Indranil Sinha

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CHILDREN-BASEL. 2023;10(6):966

The Applicability of a 2-Transcript Signature to Identify Bacterial Infections in Children with Febrile Neutropenia.

Aasa J; Tiselius E; Sinha I; Edman G; Wahlund M; Hedengren SS; Nilsson A; Berggren A
Article: EJHAEM. 2023;4(1):115-124

Malignant DFFB isoform switching promotes leukemia survival in relapse pediatric T-cell acute lymphoblastic leukemia.

Enlund S; Sinha I; Amor AR; Fard SS; Tamm EP; Jiang Q; Lundin V; Nilsson A; Holm F
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2023;11:1060537

Molecular and epigenetic alterations in normal and malignant myelopoiesis in human leukemia 60 (HL60) promyelocytic cell line model.

Basu J; Madhulika S; Murmu KC; Mohanty S; Samal P; Das A; Mahapatra S; Saha S; Sinha I; Prasad P
Article: FRONTIERS IN ENDOCRINOLOGY. 2022;13:930227

ERα and ERβ Homodimers in the Same Cellular Context Regulate Distinct Transcriptomes and Functions.

Song D; He H; Indukuri R; Huang Z; Stepanauskaite L; Sinha I; Haldosén L-A; Zhao C; Williams C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(40):e2109123118

High-dimensional profiling reveals phenotypic heterogeneity and disease-specific alterations of granulocytes in COVID-19.

Lourda M; Dzidic M; Hertwig L; Bergsten H; Palma Medina LM; Sinha I; Kvedaraite E; Chen P; Muvva JR; Gorin J-B; Cornillet M; Emgård J; Moll K; García M; Maleki KT; Klingström J; Michaëlsson J; Flodström-Tullberg M; Brighenti S; Buggert M; Mjösberg J; Malmberg K-J; Sandberg JK; Henter J-I; Folkesson E; Gredmark-Russ S; Sönnerborg A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Björkström NK; Svensson M; Ponzetta A; Norrby-Teglund A; Chambers BJ; Karolinska KI/K COVID-19 Study Group
Article: ANTIOXIDANTS. 2021;10(7):1070

Dehydro-Tocotrienol-β Counteracts Oxidative-Stress-Induced Diabetes Complications in db/db Mice.

Dallner G; Bentinger M; Hussain S; Sinha I; Yang J; Schwank-Xu C; Zheng X; Swiezewska E; Brismar K; Valladolid-Acebes I; Tekle M
Article: CANCER LETTERS. 2021;506:23-34

Blocking Fra-1 sensitizes triple-negative breast cancer to PARP inhibitor.

Song D; He H; Sinha I; Hases L; Yan F; Archer A; Haldosen L-A; Zhao C; Williams C
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(6):e2018587118

Major alterations in the mononuclear phagocyte landscape associated with COVID-19 severity.

Kvedaraite E; Hertwig L; Sinha I; Ponzetta A; Hed Myrberg I; Lourda M; Dzidic M; Akber M; Klingström J; Folkesson E; Muvva JR; Chen P; Gredmark-Russ S; Brighenti S; Norrby-Teglund A; Eriksson LI; Rooyackers O; Aleman S; Strålin K; Ljunggren H-G; Ginhoux F; Björkström NK; Henter J-I; Svensson M; Karolinska KI/K COVID-19 Study Group
Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(15):5305

The Feasibility of Host Transcriptome Profiling as a Diagnostic Tool for Microbial Etiology in Childhood Cancer Patients with Febrile Neutropenia.

Wahlund M; Sinha I; Broliden K; Saghafian-Hedengren S; Nilsson A; Berggren A
Article: CELL REPORTS. 2020;31(5):107601

Srebf1 Controls Midbrain Dopaminergic Neurogenesis.

Toledo EM; Yang S; Gyllborg D; van Wijk KE; Sinha I; Varas-Godoy M; Grigsby CL; Lönnerberg P; Islam S; Steffensen KR; Linnarsson S; Arenas E
Article: MOLECULAR METABOLISM. 2019;25:159-167

Epigenetic regulation of diabetogenic adipose morphology.

Kerr AG; Sinha I; Dadvar S; Arner P; Dahlman I
Article: ONCOGENE. 2019;38(28):5725-5738

Endogenous interaction profiling identifies DDX5 as an oncogenic coactivator of transcription factor Fra-1.

