Adrian Gonon

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: CLINICAL RESEARCH IN CARDIOLOGY. 2020;109(6):655-672

Circulatory factors associated with function and prognosis in patients with severe heart failure.

Rullman E; Melin M; Mandić M; Gonon A; Fernandez-Gonzalo R; Gustafsson T
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2019;63(4):515-522

Effects of thoracic epidural analgesia on exercise-induced myocardial ischaemia in refractory angina pectoris.

Gonon A; Richter A; Cederholm I; Khan J; Novak J; Milovanovic M; Janerot-Sjoberg B
Article: CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING. 2018;38(1):118-127

Effects of enhanced external counterpulsation on skeletal muscle gene expression in patients with severe heart failure.

Melin M; Montelius A; Rydén L; Gonon A; Hagerman I; Rullman E
Article: ACTA PHYSIOLOGICA. 2017;221(3):174-181

Vagal nerve stimulation reduces infarct size via a mechanism involving the alpha-7 nicotinic acetylcholine receptor and downregulation of cardiac and vascular arginase.

Kiss A; Tratsiakovich Y; Mahdi A; Yang J; Gonon AT; Podesser BK; Pernow J
Article: DIABETES & VASCULAR DISEASE RESEARCH. 2017;14(3):236-245

Inhibition of Rho kinase protects from ischaemia-reperfusion injury via regulation of arginase activity and nitric oxide synthase in type 1 diabetes.

Tratsiakovich Y; Kiss A; Gonon AT; Yang J; Sjöquist P-O; Pernow J
Article: PLOS ONE. 2016;11(4):e0153036

Variability in Physical Activity Assessed with Accelerometer Is an Independent Predictor of Mortality in CHF Patients.

Melin M; Hagerman I; Gonon A; Gustafsson T; Rullman E
Article: JOURNAL OF ULTRASOUND IN MEDICINE. 2015;34(9):1599-1605

In Search of the Optimal Heart Perfusion Ultrasound Imaging Platform.

Grishenkov D; Gonon A; Janerot-Sjoberg B
Article: DRUG DESIGN DEVELOPMENT AND THERAPY. 2015;9:2409-2419

Ultrasound contrast agent loaded with nitric oxide as a theranostic microdevice.

Grishenkov D; Gonon A; Weitzberg E; Lundberg JO; Harmark J; Cerroni B; Paradossi G; Janerot-Sjoberg B
Article: PLOS ONE. 2014;9(8):e104731

The role of arginase and rho kinase in cardioprotection from remote ischemic perconditioning in non-diabetic and diabetic rat in vivo.

Kiss A; Tratsiakovich Y; Gonon AT; Fedotovskaya O; Lanner JT; Andersson DC; Yang J; Pernow J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;720(1-3):121-123

Arginase as a target for treatment of myocardial ischemia-reperfusion injury.

Tratsiakovich Y; Yang J; Gonon AT; Sjöquist P-O; Pernow J
Article: INTERNATIONAL JOURNAL OF CARDIOLOGY. 2013;169(1):83-88

Myocardial protection by co-administration of L-arginine and tetrahydrobiopterin during ischemia and reperfusion.

Tratsiakovich Y; Gonon AT; Kiss A; Yang J; Böhm F; Tornvall P; Settergren M; Channon KM; Sjöquist P-O; Pernow J
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013;110(37):15049-15054

Arginase regulates red blood cell nitric oxide synthase and export of cardioprotective nitric oxide bioactivity.

Yang J; Gonon AT; Sjöquist P-O; Lundberg JO; Pernow J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;712(1-3):16-21

Arginase inhibition reduces infarct size via nitric oxide, protein kinase C epsilon and mitochondrial ATP-dependent K+ channels.

Tratsiakovich Y; Gonon AT; Krook A; Yang J; Shemyakin A; Sjöquist P-O; Pernow J
Article: DIABETOLOGIA. 2012;55(3):600-607

The endothelin receptor antagonist bosentan improves peripheral endothelial function in patients with type 2 diabetes mellitus and microalbuminuria: a randomised trial.

Rafnsson A; Böhm F; Settergren M; Gonon A; Brismar K; Pernow J
Article: PLOS ONE. 2012;7(7):e42038

Local arginase inhibition during early reperfusion mediates cardioprotection via increased nitric oxide production.

