Alexander Chibalin

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Journal article: JOURNAL OF MEMBRANE BIOLOGY. 2021;254(5-6):531-548

Phosphorylation of Na+,K+-ATPase at Tyr10 of the α1-Subunit is Suppressed by AMPK and Enhanced by Ouabain in Cultured Kidney Cells.

Petrič M; Vidović A; Dolinar K; Miš K; Chibalin AV; Pirkmajer S
Article: DIABETOLOGIA. 2021;64(7):1642-1659

Exercise training improves mitochondrial respiration and is associated with an altered intramuscular phospholipid signature in women with obesity.

Mendham AE; Goedecke JH; Zeng Y; Larsen S; George C; Hauksson J; Fortuin-de Smidt MC; Chibalin AV; Olsson T; Chorell E
Article: METABOLISM-CLINICAL AND EXPERIMENTAL. 2021;118:154726

Quantitative phosphoproteomic analysis of IRS1 in skeletal muscle from men with normal glucose tolerance or type 2 diabetes: A case-control study.

Karlsson HKR; Kasahara A; Ikeda M; Chibalin AV; Harada J; Rydén M; Krook A; Kato M; Kubota K; Zierath JR
Article: PLOS ONE. 2021;16(2):e0247377

Effect of differentiation, de novo innervation, and electrical pulse stimulation on mRNA and protein expression of Na+,K+-ATPase, FXYD1, and FXYD5 in cultured human skeletal muscle cells.

Jan V; Miš K; Nikolic N; Dolinar K; Petrič M; Bone A; Thoresen GH; Rustan AC; Marš T; Chibalin AV; Pirkmajer S
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2020;318(5):C1030-C1041

Isoform-specific Na,K-ATPase and membrane cholesterol remodeling in motor endplates in distinct mouse models of myodystrophy.

Kravtsova VV; Bouzinova EV; Chibalin AV; Matchkov VV; Krivoi II
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2020;318(3):C615-C626

Comparative profiling of skeletal muscle models reveals heterogeneity of transcriptome and metabolism.

Abdelmoez AM; Sardón Puig L; Smith JAB; Gabriel BM; Savikj M; Dollet L; Chibalin AV; Krook A; Zierath JR; Pillon NJ
Article: FRONTIERS IN PHYSIOLOGY. 2020;11:566584

Ouabain Suppresses IL-6/STAT3 Signaling and Promotes Cytokine Secretion in Cultured Skeletal Muscle Cells.

Pirkmajer S; Bezjak K; Matkovič U; Dolinar K; Jiang LQ; Miš K; Gros K; Milovanova K; Pirkmajer KP; Marš T; Kapilevich L; Chibalin AV
Article: DIABETES RESEARCH AND CLINICAL PRACTICE. 2019;158:107928

Low AS160 and high SGK basal phosphorylation associates with impaired incretin profile and type 2 diabetes in adipose tissue of obese patients.

Stafeev IS; Sklyanik IA; Yah'yaev KA; Shestakova EA; Yurasov AV; Karmadonov AV; Chibalin AV; Yu Menshikov M; Vorotnikov AV; Parfyonova YV; Shestakova MV
Article: FASEB JOURNAL. 2019;33(9):10551-10562

Secreted protein acidic and rich in cysteine (SPARC) improves glucose tolerance via AMP-activated protein kinase activation.

Aoi W; Hirano N; Lassiter DG; Björnholm M; Chibalin AV; Sakuma K; Tanimura Y; Mizushima K; Takagi T; Naito Y; Zierath JR; Krook A
Article: DIABETES. 2019;68(7):1403-1414

Modified UCN2 Peptide Acts as an Insulin Sensitizer in Skeletal Muscle of Obese Mice.

Borg ML; Massart J; Schönke M; De Castro Barbosa T; Guo L; Wade M; Alsina-Fernandez J; Miles R; Ryan A; Bauer S; Coskun T; O'Farrell E; Niemeier EM; Chibalin AV; Krook A; Karlsson HK; Brozinick JT; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2018;315(6):C803-C817

Nucleosides block AICAR-stimulated activation of AMPK in skeletal muscle and cancer cells.

Dolinar K; Jan V; Pavlin M; Chibalin AV; Pirkmajer S
Article: CELL CALCIUM. 2018;76:72-86

Transcriptomic changes in C2C12 myotubes triggered by electrical stimulation: Role of Ca2+i-mediated and Ca2+i-independent signaling and elevated [Na+]i/[K+]i ratio.

