Adnane Achour

Article: CELL REPORTS. 2023;42(12):113516

The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent.

Middelburg J; Ghaffari S; Schoufour TAW; Sluijter M; Schaap G; Göynük B; Sala BM; Al-Tamimi L; Scheeren F; Franken KLMC; Akkermans JJLL; Cabukusta B; Joosten SA; Derksen I; Neefjes J; van der Burg SH; Achour A; Wijdeven RHM; Weidanz J; van Hall T

Article: COMMUNICATIONS BIOLOGY. 2023;6(1):1193

Combined NMR and molecular dynamics conformational filter identifies unambiguously dynamic ensembles of Dengue protease NS2B/NS3pro.

Agback T; Lesovoy D; Han X; Lomzov A; Sun R; Sandalova T; Orekhov VY; Achour A; Agback P

Article: BIOINFORMATICS. 2023;39(11):btad666

Open MoA: revealing the mechanism of action (MoA) based on network topology and hierarchy.

Liao X; Ozcan M; Shi M; Kim W; Jin H; Li X; Turkez H; Achour A; Uhlén M; Mardinoglu A; Zhang C

Article: CHEMICAL COMMUNICATIONS. 2023;59(36):5475-5478

Resolution enhancement of NMR by decoupling with the low-rank Hankel model.

Qiu T; Jahangiri A; Han X; Lesovoy D; Agback T; Agback P; Achour A; Qu X; Orekhov V

Article: OPEN BIOLOGY. 2023;13(5):220369

Caprin-1 binding to the critical stress granule protein G3BP1 is influenced by pH.

Schulte T; Panas MD; Han X; Williams L; Kedersha N; Fleck JS; Tan TJC; Dopico XC; Olsson A; Morro AM; Hanke L; Nilvebrant J; Giang KA; Nygren P-Å; Anderson P; Achour A; McInerney GM

Article: JOURNAL OF MAGNETIC RESONANCE. 2023;346:107342

NMR spectrum reconstruction as a pattern recognition problem.

Jahangiri A; Han X; Lesovoy D; Agback T; Agback P; Achour A; Orekhov V

Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1230718

Non-classical HLA-E restricted CMV 15-mer peptides are recognized by adaptive NK cells and induce memory responses.

Martín Almazán N; Sala BM; Sandalova T; Sun Y; Resink T; Cichocki F; Söderberg-Nauclér C; Miller JS; Achour A; Sarhan D

Article: ISCIENCE. 2022;25(10):105137

PD-1 expression on mouse intratumoral NK cells and its effects on NK cell phenotype.

Wagner AK; Kadri N; Tibbitt C; van de Ven K; Bagawath-Singh S; Oliinyk D; LeGresley E; Campbell N; Trittel S; Riese P; Ribacke U; Sandalova T; Achour A; Kärre K; Chambers BJ

Article: BIOMOLECULAR NMR ASSIGNMENTS. 2022;16(2):363-371

Assignment of IVL-Methyl side chain of the ligand-free monomeric human MALT1 paracaspase-IgL3 domain in solution.

Han X; Levkovets M; Lesovoy D; Sun R; Wallerstein J; Sandalova T; Agback T; Achour A; Agback P; Orekhov VY

Article: BIOMOLECULAR NMR ASSIGNMENTS. 2022;16(1):135-145

1H, 13C and 15N resonance assignment of backbone and IVL-methyl side chain of the S135A mutant NS3pro/NS2B protein of Dengue II virus reveals unique secondary structure features in solution.

Agback P; Lesovoy DM; Han X; Sun R; Sandalova T; Agback T; Achour A; Orekhov VY

Article: ACS OMEGA. 2022;7(11):9622-9635

l- to d-Amino Acid Substitution in the Immunodominant LCMV-Derived Epitope gp33 Highlights the Sensitivity of the TCR Recognition Mechanism for the MHC/Peptide Structure and Dynamics.

Ballabio F; Broggini L; Paissoni C; Han X; Peqini K; Sala BM; Sun R; Sandalova T; Barbiroli A; Achour A; Pellegrino S; Ricagno S; Camilloni C

Article: FRONTIERS IN IMMUNOLOGY. 2022;13:854312

FOXO1 and FOXO3 Cooperatively Regulate Innate Lymphoid Cell Development.

Luu TT; Søndergaard JN; Peña-Pérez L; Kharazi S; Krstic A; Meinke S; Schmied L; Frengen N; Heshmati Y; Kierczak M; Bouderlique T; Wagner AK; Gustafsson C; Chambers BJ; Achour A; Kutter C; Höglund P; Månsson R; Kadri N

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2021;118(51):e2100687118

A gene-centric approach to biomarker discovery identifies transglutaminase 1 as an epidermal autoantigen.

Landegren N; Ishii N; Aranda-Guillén M; Gunnarsson HI; Sardh F; Hallgren Å; Ståhle M; Hagforsen E; Bradley M; Edqvist P-HD; Pontén F; Mäkitie O; Eidsmo L; Norlén L; Achour A; Dahlbom I; Korponay-Szabó I; Agardh D; Alimohammadi M; Eriksson D; Hashimoto T; Kämpe O

Article: ANTIOXIDANTS. 2021;10(7):1094

A Novel mRNA-Mediated and MicroRNA-Guided Approach to Specifically Eradicate Drug-Resistant Hepatocellular Carcinoma Cell Lines by Se-Methylselenocysteine.