Gonon AT; Jung C; Katz A; Westerblad H; Shemyakin A; Sjöquist P-O; Lundberg JO; Pernow J
Article: CELLULAR SIGNALLING. 2011;23(5):820-826

Hypoxia followed by re-oxygenation induces oxidation of tyrosine phosphatases.

Sandin A; Dagnell M; Gonon A; Pernow J; Stangl V; Aspenström P; Kappert K; Ostman A
Article: ACTA PHYSIOLOGICA. 2011;201(2):219-226

The combination of L-arginine and ischaemic post-conditioning at the onset of reperfusion limits myocardial injury in the pig.

Gonon AT; Jung C; Yang J; Sjöquist P-O; Pernow J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2011;651(1-3):146-151

Opioid receptor agonist Eribis peptide 94 reduces infarct size in different porcine models for myocardial ischaemia and reperfusion.

Karlsson LO; Grip L; Bissessar E; Bobrova I; Gustafsson T; Kavianipour M; Odenstedt J; Wikström G; Gonon AT
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2010;95(5):2359-2366

Regulation of glucose uptake by endothelin-1 in human skeletal muscle in vivo and in vitro.

Shemyakin A; Salehzadeh F; Böhm F; Al-Khalili L; Gonon A; Wagner H; Efendic S; Krook A; Pernow J
Article: CARDIOVASCULAR RESEARCH. 2010;85(1):147-154

Arginase inhibition mediates cardioprotection during ischaemia-reperfusion.

Jung C; Gonon AT; Sjöquist P-O; Lundberg JO; Pernow J
Article: CARDIOVASCULAR RESEARCH. 2008;78(1):116-122

Adiponectin protects against myocardial ischaemia-reperfusion injury via AMP-activated protein kinase, Akt, and nitric oxide.

Gonon AT; Widegren U; Bulhak A; Salehzadeh F; Persson J; Sjöquist P-O; Pernow J
Article: DIABETES CARE. 2007;30(3):591-596

Dual endothelin receptor blockade acutely improves insulin sensitivity in obese patients with insulin resistance and coronary artery disease.

Ahlborg G; Shemyakin A; Böhm F; Gonon A; Pernow J
Article: BASIC RESEARCH IN CARDIOLOGY. 2007;102(1):80-89

Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor gamma ligand, in relation to nitric oxide.

Gonon AT; Bulhak A; Labruto F; Sjöquist P-O; Pernow J
Article: PEPTIDES. 2005;26(9):1661-1666

The effects of arg-vasopressin on osteoblast-like cells in endothelial nitric oxide synthase-knockout mice and their wild type counterparts.

Lagumdzija A; Pernow Y; Bucht E; Gonon A; Petersson M
Article: CLINICAL SCIENCE. 2005;108(4):357-363

The endothelin-1 receptor antagonist bosentan protects against ischaemia/reperfusion-induced endothelial dysfunction in humans.

Böhm F; Settergren M; Gonon AT; Pernow J
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2005;144(6):860-866

Cardioprotective effect of an endothelin receptor antagonist during ischaemia/reperfusion in the severely atherosclerotic mouse heart.

Gonon AT; Bulhak A; Bröijersén A; Pernow J
Article: REGULATORY PEPTIDES. 2005;125(1-3):173-177

Glucagon-like peptide-1 relaxes rat conduit arteries via an endothelium-independent mechanism.

Nyström T; Gonon AT; Sjöholm A; Pernow J
Article: ACTA PHYSIOLOGICA. 2005;183(2):151-159

Oral pre-treatment with rosuvastatin protects porcine myocardium from ischaemia/reperfusion injury via a mechanism related to nitric oxide but not to serum cholesterol level.

Bulhak AA; Gourine AV; Gonon AT; Sjöquist P-O; Valen G; Pernow J
Article: ACTA PHYSIOLOGICA. 2004;182(1):29-35

Inhibited anabolic effect of insulin-like growth factor-I on stromal bone marrow cells in endothelial nitric oxide synthase-knockout mice.

Lagumdzija A; Ou G; Petersson M; Bucht E; Gonon A; Pernow Y
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2004;286(5):H1767-H1774

Nitric oxide mediates protective effect of endothelin receptor antagonism during myocardial ischemia and reperfusion.

Gonon AT; Erbas D; Bröijersén A; Valen G; Pernow J
Article: JOURNAL OF APPLIED PHYSIOLOGY. 2003;95(6):2218-2222

L-arginine protects from ischemia-reperfusion-induced endothelial dysfunction in humans in vivo.

