Isabell Brikell

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: BIOLOGICAL PSYCHIATRY. 2024;95(5):444-452

Attention-Deficit/Hyperactivity Disorder and Major Depressive Disorder: Evidence From Multiple Genetically Informed Designs.

Garcia-Argibay M; Brikell I; Thapar A; Lichtenstein P; Lundström S; Demontis D; Larsson H
Journal article: NATURE GENETICS. 2024;56(2):234-244

Polygenic profiles define aspects of clinical heterogeneity in attention deficit hyperactivity disorder.

LaBianca S; Brikell I; Helenius D; Loughnan R; Mefford J; Palmer CE; Walker R; Gådin JR; Krebs M; Appadurai V; Vaez M; Agerbo E; Pedersen MG; Børglum AD; Hougaard DM; Mors O; Nordentoft M; Mortensen PB; Kendler KS; Jernigan TL; Geschwind DH; Ingason A; Dahl AW; Zaitlen N; Dalsgaard S; Werge TM; Schork AJ
Article: JAMA PSYCHIATRY. 2024;81(2):178-187

Attention-Deficit/Hyperactivity Disorder Medications and Long-Term Risk of Cardiovascular Diseases.

Zhang L; Li L; Andell P; Garcia-Argibay M; Quinn PD; D'Onofrio BM; Brikell I; Kuja-Halkola R; Lichtenstein P; Johnell K; Larsson H; Chang Z
Article: LANCET PSYCHIATRY. 2024;11(1):16-26

ADHD medication discontinuation and persistence across the lifespan: a retrospective observational study using population-based databases.

Brikell I; Yao H; Li L; Astrup A; Gao L; Gillies MB; Xie T; Zhang-James Y; Dalsgaard S; Engeland A; Faraone SV; Haavik J; Hartman C; Ip P; Jakobsdóttir Smári U; Larsson H; Man KK; de Oliveira Costa J; Pearson S-A; Hostrup Nielsen NP; Snieder H; Wimberley T; Wong IC; Zhang L; Zoega H; Klungsøyr K; Chang Z
Article: JAMA PSYCHIATRY. 2024;81(1):25-33

Antidepressant Use and Risk of Manic Episodes in Children and Adolescents With Unipolar Depression.

Virtanen S; Lagerberg T; Takami Lageborn C; Kuja-Halkola R; Brikell I; Matthews AA; Lichtenstein P; D'Onofrio BM; Landén M; Chang Z
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2023;75:s30-s31

ENHANCING POLYGENIC PREDICTION WITH AN AGNOSTIC MULTI-PGS METHOD THAT LEVERAGES HUNDREDS OF POLYGENIC SCORES

Albinana C; Zhu Z; Schork A; Ingason A; Aschard H; Brikell I; Petersen L; Agerbo E; Grove J; Borglum A; Mortensen PB; McGrath J; Neale B; Prive F; Vilhjalmsson B
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2023;75:s203

GENOME-WIDE ASSOCIATION STUDY OF BORDER-LINE PERSONALITY DISORDER ACCOUNTING FOR AGE AT DIAGNOSIS AND FAMILY HISTORY IN IPSYCH

Hall ASM; Steinbach J; Pedersen EM; Mundy JR; Agerbo E; Ostergaard SD; Debost J-CP; Vilhjalmsson BJ; Brikell I; Musliner KL
Article: JCPP ADVANCES. 2023;3(3):e12158

Attention-deficit/hyperactivity disorder is associated with increased risk of cardiovascular diseases: A systematic review and meta-analysis.

Li L; Yao H; Zhang L; Garcia-Argibay M; Du Rietz E; Brikell I; Solmi M; Cortese S; Ramos-Quiroga JA; Ribasés M; Chang Z; Larsson H
Journal article: NATURE COMMUNICATIONS. 2023;14(1):4702

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores.

Albiñana C; Zhu Z; Schork AJ; Ingason A; Aschard H; Brikell I; Bulik CM; Petersen LV; Agerbo E; Grove J; Nordentoft M; Hougaard DM; Werge T; Børglum AD; Mortensen PB; McGrath JJ; Neale BM; Privé F; Vilhjálmsson BJ
Article: MOVEMENT DISORDERS. 2023;38(8):1419-1427

Early-Life and Family Risk Factors for Tic Disorder Persistence into Adulthood.

