András Simon

Publikationer
Forskningsbidrag
CV
Populärvetenskap och samverkan

Artiklar

Journal article: DEVELOPMENTAL CELL. 2023;58(24):2819-2821

Understanding the microenvironment and how this controls cell fate.

Fuchs E; Sahai E; Weeraratna AT; Deneen B; Chak-Lui Wong C; Simon A
Journal article: LIFE SCIENCE ALLIANCE. 2023;6(8):e202301979

Evaluation of genetic demultiplexing of single-cell sequencing data from model species.

Cardiello JF; Joven Araus A; Giatrellis S; Helsens C; Simon A; Leigh ND
Article: DEVELOPMENTAL CELL. 2023;58(6):450-460.e6

A small noncoding RNA links ribosome recovery and translation control to dedifferentiation during salamander limb regeneration.

Subramanian E; Elewa A; Brito G; Kumar A; Segerstolpe Å; Karampelias C; Björklund Å; Sandberg R; Echeverri K; Lui W-O; Andersson O; Simon A
Article: NATURE COMMUNICATIONS. 2022;13(1):6949

Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration.

Kaucka M; Joven Araus A; Tesarova M; Currie JD; Boström J; Kavkova M; Petersen J; Yao Z; Bouchnita A; Hellander A; Zikmund T; Elewa A; Newton PT; Fei J-F; Chagin AS; Fried K; Tanaka EM; Kaiser J; Simon A; Adameyko I
Article: SCIENCE. 2022;377(6610):eabp9186

Cell-type profiling in salamanders identifies innovations in vertebrate forebrain evolution.

Woych J; Ortega Gurrola A; Deryckere A; Jaeger ECB; Gumnit E; Merello G; Gu J; Joven Araus A; Leigh ND; Yun M; Simon A; Tosches MA
Article: NATURE CELL BIOLOGY. 2022;24(5):645-658

Epicardium-derived cells organize through tight junctions to replenish cardiac muscle in salamanders.

Eroglu E; Yen CYT; Tsoi Y-L; Witman N; Elewa A; Joven Araus A; Wang H; Szattler T; Umeano CH; Sohlmér J; Goedel A; Simon A; Chien KR
Article: NATURE COMMUNICATIONS. 2022;13(1):1141

Tig1 regulates proximo-distal identity during salamander limb regeneration.

Oliveira CR; Knapp D; Elewa A; Gerber T; Gonzalez Malagon SG; Gates PB; Walters HE; Petzold A; Arce H; Cordoba RC; Subramanian E; Chara O; Tanaka EM; Simon A; Yun MH
Article: NATURE COMMUNICATIONS. 2021;12(1):4857

Locomotion dependent neuron-glia interactions control neurogenesis and regeneration in the adult zebrafish spinal cord.

Chang W; Pedroni A; Bertuzzi M; Kizil C; Simon A; Ampatzis K
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2021;78(16):6033-6049

Nerve-associated Schwann cell precursors contribute extracutaneous melanocytes to the heart, inner ear, supraorbital locations and brain meninges.

Kaucka M; Szarowska B; Kavkova M; Kastriti ME; Kameneva P; Schmidt I; Peskova L; Joven Araus A; Simon A; Kaiser J; Adameyko I
Article: JOURNAL OF NEUROSCIENCE METHODS. 2021;348:109002

CUBIC-f: An optimized clearing method for cell tracing and evaluation of neurite density in the salamander brain.

Pinheiro T; Mayor I; Edwards S; Joven A; Kantzer CG; Kirkham M; Simon A
Article: ELIFE. 2020;9:e55212

Secondary ossification center induces and protects growth plate structure.

Xie M; Gol'din P; Herdina AN; Estefa J; Medvedeva EV; Li L; Newton PT; Kotova S; Shavkuta B; Saxena A; Shumate LT; Metscher BD; Großschmidt K; Nishimori S; Akovantseva A; Usanova AP; Kurenkova AD; Kumar A; Arregui IL; Tafforeau P; Fried K; Carlström M; Simon A; Gasser C; Kronenberg HM; Bastepe M; Cooper KL; Timashev P; Sanchez S; Adameyko I; Eriksson A; Chagin AS
Article: DEVELOPMENT. 2019;146(14):dev167700

Model systems for regeneration: salamanders.

Joven A; Elewa A; Simon A
Article: SCIENTIFIC REPORTS. 2018;8(1):14145

A quantitative analysis of 3D-cell distribution in regenerating muscle-skeletal system with synchrotron X-ray computed microtomography.

