Joar Guterstam

Om mig
Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Om mig

Leg läkare, specialist i psykiatri och beroendemedicin
Medicine doktor

Forskningsbeskrivning

Min doktorsavhandling (2017) handlade om hur hjärnans opioidsystem är involverat i amfetaminberoende, vilket undersöktes med hjärnavbildningsteknikerna PET och fMRI. Som post-doc har jag sysslat med klinisk beroendeforskning, både på Karolinska Institutet och som gästforskare vid Zentralinstitut für Seelische Gesundheit i Mannheim, Tyskland. Jag arbetar fortfarande med hjärnavbildning, men också med kliniska prövningar av läkemedel för beroendetillstånd.

Artiklar

Article: PSYCHOLOGICAL MEDICINE. 2024;54(7):1391-1402

The risk and development of work disability among individuals with gambling disorder: a longitudinal case-cohort study in Sweden.

Månsson V; Pettersson E; Mittendorfer-Rutz E; Guterstam J; Berman AH; Jayaram-Lindström N; Molero Y
Article: EUROPEAN ADDICTION RESEARCH. 2024;30(1):1-13

The Effect of Methylphenidate on Cognition in Patients with Comorbid Attention Deficit/Hyperactivity Disorder and Amphetamine Use Disorder: An Exploratory Single-Blinded within-Subject Study.

Brynte C; Konstenius M; Khemiri L; Bäcker A; Guterstam J; Levin FR; Jayaram-Lindström N; Franck J
Article: BMC PUBLIC HEALTH. 2023;23(1):1608

A study protocol for a European, mixed methods, prospective, cohort study of the effectiveness of naloxone administration by community members, in reversing opioid overdose: NalPORS.

Metrebian N; Carter B; Eide D; McDonald R; Neale J; Parkin S; Dascal T; Mackie C; Day E; Guterstam J; Horsburgh K; Kåberg M; Kelleher M; Smith J; Thiesen H; Strang J
Article: LAKARTIDNINGEN. 2022;119

Spelberoende – en allvarlig biverkan av dopaminagonister.

Guterstam J
Article: EUROPEAN ADDICTION RESEARCH. 2022;28(3):210-219

The Hypothesis of Subliminal Cue Reactivity in Addiction Revisited: An fMRI Study.

Guterstam J; Jayaram-Lindström N; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
Article: BMC PSYCHIATRY. 2021;21(1):458

Self-rated impulsivity in healthy individuals, substance use disorder and ADHD: psychometric properties of the Swedish Barratt impulsiveness scale.

Khemiri L; Brynte C; Konstenius M; Guterstam J; Rosendahl I; Franck J; Jayaram-Lindström N
Article: LAKARTIDNINGEN. 2020;117:20165

Välkommet med ny standard för kiral analys av amfetamin.

Guterstam J
Article: PSYCHOPHARMACOLOGY. 2020;237(1):69-82

Effects of the monoamine stabilizer (-)OSU6162 on cognitive function in alcohol dependence.

Khemiri L; Steensland P; Guterstam J; de Manzano Ö; Franck J; Jayaram-Lindström N
Article: MOLECULAR PAIN. 2020;16:1744806920927625-174480692092762

Naltrexone during pain conditioning: A double-blind placebo-controlled experimental trial.

Pontén M; Fust J; Kosek E; Guterstam J; Jensen K
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s177

Subliminal cue reactivity in amphetamine dependence

Guterstam J; Jayaram-Lindstrom N; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
Article: DRUG AND ALCOHOL DEPENDENCE. 2018;191:91-97

Cue reactivity and opioid blockade in amphetamine dependence: A randomized, controlled fMRI study.

Guterstam J; Jayaram-Lindström N; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:s1064-s1065

P.6.d.003 Cue reactivity and opioid blockade in amphetamine dependence: a randomised, controlled fMRI study

Guterstam J; Lindström NJ; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
Article: TRANSLATIONAL PSYCHIATRY. 2017;7(4):e1104

Naltrexone modulates dopamine release following chronic, but not acute amphetamine administration: a translational study.

Jayaram-Lindström N; Guterstam J; Häggkvist J; Ericson M; Malmlöf T; Schilström B; Halldin C; Cervenka S; Saijo T; Nordström A-L; Franck J
Article: LAKARTIDNINGEN. 2016;113:DSU6

[Substitution therapy tested against amphetamine dependence].

