Johan Fastbom

Om mig
Publikationer
CV
Populärvetenskap och samverkan

Om mig

Johan Fastbom är professor i geriatrisk farmakologi vid Karolinska Institutet sedan 2011. Hans forskning syftar till att förbättra kvaliteten i äldres läkemedelsanvändning.

Artiklar

Article: EUROPEAN HEART JOURNAL. 2023;44(7):573-582

Cardiometabolic multimorbidity and incident dementia: the Swedish twin registry.

Dove A; Guo J; Marseglia A; Fastbom J; Vetrano DL; Fratiglioni L; Pedersen NL; Xu W
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2023;51(1):11-20

Socio-demographic differences in polypharmacy and potentially inappropriate drug use among older people with different care needs and in care settings in Stockholm, Sweden.

Doheny M; Schön P; Orsini N; Fastbom J; Burström B; Agerholm J
Article: FRONTIERS IN PHARMACOLOGY. 2023;14:1030849

Regional variations in excessive polypharmacy and potentially inappropriate drug use among older adults in Sweden: Trends from 2006 to 2020.

Wastesson JW; Fritzell J; Burström B; Johnell K; Fastbom J
Article: JAMA NETWORK OPEN. 2022;5(10):e2236757

Performance of 3 Sets of Criteria for Potentially Inappropriate Prescribing in Older People to Identify Inadequate Drug Treatment.

Wallerstedt SM; Svensson SA; Lönnbro J; Hieronymus F; Fastbom J; Hoffmann M; Parodi López N
Article: ORAL DISEASES. 2022;28(6):1697-1704

Validating a model for medication-related dental outcomes in older people.

Tan ECK; Lexomboon D; Häbel H; Fastbom J; Eriksdotter M; Johnell K; Sandborgh-Englund G
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2022;78(9):1459-1467

Prevalence and initiation of statin therapy in the oldest old-a longitudinal population-based study.

Sundvall H; Vitols S; Wallerstedt SM; Fastbom J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2022;37(3):10.1002/gps.5684

Psychoactive medication use and risk of suicide in long-term care facility residents.

Hedna K; Fastbom J; Jonson M; Wilhelmson K; Waern M
Article: PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT. 2021;22:e45

District nurses' experiences of using a clinical decision support system and an assessment tool at elderly care units in primary health care: a qualitative study.

Lagerin A; Törnkvist L; Fastbom J; Lundh L
Article: FRONTIERS IN PUBLIC HEALTH. 2021;9:611559

Antidepressant Use and Suicide Rates in Adults Aged 75 and Above: A Swedish Nationwide Cohort Study.

Hedna K; Fastbom J; Erlangsen A; Waern M
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2020;75(12):2441-2449

Predictors of Olfactory Decline in Aging: A Longitudinal Population-Based Study.

Ekström I; Larsson M; Rizzuto D; Fastbom J; Bäckman L; Laukka EJ
Article: SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH. 2020;46(6):589-598

Psychosocial job strain and polypharmacy: a national cohort study.

Tan EC; Pan K-Y; Magnusson Hanson LL; Fastbom J; Westerlund H; Wang H-X
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2020;30(5):958-964

Sociodemographic and gender determinants of late-life suicide in users and non-users of antidepressants.

Hedna K; Hensing G; Skoog I; Fastbom J; Waern M
Article: BMC PUBLIC HEALTH. 2020;20(1):764

What are the sociodemographic and gender determinants of non-fatal self-harm in older adult users and non-users of antidepressants? A national population-based study.

Hedna K; Fastbom J; Skoog I; Hensing G; Waern M
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;75(4):1263-1271

Xerogenic Medications as a Predictor for Dental Health Intervention in People with Dementia.

Tan ECK; Lexomboon D; Häbel H; Fastbom J; Eriksdotter M; Johnell K; Sandborgh-Englund G
Article: PRIMARY HEALTH CARE RESEARCH AND DEVELOPMENT. 2020;21:e15

District nurses' use of a decision support and assessment tool to improve the quality and safety of medication use in older adults: a feasibility study.

Lagerin A; Lundh L; Törnkvist L; Fastbom J
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2020;48(3):308-315

Extent and quality of drug use in community-dwelling people aged ≥75 years: A Swedish nationwide register-based study.

Lagerin A; Törnkvist L; Nilsson G; Johnell K; Fastbom J
Article: BMJ OPEN. 2020;10(3):e034560

Drug use and torsades de pointes cardiac arrhythmias in Sweden: a nationwide register-based cohort study.

Danielsson B; Collin J; Nyman A; Bergendal A; Borg N; State M; Bergfeldt L; Fastbom J
Article: BMC GERIATRICS. 2020;20(1):73

Use of potentially inappropriate medication and polypharmacy in older adults: a repeated cross-sectional study.

Thorell K; Midlöv P; Fastbom J; Halling A
Article: JOURNAL OF ALZHEIMERS DISEASE. 2020;73(3):1013-1021

Secondary Stroke Prevention After Ischemic Stroke in Patients with Alzheimer's Disease and Other Dementia Disorders.

Zupanic E; Kramberger MG; von Euler M; Norrving B; Winblad B; Secnik J; Fastbom J; Eriksdotter M; Garcia-Ptacek S
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2020;86:103960

Factors associated with emergency department revisits among older adults in two Swedish regions: A prospective cohort study.