Tesařová M; Mancini L; Simon A; Adameyko I; Kaucká M; Elewa A; Lanzafame G; Zhang Y; Kalasová D; Szarowská B; Zikmund T; Novotná M; Kaiser J
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2018;499(2):136-142

Reprint of: A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.

Pinheiro T; Otrocka M; Seashore-Ludlow B; Rraklli V; Holmberg J; Forsberg-Nilsson K; Simon A; Kirkham M
Article: DEVELOPMENT. 2018;145(1):dev160051

Cellular basis of brain maturation and acquisition of complex behaviors in salamanders.

Joven A; Wang H; Pinheiro T; Hameed LS; Belnoue L; Simon A
Article: NATURE COMMUNICATIONS. 2017;8(1):2286

Reading and editing the Pleurodeles waltl genome reveals novel features of tetrapod regeneration.

Elewa A; Wang H; Talavera-López C; Joven A; Brito G; Kumar A; Hameed LS; Penrad-Mobayed M; Yao Z; Zamani N; Abbas Y; Abdullayev I; Sandberg R; Grabherr M; Andersson B; Simon A
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2017;494(3-4):477-483

A chemical screen identifies trifluoperazine as an inhibitor of glioblastoma growth.

Pinheiro T; Otrocka M; Seashore-Ludlow B; Rraklli V; Holmberg J; Forsberg-Nilsson K; Simon A; Kirkham M
Article: DEVELOPMENTAL CELL. 2017;40(6):608-617.e6

Serum Proteases Potentiate BMP-Induced Cell Cycle Re-entry of Dedifferentiating Muscle Cells during Newt Limb Regeneration.

Wagner I; Wang H; Weissert PM; Straube WL; Shevchenko A; Gentzel M; Brito G; Tazaki A; Oliveira C; Sugiura T; Shevchenko A; Simon A; Drechsel DN; Tanaka EM
Article: CURRENT OPINION IN GENETICS & DEVELOPMENT. 2016;40:108-112

Skeletal muscle dedifferentiation during salamander limb regeneration.

Wang H; Simon A
Article: SCIENTIFIC REPORTS. 2016;6:26448

Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.

Hedlund E; Belnoue L; Theofilopoulos S; Salto C; Bye C; Parish C; Deng Q; Kadkhodaei B; Ericson J; Arenas E; Perlmann T; Simon A
Article: NATURE. 2016;531(7593):237-240

MARCKS-like protein is an initiating molecule in axolotl appendage regeneration.

Sugiura T; Wang H; Barsacchi R; Simon A; Tanaka EM
Article: ELIFE. 2015;4:e08422

Environmental changes in oxygen tension reveal ROS-dependent neurogenesis and regeneration in the adult newt brain.

Hameed LS; Berg DA; Belnoue L; Jensen LD; Cao Y; Simon A
Article: NATURE COMMUNICATIONS. 2015;6:7916

Turning terminally differentiated skeletal muscle cells into regenerative progenitors.

Wang H; Lööf S; Borg P; Nader GA; Blau HM; Simon A
Article: PLOS ONE. 2015;10(3):e0120176

Sublethal caspase activation promotes generation of cardiomyocytes from embryonic stem cells.

Bulatovic I; Ibarra C; Österholm C; Wang H; Beltrán-Rodríguez A; Varas-Godoy M; Månsson-Broberg A; Uhlén P; Simon A; Grinnemo K-H
Article: METHODS IN MOLECULAR BIOLOGY. 2015;1290:197-204

Isolation and culture of neurospheres from the adult newt brain.

Hameed LAS; Simon A
Article: METHODS IN MOLECULAR BIOLOGY. 2015;1290:47-70

Husbandry of Spanish ribbed newts (Pleurodeles waltl).

Joven A; Kirkham M; Simon A
Article: STEM CELL REPORTS. 2014;2(4):507-519

Progenitor cell dynamics in the Newt Telencephalon during homeostasis and neuronal regeneration.

Kirkham M; Hameed LS; Berg DA; Wang H; Simon A
Article: CELL STEM CELL. 2014;14(2):174-187

Fundamental differences in dedifferentiation and stem cell recruitment during skeletal muscle regeneration in two salamander species.

Sandoval-Guzmán T; Wang H; Khattak S; Schuez M; Roensch K; Nacu E; Tazaki A; Joven A; Tanaka EM; Simon A
Article: EXPERIMENTAL CELL RESEARCH. 2013;319(8):1187-1197

A reference transcriptome and inferred proteome for the salamander Notophthalmus viridescens.

