Jette Lengefeld

Publikationer
Forskningsbidrag
Populärvetenskap och samverkan

Artiklar

Journal article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2023;11:1219294

Editorial: Cell size regulation: molecular mechanisms and physiological importance.

Lengefeld J; Zatulovskiy E
Journal article: BMC BIOLOGY. 2022;20(1):174

Segmentation, tracking and cell cycle analysis of live-cell imaging data with Cell-ACDC.

Padovani F; Mairhörmann B; Falter-Braun P; Lengefeld J; Schmoller KM
Journal article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2022;10:1036602

Cellular enlargement - A new hallmark of aging?

Davies DM; van den Handel K; Bharadwaj S; Lengefeld J
Journal article: SCIENCE ADVANCES. 2021;7(46):eabk0271

Cell size is a determinant of stem cell potential during aging.

Lengefeld J; Cheng C-W; Maretich P; Blair M; Hagen H; McReynolds MR; Sullivan E; Majors K; Roberts C; Kang JH; Steiner JD; Miettinen TP; Manalis SR; Antebi A; Morrison SJ; Lees JA; Boyer LA; Yilmaz ÖH; Amon A
Journal article: EXPERIMENTAL HEMATOLOGY. 2021;100:s54

3022 – CELL SIZE IS A DETERMINANT OF STEM CELL POTENTIAL DURING AGING

Lengefeld J; Amon A
Journal article: CELL. 2019;176(5):1083-1097.e18

Excessive Cell Growth Causes Cytoplasm Dilution And Contributes to Senescence.

Neurohr GE; Terry RL; Lengefeld J; Bonney M; Brittingham GP; Moretto F; Miettinen TP; Vaites LP; Soares LM; Paulo JA; Harper JW; Buratowski S; Manalis S; van Werven FJ; Holt LJ; Amon A
Journal article: BIOESSAYS. 2018;40(8):e1800038

Asymmetric Segregation of Aged Spindle Pole Bodies During Cell Division: Mechanisms and Relevance Beyond Budding Yeast?

Lengefeld J; Barral Y
Journal article: MOLECULAR BIOLOGY OF THE CELL. 2018;29(1):10-28

Spatial cues and not spindle pole maturation drive the asymmetry of astral microtubules between new and preexisting spindle poles.

Lengefeld J; Yen E; Chen X; Leary A; Vogel J; Barral Y
Journal article: NATURE CELL BIOLOGY. 2017;19(8):941-951

Budding yeast Wee1 distinguishes spindle pole bodies to guide their pattern of age-dependent segregation.

Lengefeld J; Hotz M; Rollins M; Baetz K; Barral Y
Journal article: PLOS GENETICS. 2015;11(2):e1004938

Asymmetry of the budding yeast Tem1 GTPase at spindle poles is required for spindle positioning but not for mitotic exit.

Scarfone I; Venturetti M; Hotz M; Lengefeld J; Barral Y; Piatti S
Journal article: JOURNAL OF BIOTECHNOLOGY. 2014;191:214-220

The nucleotide composition of the spacer sequence influences the expression yield of heterologously expressed genes in Bacillus subtilis.

Liebeton K; Lengefeld J; Eck J
Journal article: PLOS BIOLOGY. 2014;12(2):e1001793

Cecum lymph node dendritic cells harbor slow-growing bacteria phenotypically tolerant to antibiotic treatment.

Kaiser P; Regoes RR; Dolowschiak T; Wotzka SY; Lengefeld J; Slack E; Grant AJ; Ackermann M; Hardt W-D
Journal article: CELL CYCLE. 2012;11(16):3109-3116

The MEN mediates the effects of the spindle assembly checkpoint on Kar9-dependent spindle pole body inheritance in budding yeast.

Hotz M; Lengefeld J; Barral Y
Journal article: PLOS ONE. 2012;7(4):e34812

Salmonella transiently reside in luminal neutrophils in the inflamed gut.

Loetscher Y; Wieser A; Lengefeld J; Kaiser P; Schubert S; Heikenwalder M; Hardt W-D; Stecher B

Alla övriga publikationer

Preprint: BIORXIV. 2021

Cell-ACDC: a user-friendly toolset embedding state-of-the-art neural networks for segmentation, tracking and cell cycle annotations of live-cell imaging data

Padovani F; Mairhörmann B; Falter-Braun P; Lengefeld J; Schmoller KM
Preprint: BIORXIV. 2020

Cell size is a determinant of stem cell potential during aging

Lengefeld J; Cheng C-W; Maretich P; Blair M; Hagen H; McReynolds MR; Sullivan E; Majors K; Roberts C; Kang JH; Steiner JD; Miettinen TP; Manalis SR; Antebi A; Morrison SJ; Lees JA; Boyer LA; Yilmaz ÖH; Amon A

Forskningsbidrag

Cell size as driver of stem cell aging and cancer

European Research Council (ERC) - Starting Grant

1 January 2024 - 31 December 2028
Size as a driver of stem cell ageing and cancer

Swedish Research Council

1 January 2023 - 31 December 2026
Centre of Excellence in Stem Cell Metabolism

Academy of Finland

13 December 2022 - 31 December 2025
Jeanssons Stiftelser

1 January 2022 - 31 December 2023
Investigating Cellular and Molecular Signals in Leukemia Initiation

Cancer Foundation Finland

23 November 2021
Impact of cell size in regulating stem cell function during aging and disease

Academy of Finland

3 May 2021 - 31 August 2026
Investigating niche- and hematopoietic-derived signals in leukemia initiation. Verisolujen sekä mikroympäristön välittämien signaalien kartoittaminen leukemian synnyssä.

Cancer Foundation Finland

10 November 2020
Identification of mTORC1-dependent mechanisms driving senescence

Swiss National Science Foundation

1 January 2017 - 30 June 2018
Mechanism of centrosome specification

Swiss National Science Foundation

1 December 2013 - 30 November 2016
Mechanism and Function of Spindle Asymmetry

Swiss National Science Foundation

1 January 2010 - 30 June 2013

Artiklar

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Forskningsbidrag

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