Anoop Tholamplackil Ambikan

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: AIDS. 2023;37(7):1023-1033

Role of myeloid cells in system-level immunometabolic dysregulation during prolonged successful HIV-1 treatment.

Svensson Akusjärvi S; Krishnan S; Ambikan AT; Mikaeloff F; Munusamy Ponnan S; Vesterbacka J; Lourda M; Nowak P; Sönnerborg A; Neogi U
Article: LIFE SCIENCE ALLIANCE. 2022;5(9):e202201405

Genome-scale metabolic models for natural and long-term drug-induced viral control in HIV infection.

Ambikan AT; Svensson-Akusjärvi S; Krishnan S; Sperk M; Nowak P; Vesterbacka J; Sönnerborg A; Benfeitas R; Neogi U
Article: CELL SYSTEMS. 2022;13(8):665-681.e4

Multi-omics personalized network analyses highlight progressive disruption of central metabolism associated with COVID-19 severity.

Ambikan AT; Yang H; Krishnan S; Svensson Akusjärvi S; Gupta S; Lourda M; Sperk M; Arif M; Zhang C; Nordqvist H; Ponnan SM; Sönnerborg A; Treutiger CJ; O'Mahony L; Mardinoglu A; Benfeitas R; Neogi U
Article: ELIFE. 2022;11:e76071

Multi-omics insights into host-viral response and pathogenesis in Crimean-Congo hemorrhagic fever viruses for novel therapeutic target.

Neogi U; Elaldi N; Appelberg S; Ambikan A; Kennedy E; Dowall S; Bagci BK; Gupta S; Rodriguez JE; Svensson-Akusjärvi S; Monteil V; Vegvari A; Benfeitas R; Banerjea A; Weber F; Hewson R; Mirazimi A
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):357

Peripheral blood CD4+CCR6+ compartment differentiates HIV-1 infected or seropositive elite controllers from long-term successfully treated individuals.

Svensson Akusjärvi S; Krishnan S; Jütte BB; Ambikan AT; Gupta S; Rodriguez JE; Végvári Á; Sperk M; Nowak P; Vesterbacka J; Svensson JP; Sönnerborg A; Neogi U
Article: ISCIENCE. 2022;25(1):103607

Integrative proteo-transcriptomic and immunophenotyping signatures of HIV-1 elite control phenotype: A cross-talk between glycolysis and HIF signaling.

Akusjärvi SS; Ambikan AT; Krishnan S; Gupta S; Sperk M; Végvári Á; Mikaeloff F; Healy K; Vesterbacka J; Nowak P; Sönnerborg A; Neogi U
Article: HRB OPEN RESEARCH. 2022;5:31

Impact of Long COVID on health and quality of life.

O' Mahony L; Buwalda T; Blair M; Forde B; Lunjani N; Ambikan A; Neogi U; Barrett P; Geary E; O'Connor N; Dineen J; Clarke G; Kelleher E; Horgan M; Jackson A; Sadlier C
Article: MICROBIOLOGY SPECTRUM. 2021;9(2):e0047021-e00421

Deciphering the Role of Mucosal Immune Responses and the Cervicovaginal Microbiome in Resistance to HIV Infection in HIV-Exposed Seronegative (HESN) Women.

Munusamy Ponnan S; Thiruvengadam K; Tellapragada C; Ambikan AT; Narayanan A; Kathirvel S; Mathayan M; Shankar J; Rajaraman A; Afshan Amanulla M; Dinesha TR; Poongulali S; Saravanan S; Murugavel KG; Swaminathan S; Velu V; Shacklett B; Neogi U; Hanna LE
Article: JOURNAL OF VIROLOGY. 2021;95(18):e0047921-e00421

Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist.

Sperk M; Ambikan AT; Ray S; Singh K; Mikaeloff F; Diez RC; Narayanan A; Vesterbacka J; Nowak P; Sönnerborg A; Neogi U
Article: BMC INFECTIOUS DISEASES. 2021;21(1):214

Increased acquired protease inhibitor drug resistance mutations in minor HIV-1 quasispecies from infected patients suspected of failing on national second-line therapy in South Africa.

Obasa AE; Ambikan AT; Gupta S; Neogi U; Jacobs GB
Article: ISCIENCE. 2021;24(2):102111

Distinct lipid profile, low-level inflammation, and increased antioxidant defense signature in HIV-1 elite control status.

Sperk M; Mikaeloff F; Svensson-Akusjärvi S; Krishnan S; Ponnan SM; Ambikan AT; Nowak P; Sönnerborg A; Neogi U
Article: AIDS. 2021;35(2):227-234

High-throughput sequencing reveals a high prevalence of pretreatment HIV-1 drug resistance in Sweden.

