; Lindblad B; Valdimarsson EM; Magnadottir HB; Wijmenga C; Tromp G; Baas AF; Ruigrok YM; van Rij AM; Kuivaniemi H; Powell JT; Matthiasson SE; Gulcher JR; Thorgeirsson G; Kong A; Thorsteinsdottir U; Stefansson K

Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2008;264(1-2):9-17

Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients.

Vas A; Shchukin Y; Karrenbauer VD; Cselényi Z; Kostulas K; Hillert J; Savic I; Takano A; Halldin C; Gulyás B

Article: JOURNAL OF THE NEUROLOGICAL SCIENCES. 2007;263(1-2):113-117

PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden.

Kostulas K; Gretarsdottir S; Kostulas V; Manolescu A; Helgadottir A; Thorleifsson G; Gudmundsson LJ; Thorsteinsdottir U; Gulcher JR; Stefansson K; Hillert J

Article: NATURE. 2007;448(7151):353-357

Variants conferring risk of atrial fibrillation on chromosome 4q25.

Gudbjartsson DF; Arnar DO; Helgadottir A; Gretarsdottir S; Holm H; Sigurdsson A; Jonasdottir A; Baker A; Thorleifsson G; Kristjansson K; Palsson A; Blondal T; Sulem P; Backman VM; Hardarson GA; Palsdottir E; Helgason A; Sigurjonsdottir R; Sverrisson JT; Kostulas K; Ng MCY; Baum L; So WY; Wong KS; Chan JCN; Furie KL; Greenberg SM; Sale M; Kelly P; MacRae CA; Smith EE; Rosand J; Hillert J; Ma RCW; Ellinor PT; Thorgeirsson G; Gulcher JR; Kong A; Thorsteinsdottir U; Stefansson K

Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2006;64(4):412-419

Increased soluble 4-1BB ligand (4-1BBL) levels in peripheral blood of patients with multiple sclerosis.

Liu G-Z; Gomes AC; Putheti P; Karrenbauer V; Kostulas K; Press R; Hillert J; Hjelmström P; Gao X-G

Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1999;29(6):478-483

An angiotensin-converting enzyme gene polymorphism suggests a genetic distinction between ischaemic stroke and carotid stenosis.

Kostulas K; Huang WX; Crisby M; Jin YP; He B; Lannfelt L; Eggertsen G; Kostulas V; Hillert J

Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1998;28(4):285-289

A methylenetetrahydrofolate reductase gene polymorphism in ischaemic stroke and in carotid artery stenosis.

Kostulas K; Crisby M; Huang WX; Lannfelt L; Hagenfeldt L; Eggertsen G; Kostulas V; Hillert J

Article: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. 1997;27(9):740-742

Lipoprotein lipase gene polymorphisms in ischaemic stroke and carotid stenosis.

Huang P; Kostulas K; Huang WX; Crisby M; Kostulas V; Hillert J