Selvam AK; Jawad R; Gramignoli R; Achour A; Salter H; Björnstedt M

Article: ACS NANO. 2021;15(4):7500-7512

Clustering of Major Histocompatibility Complex-Class I Molecules in Healthy and Cancer Colon Cells Revealed from Their Nanomechanical Properties.

Moretti M; La Rocca R; Perrone Donnorso M; Torre B; Canale C; Malerba M; Das G; Sottile R; Garofalo C; Achour A; Kärre K; Carbone E; Di Fabrizio E

Article: SCIENTIFIC REPORTS. 2020;10(1):22455

The serine protease HtrA plays a key role in heat-induced dispersal of pneumococcal biofilms.

Chao Y; Bergenfelz C; Sun R; Han X; Achour A; Hakansson AP

Article: BIOMOLECULAR NMR ASSIGNMENTS. 2020;14(2):195-200

Assigned NMR backbone resonances of the ligand-binding region domain of the pneumococcal serine-rich repeat protein (PsrP-BR) reveal a rigid monomer in solution.

Schulte T; Sala BM; Nilvebrant J; Nygren P-Å; Achour A; Shernyukov A; Agback T; Agback P

Article: NATURE COMMUNICATIONS. 2020;11(1):4420

An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction.

Hanke L; Vidakovics Perez L; Sheward DJ; Das H; Schulte T; Moliner-Morro A; Corcoran M; Achour A; Karlsson Hedestam GB; Hällberg BM; Murrell B; McInerney GM

Article: PLOS PATHOGENS. 2020;16(9):e1008855

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity.

De Meo S; Dell'Oste V; Molfetta R; Tassinari V; Lotti LV; Vespa S; Pignoloni B; Covino DA; Fantuzzi L; Bona R; Zingoni A; Nardone I; Biolatti M; Coscia A; Paolini R; Benkirane M; Edfors F; Sandalova T; Achour A; Hiscott J; Landolfo S; Santoni A; Cerboni C

Article: BMC IMMUNOLOGY. 2020;21(1):27

Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis.

Gerstner C; Turcinov S; Hensvold AH; Chemin K; Uchtenhagen H; Ramwadhdoebe TH; Dubnovitsky A; Kozhukh G; Rönnblom L; Kwok WW; Achour A; Catrina AI; van Baarsen LGM; Malmström V

Article: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2020;21(9):E3235-3235

Glycosylation Tunes Neuroserpin Physiological and Pathological Properties.

Visentin C; Broggini L; Sala BM; Russo R; Barbiroli A; Santambrogio C; Nonnis S; Dubnovitsky A; Bolognesi M; Miranda E; Achour A; Ricagno S

Article: PLOS PATHOGENS. 2020;16(5):e1008244

Tuning antiviral CD8 T-cell response via proline-altered peptide ligand vaccination.

Duru AD; Sun R; Allerbring EB; Chadderton J; Kadri N; Han X; Peqini K; Uchtenhagen H; Madhurantakam C; Pellegrino S; Sandalova T; Nygren P-Å; Turner SJ; Achour A

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2020;50(4):494-504

IL-15 and CD155 expression regulate LAT expression in murine DNAM1+ NK cells, enhancing their effectors functions.

Luu TT; Wagner AK; Schmied L; Meinke S; Freund JE; Kambayashi T; Ravens I; Achour A; Bernhardt G; Chambers BJ; Höglund P; Kadri N

Article: FEBS JOURNAL. 2020;287(3):546-560

Biochemical and biophysical comparison of human and mouse beta-2 microglobulin reveals the molecular determinants of low amyloid propensity.

Achour A; Broggini L; Han X; Sun R; Santambrogio C; Buratto J; Visentin C; Barbiroli A; De Luca CMG; Sormanni P; Moda F; De Simone A; Sandalova T; Grandori R; Camilloni C; Ricagno S

Article: FRONTIERS IN IMMUNOLOGY. 2020;11:437

Interaction With 14-3-3 Correlates With Inactivation of the RIG-I Signalosome by Herpesvirus Ubiquitin Deconjugases.

Gupta S; Ylä-Anttila P; Sandalova T; Achour A; Masucci MG

Article: ARTHRITIS & RHEUMATOLOGY. 2020;72(1):179-191

Proinflammatory Histidyl-Transfer RNA Synthetase-Specific CD4+ T Cells in the Blood and Lungs of Patients With Idiopathic Inflammatory Myopathies.

Galindo-Feria AS; Albrecht I; Fernandes-Cerqueira C; Notarnicola A; James EA; Herrath J; Dastmalchi M; Sandalova T; Rönnblom L; Jakobsson P-J; Fathi M; Achour A; Grunewald J; Malmström V; Lundberg IE

Article: PLOS PATHOGENS. 2019;15(11):e1008146

14-3-3 scaffold proteins mediate the inactivation of trim25 and inhibition of the type I interferon response by herpesvirus deconjugases.