Naseer M; Agerholm J; Fastbom J; Schön P; Ehrenberg A; Dahlberg L
Article: BMJ OPEN DIABETES RESEARCH & CARE. 2020;8(1):e000833

Cholinesterase inhibitors in patients with diabetes mellitus and dementia: an open-cohort study of ~23 000 patients from the Swedish Dementia Registry.

Secnik J; Schwertner E; Alvarsson M; Hammar N; Fastbom J; Winblad B; Garcia-Ptacek S; Religa D; Eriksdotter M
Article: AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY. 2020;28(1):108-117

Do Acetylcholinesterase Inhibitors Prevent or Delay Psychotropic Prescribing in People With Dementia? Analyses of the Swedish Dementia Registry.

Tan ECK; Johnell K; Bell JS; Garcia-Ptacek S; Fastbom J; Nordström P; Eriksdotter M
Article: BMJ OPEN. 2019;9(9):e029477

Importance of potentially inappropriate medications, number of chronic conditions and medications for the risk of hospitalisation in elderly in Sweden: a case-control study.

Thorell K; Midlöv P; Fastbom J; Halling A
Article: PALLIATIVE MEDICINE. 2019;33(8):1080-1090

How many older adults receive drugs of questionable clinical benefit near the end of life? A cohort study.

Morin L; Wastesson JW; Laroche M-L; Fastbom J; Johnell K
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2019;75(7):959-967

Use of statins in the elderly according to age and indication-a cross-sectional population-based register study.

Sundvall H; Fastbom J; Wallerstedt SM; Vitols S
Article: CANCER. 2019;125(13):2309-2317

Preventive drugs in the last year of life of older adults with cancer: Is there room for deprescribing?

Morin L; Todd A; Barclay S; Wastesson JW; Fastbom J; Johnell K
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(12):1080-1085.e2

The Effect of Xerostomic Medication on Oral Health in Persons With Dementia.

Lexomboon D; Tan EC; Höijer J; Garcia-Ptacek S; Eriksdotter M; Religa D; Fastbom J; Johnell K; Sandborgh-Englund G
Article: NEUROLOGY. 2018;91(19):e1732-e1740

Atrial fibrillation, antithrombotic treatment, and cognitive aging: A population-based study.

Ding M; Fratiglioni L; Johnell K; Santoni G; Fastbom J; Ljungman P; Marengoni A; Qiu C
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2018;74(10):1333-1342

Adequate, questionable, and inadequate drug prescribing for older adults at the end of life: a European expert consensus.

Morin L; Laroche M-L; Vetrano DL; Fastbom J; Johnell K
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;65(2):589-596

Anticholinergic Burden and Risk of Stroke and Death in People with Different Types of Dementia.

Tan ECK; Eriksdotter M; Garcia-Ptacek S; Fastbom J; Johnell K
Article: ALZHEIMERS & DEMENTIA. 2018;14(7):944-951

Acetylcholinesterase inhibitors and risk of stroke and death in people with dementia.

Tan ECK; Johnell K; Garcia-Ptacek S; Haaksma ML; Fastbom J; Bell JS; Eriksdotter M
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(7):577-583

Antihypertensive Medication Regimen Intensity and Incident Dementia in an Older Population.

Tan ECK; Qiu C; Liang Y; Wang R; Bell JS; Fastbom J; Fratiglioni L; Johnell K
Article: DRUGS & AGING. 2018;35(3):243-248

Prescription Changes During Geriatric Care Episodes: A Trend Analysis Conducted in Sweden.

Reimers M; Eriksdotter M; Seiger Å; Fastbom J
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2018;19(3):193-199

Research Priorities for Optimizing Geriatric Pharmacotherapy: An International Consensus.

Tan ECK; Sluggett JK; Johnell K; Onder G; Elseviers M; Morin L; Vetrano DL; Wastesson JW; Fastbom J; Taipale H; Tanskanen A; Bell JS; Optimizing Geriatric Pharmacotherapy through Pharm
Article: JOURNAL OF ALZHEIMERS DISEASE. 2018;61(3):1119-1128

Treatment of Atrial Fibrillation in Patients with Dementia: A Cohort Study from the Swedish Dementia Registry.

Subic A; Cermakova P; Religa D; Han S; von Euler M; Kåreholt I; Johnell K; Fastbom J; Bognandi L; Winblad B; Kramberger MG; Eriksdotter M; Garcia-Ptacek S
Article: CLINICAL EPIDEMIOLOGY. 2018;10:289-298

The epidemiology of polypharmacy in older adults: register-based prospective cohort study.

Morin L; Johnell K; Laroche M-L; Fastbom J; Wastesson JW
Article: PLOS ONE. 2018;13(3):e0194892

The composition of polypharmacy: A register-based study of Swedes aged 75 years and older.

Wastesson JW; Cedazo Minguez A; Fastbom J; Maioli S; Johnell K
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2017;249:173-178

Atrial fibrillation and use of antithrombotic medications in older people: A population-based study.

Ding M; Fratiglioni L; Johnell K; Fastbom J; Ljungdahl M; Qiu C
Article: NEUROLOGY. 2017;89(18):1860-1868

Thrombolysis in acute ischemic stroke in patients with dementia: A Swedish registry study.

Zupanic E; von Euler M; Kåreholt I; Contreras Escamez B; Fastbom J; Norrving B; Religa D; Kramberger MG; Winblad B; Johnell K; Eriksdotter M; Garcia-Ptacek S
Article: DIABETES CARE. 2017;40(9):1159-1166

Diabetes in a Large Dementia Cohort: Clinical Characteristics and Treatment From the Swedish Dementia Registry.