Abdullayev I; Kirkham M; Björklund ÅK; Simon A; Sandberg R
Article: WILEY INTERDISCIPLINARY REVIEWS: DEVELOPMENTAL BIOLOGY. 2013;2(2):291-300

Limb regeneration.

Simon A; Tanaka EM
Article: NEUROSCIENCE LETTERS. 2011;497(1):11-16

Microglia activation during neuroregeneration in the adult vertebrate brain.

Kirkham M; Berg DA; Simon A
Article: CELL STEM CELL. 2011;8(4):426-433

Dopamine controls neurogenesis in the adult salamander midbrain in homeostasis and during regeneration of dopamine neurons.

Berg DA; Kirkham M; Wang H; Frisén J; Simon A
Journal article: DEVELOPMENT. 2011;138(1):180

Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain

Berg DA; Kirkham M; Beljajeva A; Knapp D; Habermann B; Ryge J; Tanaka EM; Simon A
Article: DEVELOPMENT. 2010;137(24):4127-4134

Efficient regeneration by activation of neurogenesis in homeostatically quiescent regions of the adult vertebrate brain.

Berg DA; Kirkham M; Beljajeva A; Knapp D; Habermann B; Ryge J; Tanaka EM; Simon A
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2010;223(2):376-383

Myogenic skeletal muscle satellite cells communicate by tunnelling nanotubes.

Tavi P; Korhonen T; Hänninen SL; Bruton JD; Lööf S; Simon A; Westerblad H
Article: FASEB JOURNAL. 2010;24(3):750-756

Plasticity and recovery of skeletal muscle satellite cells during limb regeneration.

Morrison JI; Borg P; Simon A
Article: DEVELOPMENT. 2007;134(15):2881-2887

Midbrain dopaminergic neurogenesis and behavioural recovery in a salamander lesion-induced regeneration model.

Parish CL; Beljajeva A; Arenas E; Simon A
Article: CELL CYCLE. 2007;6(9):1096-1101

Plasticity of mammalian myotubes upon stimulation with a thrombin-activated serum factor.

Lööf S; Straube WL; Drechsel D; Tanaka EM; Simon A
Article: DEVELOPMENTAL DYNAMICS. 2007;236(2):481-488

Targeted gene delivery to differentiated skeletal muscle: a tool to study dedifferentiation.

Morrison JI; Lööf S; He P; Aleström P; Collas P; Simon A
Article: JOURNAL OF CELL BIOLOGY. 2006;172(3):433-440

Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population.

Morrison JI; Lööf S; He P; Simon A
Article: PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES. 2004;359(1445):765-776

A critical role for thrombin in vertebrate lens regeneration.

Imokawa Y; Simon A; Brockes JP
Article: EXPERIMENTAL CELL RESEARCH. 2002;281(1):101-106

Thrombin activation of S-phase reentry by cultured pigmented epithelial cells of adult newt iris.

Simon A; Brockes JP
Article: CURRENT BIOLOGY. 2001;11(11):855-858

Mammalian postmitotic nuclei reenter the cell cycle after serum stimulation in newt/mouse hybrid myotubes.

Velloso CP; Simon A; Brockes JP
Article: NATURE GENETICS. 1999;22(2):188-191

Mutations in the gene encoding 11-cis retinol dehydrogenase cause delayed dark adaptation and fundus albipunctatus.

Yamamoto H; Simon A; Eriksson U; Harris E; Berson EL; Dryja TP
Article: JOURNAL OF CELL SCIENCE. 1999;112 ( Pt 4):549-558

Intracellular localization and membrane topology of 11-cis retinol dehydrogenase in the retinal pigment epithelium suggest a compartmentalized synthesis of 11-cis retinaldehyde.

Simon A; Romert A; Gustafson AL; McCaffery JM; Eriksson U
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 1998;95(8):4404-4409

The identification of a 9-cis retinol dehydrogenase in the mouse embryo reveals a pathway for synthesis of 9-cis retinoic acid.

Romert A; Tuvendal P; Simon A; Dencker L; Eriksson U
Article: GENOMICS. 1996;36(3):424-430

Primary structure of human 11-cis retinol dehydrogenase and organization and chromosomal localization of the corresponding gene.

Simon A; Lagercrantz J; Bajalica-Lagercrantz S; Eriksson U
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1995;270(3):1107-1112

The retinal pigment epithelial-specific 11-cis retinol dehydrogenase belongs to the family of short chain alcohol dehydrogenases.

Simon A; Hellman U; Wernstedt C; Eriksson U
Journal article: NEUROSCIENCE. 1994;62(3):899-918

Localization of cellular retinoid-binding proteins suggests specific roles for retinoids in the adult central nervous system.

