David Tamborero

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: GENETICS IN MEDICINE. 2022;24(5):986-998

Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).

Horak P; Griffith M; Danos AM; Pitel BA; Madhavan S; Liu X; Chow C; Williams H; Carmody L; Barrow-Laing L; Rieke D; Kreutzfeldt S; Stenzinger A; Tamborero D; Benary M; Rajagopal PS; Ida CM; Lesmana H; Satgunaseelan L; Merker JD; Tolstorukov MY; Campregher PV; Warner JL; Rao S; Natesan M; Shen H; Venstrom J; Roy S; Tao K; Kanagal-Shamanna R; Xu X; Ritter DI; Pagel K; Krysiak K; Dubuc A; Akkari YM; Li XS; Lee J; King I; Raca G; Wagner AH; Li MM; Plon SE; Kulkarni S; Griffith OL; Chakravarty D; Sonkin D
Article: NATURE CANCER. 2022;3(2):251-261

The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Tamborero D; Dienstmann R; Rachid MH; Boekel J; Lopez-Fernandez A; Jonsson M; Razzak A; Braña I; De Petris L; Yachnin J; Baird RD; Loriot Y; Massard C; Martin-Romano P; Opdam F; Schlenk RF; Vernieri C; Masucci M; Villalobos X; Chavarria E; Cancer Core Europe consortium; Balmaña J; Apolone G; Caldas C; Bergh J; Ernberg I; Fröhling S; Garralda E; Karlsson C; Tabernero J; Voest E; Rodon J; Lehtiö J
Article: NATURE CANCER. 2021;2(11):1224-1242

Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune evasion mechanisms.

Lehtiö J; Arslan T; Siavelis I; Pan Y; Socciarelli F; Berkovska O; Umer HM; Mermelekas G; Pirmoradian M; Jönsson M; Brunnström H; Brustugun OT; Purohit KP; Cunningham R; Foroughi Asl H; Isaksson S; Arbajian E; Aine M; Karlsson A; Kotevska M; Gram Hansen C; Drageset Haakensen V; Helland Å; Tamborero D; Johansson HJ; Branca RM; Planck M; Staaf J; Orre LM
Article: HAEMATOLOGICA. 2021;106(8):2215-2223

Co-occurrence of cohesin complex and Ras signaling mutations during progression from myelodysplastic syndromes to secondary acute myeloid leukemia.

Martín-Izquierdo M; Abáigar M; Hernández-Sánchez JM; Tamborero D; López-Cadenas F; Ramos F; Lumbreras E; Madinaveitia-Ochoa A; Megido M; Labrador J; Sánchez-Real J; Olivier C; Dávila J; Aguilar C; Rodríguez JN; Martín-Nuñez G; Santos-Mínguez S; Miguel-García C; Benito R; Díez-Campelo M; Hernández-Rivas JM
Article: NATURE COMMUNICATIONS. 2020;11(1):4748

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples.

Bailey MH; Meyerson WU; Dursi LJ; Wang L-B; Dong G; Liang W-W; Weerasinghe A; Li S; Li Y; Kelso S; MC3 Working Group; PCAWG novel somatic mutation calling methods worki; Saksena G; Ellrott K; Wendl MC; Wheeler DA; Getz G; Simpson JT; Gerstein MB; Ding L; PCAWG Consortium
Article: NATURE COMMUNICATIONS. 2020;11(1):4330

Sex differences in oncogenic mutational processes.

Li CH; Prokopec SD; Sun RX; Yousif F; Schmitz N; PCAWG Tumour Subtypes and Clinical Translation; Boutros PC; PCAWG Consortium
Article: NATURE GENETICS. 2020;52(4):448-457

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer.

Wagner AH; Walsh B; Mayfield G; Tamborero D; Sonkin D; Krysiak K; Deu-Pons J; Duren RP; Gao J; McMurry J; Patterson S; Del Vecchio Fitz C; Pitel BA; Sezerman OU; Ellrott K; Warner JL; Rieke DT; Aittokallio T; Cerami E; Ritter DI; Schriml LM; Freimuth RR; Haendel M; Raca G; Madhavan S; Baudis M; Beckmann JS; Dienstmann R; Chakravarty D; Li XS; Mockus S; Elemento O; Schultz N; Lopez-Bigas N; Lawler M; Goecks J; Griffith M; Griffith OL; Margolin AA; Variant Interpretation for Cancer Consortium
Article: NATURE. 2020;578(7793):102-111

Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Rheinbay E; Nielsen MM; Abascal F; Wala JA; Shapira O; Tiao G; Hornshøj H; Hess JM; Juul RI; Lin Z; Feuerbach L; Sabarinathan R; Madsen T; Kim J; Mularoni L; Shuai S; Lanzós A; Herrmann C; Maruvka YE; Shen C; Amin SB; Bandopadhayay P; Bertl J; Boroevich KA; Busanovich J; Carlevaro-Fita J; Chakravarty D; Chan CWY; Craft D; Dhingra P; Diamanti K; Fonseca NA; Gonzalez-Perez A; Guo Q; Hamilton MP; Haradhvala NJ; Hong C; Isaev K; Johnson TA; Juul M; Kahles A; Kahraman A; Kim Y; Komorowski J; Kumar K; Kumar S; Lee D; Lehmann K-V; Li Y; Liu EM; Lochovsky L; Park K; Pich O; Roberts ND; Saksena G; Schumacher SE; Sidiropoulos N; Sieverling L; Sinnott-Armstrong N; Stewart C; Tamborero D; Tubio JMC; Umer HM; Uusküla-Reimand L; Wadelius C; Wadi L; Yao X; Zhang C-Z; Zhang J; Haber JE; Hobolth A; Imielinski M; Kellis M; Lawrence MS; von Mering C; Nakagawa H; Raphael BJ; Rubin MA; Sander C; Stein LD; Stuart JM; Tsunoda T; Wheeler DA; Johnson R; Reimand J; Gerstein M; Khurana E; Campbell PJ; López-Bigas N; PCAWG Drivers and Functional Interpretation Workin; PCAWG Structural Variation Working Group; Weischenfeldt J; Beroukhim R; Martincorena I; Pedersen JS; Getz G; PCAWG Consortium
Article: NATURE. 2020;578(7793):82-93

Pan-cancer analysis of whole genomes.

ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Con
Article: NATURE COMMUNICATIONS. 2020;11(1):729

Pathway and network analysis of more than 2500 whole cancer genomes.

Reyna MA; Haan D; Paczkowska M; Verbeke LPC; Vazquez M; Kahraman A; Pulido-Tamayo S; Barenboim J; Wadi L; Dhingra P; Shrestha R; Getz G; Lawrence MS; Pedersen JS; Rubin MA; Wheeler DA; Brunak S; Izarzugaza JMG; Khurana E; Marchal K; von Mering C; Sahinalp SC; Valencia A; PCAWG Drivers and Functional Interpretation Workin; Reimand J; Stuart JM; Raphael BJ; PCAWG Consortium
Article: COMMUNICATIONS BIOLOGY. 2020;3(1):56

Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis.

Carlevaro-Fita J; Lanzós A; Feuerbach L; Hong C; Mas-Ponte D; Pedersen JS; PCAWG Drivers and Functional Interpretation Group; Johnson R; PCAWG Consortium
Article: NATURE COMMUNICATIONS. 2020;11(1):735

Integrative pathway enrichment analysis of multivariate omics data.

Paczkowska M; Barenboim J; Sintupisut N; Fox NS; Zhu H; Abd-Rabbo D; Mee MW; Boutros PC; PCAWG Drivers and Functional Interpretation Workin; Reimand J; PCAWG Consortium
Article: NATURE COMMUNICATIONS. 2020;11(1):734

Combined burden and functional impact tests for cancer driver discovery using DriverPower.

Shuai S; PCAWG Drivers and Functional Interpretation Workin; Gallinger S; Stein LD; PCAWG Consortium
Article: NATURE COMMUNICATIONS. 2019;10(1):2674

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen.

Menden MP; Wang D; Mason MJ; Szalai B; Bulusu KC; Guan Y; Yu T; Kang J; Jeon M; Wolfinger R; Nguyen T; Zaslavskiy M; AstraZeneca-Sanger Drug Combination DREAM Consorti; Jang IS; Ghazoui Z; Ahsen ME; Vogel R; Neto EC; Norman T; Tang EKY; Garnett MJ; Veroli GYD; Fawell S; Stolovitzky G; Guinney J; Dry JR; Saez-Rodriguez J
Article: CLINICAL CANCER RESEARCH. 2019;25(5):1535-1545

NK Cell Infiltrates and HLA Class I Expression in Primary HER2+ Breast Cancer Predict and Uncouple Pathological Response and Disease-free Survival.

Muntasell A; Rojo F; Servitja S; Rubio-Perez C; Cabo M; Tamborero D; Costa-García M; Martínez-Garcia M; Menéndez S; Vazquez I; Lluch A; Gonzalez-Perez A; Rovira A; López-Botet M; Albanell J
Article: LEUKEMIA. 2019;33(2):518-558

CLL cells cumulate genetic aberrations prior to the first therapy even in outwardly inactive disease phase.

