Akira Kaneko

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About me

Based on achievements as malariologist in malaria elimination on islands in Vanuatu from 1987 to 1994, I have conducted research on malaria epidemiology, chemotherapy and elimination in Vanuatu, Papua New Gunea, Indonesia, Cambodia, Malawi, Zanzibar, Ghana, and recently the Lake Victoria area in Kenya. Since 2011, I am Professor of Global Health and leader of the Island Malaria Group at the Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet.

Articles

Article: MALARIA JOURNAL. 2022;21(1):252

Potential application of the haematology analyser XN-31 prototype for field malaria surveillance in Kenya.

Kagaya W; Takehara I; Kurihara K; Maina M; Chan CW; Okomo G; Kongere J; Gitaka J; Kaneko A
Article: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY. 2022;12:953585

Seroepidemiological surveillance, community perceptions and associated risk factors of malaria exposure among forest-goers in Northeastern Thailand.

Rahim MAFA; Chuangchaiya S; Chanpum P; Palawong L; Kantee P; Dian ND; Lubis IND; Divis PCS; Kaneko A; Tetteh KKA; Idris ZM
Article: SCIENTIFIC REPORTS. 2021;11(1):19809

Characterizing the genomic variation and population dynamics of Plasmodium falciparum malaria parasites in and around Lake Victoria, Kenya.

Osborne A; Manko E; Takeda M; Kaneko A; Kagaya W; Chan C; Ngara M; Kongere J; Kita K; Campino S; Kaneko O; Gitaka J; Clark TG
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2021;33(3):e23500

Relationships between mental health and diet during pregnancy and birth outcomes in a lower-middle income country: "Healthy mothers, healthy communities" study in Vanuatu.

Therrien A-S; Buffa G; Roome AB; Standard E; Pomer A; Obed J; Taleo G; Tarivonda L; Chan CW; Kaneko A; Olszowy KM; Dancause KN
Article: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH. 2020;17(19):E7351-7351

Relationships between Prenatal Distress and Infant Body Mass Index in the First Year of Life in a Lower-Middle Income Country.

Therrien A-S; Buffa G; Roome AB; Standard E; Pomer A; Obed J; Taleo G; Tarivonda L; W Chan C; Kaneko A; Olszowy KM; Dancause KN
Article: DRUG METABOLISM AND PHARMACOKINETICS. 2020;35(1):89-101

CYP2D6 genotyping analysis and functional characterization of novel allelic variants in a Ni-Vanuatu and Kenyan population by assessing dextromethorphan O-demethylation activity.

Gutiérrez Rico EM; Kikuchi A; Saito T; Kumondai M; Hishinuma E; Kaneko A; Chan CW; Gitaka J; Nakayoshi T; Oda A; Saito S; Hirasawa N; Hiratsuka M
Article: SCIENTIFIC REPORTS. 2019;9(1):19060

Malaria resurgence after significant reduction by mass drug administration on Ngodhe Island, Kenya.

Kagaya W; Gitaka J; Chan CW; Kongere J; Md Idris Z; Deng C; Kaneko A
Article: ARCHIVES OF WOMENS MENTAL HEALTH. 2019;22(6):825-829

Psychosocial distress among women following a natural disaster in a low- to middle-income country: "healthy mothers, healthy communities" study in Vanuatu.

Pomer A; Buffa G; Ayoub M-B; Taleo F; Sizemore JH; Tokon A; Chan CW; Kaneko A; Obed J; Iaruel J; Taleo G; Tarivonda L; Dancause KN
Article: PUBLIC HEALTH NUTRITION. 2019;22(9):1533-1544

Using multiple correspondence analysis to identify behaviour patterns associated with overweight and obesity in Vanuatu adults.

van Horn A; Weitz CA; Olszowy KM; Dancause KN; Sun C; Pomer A; Silverman H; Lee G; Tarivonda L; Chan CW; Kaneko A; Lum JK; Garruto RM
Article: AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY. 2018;167(4):760-776

Coming to grips with economic development: Variation in adult hand grip strength during health transition in Vanuatu.

Olszowy KM; Little MA; Lee G; Pomer A; Dancause KN; Sun C; Silverman H; Chan CW; Tarivonda L; Kaneko A; Weitz C; Koji Lum J; Garruto RM
Article: SCIENTIFIC REPORTS. 2018;8(1):5565

Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea.

