Erdinc Sezgin

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Please visit the English version of the website [1] for details.
[1] https://staff.ki.se/people/erdsez?_ga=2.50627369.1066920700.1583140098-746479776.1550748706

Artiklar

Article: MOLECULAR SYSTEMS BIOLOGY. 2024;20(4):374-402

Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis.

Sommerauer C; Gallardo-Dodd CJ; Savva C; Hases L; Birgersson M; Indukuri R; Shen JX; Carravilla P; Geng K; Nørskov Søndergaard J; Ferrer-Aumatell C; Mercier G; Sezgin E; Korach-André M; Petersson C; Hagström H; Lauschke VM; Archer A; Williams C; Kutter C
Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2024;128(9):2154-2167

Quantifying Fluorescence Lifetime Responsiveness of Environment-Sensitive Probes for Membrane Fluidity Measurements.

Ragaller F; Sjule E; Urem YB; Schlegel J; El R; Urbancic D; Urbancic I; Blom H; Sezgin E
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2024;300(2):105649

A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.

Menon I; Sych T; Son Y; Morizumi T; Lee J; Ernst OP; Khelashvili G; Sezgin E; Levitz J; Menon AK
Article: NATURE COMMUNICATIONS. 2024;15(1):541

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis.

Drexhage LZ; Zhang S; Dupont M; Ragaller F; Sjule E; Cabezas-Caballero J; Deimel LP; Robertson H; Russell RA; Dushek O; Sezgin E; Karaji N; Sattentau QJ
Article: ACS APPLIED BIO MATERIALS. 2023;6(12):5746-5758

Protein-Decorated Microbubbles for Ultrasound-Mediated Cell Surface Manipulation.

Brans VA; Gray MD; Sezgin E; Stride EPJ
Journal article: BIOCONJUGATE CHEMISTRY. 2023;34(10):1923

Correction to Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells.

Sternstein C; Böhm T-M; Fink J; Meyr J; Lüdemann M; Krug M; Kriukov K; Gurdap CO; Sezgin E; Ebert R; Seibel J
Article: BIOCONJUGATE CHEMISTRY. 2023;34(7):1221-1233

Development of an Effective Functional Lipid Anchor for Membranes (FLAME) for the Bioorthogonal Modification of the Lipid Bilayer of Mesenchymal Stromal Cells.

Sternstein C; Böhm T-M; Fink J; Meyr J; Lüdemann M; Krug M; Kriukov K; Gurdap CO; Sezgin E; Ebert R; Seibel J
Article: NATURE BIOTECHNOLOGY. 2023;:1-4

High-throughput measurement of the content and properties of nano-sized bioparticles with single-particle profiler.

Sych T; Schlegel J; Barriga HMG; Ojansivu M; Hanke L; Weber F; Beklem Bostancioglu R; Ezzat K; Stangl H; Plochberger B; Laurencikiene J; El Andaloussi S; Fürth D; Stevens MM; Sezgin E
Article: NANO LETTERS. 2023;23(9):3701-3707

A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens.

Schlegel J; Porebski B; Andronico L; Hanke L; Edwards S; Brismar H; Murrell B; McInerney GM; Fernandez-Capetillo O; Sezgin E
Article: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2023;24(4):237

Voices of the new generation: normalizing career choices outside academia.

Sezgin E
Article: NATURE METABOLISM. 2023;5(3):495-515

PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing.

Cikes D; Elsayad K; Sezgin E; Koitai E; Torma F; Orthofer M; Yarwood R; Heinz LX; Sedlyarov V; Miranda ND; Taylor A; Grapentine S; Al-Murshedi F; Abot A; Weidinger A; Kutchukian C; Sanchez C; Cronin SJF; Novatchkova M; Kavirayani A; Schuetz T; Haubner B; Haas L; Hagelkruys A; Jackowski S; Kozlov AV; Jacquemond V; Knauf C; Superti-Furga G; Rullman E; Gustafsson T; McDermot J; Lowe M; Radak Z; Chamberlain JS; Bakovic M; Banka S; Penninger JM
Article: NATURE COMMUNICATIONS. 2022;13(1):7868

Modulating glycosphingolipid metabolism and autophagy improves outcomes in pre-clinical models of myeloma bone disease.

Leng H; Zhang H; Li L; Zhang S; Wang Y; Chavda SJ; Galas-Filipowicz D; Lou H; Ersek A; Morris EV; Sezgin E; Lee Y-H; Li Y; Lechuga-Vieco AV; Tian M; Mi J-Q; Yong K; Zhong Q; Edwards CM; Simon AK; Horwood NJ
Article: BIOPHYSICAL JOURNAL. 2022;121(20):3826-3836

Influence of the extracellular domain size on the dynamic behavior of membrane proteins.

Gurdap CO; Wedemann L; Sych T; Sezgin E
Article: OPEN BIOLOGY. 2022;12(9):220175

Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties.

Ragaller F; Andronico L; Sykora J; Kulig W; Rog T; Urem YB; Abhinav; Danylchuk DI; Hof M; Klymchenko A; Amaro M; Vattulainen I; Sezgin E
Article: NATURE COMMUNICATIONS. 2022;13(1):3460

T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles.

Céspedes PF; Jainarayanan A; Fernández-Messina L; Valvo S; Saliba DG; Kurz E; Kvalvaag A; Chen L; Ganskow C; Colin-York H; Fritzsche M; Peng Y; Dong T; Johnson E; Siller-Farfán JA; Dushek O; Sezgin E; Peacock B; Law A; Aubert D; Engledow S; Attar M; Hester S; Fischer R; Sánchez-Madrid F; Dustin ML
Article: BIOPHYSICAL REPORTS. 2022;2(2):None-100055

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5.

Galiani S; Reglinski K; Carravilla P; Barbotin A; Urbančič I; Ott J; Sehr J; Sezgin E; Schneider F; Waithe D; Hublitz P; Schliebs W; Erdmann R; Eggeling C
Journal article: BIOPHYSICAL REPORTS. 2022;2(2):None-100057

Erratum: Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.

Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Article: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2022;1864(4):183857

Giant plasma membrane vesicles to study plasma membrane structure and dynamics.

Sezgin E
Journal article: JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA. 2022;151(4):a154

Exploration of ultrasound-mediated microbubble-cell membrane interactions using novel protein-loaded microbubbles and their role in immunomodulation

Brans VA; Gray M; Sezgin E; Stride EP
Article: NATURE COMMUNICATIONS. 2022;13(1):155

A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo.

