Juan Pablo Lopez

Publikationer
Populärvetenskap och samverkan

Artiklar

Journal article: NEUROSCIENCE APPLIED. 2024;3:103929

Knowledge gaps in psychedelic medicalisation: Preclinical and neuroimaging mechanisms

McCulloch DE-W; Lopez JP; Dalla C; Castrén E; Erritzoe D; Frokjaer VG; Lundberg J; Preller KH; Fisher PM; Knudsen GM
Journal article: SCIENCE ADVANCES. 2023;9(48):eadj3793

Early life adversity shapes social subordination and cell type-specific transcriptomic patterning in the ventral hippocampus.

Kos A; Lopez JP; Bordes J; de Donno C; Dine J; Brivio E; Karamihalev S; Luecken MD; Almeida-Correa S; Gasperoni S; Dick A; Miranda L; Büttner M; Stoffel R; Flachskamm C; Theis FJ; Schmidt MV; Chen A
Article: STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS. 2023;26(1):2186141

Increasing resolution in stress neurobiology: from single cells to complex group behaviors.

Miranda L; Bordes J; Gasperoni S; Lopez JP
Article: NEURON. 2022;110(14):2283-2298.e9

Ketamine exerts its sustained antidepressant effects via cell-type-specific regulation of Kcnq2.

Lopez JP; Lücken MD; Brivio E; Karamihalev S; Kos A; De Donno C; Benjamin A; Yang H; Dick ALW; Stoffel R; Flachskamm C; Ressle A; Roeh S; Huettl R-E; Parl A; Eggert C; Novak B; Yan Y; Yeoh K; Holzapfel M; Hauger B; Harbich D; Schmid B; Di Giaimo R; Turck CW; Schmidt MV; Deussing JM; Eder M; Dine J; Theis FJ; Chen A
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):629

Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder.

Lin R; Lopez JP; Cruceanu C; Pierotti C; Fiori LM; Squassina A; Chillotti C; Dieterich C; Mellios N; Turecki G
Journal article: MOLECULAR PSYCHIATRY. 2021;26(8):4191-4204

miR-323a regulates ERBB4 and is involved in depression.

Fiori LM; Kos A; Lin R; Théroux J-F; Lopez JP; Kühne C; Eggert C; Holzapfel M; Huettl R-E; Mechawar N; Belzung C; Ibrahim EC; Chen A; Turecki G
Journal article: MOLECULAR PSYCHIATRY. 2021;26(8):3751-3764

Regulation of impulsive and aggressive behaviours by a novel lncRNA.

Labonté B; Abdallah K; Maussion G; Yerko V; Yang J; Bittar T; Quessy F; Golden SA; Navarro L; Checknita D; Gigek C; Lopez JP; Neve RL; Russo SJ; Tremblay RE; Côté G; Meaney MJ; Mechawar N; Nestler EJ; Turecki G
Journal article: MOLECULAR PSYCHIATRY. 2021;26(7):3060-3076

The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice.

Häusl AS; Brix LM; Hartmann J; Pöhlmann ML; Lopez J-P; Menegaz D; Brivio E; Engelhardt C; Roeh S; Bajaj T; Rudolph L; Stoffel R; Hafner K; Goss HM; Reul JMHM; Deussing JM; Eder M; Ressler KJ; Gassen NC; Chen A; Schmidt MV
Journal article: SCIENCE ADVANCES. 2021;7(5):eabe4497

Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation.

Lopez JP; Brivio E; Santambrogio A; De Donno C; Kos A; Peters M; Rost N; Czamara D; Brückl TM; Roeh S; Pöhlmann ML; Engelhardt C; Ressle A; Stoffel R; Tontsch A; Villamizar JM; Reincke M; Riester A; Sbiera S; Fassnacht M; Mayberg HS; Craighead WE; Dunlop BW; Nemeroff CB; Schmidt MV; Binder EB; Theis FJ; Beuschlein F; Andoniadou CL; Chen A
Journal article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2021;53(2):390-401

Loss of the psychiatric risk factor SLC6A15 is associated with increased metabolic functions in primary hippocampal neurons.

Schraut K-G; Kalnytska O; Lamp D; Jastroch M; Eder M; Hausch F; Gassen NC; Moore S; Nagaraj N; Lopez JP; Chen A; Schmidt MV
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2020;34:39-49

MicroRNA expression profiling of lymphoblasts from bipolar disorder patients who died by suicide, pathway analysis and integration with postmortem brain findings.