Mita T; Hombhanje F; Takahashi N; Sekihara M; Yamauchi M; Tsukahara T; Kaneko A; Endo H; Ohashi J
Article: ANNALS OF HUMAN BIOLOGY. 2018;45(3):220-228

Relationships between psychosocial distress and diet during pregnancy and infant birthweight in a lower-middle income country: 'healthy mothers, healthy communities' study in Vanuatu.

Pomer A; Buffa G; Taleo F; Sizemore JH; Tokon A; Taleo G; Tarivonda L; Chan CW; Kaneko A; Dancause KN
Article: MALARIA JOURNAL. 2018;17(1):72

Improvement of malaria diagnostic system based on acridine orange staining.

Kimura M; Teramoto I; Chan CW; Idris ZM; Kongere J; Kagaya W; Kawamoto F; Asada R; Isozumi R; Kaneko A
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2017;29(5)

Secular change in adult stature associated with modernization in Vanuatu.

Olszowy KM; Sun C; Silverman H; Pomer A; Dancause KN; Chan CW; Lee G; Tarivonda L; Kaneko A; Weitz C; Koji Lum J; Garruto RM
Article: SCIENTIFIC REPORTS. 2017;7(1):9123

Naturally acquired antibody response to Plasmodium falciparum describes heterogeneity in transmission on islands in Lake Victoria.

Idris ZM; Chan CW; Kongere J; Hall T; Logedi J; Gitaka J; Drakeley C; Kaneko A
Article: PARASITES & VECTORS. 2017;10(1):204

Serological measures to assess the efficacy of malaria control programme on Ambae Island, Vanuatu.

Idris ZM; Chan CW; Mohammed M; Kalkoa M; Taleo G; Junker K; Arcà B; Drakeley C; Kaneko A
Article: MALARIA JOURNAL. 2017;16(1):141

Challenges for achieving safe and effective radical cure of Plasmodium vivax: a round table discussion of the APMEN Vivax Working Group.

Thriemer K; Ley B; Bobogare A; Dysoley L; Alam MS; Pasaribu AP; Sattabongkot J; Jambert E; Domingo GJ; Commons R; Auburn S; Marfurt J; Devine A; Aktaruzzaman MM; Sohel N; Namgay R; Drukpa T; Sharma SN; Sarawati E; Samad I; Theodora M; Nambanya S; Ounekham S; Mudin RNB; Da Thakur G; Makita LS; Deray R; Lee S-E; Boaz L; Danansuriya MN; Mudiyanselage SD; Chinanonwait N; Kitchakarn S; Nausien J; Naket E; Duc TN; Do Manh H; Hong YS; Cheng Q; Richards JS; Kusriastuti R; Satyagraha A; Noviyanti R; Ding XC; Khan WA; Swe Phru C; Guoding Z; Qi G; Kaneko A; Miotto O; Nguitragool W; Roobsoong W; Battle K; Howes RE; Roca-Feltrer A; Duparc S; Bhowmick IP; Kenangalem E; Bibit J-A; Barry A; Sintasath D; Abeyasinghe R; Sibley CH; McCarthy J; von Seidlein L; Baird JK; Price RN
Article: ASIA-PACIFIC JOURNAL OF PUBLIC HEALTH. 2017;29(3):180-188

Rolling Tobacco in Banana Leaves, Newspaper, or Copybook Paper Associated With Significant Reduction in Lung Function in Vanuatu.

Weitz CA; Olszowy KM; Dancause KN; Sun C; Pomer A; Silverman H; Lee G; Tarivonda L; Chan CW; Kaneko A; Lum JK; Garruto RM
Article: MALARIA JOURNAL. 2017;16(1):98

Selections, frameshift mutations, and copy number variation detected on the surf 4.1 gene in the western Kenyan Plasmodium falciparum population.

Gitaka JN; Takeda M; Kimura M; Idris ZM; Chan CW; Kongere J; Yahata K; Muregi FW; Ichinose Y; Kaneko A; Kaneko O
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2017;29(2)

Ownership of consumer electronics is associated with measures of adiposity during health transition in Vanuatu.

Sun C; Pomer A; Dancause KN; Chan CW; Olszowy KM; Silverman H; Lee G; Tarivonda L; Taleo G; Regenvanu R; Kaneko A; Weitz CA; Garruto RM; Lum JK
Article: EPIDEMIOLOGY AND INFECTION. 2017;145(1):41-45

Surveillance for malaria outbreak on malaria-eliminating islands in Tafea Province, Vanuatu after Tropical Cyclone Pam in 2015.