He H; Song D; Sinha I; Hessling B; Li X; Haldosen L-A; Zhao C
Article: ONCOGENE. 2018;37(19):2586-2600

c-Jun/AP-1 overexpression reprograms ERα signaling related to tamoxifen response in ERα-positive breast cancer.

He H; Sinha I; Fan R; Haldosen L-A; Yan F; Zhao C; Dahlman-Wright K
Article: SCIENTIFIC REPORTS. 2017;7(1):10152

Epigenetic Regulation of PLIN 1 in Obese Women and its Relation to Lipolysis.

Bialesova L; Kulyté A; Petrus P; Sinha I; Laurencikiene J; Zhao C; Wright KD; Arner P; Dahlman I
Article: DIABETOLOGIA. 2016;59(11):2393-2405

The epigenetic signature of systemic insulin resistance in obese women.

Arner P; Sahlqvist A-S; Sinha I; Xu H; Yao X; Waterworth D; Rajpal D; Loomis AK; Freudenberg JM; Johnson T; Thorell A; Näslund E; Ryden M; Dahlman I
Article: CANCER RESEARCH. 2016;76(19):5634-5646

Estrogen Receptor α Promotes Breast Cancer by Reprogramming Choline Metabolism.

Jia M; Andreassen T; Jensen L; Bathen TF; Sinha I; Gao H; Zhao C; Haldosen L-A; Cao Y; Girnita L; Moestue SA; Dahlman-Wright K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(29):15169-15184

Peroxisome Proliferator-activated Receptor γ Coactivator-1 α Isoforms Selectively Regulate Multiple Splicing Events on Target Genes.

Martínez-Redondo V; Jannig PR; Correia JC; Ferreira DMS; Cervenka I; Lindvall JM; Sinha I; Izadi M; Pettersson-Klein AT; Agudelo LZ; Gimenez-Cassina A; Brum PC; Dahlman-Wright K; Ruas JL
Article: ONCOGENE. 2016;35(15):1955-1964

RING finger protein 31 promotes p53 degradation in breast cancer cells.

Zhu J; Zhao C; Zhuang T; Jonsson P; Sinha I; Williams C; Strömblad S; Dahlman-Wright K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2016;291(10):5068-5079

AP-1 Is a Key Regulator of Proinflammatory Cytokine TNFα-mediated Triple-negative Breast Cancer Progression.

Qiao Y; He H; Jonsson P; Sinha I; Zhao C; Dahlman-Wright K
Article: MOLECULAR METABOLISM. 2016;5(3):171-183

Altered DNA methylation of glycolytic and lipogenic genes in liver from obese and type 2 diabetic patients.

Kirchner H; Sinha I; Gao H; Ruby MA; Schönke M; Lindvall JM; Barrès R; Krook A; Näslund E; Dahlman-Wright K; Zierath JR
Article: SCIENTIFIC REPORTS. 2016;6:18617

Hippocampal Transcriptome Profile of Persistent Memory Rescue in a Mouse Model of THRA1 Mutation-Mediated Resistance to Thyroid Hormone.

Wang Y; Fisahn A; Sinha I; Nguyen DP; Sterzenbach U; Lallemend F; Hadjab S
Article: OBESITY. 2016;24(1):250-261

Differential methylation in inflammation and type 2 diabetes genes in siblings born before and after maternal bariatric surgery.

Berglind D; Müller P; Willmer M; Sinha I; Tynelius P; Näslund E; Dahlman-Wright K; Rasmussen F
Article: MOLECULAR METABOLISM. 2015;4(12):891-902

Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism.

Correia JC; Massart J; de Boer JF; Porsmyr-Palmertz M; Martínez-Redondo V; Agudelo LZ; Sinha I; Meierhofer D; Ribeiro V; Björnholm M; Sauer S; Dahlman-Wright K; Zierath JR; Groen AK; Ruas JL
Article: INTERNATIONAL JOURNAL OF OBESITY. 2015;39(6):910-919

The fat cell epigenetic signature in post-obese women is characterized by global hypomethylation and differential DNA methylation of adipogenesis genes.

Dahlman I; Sinha I; Gao H; Brodin D; Thorell A; Rydén M; Andersson DP; Henriksson J; Perfilyev A; Ling C; Dahlman-Wright K; Arner P
Article: GENOME RESEARCH. 2015;25(6):872-883

A nucleosome turnover map reveals that the stability of histone H4 Lys20 methylation depends on histone recycling in transcribed chromatin.

