Forskningsbeskrivning
The Andersson lab aims to understand how multicellular organisms develop specialized organs systems with the correct cellular identity and architecture necessary for function, and how these systems are affected in disease and regeneration. As developmental biologists, we are interested in why and how genetic mutations lead to specific defects in embryogenesis. In order to study this in depth, we develop new technologies to analyze organs (eg DUCT, Hankeova et al, eLife 2021), or new methods to manipulate embryogenesis (eg NEPTUNE, Mangold et al Cell Reports Methods 2021). We are focused on Alagille syndrome, a congenital disorder affecting development of several organ systems including the liver and vasculature. We use mouse models, 3d cell culture, Crispr cell lines, single cell omics, and patient samples to address fundamental questions with relevance for human health.
Akademiska priser och utmärkelser
2017 The Daniel Alagille Award
This prize for one internationally competitive young scientist (under 40) in Europe is awarded by the European Association for the Study of the Liver (EASL), for research in the field of genetic cholestatic liver disorders (€ 25,000).
2017 EASL Mentoring Progamme recipient
This European mentorship program awards two mentees per year with a mentor, in international competition and provides funds for visits and networking. I was selected and matched with Mario Strazzabosco, Yale, USA.
2014 Sven och Ebba-Christina Hagbergs prize & grant
This prize for excellent young scientists, awarded every second year at Karolinska Institutet, is a personal prize (150,000SEK) and research grant (120,000SEK).