Chan CW; Iata H; Yaviong J; Kalkoa M; Yamar S; Taleo G; Isozumi R; Fukui M; Aoyama F; Pomer A; Dancause KN; Kaneko A
Article: SCIENTIFIC REPORTS. 2016;6:36958

High and Heterogeneous Prevalence of Asymptomatic and Sub-microscopic Malaria Infections on Islands in Lake Victoria, Kenya.

Idris ZM; Chan CW; Kongere J; Gitaka J; Logedi J; Omar A; Obonyo C; Machini BK; Isozumi R; Teramoto I; Kimura M; Kaneko A
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2016;95(5):1077-1085

Genetic Diversity and Population Structure of Plasmodium falciparum in Lake Victoria Islands, A Region of Intense Transmission.

Mulenge FM; Hunja CW; Magiri E; Culleton R; Kaneko A; Aman RA
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2016;60(6):3340-3347

Little Polymorphism at the K13 Propeller Locus in Worldwide Plasmodium falciparum Populations Prior to the Introduction of Artemisinin Combination Therapies.

Mita T; Culleton R; Takahashi N; Nakamura M; Tsukahara T; Hunja CW; Win ZZ; Htike WW; Marma AS; Dysoley L; Ndounga M; Dzodzomenyo M; Akhwale WS; Kobayashi J; Uemura H; Kaneko A; Hombhanje F; Ferreira MU; Björkman A; Endo H; Ohashi J
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2015;27(6):832-844

Impact of modernization on adult body composition on five islands of varying economic development in Vanuatu.

Olszowy KM; Pomer A; Dancause KN; Sun C; Silverman H; Lee G; Chan CW; Tarivonda L; Regenvanu R; Kaneko A; Weitz CA; Lum JK; Garruto RM
Article: MALARIA JOURNAL. 2015;14:291

A prescription for sustaining community engagement in malaria elimination on Aneityum Island, Vanuatu: an application of Health Empowerment Theory.

Watanabe N; Kaneko A; Yamar S; Taleo G; Tanihata T; Lum JK; Larson PS; Shearer NBC
Article: PARASITOLOGY INTERNATIONAL. 2015;64(3):304-308

Improved detection of malaria cases in island settings of Vanuatu and Kenya by PCR that targets the Plasmodium mitochondrial cytochrome c oxidase III (cox3) gene.

Isozumi R; Fukui M; Kaneko A; Chan CW; Kawamoto F; Kimura M
Article: VACCINE. 2015;33(16):1901-1908

Plasmodium vivax gametocyte proteins, Pvs48/45 and Pvs47, induce transmission-reducing antibodies by DNA immunization.

Tachibana M; Suwanabun N; Kaneko O; Iriko H; Otsuki H; Sattabongkot J; Kaneko A; Herrera S; Torii M; Tsuboi T
Article: EMERGING INFECTIOUS DISEASES. 2015;21(3):490-492

Novel mutations in K13 propeller gene of artemisinin-resistant Plasmodium falciparum.

Isozumi R; Uemura H; Kimata I; Ichinose Y; Logedi J; Omar AH; Kaneko A
Article: PLOS ONE. 2015;10(3):e0119475

Plasmodium vivax and Plasmodium falciparum at the crossroads of exchange among islands in Vanuatu: implications for malaria elimination strategies.

Chan CW; Sakihama N; Tachibana S-I; Idris ZM; Lum JK; Tanabe K; Kaneko A
Article: MALARIA JOURNAL. 2014;13:441

Determinants of the use of insecticide-treated bed nets on islands of pre- and post-malaria elimination: an application of the health belief model in Vanuatu.

Watanabe N; Kaneko A; Yamar S; Leodoro H; Taleo G; Tanihata T; Lum JK; Larson PS
Article: INFECTION GENETICS AND EVOLUTION. 2014;24:111-115

Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.

Jovel IT; Ferreira PE; Veiga MI; Malmberg M; Mårtensson A; Kaneko A; Zakeri S; Murillo C; Nosten F; Björkman A; Ursing J
Article: INFECTION AND IMMUNITY. 2014;82(1):243-252

Characteristic age distribution of Plasmodium vivax infections after malaria elimination on Aneityum Island, Vanuatu.

Kaneko A; Chaves LF; Taleo G; Kalkoa M; Isozumi R; Wickremasinghe R; Perlmann H; Takeo S; Tsuboi T; Tachibana S-I; Kimura M; Björkman A; Troye-Blomberg M; Tanabe K; Drakeley C
Article: PARASITOLOGY. 2013;140(5):580-586

When they don't bite, we smell money: understanding malaria bednet misuse.