Sidorenko S; Klimanova E; Milovanova K; Lopina OD; Kapilevich LV; Chibalin AV; Orlov SN
Article: JOURNAL OF CELLULAR PHYSIOLOGY. 2018;233(10):6329-6336

Early endplate remodeling and skeletal muscle signaling events following rat hindlimb suspension.

Chibalin AV; Benziane B; Zakyrjanova GF; Kravtsova VV; Krivoi II
Article: ACTA PHYSIOLOGICA. 2018;224(1):e13059

The α2 isoform Na,K-ATPase modulates contraction of rat mesenteric small artery via cSrc-dependent Ca2+ sensitization.

Bouzinova EV; Hangaard L; Staehr C; Mazur A; Ferreira A; Chibalin AV; Sandow SL; Xie Z; Aalkjaer C; Matchkov VV
Article: SCIENCE ADVANCES. 2018;4(8):eaar8590

Acute sleep loss results in tissue-specific alterations in genome-wide DNA methylation state and metabolic fuel utilization in humans.

Cedernaes J; Schönke M; Westholm JO; Mi J; Chibalin A; Voisin S; Osler M; Vogel H; Hörnaeus K; Dickson SL; Lind SB; Bergquist J; Schiöth HB; Zierath JR; Benedict C
Article: ACTA PHYSIOLOGICA. 2018;223(3):e13051

Protein translation, proteolysis and autophagy in human skeletal muscle atrophy after spinal cord injury.

Lundell LS; Savikj M; Kostovski E; Iversen PO; Zierath JR; Krook A; Chibalin AV; Widegren U
Article: PROTEOMICS. 2018;18(5-6):e1700375

Proteomics Analysis of Skeletal Muscle from Leptin-Deficient ob/ob Mice Reveals Adaptive Remodeling of Metabolic Characteristics and Fiber Type Composition.

Schönke M; Björnholm M; Chibalin AV; Zierath JR; Deshmukh AS
Article: DIABETOLOGIA. 2018;61(2):424-432

FAK tyrosine phosphorylation is regulated by AMPK and controls metabolism in human skeletal muscle.

Lassiter DG; Nylén C; Sjögren RJO; Chibalin AV; Wallberg-Henriksson H; Näslund E; Krook A; Zierath JR
Article: JOURNAL OF LIPID RESEARCH. 2018;59(2):273-282

Diacylglycerol kinase α deficiency alters inflammation markers in adipose tissue in response to a high-fat diet.

Nascimento EBM; Mannerås-Holm L; Chibalin AV; Björnholm M; Zierath JR
Article: JOURNAL OF LIPID RESEARCH. 2017;58(12):2324-2333

DGKζ deficiency protects against peripheral insulin resistance and improves energy metabolism.

Benziane B; Borg ML; Tom RZ; Riedl I; Massart J; Björnholm M; Gilbert M; Chibalin AV; Zierath JR
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2017;595(14):4611-4630

Early vertebrate origin and diversification of small transmembrane regulators of cellular ion transport.

Pirkmajer S; Kirchner H; Lundell LS; Zelenin PV; Zierath JR; Makarova KS; Wolf YI; Chibalin AV
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2017;312(5):C627-C637

Membrane lipid rafts are disturbed in the response of rat skeletal muscle to short-term disuse.

Petrov AM; Kravtsova VV; Matchkov VV; Vasiliev AN; Zefirov AL; Chibalin AV; Heiny JA; Krivoi II
Article: JOURNAL OF LIPID RESEARCH. 2017;58(5):907-915

Diacylglycerol kinase ε deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice.

Mannerås-Holm L; Schönke M; Brozinick JT; Vetterli L; Bui H-H; Sanders P; Nascimento EBM; Björnholm M; Chibalin AV; Zierath JR
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2016;45(5):347-355

Methotrexate reduces HbA1c concentration but does not produce chronic accumulation of ZMP in patients with rheumatoid or psoriatic arthritis.

Perdan-Pirkmajer K; Pirkmajer S; Thevis M; Thomas A; Praprotnik S; Hočevar A; Rotar Ž; Gašperšič N; Sodin-Šemrl S; Žibert J; Omersel J; Chibalin AV; Tomšič M; Ambrožič A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2016;310(6):E461-E472

AMPKγ3 is dispensable for skeletal muscle hypertrophy induced by functional overload.