Gupta S; Ylä-Anttila P; Sandalova T; Sun R; Achour A; Masucci MG

Article: JCI INSIGHT. 2019;5(9):126492

B cell profiling in malaria reveals expansion and remodelling of CD11c+ B cell subsets.

Sundling C; Rönnberg C; Yman V; Asghar M; Jahnmatz P; Lakshmikanth T; Chen Y; Mikes J; Forsell MN; Sondén K; Achour A; Brodin P; Persson KE; Färnert A

Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2019;116(11):5055-5060

Successive crystal structure snapshots suggest the basis for MHC class I peptide loading and editing by tapasin.

Hafstrand I; Sayitoglu EC; Apavaloaei A; Josey BJ; Sun R; Han X; Pellegrino S; Ozkazanc D; Potens R; Janssen L; Nilvebrant J; Nygren P-Å; Sandalova T; Springer S; Georgoudaki A-M; Duru AD; Achour A

Article: EBIOMEDICINE. 2019;40:517-527

B cell alterations during BAFF inhibition with belimumab in SLE.

Ramsköld D; Parodis I; Lakshmikanth T; Sippl N; Khademi M; Chen Y; Zickert A; Mikeš J; Achour A; Amara K; Piehl F; Brodin P; Gunnarsson I; Malmström V

Article: AUTOIMMUNITY. 2019;52(1):1-11

Individual and stable autoantibody repertoires in healthy individuals.

Neiman M; Hellström C; Just D; Mattsson C; Fagerberg L; Schuppe-Koistinen I; Gummesson A; Bergström G; Kallioniemi O; Achour A; Sallinen R; Uhlén M; Nilsson P

Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2019;89(1):e12732

Effect of CTLA4-Ig (abatacept) treatment on T cells and B cells in peripheral blood of patients with polymyositis and dermatomyositis.

Tang Q; Ramsköld D; Krystufkova O; Mann HF; Wick C; Dastmalchi M; Lakshmikanth T; Chen Y; Mikes J; Alexanderson H; Achour A; Brodin P; Vencovsky J; Lundberg IE; Malmström V

Article: NATURE MICROBIOLOGY. 2019;4(1):62-70

Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.

Subramanian K; Neill DR; Malak HA; Spelmink L; Khandaker S; Dalla Libera Marchiori G; Dearing E; Kirby A; Yang M; Achour A; Nilvebrant J; Nygren P-Å; Plant L; Kadioglu A; Henriques-Normark B

Article: FRONTIERS IN IMMUNOLOGY. 2019;10:2249

The Complement System Is Essential for the Phagocytosis of Mesenchymal Stromal Cells by Monocytes.

Gavin C; Meinke S; Heldring N; Heck KA; Achour A; Iacobaeus E; Höglund P; Le Blanc K; Kadri N

Article: ANALYTICA CHIMICA ACTA. 2018;1025:118-123

Bioanalytical advantages of a novel recombinant apyrase enzyme in ATP-based bioluminescence methods.

Pavankumar AR; Zelenin S; Lundin A; Schulte T; Rajarathinam K; Rebellato P; Ardabili S; Salas J; Achour A; Russom A

Article: JOURNAL OF AUTOIMMUNITY. 2018;92:47-56

Memory T cells specific to citrullinated α-enolase are enriched in the rheumatic joint.

Pieper J; Dubnovitsky A; Gerstner C; James EA; Rieck M; Kozhukh G; Tandre K; Pellegrino S; Gebe JA; Rönnblom L; Sandalova T; Kwok WW; Klareskog L; Buckner JH; Achour A; Malmström V

Article: IMMUNOHORIZONS. 2018;2(6):172-184

Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection.

Lampen MH; Uchtenhagen H; Blom K; Varnaitė R; Pakalniene J; Dailidyte L; Wälchli S; Lindquist L; Mickiene A; Michaëlsson J; Schumacher TN; Ljunggren H-G; Sandberg JK; Achour A; Gredmark-Russ S

Article: APPLIED MICROBIOLOGY AND BIOTECHNOLOGY. 2018;102(9):4193-4201

Detecting ligand interactions in real time on living bacterial cells.

Encarnação JC; Schulte T; Achour A; Björkelund H; Andersson K

Article: JOURNAL OF IMMUNOLOGY. 2018;200(8):2860-2868

The Immunogenicity of a Proline-Substituted Altered Peptide Ligand toward the Cancer-Associated TEIPP Neoepitope Trh4 Is Unrelated to Complex Stability.

Hafstrand I; Doorduijn EM; Sun R; Talyzina A; Sluijter M; Pellegrino S; Sandalova T; Duru AD; van Hall T; Achour A

Article: JOURNAL OF CLINICAL INVESTIGATION. 2018;128(4):1523-1537

LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions.

Yu K; Davidson CL; Wójtowicz A; Lisboa L; Wang T; Airo AM; Villard J; Buratto J; Sandalova T; Achour A; Humar A; Boggian K; Cusini A; van Delden C; Egli A; Manuel O; Mueller N; Bochud P-Y; Swiss Transplant Cohort Study; Burshtyn DN

Article: OPEN BIOLOGY. 2018;8(4):170248

Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in Streptococcus pneumoniae.