Honjo K; Chaves LF; Satake A; Kaneko A; Minakawa N
Article: DRUG METABOLISM AND PHARMACOKINETICS. 2013;28(6):519-521

Frequency of the functionally relevant aryl hydrocarbon receptor repressor (AhRR) Pro185Ala SNP in Papua New Guinea.

Cavaco I; Hombhanje FW; Gil JP; Kaneko A
Article: OBESITY. 2013;21(1):E98-E104

Behavioral risk factors for obesity during health transition in Vanuatu, South Pacific.

Dancause KN; Vilar M; Wilson M; Soloway LE; DeHuff C; Chan C; Tarivonda L; Regenvanu R; Kaneko A; Lum JK; Garruto RM
Article: MOLECULAR BIOLOGY AND EVOLUTION. 2012;29(9):2095-2099

The Plasmodium apicoplast genome: conserved structure and close relationship of P. ovale to rodent malaria parasites.

Arisue N; Hashimoto T; Mitsui H; Palacpac NMQ; Kaneko A; Kawai S; Hasegawa M; Tanabe K; Horii T
Article: MALARIA JOURNAL. 2012;11:92

Large-scale survey for novel genotypes of Plasmodium falciparum chloroquine-resistance gene pfcrt.

Takahashi N; Tanabe K; Tsukahara T; Dzodzomenyo M; Dysoley L; Khamlome B; Sattabongkot J; Nakamura M; Sakurai M; Kobayashi J; Kaneko A; Endo H; Hombhanje F; Tsuboi T; Mita T
Article: VACCINE. 2012;30(9):1583-1593

Geographic differentiation of polymorphism in the Plasmodium falciparum malaria vaccine candidate gene SERA5.

Tanabe K; Arisue N; Palacpac NMQ; Yagi M; Tougan T; Honma H; Ferreira MU; Färnert A; Björkman A; Kaneko A; Nakamura M; Hirayama K; Mita T; Horii T
Article: PUBLIC HEALTH NUTRITION. 2012;15(1):158-166

Patterns of childhood and adolescent overweight and obesity during health transition in Vanuatu.

Dancause KN; Vilar M; Chan C; DeHuff C; Wilson M; Soloway LE; Tarivonda L; Regenvanu R; Kaneko A; Garruto RM; Lum JK
Article: VACCINE. 2011;29(26):4308-4315

Worldwide sequence conservation of transmission-blocking vaccine candidate Pvs230 in Plasmodium vivax.

Doi M; Tanabe K; Tachibana S-I; Hamai M; Tachibana M; Mita T; Yagi M; Zeyrek FY; Ferreira MU; Ohmae H; Kaneko A; Randrianarivelojosia M; Sattabongkot J; Cao Y-M; Horii T; Torii M; Tsuboi T
Article: AMERICAN JOURNAL OF HUMAN BIOLOGY. 2011;23(3):366-376

Behavioral changes associated with economic development in the South Pacific: health transition in Vanuatu.

Dancause KN; Dehuff C; Soloway LE; Vilar M; Chan C; Wilson M; Tarivonda L; Regenvanu R; Kaneko A; Garruto RM; Lum JK
Article: TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE. 2011;105(4):226-231

Spleen rates in children: an old and new surveillance tool for malaria elimination initiatives in island settings.

Chaves LF; Taleo G; Kalkoa M; Kaneko A
Article: PLOS ONE. 2011;6(3):e17775

Clues to evolution of the SERA multigene family in 18 Plasmodium species.

Arisue N; Kawai S; Hirai M; Palacpac NMQ; Jia M; Kaneko A; Tanabe K; Horii T
Article: PLOS ONE. 2011;6(12):e29137

The origins of African Plasmodium vivax; insights from mitochondrial genome sequencing.

Culleton R; Coban C; Zeyrek FY; Cravo P; Kaneko A; Randrianarivelojosia M; Andrianaranjaka V; Kano S; Farnert A; Arez AP; Sharp PM; Carter R; Tanabe K
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2011;55(1):94-100

Spontaneous mutations in the Plasmodium falciparum sarcoplasmic/ endoplasmic reticulum Ca2+-ATPase (PfATP6) gene among geographically widespread parasite populations unexposed to artemisinin-based combination therapies.

Tanabe K; Zakeri S; Palacpac NMQ; Afsharpad M; Randrianarivelojosia M; Kaneko A; Marma ASP; Horii T; Mita T
Article: PLOS ONE. 2011;6(9):e23875

PfMDR1: mechanisms of transport modulation by functional polymorphisms.

Ferreira PE; Holmgren G; Veiga MI; Uhlén P; Kaneko A; Gil JP
Article: CURRENT BIOLOGY. 2010;20(14):1283-1289

Plasmodium falciparum accompanied the human expansion out of Africa.

