Alamdar Hussain

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CYTOTHERAPY. 2023;25(7):763-772

Challenges in αCD38-chimeric antigen receptor (CAR)-expressing natural killer (NK) cell-based immunotherapy in multiple myeloma: Harnessing the CD38dim phenotype of cytokine-stimulated NK cells as a strategy to prevent fratricide.

Karvouni M; Vidal-Manrique M; Susek KH; Hussain A; Gilljam M; Zhang Y; Gray JD; Lund J; Kaufmann G; Ljunggren H-G; Ji H; Lundqvist A; Wagner AK; Guo W; Alici E
Journal article: CYTOTHERAPY. 2023;25(6):s13-s14

13 Tissue Engineering: GENERATION OF UNIVERSAL CELLULAR GRAFTS UTILIZING SIGNALING-DEFICIENT MEMBRANE-BOUND CD45 ENGAGERS

Hussain A; Mohammad DK; Karvouni M; Hållstrand C; Gilljam M; Wagner AK; Ljunggren H; Alici E
Article: CANCER IMMUNOLOGY IMMUNOTHERAPY. 2023;72(5):1153-1167

Generation of NK cells with chimeric-switch receptors to overcome PD1-mediated inhibition in cancer immunotherapy.

Susek KH; Schwietzer YA; Karvouni M; Gilljam M; Keszei M; Hussain A; Lund J; Kashif M; Lundqvist A; Ljunggren H-G; Nahi H; Wagner AK; Alici E
Article: CURRENT ISSUES IN MOLECULAR BIOLOGY. 2022;44(9):3859-3871

Assessment of T Cell Receptor Complex Expression Kinetics in Natural Killer Cells.

Rasul KH; Hussain A; Reilly H; Karvouni M; Dahlberg CIM; Al-Attar MS; Wagner AK; Alici E; Mohammad DK
Journal article: HEMASPHERE. 2022;6(Suppl):1318-1319

P1435: PRECLINICAL EVALUATION OF ZILOVERTAMAB‐BASED ANTI‐ROR1 CHIMERIC ANTIGEN RECEPTORS IN NK AND T CELLS

Meinke S; Kadri N; Bi S; Bostancioglu B; Markey C; Breitmeyer JB; Hussain A; Krishnan R; Kaufmann GF; Alici E
Journal article: INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES. 2021;180:739-752

Role of receptor tyrosine kinases mediated signal transduction pathways in tumor growth and angiogenesis-New insight and futuristic vision.

Huang XL; Khan MI; Wang J; Ali R; Ali SW; Zahra Q-U; Kazmi A; Lolai A; Huang YL; Hussain A; Bilal M; Li F; Qiu B
Article: EUROPEAN JOURNAL OF HAEMATOLOGY. 2020;105(2):196-202

Impact of performance status on overall survival in patients with relapsed and/or refractory multiple myeloma: Real-life outcomes of daratumumab treatment.

Afram G; Gran C; Borg Bruchfeld J; Wagner AK; Hussain A; Alici E; Nahi H
Article: GENETICS AND MOLECULAR BIOLOGY. 2019;42(1):40-47

Increased expression levels of Syntaxin 1A and Synaptobrevin 2/Vesicle-Associated Membrane Protein-2 are associated with the progression of bladder cancer.

Raja SA; Abbas S; Shah STA; Tariq A; Bibi N; Yousuf A; Khawaja A; Nawaz M; Mehmood A; Khan MJ; Hussain A
Article: GENETICS AND MOLECULAR BIOLOGY. 2018;41(3):570-577

Decreased serum PON1 arylesterase activity in familial hypercholesterolemia patients with a mutated LDLR gene.

Idrees M; Siddiq AR; Ajmal M; Akram M; Khalid RR; Hussain A; Qamar R; Bokhari H
Article: LANCET INFECTIOUS DISEASES. 2018;18(6):675-683

Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study.

Zignol M; Cabibbe AM; Dean AS; Glaziou P; Alikhanova N; Ama C; Andres S; Barbova A; Borbe-Reyes A; Chin DP; Cirillo DM; Colvin C; Dadu A; Dreyer A; Driesen M; Gilpin C; Hasan R; Hasan Z; Hoffner S; Hussain A; Ismail N; Kamal SMM; Khanzada FM; Kimerling M; Kohl TA; Mansjö M; Miotto P; Mukadi YD; Mvusi L; Niemann S; Omar SV; Rigouts L; Schito M; Sela I; Seyfaddinova M; Skenders G; Skrahina A; Tahseen S; Wells WA; Zhurilo A; Weyer K; Floyd K; Raviglione MC
Article: TOXICOLOGY MECHANISMS AND METHODS. 2018;28(1):62-68

In silico and in vitro evaluation of two novel oximes (K378 and K727) in comparison to K-27 and pralidoxime against paraoxon-ethyl intoxication.

Arshad M; Fatmi MQ; Musilek K; Hussain A; Kuca K; Petroianu G; Kalasz H; Nurulain SM
Article: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. 2017;58(9):3481-3487

TNF-α Genetic Predisposition and Higher Expression of Inflammatory Pathway Components in Keratoconus.

Arbab M; Tahir S; Niazi MK; Ishaq M; Hussain A; Siddique PM; Saeed S; Khan WA; Qamar R; Butt AM; Azam M
Article: ENVIRONMENTAL GEOCHEMISTRY AND HEALTH. 2015;37(3):515-527

Toxic metals signature in the human seminal plasma of Pakistani population and their potential role in male infertility.