Han X; Sun R; Sandalova T; Achour A

Article: FRONTIERS IN IMMUNOLOGY. 2018;9:926

MICA-129 Dimorphism and Soluble MICA Are Associated With the Progression of Multiple Myeloma.

Zingoni A; Vulpis E; Cecere F; Amendola MG; Fuerst D; Saribekyan T; Achour A; Sandalova T; Nardone I; Peri A; Soriani A; Fionda C; Mariggiò E; Petrucci MT; Ricciardi MR; Mytilineos J; Cippitelli M; Cerboni C; Santoni A

Article: JOURNAL OF NEUROIMMUNOLOGY. 2017;303:1-12

Nitration of MOG diminishes its encephalitogenicity depending on MHC haplotype.

Warnecke A; Musunuri S; N'diaye M; Sandalova T; Achour A; Bergquist J; Harris RA

Article: FRONTIERS IN IMMUNOLOGY. 2017;8:1130

Mass Cytometry Identifies Distinct Lung CD4+ T Cell Patterns in Löfgren's Syndrome and Non-Löfgren's Syndrome Sarcoidosis.

Kaiser Y; Lakshmikanth T; Chen Y; Mikes J; Eklund A; Brodin P; Achour A; Grunewald J

Article: FRONTIERS IN IMMUNOLOGY. 2017;8:717

Combining Flow and Mass Cytometry in the Search for Biomarkers in Chronic Graft-versus-Host Disease.

Stikvoort A; Chen Y; Rådestad E; Törlén J; Lakshmikanth T; Björklund A; Mikes J; Achour A; Gertow J; Sundberg B; Remberger M; Sundin M; Mattsson J; Brodin P; Uhlin M

Article: PLOS ONE. 2017;12(12):e0189584

Crystal structures of H-2Db in complex with the LCMV-derived peptides GP92 and GP392 explain pleiotropic effects of glycosylation on antigen presentation and immunogenicity.

Hafstrand I; Badia-Martinez D; Josey BJ; Norström M; Buratto J; Pellegrino S; Duru AD; Sandalova T; Achour A

Article: CELLULAR MICROBIOLOGY. 2016;18(11):1537-1550

Migratory activation of parasitized dendritic cells by the protozoan Toxoplasma gondii 14-3-3 protein.

Weidner JM; Kanatani S; Uchtenhagen H; Varas-Godoy M; Schulte T; Engelberg K; Gubbels M-J; Sun HS; Harrison RE; Achour A; Barragan A

Article: SCIENTIFIC REPORTS. 2016;6:32371

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation.

Schulte T; Mikaelsson C; Beaussart A; Kikhney A; Deshmukh M; Wolniak S; Pathak A; Ebel C; Löfling J; Fogolari F; Henriques-Normark B; Dufrêne YF; Svergun D; Nygren P-Å; Achour A

Article: MOLECULAR MICROBIOLOGY. 2016;101(6):954-967

The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.

Sandalova T; Lee M; Henriques-Normark B; Hesek D; Mobashery S; Mellroth P; Achour A

Article: OPEN BIOLOGY. 2016;6(7):160078

Combined structural, biochemical and cellular evidence demonstrates that both FGDF motifs in alphavirus nsP3 are required for efficient replication.

Schulte T; Liu L; Panas MD; Thaa B; Dickson N; Götte B; Achour A; McInerney GM

Article: JOURNAL OF IMMUNOLOGY. 2016;196(5):2327-2334

The MHC Class I Cancer-Associated Neoepitope Trh4 Linked with Impaired Peptide Processing Induces a Unique Noncanonical TCR Conformer.

Hafstrand I; Doorduijn EM; Duru AD; Buratto J; Oliveira CC; Sandalova T; van Hall T; Achour A

Article: EUROPEAN RESPIRATORY JOURNAL. 2016;47(3):898-909

T-cell receptor-HLA-DRB1 associations suggest specific antigens in pulmonary sarcoidosis.

Grunewald J; Kaiser Y; Ostadkarampour M; Rivera NV; Vezzi F; Lötstedt B; Olsen R-A; Sylwan L; Lundin S; Käller M; Sandalova T; Ahlgren KM; Wahlström J; Achour A; Ronninger M; Eklund A

Article: JOURNAL OF CLINICAL INVESTIGATION. 2016;126(2):784-794

TAP-independent self-peptides enhance T cell recognition of immune-escaped tumors.

Doorduijn EM; Sluijter M; Querido BJ; Oliveira CC; Achour A; Ossendorp F; van der Burg SH; van Hall T

Article: FRONTIERS IN IMMUNOLOGY. 2016;7:494

Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted α-Enolase T Cell Epitope in Rheumatoid Arthritis.

Gerstner C; Dubnovitsky A; Sandin C; Kozhukh G; Uchtenhagen H; James EA; Rönnelid J; Ytterberg AJ; Pieper J; Reed E; Tandre K; Rieck M; Zubarev RA; Rönnblom L; Sandalova T; Buckner JH; Achour A; Malmström V

Article: CELL REPORTS. 2015;10(9):1626-1638

Microglia-Secreted Galectin-3 Acts as a Toll-like Receptor 4 Ligand and Contributes to Microglial Activation.