Hernández-Sánchez M; Kotaskova J; Rodríguez AE; Radova L; Tamborero D; Abáigar M; Plevova K; Benito R; Tom N; Quijada-Álamo M; Bikos V; Martín AÁ; Pal K; García de Coca A; Doubek M; López-Bigas N; Hernández-Rivas J-M; Pospisilova S
Article: CLINICAL CANCER RESEARCH. 2018;24(15):3717-3728

A Pan-cancer Landscape of Interactions between Solid Tumors and Infiltrating Immune Cell Populations.

Tamborero D; Rubio-Perez C; Muiños F; Sabarinathan R; Piulats JM; Muntasell A; Dienstmann R; Lopez-Bigas N; Gonzalez-Perez A
Article: CELL. 2018;173(2):371-385.e18

Comprehensive Characterization of Cancer Driver Genes and Mutations.

Bailey MH; Tokheim C; Porta-Pardo E; Sengupta S; Bertrand D; Weerasinghe A; Colaprico A; Wendl MC; Kim J; Reardon B; Ng PK-S; Jeong KJ; Cao S; Wang Z; Gao J; Gao Q; Wang F; Liu EM; Mularoni L; Rubio-Perez C; Nagarajan N; Cortés-Ciriano I; Zhou DC; Liang W-W; Hess JM; Yellapantula VD; Tamborero D; Gonzalez-Perez A; Suphavilai C; Ko JY; Khurana E; Park PJ; Van Allen EM; Liang H; MC3 Working Group; Cancer Genome Atlas Research Network; Lawrence MS; Godzik A; Lopez-Bigas N; Stuart J; Wheeler D; Getz G; Chen K; Lazar AJ; Mills GB; Karchin R; Ding L
Article: GENOME MEDICINE. 2018;10(1):25

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations.

Tamborero D; Rubio-Perez C; Deu-Pons J; Schroeder MP; Vivancos A; Rovira A; Tusquets I; Albanell J; Rodon J; Tabernero J; de Torres C; Dienstmann R; Gonzalez-Perez A; Lopez-Bigas N
Article: LEUKEMIA. 2018;32(3):675-684

Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.

Karube K; Enjuanes A; Dlouhy I; Jares P; Martin-Garcia D; Nadeu F; Ordóñez GR; Rovira J; Clot G; Royo C; Navarro A; Gonzalez-Farre B; Vaghefi A; Castellano G; Rubio-Perez C; Tamborero D; Briones J; Salar A; Sancho JM; Mercadal S; Gonzalez-Barca E; Escoda L; Miyoshi H; Ohshima K; Miyawaki K; Kato K; Akashi K; Mozos A; Colomo L; Alcoceba M; Valera A; Carrió A; Costa D; Lopez-Bigas N; Schmitz R; Staudt LM; Salaverria I; López-Guillermo A; Campo E
Article: ONCOTARGET. 2017;8(34):56338-56350

Identification of precision treatment strategies for relapsed/refractory multiple myeloma by functional drug sensitivity testing.

Majumder MM; Silvennoinen R; Anttila P; Tamborero D; Eldfors S; Yadav B; Karjalainen R; Kuusanmäki H; Lievonen J; Parsons A; Suvela M; Jantunen E; Porkka K; Heckman CA
Article: BLOOD. 2017;130(6):789-802

JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell-induced protection of AML.

Karjalainen R; Pemovska T; Popa M; Liu M; Javarappa KK; Majumder MM; Yadav B; Tamborero D; Tang J; Bychkov D; Kontro M; Parsons A; Suvela M; Mayoral Safont M; Porkka K; Aittokallio T; Kallioniemi O; McCormack E; Gjertsen BT; Wennerberg K; Knowles J; Heckman CA
Article: NATURE METHODS. 2017;14(8):782-788

Comparison of algorithms for the detection of cancer drivers at subgene resolution.

Porta-Pardo E; Kamburov A; Tamborero D; Pons T; Grases D; Valencia A; Lopez-Bigas N; Getz G; Godzik A
Article: LEUKEMIA. 2017;31(5):1048-1058

Monitoring therapy responses at the leukemic subclone level by ultra-deep amplicon resequencing in acute myeloid leukemia.

Ojamies PN; Kontro M; Edgren H; Ellonen P; Lagström S; Almusa H; Miettinen T; Eldfors S; Tamborero D; Wennerberg K; Heckman C; Porkka K; Wolf M; Kallioniemi O
Article: GENOME MEDICINE. 2016;8(1):98

Rational design of cancer gene panels with OncoPaD.