Hanke L; Das H; Sheward DJ; Perez Vidakovics L; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith NL; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen GK; Coquet JM; Hällberg BM; Murrell B; McInerney GM
Article: BIOPHYSICAL REPORTS. 2021;1(2):None-100023

Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes.

Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Article: SCIENCE ADVANCES. 2021;7(49):eabj9247

FOXN1 forms higher-order nuclear condensates displaced by mutations causing immunodeficiency.

Rota IA; Handel AE; Maio S; Klein F; Dhalla F; Deadman ME; Cheuk S; Newman JA; Michaels YS; Zuklys S; Prevot N; Hublitz P; Charles PD; Gkazi AS; Adamopoulou E; Qasim W; Davies EG; Hanson I; Pagnamenta AT; Camps C; Dreau HM; White A; James K; Fischer R; Gileadi O; Taylor JC; Fulga T; Lagerholm BC; Anderson G; Sezgin E; Holländer GA
Article: CELL REPORTS. 2021;37(5):109911

Regulatory T cell differentiation is controlled by αKG-induced alterations in mitochondrial metabolism and lipid homeostasis.

Matias MI; Yong CS; Foroushani A; Goldsmith C; Mongellaz C; Sezgin E; Levental KR; Talebi A; Perrault J; Rivière A; Dehairs J; Delos O; Bertand-Michel J; Portais J-C; Wong M; Marie JC; Kelekar A; Kinet S; Zimmermann VS; Levental I; Yvan-Charvet L; Swinnen JV; Muljo SA; Hernandez-Vargas H; Tardito S; Taylor N; Dardalhon V
Article: FEBS LETTERS. 2021;595(16):2127-2146

Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells.

Urbančič I; Schiffelers L; Jenkins E; Gong W; Santos AM; Schneider F; O'Brien-Ball C; Vuong MT; Ashman N; Sezgin E; Eggeling C
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):681

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function.

Oftedal BE; Maio S; Handel AE; White MPJ; Howie D; Davis S; Prevot N; Rota IA; Deadman ME; Kessler BM; Fischer R; Trede NS; Sezgin E; Maizels RM; Holländer GA
Article: ISCIENCE. 2021;24(1):101891

Influence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteins.

Schneider F; Sych T; Eggeling C; Sezgin E
Article: BIOMOLECULES. 2021;11(1):100

Nradd Acts as a Negative Feedback Regulator of Wnt/β-Catenin Signaling and Promotes Apoptosis.

Ozalp O; Cark O; Azbazdar Y; Haykir B; Cucun G; Kucukaylak I; Alkan-Yesilyurt G; Sezgin E; Ozhan G
Article: BIOCHEMISTRY. 2020;59(45):4421-4428

Lipoprotein Particles Interact with Membranes and Transfer Their Cargo without Receptors.

Plochberger B; Sych T; Weber F; Novacek J; Axmann M; Stangl H; Sezgin E
Article: ANALYTICAL CHEMISTRY. 2020;92(21):14798-14805

Redesigning Solvatochromic Probe Laurdan for Imaging Lipid Order Selectively in Cell Plasma Membranes.

Danylchuk DI; Sezgin E; Chabert P; Klymchenko AS
Journal article: CHEMICAL SCIENCE. 2020;11(33):8955-8960

Super-resolution RESOLFT microscopy of lipid bilayers using a fluorophore-switch dyad.

Frawley AT; Wycisk V; Xiong Y; Galiani S; Sezgin E; Urbančič I; Vargas Jentzsch A; Leslie KG; Eggeling C; Anderson HL
Article: PLOS PATHOGENS. 2020;16(7):e1008656

Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation.

Sieben C; Sezgin E; Eggeling C; Manley S
Article: NATURE CHEMICAL BIOLOGY. 2020;16(6):644-652

Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape.

Lorent JH; Levental KR; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova M; Lyman E; Levental I
Journal article: NATURE CHEMICAL BIOLOGY. 2020;16(6):710

Author Correction: Plasma membranes are asymmetric in lipid unsaturation, packing and protein shape.

Lorent JH; Levental KR; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova M; Lyman E; Levental I
Article: BIOPHYSICAL JOURNAL. 2020;118(10):2448-2457

z-STED Imaging and Spectroscopy to Investigate Nanoscale Membrane Structure and Dynamics.

Barbotin A; Urbančič I; Galiani S; Eggeling C; Booth M; Sezgin E
Article: JOURNAL OF PHYSICS D-APPLIED PHYSICS. 2020;53(16):164003

High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy.

Schneider F; Hernandez-Varas P; Christoffer Lagerholm B; Shrestha D; Sezgin E; Julia Roberti M; Ossato G; Hecht F; Eggeling C; Urbančič I
Article: JOURNAL OF PHYSICAL CHEMISTRY B. 2020;124(8):1487-1494

Impact of Nanoscale Hindrances on the Relationship between Lipid Packing and Diffusion in Model Membranes.

Beckers D; Urbancic D; Sezgin E
Article: MEMBRANES. 2020;10(2):E30-30

Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure.

Sezgin E; Carugo D; Levental I; Stride E; Eggeling C
Article: NATURE COMMUNICATIONS. 2020;11(1):756

Regulation of lipid saturation without sensing membrane fluidity.

Ballweg S; Sezgin E; Doktorova M; Covino R; Reinhard J; Wunnicke D; Hänelt I; Levental I; Hummer G; Ernst R
Journal article: BIOPHYSICAL JOURNAL. 2020;118(3):389a

Simulations of an Asymmetric Mammalian Lipidome

Doktorova M; Levental KR; Sezgin E; Levental I; Lyman ER
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:608484

Single-Molecule, Super-Resolution, and Functional Analysis of G Protein-Coupled Receptor Behavior Within the T Cell Immunological Synapse.

Felce JH; Parolini L; Sezgin E; Céspedes PF; Korobchevskaya K; Jones M; Peng Y; Dong T; Fritzsche M; Aarts D; Frater J; Dustin ML
Article: FRONTIERS IN IMMUNOLOGY. 2020;11:590121

Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition.

Lühr JJ; Alex N; Amon L; Kräter M; Kubánková M; Sezgin E; Lehmann CHK; Heger L; Heidkamp GF; Smith A-S; Zaburdaev V; Böckmann RA; Levental I; Dustin ML; Eggeling C; Guck J; Dudziak D
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2020;8:574363

Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae.

Reglinski K; Steinfort-Effelsberg L; Sezgin E; Klose C; Platta HW; Girzalsky W; Eggeling C; Erdmann R
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2019;294(34):12599-12609

Nanoscale dynamics of cholesterol in the cell membrane.