Burguillos MA; Svensson M; Schulte T; Boza-Serrano A; Garcia-Quintanilla A; Kavanagh E; Santiago M; Viceconte N; Oliva-Martin MJ; Osman AM; Salomonsson E; Amar L; Persson A; Blomgren K; Achour A; Englund E; Leffler H; Venero JL; Joseph B; Deierborg T

Article: PLOS PATHOGENS. 2015;11(2):e1004659

Viral and cellular proteins containing FGDF motifs bind G3BP to block stress granule formation.

Panas MD; Schulte T; Thaa B; Sandalova T; Kedersha N; Achour A; McInerney GM

Article: PLOS ONE. 2015;10(3):e0118898

Binding of subdomains 1/2 of PfEMP1-DBL1α to heparan sulfate or heparin mediates Plasmodium falciparum rosetting.

Angeletti D; Sandalova T; Wahlgren M; Achour A

Article: BMC BIOINFORMATICS. 2014;15(1):370

PyTMs: a useful PyMOL plugin for modeling common post-translational modifications.

Warnecke A; Sandalova T; Achour A; Harris RA

Article: JOURNAL OF CELL SCIENCE. 2014;127(Pt 13):2885-2897

Peptide-independent stabilization of MHC class I molecules breaches cellular quality control.

Hein Z; Uchtenhagen H; Abualrous ET; Saini SK; Janßen L; Van Hateren A; Wiek C; Hanenberg H; Momburg F; Achour A; Elliott T; Springer S; Boulanger D

Article: JOURNAL OF IMMUNOLOGY. 2014;192(12):5802-5812

Boosting of HIV-1 neutralizing antibody responses by a distally related retroviral envelope protein.

Uchtenhagen H; Schiffner T; Bowles E; Heyndrickx L; LaBranche C; Applequist SE; Jansson M; De Silva T; Back JW; Achour A; Scarlatti G; Fomsgaard A; Montefiori D; Stewart-Jones G; Spetz A-L

Article: IMMUNOBIOLOGY. 2014;219(3):189-197

Melanocortin 1 Receptor-derived peptides are efficiently recognized by cytotoxic T lymphocytes from melanoma patients.

González FE; Ramírez M; Allerbring EB; Fasching N; Lundqvist A; Poschke I; Achour A; Salazar-Onfray F

Article: MBIO. 2014;5(1):e01120-e01113

Structural and functional insights into peptidoglycan access for the lytic amidase LytA of Streptococcus pneumoniae.

Mellroth P; Sandalova T; Kikhney A; Vilaplana F; Hesek D; Lee M; Mobashery S; Normark S; Svergun D; Henriques-Normark B; Achour A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2014;289(6):3318-3327

Class I major histocompatibility complex, the trojan horse for secretion of amyloidogenic β2-microglobulin.

Halabelian L; Ricagno S; Giorgetti S; Santambrogio C; Barbiroli A; Pellegrino S; Achour A; Grandori R; Marchese L; Raimondi S; Mangione PP; Esposito G; Al-Shawi R; Simons JP; Speck I; Stoppini M; Bolognesi M; Bellotti V

Article: OPEN BIOLOGY. 2014;4(1):130090

The basic keratin 10-binding domain of the virulence-associated pneumococcal serine-rich protein PsrP adopts a novel MSCRAMM fold.

Schulte T; Löfling J; Mikaelsson C; Kikhney A; Hentrich K; Diamante A; Ebel C; Normark S; Svergun D; Henriques-Normark B; Achour A

Article: PLOS ONE. 2014;9(10):e111041

Designing a multimer allergen for diagnosis and immunotherapy of dog allergic patients.

Nilsson OB; Neimert-Andersson T; Bronge M; Grundström J; Sarma R; Uchtenhagen H; Kikhney A; Sandalova T; Holmgren E; Svergun D; Achour A; van Hage M; Grönlund H

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2013;43(11):3051-3060

Proline substitution independently enhances H-2D(b) complex stabilization and TCR recognition of melanoma-associated peptides.

Uchtenhagen H; Abualrous ET; Stahl E; Allerbring EB; Sluijter M; Zacharias M; Sandalova T; van Hall T; Springer S; Nygren P-Å; Achour A

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2013;43(4):1042-1052

Cis association of leukocyte Ig-like receptor 1 with MHC class I modulates accessibility to antibodies and HCMV UL18.

Li NL; Fu L; Uchtenhagen H; Achour A; Burshtyn DN

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2012;42(11):2990-3000

Unexpected T-cell recognition of an altered peptide ligand is driven by reversed thermodynamics.

Allerbring EB; Duru AD; Uchtenhagen H; Madhurantakam C; Tomek MB; Grimm S; Mazumdar PA; Friemann R; Uhlin M; Sandalova T; Nygren P-Å; Achour A

Article: PLOS ONE. 2012;7(3):e32805

Inflammation-associated nitrotyrosination affects TCR recognition through reduced stability and alteration of the molecular surface of the MHC complex.

Madhurantakam C; Duru AD; Sandalova T; Webb JR; Achour A

Article: PLOS ONE. 2012;7(12):e50758

Plasmodium falciparum rosetting epitopes converge in the SD3-loop of PfEMP1-DBL1α.

