Aase Hensvold

Publikationer
CV
Populärvetenskap och samverkan

Artiklar

Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2023;52(5):460-467

The Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: predicting clinical arthritis development.

van Boheemen L; Ter Wee MM; Falahee M; Filer A; van Beers-Tas M; Finckh A; Hensvold A; Raza K; van Schaardenburg D
Article: JOURNAL OF AUTOIMMUNITY. 2023;136:103022

The human bone marrow plasma cell compartment in rheumatoid arthritis - Clonal relationships and anti-citrulline autoantibody producing cells.

Hensvold A; Horuluoglu B; Sahlström P; Thyagarajan R; Diaz Boada JS; Hansson M; Mathsson-Alm L; Gerstner C; Sippl N; Israelsson L; Wedin R; Steen J; Klareskog L; Réthi B; Catrina AI; Diaz-Gallo L-M; Malmström V; Grönwall C
Article: ARTHRITIS & RHEUMATOLOGY. 2023;75(2):164-170

Combination of Two Monoclonal Anti-Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase-4-Dependent Manner.

Krishnamurthy A; Circiumaru A; Sun J; Kisten Y; Damberg P; Sakuraba K; Sandor K; Jarvoll P; Zhou T; Malmström V; Svensson CI; Hensvold A; Catrina AI; Klareskog L; Réthi B
Article: FRONTIERS IN MEDICINE. 2023;10:1146353

Molecular signature of methotrexate response among rheumatoid arthritis patients.

Brynedal B; Yoosuf N; Ulfarsdottir TB; Ziemek D; Maciejewski M; Folkersen L; Westerlind H; Müller M; Sahlström P; Jelinsky SA; Hensvold A; Padyukov L; Pomiano NV; Catrina A; Klareskog L; Berg L
Article: NATURE COMMUNICATIONS. 2022;13(1):4046

Single cell sequencing identifies clonally expanded synovial CD4+ TPH cells expressing GPR56 in rheumatoid arthritis.

Argyriou A; Wadsworth MH; Lendvai A; Christensen SM; Hensvold AH; Gerstner C; van Vollenhoven A; Kravarik K; Winkler A; Malmström V; Chemin K
Article: COMMUNICATIONS BIOLOGY. 2022;5(1):129

Three-dimensional spatial transcriptomics uncovers cell type localizations in the human rheumatoid arthritis synovium.

Vickovic S; Schapiro D; Carlberg K; Lötstedt B; Larsson L; Hildebrandt F; Korotkova M; Hensvold AH; Catrina AI; Sorger PK; Malmström V; Regev A; Ståhl PL
Article: FRONTIERS IN MEDICINE. 2022;9:824501

Prospective Studies on the Risk of Rheumatoid Arthritis: The European Risk RA Registry.

Studenic P; Hensvold A; Kleyer A; van der Helm-van Mil A; Pratt AG; Sieghart D; Krönke G; Williams R; de Souza S; Karlfeldt S; Johannesson M; Krogh NS; Klareskog L; Catrina AI
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:804822

Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology.

Sherina N; de Vries C; Kharlamova N; Sippl N; Jiang X; Brynedal B; Kindstedt E; Hansson M; Mathsson-Alm L; Israelsson L; Stålesen R; Saevarsdottir S; Holmdahl R; Hensvold A; Johannsen G; Eriksson K; Sallusto F; Catrina AI; Rönnelid J; Grönwall C; Yucel-Lindberg T; Alfredsson L; Klareskog L; Piccoli L; Malmström V; Amara K; Lundberg K
Article: FRONTIERS IN MEDICINE. 2022;9:774945

Rheumatic?-A Digital Diagnostic Decision Support Tool for Individuals Suspecting Rheumatic Diseases: A Multicenter Pilot Validation Study.

Knevel R; Knitza J; Hensvold A; Circiumaru A; Bruce T; Evans S; Maarseveen T; Maurits M; Beaart-van de Voorde L; Simon D; Kleyer A; Johannesson M; Schett G; Huizinga T; Svanteson S; Lindfors A; Klareskog L; Catrina A
Article: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):239

The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual "window of treatment success" in RA patients.

Marklein B; Jenning M; Konthur Z; Häupl T; Welzel F; Nonhoff U; Krobitsch S; Mulder DM; Koenders MI; Joshua V; Cope AP; Shlomchik MJ; Anders H-J; Burmester GR; Hensvold A; Catrina AI; Rönnelid J; Steiner G; Skriner K
Article: RMD OPEN. 2021;7(2):e001662

Tocilizumab decreases T cells but not macrophages in the synovium of patients with rheumatoid arthritis while it increases the levels of serum interleukin-6 and RANKL.

Chatzidionysiou K; Circiumaru A; Rethi B; Joshua V; Engstrom M; Hensvold A; Af Klint E; Catrina A
Article: FRONTIERS IN IMMUNOLOGY. 2021;12:627986

A Comprehensive Evaluation of the Relationship Between Different IgG and IgA Anti-Modified Protein Autoantibodies in Rheumatoid Arthritis.