Tanabe K; Mita T; Jombart T; Eriksson A; Horibe S; Palacpac N; Ranford-Cartwright L; Sawai H; Sakihama N; Ohmae H; Nakamura M; Ferreira MU; Escalante AA; Prugnolle F; Björkman A; Färnert A; Kaneko A; Horii T; Manica A; Kishino H; Balloux F
Article: JOURNAL OF INFECTIOUS DISEASES. 2009;200(9):1456-1464

Plasmodium falciparum multidrug resistance protein 1 and artemisinin-based combination therapy in Africa.

Dahlström S; Ferreira PE; Veiga MI; Sedighi N; Wiklund L; Mårtensson A; Färnert A; Sisowath C; Osório L; Darban H; Andersson B; Kaneko A; Conseil G; Björkman A; Gil JP
Article: ECOLOGY. 2009;90(9):2414-2425

Random, top-down, or bottom-up coexistence of parasites: malaria population dynamics in multi-parasitic settings.

Chaves LF; Kaneko A; Pascual M
Article: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY. 2009;63(2):252-255

Indigenous evolution of Plasmodium falciparum pyrimethamine resistance multiple times in Africa.

Mita T; Tanabe K; Takahashi N; Culleton R; Ndounga M; Dzodzomenyo M; Akhwale WS; Kaneko A; Kobayakawa T
Article: MALARIA JOURNAL. 2008;7:174

Failure to detect Plasmodium vivax in West and Central Africa by PCR species typing.

Culleton RL; Mita T; Ndounga M; Unger H; Cravo PVL; Paganotti GM; Takahashi N; Kaneko A; Eto H; Tinto H; Karema C; D'Alessandro U; do Rosário V; Kobayakawa T; Ntoumi F; Carter R; Tanabe K
Article: MALARIA JOURNAL. 2008;7:100

Malaria transmission pattern resilience to climatic variability is mediated by insecticide-treated nets.

Chaves LF; Kaneko A; Taleo G; Pascual M; Wilson ML
Article: ACTA TROPICA. 2008;106(3):207-212

Changing patterns of forest malaria among the mobile adult male population in Chumkiri District, Cambodia.

Dysoley L; Kaneko A; Eto H; Mita T; Socheat D; Börkman A; Kobayakawa T
Article: INFECTION GENETICS AND EVOLUTION. 2008;8(3):340-345

Diversity of the sarco/endoplasmic reticulum Ca(2+)-ATPase orthologue of Plasmodium falciparum (PfATP6).

Dahlström S; Veiga MI; Ferreira P; Mårtensson A; Kaneko A; Andersson B; Björkman A; Gil JP
Article: JOURNAL OF HUMAN GENETICS. 2008;53(8):698-708

Reconstructing the origin of the Lapita Cultural Complex: mtDNA analyses of East Sepik Province, PNG.

Vilar MG; Kaneko A; Hombhanje FW; Tsukahara T; Hwaihwanje I; Lum JK
Article: PLOS MEDICINE. 2007;4(11):e309-1790

Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar.

Bhattarai A; Ali AS; Kachur SP; Mårtensson A; Abbas AK; Khatib R; Al-Mafazy A-W; Ramsan M; Rotllant G; Gerstenmaier JF; Molteni F; Abdulla S; Montgomery SM; Kaneko A; Björkman A
Article: JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS. 2007;34(5):669-686

Population pharmacokinetics of amodiaquine and desethylamodiaquine in pediatric patients with uncomplicated falciparum malaria.

Hietala SF; Bhattarai A; Msellem M; Röshammar D; Ali AS; Strömberg J; Hombhanje FW; Kaneko A; Björkman A; Ashton M
Article: ACTA TROPICA. 2007;103(2):102-107

Genetic diversity and gene flow of humans, Plasmodium falciparum, and Anopheles farauti s.s. of Vanuatu: inferred malaria dispersal and implications for malaria control.

Lum JK; Kaneko A; Taleo G; Amos M; Reiff DM
Article: JOURNAL OF MEDICAL ENTOMOLOGY. 2007;44(4):601-607

Population structure and gene flow of Anopheles farauti s.s. (Diptera: Culicidae) among ten sites on five islands of Vanuatu: implications for malaria control.

Reiff DM; Kaneko A; Taleo G; Amos M; Lum JK
Article: ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY. 2007;101(4):281-295

Effect of artesunate plus sulfadoxine-pyrimethamine on haematological recovery and anaemia, in Kenyan children with uncomplicated, Plasmodium falciparum malaria.