Secnik J; Cermakova P; Fereshtehnejad S-M; Dannberg P; Johnell K; Fastbom J; Winblad B; Eriksdotter M; Religa D
Article: AMERICAN JOURNAL OF MEDICINE. 2017;130(8):927-936.e9

Choosing Wisely? Measuring the Burden of Medications in Older Adults near the End of Life: Nationwide, Longitudinal Cohort Study.

Morin L; Vetrano DL; Rizzuto D; Calderón-Larrañaga A; Fastbom J; Johnell K
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2017;35(3):271-278

Pay for performance associated with increased volume of medication reviews but not with less inappropriate use of medications among the elderly - an observational study.

Ödesjö H; Anell A; Boman A; Fastbom J; Franzén S; Thorn J; Björck S
Article: NEUROBIOLOGY OF AGING. 2017;55:27-32

Anticholinergic drug use is associated with episodic memory decline in older adults without dementia.

Papenberg G; Bäckman L; Fratiglioni L; Laukka EJ; Fastbom J; Johnell K
Article: DRUGS & AGING. 2017;34(7):529-533

Drug Use in Older Adults with Amyotrophic Lateral Sclerosis Near the End of Life.

Grande G; Morin L; Vetrano DL; Fastbom J; Johnell K
Article: JOURNAL OF ALZHEIMERS DISEASE. 2017;58(4):1265-1272

Living Alone with Alzheimer's Disease: Data from SveDem, the Swedish Dementia Registry.

Cermakova P; Nelson M; Secnik J; Garcia-Ptacek S; Johnell K; Fastbom J; Kilander L; Winblad B; Eriksdotter M; Religa D
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2017;18(6):551.e1-551.e7

Use of Medications of Questionable Benefit During the Last Year of Life of Older Adults With Dementia.

Morin L; Vetrano DL; Grande G; Fratiglioni L; Fastbom J; Johnell K
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(6):675-684

Cognitive performance in unipolar old-age depression: a longitudinal study.

Pantzar A; Atti AR; Fratiglioni L; Fastbom J; Bäckman L; Laukka EJ
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2017;32(4):414-420

Psychotropic drugs and the risk of fall injuries, hospitalisations and mortality among older adults.

Johnell K; Jonasdottir Bergman G; Fastbom J; Danielsson B; Borg N; Salmi P
Article: JOURNAL OF NURSING MANAGEMENT. 2017;25(1):56-64

Nurses' use of computerised decision support systems affects drug monitoring in nursing homes.

Johansson-Pajala R-M; Gustafsson L-K; Jorsäter Blomgren K; Fastbom J; Martin L
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2017;26(1):9-16

Long-term use of proton pump inhibitors and prevalence of disease- and drug-related reasons for gastroprotection-a cross-sectional population-based study.

Wallerstedt SM; Fastbom J; Linke J; Vitols S
Article: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2017;18(1):19-23

Management of Acute Myocardial Infarction in Patients With Dementia: Data From SveDem, the Swedish Dementia Registry.

Cermakova P; Szummer K; Johnell K; Fastbom J; Winblad B; Eriksdotter M; Religa D
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2016;134(5):430-440

Antidepressants and mortality risk in a dementia cohort: data from SveDem, the Swedish Dementia Registry.

Enache D; Fereshtehnejad S-M; Kåreholt I; Cermakova P; Garcia-Ptacek S; Johnell K; Religa D; Jelic V; Winblad B; Ballard C; Aarsland D; Fastbom J; Eriksdotter M
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2016;64(9):1851-1857

Aggressiveness of End-of-Life Care for Hospitalized Individuals with Cancer with and without Dementia: A Nationwide Matched-Cohort Study in France.

Morin L; Beaussant Y; Aubry R; Fastbom J; Johnell K
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2016;71(6):831-837

Medication Regimen Complexity and Number of Medications as Factors Associated With Unplanned Hospitalizations in Older People: A Population-based Cohort Study.

Wimmer BC; Bell JS; Fastbom J; Wiese MD; Johnell K
Article: PARKINSONISM & RELATED DISORDERS. 2016;27:85-88

Use of antidepressants in Parkinson's disease: A Swedish register-based study of over 1.5 million older people.

Haasum Y; Fastbom J; Johnell K
Article: EUROPEAN JOURNAL OF INTERNAL MEDICINE. 2016;31:29-34

Coexisting chronic conditions in the older population: Variation by health indicators.

Marengoni A; Angleman S; Meinow B; Santoni G; Mangialasche F; Rizzuto D; Fastbom J; Melis R; Parker M; Johnell K; Fratiglioni L
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2016;81(4):773-783

Antidepressants and antipsychotics classified with torsades de pointes arrhythmia risk and mortality in older adults - a Swedish nationwide study.

Danielsson B; Collin J; Jonasdottir Bergman G; Borg N; Salmi P; Fastbom J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2016;52(1):213-222

Influence of Incipient Dementia on Hospitalization for Primary Care Sensitive Conditions: A Population-Based Cohort Study.

Pimouguet C; Rizzuto D; Fastbom J; Lagergren M; Fratiglioni L; Xu W
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2016;63:28-35

Time trends in 20 years of medication use in older adults: Findings from three elderly cohorts in Stockholm, Sweden.

Craftman ÅG; Johnell K; Fastbom J; Westerbotn M; von Strauss E
Article: BMC NEUROLOGY. 2016;16:28

The impact of dementia on drug costs in older people: results from the SNAC study.