Mataix-Cols D; Isomura K; Brander G; Brikell I; Lichtenstein P; Chang Z; Larsson H; Kuja-Halkola R; Black KJ; Sidorchuk A; Fernández de la Cruz L
Article: LANCET PUBLIC HEALTH. 2023;8(6):e432-e441

Post-traumatic stress disorder and the risk of violent crime conviction in Sweden: a nationwide, register-based cohort study.

Paulino A; Kuja-Halkola R; Fazel S; Sariaslan A; Rietz ED; Lichtenstein P; Brikell I
Journal article: NATURE GENETICS. 2023;55(2):198-208

Genome-wide analyses of ADHD identify 27 risk loci, refine the genetic architecture and implicate several cognitive domains.

Demontis D; Walters GB; Athanasiadis G; Walters R; Therrien K; Nielsen TT; Farajzadeh L; Voloudakis G; Bendl J; Zeng B; Zhang W; Grove J; Als TD; Duan J; Satterstrom FK; Bybjerg-Grauholm J; Bækved-Hansen M; Gudmundsson OO; Magnusson SH; Baldursson G; Davidsdottir K; Haraldsdottir GS; Agerbo E; Hoffman GE; Dalsgaard S; Martin J; Ribasés M; Boomsma DI; Soler Artigas M; Roth Mota N; Howrigan D; Medland SE; Zayats T; Rajagopal VM; ADHD Working Group of the Psychiatric Genomics Con; iPSYCH-Broad Consortium; Nordentoft M; Mors O; Hougaard DM; Mortensen PB; Daly MJ; Faraone SV; Stefansson H; Roussos P; Franke B; Werge T; Neale BM; Stefansson K; Børglum AD
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2023;180(1):73-88

Interplay of ADHD Polygenic Liability With Birth-Related, Somatic, and Psychosocial Factors in ADHD: A Nationwide Study.

Brikell I; Wimberley T; Albiñana C; Vilhjálmsson BJ; Agerbo E; Børglum AD; Demontis D; Schork AJ; LaBianca S; Werge T; Hougaard DM; Nordentoft M; Mors O; Mortensen PB; Petersen LV; Dalsgaard S
Article: EVIDENCE-BASED MENTAL HEALTH. 2022;25(4):185-190

Risk prediction model for cardiovascular diseases in adults initiating pharmacological treatment for attention-deficit/hyperactivity disorder.

Dobrosavljevic M; Fazel S; Du Rietz E; Li L; Zhang L; Chang Z; Jernberg T; Faraone SV; Jendle J; Chen Q; Brikell I; Larsson H
Article: WORLD PSYCHIATRY. 2022;21(3):452-459

Attention-deficit/hyperactivity disorder as a risk factor for cardiovascular diseases: a nationwide population-based cohort study.

Li L; Chang Z; Sun J; Garcia-Argibay M; Du Rietz E; Dobrosavljevic M; Brikell I; Jernberg T; Solmi M; Cortese S; Larsson H
Article: BMC PSYCHIATRY. 2022;22(1):573

Temporally ordered associations between type 2 diabetes and brain disorders - a Danish register-based cohort study.

Wimberley T; Horsdal HT; Brikell I; Laursen TM; Astrup A; Fanelli G; Bralten J; Poelmans G; Gils VV; Jansen WJ; Vos SJB; Bertaina-Anglade V; Camacho-Barcia L; Mora-Maltas B; Fernandez-Aranda F; Bonet MB; Salas-Salvadó J; Franke B; Dalsgaard S
Article: ACTA PSYCHIATRICA SCANDINAVICA. 2022;145(6):604-614

Temporal changes in sex- and age-specific incidence profiles of mental disorders-A nationwide study from 1970 to 2016.

Plana-Ripoll O; Momen NC; McGrath JJ; Wimberley T; Brikell I; Schendel D; Thygesen M; Weye N; Pedersen CB; Mors O; Mortensen PB; Dalsgaard S
Article: TRANSLATIONAL PSYCHIATRY. 2022;12(1):152

The role of ADHD genetic risk in mid-to-late life somatic health conditions.