Pinkwart K; Schneider F; Lukoseviciute M; Sauka-Spengler T; Lyman E; Eggeling C; Sezgin E
Article: NANO LETTERS. 2019;19(4):2562-2567

Receptor-Independent Transfer of Low Density Lipoprotein Cargo to Biomembranes.

Axmann M; Sezgin E; Karner A; Novacek J; Brodesser MD; Röhrl C; Preiner J; Stangl H; Plochberger B
Article: NATURE PROTOCOLS. 2019;14(4):1054-1083

Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS.

Sezgin E; Schneider F; Galiani S; Urbančič I; Waithe D; Lagerholm BC; Eggeling C
Journal article: BIOPHYSICAL JOURNAL. 2019;116(3):327a-328a

Measuring Hindered Diffusion Dynamics in Live Cell Plasma Membranes with Confocal and Super-Resolution Imaging

Schneider F; Sezgin E; Waithe D; Fritzsche M; Eggeling C
Article: COMMUNICATIONS BIOLOGY. 2019;2:337

Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density.

Steinkühler J; Sezgin E; Urbančič I; Eggeling C; Dimova R
Article: FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY. 2019;7:281

More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains.

Azbazdar Y; Ozalp O; Sezgin E; Veerapathiran S; Duncan AL; Sansom MSP; Eggeling C; Wohland T; Karaca E; Ozhan G
Article: SCIENCE SIGNALING. 2018;11(561):eaat0756

CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity.

Felce JH; Sezgin E; Wane M; Brouwer H; Dustin ML; Eggeling C; Davis SJ
Article: BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES. 2018;1860(11):2436-2445

How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative.

Mobarak E; Javanainen M; Kulig W; Honigmann A; Sezgin E; Aho N; Eggeling C; Rog T; Vattulainen I
Article: JOURNAL OF CELL SCIENCE. 2018;132(4):jcs219709

Reconstitution of immune cell interactions in free-standing membranes.

Jenkins E; Santos AM; O'Brien-Ball C; Felce JH; Wilcock MJ; Hatherley D; Dustin ML; Davis SJ; Eggeling C; Sezgin E
Article: ACS NANO. 2018;12(8):8540-8546

Statistical Analysis of Scanning Fluorescence Correlation Spectroscopy Data Differentiates Free from Hindered Diffusion.

Schneider F; Waithe D; Lagerholm BC; Shrestha D; Sezgin E; Eggeling C; Fritzsche M
Journal article: ATHEROSCLEROSIS. 2018;275:e23

INTERACTION OF LIPOPROTEIN PARTICLES WITH LIPID BILAYER-MEMBRANES

Plochberger B; Roehrl C; Preiner J; Karner A; Axmann M; Novacek J; Sezgin E; Eggeling C; Hinterndorfer P; Schuetz GJ; Stangl H
Article: NANO LETTERS. 2018;18(7):4233-4240

Nanoscale Spatiotemporal Diffusion Modes Measured by Simultaneous Confocal and Stimulated Emission Depletion Nanoscopy Imaging.

Schneider F; Waithe D; Galiani S; Bernardino de la Serna J; Sezgin E; Eggeling C
Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2018;48(7):1120-1136

Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling.

Hertzog J; Dias Junior AG; Rigby RE; Donald CL; Mayer A; Sezgin E; Song C; Jin B; Hublitz P; Eggeling C; Kohl A; Rehwinkel J
Article: JOURNAL OF PHYSICS D-APPLIED PHYSICS. 2018;51(23):235401

Complementary studies of lipid membrane dynamics using iSCAT and super-resolved fluorescence correlation spectroscopy.

Reina F; Galiani S; Shrestha D; Sezgin E; de Wit G; Cole D; Christoffer Lagerholm B; Kukura P; Eggeling C
Journal article: CHEMICAL SCIENCE. 2018;9(15):3892

Correction: Spironaphthoxazine switchable dyes for biological imaging.

Xiong Y; Jentzsch AV; Osterrieth JWM; Sezgin E; Sazanovich IV; Reglinski K; Galiani S; Parker AW; Eggeling C; Anderson HL
Article: CHEMICAL SCIENCE. 2018;9(11):3029-3040

Spironaphthoxazine switchable dyes for biological imaging.

Xiong Y; Vargas Jentzsch A; Osterrieth JWM; Sezgin E; Sazanovich IV; Reglinski K; Galiani S; Parker AW; Eggeling C; Anderson HL
Article: SCIENTIFIC REPORTS. 2017;7(1):15886

HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study.

Plochberger B; Röhrl C; Preiner J; Rankl C; Brameshuber M; Madl J; Bittman R; Ros R; Sezgin E; Eggeling C; Hinterdorfer P; Stangl H; Schütz GJ
Article: BIOPHYSICAL JOURNAL. 2017;113(6):1321-1330

Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy.

Sezgin E; Schneider F; Zilles V; Urbančič I; Garcia E; Waithe D; Klymchenko AS; Eggeling C
Article: FEBS JOURNAL. 2017;284(15):2513-2526

Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments.

Sezgin E; Azbazdar Y; Ng XW; Teh C; Simons K; Weidinger G; Wohland T; Eggeling C; Ozhan G
Article: NATURE COMMUNICATIONS. 2017;8:15940

A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome.

Diepold A; Sezgin E; Huseyin M; Mortimer T; Eggeling C; Armitage JP
Article: MOLECULAR BIOLOGY OF THE CELL. 2017;28(11):1507-1518

Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS.

Schneider F; Waithe D; Clausen MP; Galiani S; Koller T; Ozhan G; Eggeling C; Sezgin E
Article: BMC BIOINFORMATICS. 2017;18(1):254

Spectral imaging toolbox: segmentation, hyperstack reconstruction, and batch processing of spectral images for the determination of cell and model membrane lipid order.

Aron M; Browning R; Carugo D; Sezgin E; Bernardino de la Serna J; Eggeling C; Stride E
Article: JOURNAL OF PHYSICS D-APPLIED PHYSICS. 2017;50(13):134004

Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane.

Amaro M; Reina F; Hof M; Eggeling C; Sezgin E
Article: ACS OMEGA. 2017;2(3):994-1002

Electroformation of Giant Unilamellar Vesicles on Stainless Steel Electrodes.

Pereno V; Carugo D; Bau L; Sezgin E; Bernardino de la Serna J; Eggeling C; Stride E
Article: NATURE COMMUNICATIONS. 2017;8:14347

Self-organizing actin patterns shape membrane architecture but not cell mechanics.