Riedl I; Osler ME; Björnholm M; Egan B; Nader GA; Chibalin AV; Zierath JR
Article: JOURNAL OF GENERAL PHYSIOLOGY. 2016;147(2):175-188

Distinct α2 Na,K-ATPase membrane pools are differently involved in early skeletal muscle remodeling during disuse.

Kravtsova VV; Petrov AM; Matchkov VV; Bouzinova EV; Vasiliev AN; Benziane B; Zefirov AL; Chibalin AV; Heiny JA; Krivoi II
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2016;310(1):E51-E60

Diacylglycerol kinase-δ regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics.

Jiang LQ; de Castro Barbosa T; Massart J; Deshmukh AS; Löfgren L; Duque-Guimaraes DE; Ozilgen A; Osler ME; Chibalin AV; Zierath JR
Article: PHYSIOLOGICAL REPORTS. 2015;3(11):e12622

MicroRNA-208b progressively declines after spinal cord injury in humans and is inversely related to myostatin expression.

Boon H; Sjögren RJO; Massart J; Egan B; Kostovski E; Iversen PO; Hjeltnes N; Chibalin AV; Widegren U; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2015;309(4):E388-E397

Effect of N-acetylcysteine infusion on exercise-induced modulation of insulin sensitivity and signaling pathways in human skeletal muscle.

Trewin AJ; Lundell LS; Perry BD; Patil KV; Chibalin AV; Levinger I; McQuade LR; Stepto NK
Article: PHYSIOLOGICAL REPORTS. 2015;3(4):e12372

mRNA expression of diacylglycerol kinase isoforms in insulin-sensitive tissues: effects of obesity and insulin resistance.

Mannerås-Holm L; Kirchner H; Björnholm M; Chibalin AV; Zierath JR
Article: PHYSIOLOGICAL REPORTS. 2015;3(3):e12314

Association of the ACTN3 R577X polymorphism with glucose tolerance and gene expression of sarcomeric proteins in human skeletal muscle.

Riedl I; Osler ME; Benziane B; Chibalin AV; Zierath JR
Article: DIABETES. 2015;64(2):360-369

Methotrexate promotes glucose uptake and lipid oxidation in skeletal muscle via AMPK activation.

Pirkmajer S; Kulkarni SS; Tom RZ; Ross FA; Hawley SA; Hardie DG; Zierath JR; Chibalin AV
Article: BMC RESEARCH NOTES. 2014;7:391

A simple and rapid method to characterize lipid fate in skeletal muscle.

Massart J; Zierath JR; Chibalin AV
Article: DIABETES. 2014;63(5):1560-1571

Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice.

Zachariah Tom R; Garcia-Roves PM; Sjögren RJO; Jiang LQ; Holmström MH; Deshmukh AS; Vieira E; Chibalin AV; Björnholm M; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2013;305(9):E1071-E1080

Altered content of AMP-activated protein kinase isoforms in skeletal muscle from spinal cord injured subjects.

Kostovski E; Boon H; Hjeltnes N; Lundell LS; Ahlsén M; Chibalin AV; Krook A; Iversen PO; Widegren U
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2013;591(18):4637-4653

Regulation of miRNAs in human skeletal muscle following acute endurance exercise and short-term endurance training.

Russell AP; Lamon S; Boon H; Wada S; Güller I; Brown EL; Chibalin AV; Zierath JR; Snow RJ; Stepto N; Wadley GD; Akimoto T
Article: DIABETOLOGIA. 2013;56(9):2044-2054

LXR is a negative regulator of glucose uptake in human adipocytes.

Pettersson AML; Stenson BM; Lorente-Cebrián S; Andersson DP; Mejhert N; Krätzel J; Aström G; Dahlman I; Chibalin AV; Arner P; Laurencikiene J
Article: DIABETES. 2013;62(2):457-465

Constitutive STAT3 phosphorylation contributes to skeletal muscle insulin resistance in type 2 diabetes.

Mashili F; Chibalin AV; Krook A; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2012;303(4):E524-E533

The Rab-GTPase-activating protein TBC1D1 regulates skeletal muscle glucose metabolism.