Sköldunger A; Fastbom J; Wimo A; Fratiglioni L; Johnell K
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2016;71(2):188-195

Telomerase Gene (hTERT) and Survival: Results From Two Swedish Cohorts of Older Adults.

Kalpouzos G; Rizzuto D; Keller L; Fastbom J; Santoni G; Angleman S; Graff C; Bäckman L; Fratiglioni L
Article: ANNALS OF PHARMACOTHERAPY. 2016;50(2):89-95

Medication Regimen Complexity and Polypharmacy as Factors Associated With All-Cause Mortality in Older People: A Population-Based Cohort Study.

Wimmer BC; Bell JS; Fastbom J; Wiese MD; Johnell K
Article: ALZHEIMERS & DEMENTIA. 2016;12(2):100-109

Prudent diet may attenuate the adverse effects of Western diet on cognitive decline.

Shakersain B; Santoni G; Larsson SC; Faxén-Irving G; Fastbom J; Fratiglioni L; Xu W
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2016;34(1):37-45

Nurses in municipal care of the elderly act as pharmacovigilant intermediaries: a qualitative study of medication management.

Johansson-Pajala R-M; Jorsäter Blomgren K; Bastholm-Rahmner P; Fastbom J; Martin L
Article: PLOS ONE. 2016;11(8):e0161246

Use of Fall-Risk Inducing Drugs in Patients Using Anti-Parkinson Drugs (APD): A Swedish Register-Based Study.

Haasum Y; Fastbom J; Johnell K
Article: BRITISH JOURNAL OF PSYCHIATRY. 2015;207(5):444-449

Incidence of antipsychotic use in relation to diagnosis of Alzheimer's disease among community-dwelling persons.

Koponen M; Tolppanen A-M; Taipale H; Tanskanen A; Tiihonen J; Johnell K; Fastbom J; Ahonen R; Hartikainen S
Article: JOURNAL OF ALZHEIMERS DISEASE. 2015;48(4):949-958

Cardiovascular Diseases in ~30,000 Patients in the Swedish Dementia Registry.

Cermakova P; Johnell K; Fastbom J; Garcia-Ptacek S; Lund LH; Winblad B; Eriksdotter M; Religa D
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2015;24(9):906-914

Association between drug-specific indicators of prescribing quality and quality of drug treatment: a validation study.

Wallerstedt SM; Belfrage B; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2015;71(9):1099-1108

Factors associated with medication regimen complexity in older people: a cross-sectional population-based study.

Wimmer BC; Johnell K; Fastbom J; Wiese MD; Bell JS
Article: DRUGS & AGING. 2015;32(8):671-678

Impact of Inappropriate Drug Use on Hospitalizations, Mortality, and Costs in Older Persons and Persons with Dementia: Findings from the SNAC Study.

Sköldunger A; Fastbom J; Wimo A; Fratiglioni L; Johnell K
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2015;80(2):315-324

Potentially inappropriate drug use in older people: a nationwide comparison of different explicit criteria for population-based estimates.

Morin L; Fastbom J; Laroche M-L; Johnell K
Article: JOURNAL OF EVALUATION IN CLINICAL PRACTICE. 2015;21(1):145-152

Nurses' self-reported medication competence in relation to their pharmacovigilant activities in clinical practice.

Johansson-Pajala R-M; Martin L; Fastbom J; Jorsäter Blomgren K
Article: EUROPEAN JOURNAL OF PUBLIC HEALTH. 2014;24(6):991-996

Socioeconomic inequalities in access to specialized psychotropic prescribing among older Swedes: a register-based study.

Wastesson JW; Fastbom J; Ringbäck Weitoft G; Fors S; Johnell K
Article: PSYCHOLOGICAL MEDICINE. 2014;44(5):937-947

Cognitive deficits in unipolar old-age depression: a population-based study.

Pantzar A; Laukka EJ; Atti AR; Fastbom J; Fratiglioni L; Bäckman L
Article: DRUGS & AGING. 2014;31(3):225-232

Prevalence and impact of fall-risk-increasing drugs, polypharmacy, and drug-drug interactions in robust versus frail hospitalised falls patients: a prospective cohort study.

Bennett A; Gnjidic D; Gillett M; Carroll P; Matthews S; Johnell K; Fastbom J; Hilmer S
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2013;69(3):665-671

Different patterns in use of antibiotics for lower urinary tract infection in institutionalized and home-dwelling elderly: a register-based study.

Haasum Y; Fastbom J; Johnell K
Article: PLOS ONE. 2013;8(6):e67088

Drug treatment in older people before and after the transition to a multi-dose drug dispensing system--a longitudinal analysis.

Wallerstedt SM; Fastbom J; Johnell K; Sjöberg C; Landahl S; Sundström A
Article: SCANDINAVIAN JOURNAL OF PUBLIC HEALTH. 2012;40(9 Suppl):293-304

Prescription drugs: Health in Sweden: The National Public Health Report 2012. Chapter 18.

Weitoft GR; Ericsson O; Fastbom J
Article: DRUGS & AGING. 2012;29(9):751-758

Comparison of prescription drug use between community-dwelling and institutionalized elderly in Sweden.

Johnell K; Fastbom J
Article: OSTEOPOROSIS INTERNATIONAL. 2012;23(3):1061-1068

Undertreatment of osteoporosis in persons with dementia? A population-based study.