Fritzsche M; Li D; Colin-York H; Chang VT; Moeendarbary E; Felce JH; Sezgin E; Charras G; Betzig E; Eggeling C
Journal article: MATTERS. 2017

Rituximab capping triggers intracellular reorganization of B cells

Koller T; Blok S; Santos AM; Oszmiana A; Davis D; Sezgin E; Eggeling C
Article: FRONTIERS IN PHYSIOLOGY. 2017;8:252

Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin.

Rissanen S; Grzybek M; Orłowski A; Róg T; Cramariuc O; Levental I; Eggeling C; Sezgin E; Vattulainen I
Article: BIOMATERIALS. 2017;113:105-117

Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles.

Carugo D; Aron M; Sezgin E; Bernardino de la Serna J; Kuimova MK; Eggeling C; Stride E
Article: ORGANIC LETTERS. 2016;18(15):3666-3669

Photoswitchable Spiropyran Dyads for Biological Imaging.

Xiong Y; Rivera-Fuentes P; Sezgin E; Vargas Jentzsch A; Eggeling C; Anderson HL
Article: BIOPHYSICAL JOURNAL. 2016;110(11):2441-2450

Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy.

Steshenko O; Andrade DM; Honigmann A; Mueller V; Schneider F; Sezgin E; Hell SW; Simons M; Eggeling C
Article: BIOINFORMATICS. 2016;32(6):958-960

FoCuS-point: software for STED fluorescence correlation and time-gated single photon counting.

Waithe D; Clausen MP; Sezgin E; Eggeling C
Article: JOURNAL OF LIPID RESEARCH. 2016;57(2):299-309

A comparative study on fluorescent cholesterol analogs as versatile cellular reporters.

Sezgin E; Can FB; Schneider F; Clausen MP; Galiani S; Stanly TA; Waithe D; Colaco A; Honigmann A; Wüstner D; Platt F; Eggeling C
Article: METHODS. 2015;88:67-75

A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics.

Clausen MP; Sezgin E; Bernardino de la Serna J; Waithe D; Lagerholm BC; Eggeling C
Article: NANO LETTERS. 2015;15(9):5912-5918

STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics.

Vicidomini G; Ta H; Honigmann A; Mueller V; Clausen MP; Waithe D; Galiani S; Sezgin E; Diaspro A; Hell SW; Eggeling C
Journal article: CELL. 2015;161(6):1472

Membrane Nanoclusters-Tails of the Unexpected (vol 161, pg 433, 2015)

Sezgin E; Davis SJ; Eggeling C
Article: CHEMPHYSCHEM. 2015;16(7):1387-1394

Spectral imaging to measure heterogeneity in membrane lipid packing.

Sezgin E; Waithe D; Bernardino de la Serna J; Eggeling C
Journal article: CHEMPHYSCHEM. 2015;16(7):1560

Back Cover: Spectral Imaging to Measure Heterogeneity in Membrane Lipid Packing (ChemPhysChem 7/2015)

Sezgin E; Waithe D; de la Serna JB; Eggeling C
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2015;1853(4):802-809

Nanoclusters of the resting T cell antigen receptor (TCR) localize to non-raft domains.

Beck-García K; Beck-García E; Bohler S; Zorzin C; Sezgin E; Levental I; Alarcón B; Schamel WWA
Article: PLOS ONE. 2015;10(4):e0123930

Adaptive lipid packing and bioactivity in membrane domains.

Sezgin E; Gutmann T; Buhl T; Dirkx R; Grzybek M; Coskun Ü; Solimena M; Simons K; Levental I; Schwille P
Article: NATURE COMMUNICATIONS. 2014;5:5412

Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells.

Honigmann A; Mueller V; Ta H; Schoenle A; Sezgin E; Hell SW; Eggeling C
Article: LANGMUIR. 2014;30(27):8160-8166

Measuring lipid packing of model and cellular membranes with environment sensitive probes.

Sezgin E; Sadowski T; Simons K
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(50):35660-35670

Bile acids modulate signaling by functional perturbation of plasma membrane domains.

Zhou Y; Maxwell KN; Sezgin E; Lu M; Liang H; Hancock JF; Dial EJ; Lichtenberger LM; Levental I
Article: DEVELOPMENTAL CELL. 2013;26(4):331-345

Lypd6 enhances Wnt/β-catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains.

Özhan G; Sezgin E; Wehner D; Pfister AS; Kühl SJ; Kagermeier-Schenk B; Kühl M; Schwille P; Weidinger G
Article: CHEMBIOCHEM. 2013;14(6):695-698

Photoconversion of bodipy-labeled lipid analogues.

Sezgin E; Chwastek G; Aydogan G; Levental I; Simons K; Schwille P
Journal article: CHEMBIOCHEM. 2013;14(6):657

Cover Picture: Photoconversion of Bodipy‐Labeled Lipid Analogues (ChemBioChem 6/2013)

Sezgin E; Chwastek G; Aydogan G; Levental I; Simons K; Schwille P
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012;109(35):14236-14240

Functional convergence of hopanoids and sterols in membrane ordering.

Sáenz JP; Sezgin E; Schwille P; Simons K
Article: MOLECULAR MEMBRANE BIOLOGY. 2012;29(5):144-154

Model membrane platforms to study protein-membrane interactions.

Sezgin E; Schwille P
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2012;1818(7):1777-1784

Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes.

Sezgin E; Levental I; Grzybek M; Schwarzmann G; Mueller V; Honigmann A; Belov VN; Eggeling C; Coskun U; Simons K; Schwille P
Article: NATURE PROTOCOLS. 2012;7(6):1042-1051

Elucidating membrane structure and protein behavior using giant plasma membrane vesicles.

Sezgin E; Kaiser H-J; Baumgart T; Schwille P; Simons K; Levental I
Article: ACS NANO. 2012;6(3):2150-2156

Penetration of amphiphilic quantum dots through model and cellular plasma membranes.

Dubavik A; Sezgin E; Lesnyak V; Gaponik N; Schwille P; Eychmüller A
Article: COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY. 2011;3(11):a009803

Fluorescence techniques to study lipid dynamics.

Sezgin E; Schwille P
Article: COLLOIDS AND SURFACES B-BIOINTERFACES. 2009;71(2):315-318

Interaction of gold nanoparticles with mitochondria.

