Axel Abelein

Axel Abelein

Biträdande Lektor
E-postadress: axel.abelein@ki.se
Besöksadress: Blickagången 16, 14152 Flemingsberg
Postadress: H2 Biovetenskaper och näringslära, H2 BioNut Johansson Abelein, 171 77 Stockholm

Forskningsbeskrivning

  • My research concerns protein self-assembly related to neurodegenerative diseases with the focus on characterization of protein structure and molecular mechanisms of self-assembly. The studies in our lab include a broad range of different techniques within biophysics, protein biochemistry and biomedicine. My current research focuses on the aggregation mechanisms of amyloid-β peptide (Aβ) fibril formation, associated to Alzheimer’s disease and inhibition mechanisms by the BRICHOS domain, a chaperone-like protein that is potential candidate to be implemented in Alzheimer’s disease treatment. Furthermore, another research line is the development of new expression and purification protocols for aggregation-prone proteins using a spider silk-derived solubility tag, where one possible application is the generation of new biomaterials.Please visit our group homepage for more information:https://ki.se/en/bionut/laboratory-for-protein-misfolding-and-assembly

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Anställningar

  • Biträdande Lektor, Medicin, Huddinge, Karolinska Institutet, 2024-2025
  • Biträdande Lektor, Biovetenskaper och näringslära, Karolinska Institutet, 2020-2024

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