Haasum Y; Fastbom J; Fratiglioni L; Johnell K
Article: ANNALS OF PHARMACOTHERAPY. 2012;46(3):339-346

Institutionalization as a risk factor for inappropriate drug use in the elderly: a Swedish nationwide register-based study.

Haasum Y; Fastbom J; Johnell K
Article: AGE AND AGEING. 2012;41(2):218-224

Drug use in centenarians compared with nonagenarians and octogenarians in Sweden: a nationwide register-based study.

Wastesson JW; Parker MG; Fastbom J; Thorslund M; Johnell K
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2011;67(10):1069-1075

Antiepileptic drug use in community-dwelling and institutionalized elderly: a nationwide study of over 1,300,000 older people.

Johnell K; Fastbom J
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACY. 2011;33(5):788-793

Gender and use of hypnotics or sedatives in old age: a nationwide register-based study.

Johnell K; Fastbom J
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2011;29(3):181-186

Dementia management programme in a community setting and the use of psychotropic drugs in the elderly population.

Jedenius E; Johnell K; Fastbom J; Strömqvist J; Winblad B; Andreasen N
Article: DRUGS & AGING. 2011;28(4):283-293

Pain treatment in elderly persons with and without dementia: a population-based study of institutionalized and home-dwelling elderly.

Haasum Y; Fastbom J; Fratiglioni L; Kåreholt I; Johnell K
Article: PLOS ONE. 2011;6(10):e26574

Association between multi-dose drug dispensing and quality of drug treatment--a register-based study.

Sjöberg C; Edward C; Fastbom J; Johnell K; Landahl S; Narbro K; Wallerstedt SM
Article: INTERNATIONAL JOURNAL OF HEALTH CARE QUALITY ASSURANCE. 2010;23(6):571-582

Medication reviews with computerised expert support: evaluation of a method to improve the quality of drug utilisation in the elderly.

Ulfvarson J; Rahmner PB; Fastbom J; Sjöviker S; Karlsson EA
Article: CLINICAL DRUG INVESTIGATION. 2010;30(5):289-300

Quality of drug prescribing in elderly people in nursing homes and special care units for dementia: a cross-sectional computerized pharmacy register analysis.

Olsson J; Bergman A; Carlsten A; Oké T; Bernsten C; Schmidt IK; Fastbom J
Article: ARCHIVES OF OSTEOPOROSIS. 2009;4(1-2):17-23

Undertreatment of osteoporosis in the oldest old? A nationwide study of over 700,000 older people.

Johnell K; Fastbom J
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2009;24(7):731-738

The use of benzodiazpines and related drugs amongst older people in Sweden: associated factors and concomitant use of other psychotropics.

Johnell K; Fastbom J
Article: ANNALS OF PHARMACOTHERAPY. 2009;43(7):1233-1238

Sex differences in inappropriate drug use: a register-based study of over 600,000 older people.

Johnell K; Weitoft GR; Fastbom J
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2009;57(1):62-69

The influence of educational level on polypharmacy and inappropriate drug use: a register-based study of more than 600,000 older people.

Haider SI; Johnell K; Weitoft GR; Thorslund M; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(12):1215-1222

Patient educational level and use of newly marketed drugs: a register-based study of over 600,000 older people.

Haider SI; Johnell K; Ringbäck Weitoft G; Thorslund M; Fastbom J
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2008;64(11):1119-1124

The association between use of cardiovascular drugs and antidepressants: a nationwide register-based study.

Johnell K; Fastbom J
Article: JOURNAL OF CLINICAL NURSING. 2008;17(5A):106-115

How do older people experience their management of medicines?

Westerbotn M; Fahlström E; Fastbom J; Agüero-Torres H; Hillerås P
Article: AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2008;20(1):40-46

Pain reporting by very old Swedish community dwellers: the role of cognition and function.

Westerbotn M; Hillerås P; Fastbom J; Agüero-Torres H
Article: CLINICAL THERAPEUTICS. 2008;30(2):419-427

Analysis of the association between polypharmacy and socioeconomic position among elderly aged > or =77 years in Sweden.

Haider SI; Johnell K; Thorslund M; Fastbom J
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2008;26(2):86-91

Multi-dose drug dispensing and inappropriate drug use: A nationwide register-based study of over 700,000 elderly.

Johnell K; Fastbom J
Article: CLINICAL DRUG INVESTIGATION. 2008;28(11):687-695

Concomitant use of gastroprotective drugs among elderly NSAID/COX-2 selective inhibitor users: a nationwide register-based study.

Johnell K; Fastbom J
Article: DRUGS & AGING. 2008;25(10):871-877

Concurrent use of anticholinergic drugs and cholinesterase inhibitors: register-based study of over 700,000 elderly patients.

Johnell K; Fastbom J
Article: DEMENTIA AND GERIATRIC COGNITIVE DISORDERS. 2008;25(1):54-59

Education and use of dementia drugs: a register-based study of over 600,000 older people.

Johnell K; Weitoft GR; Fastbom J
Article: INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS. 2007;45(12):643-653

Trends in polypharmacy and potential drug-drug interactions across educational groups in elderly patients in Sweden for the period 1992 - 2002.

Haider SI; Johnell K; Thorslund M; Fastbom J
Article: ANNALS OF PHARMACOTHERAPY. 2007;41(7):1243-1248

Inappropriate drug use in the elderly: a nationwide register-based study.

Johnell K; Fastbom J; Rosén M; Leimanis A
Article: SCANDINAVIAN JOURNAL OF PRIMARY HEALTH CARE. 2007;25(1):9-14

Evaluation of the quality of drug therapy among elderly patients in nursing homes.

