Flavio Ballante

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Journal article: FRONTIERS IN MOLECULAR BIOSCIENCES. 2023;10:1264773

Modified N-acyl-L-homoserine lactone compounds abrogate Las-dependent quorum-sensing response in human pathogen Pseudomonas aeruginosa.

Ballante F; Turkina MV; Ntzouni M; Magnusson K-E; Vikström E
Journal article: PHARMACOLOGICAL REVIEWS. 2021;73(4):527-565

Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?

Ballante F; Kooistra AJ; Kampen S; de Graaf C; Carlsson J
Journal article: PLOS COMPUTATIONAL BIOLOGY. 2021;17(5):e1008936

Can molecular dynamics simulations improve the structural accuracy and virtual screening performance of GPCR models?

Kapla J; Rodríguez-Espigares I; Ballante F; Selent J; Carlsson J
Journal article: JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY. 2021;36(1):34-47

Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines.

Nencetti S; Cuffaro D; Nuti E; Ciccone L; Rossello A; Fabbi M; Ballante F; Ortore G; Carbotti G; Campelli F; Banti I; Gangemi R; Marshall GR; Orlandini E
Journal article: JOURNAL OF MEDICINAL CHEMISTRY. 2020;63(2):613-620

Docking Finds GPCR Ligands in Dark Chemical Matter.

Ballante F; Rudling A; Zeifman A; Luttens A; Vo DD; Irwin JJ; Kihlberg J; Brea J; Loza MI; Carlsson J
Journal article: ACS PHARMACOLOGY AND TRANSLATIONAL SCIENCE. 2018;1(2):119-133

Structural Characterization of Agonist Binding to Protease-Activated Receptor 2 through Mutagenesis and Computational Modeling.

Kennedy AJ; Ballante F; Johansson JR; Milligan G; Sundström L; Nordqvist A; Carlsson J
Journal article: DRUG DEVELOPMENT RESEARCH. 2017;78(6):245-267

Limiting Assumptions in the Design of Peptidomimetics.

Marshall GR; Ballante F
Journal article: BIOORGANIC & MEDICINAL CHEMISTRY. 2017;25(7):2105-2132

Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy.

Ballante F; Reddy DR; Zhou NJ; Marshall GR
Journal article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2017;127:531-553

Design and synthesis of benzodiazepine analogs as isoform-selective human lysine deacetylase inhibitors.

Reddy DR; Ballante F; Zhou NJ; Marshall GR
Journal article: JOURNAL OF MEDICINAL CHEMISTRY. 2016;59(4):1613-1633

Design and Synthesis of Simplified Largazole Analogues as Isoform-Selective Human Lysine Deacetylase Inhibitors.

Reddy DN; Ballante F; Chuang T; Pirolli A; Marrocco B; Marshall GR
Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2016;56(1):54-72

An Automated Strategy for Binding-Pose Selection and Docking Assessment in Structure-Based Drug Design.

Ballante F; Marshall GR
Journal article: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN. 2015;29(8):757-776

Vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors: development and validation of predictive 3-D QSAR models through extensive ligand- and structure-based approaches.

Ragno R; Ballante F; Pirolli A; Wickersham RB; Patsilinakos A; Hesse S; Perspicace E; Kirsch G
Journal article: JOURNAL OF MEDICINAL CHEMISTRY. 2014;57(12):5212-5225

Exploring the role of 2-chloro-6-fluoro substitution in 2-alkylthio-6-benzyl-5-alkylpyrimidin-4(3H)-ones: effects in HIV-1-infected cells and in HIV-1 reverse transcriptase enzymes.

Rotili D; Tarantino D; Nawrozkij MB; Babushkin AS; Botta G; Marrocco B; Cirilli R; Menta S; Badia R; Crespan E; Ballante F; Ragno R; Esté JA; Maga G; Mai A
Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2014;54(3):970-977

Hsp90 inhibitors, part 2: combining ligand-based and structure-based approaches for virtual screening application.

Caroli A; Ballante F; Wickersham RB; Corelli F; Ragno R
Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2014;54(3):956-969

Hsp90 inhibitors, part 1: definition of 3-D QSAutogrid/R models as a tool for virtual screening.

Ballante F; Caroli A; Wickersham RB; Ragno R
Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2013;53(6):1463-1474

Pharmacophore assessment through 3-D QSAR: evaluation of the predictive ability on new derivatives by the application on a series of antitubercular agents.

Friggeri L; Ballante F; Ragno R; Musmuca I; De Vita D; Manetti F; Biava M; Scipione L; Di Santo R; Costi R; Feroci M; Tortorella S
Journal article: EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. 2013;63:765-781

Design, synthesis and biological evaluation of new classes of thieno[3,2-d]pyrimidinone and thieno[1,2,3]triazine as inhibitor of vascular endothelial growth factor receptor-2 (VEGFR-2).

Perspicace E; Jouan-Hureaux V; Ragno R; Ballante F; Sartini S; La Motta C; Da Settimo F; Chen B; Kirsch G; Schneider S; Faivre B; Hesse S
Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2012;52(8):2215-2235

Histone deacetylase inhibitors: structure-based modeling and isoform-selectivity prediction.

Silvestri L; Ballante F; Mai A; Marshall GR; Ragno R
Journal article: JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN. 2012;26(8):907-919

Comprehensive model of wild-type and mutant HIV-1 reverse transciptases.

Ballante F; Musmuca I; Marshall GR; Ragno R
Journal article: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 2012;52(6):1674-1685

3-D QSAutogrid/R: an alternative procedure to build 3-D QSAR models. Methodologies and applications.

Ballante F; Ragno R
Journal article: JOURNAL OF MEDICINAL CHEMISTRY. 2012;55(7):3558-3562

2-(Alkyl/aryl)amino-6-benzylpyrimidin-4(3H)-ones as inhibitors of wild-type and mutant HIV-1: enantioselectivity studies.

Rotili D; Samuele A; Tarantino D; Ragno R; Musmuca I; Ballante F; Botta G; Morera L; Pierini M; Cirilli R; Nawrozkij MB; Gonzalez E; Clotet B; Artico M; Esté JA; Maga G; Mai A
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Conference publication: 2023

Exploring the morphology of the host cell to open new possibilities for drug repurposing in viral infections

Tampere M; Kalman A; Rietdijk J; Axelsson H; Njenda D; Kaimal JM; Lapins M; Ballante F; Le TH; Bäckström A; Seashore-Ludlow B; Lundberg E; Spjuth O; Carreras-Puigvert J; Stadler C; Östling P
Book: METHODS IN MOLECULAR BIOLOGY. 2021

Protein-Ligand Interactions and Drug Design
Book chapter: METHODS IN MOLECULAR BIOLOGY. 2018;p. 67-88

Protein-Ligand Docking in Drug Design: Performance Assessment and Binding-Pose Selection.

Ballante F
Conference publication: AMINO ACIDS. 2013;45(3):567

Computational strategies to design new highly potential BSAO polyamine substrates

Ballante F; Tempera G; Agostinelli E; Ragno R

Anställningar

Senior Forskningsinfrastrukturspecialist, Medicinsk biokemi och biofysik, Karolinska Institutet, 2024-
Forskningsspecialist, Medicinsk biokemi och biofysik, Karolinska Institutet, 2022-2023
Researcher, Medicinal chemistry, Department of Cell and Molecular Biology, Uppsala University, 2017-2022

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