Szekeres F; Chadt A; Tom RZ; Deshmukh AS; Chibalin AV; Björnholm M; Al-Hasani H; Zierath JR
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2012;287(28):23451-23463

Activation of AMP-activated protein kinase stimulates Na+,K+-ATPase activity in skeletal muscle cells.

Benziane B; Björnholm M; Pirkmajer S; Austin RL; Kotova O; Viollet B; Zierath JR; Chibalin AV
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2012;302(7):E864-E871

Influence of chronic and acute spinal cord injury on skeletal muscle Na+-K+-ATPase and phospholemman expression in humans.

Boon H; Kostovski E; Pirkmajer S; Song M; Lubarski I; Iversen PO; Hjeltnes N; Widegren U; Chibalin AV
Article: PLOS ONE. 2012;7(12):e53080

Short-term intensified cycle training alters acute and chronic responses of PGC1α and Cytochrome C oxidase IV to exercise in human skeletal muscle.

Stepto NK; Benziane B; Wadley GD; Chibalin AV; Canny BJ; Eynon N; McConell GK
Article: PLOS ONE. 2012;7(3):e33719

Chronic nicotine modifies skeletal muscle Na,K-ATPase activity through its interaction with the nicotinic acetylcholine receptor and phospholemman.

Chibalin AV; Heiny JA; Benziane B; Prokofiev AV; Vasiliev AV; Kravtsova VV; Krivoi II
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(40):34567-34574

Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle.

Kulkarni SS; Karlsson HKR; Szekeres F; Chibalin AV; Krook A; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2011;301(3):E456-E466

Effect of exercise and training on phospholemman phosphorylation in human skeletal muscle.

Benziane B; Widegren U; Pirkmajer S; Henriksson J; Stepto NK; Chibalin AV
Article: EXPERIMENTAL PHYSIOLOGY. 2011;96(9):927-937

Muscle glycogen resynthesis, signalling and metabolic responses following acute exercise in exercise-trained pigs carrying the PRKAG3 mutation.

Essén-Gustavsson B; Granlund A; Benziane B; Jensen-Waern M; Chibalin AV
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2011;301(2):C272-C279

Serum starvation: caveat emptor.

Pirkmajer S; Chibalin AV
Article: DIABETES-METABOLISM RESEARCH AND REVIEWS. 2011;27(3):286-297

Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity.

Mashili FL; Austin RL; Deshmukh AS; Fritz T; Caidahl K; Bergdahl K; Zierath JR; Chibalin AV; Moller DE; Kharitonenkov A; Krook A
Article: PLOS ONE. 2011;6(12):e28294

C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells.

Galuska D; Pirkmajer S; Barrès R; Ekberg K; Wahren J; Chibalin AV
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2010;285(37):28614-28626

The nicotinic acetylcholine receptor and the Na,K-ATPase alpha2 isoform interact to regulate membrane electrogenesis in skeletal muscle.

Heiny JA; Kravtsova VV; Mandel F; Radzyukevich TL; Benziane B; Prokofiev AV; Pedersen SE; Chibalin AV; Krivoi II
Article: JOURNAL OF BIOLOGICAL SYSTEMS. 2010;18(3):687-707

VALIDATION OF THE IN VITRO INCUBATION OF EXTENSOR DIGITORUM LONGUS MUSCLE FROM MICE WITH A MATHEMATICAL MODEL

Sogaard P; Harlen M; Long YC; Szekeres F; Barnes BR; Chibalin AV; Zierath JR
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2010;588(Pt 10):1779-1790

Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor coactivator-1 mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle.

Egan B; Carson BP; Garcia-Roves PM; Chibalin AV; Sarsfield FM; Barron N; McCaffrey N; Moyna NM; Zierath JR; O'Gorman DJ
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2010;109(5):943-949

Spatial insulin signalling in isolated skeletal muscle preparations.

Sogaard P; Szekeres F; Garcia-Roves PM; Larsson D; Chibalin AV; Zierath JR
Article: EXPERIMENTAL PHYSIOLOGY. 2010;95(4):541-549

Effects of exercise on muscle glycogen synthesis signalling and enzyme activities in pigs carrying the PRKAG3 mutation.

Granlund A; Kotova O; Benziane B; Galuska D; Jensen-Waern M; Chibalin AV; Essén-Gustavsson B
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2009;297(6):C1554-C1566

AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.