Andersson E; Ambikan A; Brännström J; Aralaguppe SG; Yilmaz A; Albert J; Neogi U; Sönnerborg A
Article: FRONTIERS IN MICROBIOLOGY. 2021;12:627861

Genomic Insights Into Clinical Shiga Toxin-Producing Escherichia coli Strains: A 15-Year Period Survey in Jönköping, Sweden.

Bai X; Zhang J; Hua Y; Jernberg C; Xiong Y; French N; Löfgren S; Hedenström I; Ambikan A; Mernelius S; Matussek A
Article: MOLECULAR & CELLULAR PROTEOMICS. 2021;20:100159

Metabolic Perturbation Associated With COVID-19 Disease Severity and SARS-CoV-2 Replication.

Krishnan S; Nordqvist H; Ambikan AT; Gupta S; Sperk M; Svensson-Akusjärvi S; Mikaeloff F; Benfeitas R; Saccon E; Ponnan SM; Rodriguez JE; Nikouyan N; Odeh A; Ahlén G; Asghar M; Sällberg M; Vesterbacka J; Nowak P; Végvári Á; Sönnerborg A; Treutiger CJ; Neogi U
Article: EMERGING MICROBES & INFECTIONS. 2020;9(1):1748-1760

Dysregulation in Akt/mTOR/HIF-1 signaling identified by proteo-transcriptomics of SARS-CoV-2 infected cells.

Appelberg S; Gupta S; Svensson Akusjärvi S; Ambikan AT; Mikaeloff F; Saccon E; Végvári Á; Benfeitas R; Sperk M; Ståhlberg M; Krishnan S; Singh K; Penninger JM; Mirazimi A; Neogi U
Article: PATHOGENS. 2020;9(5):E320-320

Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs.

Neogi U; Hill KJ; Ambikan AT; Heng X; Quinn TP; Byrareddy SN; Sönnerborg A; Sarafianos SG; Singh K
Article: METABOLITES. 2019;9(10):E210-210

Plasma Metabolic Signature and Abnormalities in HIV-Infected Individuals on Long-Term Successful Antiretroviral Therapy.

Babu H; Sperk M; Ambikan AT; Rachel G; Viswanathan VK; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: VIRUSES-BASEL. 2019;11(9):E806-806

MiDRMpol: A High-Throughput Multiplexed Amplicon Sequencing Workflow to Quantify HIV-1 Drug Resistance Mutations against Protease, Reverse Transcriptase, and Integrase Inhibitors.

Aralaguppe SG; Ambikan AT; Ashokkumar M; Kumar MM; Hanna LE; Amogne W; Sönnerborg A; Neogi U
Article: SCIENTIFIC REPORTS. 2019;9(1):5619

Molecular Characterization and Comparative Genomics of Clinical Hybrid Shiga Toxin-Producing and Enterotoxigenic Escherichia coli (STEC/ETEC) Strains in Sweden.

Bai X; Zhang J; Ambikan A; Jernberg C; Ehricht R; Scheutz F; Xiong Y; Matussek A
Article: FRONTIERS IN MICROBIOLOGY. 2019;10:2632

Effects of the Antimicrobial Peptide LL-37 and Innate Effector Mechanisms in Colistin-Resistant Klebsiella pneumoniae With mgrB Insertions.

Al-Farsi HM; Al-Adwani S; Ahmed S; Vogt C; Ambikan AT; Leber A; Al-Jardani A; Al-Azri S; Al-Muharmi Z; Toprak MS; Giske CG; Bergman P
Article: FRONTIERS IN IMMUNOLOGY. 2019;10:1965

Systemic Inflammation and the Increased Risk of Inflamm-Aging and Age-Associated Diseases in People Living With HIV on Long Term Suppressive Antiretroviral Therapy.

Babu H; Ambikan AT; Gabriel EE; Svensson Akusjärvi S; Palaniappan AN; Sundaraj V; Mupanni NR; Sperk M; Cheedarla N; Sridhar R; Tripathy SP; Nowak P; Hanna LE; Neogi U
Article: EBIOMEDICINE. 2018;27:40-50

Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers.

Zhang W; Ambikan AT; Sperk M; van Domselaar R; Nowak P; Noyan K; Russom A; Sönnerborg A; Neogi U
Article: JOURNAL OF VIROLOGICAL METHODS. 2016;236:98-104

Multiplexed next-generation sequencing and de novo assembly to obtain near full-length HIV-1 genome from plasma virus.

Aralaguppe SG; Siddik AB; Manickam A; Ambikan AT; Kumar MM; Fernandes SJ; Amogne W; Bangaruswamy DK; Hanna LE; Sonnerborg A; Neogi U
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KI thesis / dissertation: 2023

Multi-dimensional omics approaches to dissect natural immune control mechanisms associated with RNA virus infections

Ambikan, Anoop Tholamplackil

Anställningar

Postdoktor, Laboratoriemedicin, Karolinska Institutet, 2023-2025

Examina och utbildning

Medicine Doktorsexamen, Institutionen för laboratoriemedicin, Karolinska Institutet, 2023

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