Garcia-Argibay M; du Rietz E; Lu Y; Martin J; Haan E; Lehto K; Bergen SE; Lichtenstein P; Larsson H; Brikell I
Article: JOURNAL OF CLINICAL PSYCHIATRY. 2022;83(1):21m14033

Early-Life Injuries and the Development of Attention-Deficit/Hyperactivity Disorder.

Wimberley T; Brikell I; Pedersen EM; Agerbo E; Vilhjálmsson BJ; Albiñana C; Privé F; Thapar A; Langley K; Riglin L; Simonsen M; Nielsen HS; Børglum AD; Nordentoft M; Mortensen PB; Dalsgaard S
Article: SCIENTIFIC REPORTS. 2021;11(1):23402

Harnessing Twitter data to survey public attention and attitudes towards COVID-19 vaccines in the UK.

Fazel S; Zhang L; Javid B; Brikell I; Chang Z
Article: JCPP ADVANCES. 2021;1(3):e12030

The association between polygenic scores for attention-deficit/hyperactivity disorder and school performance: The role of attention-deficit/hyperactivity disorder symptoms, polygenic scores for educational attainment, and shared familial factors.

Jangmo A; Brikell I; Kuja-Halkola R; Feldman I; Lundström S; Almqvist C; Bulik CM; Larsson H
Article: BEHAVIOR GENETICS. 2021;51(5):592-606

Continuity of Genetic Risk for Aggressive Behavior Across the Life-Course.

van der Laan CM; Morosoli-García JJ; van de Weijer SGA; Colodro-Conde L; ACTION Consortium; Lupton MK; Mitchell BL; McAloney K; Parker R; Burns JM; Hickie IB; Pool R; Hottenga J-J; Martin NG; Medland SE; Nivard MG; Boomsma DI
Article: LANCET PSYCHIATRY. 2021;8(9):774-783

Mapping phenotypic and aetiological associations between ADHD and physical conditions in adulthood in Sweden: a genetically informed register study.

Du Rietz E; Brikell I; Butwicka A; Leone M; Chang Z; Cortese S; D'Onofrio BM; Hartman CA; Lichtenstein P; Faraone SV; Kuja-Halkola R; Larsson H
Article: AMERICAN JOURNAL OF PSYCHIATRY. 2021;178(9):854-864

Genetic, Clinical, and Sociodemographic Factors Associated With Stimulant Treatment Outcomes in ADHD.

Brikell I; Wimberley T; Albiñana C; Pedersen EM; Vilhjálmsson BJ; Agerbo E; Demontis D; Børglum AD; Schork AJ; LaBianca S; Werge T; Mors O; Hougaard DM; Thapar A; Mortensen PB; Dalsgaard S
Article: TRANSLATIONAL PSYCHIATRY. 2021;11(1):413

Genetic association study of childhood aggression across raters, instruments, and age.

Ip HF; van der Laan CM; Krapohl EML; Brikell I; Sánchez-Mora C; Nolte IM; St Pourcain B; Bolhuis K; Palviainen T; Zafarmand H; Colodro-Conde L; Gordon S; Zayats T; Aliev F; Jiang C; Wang CA; Saunders G; Karhunen V; Hammerschlag AR; Adkins DE; Border R; Peterson RE; Prinz JA; Thiering E; Seppälä I; Vilor-Tejedor N; Ahluwalia TS; Day FR; Hottenga J-J; Allegrini AG; Rimfeld K; Chen Q; Lu Y; Martin J; Soler Artigas M; Rovira P; Bosch R; Español G; Ramos Quiroga JA; Neumann A; Ensink J; Grasby K; Morosoli JJ; Tong X; Marrington S; Middeldorp C; Scott JG; Vinkhuyzen A; Shabalin AA; Corley R; Evans LM; Sugden K; Alemany S; Sass L; Vinding R; Ruth K; Tyrrell J; Davies GE; Ehli EA; Hagenbeek FA; De Zeeuw E; Van Beijsterveldt TCEM; Larsson H; Snieder H; Verhulst FC; Amin N; Whipp AM; Korhonen T; Vuoksimaa E; Rose RJ; Uitterlinden AG; Heath AC; Madden P; Haavik J; Harris JR; Helgeland Ø; Johansson S; Knudsen GPS; Njolstad PR; Lu Q; Rodriguez A; Henders AK; Mamun A; Najman JM; Brown S; Hopfer C; Krauter K; Reynolds C; Smolen A; Stallings M; Wadsworth S; Wall TL; Silberg JL; Miller A; Keltikangas-Järvinen L; Hakulinen C; Pulkki-Råback L; Havdahl A; Magnus P; Raitakari OT; Perry JRB; Llop S; Lopez-Espinosa M-J; Bønnelykke K; Bisgaard H; Sunyer J; Lehtimäki T; Arseneault L; Standl M; Heinrich J; Boden J; Pearson J; Horwood LJ; Kennedy M; Poulton R; Eaves LJ; Maes HH; Hewitt J; Copeland WE; Costello EJ; Williams GM; Wray N; Järvelin M-R; McGue M; Iacono W; Caspi A; Moffitt TE; Whitehouse A; Pennell CE; Klump KL; Burt SA; Dick DM; Reichborn-Kjennerud T; Martin NG; Medland SE; Vrijkotte T; Kaprio J; Tiemeier H; Davey Smith G; Hartman CA; Oldehinkel AJ; Casas M; Ribasés M; Lichtenstein P; Lundström S; Plomin R; Bartels M; Nivard MG; Boomsma DI
Article: NATURE COMMUNICATIONS. 2021;12(1):576