Bloniecki Kallio V; Guterstam J; Franck J
Article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2015;25(12):2240-2251

The effects of the monoamine stabilizer (-)-OSU6162 on craving in alcohol dependent individuals: A human laboratory study.

Khemiri L; Steensland P; Guterstam J; Beck O; Carlsson A; Franck J; Jayaram-Lindström N
Article: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2015;39(11):2189-2199

Varenicline for treatment of alcohol dependence: a randomized, placebo-controlled trial.

de Bejczy A; Löf E; Walther L; Guterstam J; Hammarberg A; Asanovska G; Franck J; Isaksson A; Söderpalm B
Article: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2015;39(11):2200-2208

Phosphatidylethanol is superior to carbohydrate-deficient transferrin and γ-glutamyltransferase as an alcohol marker and is a reliable estimate of alcohol consumption level.

Walther L; de Bejczy A; Löf E; Hansson T; Andersson A; Guterstam J; Hammarberg A; Asanovska G; Franck J; Söderpalm B; Isaksson A
Article: ADDICTION. 2014;109(3):440-449

Methylphenidate for attention deficit hyperactivity disorder and drug relapse in criminal offenders with substance dependence: a 24-week randomized placebo-controlled trial.

Konstenius M; Jayaram-Lindström N; Guterstam J; Beck O; Philips B; Franck J
Article: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2013;16(4):763-769

Effects of amphetamine on the human brain opioid system--a positron emission tomography study.

Guterstam J; Jayaram-Lindström N; Cervenka S; Frost JJ; Farde L; Halldin C; Franck J
Journal article: LAKARTIDNINGEN. 2013;110(3):101

[Time for intellectual honesty in the substance abuse debate].

Guterstam J
Journal article: EUROPEAN PSYCHIATRY. 2013;28:1

1128 – Methylphenidate for ADHD in adults with substance dependence: A 24-week randomized placebo-controlled trial

Konstenius M; Jayaram-Lindström N; Guterstam J; Philips B; Beck O; Franck J
Article: BMC PSYCHIATRY. 2012;12:221

Amphetamine-induced psychosis--a separate diagnostic entity or primary psychosis triggered in the vulnerable?

Bramness JG; Gundersen ØH; Guterstam J; Rognli EB; Konstenius M; Løberg E-M; Medhus S; Tanum L; Franck J
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2012;22:s55

P.3.004 Amphetamine-opioid interactions in the human brain reward system – a PET study using [11C]carfentanil

Guterstam J; Jayaram-Lindstrom N; Cervenka S; Halldin C; Farde L; Frost J; Franck J
Article: PLOS ONE. 2012;7(6):e39882

Alcohol dependence associated with increased utilitarian moral judgment: a case control study.

Khemiri L; Guterstam J; Franck J; Jayaram-Lindström N
Journal article: LAKARTIDNINGEN. 2006;103(15-16):1225

[Exaggerated simplification of animal ethics].

Guterstam J; Sjöstrand M
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Alla övriga publikationer

Review: LAKARTIDNINGEN. 2022;119:21105

[The dark side of ADHD - comorbidity with substance use disorder and criminality - an overview].

Johansson Capusan A; Guterstam J; Ginsberg Y; Borg Skoglund L
KI thesis / dissertation: 2017

Imaging of the brain opioid system in amphetamine dependence

Guterstam, Joar
Meeting abstract: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S1054

Effect of the monoamine stabilizer (-)-OSU6162 on cognitive function in alcohol dependent patients

Khemiri L; Steensland P; Guterstam J; Carlsson A; Franck J; Jayaram-Lindstrom N
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2017;27:S1065-S1066

Cue reactivity and opioid blockade in amphetamine dependence: a randomised, controlled fMRI study

Guterstam J; Lindstrom NJ; Berrebi J; Petrovic P; Ingvar M; Fransson P; Franck J
Letter: LAKARTIDNINGEN. 2015;112:DEEX

["Dialogical floor" can become a trap door].