Karataş OF; Sezgin E; Aydin O; Culha M
Journal article:

Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation

Matias MI; Yong C; Foroushani A; Sezgin E; Levental K; Talebi A; Mongellaz C; Perrault J; Rivière A; Dehair J; Wong M; Kinet S; Zimmermann V; Levental I; Yvan-Charvet L; Swinnen J; Muljo S; Tardito S; Dardalhon V; Taylor N
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Preprint: BIORXIV. 2024

High-throughput analysis of membrane fluidity unveils a hidden dimension in immune cell states

Andronico LA; Jiang Y; Carannante V; Iskrak S; Sandoz PA; Mikes J; Klymchenko A; Buggert M; Österborg A; Önfelt B; Brodin P; Sezgin E
Preprint: BIORXIV. 2024;BIORXIV

A cholesterol switch controls phospholipid scrambling by G protein-coupled receptors.

Menon I; Sych T; Son Y; Morizumi T; Lee J; Ernst OP; Khelashvili G; Sezgin E; Levitz J; Menon AK
Preprint: BIORXIV. 2023

Discovery of a novel inhibitor of macropinocytosis with antiviral activity

Porebski B; Christ W; Corman A; Haraldsson M; Barz M; Lidemalm L; Häggblad M; Ilmain J; Wright SC; Murga M; Shlegel J; Sezgin E; Bhabha G; Lauschke VM; Lafarga M; Klingström J; Huhn D; Fernandez-Capetillo O
Preprint: BIORXIV. 2023

Quantifying fluorescence lifetime responsiveness of environment sensitive probes for membrane fluidity measurements

Ragaller F; Sjule E; Urem YB; Schlegel J; El R; Urbancic D; Urbancic I; Blom H; Sezgin E
Preprint: BIORXIV. 2023

Quantification of membrane fluidity in bacteria using TIR-FCS

Barbotin A; Billaudeau C; Sezgin E; Carballido-López R
Preprint: BIORXIV. 2023

Estrogen receptor activation remodelsTEAD1gene expression to alleviate nonalcoholic fatty liver disease

Sommerauer C; Gallardo-Dodd C; Savva C; Hases L; Birgersson M; Indukuri R; Shen J; Carravilla P; Geng K; Nørskov Søndergaard J; Ferrer-Aumatell C; Mercier G; Sezgin E; Korach-André M; Petersson C; Hagström H; Lauschke V; Archer A; Williams C; Kutter C
Preprint: BIORXIV. 2023

Apoptosis-mediated ADAM10 activation removes a mucin barrier promoting T cell efferocytosis

Drexhage LZ; Zhang S; DuPont M; Ragaller F; Sjule E; Caballero JC; Deimel L; Robertson H; Russell RA; Dushek O; Sezgin E; Karaji N; Sattentau QJ
Preprint: BIORXIV. 2023

Cell Membranes Sustain Phospholipid Imbalance Via Cholesterol Asymmetry

Doktorova M; Symons J; Zhang X; Wang H-Y; Schlegel J; Lorent J; Heberle F; Sezgin E; Lyman E; Levental K; Levental I
Preprint: RES SQ. 2023;RES SQ

Naltrexone blocks alcohol-induced effects on kappa-opioid receptors in the plasma membrane.

Terenius L; Oasa S; Sezgin E; Ma Y; Horne D; Radmiković M; Jovanović-Talisman T; Martin-Fardon R; Vukojevic V
Editorial comment: BIOPHYSICAL JOURNAL. 2023;122(11):E1-E4

Membranes in focus.

Sezgin E; Levental I
Preprint: BIORXIV. 2023

Engineered display of ganglioside-sugars on protein elicits a clonally and structurally constrained B cell response

Deimel LP; Xue X; Khan A; Moynie L; Buchanan CJ; Sun G; McBride R; Schuster H; Gauthier C; Saliba R; Leonavicus K; Minall L; Bort G; Russell RA; Sezgin E; Paulson JC; Anthony DC; Baldwin AJ; Naismith J; Schiffner T; Davis BG; Sattentau QJ
Other: NATURE CHEMICAL BIOLOGY. 2023;19(6):669-670

Do lipids tune B cell signaling?

Urbančič I; Eggeling C; Sezgin E
Corrigendum: NATURE METABOLISM. 2023;5(4):711

Author Correction: PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing.

Cikes D; Elsayad K; Sezgin E; Koitai E; Torma F; Orthofer M; Yarwood R; Heinz LX; Sedlyarov V; Miranda ND; Taylor A; Grapentine S; Al-Murshedi F; Abot A; Weidinger A; Kutchukian C; Sanchez C; Cronin SJF; Novatchkova M; Kavirayani A; Schuetz T; Haubner B; Haas L; Hagelkruys A; Jackowski S; Kozlov AV; Jacquemond V; Knauf C; Superti-Furga G; Rullman E; Gustafsson T; McDermot J; Lowe M; Radak Z; Chamberlain JS; Bakovic M; Banka S; Penninger JM
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):222A

HDL-membrane-interactions are highly influenced by the target membrane-lipid composition

Weber F; Stangl H; Synch T; Plochberger B; Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):224A

Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties

Ragaller F; Andronico L; Sykora J; Kulig W; Rog T; Urem YB; Abhinav A; Danylchuk DI; Hof M; Klymchenko AS; Amaro M; Vattulainen I; Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2023;122(3):362A

Measuring the fluidity of the membrane of Bacillus subtilis using TIR-FCS

Barbotin AGL; Lablaine A; Billaudeau C; Sezgin E; Carballido-Lopez R
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S83

High-throughput biophysical mapping for diagnostic

Gurdap C; Andronico L; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S158

A guideline for quantitative characterization and application of environment-sensitive probes

Urem YB; Sjule E; Ragaller F; Schlegel J; Andronico L; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S165

HDL-MEMBRANE-INTERACTIONS ARE HIGHLY INFLUENCED BY THE TARGET MEMBRANE-LIPID COMPOSITION

Weber F; Stangl H; Synch T; Plochberger B; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S64

Single particle profiler for measuring content and properties of nano-sized bioparticles

Sych T; Schlegel J; Barriga H; Ojansivu M; Hanke L; Weber F; Bostancioglu B; Ezzat K; Stangl H; Plochberger B; Laurencikiene J; El Andaloussi S; Furth D; Stevens M; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S123

Interpretation of STED-FCS diffusion law plots for nanoscopically heterogeneous membranes

Chmelova B; Koukalova A; Hof M; Sezgin E; Sachl R; Blom H
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S156

High-throughput and correlative membrane biophysical mapping of health and disease

Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S169

Cell biophysical properties unlock a new dimension in defining functional state of cells in health and diseases.