Svensson JP; Shukla M; Menendez-Benito V; Norman-Axelsson U; Audergon P; Sinha I; Tanny JC; Allshire RC; Ekwall K
Article: CLINICAL EPIGENETICS. 2015;7(1):93

The epigenetic signature of subcutaneous fat cells is linked to altered expression of genes implicated in lipid metabolism in obese women.

Arner P; Sinha I; Thorell A; Rydén M; Dahlman-Wright K; Dahlman I
Article: CANCER RESEARCH. 2014;74(14):3983-3994

Genome-wide profiling of AP-1-regulated transcription provides insights into the invasiveness of triple-negative breast cancer.

Zhao C; Qiao Y; Jonsson P; Wang J; Xu L; Rouhi P; Sinha I; Cao Y; Williams C; Dahlman-Wright K
Article: PLOS ONE. 2013;8(8):e72409

Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells.

Abdelhady S; Kitambi SS; Lundin V; Aufschnaiter R; Sekyrova P; Sinha I; Lundgren KT; Castelo-Branco G; Linnarsson S; Wedlich-Söldner R; Teixeira A; Andäng M
Article: EMBO JOURNAL. 2012;31(18):3718-3729

Positional differences of axon growth rates between sensory neurons encoded by Runx3.

Lallemend F; Sterzenbach U; Hadjab-Lallemend S; Aquino JB; Castelo-Branco G; Sinha I; Villaescusa JC; Levanon D; Wang Y; Franck MCM; Kharchenko O; Adameyko I; Linnarsson S; Groner Y; Turner E; Ernfors P
Article: EPIGENOMICS. 2010;2(3):377-393

Genome-wide mapping of histone modifications and mass spectrometry reveal H4 acetylation bias and H3K36 methylation at gene promoters in fission yeast.

Sinha I; Buchanan L; Rönnerblad M; Bonilla C; Durand-Dubief M; Shevchenko A; Grunstein M; Stewart AF; Ekwall K
Article: EMBO JOURNAL. 2007;26(10):2477-2488

Specific functions for the fission yeast Sirtuins Hst2 and Hst4 in gene regulation and retrotransposon silencing.

Durand-Dubief M; Sinha I; Fagerström-Billai F; Bonilla C; Wright A; Grunstein M; Ekwall K
Article: MOLECULAR CELL. 2006;22(2):169-178

Genome-wide occupancy profile of mediator and the Srb8-11 module reveals interactions with coding regions.

Zhu X; Wirén M; Sinha I; Rasmussen NN; Linder T; Holmberg S; Ekwall K; Gustafsson CM
Article: CHROMOSOME RESEARCH. 2006;14(1):95-105

Genome-wide patterns of histone modifications in fission yeast.

Sinha I; Wirén M; Ekwall K
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2005;334(4):1149-1158

Global analysis of altered gene expression during morphogenesis of Candida albicans in vitro.

Singh V; Sinha I; Sadhale PP
Article: EMBO JOURNAL. 2005;24(16):2906-2918

Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast.

Wirén M; Silverstein RA; Sinha I; Walfridsson J; Lee H-M; Laurenson P; Pillus L; Robyr D; Grunstein M; Ekwall K
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Published paper: BRITISH JOURNAL OF SURGERY. 2019;106(5):563-573

Autologous fat transplantation alters gene expression patterns related to inflammation and hypoxia in the irradiated human breast.

Lindegren A; Schultz I; Sinha I; Cheung L; Khan AA; Tekle M; Wickman M; Halle M
Corrigendum: DIABETOLOGIA. 2016;59(12):2728

Erratum to: The epigenetic signature of systemic insulin resistance in obese women.

Arner P; Sahlqvist A-S; Sinha I; Xu H; Yao X; Waterworth D; Rajpal D; Loomis AK; Freudenberg JM; Johnson T; Thorell A; Näslund E; Ryden M; Dahlman I

Anställningar

Anknuten till Forskning, Kvinnors och barns hälsa, Karolinska Institutet, 2024-2024
Bioinformatiker, Kvinnors och barns hälsa, Karolinska Institutet, 2020-2024

Examina och utbildning

Filosofie Doktorsexamen, Institutionen för biovetenskaper och näringslära, Karolinska Institutet, 2010

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