Risk variants and polygenic architecture of disruptive behavior disorders in the context of attention-deficit/hyperactivity disorder.

Demontis D; Walters RK; Rajagopal VM; Waldman ID; Grove J; Als TD; Dalsgaard S; Ribasés M; Bybjerg-Grauholm J; Bækvad-Hansen M; Werge T; Nordentoft M; Mors O; Mortensen PB; ADHD Working Group of the Psychiatric Genomics Con; Cormand B; Hougaard DM; Neale BM; Franke B; Faraone SV; Børglum AD
Journal article: LANCET PSYCHIATRY. 2021;8(9):774-783

ADHD and physical conditions in adulthood in Sweden: a genetically informed register study

Du Rietz E; Brikell I; Butwicka A; Leone M; Chang Z; Cortese S; D'Onofrio BM; Hartman CA; Lichtenstein P; Faraone SV; Kuja-Halkola R; Larsson H
Article: BRITISH JOURNAL OF PSYCHIATRY. 2021;218(1):35-42

Overlap between attention-deficit hyperactivity disorder and neurodevelopmental, externalising and internalising disorders: separating unique from general psychopathology effects.

Du Rietz E; Pettersson E; Brikell I; Ghirardi L; Chen Q; Hartman C; Lichtenstein P; Larsson H; Kuja-Halkola R
Article: MOLECULAR PSYCHIATRY. 2020;25(8):1809-1821

The contribution of common genetic risk variants for ADHD to a general factor of childhood psychopathology.

Brikell I; Larsson H; Lu Y; Pettersson E; Chen Q; Kuja-Halkola R; Karlsson R; Lahey BB; Lichtenstein P; Martin J
Article: ADDICTION. 2020;115(7):1368-1377

Genetic liability to ADHD and substance use disorders in individuals with ADHD.

Wimberley T; Agerbo E; Horsdal HT; Ottosen C; Brikell I; Als TD; Demontis D; Børglum AD; Nordentoft M; Mors O; Werge T; Hougaard D; Bybjerg-Grauholm J; Hansen MB; Mortensen PB; Thapar A; Riglin L; Langley K; Dalsgaard S
Article: JAMA PSYCHIATRY. 2020;77(2):155-164

Incidence Rates and Cumulative Incidences of the Full Spectrum of Diagnosed Mental Disorders in Childhood and Adolescence.

Dalsgaard S; Thorsteinsson E; Trabjerg BB; Schullehner J; Plana-Ripoll O; Brikell I; Wimberley T; Thygesen M; Madsen KB; Timmerman A; Schendel D; McGrath JJ; Mortensen PB; Pedersen CB
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s115

S3ADHD DIAGNOSTIC & GENETIC HETEROGENEITY IN THE IPSYCH CASE-COHORT STUDY

LaBianca S; Brikell I; Helenius D; Schork A; Dalsgaard S; Werge T
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s90-s91