Angeletti D; Albrecht L; Blomqvist K; Quintana MDP; Akhter T; Bächle SM; Sawyer A; Sandalova T; Achour A; Wahlgren M; Moll K

Article: PLOS ONE. 2011;6(4):e18767

Crystal structure of the HIV-2 neutralizing Fab fragment 7C8 with high specificity to the V3 region of gp125.

Uchtenhagen H; Friemann R; Raszewski G; Spetz A-L; Nilsson L; Achour A

Article: PLOS ONE. 2011;6(12):e29523

Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).

Anedda F; Zucchelli M; Schepis D; Hellquist A; Corrado L; D'Alfonso S; Achour A; McInerney G; Bertorello A; Lördal M; Befrits R; Björk J; Bresso F; Törkvist L; Halfvarson J; Kere J; D'Amato M

Article: PLOS ONE. 2011;6(6):e20135

Increased sensitivity to broadly neutralizing antibodies of end-stage disease R5 HIV-1 correlates with evolution in Env glycosylation and charge.

Borggren M; Repits J; Sterjovski J; Uchtenhagen H; Churchill MJ; Karlsson A; Albert J; Achour A; Gorry PR; Fenyö EM; Jansson M

Article: PLOS ONE. 2010;5(10):e13174

Natural killer cell tolerance persists despite significant reduction of self MHC class I on normal target cells in mice.

Brodin P; Lakshmikanth T; Mehr R; Johansson MH; Duru AD; Achour A; Salmon-Divon M; Kärre K; Höglund P; Johansson S

Article: JOURNAL OF IMMUNOLOGY. 2010;185(6):3574-3582

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block.

Strandberg LS; Ambrosi A; Jagodic M; Dzikaite V; Janson P; Khademi M; Salomonsson S; Ottosson L; Klauninger R; Adén U; Sonesson S-E; Sunnerhagen M; de Graaf KL; Kuchroo VK; Achour A; Winqvist O; Olsson T; Wahren-Herlenius M

Article: PLOS PATHOGENS. 2010;6(9):e1001084

Generation of neutralizing antibodies and divergence of SIVmac239 in cynomolgus macaques following short-term early antiretroviral therapy.

Ozkaya Sahin G; Bowles EJ; Parker J; Uchtenhagen H; Sheik-Khalil E; Taylor S; Pybus OG; Mäkitalo B; Walther-Jallow L; Spångberg M; Thorstensson R; Achour A; Fenyö EM; Stewart-Jones GBE; Spetz A-L

Article: JOURNAL OF MOLECULAR BIOLOGY. 2010;401(1):68-83

Crystal structure of the dog lipocalin allergen Can f 2: implications for cross-reactivity to the cat allergen Fel d 4.

Madhurantakam C; Nilsson OB; Uchtenhagen H; Konradsen J; Saarne T; Högbom E; Sandalova T; Grönlund H; Achour A

Article: JOURNAL OF MOLECULAR BIOLOGY. 2009;393(3):704-716

Two crystal structures of pneumococcal pilus sortase C provide novel insights into catalysis and substrate specificity.

Neiers F; Madhurantakam C; Fälker S; Manzano C; Dessen A; Normark S; Henriques-Normark B; Achour A

Article: CANCER RESEARCH. 2009;69(19):7784-7792

Design of agonistic altered peptides for the robust induction of CTL directed towards H-2Db in complex with the melanoma-associated epitope gp100.

van Stipdonk MJB; Badia-Martinez D; Sluijter M; Offringa R; van Hall T; Achour A

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2009;65(Pt 7):705-708

Production, purification, crystallization and preliminary X-ray diffraction analysis of the HIV-2-neutralizing V3 loop-specific Fab fragment 7C8.

Uchtenhagen H; Sourial S; Friemann R; Ehnlund M; Spetz A-L; Harris RA; Madhurantakam C; Achour A

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2009;65(Pt 5):467-471

Production, crystallization and preliminary X-ray diffraction analysis of the allergen Can f 2 from Canis familiaris.

Madhurantakam C; Nilsson OB; Jönsson K; Grönlund H; Achour A

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2009;65(Pt 1):55-58

Cloning, expression, purification, crystallization and preliminary X-ray analysis of the pilus-associated sortase C from Streptococcus pneumoniae.

Neiers F; Madhurantakam C; Fälker S; Normark S; Henriques-Normark B; Achour A

Article: MOLECULAR IMMUNOLOGY. 2008;46(2):294-303

Mutational analysis of amino acid residues involved in IgE-binding to the Malassezia sympodialis allergen Mala s 11.

Vilhelmsson M; Glaser AG; Martinez DB; Schmidt M; Johansson C; Rhyner C; Berndt KD; Scheynius A; Crameri R; Achour A; Zargari A

Article: VIROLOGY. 2008;379(1):125-134

Primary HIV-1 R5 isolates from end-stage disease display enhanced viral fitness in parallel with increased gp120 net charge.