Benziane B; Björnholm M; Lantier L; Viollet B; Zierath JR; Chibalin AV
Article: JOURNAL OF CELLULAR BIOCHEMISTRY. 2009;107(6):1189-1197

Effects of fibre type and diffusion distance on mouse skeletal muscle glycogen content in vitro.

Sogaard P; Szekeres F; Holmström M; Larsson D; Harlén M; Garcia-Roves P; Chibalin AV
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2009;297(1):E38-E49

Altered expression and insulin-induced trafficking of Na+-K+-ATPase in rat skeletal muscle: effects of high-fat diet and exercise.

Galuska D; Kotova O; Barrès R; Chibalina D; Benziane B; Chibalin AV
Article: CIRCULATION RESEARCH. 2009;104(8):961-968

T cell-mediated inflammation in adipose tissue does not cause insulin resistance in hyperlipidemic mice.

Sultan A; Strodthoff D; Robertson A-K; Paulsson-Berne G; Fauconnier J; Parini P; Rydén M; Thierry-Mieg N; Johansson ME; Chibalin AV; Zierath JR; Arner P; Hansson GK
Article: DIABETES. 2009;58(4):847-854

Kinetics of GLUT4 trafficking in rat and human skeletal muscle.

Karlsson HKR; Chibalin AV; Koistinen HA; Yang J; Koumanov F; Wallberg-Henriksson H; Zierath JR; Holman GD
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2008;295(6):E1427-E1438

Divergent cell signaling after short-term intensified endurance training in human skeletal muscle.

Benziane B; Burton TJ; Scanlan B; Galuska D; Canny BJ; Chibalin AV; Zierath JR; Stepto NK
Article: DIABETES-METABOLISM RESEARCH AND REVIEWS. 2008;24(7):554-562

Globular adiponectin stimulates glucose transport in type 2 diabetic muscle.

Kuoppamaa H; Skrobuk P; Sihvo M; Hiukka A; Chibalin AV; Zierath JR; Koistinen HA
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2008;295(3):E553-E558

Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm.

Benziane B; Chibalin AV
Article: DIABETES. 2008;57(6):1508-1516

Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle.

Bouzakri K; Austin R; Rune A; Lassman ME; Garcia-Roves PM; Berger JP; Krook A; Chibalin AV; Zhang BB; Zierath JR
Article: CELL. 2008;132(3):375-386

Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.

Chibalin AV; Leng Y; Vieira E; Krook A; Björnholm M; Long YC; Kotova O; Zhong Z; Sakane F; Steiler T; Nylén C; Wang J; Laakso M; Topham MK; Gilbert M; Wallberg-Henriksson H; Zierath JR
Article: PATHOPHYSIOLOGY. 2007;14(3-4):153-158

Regulation of the Na,K-ATPase: Special implications for cardiovascular complications of metabolic syndrome.

Chibalin AV
Article: CELLULAR AND MOLECULAR BIOLOGY. 2006;52(8):48-57

Metabolic and signaling events mediated by cardiotonic steroid ouabain in rat skeletal muscle.

Kotova O; Galuska D; Essén-Gustavsson B; Chibalin AV
Article: DIABETOLOGIA. 2006;49(12):2983-2992

Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes.

O'Gorman DJ; Karlsson HKR; McQuaid S; Yousif O; Rahman Y; Gasparro D; Glund S; Chibalin AV; Zierath JR; Nolan JJ
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(31):21690-21697

Neuregulins mediate calcium-induced glucose transport during muscle contraction.

Cantó C; Chibalin AV; Barnes BR; Glund S; Suárez E; Ryder JW; Palacín M; Zierath JR; Zorzano A; Gumà A
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(29):20085-20094

Cardiotonic steroids stimulate glycogen synthesis in human skeletal muscle cells via a Src- and ERK1/2-dependent mechanism.

Kotova O; Al-Khalili L; Talia S; Hooke C; Fedorova OV; Bagrov AY; Chibalin AV
Article: DIABETES. 2006;55(7):2051-2058

AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

Treebak JT; Glund S; Deshmukh A; Klein DK; Long YC; Jensen TE; Jørgensen SB; Viollet B; Andersson L; Neumann D; Wallimann T; Richter EA; Chibalin AV; Zierath JR; Wojtaszewski JFP
Article: DIABETES. 2006;55(6):1776-1782

Exercise-induced phosphorylation of the novel Akt substrates AS160 and filamin A in human skeletal muscle.