Obonyo CO; Taylor W; Ekvall H; Kaneko A; Ter Kuile F; Olliaro P; Bjorkman A; Oloo AJ
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2007;51(3):1071-1077

Independent evolution of pyrimethamine resistance in Plasmodium falciparum isolates in Melanesia.

Mita T; Tanabe K; Takahashi N; Tsukahara T; Eto H; Dysoley L; Ohmae H; Kita K; Krudsood S; Looareesuwan S; Kaneko A; Björkman A; Kobayakawa T
Article: INFECTION GENETICS AND EVOLUTION. 2006;6(6):447-452

Rapid selection of dhfr mutant allele in Plasmodium falciparum isolates after the introduction of sulfadoxine/pyrimethamine in combination with 4-aminoquinolines in Papua New Guinea.

Mita T; Kaneko A; Hwaihwanje I; Tsukahara T; Takahashi N; Osawa H; Tanabe K; Kobayakawa T; Björkman A
Article: ACTA TROPICA. 2006;99(1):15-22

Flashback to the 1960s: utility of archived sera to explore the origin and evolution of Plasmodium falciparum chloroquine resistance in the Pacific.

Chan CW; Lynch D; Spathis R; Hombhanje FW; Kaneko A; Garruto RM; Lum JK
Article: ACTA TROPICA. 2006;98(2):137-144

Role of pfmdr1 mutations on chloroquine resistance in Plasmodium falciparum isolates with pfcrt K76T from Papua New Guinea.

Mita T; Kaneko A; Hombhanje F; Hwaihwanje I; Takahashi N; Osawa H; Tsukahara T; Masta A; Lum JK; Kobayakawa T; Ishizaki T; Björkman A
Article: NATURE GENETICS. 2006;38(3):324-330

A SNP in the ABCC11 gene is the determinant of human earwax type.

Yoshiura K-I; Kinoshita A; Ishida T; Ninokata A; Ishikawa T; Kaname T; Bannai M; Tokunaga K; Sonoda S; Komaki R; Ihara M; Saenko VA; Alipov GK; Sekine I; Komatsu K; Takahashi H; Nakashima M; Sosonkina N; Mapendano CK; Ghadami M; Nomura M; Liang D-S; Miwa N; Kim D-K; Garidkhuu A; Natsume N; Ohta T; Tomita H; Kaneko A; Kikuchi M; Russomando G; Hirayama K; Ishibashi M; Takahashi A; Saitou N; Murray JC; Saito S; Nakamura Y; Niikawa N
Article: JAPANESE JOURNAL OF INFECTIOUS DISEASES. 2006;59(1):63-65

Seroprevalence of human herpesvirus 8 in the Vanuatu islands in eastern Melanesia.

Satoh M; Kaneko A; Kokaze A; Katano H; Sata T
Article: JOURNAL OF HUMAN GENETICS. 2006;51(3):244-248

Austronesian origin of the 27-bp deletion of the erythrocyte band 3 gene in East Sepik, Papua New Guinea inferred from mtDNA analysis.

Tsukahara T; Hombhanje FW; Lum JK; Hwaihwanje I; Masta A; Kaneko A; Kobayakawa T
Article: TROPICAL MEDICINE & INTERNATIONAL HEALTH. 2005;10(6):544-549

Associations between frequencies of a susceptible TNF-alpha promoter allele and protective alpha-thalassaemias and malaria parasite incidence in Vanuatu.

Ubalee R; Tsukahara T; Kikuchi M; Lum JK; Dzodzomenyo M; Kaneko A; Hirayama K
Article: PARASITOLOGY INTERNATIONAL. 2005;54(2):109-118

The involvement of neutrophils in the resistance to Leishmania major infection in susceptible but not in resistant mice.

Chen L; Zhang Z-H; Watanabe T; Yamashita T; Kobayakawa T; Kaneko A; Fujiwara H; Sendo F
Article: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. 2005;61(1):15-18

CYP2C8 polymorphism frequencies among malaria patients in Zanzibar.

Cavaco I; Strömberg-Nörklit J; Kaneko A; Msellem MI; Dahoma M; Ribeiro VL; Bjorkman A; Gil JP
Article: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. 2005;59(3):298-301

The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria.

Hombhanje FW; Hwaihwanje I; Tsukahara T; Saruwatari J; Nakagawa M; Osawa H; Paniu MM; Takahashi N; Lum JK; Aumora B; Masta A; Sapuri M; Kobayakawa T; Kaneko A; Ishizaki T
Article: ACTA TROPICA. 2004;91(2):167-175

Anemia and malaria at different altitudes in the western highlands of Kenya.

