Alina Castell

Publikationer
Populärvetenskap och samverkan

Artiklar

Article: ONCOTARGET. 2016;7(3):2837-2854

Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation.

Bahram F; Hydbring P; Tronnersjö S; Zakaria SM; Frings O; Fahlén S; Nilsson H; Goodwin J; von der Lehr N; Su Y; Lüscher B; Castell A; Larsson L-G
Article: ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY. 2015;71(Pt 11):2297-2308

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.

Bashiri G; Johnston JM; Evans GL; Bulloch EMM; Goldstone DC; Jirgis ENM; Kleinboelting S; Castell A; Ramsay RJ; Manos-Turvey A; Payne RJ; Lott JS; Baker EN
Article: BIOCHEMISTRY. 2015;54(39):6082-6092

Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.

Cookson TVM; Evans GL; Castell A; Baker EN; Lott JS; Parker EJ
Article: BIOCHEMICAL JOURNAL. 2014;461(1):87-98

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.

Cookson TVM; Castell A; Bulloch EMM; Evans GL; Short FL; Baker EN; Lott JS; Parker EJ
Article: BIOCHEMISTRY. 2013;52(10):1776-1787

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition.

Castell A; Short FL; Evans GL; Cookson TVM; Bulloch EMM; Joseph DDA; Lee CE; Parker EJ; Baker EN; Lott JS
Article: ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY. 2010;66(Pt 5):549-557

Structural analysis of mycobacterial branched-chain aminotransferase: implications for inhibitor design.

Castell A; Mille C; Unge T
Article: PROTEIN SCIENCE. 2006;15(10):2300-2309

Structure and function of Rv0130, a conserved hypothetical protein from Mycobacterium tuberculosis.

Johansson P; Castell A; Jones TA; Bäckbro K
Article: PROTEIN SCIENCE. 2005;14(7):1850-1862

Rv0216, a conserved hypothetical protein from Mycobacterium tuberculosis that is essential for bacterial survival during infection, has a double hotdog fold.

Castell A; Johansson P; Unge T; Jones TA; Bäckbro K
Article: MOLECULAR CANCER RESEARCH. 2004;2(8):464-476

Mad 1 inhibits cell growth and proliferation but does not promote differentiation or overall survival in human U-937 monoblasts.

Hultquist A; Cetinkaya C; Wu S; Castell A; Erlandsson A; Larsson L-G
Article: MOLECULAR CELL. 2003;11(5):1189-1200

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription.

von der Lehr N; Johansson S; Wu S; Bahram F; Castell A; Cetinkaya C; Hydbring P; Weidung I; Nakayama K; Nakayama KI; Söderberg O; Kerppola TK; Larsson L-G

Alla övriga publikationer

Review: GENES. 2017;8(7):E174-174

MYC Modulation around the CDK2/p27/SKP2 Axis.

Hydbring P; Castell A; Larsson L-G
Editorial comment: CANCER DISCOVERY. 2015;5(7):701-703

Targeting MYC Translation in Colorectal Cancer.

Castell A; Larsson L-G

Artiklar

Alla övriga publikationer

Nyheter från KI

Kalenderhändelser från KI