Squassina A; Niola P; Lopez JP; Cruceanu C; Pisanu C; Congiu D; Severino G; Ardau R; Chillotti C; Alda M; Turecki G; Del Zompo M
Journal article: NATURE COMMUNICATIONS. 2020;11(1):1635

GPR56/ADGRG1 is associated with response to antidepressant treatment.

Belzeaux R; Gorgievski V; Fiori LM; Lopez JP; Grenier J; Lin R; Nagy C; Ibrahim EC; Gascon E; Courtet P; Richard-Devantoy S; Berlim M; Chachamovich E; Théroux J-F; Dumas S; Giros B; Rotzinger S; Soares CN; Foster JA; Mechawar N; Tall GG; Tzavara ET; Kennedy SH; Turecki G
Journal article: GENES BRAIN AND BEHAVIOR. 2020;19(3):e12643

Sex differences: Transcriptional signatures of stress exposure in male and female brains.

Brivio E; Lopez JP; Chen A
Journal article: JOURNAL OF CLINICAL PSYCHIATRY. 2019;80(3):18m12556

Predicting Worsening Suicidal Ideation With Clinical Features and Peripheral Expression of Messenger RNA and MicroRNA During Antidepressant Treatment.

Belzeaux R; Fiori LM; Lopez JP; Boucekine M; Boyer L; Blier P; Farzan F; Frey BN; Giacobbe P; Lam RW; Leri F; MacQueen GM; Milev R; Müller DJ; Parikh SV; Rotzinger S; Soares CN; Uher R; Foster JA; Kennedy SH; Turecki G
Article: MOLECULAR PSYCHIATRY. 2018;23(10):2050-2056

Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors.

Cruceanu C; Schmouth J-F; Torres-Platas SG; Lopez JP; Ambalavanan A; Darcq E; Gross F; Breton B; Spiegelman D; Rochefort D; Hince P; Petite JM; Gauthier J; Lafrenière RG; Dion PA; Greenwood CM; Kieffer BL; Alda M; Turecki G; Rouleau GA
Journal article: STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS. 2018;21(5):384-388

Preclinical stress research: where are we headed? An early career investigator's perspective.

Gururajan A; Kos A; Lopez JP
Journal article: NATURE MEDICINE. 2018;24(5):591-597

Antidepressive effects of targeting ELK-1 signal transduction.

Apazoglou K; Farley S; Gorgievski V; Belzeaux R; Lopez JP; Grenier J; Ibrahim EC; El Khoury M-A; Tse YC; Mongredien R; Barbé A; de Macedo CEA; Jaworski W; Bochereau A; Orrico A; Isingrini E; Guinaudie C; Mikasova L; Louis F; Gautron S; Groc L; Massaad C; Yildirim F; Vialou V; Dumas S; Marti F; Mechawar N; Morice E; Wong TP; Caboche J; Turecki G; Giros B; Tzavara ET
Journal article: CURRENT OPINION IN PSYCHIATRY. 2018;31(1):7-16

Major depression and its treatment: microRNAs as peripheral biomarkers of diagnosis and treatment response.

Lopez JP; Kos A; Turecki G
Journal article: NEUROPSYCHOPHARMACOLOGY. 2017;42(10):2043-2051

Co-Variation of Peripheral Levels of miR-1202 and Brain Activity and Connectivity During Antidepressant Treatment.

Lopez JP; Pereira F; Richard-Devantoy S; Berlim M; Chachamovich E; Fiori LM; Niola P; Turecki G; Jollant F
Article: JOURNAL OF MOLECULAR NEUROSCIENCE. 2017;62(3-4):304-308

Evidence towards RNA Binding Motif (RNP1, RRM) Protein 3 (RBM3) as a Potential Biomarker of Lithium Response in Bipolar Disorder Patients.

Papadima EM; Niola P; Melis C; Pisanu C; Congiu D; Cruceanu C; Lopez JP; Turecki G; Ardau R; Severino G; Chillotti C; Del Zompo M; Squassina A
Journal article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2017;20(8):619-623

Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response.

Fiori LM; Lopez JP; Richard-Devantoy S; Berlim M; Chachamovich E; Jollant F; Foster J; Rotzinger S; Kennedy SH; Turecki G
Article: NATURE COMMUNICATIONS. 2017;8:15497

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes.

Lopez JP; Fiori LM; Cruceanu C; Lin R; Labonte B; Cates HM; Heller EA; Vialou V; Ku SM; Gerald C; Han M-H; Foster J; Frey BN; Soares CN; Müller DJ; Farzan F; Leri F; MacQueen GM; Feilotter H; Tyryshkin K; Evans KR; Giacobbe P; Blier P; Lam RW; Milev R; Parikh SV; Rotzinger S; Strother SC; Lewis CM; Aitchison KJ; Wittenberg GM; Mechawar N; Nestler EJ; Uher R; Kennedy SH; Turecki G
Journal article: BIOLOGICAL PSYCHIATRY. 2017;81(4):306-315

DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218.