Repits J; Sterjovski J; Badia-Martinez D; Mild M; Gray L; Churchill MJ; Purcell DFJ; Karlsson A; Albert J; Fenyö EM; Achour A; Gorry PR; Jansson M

Article: JOURNAL OF LEUKOCYTE BIOLOGY. 2008;83(1):56-63

Human cytomegalovirus-derived protein UL18 alters the phenotype and function of monocyte-derived dendritic cells.

Wagner CS; Walther-Jallow L; Buentke E; Ljunggren H-G; Achour A; Chambers BJ

Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;373(3):695-705

Structural elements underlying the high binding affinity of human cytomegalovirus UL18 to leukocyte immunoglobulin-like receptor-1.

Wagner CS; Rölle A; Cosman D; Ljunggren H-G; Berndt KD; Achour A

Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;370(4):714-727

Structural characterization of the tetrameric form of the major cat allergen Fel d 1.

Kaiser L; Velickovic TC; Badia-Martinez D; Adedoyin J; Thunberg S; Hallén D; Berndt K; Grönlund H; Gafvelin G; van Hage M; Achour A

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2007;37(7):1986-1995

Malondialdehyde modification of myelin oligodendrocyte glycoprotein leads to increased immunogenicity and encephalitogenicity.

Wållberg M; Bergquist J; Achour A; Breij E; Harris RA

Article: JOURNAL OF MOLECULAR BIOLOGY. 2007;369(4):1079-1086

Crystal structure of the major Malassezia sympodialis allergen Mala s 1 reveals a beta-propeller fold: a novel fold among allergens.

Vilhelmsson M; Zargari A; Crameri R; Rasool O; Achour A; Scheynius A; Hallberg BM

Article: CURRENT HIV RESEARCH. 2006;4(2):229-237

Deletion of the V1/V2 region does not increase the accessibility of the V3 region of recombinant gp125.

Sourial S; Nilsson C; Wärnmark A; Achour A; Harris RA

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2006;281(13):8950-8957

Dissection of the interaction of the human cytomegalovirus-derived US2 protein with major histocompatibility complex class I molecules: prominent role of a single arginine residue in human leukocyte antigen-A2.

Thilo C; Berglund P; Applequist SE; Yewdell JW; Ljunggren H-G; Achour A

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2006;36(3):732-741

Spontaneous mutations in the human CMV HLA class I homologue UL18 affect its binding to the inhibitory receptor LIR-1/ILT2/CD85j.

Cerboni C; Achour A; Wärnmark A; Mousavi-Jazi M; Sandalova T; Hsu M-L; Cosman D; Kärre K; Carbone E

Article: JOURNAL OF MOLECULAR BIOLOGY. 2006;356(2):382-396

Structural basis of the differential stability and receptor specificity of H-2Db in complex with murine versus human beta2-microglobulin.

Achour A; Michaëlsson J; Harris RA; Ljunggren H-G; Kärre K; Schneider G; Sandalova T

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2006;62(Pt 2):97-99

Crystallization and preliminary crystallographic study of the yeast Malassezia sympodialis allergen Mala s 1.

Vilhelmsson M; Hallberg BM; Rasool O; Zargari A; Scheynius A; Achour A

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2005;61(Pt 12):1090-1093

Expression, refolding and crystallization of murine MHC class I H-2Db in complex with human beta2-microglobulin.

Sandalova T; Michaëlsson J; Harris RA; Ljunggren H-G; Kärre K; Schneider G; Achour A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2005;280(29):27069-27075

A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity.

Sandalova T; Michaëlsson J; Harris RA; Odeberg J; Schneider G; Kärre K; Achour A

Article: MOLECULAR BIOTECHNOLOGY. 2005;30(2):155-162

Cloning, expression, and purification of HIV-2 gp125: A target for HIV vaccination.

Sourial S; Wärnmark A; Nilsson C; Björling E; Achour A; Harris RA

Article: ACTA CRYSTALLOGRAPHICA SECTION F: STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2005;61(Pt 2):232-234

Crystallization and preliminary crystallographic data of a Fel d 1 (1+2) construct corresponding to the major allergen from cat.

Kaiser L; Grönlund H; van Hage-Hamsten M; Achour A

Article: JOURNAL OF IMMUNOLOGY. 2004;172(9):5504-5511

Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.

Velloso LM; Michaëlsson J; Ljunggren H-G; Schneider G; Achour A

Article: JOURNAL OF BIOLOGICAL CHEMISTRY. 2003;278(39):37730-37735

The crystal structure of the major cat allergen Fel d 1, a member of the secretoglobin family.

Kaiser L; Grönlund H; Sandalova T; Ljunggren H-G; van Hage-Hamsten M; Achour A; Schneider G

Article: INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. 2003;132(1):25-26

Three-dimensional structure of Fel d 1, the major allergen in cat.

Kaiser L; Grönlund H; Sandalova T; Ljunggren H-G; Achour A; Schneider G; van Hage-Hamsten M

Article: ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY. 2003;59(Pt 6):1103-1105

Production, crystallization and preliminary crystallographic study of the major cat allergen Fel d 1.

Kaiser L; Grönlund H; Sandalova T; Ljunggren H-G; Schneider G; van Hage-Hamsten M; Achour A

Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2002;196(11):1403-1414

A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition.