Deshmukh A; Coffey VG; Zhong Z; Chibalin AV; Hawley JA; Zierath JR
Article: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2006;17(1):45-52

Differential expression of peroxisomal proliferator activated receptors alpha and delta in skeletal muscle in response to changes in diet and exercise.

Kannisto K; Chibalin A; Glinghammar B; Zierath JR; Hamsten A; Ehrenborg E
Article: FASEB JOURNAL. 2006;20(1):190-192

Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humans.

Coffey VG; Zhong Z; Shield A; Canny BJ; Chibalin AV; Zierath JR; Hawley JA
Article: DIABETES. 2005;54(5):1459-1467

Effects of metformin and rosiglitazone treatment on insulin signaling and glucose uptake in patients with newly diagnosed type 2 diabetes: a randomized controlled study.

Karlsson HKR; Hällsten K; Björnholm M; Tsuchida H; Chibalin AV; Virtanen KA; Heinonen OJ; Lönnqvist F; Nuutila P; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY. 2005;288(2):F334-F344

Insulin potentiates AVP-induced AQP2 expression in cultured renal collecting duct principal cells.

Bustamante M; Hasler U; Kotova O; Chibalin AV; Mordasini D; Rousselot M; Vandewalle A; Martin P-Y; Féraille E
Article: DIABETOLOGIA. 2005;48(1):187-197

C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells.

Zhong Z; Davidescu A; Ehrén I; Ekberg K; Jörnvall H; Wahren J; Chibalin AV
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2004;61(21):2782-2790

C-peptide stimulates Na+, K+-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells.

Zhong Z; Kotova O; Davidescu A; Ehrén I; Ekberg K; Jörnvall H; Wahren J; Chibalin AV
Article: DIABETOLOGIA. 2004;47(Suppl 1):a1-a464

40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004.
Article: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2004;287(1):E1-E7

Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exercise.

Karlsson HKR; Nilsson P-A; Nilsson J; Chibalin AV; Zierath JR; Blomstrand E
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2004;279(24):25211-25218

ERK1/2 mediates insulin stimulation of Na(+),K(+)-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells.

Al-Khalili L; Kotova O; Tsuchida H; Ehrén I; Féraille E; Krook A; Chibalin AV
Article: AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY. 2004;286(6):C1410-C1416

MEF2 activation in differentiated primary human skeletal muscle cultures requires coordinated involvement of parallel pathways.

Al-Khalili L; Chibalin AV; Yu M; Sjödin B; Nylén C; Zierath JR; Krook A
Article: EXPERIMENTAL DIABESITY RESEARCH. 2004;5(1):15-23

Molecular and cellular effects of C-peptide--new perspectives on an old peptide.

Wahren J; Shafqat J; Johansson J; Chibalin A; Ekberg K; Jörnvall H
Article: ENDOCRINOLOGY. 2003;144(12):5259-5267

Effect of hyperglycemia on signal transduction in skeletal muscle from diabetic Goto-Kakizaki rats.

Steiler TL; Galuska D; Leng Y; Chibalin AV; Gilbert M; Zierath JR
Article: DIABETOLOGIA. 2003;46(10):1324-1328

Aberrant p38 mitogen-activated protein kinase signalling in skeletal muscle from Type 2 diabetic patients.

Koistinen HA; Chibalin AV; Zierath JR
Article: CELLULAR AND MOLECULAR LIFE SCIENCES. 2003;60(5):991-998

Insulin action in cultured human skeletal muscle cells during differentiation: assessment of cell surface GLUT4 and GLUT1 content.

Al-Khalili L; Chibalin AV; Kannisto K; Zhang BB; Permert J; Holman GD; Ehrenborg E; Ding VDH; Zierath JR; Krook A
Article: DIABETES. 2003;52(5):1066-1072

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.

Koistinen HA; Galuska D; Chibalin AV; Yang J; Zierath JR; Holman GD; Wallberg-Henriksson H
Article: FEBS LETTERS. 2003;536(1-3):198-202

Na+,K+-ATPase trafficking in skeletal muscle: insulin stimulates translocation of both alpha 1- and alpha 2-subunit isoforms.

Al-Khalili L; Yu M; Chibalin AV
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2003;546(Pt 2):327-335

Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise.