Pernow J; Bohm F; Beltran E; Gonon A
Article: NITRIC OXIDE-BIOLOGY AND CHEMISTRY. 2002;7(3):210-216

Cardioprotective effect induced by brief exposure to nitric oxide before myocardial ischemia-reperfusion in vivo.

Gourine AV; Bulhak AA; Gonon AT; Pernow J; Sjöquist P-O
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2002;40(3):339-345

Time-dependent cardioprotection with calcium antagonism and experimental studies with clevidipine in ischemic-reperfused pig hearts: part II.

Segawa D; Sjöquist P-O; Wang Q-D; Gonon A; Rydén L
Article: BASIC RESEARCH IN CARDIOLOGY. 2001;96(5):454-462

Limitation of infarct size and attenuation of myeloperoxidase activity by an endothelin A receptor antagonist following ischaemia and reperfusion.

Gonon AT; Gourine AV; Middelveld RJ; Alving K; Pernow J
Article: CARDIOVASCULAR RESEARCH. 2001;51(1):100-107

Short-acting calcium antagonist clevidipine protects against reperfusion injury via local nitric oxide-related mechanisms in the jeopardised myocardium.

Gourine A; Gonon A; Sjöquist PO; Pernow J
Article: EUROPEAN HEART JOURNAL SUPPLEMENTS. 2001;3(C):C22-C27

The role of the endothelium for reperfusion injury

Pernow J; Gonon AT; Gourine A
Article: AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY. 2001;280(3):H1105-H1112

Involvement of nitric oxide in cardioprotective effect of endothelin receptor antagonist during ischemia-reperfusion.

Gourine AV; Gonon AT; Pernow J
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2000;36(3):405-412

Cardioprotection from ischemia and reperfusion injury by an endothelin A-receptor antagonist in relation to nitric oxide production.

Gonon AT; Gourine AV; Pernow J
Article: JOURNAL OF CARDIOVASCULAR PHARMACOLOGY. 2000;36(3):338-343

Calcium antagonist protects the myocardium from reperfusion injury by interfering with mechanisms directly related to reperfusion: an experimental study with the ultrashort-acting calcium antagonist clevidipine.

Segawa D; Sjöquist PO; Wang QD; Gonon A; Nordlander M; Rydén L
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1999;380(2-3):123-128

Cardiac inotropic vs. chronotropic selectivity of isradipine, nifedipine and clevidipine, a new ultrashort-acting dihydropyridine.

Segawa D; Sjöquist PO; Nordlander M; Wang QD; Gonon A; Rydén L
Article: CARDIOVASCULAR RESEARCH. 1998;39(3):674-682

The endothelin A receptor antagonist LU 135252 protects the myocardium from neutrophil injury during ischaemia/reperfusion.

Gonon AT; Wang QD; Pernow J
Article: ACTA PHYSIOLOGICA. 1998;163(4):325-330

Contribution of endothelin to the coronary vasoconstriction in the isolated rat heart induced by nitric oxide synthase inhibition.

Wang QD; Gonon A; Shimizu M; Sjöquist PO; Pernow J
Article: ACTA PHYSIOLOGICA. 1998;163(2):131-137

The novel non-peptide selective endothelin A receptor antagonist LU 135,252 protects against myocardial ischaemic and reperfusion injury in the pig.

Gonon AT; Wang QD; Shimizu M; Pernow J
Article: CARDIOVASCULAR RESEARCH. 1998;38(2):493-499

Calcitonin gene-related peptide in myocardial ischaemia and reperfusion in the pig.

Källner G; Gonon A; Franco-Cereceda A
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Alla övriga publikationer

Editorial comment: JOURNAL OF NUCLEAR CARDIOLOGY. 2022;29(6):3599-3603

Myocardial perfusion imaging performed by dedicated cardiac cadmium-zinc-telluride camera in dextrocardia with situs inversus: A case report.

Forsberg L; Soares M; Gonon A
Letter: CARDIOLOGY. 2006;105(3):162-164

Deadly myocardial fibrosis of unknown etiology in adolescence.

Tornvall P; Lindholm J; Svjatoha V; Gonon A

Anställningar

Anknuten till Forskning, Laboratoriemedicin, Karolinska Institutet, 2024-2026
Anknuten till Forskning, Klinisk vetenskap, intervention och teknik, Karolinska Institutet, 2021-2024

Examina och utbildning

MEDICINE DOKTORSEXAMEN, Institutionen för medicin, Solna, Karolinska Institutet, 2000

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