56 GENETICS OF ADHD DRUG TREATMENT RESPONSE IN OVER 13,000 ADHD CASES

Brikell I; Wimberley MT; Agerbo E; Pedersen E; Vilhjalmsson B; Schork A; Als T; Demontis D; Børglum A; Nordentoft M; Mors O; Werge T; Hougaard D; Mortensen PB; Dalsgaard S
Journal article: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:s51

ADHD AND MIGRAINE: INVESTIGATING SHARED GENETIC MECHANISM IN A POPULATION-BASED CASE-COHORT SAMPLE

Debost M; Agerbo E; Mortensen PB; Folkman-Hansen T; Dalsgaard S; Brikell I
Article: EPILEPSIA. 2019;60(2):284-293

Medication treatment for attention-deficit/hyperactivity disorder and the risk of acute seizures in individuals with epilepsy.

Brikell I; Chen Q; Kuja-Halkola R; D'Onofrio BM; Wiggs KK; Lichtenstein P; Almqvist C; Quinn PD; Chang Z; Larsson H
Article: JAMA NETWORK OPEN. 2019;2(1):e186606

Association of Prenatal Exposure to Valproate and Other Antiepileptic Drugs With Risk for Attention-Deficit/Hyperactivity Disorder in Offspring.

Christensen J; Pedersen L; Sun Y; Dreier JW; Brikell I; Dalsgaard S
Article: BIOLOGICAL PSYCHIATRY. 2018;83(12):1044-1053

A Genetic Investigation of Sex Bias in the Prevalence of Attention-Deficit/Hyperactivity Disorder.

Martin J; Walters RK; Demontis D; Mattheisen M; Lee SH; Robinson E; Brikell I; Ghirardi L; Larsson H; Lichtenstein P; Eriksson N; 23andMe Research Team; Psychiatric Genomics Consortium: ADHD Subgroup; iPSYCH–Broad ADHD Workgroup; Werge T; Mortensen PB; Pedersen MG; Mors O; Nordentoft M; Hougaard DM; Bybjerg-Grauholm J; Wray NR; Franke B; Faraone SV; O'Donovan MC; Thapar A; Børglum AD; Neale BM
Article: NEUROLOGY. 2018;90(13):e1104-e1110

Attention-deficit/hyperactivity disorder medication and seizures.

Wiggs KK; Chang Z; Quinn PD; Hur K; Gibbons R; Dunn D; Brikell I; Larsson H; D'Onofrio BM
Article: MOLECULAR PSYCHIATRY. 2018;23(2):257-262

The familial co-aggregation of ASD and ADHD: a register-based cohort study.

Ghirardi L; Brikell I; Kuja-Halkola R; Freitag CM; Franke B; Asherson P; Lichtenstein P; Larsson H
Article: BIOLOGICAL PSYCHIATRY. 2018;83(2):173-180

Familial Liability to Epilepsy and Attention-Deficit/Hyperactivity Disorder: A Nationwide Cohort Study.

Brikell I; Ghirardi L; D'Onofrio BM; Dunn DW; Almqvist C; Dalsgaard S; Kuja-Halkola R; Larsson H
Article: EUROPEAN CHILD & ADOLESCENT PSYCHIATRY. 2017;26(7):857-867

Predictive validity of parent- and self-rated ADHD symptoms in adolescence on adverse socioeconomic and health outcomes.

Du Rietz E; Kuja-Halkola R; Brikell I; Jangmo A; Sariaslan A; Lichtenstein P; Kuntsi J; Larsson H
Article: JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY. 2017;58(3):231-239

Familial aggregation of attention-deficit/hyperactivity disorder.

Chen Q; Brikell I; Lichtenstein P; Serlachius E; Kuja-Halkola R; Sandin S; Larsson H
Article: JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY. 2016;55(10):886-895

Relative Immaturity in Childhood and Attention-Deficit/Hyperactivity Disorder Symptoms From Childhood to Early Adulthood: Exploring Genetic and Environmental Overlap Across Development.

Brikell I; Kuja-Halkola R; Larsson J-O; Lahey BB; Kuntsi J; Lichtenstein P; Rydelius P-A; Larsson H
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Alla övriga publikationer

Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2023;147:105076

The association between type 2 diabetes and attention- deficit/hyperactivity disorder: A systematic review, meta-analysis, and population-based sibling study.