Rubio-Perez C; Deu-Pons J; Tamborero D; Lopez-Bigas N; Gonzalez-Perez A
Article: CELL. 2016;166(3):740-754

A Landscape of Pharmacogenomic Interactions in Cancer.

Iorio F; Knijnenburg TA; Vis DJ; Bignell GR; Menden MP; Schubert M; Aben N; Gonçalves E; Barthorpe S; Lightfoot H; Cokelaer T; Greninger P; van Dyk E; Chang H; de Silva H; Heyn H; Deng X; Egan RK; Liu Q; Mironenko T; Mitropoulos X; Richardson L; Wang J; Zhang T; Moran S; Sayols S; Soleimani M; Tamborero D; Lopez-Bigas N; Ross-Macdonald P; Esteller M; Gray NS; Haber DA; Stratton MR; Benes CH; Wessels LFA; Saez-Rodriguez J; McDermott U; Garnett MJ
Article: NATURE. 2015;526(7574):519-524

Non-coding recurrent mutations in chronic lymphocytic leukaemia.

Puente XS; Beà S; Valdés-Mas R; Villamor N; Gutiérrez-Abril J; Martín-Subero JI; Munar M; Rubio-Pérez C; Jares P; Aymerich M; Baumann T; Beekman R; Belver L; Carrio A; Castellano G; Clot G; Colado E; Colomer D; Costa D; Delgado J; Enjuanes A; Estivill X; Ferrando AA; Gelpí JL; González B; González S; González M; Gut M; Hernández-Rivas JM; López-Guerra M; Martín-García D; Navarro A; Nicolás P; Orozco M; Payer ÁR; Pinyol M; Pisano DG; Puente DA; Queirós AC; Quesada V; Romeo-Casabona CM; Royo C; Royo R; Rozman M; Russiñol N; Salaverría I; Stamatopoulos K; Stunnenberg HG; Tamborero D; Terol MJ; Valencia A; López-Bigas N; Torrents D; Gut I; López-Guillermo A; López-Otín C; Campo E
Article: CANCER CELL. 2015;27(3):382-396

In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals targeting opportunities.

Rubio-Perez C; Tamborero D; Schroeder MP; Antolín AA; Deu-Pons J; Perez-Llamas C; Mestres J; Gonzalez-Perez A; Lopez-Bigas N
Article: NATURE GENETICS. 2015;47(2):106-114

Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes.

Leiserson MDM; Vandin F; Wu H-T; Dobson JR; Eldridge JV; Thomas JL; Papoutsaki A; Kim Y; Niu B; McLellan M; Lawrence MS; Gonzalez-Perez A; Tamborero D; Cheng Y; Ryslik GA; Lopez-Bigas N; Getz G; Ding L; Raphael BJ
Article: CELL. 2014;158(4):929-944

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin.

Hoadley KA; Yau C; Wolf DM; Cherniack AD; Tamborero D; Ng S; Leiserson MDM; Niu B; McLellan MD; Uzunangelov V; Zhang J; Kandoth C; Akbani R; Shen H; Omberg L; Chu A; Margolin AA; Van't Veer LJ; Lopez-Bigas N; Laird PW; Raphael BJ; Ding L; Robertson AG; Byers LA; Mills GB; Weinstein JN; Van Waes C; Chen Z; Collisson EA; Cancer Genome Atlas Research Network; Benz CC; Perou CM; Stuart JM
Article: GENOME RESEARCH. 2014;24(2):212-226

Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia.

Ferreira PG; Jares P; Rico D; Gómez-López G; Martínez-Trillos A; Villamor N; Ecker S; González-Pérez A; Knowles DG; Monlong J; Johnson R; Quesada V; Djebali S; Papasaikas P; López-Guerra M; Colomer D; Royo C; Cazorla M; Pinyol M; Clot G; Aymerich M; Rozman M; Kulis M; Tamborero D; Gouin A; Blanc J; Gut M; Gut I; Puente XS; Pisano DG; Martin-Subero JI; López-Bigas N; López-Guillermo A; Valencia A; López-Otín C; Campo E; Guigó R
Article: NATURE METHODS. 2013;10(11):1081-1082

IntOGen-mutations identifies cancer drivers across tumor types.

Gonzalez-Perez A; Perez-Llamas C; Deu-Pons J; Tamborero D; Schroeder MP; Jene-Sanz A; Santos A; Lopez-Bigas N
Article: SCIENTIFIC REPORTS. 2013;3:2650

Comprehensive identification of mutational cancer driver genes across 12 tumor types.

