Elif Eroglu

About me
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About me

Our lab aims to discover principles of tissue regeneration through curiosity-driven science projects.

Research

Adult heart is one of the least regenerative organs in the human body. My group studies aquatic salamanders that have a fascinating regenerative capacity to ask how heart function can be restored.

Articles

Article: NATURE CELL BIOLOGY. 2022;24(5):659-671

Migratory and anti-fibrotic programmes define the regenerative potential of human cardiac progenitors.

Poch CM; Foo KS; De Angelis MT; Jennbacken K; Santamaria G; Bähr A; Wang Q-D; Reiter F; Hornaschewitz N; Zawada D; Bozoglu T; My I; Meier A; Dorn T; Hege S; Lehtinen ML; Tsoi YL; Hovdal D; Hyllner J; Schwarz S; Sudhop S; Jurisch V; Sini M; Fellows MD; Cummings M; Clarke J; Baptista R; Eroglu E; Wolf E; Klymiuk N; Lu K; Tomasi R; Dendorfer A; Gaspari M; Parrotta E; Cuda G; Krane M; Sinnecker D; Hoppmann P; Kupatt C; Fritsche-Danielson R; Moretti A; Chien KR; Laugwitz K-L
Article: NATURE CELL BIOLOGY. 2022;24(5):645-658

Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders.

Eroglu E; Yen CYT; Tsoi Y-L; Witman N; Elewa A; Joven Araus A; Wang H; Szattler T; Umeano CH; Sohlmér J; Goedel A; Simon A; Chien KR
Article: JCI INSIGHT. 2022;7(2):e152198

Sequencing of a Chinese tetralogy of Fallot cohort reveals clustering mutations in myogenic heart progenitors.

Tang CSM; Mononen M; Lam W-Y; Jin SC; Zhuang X; Garcia-Barcelo M-M; Lin Q; Yang Y; Sahara M; Eroglu E; Chien KR; Hong H; Tam PKH; Gruber PJ
Article: NATURE COMMUNICATIONS. 2021;12(1):5126

Amnion signals are essential for mesoderm formation in primates.

Yang R; Goedel A; Kang Y; Si C; Chu C; Zheng Y; Chen Z; Gruber PJ; Xiao Y; Zhou C; Witman N; Eroglu E; Leung C-Y; Chen Y; Fu J; Ji W; Lanner F; Niu Y; Chien KR
Article: DEVELOPMENT. 2019;146(23):dev183400

Dynamics of activating and repressive histone modifications in Drosophila neural stem cell lineages and brain tumors.

Abdusselamoglu MD; Landskron L; Bowman SK; Eroglu E; Burkard T; Kingston RE; Knoblich JA
Article: ELIFE. 2019;8:e46566

The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop.

Abdusselamoglu MD; Eroglu E; Burkard TR; Knoblich JA
Article: CELL. 2014;156(6):1259-1273

SWI/SNF complex prevents lineage reversion and induces temporal patterning in neural stem cells.

Eroglu E; Burkard TR; Jiang Y; Saini N; Homem CCF; Reichert H; Knoblich JA
Article: NATURE CELL BIOLOGY. 2011;13(9):1070-1075

Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells.

ten Berge D; Kurek D; Blauwkamp T; Koole W; Maas A; Eroglu E; Siu RK; Nusse R
Article: CELL STEM CELL. 2008;3(5):508-518

Wnt signaling mediates self-organization and axis formation in embryoid bodies.

ten Berge D; Koole W; Fuerer C; Fish M; Eroglu E; Nusse R

All other publications

Editorial comment: NATURE CELL BIOLOGY. 2021;23(5):440-442

PHF7 directs cardiac reprogramming.

Eroglu E; Schell JP; Chien KR
Editorial comment: CELL STEM CELL. 2018;22(6):787-789

Lnc'ed in to Cardiogenesis.

Sahara M; Eroglu E; Chien KR
Editorial comment: DEVELOPMENTAL CELL. 2017;42(1):7-8

Heart Regeneration 4.0: Matrix Medicine.

Eroglu E; Chien KR

Grants

KID Grant, Karolinska Institute

3 June 2024 - 31 December 2028
Wallenberg Academy Fellow 2023

Knut och Alice Wallenbergs Stiftelse

1 June 2024 - 30 June 2029
EMBO New Venture Fellow

European Molecular Biology Organization

14 June 2023 - 31 July 2023
Åke Wibergs Stiftelse

2 January 2023 - 31 December 2024
Starting Grant

Swedish Research Council

1 January 2023 - 31 December 2027
Ming Wai Lau Center Seed Grant

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Articles

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