Garcia-Argibay M; Li L; Du Rietz E; Zhang L; Yao H; Jendle J; Ramos-Quiroga JA; Ribasés M; Chang Z; Brikell I; Cortese S; Larsson H
Preprint: MEDRXIV. 2022

Associations between attention-deficit hyperactivity disorder genetic liability and ICD-10 medical conditions in adults: Utilizing electronic health records in a Phenome-Wide Association Study

Haan E; Krebs K; Võsa U; Brikell I; Larsson H; Lehto K; Estonian Biobank Research Team
Preprint: MEDRXIV. 2022

Multi-PGS enhances polygenic prediction: weighting 937 polygenic scores

Albiñana C; Zhu Z; Schork AJ; Ingason A; Aschard H; Brikell I; Bulik CM; Petersen LV; Agerbo E; Grove J; Nordentoft M; Hougaard DM; Werge T; Børglum AD; Mortensen PB; McGrath JJ; Neale BM; Privé F; Vilhjálmsson BJ
Corrigendum: TRANSLATIONAL PSYCHIATRY. 2022;12(1):166

Correction: The role of ADHD genetic risk in mid-to-late life somatic health conditions.

Garcia-Argibay M; du Rietz E; Lu Y; Martin J; Haan E; Lehto K; Bergen SE; Lichtenstein P; Larsson H; Brikell I
Review: NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS. 2022;132:1157-1180

Non-mental diseases associated with ADHD across the lifespan: Fidgety Philipp and Pippi Longstocking at risk of multimorbidity?

Kittel-Schneider S; Arteaga-Henriquez G; Vasquez AA; Asherson P; Banaschewski T; Brikell I; Buitelaar J; Cormand B; Faraone SV; Freitag CM; Ginsberg Y; Haavik J; Hartman CA; Kuntsi J; Larsson H; Matura S; McNeill RV; Ramos-Quiroga JA; Ribases M; Romanos M; Vainieri I; Franke B; Reif A
Book chapter: TWIN RESEARCH FOR EVERYONE. 2022;p. 277-294

Chapter 17 Childhood development of psychiatric disorders and related traits

Brikell I; Lichtenstein P; Larsson H
Review: PSYCHOLOGICAL MEDICINE. 2021;51(13):2274-2286

Insights into attention-deficit/hyperactivity disorder from recent genetic studies.

Brikell I; Burton C; Mota NR; Martin J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E196

ASSOCIATIONS AND INTERACTIONS OF ADHD POLYGENIC LIABILITY WITH PRE-AND PERINATAL, SOMATIC, AND PSYCHOSOCIAL RISK-FACTORS IN THE DEVELOPMENT OF ADHD - A NATIONWIDE STUDY

Brikell I; Wimberley MT; Albinana C; Vilhjalmsson B; Agerbo E; Borglum A; Demontis D; Schork A; LaBianca S; Mortensen PB; Petersen L; Dalsgaard S
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2021;51:E148-E149

ADHD AND MIGRAINE - FAMILIAL AND POLYGENIC ASSOCIATION'S IN A NATIONWIDE REPRESENTATIVE SAMPLE

Brikell I; Semark BD; Larsen JT; Petersen L; Albinana C; Vilhjalmsson B; Demontis D; Borglum A; Grove J; Agerbo E; Mortensen PB; Hansen TF; Dalsgaard S
Preprint: MEDRXIV. 2021

Interplay of ADHD polygenic liability with birth-related, somatic and psychosocial factors in ADHD - a nationwide study

Brikell I; Wimberley T; Albiñana C; Vilhjálmsson BJ; Agerbo E; Børglum AD; Demontis D; Schork AJ; LaBianca S; Werge T; Hougaard DM; Nordentoft M; Mors O; Mortensen PB; Petersen LV; Dalsgaard S
Preprint: MEDRXIV. 2021

Polygenic profiles define aspects of clinical heterogeneity in ADHD

LaBianca S; Brikell I; Helenius D; Loughnan R; Mefford J; Palmer CE; Walker R; Gådin JR; Krebs M; Appadurai V; Vaez M; Agerbo E; Pedersen MG; Børglum AD; Hougaard DM; Mors O; Nordentoft M; Mortensen PB; Kendler KS; Jernigan TL; Geschwind DH; Ingason A; Dahl AW; Zaitlen N; Dalsgaard S; Werge TM; Schork AJ
Letter: JAMA NETWORK OPEN. 2021;4(1):e2033478

Public Mobility and Social Media Attention in Response to COVID-19 in Sweden and Denmark.