Michaëlsson J; Teixeira de Matos C; Achour A; Lanier LL; Kärre K; Söderström K

Article: IMMUNITY. 2002;17(6):757-768

A structural basis for LCMV immune evasion: subversion of H-2D(b) and H-2K(b) presentation of gp33 revealed by comparative crystal structure.Analyses.

Achour A; Michaëlsson J; Harris RA; Odeberg J; Grufman P; Sandberg JK; Levitsky V; Kärre K; Sandalova T; Schneider G

Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2002;55(2):129-139

The role of an exposed loop in the alpha2 domain in the mouse MHC class I H-2Dd molecule for recognition by the monoclonal antibody 34-5-8S and the NK-cell receptor Ly49A.

Waldenström M; Achour A; Michaelsson J; Rölle A; Kärre K

Article: JOURNAL OF IMMUNOLOGY. 2002;168(2):793-800

NK cell inhibitory receptor Ly-49C residues involved in MHC class I binding.

Sundbäck J; Achour A; Michaëlsson J; Lindström H; Kärre K

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2001;31(12):3602-3611

The identification of a common pathogen-specific HLA class I A*0201-restricted cytotoxic T cell epitope encoded within the heat shock protein 65.

Charo J; Geluk A; Sundbäck M; Mirzai B; Diehl AD; Malmberg KJ; Achour A; Huriguchi S; van Meijgaarden KE; Drijfhout JW; Beekman N; van Veelen P; Ossendorp F; Ottenhoff TH; Kiessling R

Article: JOURNAL OF IMMUNOLOGY. 2001;166(12):7327-7334

MHC class I recognition by NK receptors in the Ly49 family is strongly influenced by the beta 2-microglobulin subunit.

Michaëlsson J; Achour A; Rölle A; Kärre K

Article: VIROLOGY. 2000;273(1):112-119

Human immunodeficiency virus type 1 Nef epitopes recognized in HLA-A2 transgenic mice in response to DNA and peptide immunization.

Sandberg JK; Leandersson AC; Devito C; Kohleisen B; Erfle V; Achour A; Levi M; Schwartz S; Kärre K; Wahren B; Hinkula J

Article: JOURNAL OF IMMUNOLOGY. 2000;165(1):25-33

T cell tolerance based on avidity thresholds rather than complete deletion allows maintenance of maximal repertoire diversity.

Sandberg JK; Franksson L; Sundbäck J; Michaelsson J; Petersson M; Achour A; Wallin RP; Sherman NE; Bergman T; Jörnvall H; Hunt DF; Kiessling R; Kärre K

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 2000;30(1):300-307

Visualization of inhibitory Ly49 receptor specificity with soluble major histocompatibility complex class I tetramers.

Michaëlsson J; Achour A; Salcedo M; Kâse-Sjöström A; Sundbäck J; Harris RA; Kärre K

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1999;29(9):2748-2758

Peptide dependency and selectivity of the NK cell inhibitory receptor Ly-49C.

Franksson L; Sundbäck J; Achour A; Bernlind J; Glas R; Kärre K

Article: ACTA CRYSTALLOGRAPHICA SECTION D: BIOLOGICAL CRYSTALLOGRAPHY. 1999;55(Pt 1):260-262

Murine class I major histocompatibility complex H-2Dd: expression, refolding and crystallization.

Achour A; Harris RA; Persson K; Sundbäck J; Sentman CL; Schneider G; Lindqvist Y; Kärre K

Article: VIRAL IMMUNOLOGY. 1999;12(1):79-88

Characterization of neutralizing sites in the second variable and fourth variable region in gp125 and a conserved region in gp36 of human immunodeficiency virus type 2.

Skott P; Achour A; Norin M; Thorstensson R; Björling E

Article: VIRUS RESEARCH. 1999;59(1):49-60

Fine characterization of a V3-region neutralizing epitope in human immunodeficiency virus type 2.

Mörner A; Achour A; Norin M; Thorstensson R; Björling E

Article: EUROPEAN JOURNAL OF IMMUNOLOGY. 1998;28(9):2872-2881

Impaired MHC class I (H-2Dd)-mediated protection against Ly-49A+ NK cells after amino acid substitutions in the antigen binding cleft.

Waldenström M; Sundbäck J; Olsson-Alheim MY; Achour A; Kärre K

Article: IMMUNITY. 1998;9(2):199-208

The crystal structure of H-2Dd MHC class I complexed with the HIV-1-derived peptide P18-I10 at 2.4 A resolution: implications for T cell and NK cell recognition.

Achour A; Persson K; Harris RA; Sundbäck J; Sentman CL; Lindqvist Y; Schneider G; Kärre K

Article: INTERNATIONAL IMMUNOLOGY. 1998;10(2):131-140

A three-dimensional model of the Fas/APO-1 molecule: cross-reactivity of anti-Fas antibodies explained by structural mimicry of antigenic sites.

Fadeel B; Lindberg J; Achour A; Chiodi F

Article: MOLECULAR IMMUNOLOGY. 1995;32(11):789-794

Altered MHC class I presented peptide repertoire is not sufficient to induce NK cell mediated F1-hybrid resistance.

Salcedo M; Höglund P; Achour A; Thorpe CJ; Ljunggren HG

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