Tamborero D; Gonzalez-Perez A; Perez-Llamas C; Deu-Pons J; Kandoth C; Reimand J; Lawrence MS; Getz G; Bader GD; Ding L; Lopez-Bigas N
Article: BIOINFORMATICS. 2013;29(18):2238-2244

OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes.

Tamborero D; Gonzalez-Perez A; Lopez-Bigas N
Article: PLOS ONE. 2013;8(2):e55489

Oncodrive-CIS: a method to reveal likely driver genes based on the impact of their copy number changes on expression.

Tamborero D; Lopez-Bigas N; Gonzalez-Perez A
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2011;108(12):1741-1746

Effect of repeated radiofrequency catheter ablation on left atrial function for the treatment of atrial fibrillation.

Montserrat S; Sitges M; Calvo N; Silva E; Tamborero D; Vidal B; Berruezo A; Bernado C; Mont L; Brugada J
Article: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. 2011;22(10):1129-1134

Electrocardiographic versus echocardiographic optimization of the interventricular pacing delay in patients undergoing cardiac resynchronization therapy.

Tamborero D; Vidal B; Tolosana JM; Sitges M; Berruezo A; Silva E; Castel M; Matas M; Arbelo E; Rios J; Villacastín J; Brugada J; Mont L
Article: PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY. 2011;34(8):984-990

Comparison of hemodynamic versus dyssynchrony assessment for interventricular delay optimization with echocardiography in cardiac resynchronization therapy.

Doltra A; Vidal B; Silva E; Mont L; Tamborero D; Castel MÁ; Tolosana JM; Berruezo A; Brugada J; Sitges M
Article: EUROPACE. 2011;13(4):486-491

Usefulness of transoesophageal echocardiography before circumferential pulmonary vein ablation in patients with atrial fibrillation: is it really mandatory?

Calvo N; Mont L; Vidal B; Nadal M; Montserrat S; Andreu D; Tamborero D; Pare C; Azqueta M; Berruezo A; Brugada J; Sitges M
Article: EUROPACE. 2010;12(8):1136-1140

Survival in New York Heart Association class IV heart failure patients treated with cardiac resynchronization therapy compared with patients on optimal pharmacological treatment.

Castel MA; Magnani S; Mont L; Roig E; Tamborero D; Méndez-Zurita F; Femenia JF; Tolosana JM; Pérez-Villa F; Brugada J
Article: EUROPACE. 2010;12(8):1084-1089

Low efficacy of atrial fibrillation ablation in severe obstructive sleep apnoea patients.

Matiello M; Nadal M; Tamborero D; Berruezo A; Montserrat J; Embid C; Rios J; Villacastín J; Brugada J; Mont L
Article: HEART RHYTHM. 2010;7(5):612-618

Circumferential pulmonary vein ablation: does use of a circular mapping catheter improve results? A prospective randomized study.

Tamborero D; Mont L; Berruezo A; Guasch E; Rios J; Nadal M; Matiello M; Andreu D; Sitges M; Brugada J
Article: EUROPEAN JOURNAL OF HEART FAILURE. 2010;12(5):492-498

Plasma tissue inhibitor of matrix metalloproteinase-1 (TIMP-1): an independent predictor of poor response to cardiac resynchronization therapy.

Tolosana JM; Mont L; Sitges M; Berruezo A; Delgado V; Vidal B; Tamborero D; Morales M; Batlle M; Roig E; Castel MA; Pérez-Villa F; Godoy M; Brugada J
Article: JOURNAL OF CARDIAC FAILURE. 2010;16(4):357-366

Effects of adipose tissue-derived stem cell therapy after myocardial infarction: impact of the route of administration.

Rigol M; Solanes N; Farré J; Roura S; Roqué M; Berruezo A; Bellera N; Novensà L; Tamborero D; Prat-Vidal C; Huzman MAA; Batlle M; Hoefsloot M; Sitges M; Ramírez J; Dantas AP; Merino A; Sanz G; Brugada J; Bayés-Genís A; Heras M
Article: EUROPACE. 2010;12(1):30-36

Efficacy of circumferential pulmonary vein ablation of atrial fibrillation in endurance athletes.

Calvo N; Mont L; Tamborero D; Berruezo A; Viola G; Guasch E; Nadal M; Andreu D; Vidal B; Sitges M; Brugada J
Article: EUROPACE. 2010;12(1):24-29

Left ventricular systolic dysfunction by itself does not influence outcome of atrial fibrillation ablation.

De Potter T; Berruezo A; Mont L; Matiello M; Tamborero D; Santibañez C; Benito B; Zamorano N; Brugada J
Article: EUROPACE. 2009;11(12):1675-1682

Midterm 'super-response' to cardiac resynchronization therapy by biventricular pacing with fusion: insights from electro-anatomical mapping.