Bergman A; Olsson J; Carlsten A; Waern M; Fastbom J
Article: AGING CLINICAL AND EXPERIMENTAL RESEARCH. 2006;18(6):497-502

Factors influencing the handling of medicines among very old people living at home in an urban area.

Westerbotn M; Hillerås P; Fastbom J; Agüero-Torres H
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2006;62(7):555-562

The use of angiotensin-converting enzyme inhibitors and other drugs with cardiovascular effects by non-demented and demented elderly with a clinical diagnosis of heart failure. A population-based study of the very old.

Klarin I; Fastbom J; Wimo A
Article: ARCHIVES OF INTERNAL MEDICINE (CHICAGO, ILL. : 1908). 2006;166(9):1003-1008

Heart failure and risk of dementia and Alzheimer disease: a population-based cohort study.

Qiu C; Winblad B; Marengoni A; Klarin I; Fastbom J; Fratiglioni L
Article: PHARMACY WORLD AND SCIENCE. 2005;27(5):393-398

The difficulty of opening medicine containers in old age: a population-based study.

Beckman A; Bernsten C; Parker MG; Thorslund M; Fastbom J
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2005;40(3):287-297

A population-based study on well-being in the very old: the role of cardiovascular diseases and drugs.

Westerbotn M; Agüero-Torres H; Fastbom J; Hillerås P
Article: DRUGS & AGING. 2005;22(1):69-82

The association of inappropriate drug use with hospitalisation and mortality: a population-based study of the very old.

Klarin I; Wimo A; Fastbom J
Article: LAKARTIDNINGEN. 2004;101(46):3683-3688

[Shortages in the treatment of depression of the elderly in nursing homes in Stockholm. Diagnosis is based on flimsy ground, follow up performed early].

Fastbom J; Schmidt I
Article: NEUROEPIDEMIOLOGY. 2004;23(3):135-143

Aspirin, NSAIDs, risk of dementia, and influence of the apolipoprotein E epsilon 4 allele in an elderly population.

Cornelius C; Fastbom J; Winblad B; Viitanen M
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2004;60(2):121-126

Drug use and increased HbA1c levels in non-diabetic very elderly persons: the Kungsholmen project.

Passare G; Fastbom J; Törring O; Viitanen M
Article: CLINICAL DRUG INVESTIGATION. 2004;24(9):535-544

Sodium and potassium disturbances in the elderly : prevalence and association with drug use.

Passare G; Viitanen M; Törring O; Winblad B; Fastbom J
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2004;8(1):127-134

Beta-secretase-cleaved amyloid precursor protein in Alzheimer brain: a morphologic study.

Sennvik K; Bogdanovic N; Volkmann I; Fastbom J; Benedikz E
Article: PHARMACOEPIDEMIOLOGY AND DRUG SAFETY. 2003;12(8):669-678

A population-based study of drug use in the very old living in a rural district of Sweden, with focus on cardiovascular drug consumption: comparison with an urban cohort.

Klarin I; Fastbom J; Wimo A
Article: NEUROLOGY. 2003;61(5):655-660

Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD.

Qiu C; Winblad B; Fastbom J; Fratiglioni L
Article: NEUROREPORT. 2003;14(11):1523-1527

G-protein alpha-subunit levels in hippocampus and entorhinal cortex of brains staged for Alzheimer's disease neurofibrillary and amyloid pathologies.

García-Jiménez A; Fastbom J; Ohm TG; Cowburn RF
Article: ARCHIVES OF NEUROLOGY. 2003;60(2):223-228

Low blood pressure and risk of dementia in the Kungsholmen project: a 6-year follow-up study.

Qiu C; von Strauss E; Fastbom J; Winblad B; Fratiglioni L
Article: ANNALS OF PHARMACOTHERAPY. 2002;36(11):1675-1681

Drug-drug interactions in the elderly.

Björkman IK; Fastbom J; Schmidt IK; Bernsten CB; Pharmaceutical Care of the Elderly in Europe Resea
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 2002;35(2):95-105

Cognitive functioning in a population-based sample of very old non-demented and non-depressed persons: the impact of diabetes.

Nilsson E; Fastbom J; Wahlin A
Article: NEUROPSYCHOLOGY. 2002;16(2):208-216

Cognitive performance in very old diabetic persons: the impact of semantic structure, preclinical dementia, and impending death.

Wahlin A; Nilsson E; Fastbom J
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2002;57(4):M236-M240

Sleep problems in a very old population: drug use and clinical correlates.

Giron MST; Forsell Y; Bernsten C; Thorslund M; Winblad B; Fastbom J
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2002;67(3):388-398

Loss of stimulatory effect of guanosine triphosphate on [(35)S]GTPgammaS binding correlates with Alzheimer's disease neurofibrillary pathology in entorhinal cortex and CA1 hippocampal subfield.

García-Jiménez A; Cowburn RF; Ohm TG; Lasn H; Winblad B; Bogdanovic N; Fastbom J
Article: BLOOD PRESSURE. 2002;11(1):46-52

The potential economic consequences of cognitive improvement with losartan.

Jönsson L; Gerth W; Fastbom J
Article: JOURNAL OF ALZHEIMERS DISEASE. 2001;3(6):585-591

Blood pressure and dementia in persons 75+ years old: 3-year follow-up results from the Kungsholmen Project.