Andronico L; Jang Y; Iskrak S; Ragaller F; Sandoz P; Buggert M; Brodin P; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S164

Correlative spectral STED nanoscopy and STED-FCS elucidate the origin of anomalous diffusion in cellular membranes

Urbancic I; Schneider F; Galiani S; Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S151

Investigating contact formation and biophysical properties at the reconstituted immune synapse

Ragaller F; Andronico L; Achour A; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2023;52(SUPPL 1):S122

Revealing the mechanism of the lipid storage disorder Niemann-Pick C by combining multi-omics and biophysical imaging

Carravilla P; Ceplaite U; Sommerauer C; Veiga RG; Sezgin E; Kutter C
Preprint: BIORXIV. 2022

A Multiparametric and High-Throughput Platform for Host-Virus Binding Screens

Schlegel J; Porebski B; Andronico L; Hanke L; Edwards S; Brismar H; Murrell B; McInerney G; Fernandez-Capetillo O; Sezgin E
Preprint: BIORXIV. 2022

Single particle profiler for measuring content and properties of nano-sized bioparticles

Sych T; Schlegel J; Barriga HMG; Ojansivu M; Hanke L; Weber F; Bostancioglu RB; Ezzat K; Stangl H; Plochberger B; Laurencikiene J; Andaloussi SE; Fürth D; Stevens MM; Sezgin E
Preprint: BIORXIV. 2022

Dissecting the mechanisms of environment sensitivity of smart probes for quantitative assessment of membrane properties

Ragaller F; Andronico L; Sykora J; Kulig W; Rog T; Urem YB; Amaro M; Abhinav; Danylchuk DI; Klymchenko A; Hof M; Vattulainen I; Sezgin E
Review: ANNUAL REVIEW OF BIOPHYSICS. 2022;51:135-156

Lipid-Protein Interactions in Plasma Membrane Organization and Function.

Sych T; Levental KR; Sezgin E
Review: BIOCHEMICAL SOCIETY TRANSACTIONS. 2022;50(2):853-866

Understanding immune signaling using advanced imaging techniques.

Brameshuber M; Klotzsch E; Ponjavic A; Sezgin E
Editorial comment: JOURNAL OF CELL SCIENCE. 2022;135(7):jcs259977

Uniting diversity to create a more inclusive academic environment.

Delemotte L; Garcia SL; Rodríguez-Gijón A; Sezgin E; Vihervaara A
Preprint: BIORXIV. 2022

Critical role of PCYT2 in muscle health and aging

Cikes D; Elsayad K; Sezgin E; Koitai E; Ferenc T; Orthofer M; Yarwood R; Heinz L; Sedlyarov V; Miranda ND; Taylor A; Grapentine S; al-Murshedi F; Abott A; Weidinger A; Kutchukian C; Sanchez C; Cronin SJF; Novatchkova M; Kavirayani A; Schuetz T; Haubner B; Haas L; Hagelkruys A; Jackowski S; Kozlov A; Jacquemond V; Knauf C; Superti-Furga G; Rullman E; Gustafsson T; McDermot J; Lowe M; Radak Z; Chamberlain J; Bakovic M; Banka S; Penninger J
Conference publication: 2022;:5

From fluctuations to function: FFS to explore bio-molecular organisation

Schneider F; Cespedes PF; Sezgin E; Fritzsche M; Fraser SE
Conference publication: BIOPHYSICAL JOURNAL. 2022;121(3):302A

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5

Reglinski K; Galiani S; Carravilla P; Barbotin A; Urbancic I; Sezgin E; Schneider F; Waithe D; Schliebs W; Erdmann R; Eggeling C
Conference publication: BIOPHYSICAL JOURNAL. 2022;121(3):466A-467A

SFCS provides a window to bio-molecular organization

Schneider F; Cespedes PF; Fraser SE; Sezgin E; Fritzsche M
Conference publication: BIOPHYSICAL JOURNAL. 2022;121(3):34

Long-term superresolution imaging and quantification of live-cell plasma membrane biophysical properties with smart exchangeable dyes

Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Conference publication: FEBS OPEN BIO. 2022;12:205

Investigation of the functional role of neurotrophin receptor-associated death domain in neuronal development and microglia-glioblastoma interaction using the zebrafish model

Ozalp O; Cark O; Azbazdar Y; Haykir B; Cucun G; Sezgin E; Morisse G; Mazzolini J; Sieger D; Ozhan G
Book chapter: FLUORESCENCE SPECTROSCOPY AND MICROSCOPY IN BIOLOGY. 2022;p. 323-336

Diffusion Measurements at the Nanoscale with STED-FCS

Schneider F; Sezgin E
Preprint: BIORXIV. 2021

Influence of the extracellular domain size on the dynamic behavior of membrane proteins

Gurdap CO; Wedemann L; Sych T; Sezgin E
Preprint: RESEARCH SQUARE. 2021

Improving bone health via modulation of glycosphingolipid metabolism and autophagy

Leng H; Zhang H; Li L; Zhang S; Wang Y; Chavda S; Galas-Filipowicz D; Ersek A; Morris E; Sezgin E; Lee Y-H; Li Y; Mi J-Q; Yong K; Zhong Q; Edwards C; Simon AK; Horwood N
Preprint: BIORXIV. 2021

STED super-resolution imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes

Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk D; Klymchenko A; Sezgin E; Eggeling C
Preprint: BIORXIV. 2021

Synthetic antigen-presenting cells reveal the diversity and functional specialisation of extracellular vesicles composing the fourth signal of T cell immunological synapses

Céspedes PF; Jainarayanan A; Fernández-Messina L; Saliba DG; Valvo S; Kvalvaag A; Chen L; Kurz E; Ganskow C; Colin-York H; Fritzsche M; Peng Y; Dong T; Johnson E; Siller-Farfán JA; Dushek O; Sezgin E; Peacock B; Law A; Aubert D; Engledow S; Attar M; Hester S; Fischer R; Sánchez-Madrid F; Dustin ML
Preprint: BIORXIV. 2021

Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5

Galiani S; Reglinski K; Carravilla P; Barbotin A; Urbančič I; Ott J; Sehr J; Sezgin E; Schneider F; Waithe D; Hublitz P; Schliebs W; Erdmann R; Eggeling C
Review: MEMBRANES. 2021;11(5):323

How Does Liquid-Liquid Phase Separation in Model Membranes Reflect Cell Membrane Heterogeneity?