Vatasescu R; Berruezo A; Mont L; Tamborero D; Sitges M; Silva E; Tolosana JM; Vidal B; Andreu D; Brugada J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2009;104(10):1407-1412

Optimization of the interventricular delay in cardiac resynchronization therapy using the QRS width.

Tamborero D; Mont L; Sitges M; Silva E; Berruezo A; Vidal B; Delgado V; Tolosana JM; Godoy M; Castel A; Brugada J
Article: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. 2009;20(10):1130-1136

Quantification of left ventricular asynchrony throughout the whole cardiac cycle with a computed algorithm: application for optimizing resynchronization therapy.

Silva E; Sitges M; Mont L; Delgado V; Tamborero D; Vidal B; Godoy M; Poyatos S; Pare C; Azqueta M; Brugada J
Article: EUROPEAN HEART JOURNAL. 2009;30(15):1880-1884

Preparation for pacemaker or implantable cardiac defibrillator implants in patients with high risk of thrombo-embolic events: oral anticoagulation or bridging with intravenous heparin? A prospective randomized trial.

Tolosana JM; Berne P; Mont L; Heras M; Berruezo A; Monteagudo J; Tamborero D; Benito B; Brugada J
Article: EUROPACE. 2009;11(3):338-342

Six-minute walking test predicts long-term cardiac death in patients who received cardiac resynchronization therapy.

Castel MA; Méndez F; Tamborero D; Mont L; Magnani S; Tolosana JM; Berruezo A; Godoy M; Sitges M; Vidal B; Roig E; Brugada J
Article: CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY. 2009;2(1):35-40

Left atrial posterior wall isolation does not improve the outcome of circumferential pulmonary vein ablation for atrial fibrillation: a prospective randomized study.

Tamborero D; Mont L; Berruezo A; Matiello M; Benito B; Sitges M; Vidal B; de Caralt TM; Perea RJ; Vatasescu R; Brugada J
Article: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. 2008;52(19):1567-1573

Gender differences in clinical manifestations of Brugada syndrome.

Benito B; Sarkozy A; Mont L; Henkens S; Berruezo A; Tamborero D; Arzamendi D; Berne P; Brugada R; Brugada P; Brugada J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2008;102(4):444-449

Comparison of benefits and mortality in cardiac resynchronization therapy in patients with atrial fibrillation versus patients in sinus rhythm (Results of the Spanish Atrial Fibrillation and Resynchronization [SPARE] Study).

Tolosana JM; Hernandez Madrid A; Brugada J; Sitges M; Garcia Bolao I; Fernandez Lozano I; Martinez Ferrer J; Quesada A; Macias A; Marin W; Escudier JM; Gomez AA; Gimenez Alcala M; Tamborero D; Berruezo A; Mont L; SPARE Investigators
Article: EUROPACE. 2008;10(8):955-960

Cooled-tip vs. 8 mm-tip catheter for circumferential pulmonary vein ablation: comparison of efficacy, safety, and lesion extension.

Matiello M; Mont L; Tamborero D; Berruezo A; Benito B; Gonzalez E; Brugada J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2008;101(9):1285-1290

Fate of left atrial function as determined by real-time three-dimensional echocardiography study after radiofrequency catheter ablation for the treatment of atrial fibrillation.

Delgado V; Vidal B; Sitges M; Tamborero D; Mont L; Berruezo A; Azqueta M; Paré C; Brugada J
Article: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. 2008;19(4):374-379

Left atrial contractility is preserved after successful circumferential pulmonary vein ablation in patients with atrial fibrillation.

Perea RJ; Tamborero D; Mont L; De Caralt TM; Ortiz JT; Berruezo A; Matiello M; Sitges M; Vidal B; Sanchez M; Brugada J
Article: EUROPACE. 2008;10(1):15-20

Physical activity, height, and left atrial size are independent risk factors for lone atrial fibrillation in middle-aged healthy individuals.

Mont L; Tamborero D; Elosua R; Molina I; Coll-Vinent B; Sitges M; Vidal B; Scalise A; Tejeira A; Berruezo A; Brugada J; GIRAFA (Grup Integrat de Recerca en Fibril-lació A
Article: EUROPACE. 2008;10(1):105-109

Characterization of focal right atrial appendage tachycardia.

Freixa X; Berruezo A; Mont L; Magnani S; Benito B; Tolosana JM; Perafan P; Tamborero D; Brugada J
Article: EUROPACE. 2008;10(1):9-14

Predictors of arrhythmia recurrence in patients with lone atrial fibrillation.