Zetterström RH; Simon A; Giacobini MM; Eriksson U; Olson L
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Alla övriga publikationer

Preprint: RES SQ. 2023;RES SQ

Macrophages modulate fibrosis during newt lens regeneration.

Tsissios G; Sallese A; Perez-Estrada JR; Tangeman JA; Chen W; Smucker B; Ratvasky SC; Grajales-Esquive EL; Martinez A; Visser KJ; Araus AJ; Wang H; Simon A; Yun MH; Rio-Tsonis KD
Preprint: BIORXIV. 2023;BIORXIV

Macrophages modulate fibrosis during newt lens regeneration.

Tsissios G; Sallese A; Perez-Estrada JR; Tangeman JA; Chen W; Smucker B; Ratvasky SC; Grajales-Esquivel E; Martinez A; Visser KJ; Araus AJ; Wang H; Simon A; Yun MH; Rio-Tsonis KD
Preprint: 2022;bioRxiv

Sequencing and chromosome-scale assembly of the giant Pleurodeles waltl genome

Brown T; Elewa A; Iarovenko S; Subramanian E; Araus AJ; Petzold A; Suzuki M; Suzuki K-IT; Hayashi T; Toyoda A; Oliveira C; Osipova E; Leigh ND; Simon A; Yun MH
Preprint: 2022;bioRxiv

Accurate genotype-based demultiplexing of single cell RNA sequencing samples from non-human animals

Cardiello JF; Araus AJ; Giatrellis S; Simon A; Leigh ND
Corrigendum: NATURE COMMUNICATIONS. 2022;13(1):4507

Publisher Correction: Tig1 regulates proximo-distal identity during salamander limb regeneration.

Oliveira CR; Knapp D; Elewa A; Gerber T; Gonzalez Malagon SG; Gates PB; Walters HE; Petzold A; Arce H; Cordoba RC; Subramanian E; Chara O; Tanaka EM; Simon A; Yun MH
Letter: DEVELOPMENTAL DYNAMICS. 2022;251(6):911-912

Standardized gene and genetic nomenclature for the newt Pleurodeles waltl.

Yun MH; Hayashi T; Simon A
Preprint: 2022;bioRxiv

Cell type profiling in salamanders identifies innovations in vertebrate forebrain evolution

Woych J; Gurrola AO; Deryckere A; Jaeger ECB; Gumnit E; Merello G; Gu J; Araus AJ; Leigh ND; Yun M; Simon A; Tosches MA
Preprint: 2022;bioRxiv

Telomerase-independent maintenance of telomere length in a vertebrate

Yu Q; Gates PB; Rogers S; Mikicic I; Elewa A; Salomon F; Lachnit M; Caldarelli A; Flores-Rodriguez N; Cesare AJ; Simon A; Yun MH
Preprint: 2021;bioRxiv

Tig1 regulates proximo-distal identity during salamander limb regeneration

Oliveira CR; Knapp D; Elewa A; Gerber T; Malagon SGG; Gates PB; Walters HE; Petzold A; Arce H; Cordoba RC; Subramanian E; Chara O; Tanaka EM; Simon A; Yun MH
Review: TRENDS IN NEUROSCIENCES. 2020;43(11):916-930

Walking with Salamanders: From Molecules to Biorobotics.

Ryczko D; Simon A; Ijspeert AJ
Corrigendum: SCIENTIFIC REPORTS. 2020;10(1):2276

Author Correction: A quantitative analysis of 3D-cell distribution in regenerative muscle-skeletal system with synchrotron X-ray computed microtomography.

Tesařová M; Mancini L; Simon A; Adameyko I; Kaucká M; Elewa A; Lanzafame G; Zhang Y; Kalasová D; Szarowská B; Zikmund T; Novotná M; Kaiser J
Preprint: 2019;bioRxiv

Secondary ossification center induces and protects growth plate structure

Xie M; Gol’din P; Herdina AN; Estefa J; Medvedeva EV; Li L; Newton PT; Kotova S; Shavkuta B; Saxena A; Shumate LT; Metscher B; Großschmidt K; Nishimori S; Akovantseva A; Usanova AP; Kurenkova AD; Kumar A; Arregui IL; Tafforeau P; Fried K; Carlström M; Simon A; Gasser C; Kronenberg HM; Bastepe M; Cooper KL; Timashev P; Sanchez S; Adameyko I; Eriksson A; Chagin AS
Review: PROGRESS IN NEUROBIOLOGY. 2018;170:81-98

Homeostatic and regenerative neurogenesis in salamanders.