Guterstam J; Hammarberg A; Finn SW; Cervenka S; Lekander M; Petrovic P; Hedman E
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2014;24:S691-S692

Neural correlates of cue-induced craving for amphetamine

Guterstam J; Jayaram-Lindstrom N; Berrebi J; Ingvar M; Franck J
Corrigendum: ADDICTION. 2014;109(9):1571-1572

Methylphenidate for attention deficit hyperactivity disorder and drug relapse in criminal offenders with substance dependence: a 24-week randomized placebo-controlled trial (vol 109, pg 440, 2014)

Konstenius M; Jayaram-Lindstroem N; Guterstam J; Beck O; Philips B; Franck J
Conference publication: EUROPEAN PSYCHIATRY. 2014;28:e109

METHYLPHENIDATE FOR ADHD IN ADULTS WITH SUBSTANCE DEPENDENCE A 24-WEEK RANDOMIZED PLACEBO-CONTROLLED TRIAL

Konstenius M; Jayaram-Lindstrom N; Guterstam J; Philips B; Beck O; Franck J
Conference publication: BIOLOGICAL PSYCHIATRY. 2014;75(9):18S

The Effects of the Monoamine Stabilizer (-)-OSU6162 on Craving in Alcohol Dependent Patients

Khemiri L; Steensland P; Guterstam J; Carlsson A; Jayaram-Lindstrom N; Franck J
Conference publication: BIOLOGICAL PSYCHIATRY. 2014;75(9):379S

Effects of Naltrexone on Amphetamine-induced Changes in the Brain Dopamine System: Pre-clinical and Clinical Studies

Jayaram-Lindstrom N; Haggkvist J; Guterstam J; Malmlof T; Halldin C; Schilstrom B; Nordstrom A-L; Franck J
Conference publication: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2014;38:306A

EVALUATION OF THEMONOAMINE STABILIZER (-)-OSU6162 AS A POTENTIAL NOVEL TREATMENT OF ALCOHOL USE DISORDERS - FROM BENCH TOCLINIC

Jayaram-Lindstrom N; Khemiri L; Carlsson A; Guterstam J; Steensland P; Franck J
Conference publication: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2014;38:158A

THE MONOAMINE STABILIZER (-)-OSU6162 MODULATES CRAVING IN ALCOHOL DEPENDENT SUBJECTS

Khemiri L; Steensland P; Guterstam J; Carlsson A; Jayaram-Lindstrom N; Franck J
Conference publication: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2012;36:64A

THE ETHANOL-nAChR INTERACTION AND ITS RELEVANCE FOR MODULATING ETHANOL CONSUMPTION IN RODENTS AND MAN

Soderpalm B; deBejczy A; Ericson M; Guterstam J; Hammarberg A; Franck J; Asanovska G; Lof E
Conference publication: ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. 2012;36:358A

A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY OF THE EFFECT OF VARENICLINE IN THE TREATMENT OF ALCOHOL DEPENDENCE

Lof E; deBejczy A; Guterstam J; Hammarberg A; Franck J; Asanovska G; Soderpalm B
Conference publication: INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2012;15:41

ADHD in drug addiction : A RCT on the feasibility of methylphenidate treatment in criminal amphetamine users

Franck J; Konstenius M; Jayaram-Lindstrom N; Philips B; Guterstam J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2012;22:S55

Amphetamine-opioid interactions in the human brain reward system - a PET study using [¹¹C]carfentanil

Guterstam J; Jayaram-Lindstrom N; Cervenka S; Halldin C; Farde L; Frost J; Franck J

Forskningsbidrag

Prescription opioid misuse: improving prevention and treatment

Swedish Research Council for Health Working Life and Welfare

1 January 2021 - 31 December 2023
ADHD and co-occuring substance use disorder: a clinical trials programme of pharmacological treatments

Swedish Research Council

1 January 2013 - 31 December 2015
Development of a new psychopharmacological treatment for amphetamine dependence and ADHD: Clinical and experimental studies

Swedish Research Council

1 January 2010 - 31 December 2012

Anställningar

Anknuten till Forskning, Klinisk neurovetenskap, Karolinska Institutet, 2024-2026

Examina och utbildning

Medicine Doktorsexamen, Karolinska Institutet, 2017
Läkarexamen, Karolinska Institutet, 2006

Om mig

Forskningsbeskrivning

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Nyheter från KI

Kalenderhändelser från KI