Torres-Berrío A; Lopez JP; Bagot RC; Nouel D; Dal Bo G; Cuesta S; Zhu L; Manitt C; Eng C; Cooper HM; Storch K-F; Turecki G; Nestler EJ; Flores C
Article: BMC PSYCHIATRY. 2016;16(1):286

DNA hypomethylation of Synapsin II CpG islands associates with increased gene expression in bipolar disorder and major depression.

Cruceanu C; Kutsarova E; Chen ES; Checknita DR; Nagy C; Lopez JP; Alda M; Rouleau GA; Turecki G
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2016;26(7):1241-1247

Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients.

Squassina A; Pisanu C; Congiu D; Caria P; Frau D; Niola P; Melis C; Baggiani G; Lopez JP; Cruceanu C; Turecki G; Severino G; Bocchetta A; Vanni R; Chillotti C; Del Zompo M
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2015;172(11):1131-1140

Transcriptome sequencing of the anterior cingulate in bipolar disorder: dysregulation of G protein-coupled receptors.

Cruceanu C; Tan PPC; Rogic S; Lopez JP; Torres-Platas SG; Gigek CO; Alda M; Rouleau GA; Pavlidis P; Turecki G
Article: BMC MEDICAL GENOMICS. 2015;8:35

Biomarker discovery: quantification of microRNAs and other small non-coding RNAs using next generation sequencing.

Lopez JP; Diallo A; Cruceanu C; Fiori LM; Laboissiere S; Guillet I; Fontaine J; Ragoussis J; Benes V; Turecki G; Ernst C
Journal article: TRANSLATIONAL PSYCHIATRY. 2015;5(5):e565

A molecular model for neurodevelopmental disorders.

Gigek CO; Chen ES; Ota VK; Maussion G; Peng H; Vaillancourt K; Diallo AB; Lopez JP; Crapper L; Vasuta C; Chen GG; Ernst C
Article: JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. 2015;74(5):459-469

Effects of postmortem interval on biomolecule integrity in the brain.

Nagy C; Maheu M; Lopez JP; Vaillancourt K; Cruceanu C; Gross JA; Arnovitz M; Mechawar N; Turecki G
Journal article: TRANSLATIONAL PSYCHIATRY. 2015;5(2):e511

MicroRNA regulation of central glial cell line-derived neurotrophic factor (GDNF) signalling in depression.

Maheu M; Lopez JP; Crapper L; Davoli MA; Turecki G; Mechawar N
Journal article: PSYCHIATRY RESEARCH. 2014;220(3):1167-1168

Lithium-induced differential expression of SAT1 in suicide completers and controls is not correlated with polymorphisms in the promoter region of the gene.

Niola P; Gross JA; Lopez JP; Chillotti C; Deiana V; Manchia M; Georgitsi M; Patrinos GP; Alda M; Turecki G; Del Zompo M; Squassina A
Journal article: AMERICAN JOURNAL OF HUMAN GENETICS. 2014;95(5):490-508

Molecular convergence of neurodevelopmental disorders.

Chen ES; Gigek CO; Rosenfeld JA; Diallo AB; Maussion G; Chen GG; Vaillancourt K; Lopez JP; Crapper L; Poujol R; Shaffer LG; Bourque G; Ernst C
Article: NATURE MEDICINE. 2014;20(7):764-768

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment.

Lopez JP; Lim R; Cruceanu C; Crapper L; Fasano C; Labonte B; Maussion G; Yang JP; Yerko V; Vigneault E; El Mestikawy S; Mechawar N; Pavlidis P; Turecki G
Journal article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2014;17(1):23-32

Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers.

Lopez JP; Fiori LM; Gross JA; Labonte B; Yerko V; Mechawar N; Turecki G
Journal article: TRANSLATIONAL PSYCHIATRY. 2013;3(12):e338

dcc orchestrates the development of the prefrontal cortex during adolescence and is altered in psychiatric patients.

Manitt C; Eng C; Pokinko M; Ryan RT; Torres-Berrío A; Lopez JP; Yogendran SV; Daubaras MJJ; Grant A; Schmidt ERE; Tronche F; Krimpenfort P; Cooper HM; Pasterkamp RJ; Kolb B; Turecki G; Wong TP; Nestler EJ; Giros B; Flores C
Journal article: AMERICAN JOURNAL OF PSYCHIATRY. 2013;170(5):511-520

Genome-wide methylation changes in the brains of suicide completers.