Akhwale WS; Lum JK; Kaneko A; Eto H; Obonyo C; Björkman A; Kobayakawa T
Article: MOLECULAR AND BIOCHEMICAL PARASITOLOGY. 2004;135(1):159-163

Expansion of wild type allele rather than back mutation in pfcrt explains the recent recovery of chloroquine sensitivity of Plasmodium falciparum in Malawi.

Mita T; Kaneko A; Lum JK; Zungu IL; Tsukahara T; Eto H; Kobayakawa T; Björkman A; Tanabe K
Article: ACTA TROPICA. 2004;90(2):181-185

Malaria dispersal among islands: human mediated Plasmodium falciparum gene flow in Vanuatu, Melanesia.

Lum JK; Kaneko A; Tanabe K; Takahashi N; Björkman A; Kobayakawa T
Article: SCIENCE. 2004;303(5657):493

Stable SNPs in malaria antigen genes in isolated populations.

Tanabe K; Sakihama N; Kaneko A
Article: AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE. 2003;68(4):413-415

Recovery of chloroquine sensitivity and low prevalence of the Plasmodium falciparum chloroquine resistance transporter gene mutation K76T following the discontinuance of chloroquine use in Malawi.

Mita T; Kaneko A; Lum JK; Bwijo B; Takechi M; Zungu IL; Tsukahara T; Tanabe K; Kobayakawa T; Björkman A
Article: ACTA TROPICA. 2003;85(3):363-373

High prevalence of quintuple mutant dhps/dhfr genes in Plasmodium falciparum infections seven years after introduction of sulfadoxine and pyrimethamine as first line treatment in Malawi.

Bwijo B; Kaneko A; Takechi M; Zungu IL; Moriyama Y; Lum JK; Tsukahara T; Mita T; Takahashi N; Bergqvist Y; Björkman A; Kobayakawa T
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2002;99(25):16348-16353

Mosaic organization and heterogeneity in frequency of allelic recombination of the Plasmodium vivax merozoite surface protein-1 locus.

Putaporntip C; Jongwutiwes S; Sakihama N; Ferreira MU; Kho W-G; Kaneko A; Kanbara H; Hattori T; Tanabe K
Article: CHROMATOGRAPHIA. 2002;55(1-2):5-12

Automated solid-phase extraction for determination of amodiaquine, chloroquine and metabolites in capillary blood on sampling paper by liquid chromatography

Lindegårdh N; Forslund M; Green MD; Kaneko A; Bergqvist Y
Article: GENE. 2001;279(1):41-48

Limited recombination events in merozoite surface protein-1 alleles of Plasmodium falciparum on islands.

Sakihama N; Kaneko A; Hattori T; Tanabe K
Article: EXPERIMENTAL PARASITOLOGY. 2001;97(1):50-54

Long PCR amplification of Plasmodium falciparum DNA extracted from filter paper blots.

Sakihama N; Mitamura T; Kaneko A; Horii T; Tanabe K
Article: LANCET. 2000;356(9241):1560-1564

Malaria eradication on islands.

Kaneko A; Taleo G; Kalkoa M; Yamar S; Kobayakawa T; Björkman A
Article: PHARMACOGENETICS AND GENOMICS. 1999;9(5):581-590

High and variable frequencies of CYP2C19 mutations: medical consequences of poor drug metabolism in Vanuatu and other Pacific islands.

Kaneko A; Lum JK; Yaviong L; Takahashi N; Ishizaki T; Bertilsson L; Kobayakawa T; Björkman A
Article: ACTA TROPICA. 1999;73(2):109-119

CD4+ and/or gammadelta+ T cells in the liver spontaneously produce IL-4 in vitro during the early phase of Leishmania major infection in susceptible BALB/c mice.

Yamashita T; Miyata H; Miyaji C; Watanabe H; Abo T; Kobayakawa T; Kaneko A; Sendo F
Article: PHARMACOGENETICS AND GENOMICS. 1999;9(3):317-326

Proguanil disposition and toxicity in malaria patients from Vanuatu with high frequencies of CYP2C19 mutations.

Kaneko A; Bergqvist Y; Taleo G; Kobayakawa T; Ishizaki T; Björkman A
Article: JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES. 1998;719(1-2):141-149

Improved method for the simultaneous determination of proguanil and its metabolites by high-performance liquid chromatography and solid-phase extraction of 100-microl capillary blood samples dried on sampling paper.