Guo Z; Qiu C; Viitanen M; Fastbom J; Winblad B; Fratiglioni L
Article: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2001;16(9):900-906

Psychotropic drug use in elderly people with and without dementia.

Giron MS; Forsell Y; Bernsten C; Thorslund M; Winblad B; Fastbom J
Article: NEUROLOGY. 2001;56(9):1188-1194

Vitamin B(12) and folate in relation to the development of Alzheimer's disease.

Wang HX; Wahlin A; Basun H; Fastbom J; Winblad B; Fratiglioni L
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2001;49(3):277-283

The appropriateness of drug use in an older nondemented and demented population.

Giron MS; Wang HX; Bernsten C; Thorslund M; Winblad B; Fastbom J
Article: JOURNAL OF NEUROSCIENCE RESEARCH. 2001;63(5):429-437

Calcium ionophore A23187 specifically decreases the secretion of beta-secretase cleaved amyloid precursor protein during apoptosis in primary rat cortical cultures.

Sennvik K; Benedikz E; Fastbom J; Sundström E; Winblad B; Ankarcrona M
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 2001;153(3):225-231

Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: variation by use of antihypertensive medication?

Guo Z; Fratiglioni L; Viitanen M; Lannfelt L; Basun H; Fastbom J; Winblad B
Article: CLINICAL DRUG INVESTIGATION. 2000;20(6):433-446

Quality of drug use in Swedish nursing homes - A follow-up study

Schmidt IK; Fastbom J
Article: JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES. 2000;55(5):P259-P265

The relationship between signs of cardiovascular deficiency and cognitive performance in old age: a population-based study.

Fahlander K; Wahlin A; Fastbom J; Grut M; Forsell Y; Hill RD; Winblad B; Bäckman L
Article: JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. 2000;55(6):M322-M328

Mild cognitive impairment in the population and physical health: data on 1,435 individuals aged 75 to 95.

Frisoni GB; Fratiglioni L; Fastbom J; Guo Z; Viitanen M; Winblad B
Article: NEUROSCIENCE LETTERS. 2000;278(3):169-172

Levels of alpha- and beta-secretase cleaved amyloid precursor protein in the cerebrospinal fluid of Alzheimer's disease patients.

Sennvik K; Fastbom J; Blomberg M; Wahlund LO; Winblad B; Benedikz E
Article: BRAIN RESEARCH. 1999;850(1-2):104-117

Quantitative autoradiography of [3H]forskolin binding sites in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits.

García-Jiménez A; Cowburn RF; Ohm TG; Bogdanovic N; Winblad B; Fastbom J
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 1999;150(10):1031-1044

Mortality in nondemented subjects with cognitive impairment: the influence of health-related factors.

Frisoni GB; Fratiglioni L; Fastbom J; Viitanen M; Winblad B
Article: NEUROREPORT. 1999;10(11):2423-2427

Inhibition of [3H]forskolin binding by Gpp[NH]p may reflect adenylate cyclase coupling to Gi.

Garcia-Jiménez A; Cowburn RF; Winblad B; Fastbom J
Article: ARCHIVES OF NEUROLOGY. 1999;56(8):991-996

Occurrence and progression of dementia in a community population aged 75 years and older: relationship of antihypertensive medication use.

Guo Z; Fratiglioni L; Zhu L; Fastbom J; Winblad B; Viitanen M
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 1999;29(1):29-43

Musculoskeletal pain and analgesic therapy in a very old population.

Grimby C; Fastbom J; Forsell Y; Thorslund M; Claesson CB; Winblad B
Article: BRAIN RESEARCH. 1999;818(2):383-396

A quantitative autoradiographic study of [3H]cAMP binding to cytosolic and particulate protein kinase A in post-mortem brain staged for Alzheimer's disease neurofibrillary changes and amyloid deposits.

Bonkale WL; Cowburn RF; Ohm TG; Bogdanovic N; Fastbom J
Article: NEUROSCIENCE. 1999;92(2):499-513

Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and beta-amyloid pathologies.

Kelliher M; Fastbom J; Cowburn RF; Bonkale W; Ohm TG; Ravid R; Sorrentino V; O'Neill C
Article: CLINICAL DRUG INVESTIGATION. 1999;17(5):389-398

Drug use patterns in a very elderly population - A seven-year review

Giron MST; Claesson C; Thorslund M; Oke T; Winblad B; Fastbom J
Article: AMERICAN JOURNAL OF EPIDEMIOLOGY. 1998;148(9):887-892

Cognitive impairment, drug use, and the risk of hip fracture in persons over 75 years old: a community-based prospective study.

Guo Z; Wills P; Viitanen M; Fastbom J; Winblad B
Article: NEUROREPORT. 1998;9(14):3329-3333

Inhibition of [3H]forskolin binding by Gpp[NH]p may reflect adenylyl cyclase coupling to Gi.

García-Jiménez A; Cowburn RF; Einblad B; Fastbom J
Article: BRAIN RESEARCH. 1998;796(1-2):209-221

Loss of inositol 1,4,5-trisphosphate receptor sites and decreased PKC levels correlate with staging of Alzheimer's disease neurofibrillary pathology.

Kurumatani T; Fastbom J; Bonkale WL; Bogdanovic N; Winblad B; Ohm TG; Cowburn RF
Article: ALZHEIMER DISEASE & ASSOCIATED DISORDERS. 1998;12(1):14-17

Benzodiazepines may have protective effects against Alzheimer disease.

Fastbom J; Forsell Y; Winblad B
Article: CLINICAL DRUG INVESTIGATION. 1998;15(6):497-506

Drug use and low blood pressure in the elderly: a study of data from the kungsholmen project.