Yu M; Stepto NK; Chibalin AV; Fryer LGD; Carling D; Krook A; Hawley JA; Zierath JR
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2002;295(5):1035-1040

Molecular effects of proinsulin C-peptide.

Johansson J; Ekberg K; Shafqat J; Henriksson M; Chibalin A; Wahren J; Jörnvall H
Article: DIABETOLOGIA. 2002;45(1):56-65

5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice.

Song XM; Fiedler M; Galuska D; Ryder JW; Fernström M; Chibalin AV; Wallberg-Henriksson H; Zierath JR
Article: JOURNAL OF PHYSIOLOGY-LONDON. 2001;536(Pt 1):273-282

Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle.

Yu M; Blomstrand E; Chibalin AV; Krook A; Zierath JR
Article: ENDOCRINOLOGY. 2001;142(8):3474-3482

Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle.

Chibalin AV; Kovalenko MV; Ryder JW; Féraille E; Wallberg-Henriksson H; Zierath JR
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2001;90(1):29-34

Exercise-associated differences in an array of proteins involved in signal transduction and glucose transport.

Yu M; Blomstrand E; Chibalin AV; Wallberg-Henriksson H; Zierath JR; Krook A
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2000;97(1):38-43

Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.

Chibalin AV; Yu M; Ryder JW; Song XM; Galuska D; Krook A; Wallberg-Henriksson H; Zierath JR
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1999;277(6):R1690-R1696

Muscle fiber type specificity in insulin signal transduction.

Song XM; Ryder JW; Kawano Y; Chibalin AV; Krook A; Zierath JR
Article: BIOCHEMICAL JOURNAL. 1999;342 ( Pt 2)(Pt 2):321-328

In vitro analysis of the glucose-transport system in GLUT4-null skeletal muscle.

Ryder JW; Kawano Y; Chibalin AV; Rincón J; Tsao TS; Stenbit AE; Combatsiaris T; Yang J; Holman GD; Charron MJ; Zierath JR
Article: DIABETOLOGIA. 1999;42(Suppl 1):a1-a330

35th Annual Meeting of the European Association for the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999.
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(4):2000-2008

Glucose decreases Na+,K+-ATPase activity in pancreatic beta-cells. An effect mediated via Ca2+-independent phospholipase A2 and protein kinase C-dependent phosphorylation of the alpha-subunit.

Owada S; Larsson O; Arkhammar P; Katz AI; Chibalin AV; Berggren PO; Bertorello AM
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1999;274(4):1920-1927

Dopamine-induced endocytosis of Na+,K+-ATPase is initiated by phosphorylation of Ser-18 in the rat alpha subunit and Is responsible for the decreased activity in epithelial cells.

Chibalin AV; Ogimoto G; Pedemonte CH; Pressley TA; Katz AI; Féraille E; Berggren PO; Bertorello AM
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1999;276(1):L20-L27

Isoproterenol increases Na+-K+-ATPase activity by membrane insertion of alpha-subunits in lung alveolar cells.

Bertorello AM; Ridge KM; Chibalin AV; Katz AI; Sznajder JI
Article: HUMAN GENETICS. 1998;103(4):529-531

Functional characterisation of mutations in the ligand-binding domain of the androgen receptor gene in patients with androgen insensitivity syndrome.

Lundberg Giwercman Y; Nikoshkov A; Lindsten K; Byström B; Pousette A; Chibalin AV; Arvidsson S; Tiulpakov A; Semitcheva TV; Peterkova V; Hagenfeldt K; Ritzén EM; Wedell A
Article: FASEB JOURNAL. 1998;12(13):1379-1389

Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle.

Widegren U; Jiang XJ; Krook A; Chibalin AV; Björnholm M; Tally M; Roth RA; Henriksson J; Wallberg-henriksson H; Zierath JR
Article: JOURNAL OF PHYSIOLOGY-LONDON. 1998;511 ( Pt 1)(Pt 1):235-243

Protein kinase A induces recruitment of active Na+,K+-ATPase units to the plasma membrane of rat proximal convoluted tubule cells.

Carranza ML; Rousselot M; Chibalin AV; Bertorello AM; Favre H; Féraille E
Article: MOLECULAR BIOLOGY OF THE CELL. 1998;9(5):1209-1220

Phosphatidylinositol 3-kinase-mediated endocytosis of renal Na+, K+-ATPase alpha subunit in response to dopamine.