Sych T; Gurdap CO; Wedemann L; Sezgin E
Preprint: BIORXIV. 2021

A FOXN1 mutation competitively displaces wild-type FOXN1 from higher-order nuclear condensates to cause immunodeficiency

Rota IA; Handel AE; Klein F; Maio S; Dhalla F; Deadman ME; Cheuk S; Newman JA; Michaels YS; Zuklys S; Prevot N; Hublitz P; Charles PD; Gkazi AS; Adamopoulou E; Qasim W; Davies EG; Hanson C; Pagnamenta AT; Camps C; Dreau HM; White A; James K; Fischer R; Gileadi O; Taylor JC; Fulga T; Lagerholm BC; Anderson G; Sezgin E; Holländer GA
Preprint: BIORXIV. 2021

A bispecific monomeric nanobody induces spike trimer dimers and neutralizes SARS-CoV-2 in vivo

Hanke L; Das H; Sheward D; Vidakovics LP; Urgard E; Moliner-Morro A; Kim C; Karl V; Pankow A; Smith N; Porebski B; Fernandez-Capetillo O; Sezgin E; Pedersen G; Coquet J; Hällberg M; Murrell B; McInerney G
Preprint: BIORXIV. 2021

The glycosphingolipid inhibitor eliglustat inhibits autophagy in osteoclasts to increase bone mass and reduce myeloma bone disease

Leng H; Zhang H; Li L; Zhang S; Wang Y; Ersek A; Morris E; Sezgin E; Lee Y-H; Li Y; Mi J; Zhong Q; Edwards C; Simon AK; Horwood NJ
Review: FEBS JOURNAL. 2021;288(4):1070-1090

Model membrane systems to reconstitute immune cell signaling.

Céspedes PF; Beckers D; Dustin ML; Sezgin E
Editorial comment: FRONTIERS IN IMMUNOLOGY. 2021;12:740373

Editorial: The Role of Biomembranes and Biophysics in Immune Cell Signaling.

Shi Y; Sezgin E; Chen W
Conference publication: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51:235

Maturation of monocyte-derived DCs leads to increased cellular stiffness, higher membrane fluidity, and changed lipid composition

Luhr JJ; Alex N; Amon L; Kraeter M; Kubankova M; Sezgin E; Lehmann CHK; Heger L; Heidkamp GF; Smith AS; Zaburdaev V; Boeckmann RA; Levental I; Dustin ML; Eggeling C; Guck J; Dudziak D
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2021;50(SUPPL 1):100

Nanosized lipid particle profiling with fluorescence fluctuometry

Sych T; Plochberger B; Stangl H; Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2021;50(SUPPL 1):189

Membrane order change due to lipoprotein particles

Weber F; Axmann M; Sych T; Stangl H; Sezgin E; Plochberger B
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2021;50(SUPPL 1):81

Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells

Urbancic I; Schiffelers L; Jenkins E; Gong W; Santos AM; Schneider F; Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2021;50(SUPPL 1):80

Nanoscale biophysical properties of plasma membrane

Sezgin E
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2021;50(SUPPL 1):150

Exchangeable polarity-sensitive dyes for real-time quantification of membrane biophysical properties using STED super-resolution microscopy

Carravilla P; Dasgupta A; Zhurgenbayeva G; Danylchuk DI; Klymchenko AS; Sezgin E; Eggeling C
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2021;94(6)

WASP regulates early B cell receptor signaling and cytoskeletal rearrangements

Saeed M; Taal J; Sezgin E; Blom H; Westerberg L
Preprint: SSRN ELECTRONIC JOURNAL. 2021

Mitochondrial Metabolism Drives Triacylglycerol Synthesis to Control Regulatory T Cell Differentiation

Matias MI; Yong C; Foroushani A; Sezgin E; Levental K; Talebi A; Mongellaz C; Perrault J; Rivière A; Dehair J; Wong M; Kinet S; Zimmermann V; Levental I; Yvan-Charvet L; Swinnen J; Muljo S; Tardito S; Dardalhon V; Taylor N
Preprint: BIORXIV. 2020

Aggregation and immobilisation of membrane proteins interplay with local lipid order in the plasma membrane of T cells

Urbančič I; Schiffelers L; Jenkins E; Gong W; Santos AM; Schneider F; O’Brien-Ball C; Vuong MT; Ashman N; Sezgin E; Eggeling C
Preprint: BIORXIV. 2020

Lipoprotein particles interact with membranes and transfer their cargo without receptors

Plochberger B; Sych T; Weber F; Novacek J; Axmann M; Stangl H; Sezgin E
Preprint: BIORXIV. 2020

αKG inhibits Regulatory T cell differentiation by coupling lipidome remodelling to mitochondrial metabolism

Matias M; Yong C; Foroushani A; Sezgin E; Levental K; Talebi A; Mongellaz C; Dehair J; Wong M; Kinet S; Zimmermann V; Levental I; Yvan-Charvet L; Swinnen J; Muljo S; Tardito S; Dardalhon V; Taylor N
Preprint: BIORXIV. 2020

The chaperonin CCT8 controls proteostasis essential for T cell maturation, selection, and function

Oftedal BE; Maio S; Handel A; White MP; Howie D; Davis S; Prevot N; Rota IA; Deadman ME; Kessler BM; Fischer R; Trede NS; Sezgin E; Maizels RM; Holländer GA
Preprint: BIORXIV. 2020

Influence of nanobody binding on fluorescence emission, mobility and organization of GFP-tagged proteins

Schneider F; Eggeling C; Sezgin E
Corrigendum: NATURE CHEMICAL BIOLOGY. 2020;16(6):710

Author Correction: Hitchhiking into the cell.

Kell DB
Preprint: BIORXIV. 2020

Creating supported plasma membrane bilayers using acoustic pressure

Sezgin E; Carugo D; Levental I; Stride E; Eggeling C
Preprint: BIORXIV. 2020

Impact of nanoscale hindrances on the relationship between lipid packing and diffusion in model membranes

Beckers D; Urbancic D; Sezgin E
Preprint: BIORXIV. 2019

z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics

Barbotin A; Urbančič I; Galiani S; Eggeling C; Booth M; Sezgin E
Preprint: BIORXIV. 2019

High photon count rates improve the quality of super-resolution fluorescence fluctuation spectroscopy

Schneider F; Hernandez-Varas P; Lagerholm C; Shrestha D; Sezgin E; Roberti J; Ossato G; Hecht F; Eggeling C; Urbančič I
Preprint: BIORXIV. 2019

Regulation of lipid saturation without sensing membrane fluidity

Ballweg S; Sezgin E; Wunnicke D; Hänelt I; Ernst R
Preprint: BIORXIV. 2019

The mammalian plasma membrane is defined by transmembrane asymmetries in lipid unsaturation, leaflet packing, and protein shape

Lorent J; Levental K; Ganesan L; Rivera-Longsworth G; Sezgin E; Doktorova; Lyman E; Levental I
Preprint: BIORXIV. 2019