Grönwall C; Liljefors L; Bang H; Hensvold AH; Hansson M; Mathsson-Alm L; Israelsson L; Joshua V; Svärd A; Stålesen R; Titcombe PJ; Steen J; Piccoli L; Sherina N; Clavel C; Svenungsson E; Gunnarsson I; Saevarsdottir S; Kastbom A; Serre G; Alfredsson L; Malmström V; Rönnelid J; Catrina AI; Lundberg K; Klareskog L
Article: RMD OPEN. 2020;6(2):e001278

Association between number and type of different ACPA fine specificities with lung abnormalities in early, untreated rheumatoid arthritis.

Joshua V; Hensvold AH; Reynisdottir G; Hansson M; Cornillet M; Nogueira L; Serre G; Nyren S; Karimi R; Eklund A; Sköld M; Grunewald J; Chatzidionysiou K; Catrina A
Article: BMC IMMUNOLOGY. 2020;21(1):27

Multi-HLA class II tetramer analyses of citrulline-reactive T cells and early treatment response in rheumatoid arthritis.

Gerstner C; Turcinov S; Hensvold AH; Chemin K; Uchtenhagen H; Ramwadhdoebe TH; Dubnovitsky A; Kozhukh G; Rönnblom L; Kwok WW; Achour A; Catrina AI; van Baarsen LGM; Malmström V
Article: ANNALS OF THE RHEUMATIC DISEASES. 2019;78(12):1621-1631

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts.

Sun M; Rethi B; Krishnamurthy A; Joshua V; Circiumaru A; Hensvold AH; Ossipova E; Grönwall C; Liu Y; Engstrom M; Catrina SB; Steen J; Malmstrom V; Klareskog L; Svensson C; Ospelt C; Wähämaa H; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2018;20(1):146

The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy.

Jonsson MK; Hensvold AH; Hansson M; Aga A-B; Sexton J; Mathsson-Alm L; Cornillet M; Serre G; Lillegraven S; Fevang B-TS; Catrina AI; Haavardsholm EA
Article: JOURNAL OF AUTOIMMUNITY. 2018;90:28-38

T cells are influenced by a long non-coding RNA in the autoimmune associated PTPN2 locus.

Houtman M; Shchetynsky K; Chemin K; Hensvold AH; Ramsköld D; Tandre K; Eloranta M-L; Rönnblom L; Uebe S; Catrina AI; Malmström V; Padyukov L
Article: RMD OPEN. 2018;4(1):e000641

Initial validation and results of the Symptoms in Persons At Risk of Rheumatoid Arthritis (SPARRA) questionnaire: a EULAR project.

van Beers-Tas MH; Ter Wee MM; van Tuyl LH; Maat B; Hoogland W; Hensvold AH; Catrina AI; Mosor E; Stamm TA; Finckh A; Courvoisier DS; Filer A; Sahbudin I; Stack RJ; Raza K; van Schaardenburg D
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):182

IgG Fc galactosylation predicts response to methotrexate in early rheumatoid arthritis.

Lundström SL; Hensvold AH; Rutishauser D; Klareskog L; Ytterberg AJ; Zubarev RA; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2017;19(1):19

Discovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis.

Shchetynsky K; Diaz-Gallo L-M; Folkersen L; Hensvold AH; Catrina AI; Berg L; Klareskog L; Padyukov L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2017;76(1):119-125

How well do ACPA discriminate and predict RA in the general population: a study based on 12 590 population-representative Swedish twins.

Hensvold AH; Frisell T; Magnusson PKE; Holmdahl R; Askling J; Catrina AI
Article: GENOME MEDICINE. 2016;8(1):124

High-specificity bioinformatics framework for epigenomic profiling of discordant twins reveals specific and shared markers for ACPA and ACPA-positive rheumatoid arthritis.

Gomez-Cabrero D; Almgren M; Sjöholm LK; Hensvold AH; Ringh MV; Tryggvadottir R; Kere J; Scheynius A; Acevedo N; Reinius L; Taub MA; Montano C; Aryee MJ; Feinberg JI; Feinberg AP; Tegnér J; Klareskog L; Catrina AI; Ekström TJ
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(10):1891-1898

Protective effect of HLA-DRB1*13 alleles during specific phases in the development of ACPA-positive RA.

van Heemst J; Hensvold AH; Jiang X; van Steenbergen H; Klareskog L; Huizinga TWJ; van der Helm-van Mil A; Catrina AI; Toes REM; Lundberg K; van der Woude D
Article: MOLECULAR MEDICINE. 2016;22:322-328

Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.

