Om mig
Professor emerita i molekylär arbetsmiljömedicin.
Forskningsbeskrivning
Fem utvalda publikationer:
The tryptophan derivative 6-formylindolo[3,2-b]carbazole, FICZ, a dynamic mediator of endogenous aryl hydrocarbon receptor signaling, balances cell growth and differentiation. Rannug A, Rannug U. Crit Rev Toxicol. 2018 Sep 18:1-20.
Chemistry and Properties of Indolocarbazoles. Janosik T, Rannug A, Rannug U, Wahlström N, Slätt J, Bergman J. Chem Rev. 2018 Sep 26;118(18):9058-9128.
The aryl hydrocarbon receptor in barrier organ physiology, immunology, and toxicology. Esser C, Rannug A. Pharmacol Rev. 2015;67(2):259-79.
Inhibition of cytochrome P4501-dependent clearance of the endogenous agonist FICZ as a mechanism for activation of the aryl hydrocarbon receptor. Wincent E, Bengtsson J, Mohammadi Bardbori A, Alsberg T, Luecke S, Rannug U, Rannug A. Proc Natl Acad Sci U S A. 2012 Mar 20;109(12):4479-84.
Certain photooxidized derivatives of tryptophan bind with very high affinity to the Ah receptor and are likely to be endogenous signal substances. Rannug A, Rannug U, Rosenkranz HS, Winqvist L, Westerholm R, Agurell E, Grafström AK. J Biol Chem. 1987 Nov 15;262(32):15422-7.