Forskningsbeskrivning
Hedin C, van der Gast CJ, Rogers GB, Cuthbertson L, McCartney S, Stagg AJ, Lindsay JO, Whelan K. Siblings of patients with Crohn's disease exhibit a biologically relevant dysbiosis in mucosal microbial metacommunities. Gut. 2016 Jun;65(6):944-53
Hedin CR, McCarthy NE, Louis P, Farquharson FM, McCartney S, Taylor K, Prescott NJ, Murrells T, Stagg AJ, Whelan K, Lindsay JO. Altered intestinal microbiota and blood T cell phenotype are shared by patients with Crohn's disease and their unaffected siblings. Gut. 2014 Oct; 63(10):1578-86
Hedin CRH, Stagg AJ, Whelan K, Lindsay JO. Family studies in Crohn’s disease: New horizons in understanding disease pathogenesis, risk and prevention. Gut 2012; 61: 311-318
Hedin CRH, Mullard M, Sharratt E, Jansen C, Sanderson JD, Shirlaw P, Howe LC, Djemal S, Stagg AJ, Lindsay JO and Whelan K Probiotic and Prebiotic Use in Patients with Inflammatory Bowel Disease: A Case-Control Study. Inflammatory Bowel Diseases 2010; 16(12): 2099-108
Hedin C, Whelan K, Lindsay JO Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials. Proc Nutr Soc 2007; 66 (3): 307-315
McCarthy NE, Hedin CR, Sanders TJ, Amon P, Hoti I, Ayada I, Baji V, Giles EM, Wildemann M, Bashir Z, Whelan K, Sanderson I, Lindsay JO, Stagg AJ. Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn's disease. J Clin Invest. 2015; 125(8):3215-25.
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Prescott NJ, Pessoa-Lopes P, Mathew CG, Sanderson JD, Hart AL, Kamm MA, Knight SC, Forbes A, Stagg AJ, Lindsay JO, Whelan K. Smokers with active Crohn's disease have a clinically relevant dysbiosis of the gastrointestinal microbiota Inflammatory Bowel Diseases 2012; 18(6): 1092–1100
Goodhand J, Hedin CR, Croft NM, Lindsay JO. Adolescents with IBD: The importance of structured transition care. Journal of Crohn's and Colitis 2011; 5(6): 509-519
Benjamin JL, Hedin CRH, Koutsoumpas A, Ng SC, McCarthy NE, Hart AL, Kamm MA, Sanderson JD, Knight SC, Forbes A, Stagg AJ, Whelan K, and Lindsay JO A randomised, double blind placebo controlled trial of fructo-oligosaccharides in active Crohn’s disease. Gut 2011; 60: 923-929
Hedin CRH. In: Smith P, Gill J, Nijjer S, and Levy J, eds. Secrets of Success: Getting into academic training. 1 ed. Royal Society of Medicine Press Ltd, 2010.