Bergqvist Y; Funding L; Kaneko A; Krysén B; Leek T
Article: ACTA TROPICA. 1998;70(3):285-302

Malaria epidemiology, glucose 6-phosphate dehydrogenase deficiency and human settlement in the Vanuatu Archipelago.

Kaneko A; Taleo G; Kalkoa M; Yaviong J; Reeve PA; Ganczakowski M; Shirakawa C; Palmer K; Kobayakawa T; Björkman A
Article: LANCET. 1997;349(9056):921-922

High frequencies of CYP2C19 mutations and poor metabolism of proguanil in Vanuatu.

Kaneko A; Kaneko O; Taleo G; Björkman A; Kobayakawa T
Article: AMERICAN JOURNAL OF HUMAN GENETICS. 1995;56(1):294-301

Multiple glucose 6-phosphate dehydrogenase-deficient variants correlate with malaria endemicity in the Vanuatu archipelago (southwestern Pacific).

Ganczakowski M; Town M; Bowden DK; Vulliamy TJ; Kaneko A; Clegg JB; Weatherall DJ; Luzzatto L
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Review: BMC MEDICINE. 2022;20(1):350

Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data.

Stepniewska K; Allen EN; Humphreys GS; Poirot E; Craig E; Kennon K; Yilma D; Bousema T; Guerin PJ; White NJ; Price RN; Raman J; Martensson A; Mwaiswelo RO; Bancone G; Bastiaens GJH; Bjorkman A; Brown JM; D'Alessandro U; Dicko AA; El-Sayed B; Elzaki S-E; Eziefula AC; Gonçalves BP; Hamid MMA; Kaneko A; Kariuki S; Khan W; Kwambai TK; Ley B; Ngasala BE; Nosten F; Okebe J; Samuels AM; Smit MR; Stone WJR; Sutanto I; Ter Kuile F; Tine RC; Tiono AB; Drakeley CJ; Gosling R; Stergachis A; Barnes KI; Chen I
Letter: JOURNAL OF DERMATOLOGY. 2015;42(8):840-841

Repeated myiasis in a female vulvar squamous cell carcinoma caused by Lucilia sericata and Sarcophaga crassipalpis.

Hiraoka H; Ozawa T; Sowa-Osako J; Ichimura T; Kimata-Teramoto I; Isozumi R; Kaneko A; Tsuruta D
Editorial comment: CLINICAL INFECTIOUS DISEASES. 2012;54(8):1145-1147

Iron deficiency and severe Plasmodium falciparum malaria.

Awah NW; Kaneko A
Editorial comment: ACTA TROPICA. 2010;114(3):129-130

Malaria research--diversity and control: a Sweden-Japan joint seminar.

Kaneko A; Wahlgren M
Published conference paper: ACTA TROPICA. 2010;114(3):177-183

A community-directed strategy for sustainable malaria elimination on islands: short-term MDA integrated with ITNs and robust surveillance.

Kaneko A
Published conference paper: CELL BIOLOGY AND TRANSLATIONAL MEDICINE, VOL 14: STEM CELLS IN LINEAGE SPECIFIC DIFFERENTIATION AND DISEASE. 2003;531:71-82

Malaria on islands. Human and parasite diversities and implications for malaria control in Vanuatu.

Kaneko A
Published conference paper: JOURNAL OF INFECTIOUS DISEASES. 1999;179(4):974-979

Intrinsic efficacy of proguanil against falciparum and vivax malaria independent of the metabolite cycloguanil.

Kaneko A; Bergqvist Y; Takechi M; Kalkoa M; Kaneko O; Kobayakawa T; Ishizaki T; Björkman A

Employments

Professor, Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, 2011-

Degrees and Education

Docent, Karolinska Institutet, 2004
Ph.D, Department of Medicine, Karolinska Institute, 1999
D.T.M. & H., Diploma in Tropical Medicine and Hygiene, Hygiene Faculty of Tropical Medicine, Mahidol University, 1984
M.D., Hirosaki University School of Medicine, 1982

Distinction and awards

The TROPMED Outstanding Alumni Award, Faculty of Tropical Medicine, Mahidol University, 2018
Tropical Medicine Award, , Japanese Society of Tropical Medicine, 2016
Senior Researcher Position grant, 2010 – 2016, Swedish Research Council, 2010
Hohoh Prize, Hirosaki University School of Medicine, Japan, Hirosaki University School of Medicine, Japan, 2006
Tokyo Metropolitan Medical Research Award, Japan, Tokyo Metropolitan, 2001

About me

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