Joven A; Simon A
Editorial comment: EXPERIMENTAL CELL RESEARCH. 2018;370(2):189

Changing master regulator without reprogramming.

Lendahl U; Simon A
Other: DEVELOPMENTAL BIOLOGY. 2018;433(2):115-117

Dr. Panagiotis (Takis) Tsonis: A man for all seasons In Memoriam

Simon A; Voss SR; Alvarado AS
Editorial comment: NATURE. 2013;500(7460):32-33

Regenerative biology: On with their heads.

Simon A
Review: DEVELOPMENT. 2013;140(12):2548-2561

Neurotransmitter-mediated control of neurogenesis in the adult vertebrate brain.

Berg DA; Belnoue L; Song H; Simon A
Review: SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2009;20(6):691-696

Not lost in translation Sensing the loss and filling the gap during regeneration.

Simon A; Berg D; Kirkham M
Editorial comment: CELLULAR AND MOLECULAR LIFE SCIENCES. 2008;65(1):3-7

Regeneration and tissue repair: themes and variations.

Galliot B; Tanaka E; Simon A
Editorial comment: CELL. 2007;128(5):825-826

From stem cell to progenitor and back again.

Simon A; Frisén J
Conference publication: MECHANISMS OF DEVELOPMENT. 2005;122:S133

Neurogenesis and functional recovery in Parkinsonian newts

Parish CL; Beljajeva A; Arenas E; Simon A
Editorial comment: SCANDINAVIAN JOURNAL OF LABORATORY ANIMAL SCIENCE. 2001;28(4):241-242

Meet a research group: Andras Simon, CMB, KI

Simon A
Review: RECOMBINANT PROTEIN EXPRESSION: PROKARYOTIC HOSTS AND CELL-FREE SYSTEMS. 2000;316:344-358

Analyzing membrane topology of 11-cis-retinol dehydrogenase.

Simon A; Romert A; Eriksson U
Conference publication: MOLECULAR BIOLOGY OF THE CELL. 1996;7:3461

Cloning and characterization of two membrane proteins participating in retinoid transport and metabolism in the eye

Simon A; Berrez JM; Gustafson AL; Eriksson U
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Forskningsbidrag

Reversible cell state transitions during vertebrate regeneration

Swedish Research Council

1 January 2024 - 31 December 2027
Stem cells at the interface of regeneration and tumor biology – lessons from salamanders

Cancerfonden

1 January 2023 - 31 December 2026
SALAMANDRA

European Research Council

1 September 2021 - 31 August 2027
Regeneration mechanisms in the adult brain

Swedish Research Council

1 January 2019 - 31 December 2022
Refining methods in salamander research

Swedish Research Council

1 January 2018 - 31 December 2021
Capturing the regenerative potential of the brain

Knut and Alice Wallenberg Foundation

1 January 2018 - 1 January 2023
Joint BSDB/Nordic Meeting on Development and Regeneration

Swedish Research Council

1 June 2017 - 30 June 2017
Mechanisms of cell plasticity during limb regeneration in adult vertebrates

Swedish Research Council

1 January 2015 - 31 December 2018
Cross-species comparisons of adult neurogenesis and neuroregeneration.

Swedish Research Council

1 January 2015 - 31 December 2018
BRAINGAIN

European Research Council

1 February 2012 - 31 January 2017
Understanding adult neurogenesis and neuroregeneration

Swedish Research Council

1 January 2012 - 31 December 2014
Dynamics of skleletal muscle cells during limb regeneration in adult vertebrates

Swedish Research Council

1 January 2012 - 31 December 2013
Sensing the loss and filling the gap during regeneration

Swedish Research Council

1 January 2011 - 31 December 2016
A high resolution mass spectrometer with multiple ionization functionality for research in metabolomics and proteomics

Swedish Research Council

1 January 2009 - 31 October 2014

Anställningar

Professor, Cell- och molekylärbiologi, Karolinska Institutet, 2014-

Examina och utbildning

Docent, Cell och molekylärbiologi, Karolinska Institutet, 2010

Uppdrag

Prefekt, C5 Cell- och molekylärbiologi, Karolinska Institutet, 2021-

Uppdrag i kommitté

Medlem, Nobel Assembly, 2022

Redaktör för vetenskaplig tidskrift

Experimental Cell Research, Chefredaktör, 2018

Artiklar

Alla övriga publikationer

Forskningsbidrag

Anställningar

Examina och utbildning

Uppdrag

Uppdrag i kommitté

Redaktör för vetenskaplig tidskrift

Nyheter från KI

Kalenderhändelser från KI