Folkersen L; Brynedal B; Diaz-Gallo LM; Ramsköld D; Shchetynsky K; Westerlind H; Sundström Y; Schepis D; Hensvold A; Vivar N; Eloranta M-L; Rönnblom L; Brunak S; Malmström V; Catrina A; Moerch UG; Klareskog L; Padyukov L; Berg L
Article: ANNALS OF THE RHEUMATIC DISEASES. 2016;75(4):721-729

Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss.

Krishnamurthy A; Joshua V; Haj Hensvold A; Jin T; Sun M; Vivar N; Ytterberg AJ; Engström M; Fernandes-Cerqueira C; Amara K; Magnusson M; Wigerblad G; Kato J; Jiménez-Andrade JM; Tyson K; Rapecki S; Lundberg K; Catrina S-B; Jakobsson P-J; Svensson C; Malmström V; Klareskog L; Wähämaa H; Catrina AI
Article: ARTHRITIS RESEARCH & THERAPY. 2015;17(1):239

Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate.

Hensvold AH; Joshua V; Li W; Larkin M; Qureshi F; Israelsson L; Padyukov L; Lundberg K; Defranoux N; Saevarsdottir S; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(9):1772-1777

Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation.

Ytterberg AJ; Joshua V; Reynisdottir G; Tarasova NK; Rutishauser D; Ossipova E; Haj Hensvold A; Eklund A; Sköld CM; Grunewald J; Malmström V; Jakobsson PJ; Rönnelid J; Padyukov L; Zubarev RA; Klareskog L; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2015;74(2):375-380

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins.

Hensvold AH; Magnusson PKE; Joshua V; Hansson M; Israelsson L; Ferreira R; Jakobsson P-J; Holmdahl R; Hammarström L; Malmström V; Askling J; Klareskog L; Catrina AI
Article: PLOS ONE. 2014;9(11):e113924

IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence.

Lundström SL; Fernandes-Cerqueira C; Ytterberg AJ; Ossipova E; Hensvold AH; Jakobsson P-J; Malmström V; Catrina AI; Klareskog L; Lundberg K; Zubarev RA
Article: ARTHRITIS & RHEUMATOLOGY. 2014;66(1):31-39

Structural changes and antibody enrichment in the lungs are early features of anti-citrullinated protein antibody-positive rheumatoid arthritis.

Reynisdottir G; Karimi R; Joshua V; Olsen H; Hensvold AH; Harju A; Engström M; Grunewald J; Nyren S; Eklund A; Klareskog L; Sköld CM; Catrina AI
Article: ANNALS OF THE RHEUMATIC DISEASES. 2011;70(10):1822-1825

Delays in assessment of patients with rheumatoid arthritis: variations across Europe.

Raza K; Stack R; Kumar K; Filer A; Detert J; Bastian H; Burmester GR; Sidiropoulos P; Kteniadaki E; Repa A; Saxne T; Turesson C; Mann H; Vencovsky J; Catrina A; Chatzidionysiou A; Hensvold A; Rantapää-Dahlqvist S; Binder A; Machold K; Kwiatkowska B; Ciurea A; Tamborrini G; Kyburz D; Buckley CD
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Letter: ANNALS OF THE RHEUMATIC DISEASES. 2023;82(5):724-726

Divergent and dominant anti-inflammatory effects of patient-derived anticitrullinated protein antibodies (ACPA) in arthritis development.

Raposo B; Afonso M; Israelsson L; Wähämaa H; Stålesen R; Wermeling F; Hensvold AH; Grönwall C; Rethi B; Klareskog L; Malmström V
Corrigendum: ARTHRITIS RESEARCH & THERAPY. 2021;23(1):255

Correction to: The citrullinated/native index of autoantibodies against hnRNP-DL predicts an individual "window of treatment success" in RA patients.

Marklein B; Jenning M; Konthur Z; Häupl T; Welzel F; Nonhoff U; Krobitsch S; Mulder DM; Koenders MI; Joshua V; Cope AP; Shlomchik MJ; Anders H-J; Burmester GR; Hensvold A; Catrina AI; Rönnelid J; Steiner G; Skriner K
Review: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(8):1921-1933

Towards prevention of autoimmune diseases: The example of rheumatoid arthritis.

Hensvold A; Klareskog L
Other: EUROPEAN JOURNAL OF IMMUNOLOGY. 2021;51(6):1309

Anca Catrina 1971-2021 Obituary

Klareskog L; Rethi B; Hensvold A; Wahamaa H; Jakobsson P-J
Letter: ANNALS OF THE RHEUMATIC DISEASES. 2018;77(6):e30

Challenging judgement of a low-positive ACPA test in the context of individuals at risk of RA.

Hensvold AH; Catrina AI
KI thesis / dissertation: 2016

Studies on the role of anti-citrullinated protein antibodies in rheumatoid arthritis

Hensvold, Aase Eline Haj

Anställningar

Anknuten till Forskning, Medicin, Solna, Karolinska Institutet, 2023-2025

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Medicine Doktorsexamen, Institutionen för medicin, Solna, Karolinska Institutet, 2016

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