Passare G; Guo Z; Winblad B; Fastbom J
Article: AGE AND AGEING. 1997;26(5):383-391

Drug use by demented and non-demented elderly people.

Wills P; Claesson CB; Fratiglioni L; Fastbom J; Thorslund M; Winblad B
Article: NEUROCHEMICAL RESEARCH. 1997;22(8):1055-1063

Autoradiographic characterisation of [35S]GTP gamma S binding sites in rat brain.

García-Jiménez A; Cowburn RF; Winblad B; Fastbom J
Article: BRAIN RESEARCH. 1997;763(1):1-13

Autoradiographic characterization of [3H]cGMP binding sites in the rat brain.

Bonkale WL; Cowburn RF; Winblad B; Fastbom J
Article: JOURNAL OF NEURAL TRANSMISSION. 1997;104(2-3):175-189

Autoradiographic characterization of [3H]inositol (1,4,5) trisphosphate and [3H]inositol (1,3,4,5) tetrakisphosphate binding sites in human brain.

Kurumatani T; Cowburn RF; Bogdanovic N; Winblad B; Fastbom J
Article: CLINICAL DRUG INVESTIGATION. 1997;13(2):105-117

: prevalence and association with drug use.

Cornelius C; Fastbom J; Claesson CB; Wills P; Thorslund M; Viitanen M; Winblad B
Article: BRAIN RESEARCH. 1996;737(1-2):155-161

Impaired G-protein-stimulated adenylyl cyclase activity in Alzheimer's disease brain is not accompanied by reduced cyclic-AMP-dependent protein kinase A activity.

Bonkale WL; Fastbom J; Wiehager B; Ravid R; Winblad B; Cowburn RF
Article: ARCHIVES OF GERONTOLOGY AND GERIATRICS. 1996;23(2):179-188

Levels of serum creatinine and estimated creatinine clearance over the age of 75: a study of an elderly Swedish population.

Fastbom J; Wills P; Cornelius C; Viitanen M; Winblad B
Article: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 1996;44(1):54-60

Use of cardiovascular drugs in an older Swedish population.

Wills P; Fastbom J; Claesson CB; Cornelius C; Thorslund M; Winblad B
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Review: BMC GERIATRICS. 2023;23(1):155

Few geriatric heart failure patients investigated according to clinical guidelines: a retrospective review of patient records.

Wessberg MR; Seiger Å; Fastbom J; Eriksdotter M
Letter: JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. 2016;17(10):957-958

Expanding the Proportion of Life With Polypharmacy in Sweden: 2006-2013.

Wastesson JW; Fastbom J; Johnell K
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2016;64(9):1927-1928

Response to Timo E. Strandberg.

Gnjidic D; Fastbom J; Johnell K
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2016;64(1):223-224

Statin Therapy and Dementia in Older Adults: Role of Disease Severity and Multimorbidity.

Gnjidic D; Fastbom J; Fratiglioni L; Rizzuto D; Angleman S; Johnell K
Review: DRUGS & AGING. 2015;32(3):189-199

National indicators for quality of drug therapy in older persons: the Swedish experience from the first 10 years.

Fastbom J; Johnell K
Review: LAKARTIDNINGEN. 2006;103(6):369-371

[Administration of symptom-relieving drugs in Alzheimer disease is beneficial].

Nordberg A; Eriksdotter-Jönhagen M; Garlind A; Grut M; Freund-Levi Y; Cornelius C; Ekström A; Fastbom J; Sedvall M; Viitanen M
Review: INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY. 2005;20(3):201-217

Clinical trials of potential antidepressants: to what extent are the elderly represented: a review.

Giron MST; Fastbom J; Winblad B
Meeting abstract: NEUROBIOLOGY OF AGING. 2004;25:S53

Heart failure and risk of dementia in the kungsholmen project: A six-year follow-up study

Qiu CX; Winblad B; Marengoni A; Fastbom J; Fratiglioni L
Letter: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 2002;50(3):590-591

Are the unsafe combinations always inappropriate? In Reply

Giron MST; Wang HX; Winbald B; Fastbom J; Bernstein C; Thorslund M
Review: LAKARTIDNINGEN. 2001;98(14):1674-1679

[Increased consumption of drugs among the elderly results in greater risk of problems].

Fastbom J
Published conference paper: BIOCHEMICAL SOCIETY SYMPOSIUM. 2001;(67):177-194

Dysfunctional intracellular calcium homoeostasis: a central cause of neurodegeneration in Alzheimer's disease.

O'Neill C; Cowburn RF; Bonkale WL; Ohm TG; Fastbom J; Carmody M; Kelliher M
Published conference paper: BIOCHEMICAL SOCIETY SYMPOSIUM. 2001;(67):163-175

Receptor-G-protein signalling in Alzheimer's disease.

Cowburn RF; O'Neill C; Bonkale WL; Ohm TG; Fastbom J
Other: JOURNAL OF THE AMERICAN GERIATRICS SOCIETY. 1995;43(10):1135-1140

The use of medicines with anticholinergic effects in older people: a population study in an urban area of Sweden.

Fastbom J; Claesson CB; Cornelius C; Thorslund M; Winblad B

Anställningar

Professor, Neurobiologi, vårdvetenskap och samhälle, Karolinska Institutet, 2011-

Examina och utbildning

Docent, Geriatrisk farmakologi, Karolinska Institutet, 1998

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