Om mig
Jag har över 35 års erfarenhet som kliniker i psykiatrivården och bedriver som forskare longitudinella fall-kontrollstudier inom schizofreni. 2009 blev jag professor i psykiatrisk epidemiologi vid Karolinska Institutet.
Läs mer om min forskning på den engelska profilsidan
Forskningsbeskrivning
Urval av originalartiklar
- De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Cicek AE, et al. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature. 2014;515(7526):209-15.
- Genovese G, Kähler AK, Handsaker RE, Lindberg J, Rose SA, Bakhoum SF, et al. Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence. New England Journal of Medicine. 2014;371(26):2477-87.
- Hultman CM, Geddes J, Sparén P, Takei N, Murray RM, Cnattingius S. PapersPrenatal and perinatal risk factors for schizophrenia, affective psychosis, and reactive psychosis of early onset: case-control studyPrenatal and perinatal risk factors for early onset schizophrenia, affective psychosis, and reactive psychosis. Bmj. 1999;318(7181):421-6.
- Hultman CM, Sparén P, Cnattingius S. Perinatal risk factors for infantile autism. Epidemiology. 2002;13(4):417-23.
- Lek M, Karczewski KJ, Minikel EV, Samocha KE, Banks E, Fennell T, et al. Analysis of protein-coding genetic variation in 60,706 humans. Nature. 2016;536(7616):285-91.
- Lichtenstein P, Yip BH, Björk C, Pawitan Y, Cannon TD, Sullivan PF, et al. Common genetic determinants of schizophrenia and bipolar disorder in Swedish families: a population-based study. The Lancet. 2009;373(9659):234-9.
- Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P, et al. A polygenic burden of rare disruptive mutations in schizophrenia. Nature. 2014;506(7487):185-90.
- Purcell SM, Wray NR, Stone JL, Visscher PM, O'donovan MC, Sullivan PF, et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature. 2009;460(7256):748-52.
- Ripke S, O'Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, et al. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nature genetics. 2013;45(10):1150-9.
- Stone JL, O’Donovan MC, Gurling H, Kirov GK, Blackwood DH, Corvin A, et al. Rare chromosomal deletions and duplications increase risk of schizophrenia. Nature. 2008;455(7210):237-41.
Pedagogiska meriter
Handledning
Huvudhandledning av doktorander
- Viktoria Johansson, Psychiatrist, Department of Medical Epidemiology and Biostatistics, KI, “Cerebrospinal Fluid Biomarkers in Twins with Schizophrenia and Bipolar Disorder”, 2015
- Sven Sandin, Biostatistician, Maudsley Hospital at Kings’s College, London, UK. ‘Maternal effects in autism’, 2014
- Emma Frans, Biomedical engineer, Department of Medical Epidemiology and Biostatistics, KI, “High paternal age and risk of psychiatric disorders in offspring”, 2013
- Anna Svensson, KTH Bioengineer, Department of Medical Epidemiology and Biostatistics, KI, “Family studies of schizophrenia and pregnancy outcomes”, 2009.
- Erik Wennström, Psychologist, Dept of Neuroscience, Ulleråker, Uppsala, “The Camberwell Assessment of Need as an outcome measure in community mental health care”, 2008.
- James MacCabe, Psychiatrist, Institute of Psychiatry, Psychological Medicine, London, “Educational achievement in schizophrenia and bipolar disorder”, 2007.
- Gabriella Stålberg, Psychologist, Department of Neuroscience, Psychiatry, Ulleråker “Early risk factors and family relations in schizophrenia”. Licentiate thesis, 2004/ Doctorate thesis 2013
Postdocs
- Anna Kähler, Institute of Psychiatry, University of Oslo, and Department of Medical Genetics, Oslo University Hospital, Norway, 2010-2014
- Jacqueline Borg, Clinical Neuroscience, Karolinska Institutet, 2008-2012
- Elin Dianna Gunnarsdottir, University of Akureyri, Iceland, 2008-2009
- Unnur Valdimarsdottir, University of Iceland, Reykjavik, Iceland, 2005-2008
- Carola Åberg, Stockholm University 2005-2006
Utbildning
Utbildning/specialisering
1979 Psych.D./M.Sc, Psychology
1996 Specialist in Clinical Psychology
1996 Specialist in Clinical Research
1996 Licenced Psychotherapist
Doktorsgrad
1996 Ph.D. Uppsala University; Clinical Psychology/Psychiatry; Thesis: Obstetric complications, Electrodermal Activity and Psychosocial Factors within a Stress-Vulnerability Model of Schizophrenia. Supervisor: Professor Arne Öhman, Karolinska Institutet (KI)