Labonté B; Suderman M; Maussion G; Lopez JP; Navarro-Sánchez L; Yerko V; Mechawar N; Szyf M; Meaney MJ; Turecki G
Journal article: MOLECULAR PSYCHIATRY. 2013;18(4):398-399

Epigenetic regulation of BDNF expression according to antidepressant response.

Lopez JP; Mamdani F; Labonte B; Beaulieu M-M; Yang JP; Berlim MT; Ernst C; Turecki G
Journal article: JOURNAL OF PSYCHIATRIC RESEARCH. 2013;47(4):513-519

Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide.

Gross JA; Fiori LM; Labonté B; Lopez JP; Turecki G
Journal article: AMERICAN JOURNAL OF HUMAN GENETICS. 2012;91(6):1128-1134

Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities.

Talkowski ME; Maussion G; Crapper L; Rosenfeld JA; Blumenthal I; Hanscom C; Chiang C; Lindgren A; Pereira S; Ruderfer D; Diallo AB; Lopez JP; Turecki G; Chen ES; Gigek C; Harris DJ; Lip V; An Y; Biagioli M; Macdonald ME; Lin M; Haggarty SJ; Sklar P; Purcell S; Kellis M; Schwartz S; Shaffer LG; Natowicz MR; Shen Y; Morton CC; Gusella JF; Ernst C
Journal article: JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING. 2011;31(2):87-92

A New System and Paradigm for Chronic Stimulation of Denervated Rat Muscle.

Willand MP; Lopez JP; de Bruin H; Fahnestock M; Holmes M; Bain JR
Journal article: ANIMAL COGNITION. 2009;12(4):559-565

Bobwhite quail (Colinus virginianus) hatchlings track the direction of human gaze.

Jaime M; Lopez JP; Lickliter R
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Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S536

MicroRNAs as biomarkers of antidepressant treatment response

Lopez JP; Turecki G
Letter: MOLECULAR PSYCHIATRY. 2017;22(9):1228-1229

Dysregulation of the glutamatergic receptors after antidepressant treatment in human neural progenitor cells.

Cruceanu C; Lopez JP; Tsai W-T; Turecki G
Conference publication: EUROPEAN PSYCHIATRY. 2017;41:S167

Peripheral levels of the micro-RNA miR-1202 are correlated with changes in brain activity and connectivity during an antidepressant treatment

Lopez JP; Pereira F; Richard-Devantoy S; Ding Y; Fiori LM; Niola P; Turecki G; Jollant F
Conference publication: NEUROPSYCHOPHARMACOLOGY. 2016;41:S10-S11

Small Non-Coding RNA Targets of Antidepressant Treatment

Lopez JP
Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2016;19:11-12

Regulation of aggressive and impulsive behaviours by a novel lincRNA

Turecki G; Labonte B; Maussion G; Yerko V; Yang J; Golden SA; Suderman M; Navarro L; Checknita D; Gigek C; Lopez JP; Neve R; Russo SJ; Cote G; Meaney MJ; Mechawar N; Nestler EJ
Conference publication: BIOLOGICAL PSYCHIATRY. 2015;77(9):59S

Relative Expression of GDNF Family Receptor Alpha 1 (GFRA1) Isoforms Regulates GDNF Signaling: Implications for Depression

Maheu M; Lopez JP; Crapper L; Davoli MA; Turecki G; Mechawar N
Conference publication: BIOLOGICAL PSYCHIATRY. 2013;73(9):224S

A Primate-Specific and Brain-Enriched miRNA is Involved in Depression and Regulates the Expression of GRM4

Lopez JP; Lim R; Ernst C; Naguib M; Pavlidis P; Turecki G
Conference publication: BIOLOGICAL PSYCHIATRY. 2012;71(8):46S

GDNF Family Receptor Alpha-1 (GFRa1) Expression and Regulation in the Basolateral Amygdala of Depressed Suicides

Maheu M; Lopez JP; Davoli MA; Turecki G; Mechawar N
Conference publication: GENOME. 2012;55(10):725

Rare susceptibility variants for familial bipolar disorder: an exome-sequencing study

Cruceanu C; Gauthier J; Ambalavanan A; Lopez JP; Spiegelman D; Lafreniere RG; Grof P; Alda M; Turecki G; Rouleau GA
Conference publication: BIOLOGICAL PSYCHIATRY. 2011;69(9):132S

The Potential Regulatory Role of miRNAs in Polyamine Gene Expression in the Prefrontal Cortex of Suicide Completers

Lopez JP; Cruceanu C; Fiori LM; Yerko V; Turecki G

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