Anton Forsberg Morén

Forskningsbeskrivning

My main research is using neuroimaging within neurodegenerative diseases mainly including Alzeimer’s Disease (AD) as well as other neurodegenerative disorders such as Parkinson’s Disease (PD) and Huntington’s Disease (HD). The main method used is Positron Emission Tomography (PET) using various biomarkers for Amyloid, Tau, and radioligands for neuroinflammation, etc.

My first years in PET research included the world first studies of in vivo amyloid PET imaging in mild cognitive impairment (MC) and longitudinal changes of amyloid load in AD. I have after that continued AD research at the Karolinska PET center in Solna including several projects focusing on evaluation and application of novel PET radioligands targeting amyloid and neuroinflammatory targets such as the Translocator protein (TSPO) in microglia. Besides my focus on AD I have been and currently am involved in many other projects including studies of pathological changes in PD investigating the serotonergic and dopaminergic systems and neuroinflammation, as well as developing novel radioligands targeting mutant huntingtin in HD.

During my 19 year long career within PET research I have become an expert in data analysis and modelling of PET data in humans as well as non-human primates. As part of my work here at Karolinska Institutet PET center I have also worked extensively with project management of academic projects as well as collaborations with industrial partners. Therefore my involvement and tasks within this application is clearly connected to both my interests in the research fields as well as my expertise in PET data analysis and project management.

Pedagogiska meriter

Organizer of the one week long research education course “Positron Emission Tomography Imaging of the CNS. Methodology and clinical applications".

Co-organizer of the Master course “Introduction to Brain Imaging in Neuroscience: With a Focus on MRI, PET, EEG and MEG Methods”.