Mechanical properties of plasma membrane vesicles correlate with lipid order and viscosity and depend on cell density

Steinkühler J; Sezgin E; Urbančič I; Eggeling C; Dimova R
Preprint: BIORXIV. 2019

Nanoscale dynamics of cholesterol in the cell membrane

Pinkwart K; Schneider F; Lukoseviciute M; Sauka-Spengler T; Lyman E; Eggeling C; Sezgin E
Preprint: BIORXIV. 2018

Reconstitution of immune cell interactions in free-standing membranes

Jenkins E; Santos AM; Felce J; Hatherley D; Dustin M; Davis S; Eggeling C; Sezgin E
Preprint: BIORXIV. 2018

Nanoscale spatio-temporal diffusion modes measured by simultaneous confocal and STED imaging

Schneider F; Waithe D; Galiani S; de la Serna JB; Sezgin E; Eggeling C
Conference publication: 2018;10500:105000l

Interferometric scattering (iSCAT) microscopy: studies of biological membrane dynamics

Reina F; Galiani S; Shrestha D; Sezgin E; Lagerholm BC; Cole D; Kukura P; Eggeling C
Preprint: BIORXIV. 2018

Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation

Sieben C; Sezgin E; Eggeling C; Manley S
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):273A

Cell-Like Mechanical Response in Passive Plasma Membrane Vesicles

Steinkuehler J; Bhatial T; Urbancic I; Sezgin E; Westermann M; Lipowsky R; Dimova R
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):347A-348A

Direct Visualization of Lipoprotein Mediated Cholesterol Transport at the Phospholipid Bilayer Interface

Plochberger B; Axmann M; Sezgin E; Preiner J; Karner A; Roehrl C; Brodesser MD; Eggeling C; Schuetz GJ; Stangl H
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):99A

Advanced STED Microscopy of the Membrane Organization in Activating T-Cells

Urbancic I; Sezgin E; Schneider F; Reina F; Eggeling C
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):99A

STED-FCS Reveals Diffusional Heterogeneity of Lipids and GPI-Anchored Proteins in the Plasma Membrane and Actin Cytoskeleton Free Plasma Membrane Vesicles

Schneider F; Waithe D; Clausen MP; Galiani S; Koller T; Ozhan G; Eggeling C; Sezgin E
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):108A-109A

Triggering of the High-Affinity IgE Receptor in an AggregationIn-dependent Manner

Felce J; Sezgin E; Wane M; Dustin M; Eggeling C; Davis S
Conference publication: BIOPHYSICAL JOURNAL. 2018;114(3):16A

Spectral STED Imaging of Cell Membranes

Sezgin E; Schneider F; Zilles V; Urbancic I; Garcia E; Waithe D; Klymchenko A; Eggeling C
Preprint: BIORXIV. 2017

Complementary studies of lipid membrane dynamics using iSCAT and STED microscopy

Reina F; Galiani S; Shrestha D; Sezgin E; de Wit G; Cole D; Lagerholm BC; Kukura P; Eggeling C
Review: JOURNAL OF PHYSICS-CONDENSED MATTER. 2017;29(27):273001

Super-resolution optical microscopy for studying membrane structure and dynamics.

Sezgin E
Review: NATURE REVIEWS MOLECULAR CELL BIOLOGY. 2017;18(6):361-374

The mystery of membrane organization: composition, regulation and roles of lipid rafts.

Sezgin E; Levental I; Mayor S; Eggeling C
Preprint: BIORXIV. 2017

Polarity sensitive probes for super resolution STED microscopy

Sezgin E; Schneider F; Zilles V; Garcia E; Waithe D; Klymchenko AS; Eggeling C
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 2017;28

Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS.

Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017;46:S375

Triggering of the high-affinity IgE receptor in an aggregation-independent manner

Felce JH; Sezgin E; Wane M; Dustin ML; Eggeling C; Davis SJ
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017;46:S251

Ratiometric imaging with super-resolution STED microscopy to reveal nanoscale membrane heterogeneity

Sezgin E; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2017;46:S127

Diffusion of lipids and GPI-anchored proteins in the plasma membrane and actin free vesicles

Schneider F; Sezgin E; Waithe D; Eggeling C
Preprint: BIORXIV. 2016

Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane

Amaro M; Reina F; Hof M; Eggeling C; Sezgin E
Preprint: BIORXIV. 2016

Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS

Schneider F; Clausen M; Waithe D; Koller T; Ozhan G; Eggeling C; Sezgin E
Editorial comment: TRAFFIC. 2016;17(9):1054-1057

Use of BODIPY-Cholesterol (TF-Chol) for Visualizing Lysosomal Cholesterol Accumulation.

Hölttä-Vuori M; Sezgin E; Eggeling C; Ikonen E
Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):521A

Receptor-Mediated HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane

Plochberger B; Roehrl C; Preiner J; Weghuber J; Sezgin E; Hinterdorfer P; Stangl H; Schuetz GJ
Conference publication: BIOPHYSICAL JOURNAL. 2016;110(3):190A

Membrane Heterogeneity and its Role in Immune Signaling Elucidated by Spectral Imaging

Sezgin E; Eggeling C
Conference publication: FEBS JOURNAL. 2016;283:42

Investigating cell membrane dynamics by STED-FCS and spectral imaging

Sezgin E; Eggeling C
Editorial comment: CELL. 2015;161(3):433-434

Membrane nanoclusters-tails of the unexpected.

Sezgin E; Davis SJ; Eggeling C
Conference publication: EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS. 2015;44:S119

Role of membrane heterogeneity in immune signaling studied by model membranes and spectral imaging

Sezgin E; Eggeling C
Conference publication: BIOPHYSICAL JOURNAL. 2014;106(2):392A

HDL-Lipid Uptake is Regulated by Elastic Properties of the Plasma Membrane

Plochberger B; Schuetz GJ; Roehrl C; Preiner J; Sezgin E; Brameshuber M; Weghuber J; Wieser S; Rankl C; Ruprecht V; Madl J; Bittman R; Hinterdorfer P; Stangl H
Conference publication: BIOPHYSICAL JOURNAL. 2012;102(3):296A-297A

Partitioning, Diffusion, and Ligand Binding of Raft Lipid Analogs in Model and Cellular Plasma Membranes

Sezgin E; Levantal I; Schwarzmann G; Mueller V; Honigmann A; Belov V; Eggeling C; Coskun U; Simons K; Schwille P
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Genetic and immunological determinants of severe post-acute COVID-19-syndrome

Swedish Research Council

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