Chibalin AV; Zierath JR; Katz AI; Berggren PO; Bertorello AM
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 1998;273(15):8814-8819

Phosphorylation of the catalyic alpha-subunit constitutes a triggering signal for Na+,K+-ATPase endocytosis.

Chibalin AV; Pedemonte CH; Katz AI; Féraille E; Berggren PO; Bertorello AM
Article: AMERICAN JOURNAL OF PHYSIOLOGY. 1997;273(5):C1458-C1465

Receptor-mediated inhibition of renal Na(+)-K(+)-ATPase is associated with endocytosis of its alpha- and beta-subunits.

Chibalin AV; Katz AI; Berggren PO; Bertorello AM
Article: SCIENCE. 1996;271(5250):813-815

PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells.

Eliasson L; Renström E; Ammälä C; Berggren PO; Bertorello AM; Bokvist K; Chibalin A; Deeney JT; Flatt PR; Gäbel J; Gromada J; Larsson O; Lindström P; Rhodes CJ; Rorsman P
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Review: JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY. 2021;42(1):77-97

The role of AMPK in regulation of Na+,K+-ATPase in skeletal muscle: does the gauge always plug the sink?

Pirkmajer S; Petrič M; Chibalin AV
Review: PERIODICUM BIOLOGORUM. 2020;121(3-4):129-145

ATIC as a link between antirheumatic drugs and regulation of energy metabolism in skeletal muscle

Dolinar K; Chibalin AV; Pirkmajer S
Review: CELLULAR MECHANOTRANSDUCTION MECHANISMS IN CARDIOVASCULAR AND FIBROTIC DISEASES. 2019;83:315-351

Hormonal regulation of Na+-K+-ATPase from the evolutionary perspective.

Pirkmajer S; Chibalin AV
Review: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2016;311(1):E1-E31

Na,K-ATPase regulation in skeletal muscle.

Pirkmajer S; Chibalin AV
Editorial comment: ACTA PHYSIOLOGICA. 2016;216(4):386-391

NO turns on Na,K-ATPase in skeletal muscle.

Pirkmajer S; Chibalin AV
Published paper: DIABETES-METABOLISM RESEARCH AND REVIEWS. 2014;30(2):124-131

Enhanced insulin action following subcutaneous co-administration of insulin and C-peptide in rats.

Kubota M; Sato Y; Khookhor O; Ekberg K; Chibalin AV; Wahren J
Letter: JOURNAL OF APPLIED PHYSIOLOGY. 2012;112(12):2125

ASSESSMENT OF SARCOLEMMAL NA⁺- K⁺- ATPASE ACTIVITY: TOWARD A REFERENCE METHOD

Chibalin AV; Pirkmajer S
Letter: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. 2008;295(3):E729

Regulatory role of translocation of Na⁺-K⁺ pumps in skeletal muscle:: hypothesis or reality?: Reply

Chibalin AV; Benziane B
Published paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 2003;986:449-452

Phosphorylation of the Na+,K+-ATPase in skeletal muscle: potential mechanism for changes in pump cell-surface abundance and activity.

Al-Khalili L; Krook A; Chibalin AV
Meeting abstract: ATHEROSCLEROSIS SUPPLEMENTS. 2003;4(2):219

Effects of diet and exercise on the regulation of PPARα, δ and γ expression in rat skeletal muscle and visceral adipose tissue

Kannisto K; Chibalin A; Zierath JR; Hamsten A; Ehrenborg E
Published paper: ACTA PHYSIOLOGICA. 2001;171(3):249-257

Intracellular mechanisms underlying increases in glucose uptake in response to insulin or exercise in skeletal muscle.

Ryder JW; Chibalin AV; Zierath JR
Published paper: CLINICAL AND EXPERIMENTAL HYPERTENSION. 1997;19(1-2):73-86

Short-term vs. sustained inhibition of proximal tubule Na,K-ATPase activity by dopamine: cellular mechanisms.

Pinto-do-O PC; Chibalin AV; Katz AI; Soares-da-Silva P; Bertorello AM

Anställningar

Senior Forskningsspecialist, Molekylär medicin och kirurgi, Karolinska Institutet, 2022-

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Docent, Cellfysiologi, Karolinska Institutet, 2003

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