Zafar A; Eqani SAMAS; Bostan N; Cincinelli A; Tahir F; Shah STA; Hussain A; Alamdar A; Huang Q; Peng S; Shen H
Article: PLOS ONE. 2015;10(3):e0119806

Homozygosity mapping and targeted sanger sequencing reveal genetic defects underlying inherited retinal disease in families from pakistan.

Maria M; Ajmal M; Azam M; Waheed NK; Siddiqui SN; Mustafa B; Ayub H; Ali L; Ahmad S; Micheal S; Hussain A; Shah STA; Ali SHB; Ahmed W; Khan YM; den Hollander AI; Haer-Wigman L; Collin RWJ; Khan MI; Qamar R; Cremers FPM
Article: ENVIRONMENTAL GEOCHEMISTRY AND HEALTH. 2014;36(3):375-384

Cattle egrets as a biosentinels of persistent organic pollutants exposure.

Khan M; Mohammad A; Ahad K; Katsoyiannis A; Malik SA; Abdullaha M; Rashid A; Fasola M; Hussain A; Bokhari H; Eqani SAMAS
Article: PLOS ONE. 2014;9(6):e100146

Genetic spectrum of autosomal recessive non-syndromic hearing loss in Pakistani families.

Shafique S; Siddiqi S; Schraders M; Oostrik J; Ayub H; Bilal A; Ajmal M; Seco CZ; Strom TM; Mansoor A; Mazhar K; Shah STA; Hussain A; Azam M; Kremer H; Qamar R
Article: MOLECULAR AND CELLULAR BIOLOGY. 2013;33(16):3214-3226

Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells.

Mohammad DK; Nore BF; Hussain A; Gustafsson MO; Mohamed AJ; Smith CIE
Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2013;288(10):7338-7350

Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.

Hussain A; Mohammad DK; Gustafsson MO; Uslu M; Hamasy A; Nore BF; Mohamed AJ; Smith CIE
Article: MOLECULAR AND CELLULAR BIOLOGY. 2012;32(13):2440-2453

Regulation of nucleocytoplasmic shuttling of Bruton's tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).

Gustafsson MO; Hussain A; Mohammad DK; Mohamed AJ; Nguyen V; Metalnikov P; Colwill K; Pawson T; Smith CIE; Nore BF
Article: PLOS ONE. 2012;7(5):e36804

Ischemia-reperfusion injury and pregnancy initiate time-dependent and robust signs of up-regulation of cardiac progenitor cells.

Genead R; Fischer H; Hussain A; Jaksch M; Andersson AB; Ljung K; Bulatovic I; Franco-Cereceda A; Elsheikh E; Corbascio M; Smith CIE; Sylvén C; Grinnemo K-H
Article: OPHTHALMOLOGY. 2011;118(7):1444-1448

CLRN1 mutations cause nonsyndromic retinitis pigmentosa.

Khan MI; Kersten FFJ; Azam M; Collin RWJ; Hussain A; Shah ST-A; Keunen JEE; Kremer H; Cremers FPM; Qamar R; den Hollander AI
Article: MOLECULAR VISION. 2010;16:774-781

Novel CNGA3 and CNGB3 mutations in two Pakistani families with achromatopsia.

Azam M; Collin RWJ; Shah STA; Shah AA; Khan MI; Hussain A; Sadeque A; Strom TM; Thiadens AAHJ; Roosing S; den Hollander AI; Cremers FPM; Qamar R
Article: BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2009;390(3):892-896

Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein.

Hussain A; Faryal R; Nore BF; Mohamed AJ; Smith CIE
Article: MOLECULAR VISION. 2009;15:2526-2534

A homozygous p.Glu150Lys mutation in the opsin gene of two Pakistani families with autosomal recessive retinitis pigmentosa.

Azam M; Khan MI; Gal A; Hussain A; Shah STA; Khan MS; Sadeque A; Bokhari H; Collin RWJ; Orth U; van Genderen MM; den Hollander AI; Cremers FPM; Qamar R
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Conference publication: CYTOTHERAPY. 2023;25(6):S13-S14

GENERATION OF UNIVERSAL CELLULAR GRAFTS UTILIZING SIGNALING-DEFICIENT MEMBRANE-BOUND CD45 ENGAGERS

Hussain A; Mohammad DK; Karvouni M; Hallstrand C; Gilljam M; Wagner AK; Ljunggren H; Alici E
Conference publication: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2017;86(4):348

Optimized genetic modification of primary human NK cells

Wagner AK; Chrobok M; Hussain A; Gilljam M; Dahlberg CIM; Sutlu T; Duru AD; Nahi H; Lundqvist A; Ljunggren H-G; Alici E
Letter: HUMAN MUTATION. 2014;35(1):147-148

Comprehensive registration of DNA sequence variants associated with inherited retinal diseases in Leiden Open Variation Databases.

Cremers FPM; den Dunnen JT; Ajmal M; Hussain A; Preising MN; Daiger SP; Qamar R
Letter: ARCHIVES OF OPHTHALMOLOGY. 2011;129(10):1377-1378

Identification of novel mutations in Pakistani families with autosomal recessive retinitis pigmentosa.

Azam M; Collin RWJ; Malik A; Khan MI; Shah STA; Shah AA; Hussain A; Sadeque A; Arimadyo K; Ajmal M; Azam A; Qureshi N; Bokhari H; Strom TM; Cremers FPM; Qamar R; den Hollander AI
Review: FEBS JOURNAL. 2011;278(12):2001-2010

TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.

Hussain A; Yu L; Faryal R; Mohammad DK; Mohamed AJ; Smith CIE

Anställningar

Forskningsspecialist, Medicin, Huddinge, Karolinska Institutet, 2022-

Examina och utbildning

Medicine Doktorsexamen, Institutionen för laboratoriemedicin, Karolinska Institutet, 2013

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