Zhang L; Brikell I; Dalsgaard S; Chang Z
Book chapter: THE CAMBRIDGE HANDBOOK OF RESEARCH METHODS IN CLINICAL PSYCHOLOGY. 2020;p. 219-229

Quantitative Genetic Research Strategies for Studying Gene-Environment Interplay in the Development of Child and Adolescent Psychopathology

Brikell I; Larsson H
Preprint: MEDRXIV. 2020

ADHD is more closely linked to neurodevelopmental than externalizing and internalizing disorders: A genetically informed multivariate Swedish population study

Rietz ED; Pettersson E; Brikell I; Ghirardi L; Chen Q; Hartman C; Lichtenstein P; Larsson H; Kuja-Halkola R
Conference publication: BEHAVIOR GENETICS. 2020;50(6):452

Associations between ADHD and medical disorders in adulthood: a large-scale genetically informed Swedish register study

Du Rietz E; Brikell I; Butwicka A; Kuja-Halkola R; Larsson H
Preprint: BIORXIV. 2019

Genetic Association Study of Childhood Aggression across raters, instruments and age

Ip H; van der Laan C; Krapohl E; Brikell I; Cristina S-M; Nolte I; St Pourcain B; Bolhuis K; Palviainen T; Zafarmand H; Colodro-Conde L; Gordon S; Zayats T; Aliev F; Jiang C; Wang C; Saunders G; Karhunen V; Hammerschlag A; Adkins D; Border R; Peterson R; Prinz J; Thiering E; Seppälä I; Natàlia V-T; Ahluwalia T; Day F; Hottenga J-J; Allegrini A; Rimfeld K; Chen Q; Lu Y; Martin J; Soler Artigas M; Rovira P; Bosch R; Español G; Ramos Quiroga JA; Neumann A; Ensink J; Grasby K; Morosoli J; Tong X; Marrington S; Middeldorp C; Scott J; Vinkhuyzen A; Shabalin A; Corley R; Evans L; Sugden K; Alemany S; Sass L; Vinding R; Ruth K; Tyrrell J; Davies G; Ehli E; Hagenbeek F; De Zeeuw E; Van Beijsterveldt TCEM; Larsson H; Snieder H; Verhulst F; Amin N; Whipp A; Korhonen T; Vuoksimaa E; Rose R; Uitterlinden A; Heath A; Madden P; Haavik J; Harris J; Helgeland Ø; Johansson S; Knudsen GP; Njolstad PR; Lu Q; Rodriguez A; Henders A; Mamun A; Najman J; Brown S; Hopfer C; Krauter K; Reynolds C; Smolen A; Stallings M; Wadsworth S; Wall T; Silberg J; Miller A; Keltikangas-Järvinen L; Hakulinen C; Pulkki-Råback L; Havdahl A; Magnus P; Raitakari O; Perry JRB; Llop S; Lopez-Espinosa M-J; Bønnelykke K; Bisgaard H; Sunyer J; Lehtimäki T; Arseneault L; Standl M; Heinrich J; Boden J; Pearson J; Horwood J; Kennedy M; Poulton R; Eaves L; Maes H; Hewitt J; Copeland W; Costello E; Williams G; Wray N; Järvelin M-R; McGue M; Iacono W; Caspi A; Moffitt T; Whitehouse A; Pennell C; Klump K; Burt A; Dick D; Reichborn-Kjennerud T; Martin N; Medland S; Vrijkotte T; Kaprio J; Tiemeier H; Davey Smith G; Hartman C; Oldehinkel A; Casas M; Ribasés M; Lichtenstein P; Lundström S; Plomin R; Bartels M; Nivard M; Boomsma D
Published conference paper: JAMA PSYCHIATRY. 2019;76(3):280-289

Association of Genetic Risk Factors for Psychiatric Disorders and Traits of These Disorders in a Swedish Population Twin Sample.