Arriagada G; Berruezo A; Mont L; Tamborero D; Molina I; Coll-Vinent B; Vidal B; Sitges M; Berne P; Brugada J; GIRAFA (Grup Integrat de Recerca en Fibril.lació A
Article: REVISTA ESPANOLA DE CARDIOLOGIA. 2007;60(12):1264-1271

[Influence of cardiopathy etiology on responses to cardiac resynchronization therapy].

Vidal B; Sitges M; Delgado V; Mont L; Díaz-Infante E; Azqueta M; Paré C; Tolosana JM; Berruezo A; Tamborero D; Roig E; Brugada J
Article: JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY. 2007;18(12):1252-1257

Electrocardiographic optimization of interventricular delay in cardiac resynchronization therapy: a simple method to optimize the device.

Vidal B; Tamborero D; Mont L; Sitges M; Delgado V; Berruezo A; Díaz-Infante E; Tolosana JM; Paré C; Brugada J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2007;100(6):1002-1006

Optimizing the programation of cardiac resynchronization therapy devices in patients with heart failure and left bundle branch block.

Vidal B; Sitges M; Marigliano A; Delgado V; Díaz-Infante E; Azqueta M; Tamborero D; Tolosana JM; Berruezo A; Pérez-Villa F; Paré C; Mont L; Brugada J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2007;100(1):84-89

Usefulness of ventricular dyssynchrony measured using M-mode echocardiography to predict response to resynchronization therapy.

Díaz-Infante E; Sitges M; Vidal B; Mont L; Delgado V; Marigliano A; Macias A; Tolosana JM; Tamborero D; Azqueta M; Roig E; Paré C; Brugada J
Article: JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY. 2007;19(1):19-27

Selective segmental ostial ablation and circumferential pulmonary veins ablation. Results of an individualized strategy to cure refractory atrial fibrillation.

Tamborero D; Mont L; Molina I; Matiello M; Berruezo A; Sitges M; Perea RJ; de Caralt TM; Vidal B; Zamorano N; Brugada J
Article: EUROPACE. 2007;9(5):294-298

Is there an anatomical substrate for idiopathic paroxysmal atrial fibrillation? A case-control echocardiographic study.

Sitges M; Teijeira VA; Scalise A; Vidal B; Tamborero D; Collvinent B; Rivera S; Molina I; Azqueta M; Paré C; Brugada J; Mont L
Article: EUROPEAN HEART JOURNAL. 2007;28(7):836-841

Pre-procedural predictors of atrial fibrillation recurrence after circumferential pulmonary vein ablation.

Berruezo A; Tamborero D; Mont L; Benito B; Tolosana JM; Sitges M; Vidal B; Arriagada G; Méndez F; Matiello M; Molina I; Brugada J
Article: PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY. 2006;29(9):940-945

Anodal capture in cardiac resynchronization therapy implications for device programming.

Tamborero D; Mont L; Alanis R; Berruezo A; Tolosana JM; Sitges M; Vidal B; Brugada J
Article: AMERICAN JOURNAL OF CARDIOLOGY. 2006;97(6):876-881

Relation of response to cardiac resynchronization therapy to left ventricular reverse remodeling.

Vidal B; Sitges M; Marigliano A; Díaz-Infante E; Azqueta M; Tamborero D; Macías A; Roig E; Brugada J; Paré C; Mont L
Article: JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY. 2005;14(1):21-25

Incidence of pulmonary vein stenosis in patients submitted to atrial fibrillation ablation: a comparison of the Selective Segmental Ostial Ablation vs the Circumferential Pulmonary Veins Ablation.

Tamborero D; Mont L; Nava S; de Caralt TM; Molina I; Scalise A; Perea RJ; Bartholomay E; Berruezo A; Matiello M; Brugada J
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Corrigendum: NATURE. 2023;614(7948):E40

Author Correction: Analyses of non-coding somatic drivers in 2,658 cancer whole genomes.

