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Felix Haglund

Senior forskare

Om mig

Associate Professor of Experimental Pathology, Karolinska Institutet

Head of Molecular Cancer Diagnostics (Molecular Pathology), Karolinska University Hospital Solna

M.D. / Ph.D., Consultant Clinical Pathologist

 

Forskningsbeskrivning

- Precision cancer genomics

- Sarcoma genomics and biology

 

Recent publications:

Sarcoma Tumor Microenvironment. Tsagozis P, Gonzalez-Molina J, Georgoudaki AM, Lehti K, Carlson J, Lundqvist A, Haglund F, Ehnman M.Adv Exp Med Biol. 2020;1296:319-348. doi: 10.1007/978-3-030-59038-3_20. PMID: 34185302

Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing Sarcoma. Chen Y, Su H, Su Y, Zhang Y, Lin Y, Haglund F. Cancers (Basel). 2021 Jul 25;13(15):3736. doi: 10.3390/cancers13153736. PMID: 34359637

Follicular Helper T-Cell-Based Classification of Endometrial Cancer Promotes Precise Checkpoint Immunotherapy and Provides Prognostic Stratification. Chen Y, You S, Li J, Zhang Y, Kokaraki G, Epstein E, Carlson J, Huang WK, Haglund F. Front Immunol. 2022 Jan 7;12:788959. doi: 10.3389/fimmu.2021.788959. eCollection 2021 PMID: 35069566 

Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing Sarcoma. Chen Y, Su H, Su Y, Zhang Y, Lin Y, Haglund F. Cancers (Basel). 2021 Jul 25;13(15):3736. doi: 10.3390/cancers13153736.PMID: 34359637 Free PMC article.

TERT promoter mutation is an objective clinical marker for disease progression in chondrosarcoma. Zhang Y, Chen Y, Yang C, Seger N, Hesla AC, Tsagkozis P, Larsson O, Lin Y, Haglund F. Mod Pathol. 2021 Nov;34(11):2020-2027. doi: 10.1038/s41379-021-00848-0. Epub 2021 Jun 9. PMID: 34108637 

CD11c-CD8 Spatial Cross Presentation: A Novel Approach to Link Immune Surveillance and Patient Survival in Soft Tissue Sarcoma. Su Y, Tsagkozis P, Papakonstantinou A, Tobin NP, Gultekin O, Malmerfelt A, Ingelshed K, Neo SY, Lundquist J, Chaabane W, Nisancioglu MH, Leiss LW, Östman A, Bergh J, Sedimbi S, Lehti K, Lundqvist A, Stragliotto CL, Haglund F, Ehnman M.Cancers (Basel). 2021 Mar 9;13(5):1175. doi: 10.3390/cancers13051175.PMID: 33803245 

Clear-cell chondrosarcomas: Fine-needle aspiration cytology, radiological findings, and patient demographics of a rare entity. Zhang Y, Alagic Z, Tani E, Skorpil M, Tsagkozis P, Haglund F.Diagn Cytopathol. 2021 Jan;49(1):46-53. doi: 10.1002/dc.24582. Epub 2020 Aug 12.PMID: 32786062 

Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers. Yang C, Zhang Y, Chen Y, Ragaller F, Liu M, Corvigno S, Dahlstrand H, Carlson J, Chen Z, Näsman A, Waraky A, Lin Y, Larsson O, Haglund F.PLoS One. 2020 Jul 23;15(7):e0236291. doi: 10.1371/journal.pone.0236291. eCollection 2020.PMID: 32701997 

 

Transcriptome profiling of Ewing sarcomas - treatment resistance pathways and IGF-dependency. Chen Y, Hesla AC, Lin Y, Ghaderi M, Liu M, Yang C, Zhang Y, Tsagkozis P, Larsson O, Haglund F.Mol Oncol. 2020 May;14(5):1101-1117. doi: 10.1002/1878-0261.12655. Epub 2020 Mar 13.PMID: 32115849 

Utbildning

MD, Karolinska Institutet 2012

PhD, Karolinska Institutet 2013

Licenced physician 2014

Associate Progessor of Experimental Pathology, Karolinska Institutet 2019

Consultant Clinical Pathologist 2019

Akademiska priser och utmärkelser

Thesis of the Year, Swedish Association of Pathology 2014

Young Researcher Award, Euro Ewing Consortium 2018

 

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