Taylor MJ; Martin J; Lu Y; Brikell I; Lundström S; Larsson H; Lichtenstein P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:1043

ASSOCIATIONS OF POLYGENIC RISKS FOR CHILDHOOD NEUROPSYCHIATRIC DISORDERS WITH SOMATIC HEALTH PROBLEMS ACROSS THE LIFESPAN

Brikell I; Yi L; Martin J; Lichtenstein P; Larsson H
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S723-S724

THE MANIFESTATION OF GENETIC RISK FOR ATTENTION DEFICIT HYPERACTIVITY DISORDER IN FEMALES AND MALES IN THE GENERAL POPULATION

Martin J; Brikell I; Ghirardi L; Taylor M; Riglin L; Eyre O; Larsson H; Thapar A; Neale B; Lichtenstein P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S753

GENETIC EVIDENCE FOR PSYCHIATRIC DISORDERS AS THE EXTREME END OF A CONTINUUM OF POPULATION TRAITS

Martin J; Taylor M; Yi L; Brikell I; Lundstrom S; Lichtenstein P
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S811

COMMON GENETIC RISK VARIANTS FOR ADHD CONTRIBUTE TO CHILDHOOD NEURODEVELOPMENTAL AND EXTERNALIZING TRAITS IN THE POPULATION

Brikell I; Larsson H; Yi L; Petterson E; Chen Q; Kuja-Halkola R; Karlsson R; Lichtenstein P; Martin J
Conference publication: EUROPEAN NEUROPSYCHOPHARMACOLOGY. 2019;29:S758

HERITABILITY OF ATTENTION-DEFICIT HYPERACTIVITY DISORDER ACROSS THE LIFESPAN

Brikell I; Kuja-Halkola R; Larsson H
Conference publication: BEHAVIOR GENETICS. 2019;49(6):531

Genetic and environmental influences on the association between ADHD and school achievement

Jangmo A; Kuja-Halkola R; Brikell I; Feldman I; Almqvist C; Bulik C; Larsson H
Conference publication: BEHAVIOR GENETICS. 2019;49(6):514

The contribution of ADHD genetic risk to somatic health in late life

Brikell I; Lu Y; Martin J; Larsson H; Lichtenstein P
Conference publication: BEHAVIOR GENETICS. 2019;49(6):499

Characterizing shared genetic risks between ADHD and other phenotypes

Martin J; Brikell I; Du Rietz E; Carey C; Neale B
Conference publication: BEHAVIOR GENETICS. 2019;49(6):513

Phenotypic, genetic and environmental correlations between diagnosed ADHD, neurodevelopmental, internalizing and externalizing disorders

Du Rietz E; Ghirardi L; Brikell I; Hartman C; Larsson H; Kuja-Halkola R
Thesis / dissertation: 2018

ADHD, epilepsy, and related childhood psychopathology : understanding shared genetic risk, developmental trajectories, and pharmacological treatment safety

Brikell, Isabell
Conference publication: BEHAVIOR GENETICS. 2018;48(6):524

Genetics of ADHD dimensions. Genome-wide association analyses of inattention and hyperactivity/impulsivity

Zayats T; English G; Allegrini A; Rimfeld K; Burton C; Xiao B; Martin J; Lu Y; Brikell I; Nivard M; Crosbie J; Arnold P; Schachar R; Greven C; Johansson S; Lundstrom S; Larsson H; Lichtenstein P; Boomsma D; Medland S; Haavik J; Neale B
Conference publication: BEHAVIOR GENETICS. 2018;48(6):480-481

Multivariate GWAMA in over 500k observations on aggressive behavior and ADHD symptoms

Ip H; Zafarmand H; Wedow R; St Pourcain B; Alemany S; Vilor-tejedor N; Lundstrom S; Lu Y; Chen Q; Brikell I; Martin J; Sugden K; Prinz J; Palviainen T; Loukola A; Korhonen T; Vuoksimaa E; Neumann A; Bolhuis K; Thiering E; Standl M; Wills A; Corley R
Review: AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS. 2015;168(6):406-413

Heritability of attention-deficit hyperactivity disorder in adults.

Brikell I; Kuja-Halkola R; Larsson H
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Anställningar

Biträdande Lektor, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2024-2029
Forskningssamordnare, Medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2020-2023

Examina och utbildning

Medicine Doktorsexamen, Institutionen för medicinsk epidemiologi och biostatistik, Karolinska Institutet, 2018

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