Rheinbay E; Nielsen MM; Abascal F; Wala JA; Shapira O; Tiao G; Hornshøj H; Hess JM; Juul RI; Lin Z; Feuerbach L; Sabarinathan R; Madsen T; Kim J; Mularoni L; Shuai S; Lanzós A; Herrmann C; Maruvka YE; Shen C; Amin SB; Bandopadhayay P; Bertl J; Boroevich KA; Busanovich J; Carlevaro-Fita J; Chakravarty D; Chan CWY; Craft D; Dhingra P; Diamanti K; Fonseca NA; Gonzalez-Perez A; Guo Q; Hamilton MP; Haradhvala NJ; Hong C; Isaev K; Johnson TA; Juul M; Kahles A; Kahraman A; Kim Y; Komorowski J; Kumar K; Kumar S; Lee D; Lehmann K-V; Li Y; Liu EM; Lochovsky L; Park K; Pich O; Roberts ND; Saksena G; Schumacher SE; Sidiropoulos N; Sieverling L; Sinnott-Armstrong N; Stewart C; Tamborero D; Tubio JMC; Umer HM; Uusküla-Reimand L; Wadelius C; Wadi L; Yao X; Zhang C-Z; Zhang J; Haber JE; Hobolth A; Imielinski M; Kellis M; Lawrence MS; von Mering C; Nakagawa H; Raphael BJ; Rubin MA; Sander C; Stein LD; Stuart JM; Tsunoda T; Wheeler DA; Johnson R; Reimand J; Gerstein M; Khurana E; Campbell PJ; López-Bigas N; PCAWG Drivers and Functional Interpretation Workin; PCAWG Structural Variation Working Group; Weischenfeldt J; Beroukhim R; Martincorena I; Pedersen JS; Getz G; PCAWG Consortium
Corrigendum: NATURE CANCER. 2022;3(5):649

Author Correction: The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Tamborero D; Dienstmann R; Rachid MH; Boekel J; Lopez-Fernandez A; Jonsson M; Razzak A; Braña I; De Petris L; Yachnin J; Baird RD; Loriot Y; Massard C; Martin-Romano P; Opdam F; Schlenk RF; Vernieri C; Masucci M; Villalobos X; Chavarria E; Cancer Core Europe consortium; Balmaña J; Apolone G; Caldas C; Bergh J; Ernberg I; Fröhling S; Garralda E; Karlsson C; Tabernero J; Voest E; Rodon J; Lehtiö J
Editorial comment: JCO PRECISION ONCOLOGY. 2021;5:974-980

Discordant Reporting of a Previously Undescribed Pathogenic Germline BRCA2 Variant in Blood and Tumor Tissue in a Patient With Pancreatic Adenocarcinoma.

Kordes M; Tamborero D; Lagerstedt-Robinson K; Yachnin J; Rosenquist R; Löhr J-M; Gustafsson Liljefors M
Editorial comment: ANNALS OF ONCOLOGY. 2021;32(7):837-838

Genomic testing for targeted oncology drugs: hopes against hype.

Dienstmann R; Tamborero D
Letter: NATURE MEDICINE. 2020;26(7):992-994

Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal.

Tamborero D; Dienstmann R; Rachid MH; Boekel J; Baird R; Braña I; De Petris L; Yachnin J; Massard C; Opdam FL; Schlenk R; Vernieri C; Garralda E; Masucci M; Villalobos X; Chavarria E; Cancer Core Europe consortium; Calvo F; Fröhling S; Eggermont A; Apolone G; Voest EE; Caldas C; Tabernero J; Ernberg I; Rodon J; Lehtiö J
Editorial comment: NATURE GENETICS. 2017;49(2):170-174

CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer.

Griffith M; Spies NC; Krysiak K; McMichael JF; Coffman AC; Danos AM; Ainscough BJ; Ramirez CA; Rieke DT; Kujan L; Barnell EK; Wagner AH; Skidmore ZL; Wollam A; Liu CJ; Jones MR; Bilski RL; Lesurf R; Feng Y-Y; Shah NM; Bonakdar M; Trani L; Matlock M; Ramu A; Campbell KM; Spies GC; Graubert AP; Gangavarapu K; Eldred JM; Larson DE; Walker JR; Good BM; Wu C; Su AI; Dienstmann R; Margolin AA; Tamborero D; Lopez-Bigas N; Jones SJM; Bose R; Spencer DH; Wartman LD; Wilson RK; Mardis ER; Griffith OL
Published conference paper: BIOINFORMATICS. 2014;30(17):i549-i555

OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action.

Schroeder MP; Rubio-Perez C; Tamborero D; Gonzalez-Perez A; Lopez-Bigas N
Published conference paper: BIOINFORMATICS. 2014;30(17):i617-i623

Fast randomization of large genomic datasets while preserving alteration counts.

Gobbi A; Iorio F; Dawson KJ; Wedge DC; Tamborero D; Alexandrov LB; Lopez-Bigas N; Garnett MJ; Jurman G; Saez-Rodriguez J
Letter: AMERICAN JOURNAL OF CARDIOLOGY. 2009;103(6):894

Electrocardiographic optimization of cardiac resynchronization devices: simple, but not so simple!

Mont L; Sitges M; Delgado V; Vidal B; Tamborero D; Brugada J

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